title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Transitory monoclonal gammaopathy after smallpox vaccination]. | The case is described of a 51-year-old female who developed monoclonal gammopathy of IgMk-type following smallpox vaccination. The Mcomponent was detectable, albeit in decreasing concentrations, over a period of 10 months and then disappeared spontaneously. The findings are discussed in relation to "essential" paraprot... | 825,962 | [
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Radiation therapy for rectal carcinoma. | Rectal adenocarcinoma is a radiosensitive tumor. Radiation therapy can be safely given with acceptable tolerance during treatment. In clinically operable patients, this pretreatment appears to increase long-term survival by 43% or better. In symptomatic patients with primary inoperable recurrent disease, control of com... | 825,966 | [
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The effects of transplacental and mammary movement of PCBs on infant rhesus monkeys. | Sixteen adult female rhesus monkeys were fed diets containing 2,5 and 5.0 ppm PCB (Aroclor 1248) for approx. 1.5 years. 6 of the 8 animals on 5 ppm PCB and 8 of the 8 animals on 2.5 ppm PCB conceived when bred after 6 months' exposure to PCB. Only 1 live infant was born to the animals of the 5.0 ppm group and 5 infants... | 825,993 | [
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[Therapy of organophosphate poisoning in animals]. | Per os intoxication of sheep with O-ethyl S-(2-dimethylaminoethyl)methyl phosphonium thioate (EDMM) in the dose of 0.209 mg per kg of live weight, that means p.o. LD50 (2 h), can be therapeutically mastered by means of an antidotal mixture of the reactivator of cholinesterase (trimedoxim) and of the cholinolytic (atrop... | 826,002 | [
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Evaluation of paracetamol-induced damage in liver biopsies. Acute changes and follow-up findings. | In 100 patients who had taken an acute overdose of paracetamol the liver was biopsied percutaneously on the 4th day or as soon thereafter as recovery of the clotting mechanism allowed. A system for grading the histological changes in the liver is described. The hallmark of severe (grade III) damage is centrizonal necro... | 826,016 | [
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Sensitivity test on Neisseria meningitidis strains to antimicrobial drugs. | 1. The Authors present the antibiotic sensitivity pattern of 62 Neisseria meningitidis strains isolated in Northern Ghana (Bawku, Navrongo, Bolgatanga and Nalerigu) in February-March, 1973. The following antibiotics or chemotherapeutic drugs were effective in vitro: Penicillin 100%, Ampicillin 100%, Chloramphenicol 100... | 826,042 | [
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Multiple drug resistance in Klebsiella-Enterobacter, Proteus mirabilis and Pseudomonas aeruginosa--an analysis of all-nation computer-processed data. | This last communication on the results of an one-year computer follow-up of single, double, and multiple antibiotic resistance of so-called problem bacteria in Slovakia presents computerised data on double, and important triple, quadruple and quintuple resistance of Klebsiella-Enterobacter, P. mirabilis and Ps. aerugin... | 826,047 | [
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Preservation of a N. meningitidis strain by freezing. A model experiment. | By means of a model experiment the possibility of preserving a N. meningitidis strain by freezing was demonstrated and verified. The results of cultivating the strain after storage at - 20 degrees C, - 15 degrees C and +4 degrees C for 4, 6, 24 and 48 hours were compared. The temperature of - 20 degrees C was found to ... | 826,048 | [
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[Illness behavior: design for an empirical study of the determining factors]. | A large gap is existing between the system of medical services and the "consumer". It is necessary to reinforce preventive attitudes and behavior should prepare the fundamental concepts. A research design is presented. | 826,043 | [
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Studies on human platelets stored at 20-22 degrees C without agitation. | Human blood platelets in ACD plasma were stored in sterile plastic bags for 24-96 h at the ambient temperature without agitation. No spontaneous aggregation nor bacterial contamination were noted. A progressive loss of the following parameters was seen: platelet count; ADP-, thrombin-, collagen-, and epinephrine-induce... | 826,071 | [
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The production of urinary phenols by gut bacteria and their possible role in the causation of large bowel cancer. | Epidemiological evidence is presented to relate the amount of dietary meat to the risk of large bowel cancer; it has been suggested that this may be due to the production of cocarcinogenic volatile phenols by intestinal bacteria from tyrosine. This paper describes preliminary experiments to test this suggestion. In vit... | 826,152 | [
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Histological and physiological studies of cyclocryotherapy in primate and human eyes. | In human and primate eyes treated with cyclocryotherapy, the epithelial and capillary elements of the ciliary processes were destroyed and replaced by fibroblast-like cells. The trabecular mesh-work and Schlemm's canal were histologically affected by cyclocryotherapy. Damage to the angle structures impaired aqueous out... | 826,160 | [
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Specific and nonspecific antitumor immunity. III. Specific T lymphocyte-mediated cytolysis of P815 mastocytoma and SL2 lymphoma by draining lymph node cells from syngeneic tumor-bearing DBA/2J mice. | Tumor-specific cytolytic activity, as measured by the 51Cr release assay, has been demonstrated in the draining lymph node cells from DBA/2 mice bearing the syngeneic P815 mastocytoma or SL2 lymphoma. This lytic activity is mediated by cytolytic T lymphocytes (CTL), since cytotoxicity is eliminated by treatment of the ... | 826,167 | [
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Relationship of chromosome changes to neoplastic cell transformation. | Chromosomal abnormalities are a frequent concomitant of neoplasia, and although it is tempting to relate these mutations and alterations in chromatin (DNA) function to cancer, their relationship to the initiation or progression of carcinogenesis is unknown. Mammalian cells in culture, after interacting with chemical ca... | 826,168 | [
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Control of baboon limb blood flow and heart rate-role of skin vs. core temperature. | To discover the relative importance of body core temperature versus bodyskin temperature in raising limb blood flow and heart rate, we exposed seven unanesthetized, chaired baboons (Papio anubis) to a variety of heating protocols. First, the baboons were exposed to a 40-45 degrees C environment for 0.75-1.5 h. Arterial... | 826,175 | [
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Dependence of Cr-EDTA absorption from the rumen on luminal osmotic pressure. | A method for the measurement of [51Cr]EDTA absorption from the ventral sac of the rumen with an error of the order of +/-10% is described. When a solution present in the rumen was hypotonic or isotonic, the absorption rate of [51Cr]EDTA expressed as a clearance was about 0.2 ml/min. This gave rise to negligible errors ... | 826,179 | [
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Immunotherapy of cancer with cell wall skeleton of Myocabacterium bovis-Bacillus Calmette-Guérin: experimental and clinical results. | Adjuvant and antitumor activities of CWS prepared from cells of mycobacteria, nocardia, and corynebacteria were examined. Oil-attached CWS of M. bovis BCG (BCG-CWS) stimulated the generation of cell-mediated cytotoxic effector cells in mice. Tumor growth was suppressed in mice inoculated intradermally with a mixture of... | 826,205 | [
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A barley lectin that binds free amino sugars. I. Purification and characterization. | A lectin was isolated from barley seen which bound the coat glycoprotein of barley stripe mosaic virus (Type strain) and precipitated the virus from solution. Purification of the barley lectin was achieved by fractionation with ammonium sulfate and successive column chromatography on DEAE cellulose and cellulose phosph... | 826,269 | [
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Molecular properties and a nonidentical trimeric structure of purine nucleoside phosphorylase from chicken liver. | Some molecular properties of crystalline purine nucleoside phosphorylase (purine nucleoside: orthophosphate ribosyltransferase, EC 2.4.2.1) from chicken liver were investigated and discussed. The molecular weight of the native enzyme was determined to be 89 000 by gel filtration and sedimentation coefficient, and 90 00... | 826,273 | [
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[Diagnosis of toxoplasmosis by indirect hemagglutination. I. Comparative study of fixation of glutaraldehyde on formolized erythrocytes of a soluble endogenous antigen, and insoluble particulate antigen and a total antigen]. | Three different sorts of antigen are prepared ultrasonically: a soluble endogenous antigen, an insoluble particular antigen and a total mixed antigen. Formolinized red blood cells are sensibilized with glutaraldehyde. The authors study the sensitivity of the suspensions as a function of the different modes of antigen p... | 826,288 | [
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The stability of the electrical stimulation map of the motor cortex of the anesthetized baboon. | We have made repeated maps of the movements obtained by threshold electrical stimulation, with surface cathodal trains of pulses, of the motor cortex of 4 baboons, using chronically implanted arrays of electrodes. The electrode arrays were judged to remain in a constant relationship with the cortex because they did not... | 826,304 | [
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Effects of some commercial preparations of polychlorinated biphenyls in growing piglets. | Sixty-four piglets were given ad libitum commercial rations containing 250 ppm of polychlorinated biphenyls as Aroclor 1232, Aroclor 1242 and Aroclor 1254 for periods up to 12 weeks. The toxic effects of the polychlorinated biphenyls upon plasma testosterone levels, the blood coagulation system, the gross- and micropat... | 826,311 | [
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Mutagenicity of N-alpha-acetoxyethyl-N-ethylnitrosamine and N,N-diethylnitrosamine in relation to the mechanisms of metabolic activation of dialkylnitrosamines. | The mutagenicities of N-alpha-acetoxyethyl-N-ethylnitrosamine and N,N-diethylnitrosamine were compared in Drosophila for an assessment of the role of alpha-carbon ethyl oxidation in the toxicological activation of the amine. The relative genetic potencies of the two compounds were deduced from regression studies of the... | 826,315 | [
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Immunocytochemical demonstration of separate vasotocinergic and mesotocinergic neurons in the amphibian hypothalamic magnocellular neurosecretory system. | Using the unlabeled antibody peroxidase-antiperoxidase (PAP) technique at the light microscopic level, it was demonstrated that, in the amphibian magnocellular hypothalamo-hypophysial neurosecretory system, vasotocin and mesotocin are synthesized in separate neurons. A tendency to preferential location of the two kinds... | 826,319 | [
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[A new approach of the hemodynamics of human essential hypertension. Study of the control of cardiac output]. | The smoothing technique is used in this part II to study the cardiac output control in normotensive and hypertensive subjects. It is proved that: 1. cardiac frequency and total blood volume are both determinants of cardiac output in the normotensives; 2. in the hypertensives, blood volume is the main factor, the role o... | 826,339 | [
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[Demonstration of an endo-beta-N-acetyl-glucosaminidase in rabbit serum]. | An endo-beta-N-acetyl glucosaminidase of rabbit serum has been characterized after purification by affinity chromatography. The specificity was determined by fluorimetric monitoring of the hydrolysis of 4-methylumbelliferyl-beta-glycosides and by thin layer chromatography identification of the hydrolysis products of fl... | 826,351 | [
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[Correction of experimental hyperlactatemia and lactic acidosis by sodium dischloroacetate]. | Sodium dichloroacetate prevents and fights against the severe hyperlactatemia and lactic acidosis induced by phenformin, intense muscular work, hypoxia and by adrenalin perfusion. The beneficent effects of sodium dichloroacetate and insulin are additive. | 826,352 | [
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Studies on the sex-specific lethals of Drosophila melanogaster. II. Further studies on a male-specific lethal gene, maleless. | Effects of a second chromosome male-specific lethal gene, maleless (mle), of Drosophila melanogaster were further studied. It was shown that, although no maternal effect was seen with respect to the male-specific lethality, the lethal stage was influenced by whether parental females were homozygous or heterozygous for ... | 826,446 | [
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Characterization of postreplication repair in mutagen-sensitive strains of Drosophila melanogaster. | Mutants of Drosophila melanogaster, with suspected repair deficiencies, were analyzed for their capacity to repair damage induced by X-rays and UV radiation. Analysis was performed on cell cultures derived from embryos of homozygous mutant shocks. Postreplication repair following UV radiation has been analyzed in mutan... | 826,451 | [
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Orientation disruptor (ord): a recombination-defective and disjunction-defective meiotic mutant in Drosophila melanogaster. | The effects of a semidominant autosomal meiotic mutant, orientation disruptor (symbol: ord), located at 2-103.5 on the genetic map and in region 59B-D of the salivary map, have been examined genetically and cytologically. The results are as follows. (1) Crossing over in homozygous females is reduced to about seven perc... | 826,453 | [
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[Rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie), II: isolation and amino acid sequence of the tyrptic peptides from the H-chain (author's transl)]. | The reduced and carboxymethylated H-chain of protein Nie was digested with trypsin. 40 tryptic peptides were isolated from the digest by ion exchange chromatography, accounting for the entire amino acid composition of the polypeptide chain. Sequence studies performed with these fragments revealed the position of 444 ou... | 826,474 | [
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[The effect of nitroglycerine medication on the arterial oxygen pressure in obstructive lung disease]. | Nitroglycerine gains increasing interest because of its favourable hemodynamic effects in patients with left heart failure, especially in those with coronary heart disease. The drug-induced vasodilatation and lowering of pulmonary arterial pressure, is followed by a redistribution of lung perfusion which occasionally m... | 826,507 | [
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Catalytic mechanism of p-hydroxybenzoate hydroxylase with p-mercaptobenzoate as substrate. | p-Hydroxybenzoate hydroxylase (EC 1.14.13.2) from Pseudomonas fluorescens catalyzes in vivo the hydroxylation of p-hydroxybenzoate by molecular oxygen to form 3,4-dihydroxybenzoate. p-Mercaptobenzoate is also a substrate of the enzyme, but instead of being converted to the expected product, 3-hydroxy-4-mercaptobenzoate... | 826,528 | [
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Anthranilate synthase-amidotransferase (combined). A novel from of antrhanilate synthase from Euglena gracilis. | Anthranilate synthase from Euglena gracilis strain Z was purified to electrophoretic homogeneity. The enzyme migrated as a single symmetrical peak on sucrose density gradients with a sedimentation constant of about 5.0 S. The molecular weight determined by gel filtration on Sephadex G-200 was 80,000 +/- 2,500. Polyacry... | 826,535 | [
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Measurement of 3,3',5'-Triiodothyroinine (reverse T3), 3,3'-L-diiodothyronine, T3 and T4 in human amniotic fluid and in cord and maternal serum. | In order to assess fetal function at term, we have investigated parameters of thyroid hormone secretion and degradation in human amniotic fluid and in cord and maternal sera at delivery. The parameters measured included 3,3' L-diiodothyronine (3,3'T2), 3,3',5'-triiodothyronine (reverse T3), 3,3',5'-triiodothyronine (T3... | 826,545 | [
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Primate pulpal response to ultraviolet light-polymerized direct-bonding material systems. | The results of this study, plus those of a previous study, show that a layer of CaOH lining the floor of the tooth cavity will protect the dental pulp against toxic irritants inherent to an UV light-polymerized cavity liner and a UV light-polymerized composite restorative resin. This study also showed that a layer of C... | 826,551 | [
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Effect of streptomycin on the structure and function of the photoreceptor apparatus of Euglena gracilis. | The progressive modification of the photoreceptor apparatus, induced by addition of streptomycin (SM) to cultures of dark-bleached Euglena, is correlated with the change of the photomotor response. One of the effects of drug-treatment is the reduction of carotenoid synthesis; the total carotenoid content decreases from... | 826,601 | [
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Three dimensional structure of the endochorion in wild type Drosophila melanogaster. | The endochorion of the Drosophila melanogaster eggshell has been isolated and its structure examined by transmission and scanning electron microscopy. In the main shell the thin inner endochorion (floor) shows small pits or pores and characteristic fenestrae crossed by irregular strands; vertical columns surrounded by ... | 826,602 | [
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The attraction of Trypanosoma cruzi to vertebrate cells in vitro. | A video technic is described that permits a quantification of the degree of attraction of Trypanosoma cruzi trypomastigotes to vertebrate cells in vitro. Bovine embryo skeletal muscle cells (BESM), HeLa cells and Vero cells all attract a myotropic strain of T. cruzi trypomastigotes. BESM cells, however, are 2-fold more... | 826,623 | [
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Disseminated intravascular coagulation in rabbits: synergistic activity of meningococcal endotoxin and materials egested from leucocytes containing meningococci. | Leucocyte-egested material was harvested after the quantitative in-vitro phagocytosis of Neisseria meningitidis by rabbit or mouse polymorphonuclear leucocytes. The egested material was injected subcutaneously into rabbits and followed 24 h later with an intravenous injection of what would by itself have been a non-let... | 826,630 | [
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Possible polychlorinated biphenyl poisoning in rhesus monkeys (Macaca mulatta) | In 1967-68 rhesus monkeys that had been held in new pens for a month or more developed a chronic disease with high mortality. The principal postmortem findings were focal necrosis of the liver and hyperplasia of bile duct epithelium, invasive gastric mucosal metaplasia, and squamous metaplasia of the sebaceous glands. ... | 826,638 | [
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Immunofluorescence studies of benign and malignant human mammary tissue. | Indirect immunofluorescence studies on sections of human normal breast tissue, benign breast lesions, and breast adenocarcinomas were performed with the use of monospecific fluorescein-conjugated antisera to human alpha, gamma, and mu chains, albumin, and C3. In all tissues, benign and malignant, immunohistologic local... | 826,647 | [
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Chemical carcinogen-induced transplantable fibrosarcomas in histocompatible chickens. I. Incidence of tumor induction in normal and bursectomized chickens. | Transplantable fibrosarcomas were developed in two B-locus-defined chicken strains from primary tumors induced by im injection of 2 mg 7,12-dimethylbenz[a]anthracene in 0.1 ml dimethyl sulfoxide into 1- to 2-week-old chicks. Viruses were not important factors in transmission of these tumors as evidenced by 1) transplan... | 826,648 | [
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Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias. | BALB/cCrgl, C57BL/Ki, and (C57BL/Ki X DBAf)F1 mice were treated with 7,12-diemthylbenz[a]anthracene (DMBA) or urethan to determine conditions that would induce a high frequency of ductal hyperplasias in the mammary gland. Among virgin BALB/c mice treated with either 3.0 or 4.0 mg DMBA, ductal hyperplasias and mammary t... | 826,649 | [
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Combined-modality oncotherapy with cyclophosphamide (NSC-26271) and radiotherapy: control of murine mastocytoma. | We investigated the effects of cyclophosphamide, alone and in combination with a 1,000-R/week radiotherapy schedule, on the growth of solid P815X2 tumors in 12-week-old male DBA/2 mice. Single-dose treatments of 150 mg cyclophosphamide/kg were given to animals bearing tumors of different ages. Such treatment of young t... | 826,650 | [
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L-asparaginase-antileukemia agent. | This paper is an extension of a previous report (Yaqub 1975). Our interest in L-asparaginase is increasing due to the recognition of the fact that it is a best tool against leukemia. In this paper we have tried to discuss (in view of research work, 1973-75) its basic characteristics and its practicability of successful... | 826,661 | [
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Growth of measles virus in nervous tissues. IV. Neurovirulence of wild measles and SSPE viruses in monkeys. | Neurovirulence of in vivo-passed wild measles virus and that of the cell-associated SSPE virus were compared by intracerebral inoculation into monkeys. The wild measles virus was found to lack neutrovirulence without producing neurological signs or significant histological changes in the brains, whereas the virus was c... | 826,674 | [
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[Hypoplasia of the pulmonary artery in Rieger's Syndrome (author's transl)]. | A 7-year-old child with Rieger's syndrome was reported in whom hypoplasia of the peripheral branch of the pulmonary artery was diagnosed via cineangiocardiography. | 826,736 | [
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[The effects of the weather on hemophilic hemarthrosis (author's transl)]. | Hemophilic hemarthroses occur more frequently in spring and autumn. In the present study, possible weather situations are investigated which are characterized by a particular action on the increasing of hemorrhagic tendency. In 574 hemarthroses in 45 patients, the regional weather events were set in relation to the hem... | 826,793 | [
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[Parathyroid adenoma from the surgical view point. Report of 65 cases]. | Experience in the surgical management of a series of 65 cases with hyperparathyroidism is described (primary HPT: 55, secondary HPT: 3, tertiary HPT: 2, malignant HPT: 5) The consecutive forms of primary HPT, i.e. quarternary or quinternary HPT, and of secondary HPT, i.e. tertiary HPT, are discussed in more detail. Dys... | 826,794 | [
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[Tick-borne meningopolyneuritis (Garin-Bujadoux, Bannwarth)]. | The meningopolyneuritis first described in 1922 by Garin and Bujadoux develops after a tick bite. At the site of the bite in some of the cases, erythema chronicum migrans develops first. Severe pains follow in this area which may spread to other parts of the body. Then peripheral paralysis appears with asymmetrical dis... | 826,813 | [
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[Motoricity in the aging human (author's transl)]. | Every period of human life is accompanied by its own motoricity. Apart from spastic, extrapyramidal and cerebellar disturbances resulting from various types of diseases of middle and old age, the individual associated movements in miming and gesture become unharmonious and stiffer with increasing age and the hyperkines... | 826,819 | [
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0.4547563,
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The effect of caffeine on repair systems in oocytes of Drosophila melanogaster. III. Genetic analysis of factors controlling maternal repair in a repair-deficient strain of Drosophila melanogaster. | Genetic analysis was performed to locate the factors involved in the defective repair mechanism in the oocytes of Ubx e4/Payne ca females. The results demonstrate that at least three third-chromosome factors may be involved in the control of maternal repair, the two most effective ones being located on the right arm of... | 826,823 | [
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Experimental observations on the effect of amphepramone on the behavior, locomotion, pentretrazol seizures and electroencephalogram. | Amphepramone, an anorectic agent, has been found to possess stimulant properties on the C.N.S. in animals, producing hypermotility and stereotyped movements which can be antagonized with neuroleptics. The stimulant activity of amphepramone observed in animals can be correlated with the amphetamine like psychosis observ... | 826,957 | [
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0.1602038,
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0.1489246,
0.1381578,
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Effects of chronic d-amphetamine on social behavior of the rat: implications for an animal model of paranoid schizophrenia. | Hooded rats in a social colony were given increasing daily doses of d-amphetamine up to 8 mg/kg. Time-lapse 16 mm cinematographically recorded behavior was analyzed for the following: grooming, feeding, sex, sleeping, resting, sterotypy, agonistic behavior, muricidal activity, and the location and movement of each rat.... | 826,965 | [
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0.08368... |
Comparison of behavior maintained by infusions of eight phenylethylamines in baboons. | Doses of eight phenylethylamines were substituted for cocaine on a drug-maintained behavior baseline in baboons. Intravenous infusions of drug were contingent upon completion of 160 lever presses (a 160-response fixed-ratio schedule; FR 160). A 3-h time-out period followed each infusion, permitting a maximum of 8 infus... | 826,970 | [
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[A device for the evaluation of motor incorrdination in rats (author's transl)]. | A runway apparatus for rats has been developed for measuring motor incoordination and running time. Animals were trained to run along an elevated narrow pathway. Frequency and severity of slipping off and running time were automatically counted. Rats were given diazepam, phenobarbital or chlorpromazine orally and teste... | 826,974 | [
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Piperidine: effects on locomotor activity and brain monoamine turnover. | The effects of piperidine HCl (PHCl) on locomotor activity, flexor reflex activity and monoamine levels, turnover, and synthesis were studied. Results indicate a sedative action and an increased turnover of noradrenaline (NA), but no effects on 5-hydroxytryptamine (5-HT) or dopamine (DA). Data obtained from flexor refl... | 826,977 | [
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[Regulation of citrate synthese in bacteria: Comparison of the action of various effectors on the enzymes of Rhodospirillum rurbum and Bacillus stearothermophilus]. | A comparative study of the citrate synthases purified from the facultatively photosynthetic bacterium Rhodospirillum rubrum (Gram negative) and the thermophile Bacillus stearothermophilus (Gram positive) was made. The citrate synthase from R. rubrum was activated by KCl (6-fold at 0.1 M KCl) and, less effectively, by N... | 826,987 | [
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Antibody suppression and antiallotype antibodies. II. Interference of circulating antiallotype antibodies with prophylactic treatment against Rh sensitization. | Sera from Rh-sensitized women representing presumable failure of the prophylactic treatment with IgG anti-D (Rh) have been examined for activity against allotype markers on IgG1. Antiallotype antibodies were found with increased frequency compared with a nonsensitized control. In general, however, interference of antia... | 827,012 | [
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... |
[Amnesia syndrome due to tumor infiltration]. | The authors present their anatomo-clinical observation of amnesic syndrome occurring with brain tumoral infiltration. On the clinical level, the disorder is characterized by a memory encoding deficit. Anatomical examination shows a bilateral lesion of the mamillary bodies. | 827,016 | [
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... |
Cost-benefit analysis of synovectomy of the knee. | The subject of this study was the cost-benefit ratio of synovectomy of the knee. Synovectomy of the knee is the most common operation at the Rheumatism Foundation Hospital, Heinola. In 1973 it accounted for 8.8% of all orthopedic operations performed. The survey material comprises 225 synovectomies of the knee performe... | 827,018 | [
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... |
A new method for detection and localization of urinary infection. The fluorescence antibody test. | The urinary sediment of 56 patients with active urinary infection were studied through a direct immunofluorescence technique in order to detect the presence of antibody-coated bacteria. In 35-36 pyelonephritis cases the results were positive. However, in 11 cases with lower urinary infection there was no sign of antibo... | 827,041 | [
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0... |
[Effectiveness of Nilzan and Dovenix in the treatment of fascioliasis in cattle and sheep]. | The authors tested the effectivity of the foreign preparations Nilzan (tetramisole ++ oxyclozanide) and Dovenix (nitroxynil) in the treatment of cattle and sheep naturally invaded by Fasciola hepatica. The effectiveness of the two preparations was evaluated on the basis of the results of coprological examination in the... | 827,048 | [
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0.2564367,
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[Aetiology of dupuytren's contracture (author's transl)]. | Regarding experimental data on the multi-factorial reduction of the thermostability of collagen, the following sequence of the mechanism of Dupuytren's contracture is discussed: 1. Hereditary or acquired weakness of fibres of the palmar fascia 2. Further disturbance of the physical property of collagen by the cumulativ... | 827,084 | [
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Cellular reactions to small cerebral stab wounds in the rat frontal lobe. An ultrastructural study. | Small stab wounds were made in the frontal lobe of adult rats by the insertion of a glass capillary or a steel needle with a diameter of 50 mum. Macroscopically, there was a minute lesion filled with red blood cells. Ultrastructurally, there was a prominent edema with 200 mum from the wound during the first 3 days. The... | 827,093 | [
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Increase of mitosis in the tubular epithelium following intrarenal doses of various kidney homogenates and hemogenate fractions in the rat. | Earlier investigations about the consequences of experimental kidney ischemia raised the question, if there exists a substance in the renal tissue which is liberated by cell death or during regeneration of cells and which might stimulate mitosis of other cells. Therefore in recent experiments we directly injected into ... | 827,095 | [
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Effects of transient hypotension on the structure and function of rat kidney. | The immediate effects of renal structure and function of 60 or 90 min of hypotension and the effects of one to four days of recovery were studied in the rat. An initial diuresis occurred during the first day after hypotension, followed by decreased urine volumes. Along with the diuresis, the animals secreted a hypo-osm... | 827,098 | [
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[Metabolism of 7,12-dimethylbenz(alpha)anthracene in vivo]. | The metabolism of 7,12-dimethylbenz(alpha) anthracene (DMBA) was studied, using labelled DMBA-H3, after intravenous injection of the carcinogen in female animals. The maximum excretion of the metabolites took place during the period ranging from 6 to 24 hours. The content of liposoluble metabolites in the urine was ins... | 827,119 | [
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Monoclonal plasma cell population in the uterus. | The case of a 28-year-old female patient is presented. Heavy infiltration with plasma cells of uterine tissue removed by surgical currettage following an aborted pregnancy was detected by cytological and histological examination. Subsequent immunohistochemical studies revealed the monoclonal nature of these cells: intr... | 827,133 | [
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Nitrogen-sparing effect of fat emulsion compared with glucose in the postoperative period. | The investigation was directed towards elucidating two questions of current interest in parenteral nutrition: (1) Is it at all possible to obtain positive nitrogen balance during the immediate postoperative course (the "catabolic phase")? (2) Is there any difference in the nitrogen balance if the main energy source con... | 827,173 | [
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A comparative numerical study of the trigeminal mesencephalic nucleus. | A comparative statistical study of the trigeminal mesencephalic nucleus in 30 cats, 10 rats, 2 monkeys and 2 slow lorises has been presented. In contrast to previous results which show great discrepancies in neuronal counts in all species, and even in individuals of the same species, uniformity of estimates has been ac... | 827,187 | [
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[Globoid cells leukodystrophy apropos of a case of Krabbe's disease]. | A case of Krabbe's leucodystrophy is reported after photon and delayed ultrastructural microscopic study. Cerebroside overload within the cerebral globoid cells was shown as well as in the interstitial histiocytic infiltration of the peripheral nerves. Reviewed with the published literature, the characteristics of the ... | 827,220 | [
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Heme catabolism by the reconstituted heme oxygenase system. | The heme oxygenase system was reconstituted from heme oxygenase purified from pig spleen microsomes and NADPH-cytochrome c reductase purified from pig liver microsomes. The pig spleen heme oxygenase does not appear to involve cytochrome P-450 but seems to be a protein which readily binds heme to form a heme-protein com... | 827,230 | [
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... |
Secretory IgA in protein-calorie malnutrition. | The secretory IgA system was investigated in children with protein-calorie malnutrition (PCM). The results of the study indicated that in children suffering from kwashiorkor and marasmus the concentration of IgA in duodenal fluid, saliva, nasal secretions, and tears was significantly reduced on admission and returned t... | 827,242 | [
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... |
[Epicardial scintigraphy in 4 cases of ventricular tachycardia caused by reentry of blood after myocardial infarct. Study of intra-ventricular conduction disorders in sinus rhythm and in tachycardia, and their relations to anatomical data]. | Ventricular pericardial cartography in sinus rhythm (SR) and during ventricular tachycardia (VT) in four cases of myocardial infarction has yielded additional information in the study of conduction disorders in myocardial ischaemia: 1. The significant slowing of activity in SR as well as in VT is demonstrated by this d... | 827,248 | [
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... |
[Occurrence of cytotoxic anti-HL-A antibodies in female patients sensitized to Rh antigens]. | The frequency of sentization to HL-A system antigens in the categories of Rh-sentized patients was studied, considering the observation that in this category the precentage of senzitization to the system of transplantation antigens is much higher than in other groups. A total of 211 samples of sera of Rh-sensitized pat... | 827,282 | [
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Biology of a duplicate gene system with glucose 6-phosphate dehydrogenase activity in Drosophila melanogaster: genetic analysis and differences in fitness components and reaction to environmental parameters among Zw genotypes. | There are two structural forms of glucose 6-phosphate dehydrogenase activity in Drosophila melanogaster. Whether one or the other or both show in vitro (and probably in vivo) activity depends on the genotype of a sex-linked locus (Zw). In this article, the relative fittnesses of heterozygotes (with both electromorphs a... | 827,285 | [
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Trypsin-induced phospholipase activity in human platelets. | Trypsin mediates a release of arachidonic acid with resultant increase in O2 consumption (a reflection of cyclo-oxygenase activity) by whole human platelets that is similar to thrombin's effect on these cells. The trypsin and thrombin effects can be differentiated in two ways: (1) at saturating concentrations the measu... | 827,290 | [
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[Example of the use of affinity electrophoresis for the determiniation of antigens]. | In this paper, affinity electrophoresis is employed to obtain a quantitative evaluation of an antigen using biospecific immunoadsorbant. As an example it is shown that human serum albumin reacts with its specific antibodies linked to agarose beads forming "rockets" in the gel. The height of these "rockets" corresponds ... | 827,366 | [
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0.02927644,
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[Occurrence of hyperuricemia in atrioventricular block. (Results of a study of 158 patients with isotopic pacemaker implantations)]. | The frequency of hyperuricemia is high in these patients with heart block, whose mean age is 39. 91% have serum uric acid levels above the normal range and 61% present "hyperuricemia," according to "gouty risk" criteria. The mean uric acid level, before surgery, of the patients whose total heart block follows "open-hea... | 827,367 | [
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-0.2753761,
... |
[Inhibition of thalamic activity by stimulation of the inferior raphe nucleus in the chronically awake cat]. | Poly U dependent polyphenylalanine synthesis from 14C phenylalanyl-tRNA, under known optimal conditions, in ribosomes obtained from NaF-treated Rabbit reticulocytes, is only slightly stimulated by the addition of ATP, GTP and UTP in the absence of phosphoenolpyruvate and pyruvate kinase. However, in the presence of the... | 827,374 | [
0.1854289,
-0.1498871,
0.1450446,
0.03764056,
0.5133722,
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0.1077779,
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0.09134104,
0.1396487,
0.2610062,
0.1939224,
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-0.01045936,
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0.3942655,
0.193653,
-0.03063215,
-0.1711318,
... |
[Melanotropic hormone in the green frog (Rana esculenta): biochemical and radioimmunological study]. | The alpha-MSH levels in the frog hypophysis were measured by use of a sensitive ans specific radioimmunoassay. Sephadex G-50 gel chromatography of frog pars distalis and pars intermedia extracts showed that frog hypophyseal MSH was chemically related to synthetic alpha-MSH. Rat tissue homogenates were capable of degrad... | 827,375 | [
0.1394835,
-0.4654837,
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0.2115173,
0.04853143,
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-0.4757292,
0.01993452,
0.1093986,
0.01762405,
0.2192985,
0.1686646,
0.2371173,
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0.4512082,
0.3467012,
0.1469204,
0.4632297,
-0.2183514,
-0.4281399,
-0.26... |
[Autoradiographic study of ribosomal RNA metabolism during mitosis in the myxomycete Physarum polycephalum]. | In Physarum polycephalum, the study of RNA metabolism just after metaphasis shows an important 3H-uridine incorporation. Most of the labelling is found in the nucleolus when we can see it again during interphasis. Therefore a ribosomal RNA synthesis does exist before any visible nucleolar structure. | 827,386 | [
-0.1762473,
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0.2588049,
0.06697412,
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0.1309728,
0.1456893,
0.03543146,
0.1385117,
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0.04782863,
0.04683407,
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0.8898453,
0.06368186,
-0.100196... |
[New approach to the hemodynamics of human essential hypertension. Study of mean values]. | A method of data analysis is proposed. Applied to the essential human hypertension study, the method put into evidence broken points in the evolution of certain hemodynamic parameters. These results could not be obtained by classical statistical analysis. | 827,392 | [
-0.1247801,
0.0746149,
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0.07112961,
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0.5082269,
0.05629634,
0.1211516,
-0.1083014,
0.2... |
Effect of a large dose of thyrotrophin releasing factor on pituitary and thyroid function in patients with Parkinsonism. | Thyrotrophin releasing factor (TRF) was given intravenously in doses of 0-5 mg and 20 mg to six patients with Parkinsonism treated with L-dopa. Plasma thyrotrophin (TSH), prolactin, lutenizing hormone (LH), follicle stimulating hormone (FSH), thyroxine (T4) and triiodothyronine (T3) were measured before and after TRF i... | 827,396 | [
0.05301226,
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0.2690385,
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0.2840538,
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0.1951001,
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-0.0384489,
-0.09769678,
0.2569908,
-0.08194537,
0.3272433,
-0.0383... |
Transplacental gradients of sex-hormone-binding globulin in human and simian pregnancy. | An attempt has been made to clarify the degree and control of production of the concentration gradient of sex-hormone-binding globulin (SHBG) between human mother and fetus. SHBG was measured by an improved ammonium sulphate precipitation method using 5 alpha-dihydrotestosterone as ligand. Maternal and fetal (cord bloo... | 827,397 | [
-0.002594944,
0.1563815,
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-0.09157851,
0.2882966,
0.4471376,
-0.09710066... |
The functional significance of certain duplicate motor patterns on the cerebral cortex in primates including man. | Rotation elicitable from direct irritation or implantation of the cortical irritant, penicillin, in both rostral and posterior parts of the temporal operculum and on the island cortex in the monkey (Macaca mulatta) has been described and illustrated in photographs. The pathways to and from these temporal and island are... | 827,407 | [
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0.1001968,
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0.09381831,
0.2583556,
0.1273323,
0.10995... |
The binding site of protein L1 on 23-S ribosomal RNA of Escherichia coli. 1. Isolation and characterization. | Ribonucleoproteins were prepared by ribonuclease digestion of a reconstitued complex of ribosomal protein L 1 and 23-S RNA from Escherichia coli. Three main ribonucleoproteins were identified. The largest was only obtained in an impure state at low ribonuclease concentration, whereas the two smaller ones, which were di... | 827,438 | [
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0.09161255,
0.08003625,
0.4255016,
0.02056437,
-0.186083,
... |
The binding site of protein L1 ON 23-S ribosomal RNA of Escherichia coli. 2. Identification of the rna region contained in the L1 ribonucleoproteins and determination of the order of the RNA subfragments within this region. | Ribonucleoproteins were obtained by T1 ribonuclease digestion of reconstitued complexes of ribosomal protein L1 AND 23-S RNA from Escherichia coli. The RNA region of the main ribonucleoprotein 2 was totally digested with T1 ribonuclease. The oligonucleotide products were characterised and they showed that this region c... | 827,439 | [
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0.5156405,
0.3486389,
-0.3162131,... |
RNA sequences associated with proteins L1, L9, and L5, L18, L25, in ribonucleoprotein fragments isolated from the 50-S subunit of Escherichia coli ribosomes. | 32P-labelled 50-S subunits from Escherichia coli ribosomes were hydrolysed under conditions known to give rise to two specific ribonucleoprotein fragments, containing proteins L1, L9, and L5, L18 and L25 respectively. RNA corresponding to these ribonucleoproteins was isolated and purified, and the various RNA fragments... | 827,440 | [
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0.03479023,
0.1117958,
0.4667578,
0.1784072,
-0.2112... |
Hematological development of the infant squirrel monkey (Saimiri sciureus). | Hematologic developmental norms from infant squirrel monkeys indicate a relative maturation of the hematopoietic system by 16 weeks. The elevated hemoglobin, hematocrit, red blood cell count, MCV and MCH at birth are followed by a decreasing hemoglobin (decreasing red blood cell count and MCV) until 4 weeks of age. A r... | 827,482 | [
0.1085117,
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0.1632793,
0.3415103,
0.2311704,
0.07626504,
0.2104652,
-0.07559102,
-... |
Genetical distance and dermatoglyphic characters. I. Interpopulation distance coefficients. | The distance coefficients between two relatively isolated population groups in Poland, based on various combinations of dermatoglyphic non-measurable characters were estimated. These were compared with the overall dermatoglyphic distance coefficients estimated separately for left and right, as well as with the serologi... | 827,486 | [
0.008272301,
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0.3517897,
0.3061685,
0.3810293,
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0.06102621,
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0.2882794,
0.08887,
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0.2106872,
0.1140633,
-0.02213402,
0.3995105,
0.2213131,
-0.2057699,
... |
Production and isolation of cerexins C and D studies on antibiotics from the genus Bacillus. XVII. | From the culture broth of Bacillus cereus 60-6, in which antibiotic production was improved a new antibiotic, named cerexin C, was isolated. Similarly, a new antibiotic, cerexin D was isolated from the culture broth of Bacillus cereus Gp-3. Cerexins C and D are closely related to cerexins A and B in their physico-chemi... | 827,541 | [
0.02004909,
0.05601372,
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0.3214772,
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0.3461315,
0.1122428,
0.06028114,
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0.2111339,
-0.002695701,
-0.1679323,
0.4686687,
0.2014103,
-0.09919371... |
[Mechanism of methane oxidation by intact cells of obligate methylotrophs]. | Ethane and propane were found to be competitive inhibitors of methane oxidation. Obligate methylotrophs can oxidize ethane only in the presence of methane, i.e. co-oxidation of ethane takes place. Studies on the kinetics of simultaneous oxidation of ethane and methane have shown that their oxidation is catalysed by one... | 827,668 | [
-0.3329121,
-0.01298959,
0.07926273,
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0.0680373,
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0.1491605,
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0.3213101,
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-0.6302547,
0.3482587,
0.005237442,
0.337923,
0.1770506,
0.04504205,
-0.0570... |
The properties of hybrids formed between the P-group plasmid RP1 and various plasmids from Pseudomonas aeruginosa. | R38, R931-1, and R933 are conjugative plasmids derived from strains of Pseudomonas aeruginosa. They confer resistance to mercuric ions (Hg-r), and do not tranfer from P. aeruginosa to Escherichia coli at detectable frequencies. Hybrids between each of these plasmids and the P-group plasmid, RP1, have been detected amon... | 827,687 | [
0.09087174,
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-0.4722795,
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0.1520096,
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0.05146671,
0.5056629,
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0.2186425,
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-0.007354558,
0.3339502,
0.3439732,
0.1458534,
0.1449806,
0.05384355,
-0.3089463... |
Skull growth from birth to adulthood in Gilbertese on Betio. | The growth of the skull from birth till adulthood was studied among Gilbertese from Betio. With few exceptions the average head circumference was bigger in males than in females, but rarely at statistically significant levels. After the age of six months the mean head circumference of the Gilbertese fell almost invaria... | 827,720 | [
0.1114164,
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0.01143049,
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0.0001481002,
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0.1683787,
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0.03566467,
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0.04292683,
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0.2381522,
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0.08134578,
0.430069,
-0.06036962,... |
The syndrome of accelerated bone maturation in the newborn infant with dysmorphism and congenital malformations. (The so-called Marshall-Smith syndrome). | A new case of the syndrome of "accelerated skeletal maturation, facial dysmorphism, failure to thrive and psychomotor retardation" is presented. The syndrome was noted in the neonatal period. The diagnosis can be readily suggested by the radiologist because ossification centers show exceptionally early maturation. This... | 827,733 | [
-0.3418258,
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0.2016486,
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0.3481378,
-0.1687318,
-0.3148699,
... |
The effects of haloperidol upon temporal information processing by patients with Tourette's syndrome. | Tourette's syndrome patients treated successfully with haloperidol, untreated patients, and healthy controls were studied with tests of temporal discrimination and measures of transmitted information shown previously to be sensitive to brain dysfunction. Untreated patients showed no impairment of temporal processing wh... | 827,765 | [
-0.03685108,
0.1001167,
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0.1241022,
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0.1183322,
0.1159005,
0.2499035,
0.06602732,
... |
Factors influencing the early plasma disappearance rate and liver uptake of thyroxine. | The early disappearance from plasma (T 1/2) of i.v. administered thyroxine (T4) labelled with 131I was studied in order to find a simple biochemical parameter with which it could be correlated in health and disease. The radioactivity of the liver was also measured by surface counting to determine the time for the peak ... | 827,838 | [
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0.09213988,
0.1384029,
0.3126253,
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0.02334003,
0.3482879,
0.2203479,
0.1772556,
0.5115898,
-0.08428518,
-0... |
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