title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Generalized models for rock joint surface shapes. | Generalized models of joint surface shapes are the foundation for mechanism studies on the mechanical effects of rock joint surface shapes. Based on extensive field investigations of rock joint surface shapes, generalized models for three level shapes named macroscopic outline, surface undulating shape, and microcosmic... | 25,152,901 | [
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Analytical approximate solutions for a general class of nonlinear delay differential equations. | We use the polynomial least squares method (PLSM), which allows us to compute analytical approximate polynomial solutions for a very general class of strongly nonlinear delay differential equations. The method is tested by computing approximate solutions for several applications including the pantograph equations and a... | 25,152,920 | [
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AVQS: attack route-based vulnerability quantification scheme for smart grid. | A smart grid is a large, consolidated electrical grid system that includes heterogeneous networks and systems. Based on the data, a smart grid system has a potential security threat in its network connectivity. To solve this problem, we develop and apply a novel scheme to measure the vulnerability in a smart grid domai... | 25,152,923 | [
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Beamforming transmission in IEEE 802.11ac under time-varying channels. | The IEEE 802.11ac wireless local area network (WLAN) standard has adopted beamforming (BF) schemes to improve spectral efficiency and throughput with multiple antennas. To design the transmit beam, a channel sounding process to feedback channel state information (CSI) is required. Due to sounding overhead, throughput i... | 25,152,927 | [
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Long term effects of tear gases on respiratory system: analysis of 93 cases. | This study aimed to assess the long-term respiratory effects of tear gases among the subjects with history of frequent exposure. A questionnaire by NIOSH and pulmonary function tests was performed in 93 males exposed to the tear gases frequently and 55 nonexposed subjects. The mean numbers of total exposure and last 2 ... | 25,152,930 | [
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Partial least-squares-discriminant analysis differentiating Chinese wolfberries by UPLC-MS and flow injection mass spectrometric (FIMS) fingerprints. | Lycium barbarum L. fruits (Chinese wolfberries) were differentiated for their cultivation locations and the cultivars by ultraperformance liquid chromatography coupled with mass spectrometry (UPLC-MS) and flow injection mass spectrometric (FIMS) fingerprinting techniques combined with chemometrics analyses. The partial... | 25,152,955 | [
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Probiotics and synbiotics may improve liver aminotransferases levels in non-alcoholic fatty liver disease patients. | Non-alcoholic fatty liver disease (NAFLD) is defined as a spectrum of liver diseases ranging from simple steatosis to steatohepatitis (NASH). Alterations in intestinal microbiota and inflammatory response may play a key role in disease progression and development of complications in liver diseases, mainly in cirrhosis ... | 25,152,979 | [
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Protease inhibitor-based triple therapy is highly effective for hepatitis C recurrence after liver transplant: a multicenter experience. | Hepatitis C (HCV) continues to be the leading indication for liver transplantation (LT). Sustained virological response (SVR) rates to pegylated interferon (PEG-IFN) and ribavirin (RBV) therapy for recurrent HCV in Genotype 1 (G1) LT recipients have been disappointing (30-40%). Experience with triple therapy using prot... | 25,152,985 | [
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Hepatitis E virus exposure in pregnant women in rural Durango, Mexico. | Hepatitis E virus (HEV) infection represents a risk for mortality in pregnant women. The seroepidemiology of HEV infection in rural pregnant women in the Americas is largely unknown. The aim of the study was to determine the seroepidemiology of anti-HEV IgG antibodies in rural pregnant women in Durango, Mexico. The pre... | 25,152,983 | [
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Ultra-sensitive procalcitonin may help rule out bacterial infections in patients with cirrhosis. | Bacterial infections are frequent complications in patients with cirrhosis. Since they are associated with poor outcomes, antibiotics are frequently over-prescribed. Surrogate markers of bacterial infections, like procalcitonin, are needed to better discriminate between infected and not infected patients. To evaluated ... | 25,152,987 | [
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20(S)-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng. | The root of Panax ginseng C. A. Meyer (Araliaceae) is a well-known herbal medicine in East Asia. The major bioactive metabolites in this root are commonly identified as ginsenosides. A series of ginsenosides were determined for in vitro human recombinant aldose reductase. This Letter aims to clarify the structural requ... | 25,152,999 | [
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Cathinone, an active principle of Catha edulis, accelerates oxidative stress in the limbic area of swiss albino mice. | Cathinone hydrochloride is an active principle of the khat plant (Catha edulis) that produces pleasurable and stimulating effects in khat chewers. To the best of our knowledge no data of cathinone on oxidative stress in limbic areas of mice is available. This is the first study of cathinone on oxidative stress in limbi... | 25,153,022 | [
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Immunohistological characterization of intercellular junction proteins in rhesus macaque intestine. | Epithelial junctions play an important role in regulating paracellular permeability and intercellular adhesion. It has been reported that changes in the density of epithelial junctions and/or distribution pattern can contribute to various gastrointestinal (GI) disorders. In this study, we investigated the distribution ... | 25,153,024 | [
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A novel gross indel in the growth hormone releasing hormone receptor gene of Indian IGHD patients. | Cohort specific mutations in the growth hormone (GH1) and growth hormone-releasing hormone receptor (GHRHR) genes have been reported worldwide in isolated growth hormone deficiency (IGHD) patients. However, limited data is available on ethnically diverse Indian IGHD patients. The aim of the study was to find GH1 and GH... | 25,153,028 | [
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Evaluation of the CHUMS Child Bereavement Group: A Pilot Study Examining Statistical and Clinical Change. | This article describes the largest evaluation of a UK child bereavement service to date. Change was assessed using conventional statistical tests as well as clinical significance methodology. Consistent with the fact that the intervention was offered on a universal, preventative basis, bereaved young people experienced... | 25,153,045 | [
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Intentional injuries in young Ohio children: is there urban/rural variation? | Intentional injuries are the third leading cause of death in children 1 year to 4 years of age. The epidemiology of these injuries based on urban/rural geography and economic variables has not been clearly established. The study purposes are (1) to determine the rate of severe intentional injuries in children younger t... | 25,153,053 | [
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Giant palatal schwannoma. | Schwannoma is a benign tumor that arises from nerves that contain Schwann cells. We report a case of giant schwannoma of the hard palate, which originated from the greater palatine nerve and is interesting for its large dimensions. | 25,153,061 | [
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Quick and accurate measures in negative pressure pulmonary edema: a guideline for orthognathic surgeons. | Perioperative pulmonary edema is a rare complication of maxillofacial surgery. However, this potentially fatal complication may arise during any maxillofacial surgery. Negative pressure pulmonary edema can be caused by upper airway obstruction after operation. When this phenomenon arises, if not treated properly, it pr... | 25,153,065 | [
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Integration of apo-α-phycocyanin into phycobilisomes and its association with FNRL in the absence of the phycocyanin α-subunit lyase (CpcF) in Synechocystis sp. PCC 6803. | Phycocyanin is an important component of the phycobilisome, which is the principal light-harvesting complex in cyanobacteria. The covalent attachment of the phycocyanobilin chromophore to phycocyanin is catalyzed by the enzyme phycocyanin lyase. The photosynthetic properties and phycobilisome assembly state were charac... | 25,153,076 | [
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Genome-wide association mapping for seedling and adult plant resistance to stripe rust in synthetic hexaploid wheat. | Use of genetic diversity from related wild and domesticated species has made a significant contribution to improving wheat productivity. Synthetic hexaploid wheats (SHWs) exhibit natural genetic variation for resistance and/or tolerance to biotic and abiotic stresses. Stripe rust caused by (Puccinia striiformis f. sp. ... | 25,153,126 | [
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Chronotype and time-of-day effects on mood during school day. | Existing evidence suggests an association between mood, time-of-day and morningness-eveningness (M-E). Since few studies have been carried out among adolescents, in this study daily mood fluctuations were analyzed in the naturalistic school context during 2 d in order to test how chronotype and time-of-day are related ... | 25,153,134 | [
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Analytical model of large data transactions in CoAP networks. | We propose a novel analytical model to study fragmentation methods in wireless sensor networks adopting the Constrained Application Protocol (CoAP) and the IEEE 802.15.4 standard for medium access control (MAC). The blockwise transfer technique proposed in CoAP and the 6LoWPAN fragmentation are included in the analysis... | 25,153,143 | [
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Organ-based tube current modulation: are women's breasts positioned in the reduced-dose zone? | To retrospectively determine the potential of organ-based tube current modulation ( OBTCM organ-based tube current modulation ) to reduce the radiation dose delivered to breast tissue by computed tomography (CT) by determining breast angular position in relation to the zones of decreased versus increased radiation. The... | 25,153,159 | [
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High temperature stability of onion-like carbon vs highly oriented pyrolytic graphite. | The thermodynamic stability of onion-like carbon (OLC) nanostructures with respect to highly oriented pyrolytic graphite (HOPG) was determined in the interval 765-1030 K by the electromotive force (emf) measurements of solid electrolyte galvanic cell: (Low) Pt|Cr3C2,CrF2,OLC|CaF2s.c.|Cr3C2,CrF2,HOPG|Pt (High). The free... | 25,153,181 | [
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Improving access to health care for undocumented immigrants in the United States. | To identify policies that increase access to health care for undocumented Mexican immigrants. Four focus groups (n=34 participants) were conducted with uninsured Mexican immigrants in Los Angeles, California. The feasibility and desirability of different policy proposals for increasing access were discussed by each gro... | 25,153,191 | [
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Layer-dependent optical conductivity in atomic thin WS₂ by reflection contrast spectroscopy. | Optical conductivity, which originates from the interband transition due to electron-phonon interaction, is one of the powerful tools used for studying the electronic states in layered transition metal dichalcogenides (TMDCs). Here, we report for the first time the optical conductivity of WS2, one of the emerging class... | 25,153,193 | [
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The contribution of antibiotic resistance mechanisms in clinical Burkholderia cepacia complex isolates: an emphasis on efflux pump activity. | Due to the limited information of the contribution of various antibiotic resistance mechanisms in clinical Burkholderia cepacia complex isolates, Antibiotic resistance mechanisms, including integron analysis, identification of quinolone resistance-determining region mutations, measurement of efflux pump activity, and s... | 25,153,194 | [
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Biomechanical investigations of the secondary stability of commercial short dental implants in porcine ribs. | The use of short implants has increased widely within the last years. However, the stability of these implants has not yet been comprehensively investigated, in particular the difference in geometry and dimension of short implants. The aim of the present study was to investigate experimentally the difference of the sec... | 25,153,205 | [
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Is there a stepwise increase in neonatal morbidities according to histological stage (or grade) of acute chorioamnionitis and funisitis?: effect of gestational age at delivery. | To test if there is a stepwise difference in neonatal outcomes according to the stage (or grade) of histological inflammatory response in the chorioamniotic membranes and umbilical cords of preterm premature rupture of membranes (PPROM). This retrospective study included singleton pregnancies diagnosed as PPROM and del... | 25,153,209 | [
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Immunological cross-reactivity and neutralisation of European viper venoms with the monospecific Vipera berus antivenom ViperaTAb. | Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom. Here we investigate the capability of the monospecific V. berus antivenom, ViperaTAb®, to cross-react with, and ne... | 25,153,254 | [
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Case 209: Disseminated coccidioidal spondylodiskitis. | History A 46-year-old Hispanic man with a medical history of diabetes and hepatitis C and an unclear history of prior infectious disease presented to the emergency department of a community medical center in the northeastern United States with a 3-month history of back pain. The patient was originally from Mexico and h... | 25,153,278 | [
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Gold weight implants for management of thyroid-related upper eyelid retraction. | To evaluate the use of gold weight implantation in the upper eyelid in the treatment of upper eyelid retraction caused by thyroid ophthalmopathy as regards the cosmetic and functional results and the safety of the procedure. This is a surgical intervention case series study. The study was carried out in Ophthalmology D... | 25,153,311 | [
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Mechanistic studies of a novel mycophenolic acid-glucosamine conjugate that attenuates renal ischemia/reperfusion injury in rat. | Renal ischemia/reperfusion (I/R) injury causes high mortality and morbidity during renal procedures, yet current drugs should be used at high doses or for long periods due to lack of tissue specificity. In previous work we described a novel mycophenolic acid-glucosamine conjugate (MGC) that targets the proximal tubule ... | 25,153,320 | [
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Alcohol tax policy and related mortality. An age-period-cohort analysis of a rapidly developed Chinese population, 1981-2010. | To delineate the temporal dynamics between alcohol tax policy changes and related health outcomes, this study examined the age, period and cohort effects on alcohol-related mortality in relation to changes in government alcohol policies. We used the age-period-cohort modeling to analyze retrospective mortality data ove... | 25,153,324 | [
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Highly selective palladium-catalyzed cross-coupling of secondary alkylzinc reagents with heteroaryl halides. | The highly selective palladium-catalyzed Negishi coupling of secondary alkylzinc reagents with heteroaryl halides is described. The development of a series of biarylphosphine ligands has led to the identification of an improved catalyst for the coupling of electron-deficient heterocyclic substrates. Preparation and cha... | 25,153,332 | [
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Immunogenetics of small ruminant lentiviral infections. | The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similar... | 25,153,344 | [
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AAV-sBTLA facilitates HSP70 vaccine-triggered prophylactic antitumor immunity against a murine melanoma pulmonary metastasis model in vivo. | Activation of the BTLA-HVEM co-inhibitory signaling pathway impairs antitumor immunity. Our previous study demonstrated that the extracellular domain of murine BTLA (the soluble form of BTLA) can facilitate HSP70 vaccine-triggered antitumor immunity by blocking BTLA-HVEM interactions in a murine TC-1 non-metastatic tum... | 25,153,350 | [
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Implications of stemness-related signaling pathways in breast cancer response to therapy. | There is accumulating evidence that breast cancer may arise from a small subpopulation of transformed mammary stem/progenitor cells, termed breast cancer-initiating cells (BCICs), responsible for initiation and maintenance of cancer. BCICs have been identified in clinical specimens based on CD44(+)/CD24(-/low) membrane... | 25,153,354 | [
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The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition. | Cripto-1 (CR-1)/Teratocarcinoma-derived growth factor1 (TDGF-1) is a cell surface glycosylphosphatidylinositol (GPI)-linked glycoprotein that can function either in cis (autocrine) or in trans (paracrine). The cell membrane cis form is found in lipid rafts and endosomes while the trans acting form lacking the GPI ancho... | 25,153,355 | [
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Role for monoaminergic systems in the antidepressant and anxiolytic properties of the hydroethanolic leaf extract from Adenia cissampeloides. | Adenia cissampeloides (Planch ex. Hook) Harms (Passifloraceae) leaf infusion is used in traditional African medicine as a stimulant to treat depression and insanity. Thus, this study investigates antidepressant and anxiolytic activities of the hydroethanol leaf extract of Adenia cissampeloides (ACE) in mice. ACE (50-20... | 25,153,375 | [
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CrataBL, a lectin and Factor Xa inhibitor, plays a role in blood coagulation and impairs thrombus formation. | Arterial thrombosis is an important complication of diabetes and cancer, being an important target for therapeutic intervention. Crataeva tapia bark lectin (CrataBL) has been previously shown to have hypoglycemiant effect and also to induce cancer cell apoptosis. It also showed inhibitory activity against Factor Xa (Ki... | 25,153,385 | [
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Estimation of age- and comorbidities-adjusted percentiles of high-sensitivity cardiac troponin T levels in the elderly. | Cardiac troponin level measured by high-sensitivity assays (hs-cTn) in the elderly is frequently found higher than the 99th percentile upper reference limit, making the diagnosis of acute coronary syndromes (ACS) difficult. This study aimed at: 1) identifying determinants of hs-cTnT levels in an unselected population o... | 25,153,394 | [
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Triple positive antiphospholipid antibody profile in outpatients with tests for lupus anticoagulants. | A triple positive antiphospholipid (aPL) antibody profile [two positive serum IgG aPL antibodies along with one positive functional plasma lupus anticoagulant (LAC) test result] is associated with an increased risk for thrombosis, whereas patients with single positive test results may have little to no increased risk. ... | 25,153,406 | [
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Determination of quality control limits for serological infectious disease testing using historical data. | An effective quality control (QC) program requires the establishment of control limits within which the results of the QC sample is expected to fall. Traditionally, the mean plus/minus two standard deviations calculated for a set of QC sample results is used to establish control limits. Allowable total error (TEa) and ... | 25,153,420 | [
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SNPs in the adiponectin receptor 2 gene and their associations with chicken performance traits. | The adiponectin receptor 2 (ADIPOR2) is a receptor for both globular and full-length adiponectin. In the current study, two genetic variations in ADIPOR2 gene were identified in an F2 resource population of Gushi chicken and Anka broiler. Association analysis between the two SNPs and chicken performance traits were det... | 25,153,449 | [
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Prokaryotic expression of ovis aries conglutinin encoding neck and carbohydrate recognition domain and its functional characterization. | Conglutinin, a soluble pattern recognition receptor of innate immune system in bovines is known for its potential defensive activity against microorganisms either by direct agglutination in the presence of calcium or by acting as opsonin. In the present study, sheep (Ovis aries) conglutinin encoding neck and carbohydra... | 25,153,452 | [
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The Los Angeles County Community Disaster Resilience Project - a community-level, public health initiative to build community disaster resilience. | Public health officials need evidence-based methods for improving community disaster resilience and strategies for measuring results. This methods paper describes how one public health department is addressing this problem. This paper provides a detailed description of the theoretical rationale, intervention design and... | 25,153,472 | [
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Artificial intelligence in public health prevention of legionelosis in drinking water systems. | Good quality water supplies and safe sanitation in urban areas are a big challenge for governments throughout the world. Providing adequate water quality is a basic requirement for our lives. The colony forming units of the bacterium Legionella pneumophila in potable water represent a big problem which cannot be overlo... | 25,153,475 | [
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Population structure of mountain pine beetle symbiont Leptographium longiclavatum and the implication on the multipartite beetle-fungi relationships. | Over 18 million ha of forests have been destroyed in the past decade in Canada by the mountain pine beetle (MPB) and its fungal symbionts. Understanding their population dynamics is critical to improving modeling of beetle epidemics and providing potential clues to predict population expansion. Leptographium longiclava... | 25,153,489 | [
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Menin immunoreactivity in secretory granules of human pancreatic islet cells. | The protein product of the Multiple Endocrine Neoplasia Type I (MEN1) gene is thought to be involved in predominantly nuclear functions; however, immunohistochemical (IHC) analysis data on cellular localization are conflicting. To further investigate menin expression, we analyzed human pancreas (an MEN1 target organ) u... | 25,153,502 | [
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Paraoxonase 1 status and interactions between Q192R functional genotypes by smoking contribute significantly to total plasma radical trapping antioxidant potential. | The measurement of the total radical trapping antioxidant potential (TRAP) is a general marker of peripheral blood antioxidant defenses. Paraoxonase 1 (PON1) is a potent antioxidant, which protects against lipid peroxidation. The study aimed to examine the relation between TRAP levels and PON1 activity, PON1 Q192R func... | 25,153,516 | [
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Pituitary abscess in an adolescent girl: a case report and review of the literature. | We report the case of a 15-year-old girl who presented with a history of recurrent bitemporal headaches for the last 2 months. In the prior few days, she complained of neck pain, emesis, phonophobia and photophobia, but no fever. Additional symptoms included polydipsia, polyuria and weight gain in the last year. Magnet... | 25,153,562 | [
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Growth failure associated with early neglect: pilot comparison of neglected US children and international adoptees. | The long-lasting impact of different neglectful environments on growth in children is not well studied. Three groups of children, 3-10 years old, were recruited (n=60): previously institutionalized international adoptees living in stable home environments for at least 2 years (IA; n=15), children with a history of negl... | 25,153,568 | [
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Effect of l-thyroxine supplementation on infants with transient hypothyroxinemia of prematurity at 18 months of corrected age: randomized clinical trial. | Our objective was to evaluate effects of levothyroxine (l-T4) supplementation against neurodevelopmental outcomes at 18 months of corrected age in very-low-birth-weight (VLBW) infants with hypothyroxinemia but without elevated thyroid-stimulating hormone (TSH) concentration. VLBW infants who had plasma TSH concentratio... | 25,153,575 | [
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Influence of cross-link structure, density and mechanical properties in the mesoscale deformation mechanisms of collagen fibrils. | Collagen is a ubiquitous protein with remarkable mechanical properties. It is highly elastic, shows large fracture strength and enables substantial energy dissipation during deformation. Most of the connective tissue in humans consists of collagen fibrils composed of a staggered array of tropocollagen molecules, which ... | 25,153,614 | [
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... |
Enterococcal endocarditis complicated with ruptured infected-intracranial aneurysm: with pharmacokinetic-pharmacodynamic documentation in proof of the successful antimicrobial treatment. | A 74-year-old man presented with sudden onset of aphasia and apraxia. Magnetic resonance image (MRI) of the brain disclosed a left frontal hemorrhage. The concomitant low grade fever suggestive of infection was unresponsive to cefazolin 1 g q12h, and refractory to piperacillin (PIPC) 2 g q8h. Blood culture grew enteroc... | 25,153,621 | [
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Enhancement of chlorogenic acid production in hairy roots of Platycodon grandiflorum by over-expression of an Arabidopsis thaliana transcription factor AtPAP1. | To improve the production of chlorogenic acid (CGA) in hairy roots of Platycodon grandiflorum, we induced over-expression of Arabidopsis thaliana transcription factor production of anthocyanin pigment (AtPAP1) using an Agrobacterium rhizogenes-mediated transformation system. Twelve hairy root lines showing over-express... | 25,153,629 | [
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Epiretinal membrane peeling after uncomplicated primary retinal detachment repair. | To identify rates and potential risk factors for epiretinal membrane (ERM) and for membrane peel (MP) after 23- or 25-gauge repair and to compare outcomes for eyes with ERM that underwent MP versus observation. Review of 587 eyes with ERM after retinal detachment repair. Patients who developed ERM either underwent pars... | 25,153,659 | [
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Enhanced depth imaging spectral-domain optical coherence tomography findings in choroidal neurofibromatosis. | The authors report multimodal imaging findings, including enhanced depth imaging-optical coherence tomography, in an affected child with choroidal neurofibromatosis. Novel features such as choroidal vessel compression from choroidal nodules related to neurofibromatosis type 1 and an increased subfoveal choroidal thickn... | 25,153,660 | [
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Phosducin regulates secretory activity in TT line of thyroid parafollicular C cells. | The endocrine activity of the thyroid gland is accomplished by its follicular and parafollicular cells. In these cells, numerous G proteins-dependent pathways are active and potentially could be regulated by a 33-kDa cytoplasmic protein phosducin, which interacts with the Gβ subunit and may compete with Gα or Gβγ dimer... | 25,153,685 | [
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Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells. | Most anticancer drugs are not able to cross the blood-brain barrier (BBB) effectively while surgery and radiation therapy cannot eradicate brain glioma cells and glioma stem cells (GSCs), hence resulting in poor prognosis with high recurrence rates. In the present study, a kind of multifunctional targeting daunorubicin... | 25,153,726 | [
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Exercise intervention to reduce depressive symptoms in adults with intellectual disabilities. | People with intellectual disabilities are often reported as having depressive symptoms. Although the antidepressant effect of exercise has been systematically recognized, research concerning the role of exercise on depressive symptoms in people with intellectual disabilities is still scant. A 12-wk. exercise interventi... | 25,153,733 | [
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Examining the relationship between sex and motivation in triathletes. | The present paper assesses the relationship between sex and motivation in triathletes utilising a multidimensional measurement of motivation in sports. Data were collected from 138 triathlon participants (age range 17-72 years): 95 men (M = 36.7 yr., SD = 10.7) and 43 women (M = 34.6 yr., SD = 9.9). Measures included t... | 25,153,737 | [
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Study of reaction time to visual stimuli in athletes with and without a hearing impairment. | This study analyzes the differences in manual reaction time (RT) to visual stimuli in two samples of physically active persons: a group of athletes without hearing impairment (n = 79; M age = 22.6 yr., SD = 3.7) and a group of athletes with hearing impairment (n = 44, M age = 25.6 yr., SD = 5.0). Reaction time (RT) was... | 25,153,743 | [
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Visuomotor control in continuous response time tasks across different age groups. | The goal was to examine whether visuomotor control and choice response time shared age-related developmental trajectories, and if prior computer experience played an important role in control processes. Children (6-7, 8-9, 10-11 yr.), younger adults (24 yr.) and older adults (76 yr.) performed the cursor pointing and c... | 25,153,747 | [
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Three-component coupling based on flash chemistry. Carbolithiation of benzyne with functionalized aryllithiums followed by reactions with electrophiles. | A flow microreactor method for three-component coupling of benzyne was developed based on flash chemistry. o-Bromophenyllithium generated from 1-bromo-2-iodobenzene and a functionalized aryllithium generated from the corresponding aryl halide were mixed at -70 °C. In the subsequent reactor o-bromophenyllithium is decom... | 25,153,763 | [
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The association between metformin use and oncologic outcomes among surgically treated diabetic patients with localized renal cell carcinoma. | Metformin inhibits renal cell carcinoma (RCC) cell proliferation both in vitro and in vivo; however, clinical data regarding the effect of metformin in patients with RCC are lacking. We evaluated the association of metformin use with outcomes among patients with surgically treated localized RCC. We identified 283 conse... | 25,153,774 | [
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Revealing the functional states in the active site of BLUF photoreceptors from electrochromic shift calculations. | Photoexcitation with blue light of the flavin chromophore in BLUF photoreceptors induces a switch into a metastable signaling state that is characterized by a red-shifted absorption maximum. The red shift is due to a rearrangement in the hydrogen bond pattern around Gln63 located in the immediate proximity of the isoal... | 25,153,778 | [
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Transcranial oscillatory direct current stimulation during sleep improves declarative memory consolidation in children with attention-deficit/hyperactivity disorder to a level comparable to healthy controls. | Slow oscillations (<1 Hz) during slow wave sleep (SWS) promote the consolidation of declarative memory. Children with attention-deficit/hyperactivity disorder (ADHD) have been shown to display deficits in sleep-dependent consolidation of declarative memory supposedly due to dysfunctional slow brain rhythms during SW... | 25,153,776 | [
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[Treatment of pulmonary arterial hypertension]. | Patients with pulmonary arterial hypertension (PAH) must be referred to expert centers (reference center and competences centers in the French PAH network). Despite progresses in the knowledge of PAH pathophysiology, it is still a devastating disease needing an aggressive approach of therapy to improve long-term outcom... | 25,153,783 | [
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Catalytic enantioselective protoboration of disubstituted allenes. Access to alkenylboron compounds in high enantiomeric purity. | Proto-boryl additions to 1,1-disubstituted allenes in the presence of 1.0-5.0 mol % of chiral NHC-Cu complexes, B2(pin)2, and t-BuOH proceed to afford alkenyl-B(pin) products in up to 98% yield, >98:2 site selectivity, and 98:2 er. The enantiomerically enriched alkenylboron products can be converted to otherwise dif... | 25,153,792 | [
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Glenoid fracture after arthroscopic Bankart repair: case series and biomechanical analysis. | To examine whether anchors used in arthroscopic Bankart repair increased the risk of subsequent fracture, six intact polyurethane scapulae and six with three 3.0-mm suture anchors placed along the anteroinferior glenoid were compared. An axial load of 1 mm/s was applied to the anteroinferior glenohumeral joint with a p... | 25,153,814 | [
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High-performance supercapacitor electrode based on the unique ZnO@Co₃O4₄ core/shell heterostructures on nickel foam. | Currently, tremendous attention has been paid to the rational design and synthesis of unique core/shell heterostructures for high-performance supercapacitors. In this work, the unique ZnO@Co3O4 core/shell heterostructures on nickel foam are successfully synthesized through a facile and cost-effective hydrothermal metho... | 25,153,820 | [
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miRNAs in tumor radiation response: bystanders or participants? | There is increasing interest in defining a functional association between miRNAs and tumor radiation response, with the double aim of rationally designing miRNA-based strategies to increase patient radiosensitivity and identifying novel biomarkers of treatment response. Although it has been demonstrated that several mi... | 25,153,824 | [
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Synthesis of phenanthrenes through copper-catalyzed cross-coupling of N-tosylhydrazones with terminal alkynes. | A novel protocol for the synthesis of phenanthrenes through the copper-catalyzed reaction of aromatic tosylhydrazones with terminal alkynes is explored. The reaction proceeds via the formation of an allene intermediate and subsequent six-π-electron cyclization-isomerization, affording phenanthrene derivatives in good y... | 25,153,826 | [
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Physical disability, anxiety and depression in people with MS: an internet-based survey via the UK MS Register. | People with Multiple Sclerosis are known to have a relatively high prevalence of both anxiety and depression. Studies of the relationship between physical disability and mental health in people with MS have reported mixed results, showing the need for further work. Between May 2011 and April 2012, 4516 people completed... | 25,153,835 | [
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A study of intelligence in Jordan . | The Raven's Standard Progressive Matrices test was standardized in Jordan in 2004 on a sample of 1,015 school students ages 12 to 17 yr. The sample obtained a British IQ of 82.6. | 25,153,849 | [
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Addressing the configuration stability of lithiated secondary benzylic carbamates for the development of a noncryogenic stereospecific boronate rearrangement. | A practical noncryogenic process for the Aggarwal stereospecific boronate rearrangement with chiral secondary benzylic carbamates has been developed. The use of LDA instead of sec-BuLi combined with an in situ trapping of the unstable lithiated carbamate was critical to success. Furthermore, this new process increased ... | 25,153,850 | [
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Partial characterization of an enzymatic extract from Bentong ginger (Zingiber officinale var. Bentong). | Extraction of protease from a local ginger rhizome (Zingiber officinale var. Bentong) was carried out. The effect of extraction pH (6.4, 6.8, 7.0, 7.2, 7.6, 8.0, 8.4, and 8.8) and stabilizers (0.2% ascorbic acid, 0.2% ascorbic acid and 5 mM EDTA, or 10 mM cysteine and 5 mM EDTA) on protease activity during extraction w... | 25,153,861 | [
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... |
Ultrasound-assisted extraction of antioxidants in Misai Kucing (Orthosiphon stamineus). | Ultrasound-assisted extraction (UAE) with ethanol was used to extract the compounds responsible for the antioxidant activities of Misai Kucing (Orthosiphon stamineus). Response surface methodology (RSM) was used to optimize four independent variables: ethanol concentration (%), amplitude (%), duty cycle (W/s) and extra... | 25,153,876 | [
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Anti-inflammatory effect of Momordica charantia in sepsis mice. | Wild bitter gourd (Momordica charantia L. var. abbreviate Seringe), a common vegetable in Asia, is used in traditional medicine to treat various diseases, including inflammation. Extant literature indicates that wild bitter gourds have components that activate PPARα and PPARγ. This research probed the influence of addi... | 25,153,878 | [
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... |
Impact of ionic liquids in aqueous solution on bacterial plasma membranes studied with molecular dynamics simulations. | The impact of five different imidazolium-based ionic liquids (ILs) diluted in water on the properties of a bacterial plasma membrane is investigated using molecular dynamics (MD) simulations. Cations considered are 1-octyl-3-methylimidazolium (OMIM), 1-octyloxymethyl-3-methylimidazolium (OXMIM), and 1-tetradecyl-3-meth... | 25,153,890 | [
-0.2774248,
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0.02191633,
-0.02283991,
-0.1879447,
-0.01333602,
0.1799873,
0.009027018,
0.08961697,
-0.5858556,
0.1767548,
-0.4636912,
0.01607426,
-0.08406021,
0.001984955,
0.156678,
0.3996058,
-0.05... |
In vitro progression of artificial white spot lesions sealed with an infiltrant resin. | This study assessed the ability of an infiltrant resin (Icon, DMG Chemisch-Pharmazeutische Fabrik GmbH, Hamburg, Germany) to prevent artificial lesion progression in vitro when used to impregnate white spot lesions and also assessed the effect of saliva contamination on resin infiltration. Enamel specimens (n=252) were... | 25,153,897 | [
-0.1363283,
0.3668245,
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Perceived Resources and Environmental Correlates of Domain-Specific Physical Activity in Rural Midwestern Adults. | Rural adults participate in lower levels of physical activity (PA) than urban or suburban adults. Due to known effects of the environment on PA participation, this study examined perceived ecological correlates (social, environmental, and policy) of domain- and intensity-specific PA in rural adults. A cross-sectional s... | 25,153,923 | [
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0.02089025,
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0.271865,
0.00990689... |
Distally Based Saphenous Nerve-Greater Saphenous Venofasciocutaneous Flap for Reconstruction of Soft Tissue Defects in Distal Lower Leg. | To this day, the reconstruction of soft tissue defects in the distal lower leg is still a challenge for reconstructive surgeons. At present, free flap, musculocutaneous flap, anterior and posterior tibial artery flap, cross-leg flap, and distally based neurocutaneous flap are the main surgical alternatives. However, th... | 25,153,925 | [
-0.2127898,
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0.09075467,
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0.1070512,
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0.08901433,
-0.0409... |
Music and psychophysiological recovery from stress. | This experimental study examined whether listening to self-chosen music after stress exposure improves mood, decreases subjective arousal and rumination, and facilitates cardiovascular recovery. Participants (N = 123) were exposed to a mental arithmetic task with harassment to induce stress. Afterward, participants wer... | 25,153,936 | [
-0.2734707,
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0.09276227,
0.05280976,
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0.1742938,
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Effect of sodium arsenite on reproductive organs of female Wistar rats. | The present study was performed to investigate the subchronic effect of sodium arsenite on female Wistar rats. Mature female rats were divided into 4 groups of 12 animals each. Group I received distilled water, whereas the other 3 groups received sodium arsenite at 10, 30, and 50 µg/L doses for 60 days through drinking... | 25,153,939 | [
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0.2252,
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0.01883056,
0.386438,
-0.0063644... |
Factor analysis of the Foreign Language Classroom Anxiety Scale in Korean learners of English as a foreign language. | This study examined the latent constructs of the Foreign Language Classroom Anxiety Scale (FLCAS) using two different groups of Korean English as a foreign language (EFL) university students. Maximum likelihood exploratory factor analysis with direct oblimin rotation was performed among the first group of 217 participa... | 25,153,961 | [
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0.03660928,
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Independent and interdependent self-construals do not predict analytic or holistic reasoning. | Independent self-construals in Western cultures may promote analytic information processing and low field dependence, while interdependent self-construals in Eastern cultures may foster holistic information processing and high field dependence. To examine these ideas, the social orientation and cognitive style of 254 i... | 25,153,966 | [
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0.01009829,
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0.05158595,
0.346... |
Accuracy of Canadian food labels for sodium content of food. | The accuracy of the Nutrition Facts table (NFt) has a significant impact on Canadian efforts to reduce dietary sodium and monitor sodium content in foods. This study assessed the accuracy of sodium (and calories, trans fat, saturated fat, sugar) reported on the NFt for selected foods and beverages in Canada. The Canadi... | 25,153,971 | [
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0.1758462,
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0.09536183,
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0.3105043,
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... |
[Cultural components within DSM-5: achievements, hopes, and expectations]. | Cultural Psychiatry deals with the description, definition, evaluation and management of psychiatric conditions as a clinical reflection of cultural factors within an integral context, and as an explanatory, interpretative, nosological, therapeutic and preventive attribute in professional practice. This article attempt... | 25,153,977 | [
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0.1878939,
0.04972383,
0.01394132,
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Psychometric investigation of the abbreviated concussion symptom inventory in a sample of U.S. Marines returning from combat. | This study describes the psychometric investigation of an 11-item symptom checklist, the Abbreviated Concussion Symptom Inventory (ACSI). The ACSI is a dichotomously scored list of postconcussive symptoms associated with mild traumatic brain injury. The ACSI was administered to Marines (N = 1,435) within the 1st month ... | 25,153,983 | [
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Helicene quinones: redox-triggered chiroptical switching and chiral recognition of the semiquinone radical anion lithium salt by electron nuclear double resonance spectroscopy. | We present the synthesis and characterization of enantiomerically pure [6]helicene o-quinones (P)-(+)-1 and (M)-(-)-1 and their application to chiroptical switching and chiral recognition. (P)-(+)-1 and (M)-(-)-1 each show a reversible one-electron reduction process in their cyclic voltammogram, which leads to the form... | 25,154,039 | [
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0.3938082,
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0.2219055,
0.04502382... |
Inter-observer agreement in endoscopic scoring systems: preliminary report of an ongoing study from the Italian Group for Inflammatory Bowel Disease (IG-IBD). | Endoscopic activity has become a therapeutic endpoint in inflammatory bowel disease. Aim of this study was to evaluate inter-observer agreement for endoscopic scores in a real-life setting. 14 gastroenterologists with experience in inflammatory bowel disease care and endoscopic scoring reviewed videos of ulcerative col... | 25,154,049 | [
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0.07482594,
0.009343074,
0.1407985,
-0.09072... |
Insights into the pathways of iron- and sulfur-oxidation, and biofilm formation from the chemolithotrophic acidophile Acidithiobacillus ferrivorans CF27. | The iron-oxidizing acidithiobacilli cluster into at least four groups, three of which (Acidithiobacillus ferrooxidans, Acidithiobacillus ferridurans and Acidithiobacillus ferrivorans) have been designated as separate species. While these have many physiological traits in common, they differ in some phenotypic character... | 25,154,051 | [
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0.3792407,
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... |
Elevated elephant density does not improve ecotourism opportunities: convergence in social and ecological objectives. | In order to sustainably conserve biodiversity, many protected areas, particularly private protected areas, must find means of self-financing. Ecotourism is increasingly seen as a mechanism to achieve such financial sustainability. However, there is concern that ecotourism operations are driven to achieve successful gam... | 25,154,086 | [
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0.08968443,
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0.3196497,
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Relationship of habitat variability to population size in a stream fish. | The relationship between habitat variability and population size in fragmented habitats is poorly understood, yet might have important evolutionary consequences. For instance, fragmentation could (1) shift habitat characteristics, and by extension, selective regimes, in a consistent direction as populations and the fra... | 25,154,098 | [
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0.1633137,
0.3649631,
0.1914407,
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0.2075514,
-0.09913721... |
Using Wolbachia-based release for suppression of Aedes mosquitoes: insights from genetic data and population simulations. | A novel strategy for suppressing disease transmission by Aedes aegypti, the main vector of dengue, uses releases of mosquitoes infected with the bacterium Wolbachia pipientis. Wolbachia are currently released to interfere with viral transmission, but there is also potential to use strains in mosquito suppression and el... | 25,154,109 | [
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0.04151621,
0.1625358,
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0.1290538,
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Becoming an occupational therapist: perceived influence of international fieldwork placements on clinical practice. | Many occupational therapy programs have augmented curricula to provide students with opportunities to engage in international fieldwork placements (IFPs). However, limited research exists exploring the perceived influence that IFPs may have on future occupational therapy roles and characteristics. The purpose of this s... | 25,154,131 | [
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[Guidelines for the diagnosis and treatment of hereditary angioedema]. | Hereditary angioedema (HAE) is a rare but potentially fatal genetic disorder with nonpitting, nonerythematous, and not pruritic swelling which can affect the hands, feet, face, genitals and visceral mucosa. The type, frequency, and severity of the attacks vary between patients, and over the lifetime of an individual pa... | 25,154,179 | [
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0.1909424,
0.09594472,
0.236153,
-0.2530186,
... |
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