title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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A comparison between electrical uterine monitor, tocodynamometer and intra uterine pressure catheter for uterine activity in labor. | We aimed to evaluate the performance of a non-invasive EMG electrical uterine monitor (EUM) versus tocodynamometry (TOCO) by comparing both to internal uterine pressure catheter (IUPC). Prospective observational trial. Uterine activity was recorded continuously and simultaneously, in women during active term labor, wit... | 25,123,517 | [
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Brain stem/brain stem occipital bone ratio and the four-line view in nuchal translucency images of fetuses with open spina bifida. | Abstract Objective: Brain stem depth/brain stem occipital bone distance (BS/BSOB ratio) and the four-line view, in images obtained for nuchal translucency (NT) screening in fetuses with open spina bifida (OSB). Methods: Single center, retrospective study based on the assessment of NT screening images of fetuses with OS... | 25,123,518 | [
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Use of magnetic resonance imaging in detecting subclinical synovitis in rheumatoid arthritis and correlation of imaging findings with interleukin-18 levels. | We studied the usefulness of magnetic resonance imaging (MRI) in detecting subclinical inflammation in patients with asymptomatic RA and tested the hypothesis of interleukin (IL)-18 as a marker of disease activity. Thirteen RA patients with Disease Activity Score of 28 joints (DAS28) < 2.6 were evaluated. The patien... | 25,123,522 | [
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Volume assured versus pressure preset non-invasive ventilation for compensated ventilatory failure in COPD. | The addition of domiciliary non-invasive ventilation (NIV) to standard therapy in chronic obstructive pulmonary disease (COPD) patients with compensated ventilatory failure (CVF) is reported to have beneficial effects. Compliance with NIV is an important factor. Volume assured NIV (va-NIV) may improve compliance and ve... | 25,123,526 | [
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Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development. | In this study, we have investigated genome-wide occurrence of Histone Acetyltransferases (HATs) in genomes of Mus musculus and Danio rerio on the basis of presence of HAT domain. Our study identified a group of proteins that lacks characteristic features of known HAT families, relatively smaller in size and has no othe... | 25,123,547 | [
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Bedside ultrasound curriculum for medical students: report of a blended learning curriculum implementation and validation. | Medical students on clinical rotations rarely receive formal bedside ultrasound (BUS) training. We designed, implemented, and evaluated a standardized BUS curriculum for medical students on their Emergency Medicine (EM) rotation. Teaching was aimed toward influencing four cognitive and psychomotor learning domains: BUS... | 25,123,564 | [
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Isolated III cranial nerve palsies may point to primary histiocytic sarcoma. | Primary histiocytic sarcoma (HS) of the central nervous system (CNS) is a rare haematopoietic neoplasm. The inconsistent terminology and diagnostic criteria currently used for CNS HS have complicated the appreciation of the clinical aspects of the disease. The main differential diagnoses are non-Hodgkin's lymphoma, rea... | 25,123,571 | [
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Techniques to measure sorption and migration between small molecules and packaging. A critical review. | The mass transfer parameters diffusion and sorption in food and packaging or between them are the key parameters for assessing a food product's shelf-life in reference to consumer safety. This has become of paramount importance owing to the legislations set by the regulated markets. The technical capabilities that can ... | 25,123,587 | [
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Boosting the power conversion efficiency of perovskite solar cells using self-organized polymeric hole extraction layers with high work function. | A self-organized hole extraction layer (SOHEL) with high work function (WF) is designed for energy level alignment with the ionization potential level of CH3 NH3 PbI3 . The SOHEL increases the built-in potential, photocurrent, and power conversion efficiency (PCE) of CH3 NH3 PbI3 perovskite solar cells. Thus, interface... | 25,123,592 | [
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A team fares well with a fair coach: Predictors of social loafing in interactive female sport teams. | The present research aimed to develop and test a theoretical model that links players' perceived justice of the coach to a more optimal motivational climate, which in turn increases players' team identification and cohesion, and results in lower levels of social loafing in female sport teams. Belgian elite female baske... | 25,123,599 | [
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Rural palliative care transitions from home to hospital: carers' experiences. | To document carer perceptions of patients' transitions from community to hospital-based palliative care in a rural setting. A qualitative study using an interview method at two time points. Rural palliative care providers: Kyneton District Health Service and the Macedon Ranges Palliative Care Service, Victoria. Six adu... | 25,123,619 | [
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A comprehensive survey of non-canonical splice sites in the human transcriptome. | We uncovered the diversity of non-canonical splice sites at the human transcriptome using deep transcriptome profiling. We mapped a total of 3.7 billion human RNA-seq reads and developed a set of stringent filters to avoid false non-canonical splice site detections. We identified 184 splice sites with non-canonical din... | 25,123,659 | [
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Epidemiological characteristics and immune status of children with Respiratory Syncytial Virus. | Respiratory Syncytial Virus (RSV) infections are the dominant cause of pneumonia in children. In order to determine the epidemiological characteristics and immune status of children with Respiratory Syncytial Virus, a prospective study was performed among patients with RSV infection. Comparisons between RSV pneumonia g... | 25,123,681 | [
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A 4-fold-symmetry hexagonal ruthenium for magnetic heterostructures exhibiting enhanced perpendicular magnetic anisotropy and tunnel magnetoresistance. | A 4-fold-symmetry hexagonal Ru emerging in epitaxial MgO/Ru/Co2 FeAl/MgO heterostructures is reported, in which an approximately Ru(022¯3) growth attributes to the lattice matching between MgO, Ru, and Co2 FeAl. Perpendicular magnetic anisotropy of the Co2 FeAl/MgO interface is substantially enhanced. The magnetic tunn... | 25,123,705 | [
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Technical challenges for big data in biomedicine and health: data sources, infrastructure, and analytics. | To review technical and methodological challenges for big data research in biomedicine and health. We discuss sources of big datasets, survey infrastructures for big data storage and big data processing, and describe the main challenges that arise when analyzing big data. The life and biomedical sciences are massively ... | 25,123,720 | [
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Big data - smart health strategies. Findings from the yearbook 2014 special theme. | To select best papers published in 2013 in the field of big data and smart health strategies, and summarize outstanding research efforts. A systematic search was performed using two major bibliographic databases for relevant journal papers. The references obtained were reviewed in a two-stage process, starting with a b... | 25,123,721 | [
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Reasons (not) to Spend a Few Billions More on EHRs: How Human Factors Research Can Help. | To select best medical informatics research works published in 2013 on electronic health record (EHR) adoption, design, and impact, from the perspective of human factors and organizational issues (HFOI). We selected 2,764 papers by querying PubMed (Mesh and TIAB) as well as using a manual search. Papers were evaluated ... | 25,123,727 | [
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Big data and smart health strategies: findings from the health information systems perspective. | To summarize excellent current research in the field of Health Information Systems. Creation of a synopsis of the articles selected for the 2014 edition of the IMIA Yearbook. Four papers from international peer reviewed journals were selected and are summarized. Selected articles illustrate current research regarding t... | 25,123,731 | [
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A Review and Framework for Categorizing Current Research and Development in Health Related Geographical Information Systems (GIS) Studies. | The application of GIS in health science has increased over the last decade and new innovative application areas have emerged. This study reviews the literature and builds a framework to provide a conceptual overview of the domain, and to promote strategic planning for further research of GIS in health. The framework i... | 25,123,730 | [
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IBM's Health Analytics and Clinical Decision Support. | This survey explores the role of big data and health analytics developed by IBM in supporting the transformation of healthcare by augmenting evidence-based decision-making. Some problems in healthcare and strategies for change are described. It is argued that change requires better decisions, which, in turn, require be... | 25,123,736 | [
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Optimizing multiple-choice tests as tools for learning. | Answering multiple-choice questions with competitive alternatives can enhance performance on a later test, not only on questions about the information previously tested, but also on questions about related information not previously tested-in particular, on questions about information pertaining to the previously incor... | 25,123,774 | [
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TRAIL expression levels in human hepatocellular carcinoma have implications for tumor growth, recurrence and survival. | The proapoptotic molecule TNF-related apoptosis-inducing ligand (TRAIL) has earned attention because of its ability to induce apoptosis in liver cancer cells without damaging normal liver cells. It may play an important role in preventing the development and outgrowth of hepatocellular carcinoma (HCC). TRAIL expression... | 25,123,818 | [
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Y-chromosome analysis in a Northwest Iberian population: unraveling the impact of Northern African lineages. | To provide new clues about the genetic origin, composition and structure of the population of the Spanish province of Zamora, with an emphasis on the genetic impact of the period of Islamic rule in the Iberian Peninsula. Polymorphisms in the paternally inherited Y-chromosome, Single Nucleotide Polymorphisms and Short T... | 25,123,837 | [
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Penta-O-galloyl-β-D-glucose suppresses EGF-induced eIF3i expression through inhibition of the PI3K/AKT/mTOR pathway in prostate cancer cells. | Approximately 70% of prostate cancer patients will develop bone metastasis in axial and other regions of the skeleton. Epidermal growth factor (EGF) generated from bone tissue contributes to prostate cancer metastasis. In a previous study, penta-O-galloyl-β-D-glucose (PGG) suppressed androgen-independent prostate cance... | 25,123,845 | [
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The pros and cons of funnel plots as an aid to risk communication and patient decision making. | Funnel plots, which simultaneously display a sample statistic and the corresponding sample size for multiple cases, have a range of applications. In medicine, they are used to display treatment outcome rates and caseload volume by institution, which can inform strategic decisions about health care delivery. We investig... | 25,123,852 | [
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[Urbanization of Chagas disease in Peru: experiences in prevention and control]. | In Peru, Chagas disease has an epidemiological significance in three macro-regions, one of them is the southern macro-region formed by the departments of Arequipa, Moquegua and Tacna. In 1965 a successful control was performed by house spraying insecticides, however, the persistence of the vector made it necessary for ... | 25,123,876 | [
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[Sporotrichosis and paracoccidioidomycosis in Peru: experiences in prevention and control]. | The epidemiological picture of sporotrichosis and paracoccidioidomycosis in Peru and Latin America is sporadic, fragmented, and geographically limited, mainly due to lack of mandatory reporting and limited diagnostic coverage. However, research contributions related to understanding the interaction of these fungi, the ... | 25,123,878 | [
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[Acute arterial occlusion associated disseminated hydatidosis]. | Hydatidosis or echinococcosis are terms used to denote the zoonotic infestation caused by adult and larval stages (metacestode) of the cestode from the genus Echinococcus (family tenidae). The term hydatidosis should be applied to the infestation caused by the metacestode while echinococcosis for the larval and adult s... | 25,123,882 | [
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READemption-a tool for the computational analysis of deep-sequencing-based transcriptome data. | RNA-Seq has become a potent and widely used method to qualitatively and quantitatively study transcriptomes. To draw biological conclusions based on RNA-Seq data, several steps, some of which are computationally intensive, have to be taken. Our READemption pipeline takes care of these individual tasks and integrates th... | 25,123,900 | [
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Genetic architecture of ALS in Sardinia. | Conserved populations, such as Sardinians, displaying elevated rates of familial or sporadic amyotrophic lateral sclerosis (ALS) provide unique information on the genetics of the disease. Our aim was to describe the genetic profile of a consecutive series of ALS patients of Sardinian ancestry. All ALS patients of Sardi... | 25,123,918 | [
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Cell responses to metallic nanostructure arrays with complex geometries. | Metallic nanopillar/nanowires are emerging as promising platforms for biological applications, as they allow for the direct characterization and regulation of cell function. Herein we study the response of cells to a versatile nanopillar platform. Nanopillar arrays of various shape, size, and spacing and different nano... | 25,123,921 | [
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Mitotic DNA damages induced by carbon-ion radiation incur additional chromosomal breaks in polyploidy. | Compared with low linear energy transfer (LET) radiation, carbon-ion radiation has been proved to induce high frequency of more complex DNA damages, including DNA double strands (DSBs) and non-DSB clustered DNA lesions. Chemotherapeutic drug doxorubicin has been reported to elicit additional H2AX phosphorylation in pol... | 25,123,929 | [
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Detection of cyanobacterial neurotoxin β-N-methylamino-l-alanine within shellfish in the diet of an ALS patient in Florida. | Cyanobacteria produce the neurotoxic amino acid β-N-methylamino-l-alanine (BMAA), which in contaminated marine waters has been found to accumulate in shellfish. Exposure to BMAA has been associated with an increased risk of neurodegenerative disease. Analysis of blinded samples found BMAA to be present in neuroproteins... | 25,123,936 | [
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Determination of trace amount of formaldehyde base on a bromate-Malachite Green system. | A novel catalytic kinetic spectrophotometric method for determination of trace amount of formaldehyde (FA) has been established, based on catalytic effect of trace amount of FA on the oxidation of Malachite Green (MG) by potassium bromate in presence of sulfuric acid medium, and was reported for the first time. The met... | 25,123,939 | [
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Spectroscopic analyses and studies on respective interaction of cyanuric acid and uric acid with bovine serum albumin and melamine. | In this work, the fluorescence quenching was used to study the interaction of cyanuric acid (CYA) and uric acid (UA) with bovine serum albumin (BSA) at two different temperatures (283 K and 310 K). The bimolecular quenching constant (Kq), apparent quenching constant (Ksv), effective binding constant (KA) and correspond... | 25,123,940 | [
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FT-IR and FT-Raman studies of cross-linking processes with Ca(2+) ions, glutaraldehyde and microwave radiation for polymer composition of poly(acrylic acid)/sodium salt of carboxymethyl starch--part I. | FT-IR and FT-Raman spectroscopic methods allowed to identify the cross-linking process of the aqueous composition of poly(acrylic acid)/sodium salt of carboxymethyl starch (PAA/CMS-Na) applied as a binder for moulding sands. The cross-linking was performed by chemical methods by introducing cross-linking substances wit... | 25,123,942 | [
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Optimizing Rubisco and its regulation for greater resource use efficiency. | Rubisco catalyses the carboxylation of ribulose-1,5-bisphosphate (RuBP), enabling net CO2 assimilation in photosynthesis. The properties and regulation of Rubisco are not optimal for biomass production in current and projected future environments. Rubisco is relatively inefficient, and large amounts of the enzyme are n... | 25,123,951 | [
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Co-inoculation of Glomus intraradices and Trichoderma atroviride acts as a biostimulant to promote growth, yield and nutrient uptake of vegetable crops. | The application of beneficial microorganisms at transplanting can promote rapid transplant establishment (starter effect) for achieving early and high yields. The aim of this study was to evaluate the biostimulant effects of Glomus intraradices BEG72 (G) and Trichoderma atroviride MUCL 45632 (T) alone or in combination... | 25,123,953 | [
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[Argentinean general practitioners' practice and counseling regarding physical activity]. | Investigating general practitioners' (GP) physical activity and to what extent their own physical activity affects counselling their patients in clinical practice. This was a cross-sectional, exploratory study; sample size was 115 (82 women and 33 men). The survey involved using a self-administered questionnaire at the... | 25,124,003 | [
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[A glossary for health care promoting universities (an HPU glossary)]. | The health promotion in the university context emerges as an important initiative to facilitate the development of healthy lifestyle behaviors in this environment where students, faculty and university staff spend and share a significant part of their lives. The movement of Health Promoting Universities (HPU) has over ... | 25,124,004 | [
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Robot-assisted remote echocardiographic examination and teleconsultation: a randomized comparison of time to diagnosis with standard of care referral approach. | The strategy using cardiological consultation in addition to the robot-assisted remote echocardiography at a distance was tested in a prospective, randomized open-label trial to evaluate its feasibility and to define its clinical value in a rural area. The present study involved 1 primary healthcare center in the north... | 25,124,011 | [
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Stochastic population forecasting based on combinations of expert evaluations within the Bayesian paradigm. | This article suggests a procedure to derive stochastic population forecasts adopting an expert-based approach. As in previous work by Billari et al. (2012), experts are required to provide evaluations, in the form of conditional and unconditional scenarios, on summary indicators of the demographic components determinin... | 25,124,024 | [
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Effects of familiar contingencies on infants' vocal behavior in new communicative contexts. | Recently, there has been a growing interest in understanding the mechanisms underlying vocal learning in songbirds and human infants. Research has demonstrated how contingent social feedback from social partners to immature vocalizations can play a role during vocal learning in both brown-headed cowbirds and prelinguis... | 25,124,029 | [
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The effect of spine postures on the hydrodynamic drag in Epinephelus ongus larvae. | Laboratory behavioural observation and computational fluid dynamics (CFD) analysis were conducted to examine whether the movement of the elongated dorsal and pelvic spines changed the hydrodynamic drag in white-streaked grouper Epinephelus ongus larvae. The behavioural observation in the tank revealed that the larvae e... | 25,124,030 | [
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Newborn screening for pompe disease? a qualitative study exploring professional views. | Developments in enzyme replacement therapy have kindled discussions on adding Pompe disease, characterized by progressive muscle weakness and wasting, to neonatal screening. Pompe disease does not fit traditional screening criteria as it is a broad-spectrum phenotype disorder that may occur in lethal form in early infa... | 25,124,044 | [
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Memories as bifurcations: realization by collective dynamics of spiking neurons under stochastic inputs. | How the neural system proceeds from sensory stimuli to generate appropriate behaviors is a basic question that has not yet been fully answered. In contrast to the conventional viewpoint, in which the external stimulus dominantly drives the response behavior, recent studies have revealed that not only external stimuli, ... | 25,124,069 | [
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Bronchoscopic interventions for chronic obstructive pulmonary disease. | Over the past decade, several non-surgical and minimally invasive bronchoscopic lung volume reduction (BLVR) techniques have been developed to treat patients with severe chronic obstructive pulmonary disease (COPD). BLVR can be significantly efficacious, suitable for a broad cohort of patients, and associated with a so... | 25,124,070 | [
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Vascular endothelial growth factor A polymorphism and risk of Kaposi's sarcoma herpesvirus viremia in kidney allograft recipients. | Kaposi's sarcoma herpesvirus (KSHV) causes Kaposi's sarcoma (KS), primary effusion lymphoma, and multicentric Castleman's disease in immunocompromised patients including allograft recipients. Detection of KSHV DNA in blood, as well as host genetic polymorphisms has been found to be associated with an increased risk for... | 25,124,076 | [
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Stigma and the perpetuation of obesity. | Even as obesity rates reach new highs, the social stigmatization of obesity seems to be strengthening and globalizing. This review identifies at least four mechanisms by which a pervasive environment of fat stigma could reinforce high body weights or promote weight gain, ultimately driving population-level obesity. The... | 25,124,079 | [
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Asymmetric gold-catalyzed lactonizations in water at room temperature. | Asymmetric gold-catalyzed hydrocarboxylations are reported that show broad substrate scope. The hydrophobic effect associated with in situ-formed aqueous nanomicelles gives good to excellent ee's of product lactones. In-flask product isolation, along with the recycling of the catalyst and the reaction medium, are combi... | 25,124,085 | [
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Identifying optimal biomarker combinations for treatment selection via a robust kernel method. | Treatment-selection markers predict an individual's response to different therapies, thus allowing for the selection of a therapy with the best predicted outcome. A good marker-based treatment-selection rule can significantly impact public health through the reduction of the disease burden in a cost-effective manner. O... | 25,124,089 | [
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Norwegian nursing and medical students' perception of interprofessional teamwork: a qualitative study. | Little is known about the ways in which nursing and medical students perceive and understand their roles in interprofessional teamwork. A 2010 report by the World Health Organization highlights the importance of students' understanding of teamwork in healthcare, and their ability to be effective team players. This stud... | 25,124,090 | [
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The advantage of professional organizations as advocates for improved funding of maternal and child health services in Uganda. | The attainment of United Nations Millennium Development Goal 5 has proven elusive for many countries. Efforts to reduce maternal mortality require concerted evidence-based efforts from all key players, including professional organizations. The Association of Obstetricians and Gynaecologists of Uganda used the results o... | 25,124,100 | [
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Plasmapheresis may be an option in urgent management of heparin-induced thrombocytopenia in the setting of acute intracerebral hemorrhage. | We report a case of heparin-induced thrombocytopenia (HIT) that was complicated by acute intracerebral hemorrhage (ICH) and bilateral adrenal hemorrhage. In the setting of worsening thrombocytopenia, the risk of expansion of ICH and additional thrombotic events is concerning; hence, we employed plasmapheresis to reduce... | 25,124,104 | [
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[Air pollution and respiratory illness in children aged less than 5 years-old in Bogotá, 2007]. | Determining the relationship between indoor and outdoor air pollution caused by particulate matter PM10 and respiratory symptoms in children aged younger than 5 years-old in three locations in Bogota. This was a cohort study, involving 315 children in kindergartens located in the area of greatest exposure to PM10, and ... | 25,124,123 | [
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Effect of biomass smoke on chronic obstructive pulmonary disease in rural localities of Colombia. | The aim of this study was to assess the differences associated to the change of biofuel used to cook as a way to estimate the proportion of respiratory abnormalities of respiratory function associated to biomass exposure. A cross-sectional study was designed to evaluate the respiratory function through spirometry in su... | 25,124,130 | [
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Pain and inflammation in hidradenitis suppurativa correspond to morphological changes identified by high-frequency ultrasound. | Hidradenitis suppurativa (HS) is an inflammatory skin disease with a chronic intermittent course. The current classification systems used to categorize disease severity provide limited insight into the degree of inflammation and pain, which are key symptoms of the disease. We sought to investigate the correlation and v... | 25,124,135 | [
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Comparison of the microbiological quality of environmentally friendly and conventionally grown vegetables sold at retail markets in Korea. | Fresh produce is usually eaten raw without cooking or heating, which may increase the probability of foodborne infection. The microbiological quality of 11 types of fresh, raw vegetables (romaine lettuce, sesame leaves, crown daisy, garlic chives, iceberg lettuce, cabbage, broccoli, leek, chili pepper, capsicum, and zu... | 25,124,136 | [
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Optimizing oxygen delivery in the critically ill: the utility of lactate and central venous oxygen saturation (ScvO2) as a roadmap of resuscitation in shock. | Resuscitation of any critically ill patient is aimed at restoration of oxygen delivery to maintain aerobic metabolism. Thus, "endpoints" of resuscitation have been sought after as a measure of evaluating the adequacy of resuscitation. This review article describes the most commonly used endpoints, central venous oxygen... | 25,124,137 | [
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Entrustable professional activities: making sense of the emergency medicine milestones. | The Next Accreditation System (NAS) is being implemented by the Accreditation Council for Graduate Medical Education with seven specialties, including Emergency Medicine (EM), which began in July 2013. The NAS represents a more structured method of accreditation, with dependence on outcomes and less emphasis on educati... | 25,124,138 | [
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Expression of microRNA miR-126 and miR-200c is associated with prognosis in patients with non-small cell lung cancer. | MicroRNAs (miRNAs) are short non-coding RNAs that exert a critical influence on tumorigenesis through post-transcriptional modification and are considered to be potential biomarkers for the diagnosis or prognosis of various cancers. Although several miRNAs have been proposed as relevant biomarkers for non-small cell lu... | 25,124,149 | [
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High users of emergency departments in Quebec among patients with both schizophrenia and a substance use disorder. | The study assessed factors associated over time with high use of emergency departments by patients in Quebec who had schizophrenia and a co-occurring substance use disorder. The cohort study included 2,921 patients who received a diagnosis of schizophrenia in 2006 and had at least one emergency department visit during ... | 25,124,150 | [
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NIR spectroscopic method for the in-line moisture assessment during drying in a six-segmented fluid bed dryer of a continuous tablet production line: Validation of quantifying abilities and uncertainty assessment. | This study focuses on the thorough validation of an in-line NIR based moisture quantification method in the six-segmented fluid bed dryer of a continuous from-powder-to-tablet manufacturing line (ConsiGma™ 25, GEA Pharma Systems nv, Wommelgem, Belgium). The moisture assessment ability of an FT-NIR spectrometer (Matrix™... | 25,124,155 | [
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Flow cytometric enumeration of bacteria using TO-PRO®-3 iodide as a single-stain viability dye. | Quantification of bacteria using conventional viable plate counting (VPC) is labor-intensive and time-consuming. Flow cytometry (FCM) can be proposed as a faster alternative. This study aimed to develop a flow cytometric, single-stain approach using TO-PRO®-3 iodide (TP3) for the quantification of Staphylococcus aureus... | 25,124,156 | [
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Mental health/illness and prisons as place: frontline clinicians׳ perspectives of mental health work in a penal setting. | This article takes mental health and prisons as its two foci. It explores the links between social and structural aspects of the penal setting, the provision of mental healthcare in prisons, and mental health work in this environment. This analysis utilises qualitative interview data from prison-based fieldwork underta... | 25,124,166 | [
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Ocular pterygium--digital keloid dysplasia. | We describe an adolescent Peruvian male with marked, aggressive ingrowth of conjunctiva (pterygium-like) over the cornea associated with keloid formation on his distal limbs. He has in addition camptodactyly of all fingers and to some extent of his toes, and unusual skin pigmentations. He resembles an earlier described... | 25,124,224 | [
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Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators. | Pro-resolving lipid mediators are a class of endogenously synthesized molecules derived from different fatty acids, such as arachidonic, docosahexaenoic or eicosapentaenoic acid, which are derived into four different product families: lipoxins, resolvins, maresins and protectins. For quantitation of these compounds, a ... | 25,124,229 | [
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A study on the mechanism by which MDMA protects against dopaminergic dysfunction after minimal traumatic brain injury (mTBI) in mice. | Driving under methylenedioxymethamphetamine (MDMA) influence increases the risk of being involved in a car accident, which in turn can lead to traumatic brain injury. The behavioral deficits after traumatic brain injury (TBI) are closely connected to dopamine pathway dysregulation. We have previously demonstrated in mi... | 25,124,230 | [
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Equivalent input produces different output in the UniFrac significance test. | UniFrac is a well-known tool for comparing microbial communities and assessing statistically significant differences between communities. In this paper we identify a discrepancy in the UniFrac methodology that causes semantically equivalent inputs to produce different outputs in tests of statistical significance. The p... | 25,124,232 | [
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MOF-derived porous ZnO/ZnFe₂O₄/C octahedra with hollow interiors for high-rate lithium-ion batteries. | Novel porous ZnO/ZnFe2O4/C octahedra with hollow interiors are fabricated by a facile self-sacrificing template method involving the refluxing synthesis of hollow, metal-organic framework octahedra in solution and subsequent thermal annealing in N2 . When evaluated as an anode material for lithium-ion batteries, these ... | 25,124,234 | [
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[Evidence-based public health decision-making tools which can also be used for prioritising disease]. | He use of research-based evidence has been promoted during recent years, due to the increasing development of evidence-based medicine,and it has been reported that transferring the concept of "evidence-based" from clinical to public health practice has not been as straight forward as expected.Much research-based eviden... | 25,124,245 | [
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[The background, development and perspectives of modern epidemiology]. | Epidemiology is an ongoing discipline (i.e. still being constructed) and many of the foundations of the theory and methods now in use were mostly developed during the second half of the twentieth century, arising from what is known today as "modern epidemiology". This paper summary the history and main ideas which guid... | 25,124,246 | [
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Preparation of thermally stable microcapsules with a chitosan-silica hybrid. | Addition of microcapsules with a high dielectric constant and low specific heat capacity to a battered layer was designed to create a higher temperature in the crust than in the prefried fish nuggets to prevent the water vapor in the fish nuggets from migrating to the crust during microwave heating. Therefore, chitosan... | 25,124,256 | [
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A therapeutic workplace for the long-term treatment of drug addiction and unemployment: eight-year outcomes of a social business intervention. | This study evaluated the long-term effects of a therapeutic workplace social business on drug abstinence and employment. Pregnant and postpartum women (N = 40) enrolled in methadone treatment were randomly assigned to a therapeutic workplace or usual care control group. Therapeutic workplace participants could work wee... | 25,124,257 | [
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Using electronic health record data to evaluate preventive service utilization among uninsured safety net patients. | This study compared the preventive service utilization of uninsured patients receiving care at Oregon community health centers (CHCs) in 2008 through 2011 with that of continuously insured patients at the same CHCs in the same period, using electronic health record (EHR) data. We performed a retrospective cohort analys... | 25,124,279 | [
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The cost-effectiveness of installing sidewalks to increase levels of transport-walking and health. | This study investigated the cost-effectiveness of installing sidewalks to increase levels of transport-walking. Secondary analysis using logistic regression established the association of sidewalks with transport-walking using two transport-walking thresholds of 150 and 60 min/week using Western Australian data (n=1394... | 25,124,280 | [
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The ability to suppress macrophage-mediated inflammation in orbital fat stem cells is controlled by miR-671-5p. | Our previous works demonstrated that systemic orbital fat-derived stem cell (OFSC) transplantation was effective in ameliorating lipopolysaccharide (LPS)-induced extensive acute lung injury (ALI) in vivo mainly through paracrine regulation of macrophage-mediated cytokine-storm. In this study, we explore the molecular m... | 25,124,290 | [
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Perihilar cholangiocarcinoma: paradigms of surgical management. | Cholangiocarcinoma is a lethal disease with increasing incidence worldwide. Perihilar cholangiocarcinoma represents the most common type of cholangiocarcinoma. Despite major development on surgical strategies over the past 20 years, the 5-year survival rate after surgery has remained below 40%, often in the vicinity of... | 25,124,294 | [
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Smoking, MATRICS consensus cognitive battery and P50 sensory gating in a Han Chinese population. | The effects of smoking on cognitive performance have long been studied, with mixed results. P50 sensory gating has been used as endophenotype for studying nicotinic systems genetics, and P50 gating deficits have been reported to be a sensitive biomarker for cognitive impairment in schizophrenia. This study examined the... | 25,124,304 | [
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Oxidative modification, inflammation and amyloid in the normal and diabetic cat pancreas. | The pathogenesis of β-cell dysfunction leading to pancreatic β-cell failure seen in type 2 diabetes mellitus is incompletely understood. Pancreatic tissues were collected from nine control cats and nine diabetic cats and labelled immunohistochemically to examine expression of interleukin (IL)-1β, insulin, islet amyloid... | 25,124,331 | [
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Comparison of the ocular characteristics of anterior uveitis caused by herpes simplex virus, varicella-zoster virus, and cytomegalovirus. | To compare the clinical characteristics of anterior uveitis (AU) caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), or cytomegalovirus (CMV). The medical records were reviewed of 46 patients whose diagnoses were based on their clinical characteristics [e.g., unilateral involvement, presence of keratic ... | 25,124,341 | [
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Occupational exposure to air pollutants: particulate matter and respiratory symptoms affecting traffic-police in Bogotá. | Quantifying personal exposure to particles less than 10 micrometres in diameter (PM10) and determining the prevalence of respiratory symptoms in traffic-police officers working in Bogotá's metropolitan area. This was a cross-sectional study of 574 traffic-police officers divided into two groups (477 traffic-police and ... | 25,124,352 | [
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Improvement of arterial oxygenation in free-ranging moose (Alces alces) immobilized with etorphine-acepromazine-xylazine. | The effect of intranasal oxygen and/or early reversal of xylazine with atipamezole on arterial oxygenation in free-ranging moose (Alces alces) immobilized with etorphine-acepromazine-xylazine with a cross-sectional clinical study on 33 adult moose was evaluated. Before treatment the mean±SD (range) partial pressure of ... | 25,124,367 | [
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-0.2118561,
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0.0191151,
-0.03822369,
-0.5091406,
0.07220944,
0.10035,
0.3079986,
0.07707572,
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0.1567139,
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0.03146764,
0.05598042,
0.2417511,
-0.272056,
-0.04627262,
-0.1939044,
... |
Stress, Drugs, and Alcohol Use Among Health Care Professional Students: A Focus on Prescription Stimulants. | To contrast the characteristics of pharmacy, medicine, and physician assistant (PA) students regarding the prevalence of drug, alcohol, and tobacco use and to identify risk factors associated with prescription stimulant use. Five hundred eighty nine students were recruited to complete a 50-item Web-based survey. Demogr... | 25,124,376 | [
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-... |
Methylenetetrahydrofolate reductase C667T polymorphism is associated with increased risk of coronary artery disease in a Chinese population. | Coronary artery disease (CAD) is a complex disease resulting from a combination of environmental and genetic factors. We hypothesized that polymorphisms in methylenetetrahydrofolate reductase (MTHFR) rs1801133 C/T, matrix metalloproteinases (MMPs)-2, tumour necrosis factor (TNF)-α, macrophage migration inhibitory facto... | 25,124,382 | [
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0.2691204,
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... |
Water engineering. Reducing sewer corrosion through integrated urban water management. | Sewer systems are among the most critical infrastructure assets for modern urban societies and provide essential human health protection. Sulfide-induced concrete sewer corrosion costs billions of dollars annually and has been identified as a main cause of global sewer deterioration. We performed a 2-year sampling camp... | 25,124,439 | [
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0.... |
Place cells. Large environments reveal the statistical structure governing hippocampal representations. | The rules governing the formation of spatial maps in the hippocampus have not been determined. We investigated the large-scale structure of place field activity by recording hippocampal neurons in rats exploring a previously unencountered 48-meter-long track. Single-cell and population activities were well described by... | 25,124,440 | [
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Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice. | Hearing relies on the mechanosensory inner and outer hair cells (OHCs) of the organ of Corti, which convert mechanical deflections of their actin-rich stereociliary bundles into electrochemical signals. Several actin-associated proteins are essential for stereocilia formation and maintenance, and their absence leads to... | 25,124,451 | [
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0.1065263,
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Randomized controlled trial of Qigong/Tai Chi Easy on cancer-related fatigue in breast cancer survivors. | Many breast cancer survivors experience fatigue, mood, and sleep disturbances. This study aims to compare a meditative movement practice, Qigong/Tai Chi Easy (QG/TCE) with sham Qigong (SQG), testing effects of meditation/breath aspects of QG/TCE on breast cancer survivors' persistent fatigue and other symptoms. This do... | 25,124,456 | [
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0.3690511,
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Clinical significance of surgical resection for the recurrence of esophageal cancer after radical esophagectomy. | This study aimed to clarify the clinical significance of surgical resection for recurrent lesions after esophagectomy for esophageal cancer. Recurrence was detected in 113 of 365 consecutive patients who underwent surgical resection for esophageal cancer, and some treatment was performed for recurrence in 100 of the 11... | 25,124,469 | [
0.05346256,
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0.04158074,
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0.1938163,
0.3048865,
0.0522023,
0.4498874,
-0.0211748... |
Implicit affective evaluation bias in hypochondriasis: findings from the Affect Misattribution Procedure. | Cognitive theories of hypochondriasis (HYP) suggest that catastrophic misinterpretations of benign body sensations are a core feature for the maintenance of the disorder. There is tentative support from an analog sample that the interpretation of illness-related information also involves an implicit affective component... | 25,124,504 | [
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0.1294112,
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0.1848281,
0.2464907,
-0.107... |
Peeking into the black box: mechanisms of action for anger management treatment. | We investigated potential mechanisms of action for anger symptom reductions, specifically, the roles of anger regulation skills and therapeutic alliance on changes in anger symptoms, following group anger management treatment (AMT) among combat veterans with posttraumatic stress disorder (PTSD). Data were drawn from a ... | 25,124,505 | [
0.05009356,
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0.2728427,
0.465997,
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0.2023412,
0.110664,
-0.2139807... |
Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells. | Liver X receptors (LXRs) have been proposed to have some anticancer properties, through molecular mechanisms that remain elusive. Here we report for the first time that LXR ligands induce caspase-1-dependent cell death of colon cancer cells. Caspase-1 activation requires Nod-like-receptor pyrin domain containing 3 (NLR... | 25,124,554 | [
-0.2584983,
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0.243279,
0.2978727,
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... |
Review of the molecular pathogenesis of osteosarcoma. | Treating the osteosarcoma (OSA) remains a challenge. Current strategies focus on the primary tumor and have limited efficacy for metastatic OSA. A better understanding of the OSA pathogenesis may provide a rational basis for innovative treatment strategies especially for metastases. The aim of this review is to give an... | 25,124,559 | [
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0.2033114,
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0.2020232,
0.1296041,
0.04052648,
-0.2547801... |
Upregulation of STK15 in esophageal squamous cell carcinomas in a Mongolian population. | The STK15 gene located on chromosome 20q13.2 encodes a centrosome-associated kinase critical for regulated chromosome segregation and cytokinesis. Recent studies have demonstrated STK15 to be significantly associated with many tumors, with aberrant expression obseved in many human malignancies. The purpose of this stud... | 25,124,567 | [
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0.1577148,
0.1684772,
0.6296805,
0.01689274,
0.... |
Impact of prognostic factors on survival rates in patients with ovarian carcinoma. | The aim of the present study was to invesitigate the impact of significant clinico-pathological prognostic factors on survival rates and to identify factors predictive of poor outcome in patients with ovarian carcinoma. A retrospective chart review of 74 women with pathologically proven ovarian carcinoma who were treat... | 25,124,578 | [
0.1928808,
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0.2089583,
0.1767732,
0.1499465,
0.07645386,
0.2476025,
-0.07214919,
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... |
Elevated serum ferritin levels in patients with hematologic malignancies. | To retrospectively analyze variability and clinical significance of serum ferritin levels in Chinese patients with hematologic malignancies. Serum ferritin were measured by radioimmunoassay, using a kit produced by the Beijing Institute of Atomic Energy. Patients with hematologic malignancies, and treated in the Depart... | 25,124,580 | [
-0.1108025,
0.1687332,
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0.03813163,
0.1321962,
-0.4463944,
... |
Combined detection of CEA, CA 19-9, CA 242 and CA 50 in the diagnosis and prognosis of resectable gastric cancer. | Our aim was to investigate the value of combined detection of serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA 242 and CA 50 in diagnosis and assessment of prognosis in consecutive gastric cancer patients. Clinical data including preoperative serum CEA, CA 19-9, CA 242, and CA 50 values and info... | 25,124,614 | [
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0... |
Preliminary evaluation of the in vitro efficacy of 1, 2-di (quinazolin-4-yl) diselane against SiHa cervical cancer cells. | Cervical cancer is one the most common malignancies among females. In recent years, its incidence rate has shown a rising trend in some countries so that development of anticancer drugs for cervical cancer is an urgent priority. In our recent anticancer drug discovery screen, 1, 2-di (quinazolin-4-yl)diselane (LG003) w... | 25,124,615 | [
-0.2027813,
-0.1004155,
0.04807485,
0.1320237,
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0.2487838,
0.4457869,
0.6718409,
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... |
Descriptive report on pattern of variation in cancer cases within selected ethnic groups in Kamrup Urban District of Assam, 2009-2011. | The global burden of cancer is continuously increasing. According to recent report of the National Cancer Registry Programme (NCRP) on time trends it is estimated that future burden of cancer cases for India in 2020 will be 1,320,928. It is well known that knowledge of the incidence of cancer is a fundamental requireme... | 25,124,629 | [
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0.4695424,
0.2637395,
0.006184255,
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0.0110068,
0.3791777,
-0.08824076,
0... |
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