title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Inhibition of U(VI) reduction by synthetic and natural pyrite. | Reductive precipitation is an effective method of attenuating the mobility of uranium (U) in subsurface environments. The reduction of U(VI) by synthetic and naturally occurring pyrite was investigated at pH 3.0-9.5. In contrast to thermodynamic calculations that were used to predict UO2(s) precipitation, a mixed U(IV)... | 25,148,405 | [
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Accelerated photoaging induced by voriconazole treated with Q-switched Nd:YAG laser: case report and review of the literature. | Voriconazole is an antifungal agent mainly used against aspergillosis. Given its wide spectrum of action and limited adverse effects, it has replaced amphotericin B as the drug of choice in the prophylactic treatment of immunocompromised patients. Several adverse effects are caused by this drug with dermatological reac... | 25,148,408 | [
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Individual differences in impulsivity predict head motion during magnetic resonance imaging. | Magnetic resonance imaging (MRI) provides valuable data for understanding the human mind and brain disorders, but in-scanner head motion introduces systematic and spurious biases. For example, differences in MRI measures (e.g., network strength, white matter integrity) between patient and control groups may be due to t... | 25,148,416 | [
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Alemtuzumab for the treatment of relapsing-remitting multiple sclerosis: a review of its clinical pharmacology, efficacy and safety. | Multiple sclerosis (MS) is an inflammatory condition of the CNS presumably induced by an environmental trigger(s) in a genetically susceptible individual. Inflammation is prominent and most susceptible to intervention early in MS, so early treatment with disease-modifying therapies is recommended to reduce relapses and... | 25,148,422 | [
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Infections in the immunosuppressed host. | The interaction between host immunity and infections in the context of a suppressed immune system presents an opportunity to study the interaction of colonization and infection with the development of acute and chronic pulmonary morbidity and mortality. This article summarizes presentations at the Pittsburgh Internatio... | 25,148,427 | [
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Infections in "noninfectious" lung diseases. | Many chronic pulmonary diseases, including those that are not primarily infectious in etiology, have some aspects of their pathogenesis that are influenced by infectious organisms. Microorganisms may contribute to chronic lung diseases, either directly (i.e., overt infection) or indirectly, via the amplification of inf... | 25,148,428 | [
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Managing hypertension in patients with chronic kidney disease. | Chronic kidney disease (CKD) and hypertension are intrinsically linked. Although 59% of the US population will be diagnosed with CKD during their lifetimes, mortality is usually due to a cardiovascular event. Sodium restriction and a combination of a renin-angiotensin-aldosterone medication and a calcium channel blocke... | 25,148,442 | [
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Similar hormonal stress and tissue damage in response to National Collegiate Athletic Association Division I football games played in two consecutive seasons. | The recovery process from a college football game has been studied, yet the stability of such findings year to year in the same players remains unclear. The purpose of this study was to examine the same players' biochemical recovery process in 2 consecutive seasons to a National Collegiate Athletic Association (NCAA) D... | 25,148,465 | [
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Low genetic diversity in Melanaphis sacchari aphid populations at the worldwide scale. | Numerous studies have examined the genetic diversity and genetic structure of invading species, with contrasting results concerning the relative roles of genetic diversity and phenotypic plasticity in the success of introduced populations. Increasing evidence shows that asexual lineages of aphids are able to occupy a w... | 25,148,510 | [
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Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. | The continued proliferation of malaria throughout temperate and tropical regions of the world has promoted a push for more efficacious treatments to combat the disease. Unfortunately, more recent remedies such as artemisinin combination therapies have been rendered less effective due to developing parasite resistance, ... | 25,148,516 | [
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Calcium homeostasis in myogenic differentiation factor 1 (MyoD)-transformed, virally-transduced, skin-derived equine myotubes. | Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malignant hyperthermia, central core disease, multiminicore disease and cer... | 25,148,524 | [
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Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity. | DNA lesion bypass polymerases process different lesions with varying fidelities, but the structural, dynamic, and mechanistic origins of this phenomenon remain poorly understood. Human DNA polymerase κ (Polκ), a member of the Y family of lesion bypass polymerases, is specialized to bypass bulky DNA minor groove lesions... | 25,148,552 | [
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Working with a domestic assessment system to estimate the need of support and care of elderly and disabled persons: results from field studies. | This article describes the results of field studies performed over a period between five months and 24 months. The objectives of these studies were to collect long-term real-life data to evaluate how these data can be mapped to items on standardized assessment tests and which presentation method is most suitable to inf... | 25,148,558 | [
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Performing gait analysis within the timed up & go assessment test: comparison of aTUG to a marker-based tracking system. | Results from a technical validation of the aTUG (ambient Timed Up & Go) system are presented. The approach's gait analysis capabilities were compared to a gold standard: SIMI Motion, a marker-based motion tracking system. Seven people participated and computation of step length and step duration happened with a med... | 25,148,559 | [
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Business model for sensor-based fall recognition systems. | AAL systems require, in addition to sophisticated and reliable technology, adequate business models for their launch and sustainable establishment. This paper presents the basic features of alternative business models for a sensor-based fall recognition system which was developed within the context of the "Lower Saxony... | 25,148,563 | [
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Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. | The management of melanoma has evolved owing to improved understanding of its molecular drivers. To augment the current understanding of the prevalence, patterns, and associations of mutations in this disease, the results of clinical testing of 699 advanced melanoma patients using a pan-cancer next-generation sequencin... | 25,148,578 | [
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Identification of p38β as a therapeutic target for the treatment of Sézary syndrome. | Cutaneous T-cell lymphomas (CTCLs) represent a group of hematopoietic malignancies that home to the skin and have no known molecular basis for disease pathogenesis. Sézary syndrome (SS) is the leukemic variant of CTCL. Currently, CTCL is incurable, highlighting the need for new therapeutic modalities. We have previousl... | 25,148,579 | [
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Household-level spatiotemporal patterns of incidence of cholera, Haiti, 2011. | A cholera outbreak began in Haiti during October, 2010. Spatiotemporal patterns of household-level cholera in Ouest Department showed that the initial clusters tended to follow major roadways; subsequent clusters occurred further inland. Our data highlight transmission pathway complexities and the need for case and hou... | 25,148,590 | [
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Promiscuity and selectivity in covalent enzyme inhibition: a systematic study of electrophilic fragments. | Covalent ligand-target interactions offer significant pharmacological advantages. However, off-target reactivity of the reactive groups, which usually have electrophilic properties, must be minimized, and the selectivity of irreversible inhibitors is a crucial requirement. We therefore performed a systematic study to d... | 25,148,591 | [
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Structure-based virtual screening of the nociceptin receptor: hybrid docking and shape-based approaches for improved hit identification. | The antagonist-bound crystal structure of the nociceptin receptor (NOP), from the opioid receptor family, was recently reported along with those of the other opioid receptors bound to opioid antagonists. We recently reported the first homology model of the 'active-state' of the NOP receptor, which when docked with 'ago... | 25,148,595 | [
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Recent approaches of lipid-based delivery system for lymphatic targeting via oral route. | Lymphatic system is a key target in research field due to its distinctive makeup and huge contributing functions within the body. Intestinal lymphatic drug transport (chylomicron pathway) is intensely described in research field till date because it is considered to be the best for improving oral drug delivery by avoid... | 25,148,607 | [
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Congenital isolated aplasia of lower lateral cartilage and reconstruction using dorsal hump material. | Congenital nasal abnormalities are very rare in the literature. There are 3 reported cases of isolated partial lower lateral cartilage defects. In this article, we report the case of a patient with congenital complete absence of the lower lateral cartilage. The patient had severe external nasal valve dysfunction and a ... | 25,148,619 | [
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Endonasal endoscopic excision of a rare tumor: nasal bone osteoid osteoma. | Osteomas are slow-growing, benign tumors that frequently occur in paranasal areas; are detected by their symptoms, depending on their location and size, or incidentally on radiologic examination; and rarely arise from the nasal bone. We present an isolated nasal bone osteoma--which has not, to our knowledge, been repor... | 25,148,628 | [
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Dental trauma: knowledge and attitudes of community health workers. | The international literature emphasizes the importance of evaluating the knowledge of different groups such as teachers, students, dentists, physicians, parents, and athletes regarding dental injuries. In Brazil, community health workers are professionals who can reach a wide variety of people and who have a marked inf... | 25,148,633 | [
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Thornwaldt cysts. | Thornwaldt cysts are rare and benign congenital cysts in the region of the pharyngeal bursa, formed by a communication between the notochord and the nasopharyngeal endoderm. They result from a mechanical obstruction, inflammation, or abscess of the pharyngeal bursa. They are superficial to the superior constrictor musc... | 25,148,637 | [
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Joint segmentation of images and scanned point cloud in large-scale street scenes with low-annotation cost. | We propose a novel method for the parsing of images and scanned point cloud in large-scale street environment. The proposed method significantly reduces the intensive labeling cost in previous works by automatically generating training data from the input data. The automatic generation of training data begins with the ... | 25,148,662 | [
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End-point impedance measurements across dominant and nondominant hands and robotic assistance with directional damping. | The goal of this paper is to perform end-point impedance measurements across dominant and nondominant hands while doing airbrush painting and to use the results for developing a robotic assistance scheme. We study airbrush painting because it resembles in many ways manual welding, a standard industrial task. The experi... | 25,148,680 | [
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Tensile strength of carbyne chains in varied chemical environments and structural lengths. | Carbyne and carbyne-based low-dimensional structures are promising for several applications including ultra-compact circuits and purification devices. Designing any applied carbyne-based structure requires a fundamental understanding of the mechanical strength of carbyne chains with different lengths at different tempe... | 25,148,690 | [
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AUF1 is recruited to the stress granules induced by coxsackievirus B3. | Stress granules (SGs) are cytoplasmic granules that are formed in cells when stress occurs. In this study, we found that SGs formed in cells infected with coxsackievirus B3 (CVB3), evidenced with the co-localization of some accepted SG markers in the viral infection-induced granules. We further discovered that adenosin... | 25,148,713 | [
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Effects of different inoculation routes on the parasitic sites of Cryptosporidium baileyi infection in chickens. | Cryptosporidiosis is prevalent in domesticated, caged, and wild birds. Cryptosporidium baileyi, an ascendant species of avian Cryptosporidium, is an important pathogen. It causes respiratory disease in chickens, especially chickens younger than 50 days. In this study, SEM, histological, semi-quantitative PCR, and neste... | 25,148,714 | [
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[Process, procedure and requested conditions for academic appointment in anesthesia and intensive care]. | Since several decades, anesthesia care and intensive care, as well, are engaged in the way of excellence in clinical care and research. This requirement is also applied for the selection of professor and academic workers. The goals of this article are twice: first to diffuse this knowledge at the medical community and ... | 25,148,717 | [
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Sustained and controlled release of lipophilic drugs from a self-assembling amphiphilic peptide hydrogel. | Materials which undergo self-assembly to form supramolecular structures can provide alternative strategies to drug loading problems in controlled release application. RADA 16 is a simple and versatile self-assembling peptide with a designed structure formed of two distinct surfaces, one hydrophilic and one hydrophobic ... | 25,148,727 | [
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Determining delayed admission to intensive care unit for mechanically ventilated patients in the emergency department. | The adverse effects of delayed admission to the intensive care unit (ICU) have been recognized in previous studies. However, the definitions of delayed admission varies across studies. This study proposed a model to define "delayed admission", and explored the effect of ICU-waiting time on patients' outcome. This retro... | 25,148,726 | [
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Interaction of solutions containing phenothiazines exposed to laser radiation with materials surfaces, in view of biomedical applications. | Phenothiazine drugs - chlorpromazine (CPZ), promazine (PZ) and promethazine (PMZ) - were exposed to 266 nm (fourth harmonic of the Nd:YAG pulsed laser radiation) in order to be modified at molecular level and to produce an enhancement of their antibacterial activity. The irradiated samples were analysed by several meth... | 25,148,730 | [
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Methodology for image-based reconstruction of ventricular geometry for patient-specific modeling of cardiac electrophysiology. | Patient-specific modeling of ventricular electrophysiology requires an interpolated reconstruction of the 3-dimensional (3D) geometry of the patient ventricles from the low-resolution (Lo-res) clinical images. The goal of this study was to implement a processing pipeline for obtaining the interpolated reconstruction, a... | 25,148,771 | [
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Community structure and distribution of planktonic ammonia-oxidizing archaea and bacteria in the Dongjiang River, China. | Ammonia-oxidizing archaea (AOA) and bacteria (AOB) are widely distributed in the natural environment and play crucial roles in the nitrification process and the removal of nitrogen (N). Although planktonic microbial community plays an important role in river biogeochemical cycles, few studies have attempted to address ... | 25,148,780 | [
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Alexithymia impact on type 1 and type 2 diabetes: a case-control study. | This paper focus on studying the prevalence of alexithymia in diabetes type 1 and type 2 and its impact on diabetes's clinical and therapeutic characteristics. We also studied the relationship between alexithymia and emotional disorders in diabetics. The study involved a sample of 125 diabetic patients, among whom 50 h... | 25,148,784 | [
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Oxford classification of IgA nephropathy is applicable to predict long-term outcomes of Henoch-Schönlein purpura nephritis. | Henoch-Schönlein purpura nephritis and IgA nephropathy are currently considered to be different clinical presentations of the same disease. There is need for a reliable proven, morphologic classification that can help clinicians more accurately formulate treatment strategies for patients with Henoch-Schönlein purpura n... | 25,148,806 | [
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Incision Planning in Thyroid Compartment Surgery: Getting it Perfect. | This study evaluated changes in thyroid compartment incision site locations with patient positioning to define a reliable method for placing the scar in the optimal vertical location. The optimal incision location was marked with the patient sitting upright before surgery. The distance from the sternal notch to this ma... | 25,148,816 | [
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Predictions of heading date in bread wheat (Triticum aestivum L.) using QTL-based parameters of an ecophysiological model. | Prediction of wheat phenology facilitates the selection of cultivars with specific adaptations to a particular environment. However, while QTL analysis for heading date can identify major genes controlling phenology, the results are limited to the environments and genotypes tested. Moreover, while ecophysiological mode... | 25,148,833 | [
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Total alkaloids of Rubus alceifolius Poir shows anti-angiogenic activity in vivo and in vitro. | Total alkaloids is an active ingredient of the natural plant Rubus alceifolius Poir, commonly used for the treatment of various cancers. Antitumor effects may be mediated through anti-angiogenic mechanisms. As such, the goal of the present study was to investigate and evaluate the effect of total alkaloids in Rubus alc... | 25,148,840 | [
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Relationship between neighborhood walkability and older adults' physical activity: results from the Belgian Environmental Physical Activity Study in Seniors (BEPAS Seniors). | Adequate knowledge on environmental correlates of physical activity (PA) in older adults is needed to develop effective health promotion initiatives. However, research in this age group is scarce and most existing studies were conducted in North America. The present study aimed to examine relationships between GIS-base... | 25,148,845 | [
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Apolipoprotein E synthesized by adipocyte and apolipoprotein E carried on lipoproteins modulate adipocyte triglyceride content. | Excessive energy storage of adipose tissue makes contribution to the occurrence and progression of obesity, which accompanies with multiple adverse complications, such as metabolic syndrome, cardiovascular diseases. It is well known that apolipoprotein E, as a component of lipoproteins, performs a key role in maintaini... | 25,148,848 | [
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The neuroendocrinology of social isolation. | Social isolation has been recognized as a major risk factor for morbidity and mortality in humans for more than a quarter of a century. Although the focus of research has been on objective social roles and health behavior, the brain is the key organ for forming, monitoring, maintaining, repairing, and replacing salutar... | 25,148,851 | [
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The hidden efficacy of interventions: gene×environment experiments from a differential susceptibility perspective. | The efficacy of interventions might be underestimated or even go undetected as a main effect when it is hidden in gene-by-environment (G×E) interactions. This review moves beyond the problems thwarting correlational G×E research to propose genetic differential susceptibility experiments. G×E experiments can test the br... | 25,148,854 | [
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Cytokine response in peripheral blood indicates different pathophysiological mechanisms behind anastomotic leakage after low anterior resection: a pilot study. | Anastomotic leakage (AL) after rectosigmoid resection is a serious complication associated with high morbidity and mortality. This case-control pilot study investigated the changes in blood concentration of 10 different cytokines and 2 complement factors in relation to symptomatic AL after low anterior resection for re... | 25,148,865 | [
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[Prediction of psychoses]. | The worldwide established early detection and prevention centers for psychosis follow the modern program of predictive, preventive and personalized medicine. If primary prevention is to succeed, the individual risk of the disease has to be estimated correctly and the psychosis onset has to be accurately predicted. Acco... | 25,148,868 | [
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Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function. | Alcoholic liver disease has been clinically well described, but the molecular mechanisms leading to hepatotoxicity have not been fully elucidated. Previously, we determined that microtubules are hyperacetylated and more stable in ethanol-treated WIF-B cells, VL-17A cells, liver slices, and in livers from ethanol-fed ra... | 25,148,871 | [
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Platelet-derived growth factor blockade on cardiac remodeling following infarction. | Cardiac repair and remodeling occur following myocardial infarction (MI). Our previous study demonstrated that platelet-derived growth factor (PDGF)-A/-D and PDGF receptors (PDGFR) are increased in the infarcted heart, with cells expressing PDGFR primarily endothelial and fibroblast-like cells. In the present study, we... | 25,148,874 | [
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Long-term exercise in older adults: 4-year outcomes of music-based multitask training. | Prospective controlled evidence supporting the efficacy of long-term exercise to prevent physical decline and reduce falls in old age is lacking. The present study aimed to assess the effects of long-term music-based multitask exercise (i.e., Jaques-Dalcroze eurhythmics) on physical function and fall risk in older adul... | 25,148,876 | [
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Isolation and characterization of novel Glu-St1 alleles from Pseudoroegneria spicata and Pd. strigosa. | Pseudoroegneria is a small genus of the Triticeae tribe; its St genome is present in over half of allopolyploid Triticeae species. The high molecular weight (HMW) subunits of glutenin (GS) encoded by the St genome are not well described. In this paper, we report the characterization of fourteen alleles of HMW-GS genes ... | 25,148,878 | [
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To worry or not to worry: breast cancer genetic counseling communication with low-income Latina immigrants. | The purpose of this pilot study was to describe communication practices during hereditary breast cancer genetic counseling (GC) with low-income immigrant Latina patients in a public hospital setting. We utilized qualitative ethnographic methods, including direct observation of GC appointments with Latina patients at a ... | 25,148,879 | [
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A miRNA-binding site single nucleotide polymorphism in the 3'-UTR region of the NOD2 gene is associated with colorectal cancer. | Colorectal cancer (CRC) is one of the common malignancies worldwide. Single nucleotide polymorphisms in miRNA-binding site on gene transcripts are reported to play important role in increased risk of CRC in different population. We performed a case-control study using 88 CRC patients and 88 non-cancer counterparts to e... | 25,148,897 | [
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Intima media thickness, pulse wave velocity, and flow mediated dilation. | The identification of vascular alterations at the sub-clinical, asymptomatic stages are potentially useful for screening, prevention and improvement of cardiovascular risk stratification beyond classical risk factors.Increased intima-media thickness of the common carotid artery is a well-known marker of early atheroscl... | 25,148,901 | [
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Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence. | Contrast-induced acute kidney injury is a common cause of iatrogenic acute kidney injury (AKI). Most of the published estimates of AKI after contrast use originate from the cardiac catheterization literature despite contrast-enhanced computed tomography (CT) scans being the more common setting for contrast use. This sy... | 25,148,933 | [
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The Clinical Implications of Transforming Growth Factor Beta in Pathological Grade and Prognosis of Glioma Patients: A Meta-Analysis. | The transforming growth factor beta (TGF-β) pathway plays a key role in oncogenesis of advanced cancers. However, the effects of TGF-β pathway on gliomas are still controversial. So, it is essential to conduct a meta-analysis to determine their correlations. Eligible studies were included, and then odds ratios (ORs), s... | 25,148,935 | [
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... |
CPuORF correlates with miRNA responsive elements on protein evolutionary rates. | miRNA is increasingly being recognized as a key regulator of metabolism in animals. A wealth of evidence has suggested that miRNA mainly binds 3' UTR of mRNA and modulates the cell activities via repressing the mRNA translation. However, as the translation initiates at 5' UTR, cis elements like upstream open reading fr... | 25,148,940 | [
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Multilocus typing of Cryptosporidium spp. and Giardia duodenalis from non-human primates in China. | Non-human primates (NHPs) are commonly infected with Cryptosporidium spp. and Giardia duodenalis. However, molecular characterisation of these pathogens from NHPs remains scarce. In this study, 2,660 specimens from 26 NHP species in China were examined and characterised by PCR amplification of 18S rRNA, 70kDa heat shoc... | 25,148,945 | [
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Method development by GC-ECD and HS-SPME-GC-MS for beer volatile analysis. | Two methods for the extraction, identification and quantification of the highest occurrence and lowest perception threshold off-flavours in fifteen different samples of Brazilian Pilsner beers were developed. For this purpose, headspace solid phase microextraction in combination with a gas chromatography coupled to a m... | 25,148,961 | [
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The intake of a hazelnut skin extract improves the plasma lipid profile and reduces the lithocholic/deoxycholic bile acid faecal ratio, a risk factor for colon cancer, in hamsters fed a high-fat diet. | The effects on lipid and glucose metabolism of a hazelnut skin extract (FIBEROX™) administrated during 8 weeks (HFD-FBX8w group) or during the last 4 weeks of the study (HFD-FBX4w group) to Golden Syrian hamsters fed a high-fat diet (HFD) for 8 weeks were investigated. FIBEROX™ consumption reversed the increase in tota... | 25,148,970 | [
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Chemical and sensory characterisation of Sangiovese red wines: comparison between biodynamic and organic management. | The effects of biodynamic production practices on composition and sensory attributes of Sangiovese wines were examined for 2 years (2009 and 2010) in a vineyard that was converted from organic (ORG) to biodynamic (BDN) viticulture. During the first year (2009), the BDN wines were characterised by low alcohol strength, ... | 25,148,971 | [
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Evaluation of anti-inflammatory activity and fast UHPLC-DAD-IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano). | Fresh cut vegetables represent a widely consumed food worldwide. Among these, lettuce (Lactuca sativa L.) is one of the most popular on the market. The growing interest for this "healthy" food is related to the content of bioactive compounds, especially polyphenols, that show many beneficial effects. In this study, we ... | 25,148,972 | [
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Quercetin-3-O-β-D-glucopyranoside, a dietary flavonoid, protects PC12 cells from H₂O₂-induced cytotoxicity through inhibition of reactive oxygen species. | Since flavonols are antioxidant agents, they could in principle, beneficially affect neurodegenerative diseases where reactive oxygen species are involved. Quercetin derivatives are the most abundant dietary flavonoids, and we have investigated the capacity of quercetin-3-O-β-d-glucopyranoside (Q3G) isolated from Echin... | 25,148,973 | [
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Preparation of organic tofu using organic compatible magnesium chloride incorporated with polysaccharide coagulants. | Organic tofu using organic compatible coagulants of magnesium chloride and three polysaccharides including carrageenan, guar gum and gum Arabic were generated. For MgCl2 coagulated tofu, carrageenan significantly increased the hardness from 969.5 g to 1210.5 g whereas guar gum (0.6g) decreased the hardness to 505.5 g. ... | 25,148,974 | [
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Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products. | In this study, fruit and vegetable wastes and by-products were tested for polyphenol content and their antioxidant activity. The highest content of polyphenols as assessed by the Folin-Ciocalteu assay was the hot-water extract of grape seed, followed by the ethanol extract of buckwheat hull. The highest antioxidant act... | 25,148,998 | [
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Olive oil pilot-production assisted by pulsed electric field: impact on extraction yield, chemical parameters and sensory properties. | The impact of the use of pulsed electric field (PEF) technology on Arroniz olive oil production in terms of extraction yield and chemical and sensory quality has been studied at pilot scale in an industrial oil mill. The application of a PEF treatment (2 kV/cm; 11.25 kJ/kg) to the olive paste significantly increased th... | 25,149,017 | [
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Does anxiety predict the use of urgent care by people with long term conditions? A systematic review with meta-analysis. | The role of anxiety in the use of urgent care in people with long term conditions is not fully understood. A systematic review was conducted with meta-analysis to examine the relationship between anxiety and future use of urgent healthcare among individuals with one of four long term conditions: diabetes; coronary hear... | 25,149,033 | [
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The actions of the renin-angiotensin system on cardiovascular and osmoregulatory function in embryonic chickens (Gallus gallus domesticus). | Using embryonic chickens (Gallus gallus domesticus), we examined the role of the renin-angiotensin system (RAS) in cardiovascular and osmotic homeostasis through chronic captopril, an angiotensin-converting enzyme (ACE) inhibitor. Captopril (5 mg kg⁻¹ embryo wet mass) or saline (control) was delivered via the egg air c... | 25,149,042 | [
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Enhanced lung epithelial specification of human induced pluripotent stem cells on decellularized lung matrix. | Whole-lung scaffolds can be created by perfusion decellularization of cadaveric donor lungs. The resulting matrices can then be recellularized to regenerate functional organs. This study evaluated the capacity of acellular lung scaffolds to support recellularization with lung progenitors derived from human induced plur... | 25,149,047 | [
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Clinical experience with the freedom SOLO stentless aortic valve in 277 consecutive patients. | The Sorin Freedom SOLO (FS) bovine pericardial stentless valve prosthesis is designed for supraannular, subcoronary implantation. We report our experience and results with 277 consecutively implanted FS bioprostheses. 277 patients (mean age, 74.2 ± 7.3 years; 139 (50.2%) female) underwent aortic valve replacement (AVR)... | 25,149,050 | [
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Characterization of the accessory protein ClpT1 from Arabidopsis thaliana: oligomerization status and interaction with Hsp100 chaperones. | The caseinolytic protease (Clp) is crucial for chloroplast biogenesis and proteostasis. The Arabidopsis Clp consists of two heptameric rings (P and R rings) assembled from nine distinct subunits. Hsp100 chaperones (ClpC1/2 and ClpD) are believed to dock to the axial pores of Clp and then transfer unfolded polypeptides ... | 25,149,061 | [
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Prevalence of patent Strongyloides westeri infections in Thoroughbred foals in 2014. | The prevalence of patent Strongyloides westeri infections was determined by examination for eggs in fecal samples collected from 513 Thoroughbred (TB) foals between February 25 and June 3, 2014. The study was conducted with 244 colts and 269 fillies from 11 well-managed farms in Central Kentucky. Foals ranged from 17 t... | 25,149,063 | [
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Astrocyte-derived retinoic acid: a novel regulator of blood-brain barrier function in multiple sclerosis. | Multiple sclerosis (MS) lesions are characterized by the presence of activated astrocytes, which are thought to actively take part in propagating lesion progression by secreting pro-inflammatory mediators. Conversely, reactive astrocytes may exert disease-dampening effects through the production of trophic factors and ... | 25,149,081 | [
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Unveiling the mysteries of the genetics of osteoporosis. | Osteoporosis is a common disease characterised by low bone mineral density and an increased risk of fragility fractures. We conducted a literature review of relevant studies relating to the genetics of osteoporosis. Family studies have revealed that bone density and fractures have a strong heritable component but envir... | 25,149,083 | [
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Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction. | Despite the increasing prevalence of heart failure with preserved ejection fraction (HFpEF) in humans, there remains no therapeutic options for HFpEF. Adiponectin, an adipocyte-derived cytokine, exerts cardioprotective actions, and its deficiency is implicated in the development of hypertension and HF with reduced ejec... | 25,149,095 | [
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Efficacy of a support group intervention on psychopathological characteristics among caregivers of psychotic patients. | Families of individuals with psychotic disorders are playing a major role in the care of their relatives, but report poorer physical competence, elevated symptoms of psychological distress and more psychopathological characteristics. To compare psychopathological characteristics demonstrated by caregivers of psychotic ... | 25,149,101 | [
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Isolated tympanic plate fracture frequency and its relationship to mandibular trauma. | This study evaluated the prevalence of isolated tympanic fractures and their correlation with mandibular fractures by using maxillofacial computed tomography (CT). We retrospectively evaluated the maxillofacial CT of 1590 patients who presented to our emergency department with maxillofacial trauma between December 2010... | 25,149,116 | [
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Musculoskeletal disorders among nurses compared with two other occupational groups. | There is a high incidence of low back pain (LBP) among nurses. However, few longitudinal studies have investigated musculoskeletal disorders (MSDs) at other anatomical sites in nurses. To describe the cumulative incidence and persistence/recurrence of MSDs of the low back, neck, shoulder, elbow, wrist/hand and knee amo... | 25,149,117 | [
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Expression and functional characterization of PGRP6 splice variants in grass carp Ctenopharyngodon idella. | Peptidoglycan recognition proteins (PGRPs), which are evolutionarily conserved pattern recognition receptors from insects to mammals, recognize bacterial PGN and function in antibacterial innate immunity. The existence of alternative splicing is a common feature for PGRP family. Here the splicing pattern from the splic... | 25,149,135 | [
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Evisceration as fetal destructive operation: an art revisited. | Fetal destructive operation is a vanishing art today. In an era of increasing cesarean deliveries it has become a historic event. Incidence of destructive operation has varied from various Indian hospitals 0.09-0.28%. Evisceration is one of the rarest of all destructive operations, performed in cases of cephalopelvic d... | 25,149,171 | [
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Advances in development of rechargeable mitochondrial antioxidants. | It has been about 15 years since the introduction of the rechargeable mitochondria-targeted antioxidants (RMA). Two major groups have been developing RMA of the MitoQ and SkQ types independently, and many additional trials have been done by other researchers. This has provided solid preclinical evidence of RMA efficacy... | 25,149,221 | [
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Sulfoxaflor and the sulfoximine insecticides: chemistry, mode of action and basis for efficacy on resistant insects. | The sulfoximines, as exemplified by sulfoxaflor ([N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-λ(4)-sulfanylidene] cyanamide] represent a new class of insecticides. Sulfoxaflor exhibits a high degree of efficacy against a wide range of sap-feeding insects, including those resistant to neonicotinoids and oth... | 25,149,228 | [
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Molecular architecture of photoreceptor phosphodiesterase elucidated by chemical cross-linking and integrative modeling. | Photoreceptor phosphodiesterase (PDE6) is the central effector enzyme in visual excitation pathway in rod and cone photoreceptors. Its tight regulation is essential for the speed, sensitivity, recovery and adaptation of visual detection. Although major steps in the PDE6 activation/deactivation pathway have been identif... | 25,149,264 | [
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0.09626033,
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0.157584,
0.2403253,
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0... |
Where there is a goal, there is a way: what, why and how the parieto-frontal mirror network can mediate imitative behaviours. | The relationships between mirror neurons (MNs) and motor imitation, and its clinical implications in autism spectrum disorder (ASD) have been widely investigated; however, the literature remains—at least partially—controversial. In this review we support a multi-level action understanding model focusing on the mirror-b... | 25,149,267 | [
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Mobile markerless augmented reality and its application in forensic medicine. | During autopsy, forensic pathologists today mostly rely on visible indication, tactile perception and experience to determine the cause of death. Although computed tomography (CT) data is often available for the bodies under examination, these data are rarely used due to the lack of radiological workstations in the pat... | 25,149,272 | [
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0.02855739,
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The hooded crow (Corvus cornix) as an environmental bioindicator species of heavy metal contamination. | This study aims to examine the possible presence of lead and cadmium in the liver and kidneys of hooded crows (Corvus cornix). Liver and kidneys of hooded crow carcasses were collected in Province of Cuneo (Piedmont, Italy) in order to detect lead and cadmium content. Significant differences were found in lead and cadm... | 25,149,280 | [
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Health risk assessments of lithium titanate nanoparticles in rat liver cell model for its safe applications in nanopharmacology and nanomedicine. | Due to their high chemical stability, lithium titanate (Li2TiO3) nanoparticles (LTT NPs) now are projected to be transferred into different nanotechnology areas like nano pharmacology and nano medicine. With the increased applications of LTT NPs for numerous purposes, the concerns about their potential human toxicity e... | 25,149,287 | [
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Methods of purification of CTL-derived exosomes. | Exosomes are membrane nanovesicles (approximately <120 nm in size) released by most, if not all, living cells and in particular by leukocytes. They originate within the endocytic compartment by invagination of the endosome membrane. Therefore, they have a different biogenesis and molecular composition than microvesi... | 25,149,305 | [
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Urinary biomarker investigation in children with Fabry disease using tandem mass spectrometry. | Fabry disease is an X-linked lysosomal storage disorder affecting both males and females with tremendous genotypic/phenotypic variability. Concentrations of globotriaosylceramide (Gb3), globotriaosylsphingosine (lyso-Gb3)/related analogues were investigated in pediatric and adult Fabry cohorts. The aims of this study w... | 25,149,322 | [
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Attenuation correction of (111)In planar images by use of dual energy, fundamental study by Monte Carlo simulation. | In this study, we devised and evaluated a method for attenuation correction of the hot spot in (111)In planar images. By use of the difference in transmittance between two energies (171 and 245 keV), the depth of the hot spot was calculated. Planar images of point sources in a numerical phantom (water) with depths from... | 25,149,323 | [
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0.0988323,
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0.101423,
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Estimation of dominance variance for live body weight in a crossbred population of pigs. | The objective of this study was to estimate the dominance variance for repeated live BW records in a crossbred population of pigs. Data were provided by the Walloon Pig Breeding Association and included 22,197 BW records of 2,999 crossbred Piétrain × Landrace K+ pigs from 50 to 210 d of age. The BW records were standar... | 25,149,333 | [
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0.009771358,
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0.08211753,
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Randomized clinical trial of continuous femoral nerve block combined with sciatic nerve block versus epidural analgesia for unilateral total knee arthroplasty. | Pain control following total knee arthroplasty (TKA) is crucial to hasten rehabilitation and decrease morbidity. We evaluated whether there is a difference between epidural infusion and continuous femoral nerve block with respect to postoperative pain control and rehabilitation course. Fifty patients completed the stud... | 25,149,364 | [
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pENCODE: a plant encyclopedia of DNA elements. | ENCODE projects exist for many eukaryotes, including humans, but as of yet no defined project exists for plants. A plant ENCODE would be invaluable to the research community and could be more readily produced than its metazoan equivalents by capitalizing on the preexisting infrastructure provided from similar projects.... | 25,149,370 | [
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Effect of DC-CIK cell on the proliferation, apoptosis and differentiation of leukemia cells. | To observe the effect of co-culture cytokine-induced killer cells (CIK) and homologous dendritic cells (DC) on the proliferative activity and phenotype change of the DC-CIK cell and the cell killing activity of leukemia HL-60. 50 mL cord blood sample was obtained from infants delivered by full term healthy woman and th... | 25,149,382 | [
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0.005540632,
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0.2930339,
0.4890703,
0.3848185,
0.0006430283,
0... |
Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment. | Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis, which affects small- and medium-sized blood vessels and is often associated with cytoplasmic ANCA. GPA occurs in patients between 45 and 60 years old of both genders, and is rarely observed in blacks. The prevalence of GPA increases along a so... | 25,149,391 | [
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0.1406562,
0.2637915,
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Vegetarian diet, Seventh Day Adventists and risk of cardiovascular mortality: a systematic review and meta-analysis. | Dietary interventions are an important component of cardiovascular risk factor management although their impact on cardiovascular risk and mortality remains uncertain. We have studied influence of a vegetarian diet on cardiovascular risk and mortality. We searched MEDLINE and EMBASE for comparative studies that evaluat... | 25,149,402 | [
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0.0793957,
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0.2944825,
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0.322535,
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0... |
Aging with HIV: a model of disability. | The purpose of this qualitative study was to develop a theoretical model describing the disability experienced by older adults living with HIV. Forty nine HIV positive men and women over the age of 50 years participated in in-depth qualitative interviews. Transcribed interviews were analyzed using grounded theory techn... | 25,149,413 | [
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0.4585494,
0.1425606,
0.... |
Climate change and the emergence of vector-borne diseases in Europe: case study of dengue fever. | Dengue fever is the most prevalent mosquito-borne viral disease worldwide. Dengue transmission is critically dependent on climatic factors and there is much concern as to whether climate change would spread the disease to areas currently unaffected. The occurrence of autochthonous infections in Croatia and France in 20... | 25,149,418 | [
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0.1182155,
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0.1076679,
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... |
Fusion imaging using subtracted and unsubtracted rotational angiography for pretherapeutic evaluation of dural arteriovenous fistulas. | We describe the clinical utility of an imaging technique that combines 3D subtracted and unsubtracted rotational angiography for evaluation of the angioarchitecture of dural arteriovenous fistulas (DAVFs). From May 2010 to June 2013, 21 consecutive patients with intracranial DAVFs (22 lesions) underwent 3D angiography ... | 25,149,420 | [
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0.2770233,
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0.07460278,
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Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities. | The International Psoriasis Council, a global nonprofit organization dedicated to advancing psoriasis research and treatment, led an initiative to better define the association of various cardiometabolic comorbidities with psoriasis. In November 2013, a workshop was held in Boston, Mass. By assembling a panel of global... | 25,149,424 | [
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0.00507027,
0.2230711,
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0.395663,
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... |
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