title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The effect of indomethacin blockade of prostaglandin synthesis on blood pressure of normal rabbits and rabbits with renovascular hypertension. | Indomethacin inhibits the synthesis of prostaglandin and the release of renin. These effects were studied in normal rabbits and rabbits with two-kidney Goldblatt hypertension (2KGH) and one-kidney Goldblatt hypertension (1KGH) by giving daily intravenous injections of indomethacin (3mg/kg after two initial doses of 9 m... | 830,437 | [
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Paradoxical dynamic interaction of heart period and vagal activity on atrioventricular conduction in the dog. | The dynamic interaction of simultaneously changing heart period and single vagal stimuli on atrioventricular conduction (AV interval) was quantified by subtracting the vagally induced responses of the paced heart preparation from those of the unpaced heart preparation. This difference was significantly greater (P less ... | 830,440 | [
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Lower airway foreign body aspiration in children. An analysis of 13 cases. | This analysis of thirteen cases of lower airway foreign body aspiration in children reveals a high incidence of aspiration into the left main bronchus, and an increased incidence in older children. Early indentification of nonradio opaque foreign bodies such as food and plastic toys is difficult in the absence of a pos... | 830,455 | [
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Campylobacter fetus associated with pulmonary abscess and empyema. | An unusual case of community-acquired necrotizing aspiration pneumonia with pulmonary abscess and empyema associated with Campylobacter fetus (formerly Vibrio fetus) in mixed culture is reported. This microaerophilic gram-negative curved bacillus has been increasingly associated with human disease. Unlike most pathogen... | 830,489 | [
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Effects of experimentally-induced chronic hyperprolactinemia on testosterone and gonadotropin levels in male rats and mice. | We have examined testicular and pituitary function in inbred CD-F rats and DBA/2J mice with chronic hyperprolactinemia induced by grafting 4 anterior pituitaries from adult females of the same strain under the kidney capsule. Eight rats were given pituitary isografts and 9 were sham-operated; blood samples were collect... | 830,537 | [
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The culture of pig oocytes in minimal medium, and the influence of progesterone and estradiol-17beta on meiotic maturation. | Pig oocytes, with (intact) or without (denuded) adhering granulosa cells, were cultured for 33 to 35 h in minimal culture media containing bovine serum albumin and either progesterone or estradiol-17beta or both steroids. The incidence of maturation for intact oocytes in minimal medium was comparable, if not superior, ... | 830,545 | [
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The need for comparative pharmacologists in industrial and academic research. | Comparative pharmacologists solidly trained in the principles of modern pharmacology, comparative biology, and comparative medicine are needed in various facets of drug research. Although this type of training would ideally be obtained in the professional medical environment of a veterinary college, the discipline of p... | 830,553 | [
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Undergraduate pharmacological training programs applicable to agricultural science majors. | Undergraduate training programs leading to degrees in pharmacology or toxicology do not exist on most university campuses. Agricultural science students who may ultimately use large quantities of herbicides, pesticides, and other agricultural products may obtain degrees without any exposure to the disciplines of pharma... | 830,554 | [
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Evaluation of diabetes patient-education programs. | Patient education is generally regarded as an essential component of the clinical management of diabetes. However, analysis of the role of patient education in diabetes control has been limited. Formal patient teaching programs at several medical centers range in operation from merely providing knowledge about diabetes... | 830,566 | [
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Hypoglycemia secondary to metastases to the liver. A case report and review of the literature. | A 76-year-old man presented with hypoglycemic coma associated with metastatic liver disease. Serum immunoreactive insulin excluded insulinoma as a cause of hypoglycemia. Negative glucose responses to glucagon and epinephrine testing indicated failure of compensatory glycogenolysis. The patient's increased glucose requi... | 830,586 | [
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The effect of increased crypt cell proliferation on the activity and subcellular localization of esterases and alkaline phosphatase in the rat small intestine. | The activity and ultrastructural localization of alkaline phosphatase and esterase has been studied in normal rat intestine and after the increased crypt cell proliferation that occurs during recovery after 400 rad X-irradiation. Alkaline phosphatase activity is not present in crypt cells of normal intestine, but becom... | 830,626 | [
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Isolation and preliminary characterization of auxotrophic and morphological mutants of the yeastlike form of Paracoccidioides brasiliensis. | N-methyl-N'-nitro-N-nitrosoguanidine, which is known to be a very effective mutagen in many systems, was used to induce mutants in the yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9, an imperfect fungus. Forty-three auxotrophic and 27 prototrophic morphological mutants were isolated after treatment wit... | 830,638 | [
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Isolation and characterization of a plasmid involved with enterotoxin B production in Staphylococcus aureus. | Genetic analysis and molecular characterization of plasmid deoxyribonucleic acid (DNA) was performed in a toxigenic isolate of Staphylococcus aureus strain DU4916. Elimination, transduction, and transformation experiments provided us with a series of derivatives similar except for the presence or absence of genes media... | 830,641 | [
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Membrane differentiations at sites specialized for cell fusion. | Fusion of plasma membranes between Chlamydomonas reinhardtii gametes has been studied by freeze-fracture electron microscopy of unfixed cells. The putative site of cell fusion developes during gametic differentiation and is recognized in thin sections of unmated gametes as a plaque of dense material subjacent to a sect... | 830,653 | [
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Temperature-sensitive mutations affecting flagellar assembly and function in Chlamydomonas reinhardtii. | A series of conditional mutants of the algal, biflagellate Chlamydomonas reinhardtii with temperature-sensitive defects in flagellar assembly and function were isolated. The genetics and phenotypes of 21 mutants displaying a rapid alteration in flagellar function upon shift from the permissive (20 degrees C) to the res... | 830,657 | [
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Effect of exercise on perfusion of collateral-dependent myocardium in dogs with chronic coronary artery occlusion. | Since the ability of mature intercoronary collateral channels to increase myocardial blood flow in response to drug-induced coronary vasodilation has been questioned, the present study was undertaken to evaluate the response of coronary collateral circulation to the stress of exercise. Studies were performed at rest an... | 830,658 | [
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Effects of low-level x-irradiation on cat cerebella at different postnatal intervals. II. Changes in Purkinje cell morphology. | The whole-head of infant kittens was irradiated with fractionated doses of 150 R and 200 R at different postnatal intervals. Experimental age conditions consisted of an irradiated newborn, 1-week, 2-week, 3-week, and a 4-week age condition while the age of sacrifice remained constant at 70 days. The molecular layer thi... | 830,670 | [
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A quantitative study of retrograde neuronal changes in Clarke's column. | A quantitative study has been made of the retrograde neuronal changes that occlr in the large neurons of Clarke's column in the L3 spinal segment, 100 days after dorsolateral column lesions at the medullary, C5, T1, T8, and L1 levels in a series of 10-week-old kittens. Cell counts, and nuclear and perikaryal areal meas... | 830,672 | [
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Passive transfer of systemic tumor immunity with cells generated in vitro by a secondary immune response to a syngeneic rat gross virus-induced lymphoma. | Spleen cells taken from W/Fu rats 4 to 6 weeks after immunization with the syngeneic Gross virus-induced lymphoma, (C58NT)D cells, at a time when they lack detectable activity in a short-term 51Cr release assay, were previously shown to retain the capacity to generate cytotoxic activity upon reexposure to mitomycin C-t... | 830,744 | [
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F1 resistance to AKR lymphoma cells in vivo and in vitro. | AKR X DBA/2 (AKD2F1) mice resist growth of injected spontaneous AKR lymphoma cells. In vitro, normal F1 responder cells generate Thy-1 positive effector cells specifically cytotoxic for the sensitizing antigens of parental AKR normal or lymphoma cells. The possibility is considered that the homozygous normal and neopla... | 830,755 | [
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Thermography of the nose and ear in relation to the skin lesions of lepromatous leprosy, tuberculosis, leishmaniasis, and lupus pernio. | The nasal and aural temperature patterns of 100 normal subjects have been investigated by infrared thermography, paying particular attention to possible errors of instrumentation and technique which may arise in such areas of complex morphology. Although by no means invariable, the pattern of themograms confirms that c... | 830,767 | [
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Studies in porphyria. VI. Biosynthesis of porphyrins in mammalian skin and in the skin of porphyric patients. | Porphyrin biosynthesis in mammalian skin and in skin obtained from patients with selected types of porphyria has been studied. Cutaneous porphyrinogenesis required the precursor delta-aminolevulinic acid (ALA) which, when added to murine, rat, and human skin in vitro, was rapidly converted to porphyrins. Total porphyri... | 830,770 | [
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Activation of complement components C3 and factor B in synovial fluids. | Synovial fluids from 106 patients with various types of arthritis were examined for the presence of conversion products of C3 by means of crossed antigen-antibody electrophoresis and for products of factor B by immunoelectrophoresis. C3 conversion was found in all 15 fluids from patients with seropositive rheumatoid ar... | 830,776 | [
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Efficacy of cryohypophysectomy in the treatment of acromegaly. Evaluation of 54 cases. | Between 1963 and 1974, 54 patients with acromegaly (28 men and 26 women) ranging in age from 23 to 61 years were evaluated. Each patient underwent thorough preperative neurological, roentgenographic, and endocrinological surveys; most demonstrated mild-to-severe abnormalities in growth hormone immunoassay and oral gluc... | 830,806 | [
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Cavernous sinus syndrome produced by communication between the external carotid artery and cavernous sinus. | The authors present two cases of cavernous sinus syndrome with spontaneous onset secondary to arteriovenous malformations and review the cases reported previously. These malformations enlarge slowly and produce symptoms only in adult life. Diagnosis may be difficult when there is no associated bruit. Adequate evaluatio... | 830,819 | [
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Use of 99mTc-Cu-DTPA complex as a renal function agent. | The use of cuprous ion as a reducing agent for pertechnetate is described for the first time. The potential usefulness of a 99mTc-Cu-DTPA complex as a renal function agent was evaluated by organ distribution studies in animals and by simultaneous continuous-infusion and single-injection clearance studies. Radioiodinate... | 830,831 | [
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A radioiodinated bretylium analog as a potential agent for scanning the adrenal medulla. | Studies with radioiodinated bretylium analogs (RIBA) suggested that the p-isomer was capable of concentrating in adrenal medulla. The present studies with 125I-p-RIBA in rats and dogs confirm this property and show its marked and persistent affinity for the adrenal medulla. Analogous studies with 14C-p-IBA indicate tha... | 830,836 | [
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Bile acid malabsorption--a consequence of terminal ileal dysfunction in protracted diarrhea of infancy. | Fecal excretion of labeled bile acid (14C-24-cholic acid) was distinctly increased in two infants with protracted diarrhea, whereas four patients with steatorrhea due to pancreatic or mucosal abnormalities and five patients with mild chronic diarrhea had no excess fecal loss of bile acid. The loss of 14C-24-cholic acid... | 830,889 | [
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0.08978405,
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0.2560866,
0.04181634,
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0.018514... |
Fatty acid patterns of human milk. | An analysis of the fatty acid content of 110 early morning samples of breast milk from 26 mothers shows a shift in the fatty acid pattern toward higher values for C 18:2 fatty acids than those reported previously. This shift has paralleled an increase in the use of vegetable oils and an increase in the P/S ratio of the... | 830,891 | [
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Prenatal diagnosis of mucolipidosis IV by electron microscopy. | Mucolipidosis IV, a recently recognized metabolic storage disease, is characterized clinically by corneal opacity in infancy, full facial features, and psychomotor retardation. Electron microscopy of cells from a 2-year-old affected girl revealed multiple cytoplasmic storage bodies. Cultured amniotic fluid cells, in tw... | 830,895 | [
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Lung mechanics in congenital heart disease with increased and decreased pulmonary blood flow. | Respiratory rate, tidal volume, dynamic lung compliance, functional residual capacity, and pulmonary resistance were measured withim 24 hours of cardiac catheterization in 25 infants, 12 of whom had increased pulmonary blood flow and 13 of whom had decreased PBF. There were no differences in the two groups of patients ... | 830,909 | [
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Antral diaphragm--a cause of gastric outlet obstruction in infants and children. | Gastric outlet obstruction in infants and children may be due to a partial, prepyloric antral diaphragm. Twelve new patients are added to the 32 described previously. Onset of symptoms varied from shortly after birth to five years. Nonbilious vomiting was the most common presenting symptom. Radiographic evaluation requ... | 830,910 | [
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The research component in the development of emergency medicine as a specialty. | The development of emergency medicine as a separate medical specialty involves several major processes, including professional identification, delineation of the dimensions of the specialty, development of a body of knowledge, and creative investigative activities. Residents in emergency medicine offer a potential sour... | 830,946 | [
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Renal cell carcinoma in repeat diagnostic study for persistent hematuria. | A review of 7 cases of misleading, early diagnosis of hematuria is presented. Each patient was found to have renal cell carcinoma on a repeat study for persistent hematuria. Surgical and postoperative followup results are included. | 830,962 | [
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Random mucosal biopsies in the evaluation of patients with carcinoma of the bladder. | The management of patients with recurrent transitional cell carcinoma of the bladder has posed a constant dilemma to the practicing urologist. Previously, urine cytologies have been used and have been of value only in those instances in which they have been classified as diagnostic. Cytologies that reveal atypia or a h... | 830,968 | [
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... |
Antidiuretic hormone levels during cardiopulmonary bypass. | The effect of CPB on plasma ADH levels, urine flow, and urine osmolality was studied in nine patients. All patients received morphine, 1 mg. per kilogram, and 50 per cent nitrous oxide-50 per cent oxygen for anesthesia. CPB utilized a Travenol disposable bubble oxygenator and the prime consisted of 3 L. of Ringer's lac... | 831,006 | [
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Aanerobic isolates in hemovac lines. | Seventeen of 68 patients (25 percent) who required the use of hemovac drainage system after major head and neck procedures had positive anaerobic islates. Co-isolation of aerobic (94 percent) and other anaerobic (29 percent) microorganisms are common. There was an increased rate of psoitive anaerobic islates with proce... | 831,050 | [
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... |
Respiratory-tract colonization and a distinctive pneumonia syndrome in infants infected with Chlamydia trachomatis. | To learn if Chlamydia trachomatis causes in young infants a distinctive penumonia characterized by chronic, afebrile course, diffuse lung involvement and elevated serum immunoglobulins G and M, 47 black infants four to 24 weeks of age were examined for nasopharyngeal shedding of C. trachomatis and serum immunofluoresce... | 831,128 | [
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0.2337179,
0.1220942,
... |
Mixed mesodermal sarcoma of the ovary. | Three cases of mixed mesodermal sarcoma (MMS) are reported and a review of 90 cases from the English literature is presented. All cases were analyzed with regard to clinical features, prognosis, and therapeutic efficacy. The histogenesis of these rare tumors is discussed and a new classification of ovarian sarcomas is ... | 831,181 | [
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... |
Ovarian pregnancy. | Two cases of primary ovarian pregnancy are described. The etiologic, clinical, and pathologic findings and management are discussed briefly with a review of pertinent literature. Routine removal of all bleeding corpora lutea and careful examination of the tissue and blood clots is recommended as this should reveal more... | 831,186 | [
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... |
Cord blood hyperlipoproteinemia and perinatal stress. | In 275 neonates mean cord blood cholesterol level was 70 +/- 17 (SD) mg/dl, with a range from 30 to 153 mg/dl. Mean cord blood triglyceride level was 33 +/- 26 (SD) mg/dl, with a range of 5-192 mg/dl. In an attempt to correlate perinatal problems and hypercholesterolemia in neonates we compared 15 hypercholesterolemic ... | 831,215 | [
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0.1041334,
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Ventricular epicardial activation sequence in the lamb. | The ventricular epicardial activation sequence (VEAS) in 15 anesthetized lambs (near term fetus to 3.5 months of age) was determined using 40 simultaneously recorded bipolar electrograms for each animal. Isochrone maps were drawn by hand using relative activation times determined from the maximum first derivative of mu... | 831,220 | [
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Research experience in an undergraduate physical therapy program. | For the past five years, two required courses in research methodology have been presented to physical therapy students during their senior year. The overall objective was to prepare students to use the scientific method in their approach to physical therapy practice. The content of the first course included didactic in... | 831,225 | [
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[Liver tumors and oral contraceptives. Report of a case and review of the liverature]. | On laparotomy in a 33-year-old woman presenting with signs of chronic cholecystitis and cholelithiasis, a tumor (diameter 4.5 cm) of the right lobe of the liver was found and resected. It proved to be a hamartoma (focal nodular hyperplasia). At the age of 20 years the patient had been treated by radiation and chemother... | 831,247 | [
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Subacute sclerosing panencephalitis: experimental infection in primates. | Measles virus isolated from the brain of a 12-year-old boy with subacute sclerosing panencephalitis caused a chronic, progressive encephalitis in experimentally infected rhesus monkeys. The infection was eventually fatal in spite of pre-existing measles immunity and a vigorous secondary antibody response in serum and c... | 831,255 | [
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Octopine as an end product of anaerobic glycolysis in the chambered nautilus. | The terminal step in the anaerobic glycolysis of muscle in the chambered nautilus, Nautilus pompilius, is not pyruvate reduction to lactate as in vertebrate muscle. Instead of lactate dehydrogenase, these organisms utilize octopine dehydrogenase (E.C. 1.5.1.11), catalyzing the reductive condensation of pyruvate and arg... | 831,256 | [
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... |
Natural selection for juvenile lizards mimicking noxious beetles. | Adult Eremias lugubris in southern Africa are concealingly colored and move with a typical lizard gait, but the jet-black and white juveniles are conspicuous and forage actively with arched backs. In color, gait, and size, juveniles mimic "oogpister" beetles (Carabidae: Anthia) that spray an acidic, pungent fluid when ... | 831,272 | [
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Chloride transport across isolated opercular epithelium of killifish: a membrane rich in chloride cells. | The opercular epithelium of Fundulus heteroclitus contains typical gill chloride-secreting cells at the high density of 4 X 10(5) cells per square centimeter. When isolated, mounted as a membrane, and short-circuited, it actively transports chloride ions from the blood side to the seawater side of the preparation. This... | 831,273 | [
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Stab wounds of the brain. | Unlike the penetrating injuries to the brain caused by missiles, injuries by stabbing are largely restricted to the wound tract. Early recognition, debridement and judicious antibiotic therapy can limit or prevent complications in the management of stab wounds. Among the common sequelae of stab wounds of the brain are ... | 831,365 | [
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Hereditary cholestasis combined with peripheral pulmonary stenosis and other anomalies. | A syndrome consisting of chronic intrahepatic cholestasis with retention of bile acids but with normalization of bile pigment excretion ahd blood lipids, peripheral pulmonary stenosis, vertebral anomalies and a characteristic facies is described in six patients, including a father and his daughter. An autosomal dominan... | 831,382 | [
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Low molecular weight organic acids in the urine of the newborn. | The urinary excretion of seven selected low molecular weight organic acids in normal neonates was measured by gas chromatography. First and third to fourth day of life excretion of the following compounds was significantly unchanged: 3-OH-butyric acid (less than 13 mumol/mmol creatinine), succinic acid (approx. 43 mumo... | 831,385 | [
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Temproary intestinal lactase deficiency in light-treated jaundiced infants. | The intestinal lactase activity in six newborn jaundiced light-treated infants with diarrhea and in eight normal controls were compared by lactose tolerance test (LTT). The ability to hydrolyze lactose was minimal in the jaundiced infants during light-treatment compared to the controls which could absorb lactose very w... | 831,386 | [
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Treating acute hypertensive crisis with sodium nitroprusside. | In patients with dangerously elevated diastolic blood pressures, the titrated intravenous administration of sodium nitroprusside usually reduces blood pressure to near-normal levels in less than an hour. This rapid reduction of pressure is well tolerated by hypertensive patients and probably diminishes the morbidity fr... | 831,390 | [
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Effects of contrast medium on left ventricular pressure and volume with emphasis on coronary artery disease. | Forty-one patients had left ventricular angiography repeated 3 minutes after an initial study in order to evaluate the effect of angiographic contrast medium on left ventricular end-diastolic pressure (EDP) and volume (EDV). Seven patients had no evidence of heart disease (normal group) and 34 patients had coronary art... | 831,416 | [
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Intestinal bypass for obesity a summary and perspective. | Intestinal bypass for obesity can be justified only if the risks of excess weight are higher than those of the surgery. Indications for this surgery need to be carefully defined and the patient and family should clearly understand the potential risks and benefits. Weight loss results from a decrease in food intake, alt... | 831,434 | [
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... |
Morbid obesity: problems associated with operative management. | A review of the problems associated with extensive jejunoileal bypass for morbid obesity in a series of 175 carefully selected patients is presented. Five postoperative deaths occurred (3%). Nonfatal complications occurred in 21%, with wound infections (14 patients) being the most common. Good results marked by weight ... | 831,443 | [
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0.02820749,
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0.2188609,
0.03327203,
-0.1493148,
-0.132412... |
Normotest--thrombotest discrepancy in congenital coagulation disorders of the prothrombin complex and in coumarin-treated patients: a nonspecific phenomenon. | A Normotest (NT)-Thrombotest (TT) discrepancy is claimed to reflect the presence of coumarin-induced inhibitors or intravascular coagulation, or both. The results of this study indicate, however, that a significant NT-TT discrepancy is also present in all plasmas from patients who have congenital coagulation disorders ... | 831,455 | [
-0.2253898,
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Field trial of live attenuated influenza A/B ("Alice"/R-75) vaccine. | The reactogenicity, immunogenicity and protection effecacy of a serum inhibitor-resistant live attenuated influenza A/B ("Alice"/R-75) vaccine was determined in a group of health young volunteers. The influenza A component was derived from A/England/42/72 (H3N2) strain, and the B component from B/Hong Kong/5/72 strain.... | 831,465 | [
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Intravascular volume determinations and fetal outcome in hypertensive diseases of pregnancy. | With the Evans blue technique, 178 plasma volume, blood volume, and red cell volume determinations were studied in 51 hypertensive and 35 normotensive gravidas. Hypertensive pregnancies were classified according to the American Committee on Maternal Welfare schema. A large range and overlap in plasma and blood volume d... | 831,484 | [
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Ovarian extraembryonal teratoma. I. Endodermal sinus tumor. | Forty-one cases of pure endodermal sinus ovarian tumors are reported. The extraembryonal nature of this tumor is supported with comparative studies utilizing early human implantations. The clinical picture is one of a virulent malignancy occurring in young women, and although the tumor is commonly unilateral and encaps... | 831,487 | [
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Observation and treatment of neonatal narcotic withdrawal. | A total of 110 infants born to mothers who were either in a methadone maintenance program, using heroin, or recently detoxified, were studied during the neonatal period. Of these infants, 93.6 per cent developed withdrawal symptoms. No significant differences were determined in therapeutic response among those infants ... | 831,502 | [
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Communication patterns and problems of pregnancy. | Communication patterns of women who had never been pregnant were compared with those of women who had two or more unplanned pregnancies. Results of a questionnaire assessing communication skills, social orientation and involvement, self-disclosure, physical accessibility, and verbal defensiveness, completed by 56 women... | 831,522 | [
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Trigenerational enmeshment: unresolved ties of single-parents to family of origin. | Some divorced single-parent mothers return home to live with their families of origin. The absence of clear delineation of the roles of grandmother, mother, and child can produce a dysfunctional family unit, identified here as trigenerational enmeshment. Clinical features of this subgroup are discussed, and examples of... | 831,527 | [
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0.05449611,
0.008313... |
Prevalence of vitiligo. Epidemiological survey on the Isle of Bornholm, Denmark. | The prevalence of vitiligo was 0.38% in 47,033 people in a representative region in Denmark. Both sexes were equally affected. No significant difference was found in the distribution of 179 patients with vitiligo among five municipalities or between urban and rural districts. The age-specific prevalence increased from ... | 831,622 | [
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Comparison of lymphedema following incontinuity and discontinuity groin dissection. | Wide excision of primary malignant melanoma en bloc with regional lymphadenectomy decreases the incidence of regional recurrence as compared with a discontinuous dissection. The more extensive soft tissue defect of the incontinuity procedure is of concern since major lymphatics are often ablated from the ankle region u... | 831,632 | [
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Diverticulitis with perforation into the peritoneal cavity. | Sigmoid diverticulitis with free perforation or perforation through the mesentery results in generalized peritonitis. Emergency surgical treatment is mandatory, but the most efficacious procedure has not been clearly established. Ten consecutive patients were treated by removal of the perforated sigmoid colon, temporar... | 831,638 | [
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... |
Intraoperative application of intraaortic balloon counterpulsation determined by clinical monitoring of the endocardial viability ratio. | Persistent unrecognized subendocardial ischemia with development of subendocardial necrosis is a major cause of patient death following cardiopulmonary bypass. The lesion is caused by a discrepancy between the oxygen needs of subendocardial muscle and the available blood supply. If sole reliance is placed upon monitori... | 831,644 | [
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Circular myotomy of the esophagus: clinical application in esophageal atresia. | Three infants born with esophageal atresia that was repaired by end-to-end anastomosis combined with a circular myotomy on the upper segment are reported. The distance between the free surgical margins of the esophagus ranged between 1.5 and 4.5 cm. The esophageal myotomy was used to reduce the tension on the anastomos... | 831,646 | [
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Esophageal myectomy for recurrent multiple leiomyomas of the esophagus: manometric and cineradiographic documentation. | This is a report of recurrent multiple leiomyomas of the esophagus treated initially by enucleation and subsequently by myectomy of the involved portion of the esophagus to prevent further recurrence. Experimental studies support the clinical observation that the esophagus will function as a conduit for food in the abs... | 831,647 | [
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Hyperuricemic acute renal failure in disseminated carcinoma. | A patient with widespread adenocarcinoma of gastrointestinal tract origin was seen in renal failure. He had extreme hyperuricemia, and at autopsy, uric acid crystals were demonstrated in many collecting structures of the kidney. To our knowledge, this is the first clinicopathologic description of hyperuricemic renal fa... | 831,657 | [
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Idiopathic rupture of the iliac vein. | Idiopathic rupture of large veins is very rare. There has been one report in the Portugese literature of such an instance involving the iliac vein. Our patient was an elderly woman in whom evidence of intra-abdominal hemorrhage developed. There was no clinical evidence of trauma. At laparotomy a large retroperitoneal h... | 831,681 | [
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Fine structure of the cerebellar cortex in Menkes Kinky-hair disease. X-chromosome-linked copper malabsorption. | The cerebellar cortices in two patients with X-chromosome-linked copper malabsorption (Menkes kinky-hair disease) were examined with both the light and electron microscope. Somatic sprouts and grotesque dendritic arborization were among the obvious light microscopical changes. At the fine structural level, the Purkinje... | 831,687 | [
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Medical student performance skills in otolaryngology. | A clinical rating scale was developed to assess clinical skills of third-year medical students completing a two-week required clerkship in otolaryngology. Thirty-seven students in six consecutive small groups were rated with the instrument by themselves, their student peers, and the departmental staff, and the ratings ... | 831,692 | [
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Subdermal fascial augmentation. | A technique is described whereby limited soft tissue defects may be cosmetically improved using autogenous fascial strips. These strips of fascia lata are threaded onto a cadaveric needle that is tunneled subdermally, in a "basket weaving," criss-crossed fashion, augmenting the soft tissue defect and separating the sca... | 831,697 | [
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... |
Analysis of the human voice as a method of controlling emotional state: achievements and goals. | Background factors and those of formant structure, spectral and spectro-temporal characteristics of rapid and slow speech components, temporal peculiarities, and intensity of speech turned out to be informative indices of the human emotional state. Application of mathematical methods, in particular methods of recogniti... | 831,707 | [
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Bubble formation within decompressed hen's eggs. | Decompression sickness follows a reduction in ambient pressure and is a result of bubble formation in blood or tissues. The origin of such bubbles is the subject of considerable controversy, and a number of mechanisms have been proposed to account for them. In testing these mechanisms, freshly-laid hen's eggs provide a... | 831,713 | [
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Comparison of susceptibility to motion sickness during rotation at 30 rpm in the earth-horizontal, 10 degrees head-up, and 10 degrees head-down positions. | Normal persons rotated about an Earth-horizontal axis vary in their susceptibility to motion sickness. The purpose of this experiment was to measure, intraindividual differences in susceptibility in 12 subjects when rotated 10 degrees head up and 10 degrees head down as well as in the horizontal position. Subjects assu... | 831,718 | [
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Measurement of postoperative pericardial pressure in man. | Pericardial pressure was measured in 18 patients undergoing cardiopulmonary bypass for up to 10 days using a solid state transducer. Mean and phasic pericardial pressure wave forms were similar to those reported in animals. A wide range of mean pressure from 0 to 30 mmHg was recorded, and values of up to 20 mmHg were o... | 831,731 | [
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Observations on squamous cell carcinomas of sheep in Queensland, Australia. | Observations were made over a 4-year period on squamous cell carcinomas on the ear and other areas poorly covered by hair or wool, sheep pastured in the hot, dry environment of north-western Queensland. Overall incidence in the flock was higher than in flocks kept at greater latitudes. Increased incidence with advancin... | 831,756 | [
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Lignocaine aerosol and persistent cough. | Four patients with intractable cough improved for periods of between one and six weeks after treatment with 400 mg of lignocaine by aerosol spray. Suprisingly the lignocaine increased airways resistance in some of them. It is suggested that the excessive cough is due to excessive sensitivity of tracheal cough or irrita... | 831,764 | [
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Unilateral lung disease detected by radioisotopic scanning in children thought to have asthma. | The clinical courses of three children are described. They were initially thought to have troublesome asthma alone or in association with other diseases. The children had radioactive gas lung scans using 13N for studies of ventilation and perfusion which in each case revealed one entirely healthy lung and one disordere... | 831,770 | [
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Effect of a single cis double bond on the structures of a phospholipid bilayer. | The ordering of the hydrocarbon chains and the rates of lipid motion are two independent parameters characterizing the structure and the dynamics, respectively, of a bilayer membrane. In this work, deuterium magnetic resonance has been used to elucidate the influence of a single cis double bond on the hydrocarbon chain... | 831,777 | [
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Light scattering and excitation in lobster giant axon. Effects of ion substitution. | Changes in the light scattering signal from single giant axons of lobster were observed during the propagation of the action potential in order to correlate membrane excitability with possible structural changes reflected in the optical properties of the axolemma. Substitution of guanidine and aminoguanidine for sodium... | 831,790 | [
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... |
Membrane mediated link between ion transport and metabolism in human red cells. | When 10(-6) M oubain is added to human red cell that have been incubated without glucose for two hours, there is a significant shift in the 31P nuclear magnetic resonances of both phosphate groups of cellular 2,3-diphosphoglycerate, which is not found in control cells incubated with glucose. This means that an effect i... | 831,795 | [
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0.315209,
-0.1045574,
0.04643063... |
Effect of angiotensin II on artificial lipid membranes. | (5-Isoleucine)-angiotensin II applied to black lipid membranes produced current fluctuations varying between deltaG=5-10(-11) omega-1 and 3.5-10(-10) omega(-1). These fluctuations depend on the voltage and the hydrostatic pressure. The membrane resistance is lowered by deltaR=6.1-10(7) omega-cm2. With (5-isoleucine, 8-... | 831,803 | [
-0.388681,
-0.0591913,
-0.7291142,
-0.2877226,
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0.04146265,
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0.1323747,
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0.2321861,
0.05664293,
0.09289874,
-0.03180704,
... |
Platinum - dimethylsulphoxide as a specific nucleic acid reagent for base sequence determination by electron microscopy. | The reaction of platinum (II) - dimethylsulphoxide complex with the bases of the nucleic acids were investigated with a new towards their use as heavy atom markers for base sequence determination by electron microscopy. Both at pH 6.0 and pH 7.5 one platinum atom was bound simultaneously to the pyrimidines and two to a... | 831,822 | [
-0.1458805,
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0.2928849,
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0.3183795,
0.4125649,
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0... |
Analysis by two-dimensional polyacrylamide gel electrophoresis of liver ribosomal subunnit proteins obtained from free and membrane-bound polysomes of unfasted animals. | Ribosomal proteins were analyzed by means of two-dimensional gel electrophoresis. To insure that the analysis included only that fraction of the ribosome actively participating in protein synthesis, only polysomal-bound ribosomes were used. This differs from previously reported analyses of liver ribosomal proteins. The... | 831,825 | [
0.07966271,
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0.09564308,
0.5026703,
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0.05437913,
... |
Localization, purification and substrate specificity of monoamine oxidase. | Bovine kidney monoamine oxidase (amine:oxygen oxidoreductase (deaminating) (flavin-containing), EC 1.4.3.4) has been purified to one band on disc electrophoresis, and is shown to be localized in the intra- and extramitochondrial membrane. Kinetic models have been used to determine the effect of different substances on ... | 831,837 | [
-0.2546346,
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0.2117356,
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0.3161235,
0.2665092,
-0.215794... |
Exciton annihilation in the two photosystems in chloroplasts at 100 degrees K. | The fluorescence yield (F) of spinach chloroplasts at 100 degrees K measured at 735 nm (photosystem I fluorescence-F 735) and at 685 nm (photosystem II fluorescence-F 685) has been determined with different modes of laser excitation. The modes of excitation included a single picosecond pulse, sequences of picosecond pu... | 831,854 | [
-0.1515497,
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0.05981923,
0.6050855,
0.4522115,
-0.1601345,... |
Steady-state electrodiffusion. Scaling, exact solution for ions of one charge, and the phase plane. | This is the first of two papers dealing with electrodiffusion theory (the Nernst-Planck equation coupled with Gauss's law) and its application to the current-voltage behavior of squid axon. New developments in the exact analysis of the steady-state electrodiffusion problem presented here include (a) a scale transformat... | 831,855 | [
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0.124106,
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0.2101396,
0.05153571,
0.1445678,... |
Exclusion in hyaluronate gels. | Osmotic pressures of solutions of hyaluronate (HA) (mol wt 117,000) and mixtures of HA and bovine serum albumin (BSA) in phosphate-buffered saline, pH 7.2 were measured with a membrane osmometer. The data were fit with a virial expansion in integral powers of total nondiffusible solute concentration. Values of number a... | 831,856 | [
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0.1885376,
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0.1942465,
-0.258615,
-0.04539268... |
Electrical properties of frog skeletal muscle fibers interpreted with a mesh model of the tubular system. | This paper presents the construction, derivation, and test of a mesh model for the electrical properties of the transverse tubular system (T-system) in skeletal muscle. We model the irregular system of tubules as a random network of miniature transmission lines, using differential equations to describe the potential be... | 831,857 | [
0.2392994,
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0.3335295,
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0.3387682,
0.08934246,
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... |
Development of criteria and procedures for appointment, promotion, and tenure of library faculty in an academic health sciences library. | A subcommittee of the Appointment, Promotion and Tenure Committee was appointed to develop a document establishing procedures and criteria for the appointment, promotion, and tenure of library faculty at the Library of the Health Sciences, University of Illinois. The subcommittee analyzed the library's objectives withi... | 831,885 | [
-0.329398,
0.3006507,
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0.4012205,
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0.2292002,
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0.3341,
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0.233044,
0.2035158,
-0.06520227,
... |
Dermatoglyphics in schizophrenia: the relevance of positive family history. | In the present study dermatoglyphic features were studied in schizophrenics with and without positive family history of schizophrenia. It was found that the difference between normals and schizophrenics was further exaggerated in those schizophrenics with a positive family history for schizophrenia. The implications of... | 831,909 | [
0.1577242,
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0.1620182,
0.1522339,
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-0.05336471,
0.1808812,
-0.1431381... |
Effect of rotation on radiographic dimensions of the humerus and femur. | Ten humeri and ten femora were radiographed in nine positions of longitudinal rotation. In each position total, medullary and cortical widths of the diaphyses (TW, MW, CW) were measured to assess the effect of rotation on these dimensions. The results were expressed as differences from the values in the neutral positio... | 831,915 | [
-0.06758719,
0.3560475,
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-0.2136812,
0.01135493,
0.2255414,
-0.08697578,
-0.057737... |
Effects of radiation on the visual appearance and mechanical properties of mouse skin. | A study of the long term effects of radiation on the visual appearance and mechanical properties of mouse skin is presented. The effects associated with the hair follicle (greying and alopecia) increase monotonically with exposure. Other effects (load, extension and stress at rupture and scarring of the skin) all show ... | 831,931 | [
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-0.2444899,
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0.1261226,
-0.223378,
0.2357758,
0.01671115,
-0.04330546,
-0.201742... |
The pathophysiological changes of experimental fat embolism: early pre-hypoxaemic changes. | Glyceryl trioleate has been injected into greyhounds as a model of the fat embolism syndrome. Pulmonary vascular pressures, systemic arterial pressure and cardiac output were determined at regular intervals over an 8-hour period. It has been shown that glyceryl tioleate causes an increased pulmonary vascular resistance... | 831,959 | [
0.04611091,
0.07297707,
-0.5024503,
-0.01736842,
0.157163,
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0.0590077,
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0.02225155,
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0.32987,
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0.002225495,
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0.4067771,
0.103303,
0.2877275,
-0.1826923,
0... |
Lumbar epidural analgesia in labour: relation to fetal malposition and instrumental delivery. | The incidence of instrumental delivery and malposition immediately before delivery was compared in patients who were given lumbar epidural analgesia and those who were not. Instrumental delivery was five times more common and a malposition of the fetal head was more than three times as common in the epidural group as i... | 831,964 | [
0.2327683,
0.186892,
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0.1289881,
0.04420051,
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0.4034448,
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0.2370505,
0.4925975,
-0.04156429,
... |
Domiciliary care for the elderly sick--economy or neglect? | This paper reports an investigation of the costs of domiciliary care for 139 elderly sick patients under the care of the home nursing service. The data suggest that there may be little economic advantage in home care for seriously disabled elderly people. The revenue cost of domiciliary care was equal to or greater tha... | 831,975 | [
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0.3313902,
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0.1124233,
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0.2356446,
0.288... |
Do fat babies stay fat? | A total of 203 children included in a study of feeding practices and weight in infancy were reviewed four to five years later. Although in infancy 28 (14%) of the children were obese and a further 52 (26%) overweight, in childhood most were of normal weight and fatness, with only 5 (2-5%) obese and 22 (11%) overweight,... | 832,000 | [
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-0.03973226,
0.3067409,
-0.2351825,
0.04585204,
0.2207778,
0.2799736,
0.025714... |
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