title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Vaccination against typhoid fever with a live oral vaccine. | A Salmonella typhi gal E mutant, designated Ty 21a, has been developed on the basis of virulence and protection studies with similar Salmonella typhimurium mutants in mice. Gal E mutants are characterized by a block in the enzyme UDP-4-galactose-epimerase. They owe their outstanding immunizing capacity when used in li... | 782,975 | [
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Pancreatic polypeptide - a postulated new hormone: identification of its cellular storage site by light and electron microscopic immunocytochemistry. | A peptide, referred to as pancreatic polypeptide (PP), has recently been isolated from the pancreas of chicken and of several mammals. PP is thought to be a pancreatic hormone. By the use of specific antisera we have demonstrated PP immunoreactivity in the pancreas of a number of mammals. The immunoreactivity was local... | 782,992 | [
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Attempts at perfect normalization of glucose tolerance test of severe diabetics by artificial beta cell. | The artificial beta cell is a Glucose Controlled Insulin (and dextrose) Infusion System (GCIIS) for maintaining normoglycemia in diabetic conditions and other disturbances of metabolism. The insulin and dextrose infusion rates are calculated by a microcomputer according to the static glucose concentration (proportional... | 783,030 | [
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Chemical properties of antigen-dependent migration inhibition factor in mice. | Antigen-dependent migration inhibition factor produced in cultures of mouse lymph node lymphocytes was further characterized. It was found to bind to Concanavalin A and could be eluted by the appropriate sugar. The pI of the activity was found to be between 6-4 and 6-5 by isoelectric focusing. | 783,044 | [
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Reaction of the urinary tract to polypropylene sutures. | Cystotomies were performed on 99 mature guinea pigs and closed with polypropylene sutures. The bladders were removed at intervals from day 4 through day 144 postoperatively. They were studied with both light and electron microscopy. A localized mild, acute, inflammatory reaction was noted transitorily; it subsided betw... | 783,077 | [
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[Stimulation of autoantibody formation in pemphigoid due to proteolytic enzymes?]. | Following brief exposure of cryostat sections of human skin to proteolytic enzymes (papain or trypsin), there is an increase in the antibody binding capacity of the basement membrane zone for basement membrane zone antibodies of patients with bullous pemphigoid. In conjunction with findings published in the literature,... | 783,086 | [
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A tissue model for the study of cell proliferation parameters in vivo. | An intact tissue model which can be used for detailed microscopic studies, quantitative cytochemical analysis and biochemical analysis has been explored, using a number of cell proliferation parameters. The preparations consist of mesenterial "windows" from rats dispersed on object slides. A technique for determining, ... | 783,099 | [
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Shipping fever pneumonia in yearling feedlot cattle. | During each week of 1974, we surveyed, for illnesses and deaths, a continually changing population of yearling feedlot cattle that, for the year, totaled 407,000 animals. About 5.1% of the cattle sickened and, of these, 18.9% died. From the 3,943 fatalities, 1,988 necropsies were made. About 75% of the clinical diagnos... | 783,102 | [
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A new semisynthetic macrolide antibiotic 3-O-oleandrosyl-5-O-desosaminylerythronolide A oxime. | A new antibiotic, 3-O-oleandrosyl-5-O-desosaminylerythronolide A oxime (3) was produced from erythronolide A oxime (1) by the oleandomycin-producing culture, Streptomyces antibioticus ATCC 11891. The structure of 3 was determined by degradative studies and confirmed by X-ray analysis. Compound 3 was found to be less ac... | 783,104 | [
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Iron transport in Salmonella typhimurium LT-2: prevention, by ferrichrome, of adsorption of bacteriophages ES18 and ES18.h1 to a common cell envelope receptor. | Ferrichrome prevents adsorption of phages ES18 and ES18.h1 to cells of Salmonella typhimurium. Studies of albomycin-resistant mutants defective in both ferrichrome utilization and ES18.h1 adsorption suggest a sid gene may specify a receptor for both. | 783,114 | [
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Outer membrane of Escherichia coli K-12: differentiation of proteins 3A and 3B on acrylamide gels and further characterization of con (tolG) mutants. | Two classes of mutants, con and tolG, that appeared to be very similar in a number of respects have been shown to be identical and cotransducible with pyrD. By diethylaminoethyl-cellulose chromatography of the outer membranes, we have shown that the mutants are missing only protein 3A and retain protein 3B. Using con m... | 783,128 | [
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Temperature-sensitive ribonucleic acid polymerase mutant of Salmonella typhimurium with a defect in the beta' subunit. | Localized mutagenes of Salmonella typhimurium followed by a [3H]uridine enrichment procedure yielded a temperature-sensitive strain with a mutation in the rpo region of the chromosome. Ribonucleic acid (RNA) polymerase (EC 2.7.7.6; nucleoside triphosphate: RNA nucleotidyltransferase) purified from this mutant was consi... | 783,138 | [
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Mycoplasma phosphoenolpyruvate-dependent sugar phosphotransferase system: purification and characterization of the phosphocarrier protein. | The Mycoplasma phosphoenolpyruvate-dependent sugar phosphotransferase system consists of three components: a membrane-bound enzyme II, a soluble enzyme I, and a soluble phosphocarrier protein, HPr. The HPr has been purified to homogeneity by a combination of ammonium sulfate precipitations, gel filtration and diethylam... | 783,139 | [
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Genetic map position of the pdxH gene in Escherichia coli. | The gene for pyridoxine phosphate oxidase, pdxH, is located 1.2 min beyond aroD, proximal to trp. | 783,152 | [
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Effect of cations and anions on the steady state kinetics of energy-dependent Ca2+ transport in rat liver mitochondria. | The divalent cation ionophore A23187 has been used to investigate the kinetics of energy-dependent Ca2+ uptake by rat liver mitochondria under steady state conditions. During A23187-induced cyclic Ca2+ flux, the free Ca2+ concentration is adjusted using [ethylenebis(oxyethylenenitrilo)]tetraacetic acid (EGTA) buffers. ... | 783,158 | [
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Galloylglucoses of low molecular weight as mordant in electron microscopy. II. The moiety and functional groups possibly involved in the mordanting effect. | Synthetic pentamonogalloylglucose applied to fixed tissues acts as a mordant, inducing high and diversified contrast similar to that obtained with natural gallotannins of low molecular weight (LMGG). By the separate use of each of the two moieties of the galloylglucose molecule, it was found that gallic acid is the mor... | 783,173 | [
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Effects of luteinizing hormone releasing hormone (LHRH) upon bioactive and immunoreactive serum LH levels in normal subjects. | The effects of LHRH stimulation upon plasma LH levels measured by bioassay and radioimmunoassay were examined during the normal menstrual cycle, and in normal men and post-menopausal women. After administration of 100 mug LHRH by subcutaneous injection during the early follicular phase, a 2.7-fold rise in bioactive ser... | 783,183 | [
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Effects of selective media and atmosphere of incubation on the isolation of group A streptococci. | The effects of selective media and atmosphere of incubation on the isolation of group A beta-hemolytic streptococci were evaluated. Sheep blood agar medium with gentamicin (2.5 or 5.0 mug/ml) was inferior to antibiotic-free sheep blood agar medium. This resulted from the partial restriction of group A streptococcal gro... | 783,190 | [
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Comparison of the suppressive effects of elevated plasma glucose and free fatty acid levels on glucagon secretion in normal and insulin-dependent diabetic subjects. Evidence for selective alpha-cell insensitivity to glucose in diabetes mellitus. | To examine whether abnormal pancreatic alpha-cell function found in human diabetes mellitus may represent a selective insensitivity to glucose, plasma glucagon responses to hyperglycemia and elevation of plasma free fatty acid levels (both known suppressors of glucagon secretion) were compared in juvenile-onset, insuli... | 783,198 | [
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Rennin and pepsin in stomachs of rats (Rattus norvegicus). | The predominant protease in adult rat stomachs has a pH optimum of 2.0 to 2.3 which corresponds almost exactly to that of porcine pepsin. One-day-old rats have a protease with a pH optimum of 3.8 to 4.2 similar to that of calf rennin. The pH optimum of rat stomach proteases decreases with age, and at 28 days it is simi... | 783,220 | [
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C4 synthesis in C4-deficient guinea pig radiation chimeras: restoration of the classic complement pathway. | Bone marrow transplants from normal Albany strain guinea pigs established a functional classical pathway of complement (C) in C4-deficient (C4D) guinea pigs. Seventeen days after transplant the Albany leads to C4D chimeras had detectable C4 and total hemolytic C activities. Maximum C4 levels (2 to 8% of normal were rea... | 784,873 | [
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A raft technique for chemotaxis: a versatile method suitable for clinical studies. | We describe a raft technique for the study of chemotaxis which possesses a number of advantages over the use of chambers. Membranes are laid on pads soaked in chemotactic agent and cells are contained in plastic cups, which are inverted on to the membrane. This method gives results which are similar to those obtained i... | 784,880 | [
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[Bond strength between nonprecious metal alloy and porcelain. Part (1). Bond strength with press condensing method (author's transl)]. | For the purpose of finding out the method which is able to evaluate nonprecious metal/porcelain bond strength easily, Ceramco procelain was fused to casted Wiron "S" (3 mm diameter), by means of 5 types of press condensing methods; the bond strength was measured by pull out method and these condensing methods were comp... | 784,884 | [
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Tympanic reconstruction. Fifteen year report on tympanoplasty. Part II. | This survey was carried out to evaluate techniques in current use for the treatment of chronic suppurative otitis media. Part I concerns the incidence of cholesteatomatous complications following combined approach tympanoplasty (CAT). Residual and Recurrent cholesteatoma occurred much more frequently than had been expe... | 784,887 | [
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Gentamicin and albumin-bilirubin binding. An in vivo study. | Ten newborn infants were given gentamicin intramuscularly. Over a postinjection interval of 12 hours, no significant change occurred in the total binding capacity of serum albumin for bilirubin or in concentrations of serum bilirubin levels. There was no correlation between concentrations of serum gentamicin and the to... | 784,927 | [
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The facade compulsive: a diagnostic formulation derived from projective testing. | A psychological "type" characterized by repetitive and compulsive action tendencies but not by obsessive thoughts was delineated. It was shown how this syndrome could be identified through differential inter-test patterning on projective techniques. The possibility of improving psychodiagnostic accuracy by stipulating ... | 784,938 | [
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Predicting clinical judgment for a primary grade apperception battery. | A six-card Primary Grade Apperception Battery (three cards from the CAT and three from the SAM) was administered to one group of first grade children on a 4 month test-retest schedule and to a new group of first graders 1 year later. Two clinical psychologists read the protocols and made clinical judgments regarding ho... | 784,941 | [
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Sociopathy, self-actualization, and time. | Male sociopaths (n = 15), and self-actualizers (n = 15) ages 18-30, were compared on 18 measures of temporal behavior obtained from estimation, projective, and questionnaire techniques. Subjects differed significantly on half of these measures including time accuracy, delay, dominance, relatedness, and evaluation of th... | 784,943 | [
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Observations on cavity liners for composite resin restorations. | Adhesion or surface roughness and discoloration at the interface between pulpinsulating materials and composite resins were taken as indications for interaction between the resins and the insulating materials. Some interaction occurred between all insulating materials and resins investigated. After separation of the re... | 784,958 | [
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The infection of rat tongue mucosa in vitro with five species of Candida. | Orthokeratinised mucosa from the dorsal surface of neonatal rat tongue was maintained in culture and then infected with Candida albicans, C. tropicalis C. krusei, C. parapsilosis or C. guilliermondii for up to 45 h. The five species showed varying abilities to invade the tissues, which appeared to reflect their differe... | 785,002 | [
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Persistence of mumps viral antigens in mouse brain. | Newborn mice were infected intracerebrally with a fresh isolate of mumps virus. Although infectious virus could not be recovered after the acute infection, direct immunofluorescence demonstrated the persistence of mumps antigens for up to 100 days after the initial infection. | 785,062 | [
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Further studies on the lethal effect of long-chain fatty acids on mycobacteria. | Mycobactericidal activity of long-chain fatty acids was confirmed by in vitro exposure of BCG. The killing effect was accompanied by inhibition of the membrane-bound acid phosphatase activity. Such active fatty acids were those having a stronger hemolytic activity (e.g., C12:0, C14:0, C18:1, C18:2). Heat-killed BCG cel... | 785,063 | [
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[Urgent keratoplasty for a corneal infection by actinomyces (author's transl)]. | A 41-year-old man suffering from an actinomyces infection of the cornea of his right eye, was treated unsuccessfully with antibiotics especially intensive local and systematic therapy with penicillin, paracentesis of the anterior chamber with penicillin irrigation, and cautery of the corneal ulcer were fruitless. Final... | 785,086 | [
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Tuberculosis in renal transplant patients. | Infection of two renal transplant recipients with tuberculosis is reported. Autopsy findings are available in one case. The frequency of tuberculosis in such cases, treatment problems and prevention are discussed. | 785,170 | [
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[Significance of indirect hemagglutination test with polyvalent E. coli O antigens to diagnosis of pyelonephritis (author's transl)]. | 78% of 32 patients with acute E. coli pyelonephritis had significantly increased antibody titers to polyvalent E. coli antigens (PA). Only 14% of 42 patients with chronic E. coli pyelonephritis had increased antibody titers. 143 E. coli O groups were used in hemagglutination test distributed into 8 antigen pools. Antib... | 785,184 | [
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... |
Cytological and genetic studies of the life cycle of Saccharomycopsis lipolytica. | In the alkane yeast Saccharomycopsis lipolytica (formerly: Candida lipolytica) the variability in the ascospore number is caused by the absence of a correlation between the meiotic divisions and spore wall formation. In four spored yeasts, after meiosis II, a spore wall is formed around each of the four nuclei produced... | 785,204 | [
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Effects of elevation of strain-ploidy on transmission and recombination of mitochondrial drug resistance genes in Saccharomyces cerevisiae. | In order to study the effects of strainploidy on the transmission and recombination of the mitochondrial genes C, E and O conferring the resistance to chloramphenicol, erythromycin and oligomycin, respectively, haploids were crossed to diploids and the results of genetic analysis were compared with those from haploid X... | 785,208 | [
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Effect of glucose starvation on the expression of transferred tsx genes in Escherichia coli K12 zygotes. | Escherichia coli K12 Hfr H Tsxs Strs and F- Pro- Tsxr His- Arg- Strr bacteria were conjugated in the absence of arginine with or without glucose. The efficiency of conjugation, measured by the frequency of Pro+ and His+ recombinants was not affected. Arginine starvation alone did not affect the tsxs gene expression whi... | 785,225 | [
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Effect of chloramphenicol and the recB gene product on DNA metabolism in Escherichia coli K12 strains defective in DNA ligase. | We have examined DNA strand breakage, DNA degradation, and the rate of DNA synthesis in lig and lig-recB strains of Escherichia coli K12 incubated in the presence and absence of 3 mug/ml chloramphenicol. Substantial DNA strand breakage and DNA degradation is observed in the lig strain upon growth at 40 degrees C; howev... | 785,229 | [
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[Intramolecular mobility of pepsin]. | By modifying four tyrosine residues in pepsin a derivative (aminopepsin) is obtained which is capable to conjugate with a fluorescent label DNS-Cl without loss of the catalytic activity. Rotational relaxation times of native pepsin and dansylated aminopepsin (DAP) are measured by a fluoresence polarization method. The ... | 785,236 | [
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[Chromosome structure, histones and gene activity in Drosophila]. | The problem to be reviewed in this study concerns the mechanism of regulation of gene activity relied on the structural changes of the chromatin. The role of histones in the regulation of transcription is discussed on the basis of the results obtained by the authors and literature data. In particular, the results are p... | 785,238 | [
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[Two stages in the digestion of proteins by pepsin]. | Studies on a monosubstrate system (pepsin - substrate) yielded values which characterize pepsin digestion as a multi-stage process. During the first stage, pepsin hydrolyzes the most accessible parts of the protein molecule, i.e., those portions of the peptide chains which are situated on the surface of the globule. Du... | 785,266 | [
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Potentiation of lordosis behavior by intrahypothalamic infusion of synthetic luteinizing hormone-releasing hormone. | Saline and luteinizing hormone-releasing hormone (LRH) were infused into the medial preoptic area (MPOA), arcuate nucleus (ARC), lateral hypothalamic area (LHA) and the cerebral cortex (CC), and the effects on sexual behavior were studied in estrone- (E-) primed ovariectomized (OVX) female rats. Each cannulated, OVX fe... | 785,295 | [
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Computer data processing in the examination of retinal vessels in essential hypertension and atherosclerosis. | The mean retinal venoarterial width ratio in 100 healthy subjects was measured with a PZO stereoscopic microscope equipped with a calibrated ocular and with an automatic digital image transformer coupled with an ODRA 1204 computer. The mean value was estimated as equal to 1.21 with an SD of 0.071. The same study was pe... | 785,329 | [
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Personality dimensions measured by projective techniques: a formulation based on structural analysis. | It is suggested that a better understanding and more effective use of projective techniques can be achieved by viewing each test in terms of the depth of personality assessed and its unique amalgamation of emotional and intellectual aspects of personality. With these considerations in mind, a refurbished definition of ... | 785,365 | [
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Breast reconstruction after a radical mastectomy. | A method of breast reconstruction, following a radical mastectomy, used a tubed flap of the tissue usually discarded during an abdominal lipectomy. This places the donor scar in an unnoticeable position. After migration, maneuvers such as denuding portions for insertion and overlap, and using a wrist attachment, have b... | 785,497 | [
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[Sterilization by ionizing radiations (author's transl)]. | The first part summarizes the general characteristics of ionizing radiations and their activity on microorganisms: lethal and mutagenic effects, sensitivity conditions. Different microbial species have different sensitivities: gram negative bacteria are more sensitive (D10 approximately 5-10 Krads), bacterial spores an... | 785,552 | [
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A comparative study to evaluate three separate computer programs for electrocardiographic interpretation. | To compare the efficiency and accuracy of three separate computer programs for interpreting electrocardiograms, 50 EKGs run on patients hospitalized in our institution were transmitted to each of the three participating computer programs. The EKGs were then inspected individually by three cardiologists who later correl... | 785,612 | [
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Pregnancy in renal transplant recipients. | Of the 48 female patients attending the outpatient clinic of the Johannesburg General Hospital Transplant Unit between January 1971 and December 1974, 10 became pregnant. Fifteen pregnancies were recorded, 6 of which ended in abortions. Ten infants were born from the remaining 9 pregnancies and 4 (40%) died in the neon... | 785,622 | [
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Vaccine and Mycostatin in treatment of cryptococcosis of the respiratory tract. | Three cases of respiratory crytococcosis are described, one diagnosed only after thoracotomy and two after cytology. All were confirmed by cultures, biological and biochemical tests. The patients are alive and well 14 years, 5 years, and 5 years after treatment with crytococcal vaccines and mycostatin. Vaccines proved ... | 785,628 | [
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Atigenic similarity between Ceratocystis species and Sporothrix schenckii as observed by immunofluorescence. | Antigenic properties of Sporothrix schenckiii and 2 species of Ceratocystis (C. stenoceras and C. ulmi) were compared by indirect immunofluorescent staining technique. Both species of Ceratocystis and 2 strains of S. schenckii reacted equally well with the unabsorbed antisera against 2 strains of S. schenckii, indicati... | 785,629 | [
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Pulmonary embolism. | Pulmonary embolism is a common and often fatal postoperative complication. Dyspnea is the most common clinical manifestation in pulmonary embolism, and other signs are frequently inconsistent and often vague. The chest film and electrocardiogram may be helpful in excluding other cardiorespiratory diseases but they are ... | 785,636 | [
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Visually evoked potentials: theory, techniques and clinical applications. | The visually evoked potential (VEP), the recording of which has recently been made possible by the development of computer averaging techniques, is a gross electrical signal generated by the occipital region of the cortex in response to visual stimulation. It is more specific than the electroencephalogram (EEG) and mor... | 785,653 | [
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Fibrin degradation products in renal diseases. | Levels of serum fibrin degradation products (FDP) were determined in patients with acute nephritis, chronic nephritis, lupus nephritis and toxemia of pregnancy by the passive hemagglutination inhibition test. Serum FDP levels were less than 10 mug/ml in normal control adults, averaging 3.2 +/- 1.2 mug/ml. The incidence... | 785,695 | [
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Antigen inhibition on antibody forming cells at the level of effector cell. | In this study a possibility was examined that the specific antigen might inhibit antibody forming cells in order to know whether a non-T-cell-dependent mechanism of self-tolerance is present or not. If an autoantigen inhibits autoantibody forming cells, this inhibition may be one of the non-T-cell-dependent mechanisms ... | 785,697 | [
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[Summary of work session 1: Blood coagulation in gastroenterology]. | Part I: Immunological assays of clotting factors in the diagnosis of liver diseases. The immunological determination of Antithrombin III is a good measure of the capacity of the liver to synthesize plasma proteins. Antithrombin III concentration in serum correlated significantly with the prothrombin time and the activi... | 785,839 | [
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Effects of androstenes, 5alpha-androstanes, 5beta-androstanes, oestrenes and oestratrienes on serum gonadotrophin levels and ventral prostate weights in gonadectomized, adult male rats. | The morphologic and metabolic effect of a single intracutaneous injection of homologous endocrine pancreas in Freund's complete adjuvant (CFA) was studied in 100 mice and compared with control groups which had been (1) immunized with murine insulin in CFA, (2) injected with CFA alone, or had (3) received no treatment. ... | 785,923 | [
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Diazepam in emulsion form for intravenous usage. | Since aqueous solutions of diazepam were introduced into clinical practice, the problem has arisen of local vascular side effects after intravenous injection. A new preparation of diazepam as a lipid emulsion is presented. It was prepared by Vitrum and shows many similarities to Intralipid. A clinical trial was designe... | 785,929 | [
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IgA levels and carrier rate of Haemophilus influenzae and beta-haemolytic streptococci in children undergoing tonsillectomy. | Studies of IgG, IgA, IgM and IgE in serum and of IgG, IgA and IgM in saliva were performed in 52 children undergoing tonsillectomy. The results revealed that levels of IgA in serum and saliva in the patients were significantly reduced as compared with levels in age- and sex-related healthy controls (p less than 0.001 a... | 785,944 | [
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Synergistic effect of alloantibodies or F(ab')2 and prednisone on murine split heart allograft survival. | Heterotopic grafting of split allogeneic mouse hearts across a strong H-2 barrier (A/Sn leads to A.CA) was used in a study of alloantibody or F (ab')2 induced enhancement. Strong specific binding of alloantibodies occurred in the graft. A marked synergistic effect on graft survival was observed after combined treatment... | 785,946 | [
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Maintenance therapy with a new retard tablet preparation of procainamide. | The procainamide plasma concentration was followed during maintenance therapy with a new procainamide retard tablet preparation in 23 hospitalized patients suffering from acute or chronic coronary heart disease with complicating ventricular arrhythmias. After initial individually adjusted treatment with Pronestyl every... | 785,987 | [
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The endoscopy corner: removal of foreign bodies from the upper intestinal tract with fiberoptic instruments. | Endoscopic removal of ingested foreign bodies should be attempted if the object is not spontaneously passed through the pylorus. This can be safely accomplished with the wire snare technic, or with special grasping forceps that are currently available. | 786,008 | [
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Mercury toxicity in the pregnant woman, fetus, and newborn infant. A review. | This paper reviews the reported cases of mercury poisoning in pregnancy and the data based on sources of contamination, maternal uptake, and distribution. It analyzes current knowledge of placental transfer of various mercury compounds, fetal uptake, and distribution. It identifies the embryopathic and fetal toxic effe... | 786,026 | [
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Diet and atherosclerosis. | Because of the statistical establishment of elevated blood lipids as a risk factor in the development of atherosclerotic heart disease, most of the attempts to regulate blood lipids by diet are centered on the fat in the diet. The levels of blood lipids and the course of experimental atherosclerosis can be affected by ... | 786,036 | [
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Studies on the ability of acetylcholine receptors to bind alpha-bungarotoxin after exposure to myasthenic serum. | The purpose of the present experiment was to determine if there is a factor in serum of patients with myasthenia gravis (MG) that interferes with binding of (125I)-alpha-bungarotoxin to acetylcholine receptors of normal mouse diaphragm. Diaphragms were incubated aerobically for 1 hour in either Krebs-Henseleit solution... | 786,110 | [
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Myasthenia gravis: the role of immunological deficiency. | To evaluate further the association between myasthenia gravis and humoral immune deficiency, 92 sera from myasthenic patients were tested so as to determine titers against commensal E. coli, isohemagglutinin titers, and IgG and IgM concentrations. Results were compared with those obtained from normals, disease controls... | 786,114 | [
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The role of humoral and cellular immune factors in neuromuscular block in myasthenia gravis. | The neuromuscular block of myasthenia gravis appears to be due to decreased and abnormal responsiveness of the motor end plates to transmitter, and perhaps a decreased number of functioning end plates. The presence in myasthenic patients of serum globulins that bind to a bariety of cellular and subcellular components, ... | 786,115 | [
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Immunological studies in sarcoidosis: a comparison of in vivo and in vitro Kveim tests. | No migration inhibition was observed in the 46 patients or the 12 controls when the Danish Kveim antigen was used in the LMAT. No migration inhibition was found in 23 of the same patients when the LMT was employed using the same antigens (Table 3). | 786,129 | [
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[The colibacillosis of the pig (author's transl)]. | A review of recent knowledges of the specific determinants of Escherichia coli pathogenicity allows the development of new effective immunisation against the colibacillosis of the pig. Especially experimental and field trials provide promising results by oral or parenteral vaccinations, with attenuated bacteria neutral... | 786,133 | [
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Treatment of psoriasis with topically applied tretinoin and steroid ointment. | The sequential application of tretinoin and a corticosteroid ointment was considerably more effective in the treatment of plaque-type psoriasis than either drug alone in a pilot study. The best results were obtained with 0.3% tretinoin followed by a potent corticosteroid ointment. Combined therapy was particularly effi... | 786,170 | [
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Coliform meningitis in the newborn. | Thirty-six patients with coliform meningitis in the 15-year period 1960-1974 are reported. Only 9 patients survived unscathed though the other 5 survivors were not seriously affected. During the septicaemic phase of the illness the cerebrospinal fluid (CSF), though positive on culture, may be otherwise normal. Meningit... | 786,182 | [
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Infantile cortical hyperostosis. | The genetic aspects of infantile cortical hyperostosis are discussed. A pedigree is presented, based on the history and clinical and radiological investigations of all living members of the family, with data from 11 cases with the condition in two generations, and one possible case from a third generation. The data sug... | 786,183 | [
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Utilization of acrylate-embedded large tissue samples in dermatohistology. | A method of embedding tissue in synthetic material which has seldom been used in dermatohistology is described in this communication. This process combines the preparative advantage of slight artifactual alteration of organic tissue and readily reproducible sections between 1 and 3 mu in thickness with the feature of l... | 786,184 | [
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[Artificial intranasal bacterial invasion in the newborn calf. 1. Quantitative assessment of nasal secretion for certain groups of bacteria]. | A technique has been developed for quantitative assessment of nasal secretion for the presence of specified groups of bacteria, as a contribution to microbiological treatment of the problem of artificial intranasal bacterial invasion in newborn and nursed calf. Some 10(6) to 10(7) bacteria were recorded from each gram ... | 786,200 | [
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... |
Efficacy of repeated pharmacotherapy in experimental acute poisonings with fluostigmine. | The effectiveness of repeated pharamacotherapy in acute poisonings with fluostigmine was studied in rats. It was demonstrated, that the second i.p. administration of obidoxime (40 mg/kg) was without effect. Repeated i.p. administration of atropine (10 mg/kg) shown marked efficacy only in animals treated previously with... | 786,218 | [
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Simultaneous determination of influenza virus antihemagglutinin and antineuraminidase antibodies by means of the combined photometric ACU method I. conduct of test. | A modification of the photometric ACU (antibody concentration unit) method designated as combined ACU test is described by means of which the titers of both antihemagglutinin (AH) and antineuraminidase (AN) antibodies can be simultaneously determined, using intact homologous influenza virus. In addition, the constants ... | 786,219 | [
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The effect of dazomet on salmonellas on artificially contaminated eggs. | Salmonellas were isolated from the surface of only 1 of 21 artificially contaminated eggs after they had been treated with dazomet. By comparison salmonellas were isolated from the surface of 13 of the 21 untreated eggs. Penetration by the salmonellas through the shells to the shell membranes resulted from the immersio... | 786,239 | [
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[Betaines of quaternary salts of pyridine-2-and -4-aldoxim (author's transl)]. | The monobetaine derived from the AChE-ractivator bis-[4-hydroxyiminomethyl-pyridinium-(1)-methyl]-either dichloride (obidoxim; Toxogonin), was shown to be in solution an intramolecular CT-complex. Some betaines of quaternary salts of pyridine-aldoximes were isolated. | 786,301 | [
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[On the efficacy of carbocromen in the treatment of myocardial infarction (author's transl)]. | Comparative clinical trials on 100 infarcted patients have demonstrated the therapeutic superiority of 3-(2-diethylamino-ethyl)-4-methyl-7-(carbethoxy-methoxy)-2-oxo-1,2-chromene-hydrochloride (carbocromen; Intensain). 50 patients were treated eith carbocromen and 50 with papaverine as controls. Overall improvement und... | 786,302 | [
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Significance of persisting serologic abnormalities in SLE. | The significance of abnormal serum anti-DNA and complement levels persisting in SLE patients on treatment has been explored. Instances when serologic abnormalities returned to normal were followed by a significantly longer mean duration of remission. When anti-DNA persisted at abnormal levels, a more severe exacerbatio... | 786,295 | [
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Comparison of the complement-fixing activity of antinuclear antibodies in lupus nephritis, mixed connective tissue disease, and scleroderma. | Complement-fixing antinuclear antibody (CFANA) titers were measured in 18 patients with lupus nephritis and were compared to titers in 22 patients with scleroderma and mixed connective tissue disease (MCTD) who had comparable ANA titers but lacked nephritis. CFANA titers were higher in SLE patients with nephritis than ... | 786,297 | [
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Isolation and properties of 6-phosphogluconate dehydrogenase from Escherichia coli. Some comparisons with the thermophilic enzyme from Bacillus stearothermophilus. | 6-Phosphogluconate dehydrogenase (6-phospho-D-gluconate:NADP oxidoreductase (decarboxylating), EC 1.1.1.44) of Escherichia coli MREp 600 has been isolated with the purpose of carrying out comparative studies with the thermostable enzyme previously isolated from Bacillus stearothermophilus (Veronese, F.M., Boccù, E.,Fon... | 786,365 | [
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Energy metabolism of Saccharomyces cerevisiae discrepancy between ATP balance and known metabolic functions. | The contribution of metabolic pathways to the catabolism of glucose, galactose and ethanol by Saccharomyces cerevisiae in aerobiosis has been studied. The results suggest that: 1. Of the total ATP formed in catabolism yeast obtain as much as 60% from ethylic fermentation during logarithmic growth on glucose. However, a... | 786,371 | [
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0.2028748,
0.2859373,
-0.08771349,
-0.2458767,
0.1062153,
-0.433825,
-0.1847148,
0.2068712,
-0.4784835,
0.1159804,
-0.4733236,
0.4099211,
-0.1088577,
-0.4333726,
0.5020677,
0.1911698,
-0.3548337,
-0.0... |
Permeability to cobalt ions and action of colicin K in a mutant that overproduces cardiolipin. | A mutant of Escherichia coli that produces excess cardiolipin becomes less capable of transporting Co2+. Cardiolipin therefore does not act as an ionophore under these conditions. Colicin K brings about the typical increase in permeability to Co2+ in the mutant. | 786,375 | [
-0.2151279,
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0.2997482,
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0.3762125,
-0.1204647,
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Simultaneous allotransplantation of kidney and spleen in dogs with or without previous splenectomy. | 29 simultaneous kidney and spleen transplantations have been performed on dogs. Time of rejection, similar for both organs, occurs in a delay very close to the control series. No statistically difference of the day of rejection was observed in relation with the implantation of the spleen either on the iliac or on the m... | 786,396 | [
-0.03361861,
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0.1137256,
0.005045618,
0.1567403,
0.076... |
Capillary migration of the cells of three murine tumours. | Cells of a murine myeloid leukemia, a lymphoid leukaemia, and a reticulosarcoma, were tested for their ability to migrate from capillary tubes. As compared with normal cells from the speeen, bone marrow, lymph nodes or peritoneal exudate, tumour cells migrated rather poorly. When present, the migration could be attribu... | 786,398 | [
-0.08994927,
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0.4093239,
0.4768782,
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0.2114023,... |
Allogeneic marrow grafting for treatment of aplastic anemia: a follow-up on long-term survivors. | Eleven of twenty-four patients with severe aplastic anemia given marrow grafts from HLA-identical siblings between October 1970 and March 1973 are alive with normal marrow function and continued evidence of engraftment 3-5 yr later. Ten have been leading normal lives with no immunosuppressive or other drug therapy sinc... | 786,410 | [
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0.1783535,
0.2197523,
0.3217441,
-0.242763,
-... |
Intracardiac electrography in endocardial cushion defects. | Conduction of the sino-atrial impulse from the high right atrium to the ventricles was studied by intracardiac electrography in 21 unoperated patients, age 3 months to 11 years, with endocardial cushion defects (ECD). The high right atrium-to-low right atrium conduction time was prolonged in 15 of 18 subjects (mean 57 ... | 786,499 | [
-0.06493189,
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0.4070718,
0.4360961,
-0.01913051,
... |
Liver cell surface localization of hepatitis B antigen and of immunoglobulins in acute and chronic hepatitis and in liver cirrhosis. | This paper describes immunofluorescence studies on liver cell surface localization of hepatitis B surface antigen (HBsAg) and of IgG in acute and chronic hepatitis and in cirrhosis. In acute hepatitis B, HBsAg was found at the surface of hepatocytes in an early phase of the disease, but not during the recovery. This fi... | 786,518 | [
0.04795364,
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0.05717835,
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0.06023305,
0.3102593,
0.07921734,
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0.1700241,
0.06628954,
-0.2364501,... |
Heterogeneity of stem cells in severe combined immunodeficiency. | Two patients with severe combined immunodeficiency disease (SCID) having variable B-cell development have been shown to have marrow precursors of lymphoid cells which can be induced in vitro by thymic factors to express certain T-cell surface characteristics (HTLA+ phenotypes). Their marrow cells could not, however, be... | 786,520 | [
-0.01555867,
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0.0005534988,
0.3194778,
0.3224754,
0.100042,
-0.05992233,
... |
Cancer of the nose: ablation and repair. | Cancer of the nose is very common and lesions seen by reconstructive surgeons are often recurrent and extensive. Surgical removal of cancer of the nasal skin can usually be accomplished under local anesthesia, and in most instances frozen section histologic examination should be used to confirm the adequacy of excision... | 786,530 | [
0.03416398,
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0.09830404,
0.02504142,
0.4231454,
0.0381596,
0.1872928,
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0.01573921,
0.1042276,
0.2352935,
0.3422245,
0.01495687... |
Formation of dolichol monophosphate 2-deoxy-D-glucose and its interference with the glycosylation of mannoproteins in yeast. | A crude membrane fraction from Saccharomyces cerevisiae has been found to catalyze 2-deoxy-D-glucose transfer from GDP-2-deoxy-D-glucose to endogeneous lipid and glycoprotein acceptor. Evidence will be represented that the glycolipid formed has properties characteristic dolichol monophosphate 2-deoxy-D-glucose. The 2-d... | 786,621 | [
-0.127114,
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0.1868545,
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0.1390026,
0.1069443,
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0.03659239,
0.1357844,
0.2054083,
0.3772475,
0.2435101,
-0.211822,
-0.... |
Purification, subunit structure and partial amino-acid sequence of anthranilate-5-phosphoribosylpyrophosphate phosphoribosyltransferase from the enteric bacterium Serratia marcescens. | The enzyme anthranilate-5-phosphoribosylpyrophosphate phosphoribosyltransferase from Serratia marcescens was purified to apparent homogeneity. The purification procedure included ammonium sulfate precipitation, DEAE-cellulose chromatography, Sephadex gel filtration and hydroxyapatite chromatography. The molecular weigh... | 786,623 | [
-0.1419471,
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0.07032673,
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0.1839467,
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0.2494954,
0.2870837,
0.04828226,
0.3092067,
0.07943772,
0.07192362,
... |
DNA-dependent DNA polymerase from yeast mitochondria. Dependence of enzyme activity on conditions of cell growth, and properties of the highly purified polymerase. | The activity of DNA polymerase was determined in gradient-purified mitochondria from yeast cells grown under a variety of conditions. The specific enzyme activity was found to be dependent on the degree of aeration of the cells, and on the carbon source used for the medium. It was sensitive to glucose repression, and w... | 786,635 | [
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0.04242105,
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0.08743059,
0.2350967,
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0.1959894,
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0.4570849,
0.7865421,
-0.04311723,
-0.01089358,
... |
Molecular organization in bacterial cell membranes. Sulfhydryl groups and disulfide bridges in Streptomyces albus and Escherichia coli K 12 cytoplasmic membranes. | Plasma membranes from Streptomyces albus had 5.2 mol of sulfhydryl groups and 6 mol of disulfide bridges/50 kg proteins whereas Escherichia coli membranes had 3.4 mol sulfhydryl groups and 4 mol disulfide bridges/50 kg protein. About 66% of the sulfhydryl groups of S. albus membranes and 22% of those of E. coli membran... | 786,637 | [
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0.2074375,
0.05667913,
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0.195894,
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0.2764335,
0.08057803,
0.102572,
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0.2447101,
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0.04609906,
0.1079759,
0.2982381,
0.06294417,
-0.1732639,
-... |
Restriction-enzyme-cleavage maps of bacteriophage M13. Existence of an intergenic region on the M13 genome. | Replicative form DNA of bacteriophage M13 was cleaved into specific fragments by an endonuclease isolated from Hemophilus aegyptius (endoR.HaeII) and an endonuclease from Arthrobacter luteus (endoR.AluI). The fragments were ordered as to construct a circular map of the phage M13 genome by: (a) using each fragment as a ... | 786,638 | [
-0.001393701,
0.1567762,
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0.03455432,
0.1673075,
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0.2571568,
0.2673387,
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0.1336466,
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0.2298597,
0.05099083,
-0.5093923,
0.4420565,
-0.2487623,
-0.334922,
... |
Ex vivo surgery on the renal allograft. | Ex vivo surgery has brought an important contribution to the solution of renovascular problems. In our experience, the simplest application of ex vivo surgical techniques has been the revision of the arterial anatomy of the renal allograft to facilitate subsequent implantation into the recipient. We report herein four ... | 786,648 | [
-0.1850842,
0.001779234,
-0.5398363,
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0.1450838,
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0.1140095,
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0.2366531,
0.1543804,
-0.091317... |
Urological complications in renal transplantation. | The urological complications associated with 128 consecutive renal transplants performed in the Department of Urology of the University Hospital Heidelberg between February 1967 and January 1975 are described. Extravesical ureteroneocystostomy has shown to be the preferable method for urinary tract reconstruction, prov... | 786,653 | [
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0.2122879,
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0.3862519,
0.2724218,
0.02810343,
... |
Reconstruction of the ureter: a review of operative and functional aspects. | The importance of the urodynamic characteristics of the ureter are considered after plastic and reconstructive operations. Choice of the most suitable method is as important as good operative technique. The partial replacement of the lower end of the ureter by a bladder flap shows good results. Different types of bladd... | 786,657 | [
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0.07565369,
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0.1656878,
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0.3489385,
0.1455462,
0.02398392,
... |
Biotransformation and pharmacokinetics of sulfinpyrazone (Anturan) in man. | The absorption, biotransformation and elimination of sulfinpyrazone, 1,2-diphenyl-3,5-dioxo-4-(2'-phenylsufinylethyl)-pyrazolidine, have been studied by administration of single 200 mg oral doses of a 14C-labelled preparation to two male volunteers. Absorption from the gastro-intestinal tract was rapid and complete and... | 786,687 | [
-0.4882734,
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0.0305704,
0.5975055,
0.1122166,
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0.1546238,
0.07936273,
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0.2087709,
0.1962232,
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0.279926,
0.2168704,
0.3794639,
0.2998118,
0.315737,
-0.1499676,
-0.086895... |
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