title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
|---|---|---|---|
[Gaucher disease--guidelines for diagnosis and management of adult patients]. | Gaucher disease is an autosomal recessive disorder, characterized by decreased levels of the lysosomal enzyme glucocerebrosidase. This deficiency results in a decreased breakdown of this glycosphingolipid glucocerebroside, which accumulates in the lysosomes of the monocyte-macrophage system. It is the most common form ... | 25,154,180 | [
0.07137796,
-0.1986501,
0.02641712,
0.01110176,
0.1676454,
-0.2046284,
-0.1605923,
0.01377949,
-0.4689019,
-0.1567439,
0.1172173,
-0.1741125,
-0.2045354,
0.006557708,
-0.4404145,
-0.081434,
-0.4599005,
0.0238882,
0.07323488,
0.2267712,
0.1409677,
0.2900797,
-0.03180687,
... |
[The Polish Task Force position statement on safety of biologic treatment with monoclonal antibodies and soluble receptors]. | The introduction of biologic therapies for treatment in many fields of medicine such as rheumatology oncology, dermatology, hematology and allergology, became one of the most important achievements of the modem medicine. The first biological therapeutics have already reached patent expiration date and corresponding bio... | 25,154,192 | [
-0.1281466,
0.04069543,
0.1053014,
-0.2234502,
-0.03720303,
-0.1373288,
0.1953307,
0.550211,
-0.07956479,
0.1805214,
-0.1701294,
-0.5561906,
0.05473572,
-0.08000356,
-0.3163654,
0.0196412,
-0.05008321,
0.01328385,
-0.02008661,
0.1987601,
0.3025632,
0.2951454,
-0.2783583,
... |
[Fecal lactoferrin in identifying and management of inflammatory bowel disease]. | Inflammatory bowel disease is a group of chronic inflammatory conditions of gastrointestinal tract, including ulcerative colitis and Crohn's disease. Diagnosis of inflammatory bowel disease is based on clinical symptoms, lower and/or upper gastrointestinal tract endoscopy with biopsies and histological results. These p... | 25,154,203 | [
-0.1737555,
0.09589105,
0.2224559,
-0.07936806,
0.02822984,
-0.3478936,
-0.1981872,
-0.00325841,
0.1366721,
-0.2783979,
-0.179044,
-0.08095916,
0.1539764,
-0.2371809,
-0.2338035,
-0.03673077,
-0.572613,
-0.2359377,
0.1041641,
0.06237809,
-0.2790253,
-0.05738484,
-0.189714... |
[Socio-demographic differences in the prevalence of cardiovascular diseases among women and men in Poland--results from the Courage in Europe Project]. | The aim of the study was to assess differences in cardiovascular diseases (CVD) (hypertension, coronary artery disease - CAD, stroke) in women and men in relation to demographic and social characteristics in adult population in Poland. Study was performed in the representative group of 4071 individuals (18+) in Poland.... | 25,154,206 | [
0.09925376,
-0.02121434,
0.1099667,
0.2715797,
0.1794678,
-0.2668613,
-0.02475316,
-0.01163426,
-0.2573267,
0.03195255,
0.1820526,
0.3620211,
-0.02659051,
-0.2041857,
-0.2038501,
0.02938611,
-0.1519162,
0.5894637,
-0.1455335,
0.488453,
0.2904099,
0.3511139,
-0.2270723,
... |
[Difficulties in diagnostics in rhythm disturbances in women]. | Available data suggest that there is a disconnect in the way physicians diagnose and treat heart disease in women versus men. Such situation leads to higher cardiovascular risk in women. On the one hand there are no rhythm disturbances exclusively characteristic for females, but on other hand there are important gender... | 25,154,211 | [
-0.02599813,
-0.07791693,
-0.1004426,
-0.2221699,
0.1089327,
-0.3618116,
0.03069059,
-0.1694972,
0.1674995,
0.04144486,
0.1624276,
0.3767804,
0.1234976,
-0.3253112,
-0.3419305,
-0.3121506,
-0.206661,
0.1701151,
-0.1791953,
0.1464443,
0.193284,
0.038991,
-0.2394899,
0.20... |
[Maternal arrhythmias during pregnancy. Practical review]. | Pregnancy is accompanied by a variety of cardiovascular changes in normal women, and these changes can increased incidence of maternal cardiac arrhythmias. Supraventricular and ventricular arrhythmias reguiring treatment are rarely seen during pregnancy in healthy women. Structural cardiac defects or residual defects a... | 25,154,218 | [
-0.1555845,
0.1050078,
-0.4444116,
-0.1082293,
0.2932495,
-0.3739659,
-0.306464,
-0.3271424,
0.2075661,
-0.1082091,
0.1478441,
0.01281347,
-0.2461901,
0.12481,
-0.1443428,
-0.1571246,
-0.4626611,
0.107752,
0.02202859,
-0.006316117,
-0.2000535,
0.320194,
-0.2839799,
-0.0... |
[Current surgical management of cancer of the ampulla of Vater]. | Pancreatoduodenectomy (PD) is the standard radical treatment for cancer of the ampulla of Vater. Among patients we have treated in whom lymph node metastasis of cancer of the ampulla of Vater occurred, more positive lymph nodes surrounding the superior mesenteric artery were seen in one (patient No. 14), whereas more p... | 25,154,238 | [
-0.01919415,
-0.2561553,
-0.2121567,
-0.2335237,
-0.01678188,
-0.3593293,
-0.03403376,
0.05392767,
-0.07131115,
0.3174678,
0.1813744,
-0.1046489,
0.07769025,
-0.4588691,
-0.4858801,
-0.2669554,
-0.2204459,
0.2989402,
0.1233982,
0.2204984,
0.2704139,
-0.02581182,
-0.042242... |
[Concept of perihilar cholangiocarcinoma in the General Rules for Clinical and Pathological Studies on Cancer of the Biliary Tract, 6th edition]. | Hilar cholangiocarcinoma is clinically characterized by biliary obstruction in the porta hepatis. Because the boundary between the intrahepatic and extrahepatic bile duct is unclear, hilar cholangiocarcinoma can potentially arise from both ducts. Therefore, the definition of hilar cholangiocarcinoma remains under debat... | 25,154,239 | [
-0.004260388,
0.03902374,
0.07144931,
-0.1753767,
0.1107077,
-0.277625,
0.0594271,
0.0369995,
0.1314709,
0.3559366,
-0.1028874,
-0.1742181,
-0.01524657,
0.1179454,
-0.490906,
-0.487054,
0.07832703,
0.393151,
0.3271458,
-0.3449279,
0.03105285,
0.0237303,
-0.01391541,
0.1... |
Protective effect of pomegranate seed oil against mercuric chloride-induced nephrotoxicity in rat. | Heavy metals such as mercury can induce the generation of free radicals and oxidative stress which are associated with tissue injury. The present study was designed to evaluate the protective effect of pomegranate seed oil against HgCl2-induced nephrotoxicity. Twenty-four W/A adult rats were randomly divided into four ... | 25,154,291 | [
0.03036893,
0.009850536,
0.04808217,
-0.2884655,
0.2623322,
-0.05026283,
-0.276276,
0.2974116,
-0.003782006,
0.06055892,
0.1370571,
0.4886411,
0.03698177,
-0.01869226,
-0.228268,
0.4289351,
0.02296277,
0.1235757,
0.1670582,
0.185861,
-0.008148408,
-0.08031003,
-0.2262575,... |
Effects of two field continuous incremental tests on cardiorespiratory responses in Standardbred trotters. | In humans, cardiorespiratory responses are widely evaluated from field incremental exercise tests. On the contrary, equine exercise physiology faces a huge lack of oxygen consumption measurements (VO2) in field conditions due to technical concerns. The aim of this study was to test the effects of two incremental contin... | 25,154,293 | [
-0.09147838,
-0.1645739,
-0.4539402,
0.02711488,
-0.08824024,
-0.4000705,
-0.004048281,
-0.3541245,
-0.3383034,
-0.2547055,
-0.08075453,
0.1249878,
-0.06192387,
-0.04438779,
-0.5855097,
-0.5467442,
-0.5262011,
-0.05385843,
-0.1562274,
0.02068709,
-0.02540096,
-0.02765802,
... |
Estimating survival of patients receiving radiosurgery alone for cerebral metastasis from melanoma. | This study aimed to identify clinical factors associated with survival and to develop a prognostic tool in patients receiving radiosurgery alone for very few cerebral metastases from melanoma. Ten characteristics of 69 patients treated with radiosurgery alone for 1-3 cerebral metastases from melanoma were retrospective... | 25,154,301 | [
0.02290333,
-0.2107487,
-0.2507543,
-0.5134319,
0.008449872,
-0.5941634,
0.05909336,
-0.09071447,
-0.2082542,
-0.1324727,
0.003848923,
0.1835377,
0.1542236,
-0.1986111,
-0.308256,
-0.03424923,
0.2083368,
0.3168578,
0.2528976,
0.3268564,
0.2136615,
0.3663606,
-0.08090325,
... |
Feasibility of 8-OHdG formation and hOGG1 induction in PBMCs for assessing oxidative DNA damage in the lung of COPD patients. | Oxidative stress has long been recognized to play a role in chronic obstructive pulmonary disease (COPD); however, approaches for assessing oxidative stress are lacking. The objective of this study was to address the feasibility of measuring 8-oxo-7, 8-dihydro-2'-deoxyguanosine (8-OHdG) formation and human 8-oxoguanine... | 25,154,311 | [
0.08699128,
-0.1024157,
-0.02460501,
-0.02088443,
0.01664465,
-0.2125365,
-0.2214384,
0.06654204,
0.1449302,
-0.2791404,
-0.02442849,
0.005746397,
-0.006839316,
-0.02603444,
-0.04292009,
-0.1169918,
-0.4597425,
0.2109002,
0.1701617,
0.1543165,
-0.08766235,
0.3386394,
-0.0... |
Etiology and outcomes for patients infected with HIV in intensive care units in a tertiary care hospital in China. | Although the National Free Antiretroviral Treatment Program (NFATP) has resulted in a significant reduction in the incidence of AIDS-defining illnesses in China, severe complications in patients infected with HIV may require aggressive treatment and critical care support. The objective for this study was to investigate... | 25,154,318 | [
0.1341917,
0.1797299,
-0.1382482,
-0.02744106,
-0.237357,
0.08009688,
-0.1487114,
0.1055854,
0.02037503,
0.4472403,
0.2369843,
-0.4558449,
0.1955155,
0.1911155,
-0.3027601,
-0.04726424,
-0.1722983,
-0.1302002,
0.2310851,
0.02468322,
0.003567507,
0.4269058,
-0.1116192,
0... |
Charge-induced phase separation in lipid membranes. | Phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of unsaturated neutral lipid, dioleoylphosphatidylcholine (DOPC), saturated neutr... | 25,154,325 | [
0.007434702,
0.3239899,
-0.3351913,
-0.04235718,
0.07895675,
-0.101195,
-0.1427652,
0.1073097,
0.2239016,
0.08608019,
-0.1860661,
-0.2988598,
-0.07623427,
0.140626,
-0.409158,
-0.2424695,
-0.574985,
-0.02398788,
-0.04990963,
-0.08202679,
0.1935469,
0.08592326,
0.03521499,... |
Relationships of intraosseous and systemic pressure waveforms in a Swine model. | Despite some focus on the use of intraosseous (IO) catheters to obtain laboratory samples, very little is known about the potential for obtaining other forms of clinical data. Largely unstudied is the relationship between IO pressures (IOPs) and systemic hemodynamic pressures such as mean arterial pressure (MAP) and ce... | 25,154,326 | [
-0.03730536,
-0.003154224,
-0.1389423,
-0.2527072,
-0.2554622,
-0.369744,
-0.4038683,
-0.207129,
0.01231792,
-0.1792703,
0.2200572,
-0.2982806,
-0.01570079,
-0.1590669,
-0.2366078,
-0.2592886,
-0.708861,
0.07176051,
-0.262085,
0.2906084,
-0.007166678,
-0.006760193,
0.0894... |
Clinical experience of anti-Xa monitoring in critically ill dogs receiving dalteparin. | To describe a population of critically ill dogs receiving dalteparin monitored with an anti-Xa assay, to assess the potential utility of serial monitoring, and to investigate the association between pre-treatment thromboelastography (TEG) and the ability to achieve targeted anti-Xa activity. Descriptive retrospective s... | 25,154,357 | [
0.1613156,
0.1202163,
-0.1684935,
-0.3455229,
-0.1505508,
-0.2278895,
0.4479443,
-0.03603428,
-0.2634531,
-0.2467791,
0.04187916,
-0.007822174,
-0.1226669,
-0.340619,
0.01775814,
0.2585366,
-0.1924513,
0.238401,
0.3959879,
0.002595941,
0.06866076,
0.03228545,
-0.01417312,... |
Role of allogeneic stem cell transplantation in mantle cell lymphoma. | Despite a wide spectrum of treatment options, mantle cell lymphoma (MCL) remains a challenging hematologic malignancy to manage. Advances in front-line therapy, including the monoclonal antibody rituximab and increasing use of cytarabine, have improved remission rates. Autologous hematopoietic cell transplantation (HCT... | 25,154,430 | [
-0.07814103,
-0.101988,
-0.0491816,
-0.5788466,
0.07278308,
0.0004754559,
0.1046435,
0.3380727,
-0.1474523,
0.2952182,
0.106996,
0.08771104,
0.05854199,
0.1868388,
0.04165877,
-0.2517209,
-0.1699676,
0.210407,
-0.03122902,
-0.3043062,
0.3559691,
0.1537633,
-0.1094705,
-... |
A comparison of assessments and relationships of stress of conscience, perceptions of conscience, burnout and social support between healthcare personnel working at two different organizations for care of older people. | The aim of this cross-sectional, descriptive study was to compare assessments and relationships of stress of conscience, perceptions of conscience, burnout and social support between healthcare personnel (HCP) working in two different organisations for care of older people. This cross-sectional, descriptive comparative... | 25,154,457 | [
0.04228115,
0.1569737,
0.1588419,
0.2541098,
-0.1443266,
-0.2509871,
-0.03828857,
-0.1640953,
-0.1921447,
0.2470379,
-0.07731203,
-0.1119045,
-0.2135091,
-0.1111799,
-0.09919949,
-0.368552,
-0.4160997,
0.3612522,
0.2801196,
-0.180646,
-0.08527422,
0.1808791,
0.02031665,
... |
Effective charge separation in the rutile TiO2 nanorod-coupled α-Fe2O3 with exceptionally high visible activities. | Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attrib... | 25,154,460 | [
0.06647512,
-0.05997042,
0.002009669,
-0.009809484,
-0.221262,
-0.2533375,
-0.1821406,
-0.1654035,
0.01317862,
0.1399121,
-0.213653,
0.09447625,
-0.07544381,
0.007895462,
-0.4549163,
-0.2227727,
-0.8353575,
0.194481,
0.03467968,
-0.04850479,
-0.09452614,
0.2210696,
-0.136... |
Lysosomal pH rise during heat shock monitored by a lysosome-targeting near-infrared ratiometric fluorescent probe. | Heat stroke is a life-threatening condition, featuring a high body temperature and malfunction of many organ systems. The relationship between heat shock and lysosomes is poorly understood, mainly because of the lack of a suitable research approach. Herein, by incorporating morpholine into a stable hemicyanine skeleton... | 25,154,475 | [
-0.2461898,
-0.08914439,
-0.2800094,
0.3010588,
-0.1069809,
0.1016166,
0.09840793,
-0.05749877,
0.05893862,
0.06060295,
-0.1618759,
0.04655161,
0.07694779,
-0.1603209,
-0.3780462,
-0.1794493,
-0.463001,
0.3057346,
-0.2092032,
0.1846373,
0.420698,
0.1499829,
-0.129216,
0... |
Complex-shaped microbial biominerals for nanotechnology. | Single-celled microorganisms such as diatoms and coccolithophores produce inorganic microparticles with genetically controlled hierarchical nanopatterns. Besides serving as paradigms to inspire new routes for materials synthesis, biominerals themselves, particularly diatom biosilica, are increasingly utilized as templa... | 25,154,474 | [
-0.1967344,
-0.15069,
0.130016,
0.1394878,
-0.3933672,
-0.1029453,
-0.6783609,
0.02122205,
0.3818973,
-0.006105997,
-0.1445499,
-0.3072048,
-0.1925118,
-0.3026085,
-0.6788726,
0.01221169,
-0.5130438,
0.002420762,
0.1233491,
-0.03997669,
0.04871573,
0.2961625,
-0.2914131,
... |
Use of the 2-μm continuous wave thulium laser for the resection of oral squamous cell carcinomas does not impair pathological assessment. | Current resection modalities for oral squamous cell carcinomas (OSCC) vary from cold steel over CO2 laser to monopolar electro-surgery (MO). We compared thulium laser (TL) as a new modality with MO with regards to pathological assessment. Forty-two patients who were treated for OSCC by either TL or MO were included. Al... | 25,154,492 | [
-0.08779184,
-0.03427104,
-0.2975342,
-0.3982746,
-0.3501693,
-0.4274725,
-0.04345267,
0.08283386,
0.1617271,
0.1979871,
-0.07768937,
0.33423,
0.05227434,
-0.5652305,
-0.3037913,
-0.3575476,
0.0003125954,
0.06468534,
-0.04497312,
0.06453227,
0.3901308,
0.5582449,
0.047042... |
Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals. | Environmental factors routinely influence an organism's biology. The inheritance or transmission of such influences to descendant generations would be an efficient mode of information transfer across generations. The developmental stage at which a specific environment is encountered by the ancestral generation, and the... | 25,154,497 | [
0.01580064,
-0.172567,
-0.0174551,
-0.1314315,
-0.003489313,
-0.3729236,
-0.1254163,
-0.1384993,
-0.05353959,
-0.009811893,
-0.1273236,
-0.04610925,
0.1808311,
0.108328,
-0.3739763,
0.1256217,
-0.3594591,
-0.2085076,
-0.2880283,
-0.1328191,
-0.1799091,
0.2405199,
-0.26153... |
New targets for antibody therapy of pediatric B cell lymphomas. | Antibody therapy has become standard of care for adult B cell lymphoma patients. It is a potentially less toxic and more targeted approach for lymphoma therapy and should therefore be applied to treat pediatric B cell lymphoma patients as well. In pediatric lymphoma patients, however, clinical experience with monoclona... | 25,154,500 | [
-0.1604972,
-0.1102513,
-0.180888,
-0.3350097,
-0.08225372,
-0.1334778,
-0.2036731,
0.1340564,
-0.05008928,
0.3615212,
0.1324273,
0.1188534,
0.2367687,
-0.05871214,
-0.4194666,
-0.02215432,
-0.3196818,
0.2239229,
-0.1356841,
0.2521835,
0.1928536,
0.2647749,
-0.09558319,
... |
Multilevel analyses of school and children's characteristics associated with physical activity. | Children spend most of their awake time at school, and it is important to identify individual and school-level correlates of their physical activity (PA) levels. This study aimed to identify the between-school variability in Portuguese children PA and to investigate student and school PA correlates using multilevel mod... | 25,154,531 | [
0.02506057,
0.1518811,
-0.2091494,
0.2145133,
-0.05267065,
-0.3796986,
-0.3310831,
-0.4077615,
-0.26092,
-0.05258414,
0.4711435,
0.06582896,
-0.2371587,
-0.3217546,
-0.3985974,
0.1144859,
-0.01431662,
0.05084623,
0.04699009,
0.10133,
0.01947426,
-0.1272515,
-0.1697047,
... |
Risk and protective factors for depression that adolescents can modify: a systematic review and meta-analysis of longitudinal studies. | Adolescence is a peak time for the onset of depression, but little is known about what adolescents can do to reduce their own level of risk. To fill this gap, a review was carried out to identify risk and protective factors for depression during adolescence that are modifiable by the young person. Employing the PRISMA ... | 25,154,536 | [
-0.3202536,
0.1783363,
-0.2702526,
0.05595245,
0.2593739,
-0.3842199,
-0.3869669,
-0.3670401,
0.05072891,
-0.1904911,
0.1210449,
0.07180879,
-0.0376731,
-0.2710716,
-0.2489926,
0.08648591,
-0.1518421,
0.3064998,
-0.1024971,
0.07643925,
-0.3328555,
-0.1616023,
-0.1845484,
... |
Comparison of methods used for assessing the viability and vitality of yeast cells. | Determination of cell viability is the most commonly used method for assessing the impact of various types of stressors in toxicity research and in industrial microbiology studies. Viability is defined as a percentage of live cells in a whole population. Although cell death is one of the consequences of toxicity, chemi... | 25,154,541 | [
0.03829803,
-0.2079002,
0.1480523,
-0.02509896,
-0.04137695,
-0.004680327,
0.3354444,
0.2408241,
0.176348,
-0.2439135,
-0.09845479,
-0.2055849,
-0.2911041,
0.03080241,
-0.4713639,
-0.06327248,
-0.1480502,
0.1089194,
0.0514963,
0.3425792,
0.2709049,
0.5772104,
-0.02952656,... |
Supportive relationships within ongoing families: cross-lagged effects between components of support and adjustment in parents and young adult children. | Italy is the first country in which the phenomenon of cohabitation of parents and young adult children was examined. From the earliest studies, it seemed clear that the transition to adulthood occurs within the family of origin: indeed, the successful outcome of this transition depends on the quality of family relation... | 25,154,544 | [
0.02078021,
-0.09719175,
-0.0731192,
0.01776957,
0.2925752,
-0.1980798,
-0.1451088,
-0.03836668,
-0.1404855,
0.1019711,
-0.2798119,
-0.1680568,
-0.1974689,
-0.3676558,
-0.6207185,
-0.4143524,
0.1292006,
0.1651854,
-0.01785425,
-0.02341275,
0.04070532,
0.2718344,
-0.025893... |
Occupation and its relationship with health and wellbeing: the threshold concept for occupational therapy. | We introduce the educational framework of 'threshold concepts' and discuss its utility in understanding the fundamental difficulties learners have in understanding ways of thinking and practising as occupational therapists. We propose that the relationship between occupation and health is a threshold concept for occupa... | 25,154,548 | [
-0.2400671,
-0.05842117,
-0.09745935,
-0.1496771,
0.05772479,
-0.365218,
0.3141277,
0.1030171,
0.1133034,
0.1488319,
0.1358968,
-0.2305596,
-0.2279991,
-0.115909,
-0.4821318,
-0.01440963,
-0.4685149,
-0.006764757,
-0.5437786,
-0.08312353,
0.02557097,
0.4818511,
-0.2469981... |
Endovascular balloon occlusion is associated with reduced intraoperative mortality of unstable patients with ruptured abdominal aortic aneurysm but fails to improve other outcomes. | Proximal aortic control by endovascular balloon occlusion (EBO) is an alternative to conventional aortic cross-clamping (CAC) in hemodynamically unstable patients presenting with a ruptured abdominal aortic aneurysm (rAAA). The aim of this study was to evaluate the potential clinical benefit of EBO over CAC. Data from ... | 25,154,564 | [
0.1830475,
0.2774448,
-0.2878039,
-0.3544602,
-0.141395,
-0.2315262,
-0.007757631,
-0.2429832,
0.06430347,
-0.0490431,
0.1479568,
0.1127558,
0.1115573,
-0.3084317,
-0.02221266,
-0.02631803,
-0.6943413,
0.03375152,
0.04615537,
-0.1715404,
-0.07459424,
0.286992,
0.006695086... |
Functional connectivity of hippocampal and prefrontal networks during episodic and spatial memory based on real-world environments. | Several recent studies have compared episodic and spatial memory in neuroimaging paradigms in order to understand better the contribution of the hippocampus to each of these tasks. In the present study, we build on previous findings showing common neural activation in default network areas during episodic and spatial m... | 25,154,600 | [
0.03534061,
0.327585,
-0.1495659,
0.05424619,
0.1800388,
-0.2604981,
-0.1263018,
-0.1389462,
-0.111321,
0.1771586,
0.0441339,
0.08993039,
-0.03001127,
-0.2204672,
-0.2329264,
-0.2482009,
0.009400316,
0.442162,
-0.1125681,
-0.1794741,
-0.196901,
0.224063,
-0.0862326,
0.0... |
Antiretroviral therapy response among HIV-2 infected patients: a systematic review. | Few data are available on antiretroviral therapy (ART) response among HIV-2 infected patients. We conducted a systematic review on treatment outcomes among HIV-2 infected patients on ART, focusing on the immunological and virological responses in adults. Data were extracted from articles that were selected after screen... | 25,154,616 | [
-0.1938769,
-0.18349,
-0.3191892,
-0.2447911,
0.01452112,
-0.1395685,
0.007611125,
0.1478378,
0.2191776,
-0.1623834,
0.01123896,
-0.1504802,
0.1784959,
0.2711193,
-0.3829652,
-0.4758368,
-0.3956631,
0.1584202,
-0.08967549,
0.2581724,
-0.01989549,
0.3317283,
-0.3467906,
... |
Soluble urokinase-type plasminogen activator receptor levels in patients with schizophrenia. | The etiology of schizophrenia remains largely unknown but alterations in the immune system may be involved. In addition to the psychiatric symptoms, schizophrenia is also associated with up to 20 years reduction in life span. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that can be measure... | 25,154,621 | [
0.1611259,
-0.2946485,
-0.1241892,
-0.2439707,
0.270326,
-0.3388662,
0.06340504,
0.2722696,
-0.126318,
0.3393159,
-0.04798911,
0.03476522,
0.05927589,
-0.0009823358,
0.3686807,
0.09547024,
0.1089423,
0.01257538,
0.1943586,
0.1633406,
0.1232962,
0.474975,
-0.1646764,
-0.... |
Comparison of two comorbidity scoring systems for older adults with traumatic injuries. | The purpose of this study was to determine the mortality predictive value of two different comorbidity scores, Comorbidity-Polypharmacy Score (CPS) and Charlson scoring system, in a large sample of older trauma patients. At an urban tertiary care Level I trauma center, trauma patients aged 55 years and older who were i... | 25,154,672 | [
0.1253585,
-0.05647005,
-0.1095734,
-0.2007029,
-0.06834643,
-0.114174,
-0.0698005,
0.2885309,
-0.1303489,
0.009398758,
-0.09479773,
0.2762842,
0.1247361,
-0.1077018,
-0.1400979,
-0.2580479,
0.1963962,
0.1578524,
0.147368,
0.1670323,
-0.3012416,
-0.1158893,
-0.09674198,
... |
Trends in organ donor management: 2002 to 2012. | Refinements in donor management have resulted in increased numbers and quality of grafts after neurologic death. We hypothesize that the increased use of hormone replacement therapy (HRT) has been accompanied by improved outcomes over time. Using the Organ Procurement and Transplant Network donor database, all brain-de... | 25,154,673 | [
-0.1800621,
-0.2211526,
0.1235165,
-0.4127635,
0.2275123,
-0.5809619,
0.09370659,
0.2351114,
-0.3829473,
0.1441486,
0.04375203,
0.1296136,
-0.01815625,
-0.2132669,
-0.2603846,
-0.08338901,
-0.02535436,
-0.1996236,
0.1573862,
0.01711609,
-0.1226117,
0.4632773,
-0.06050959,... |
Prospective study of depression and anxiety in female fertility preservation and infertility patients. | To prospectively assess anxiety, depression, coping, and appraisal in female fertility preservation (FP) patients compared with infertile patients. Prospective pre- and post-treatment survey. Academic medical center. Forty-seven women with cancer (FP patients) and 91 age-matched infertile patients. None. Depression, an... | 25,154,674 | [
-0.075895,
-0.04603986,
-0.04070868,
-0.163688,
-0.06675035,
-0.3482142,
0.2097189,
0.4106408,
-0.06400575,
0.006461054,
0.03515043,
0.2078706,
-0.07716443,
-0.2313436,
0.0169415,
-0.2990844,
0.02265679,
0.1200006,
0.01733383,
-0.1229094,
-0.5080015,
0.2686886,
-0.1580494... |
Blastocyst euploidy and implantation rates in a young (<35 years) and old (≥35 years) presumed fertile and infertile patient population. | To examine the relationship between blastocyst euploidy and implantation rates in a presumed fertile patient population. Retrospective analysis. Private IVF clinic. IVF patients undergoing comprehensive chromosome screening (CCS). Embryo biopsy at the blastocyst stage with preimplantation genetic screening using CCS. E... | 25,154,676 | [
0.006044583,
0.2322056,
0.07071081,
-0.01534785,
0.08052137,
0.1181015,
0.1220274,
0.07588129,
0.3897775,
0.004194038,
0.2574194,
0.3448763,
-0.1782079,
0.06396618,
-0.04293793,
-0.2708881,
-0.2692928,
0.08523382,
-0.1316032,
-0.2220167,
0.06353853,
0.2978937,
-0.1214513,... |
[Functional diarrhea - pathophysiology, investigation and treatment]. | The most important reason for functional diarrhea in clinical practice is diarrhea-predominant irritable bowel syndrome (IBS) which is characterized by chronic intermittent diarrhea and abdominal pain. The pathophysiology underlying IBS is complex and includes visceral hypersensitivity, abnormal gut motility and autono... | 25,154,691 | [
-0.1326949,
0.08975241,
0.2366394,
0.04443568,
0.2993983,
-0.2430203,
-0.01118771,
0.07550522,
0.126554,
-0.06746905,
0.1976705,
-0.07926548,
-0.19157,
-0.1244732,
-0.368349,
-0.2449792,
-0.7871019,
0.1382948,
-0.1135227,
0.1543105,
-0.1469898,
0.1910897,
-0.1456411,
-0... |
PLASTID MOVEMENT IMPAIRED1 mediates ABA sensitivity during germination and implicates ABA in light-mediated Chloroplast movements. | The plant hormone abscisic acid (ABA) controls many aspects of plant growth and development, including seed development, germination and responses to water-deficit stress. A complex ABA signaling network integrates environmental signals including water availability and light intensity and quality to fine-tune the respo... | 25,154,696 | [
-0.01673463,
0.1970932,
0.1103421,
-0.2776732,
0.1934323,
-0.1769138,
-0.1772303,
0.3789385,
-0.1729755,
-0.3815832,
0.289183,
0.0683317,
-0.4799474,
-0.05614554,
0.1660281,
0.3223907,
-0.4875375,
0.250337,
0.05739707,
-0.1250986,
0.7852947,
0.2295078,
0.04975025,
-0.40... |
Impaired 6-min walk test, heart rate recovery and cardiac function post pulmonary embolism in long-term survivors. | The functional capacity of long-term survivors of submassive pulmonary embolism (PE) is unreported. A six-minute walk distance (6MWD) <350 m and reduced heart rate recovery (HRR) indicate adverse prognosis in various chronic diseases. Long-term survivors of acute PE (January 2000-June 2005) were invited to undergo p... | 25,154,698 | [
0.005686304,
-0.2176829,
-0.4408539,
-0.1887956,
-0.2050976,
-0.4748959,
-0.1068741,
-0.02126518,
-0.07397601,
-0.1037226,
-0.008306325,
0.5534411,
-0.1992082,
-0.1174647,
0.0594153,
-0.1179751,
0.07648647,
0.1913959,
0.1017434,
0.01826948,
-0.4873012,
0.08423966,
-0.3092... |
The effect of baicalin in a mouse model of retinopathy of prematurity. | Baicalin is a flavonoid derived from the dried root of Scutellaria baicalensis. In this study, oxygen-induced retinopathy was used to characterize the anti-angiogenic properties of baicalin in mice. Pups were exposed to a hyperbaric oxygen environment to induce retinal angiogenesis and were subjected to intraperitoneal... | 25,154,719 | [
-0.1070659,
0.04079048,
-0.1326744,
0.4935179,
0.1956758,
-0.05820136,
0.2965487,
-0.01383417,
0.3957901,
-0.2668135,
0.01734942,
0.230082,
-0.3205224,
-0.1836632,
-0.132719,
0.1558889,
0.05238757,
0.401624,
0.09261953,
-0.1366644,
0.08021199,
0.2932004,
-0.2156895,
-0.... |
Non-ablative fractional laser provides long-term improvement of mature burn scars--a randomized controlled trial with histological assessment. | Non-ablative fractional laser-treatment is evolving for burn scars. The objective of this study was to evaluate clinical and histological long-term outcome of 1,540 nm fractional Erbium: Glass laser, targeting superficial, and deep components of mature burn scars. Side-by-side scar-areas were randomized to untreated co... | 25,154,734 | [
0.194985,
0.3230481,
-0.1046102,
-0.01427271,
-0.1611135,
-0.3139498,
0.2567663,
0.1123875,
0.09980416,
-0.01382519,
0.02840474,
-0.1087839,
-0.2327892,
-0.3319545,
-0.5336957,
-0.1236665,
0.08054933,
0.01181353,
-0.06107394,
-0.1802001,
-0.1113043,
0.2138122,
-0.2112087,... |
Investigation of DNA repair gene variants on myelodysplastic syndromes in a Turkish population. | The aim of this study was to assess the possible influence of genetic polymorphisms in hOGG1, XRCC1, XRCC3, XPD, XPG and APE1 on the observed DNA damage in a group of Turkish myelodysplastic syndrome (MDS) patients. A total of 39 patients with myelodysplastic syndrome and 78 age-matched healthy control subjects were in... | 25,154,760 | [
0.1519728,
-0.3266057,
0.1811503,
0.1167646,
-0.209678,
-0.2591441,
0.2205368,
-0.1513174,
0.04203418,
0.3089812,
0.2398985,
0.2062988,
-0.3192031,
0.1093512,
-0.4200918,
-0.3485678,
-0.4452932,
0.3062971,
0.078382,
0.3121698,
0.1682047,
0.1464543,
0.038451,
0.06724895,... |
Live birth after PGD with confirmation by a comprehensive approach (karyomapping) for simultaneous detection of monogenic and chromosomal disorders. | Preimplantation genetic diagnosis (PGD) for monogenic disorders has the drawback of time and cost associated with tailoring a specific test for each couple, disorder, or both. The inability of any single assay to detect the monogenic disorder in question and simultaneously the chromosomal complement of the embryo also ... | 25,154,779 | [
0.1448333,
0.02774215,
0.2918444,
0.1660848,
0.1915113,
-0.2618866,
-0.2010114,
-0.2242067,
0.3748369,
-0.0840678,
0.0632249,
0.4259004,
-0.2587644,
0.3569189,
-0.1994708,
-0.2784384,
-0.5818825,
-0.219955,
0.02949429,
-0.3160024,
0.2645333,
0.3721713,
-0.03932653,
0.04... |
Identification of a breast cancer family double heterozygote for RAD51C and BRCA2 gene mutations. | Next-generation sequencing has entered routine genetic testing of hereditary breast cancer. It has provided the opportunity to screen multiple genes simultaneously, and consequently has identified new complex genotypes. Here we report the first identification of a woman double heterozygote for mutations in the RAD51C a... | 25,154,786 | [
-0.05462464,
0.09429966,
-0.0127981,
-0.4297926,
0.03165649,
-0.00519512,
0.266367,
0.1110679,
0.03017283,
0.002968968,
0.2232352,
0.4358804,
-0.3836228,
0.0004577071,
-0.2348865,
-0.476633,
-0.1802776,
0.08468947,
0.1810728,
-0.1898505,
0.3462714,
0.4675667,
-0.03580197,... |
Systematic review of various laser intervention strategies for proliferative diabetic retinopathy. | Diabetic retinopathy (DR) is a common complication of diabetes. DR obstructs blood supply to the retina and has serious and long-lasting detrimental effects on quality of life. Panretinal photocoagulation, a laser surgical intervention, is advocated for early treatment of DR to prevent visual loss; however, results fro... | 25,154,790 | [
0.0586308,
-0.06920673,
-0.1256144,
-0.03352864,
0.1016515,
-0.3379818,
0.09217809,
0.01531566,
0.04700981,
0.145708,
0.002060106,
0.0854267,
-0.1994224,
-0.152825,
0.1627821,
-0.2004922,
-0.002660825,
0.013998,
0.4336901,
-0.2251942,
-0.1500437,
0.3172576,
-0.1573562,
... |
Magnetic analysis of a tetranuclear octahedral high-spin cobalt(II) complex based on a newly derived magnetic susceptibility equation. | Here we report a versatile magnetic susceptibility equation for tetranuclear octahedral high-spin cobalt(ii) complexes and a magnetic analysis for a tetranuclear defect cubane cobalt(ii) complex based on this equation. We concluded that the interaction is essentially ferromagnetic despite the decrease in the χT product... | 25,154,808 | [
-0.01900958,
-0.1986831,
0.1006065,
0.08713012,
0.1114916,
-0.08032293,
-0.3375769,
-0.1957919,
0.2747516,
-0.1208945,
-0.1280164,
0.06559685,
0.0673801,
0.1107872,
-0.8494981,
-0.2449993,
-0.3594547,
0.1373232,
-0.05767992,
0.2540814,
0.150576,
0.01567896,
-0.1566816,
... |
Involvement of an antioxidant defense system in the adaptive response to cadmium in maize seedlings (Zea mays L.). | Chemical and biological analyses were used to investigate the growth response and antioxidant defense mechanism of maize seedlings (Zea mays L.) grown in soils with 0-100 mg kg(-1) Cd. Results showed that maize seedlings have strong abilities to accumulate and tolerate high concentrations of Cd. For soil with 50 mg kg(... | 25,154,813 | [
0.3108876,
-0.08455653,
0.07592148,
-0.1112102,
0.1947366,
-0.1474568,
-0.3471683,
-0.07645298,
-0.3239016,
0.1411986,
-0.08011394,
0.2042035,
-0.1142042,
0.3516853,
-0.2882842,
0.2353788,
-0.09317964,
0.5710022,
0.08163472,
0.07089932,
0.2815947,
0.5441781,
-0.2540381,
... |
Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522. | Combining cisplatin or cetuximab with radiation improves overall survival (OS) of patients with stage III or IV head and neck carcinoma (HNC). Cetuximab plus platinum regimens also increase OS in metastatic HNC. The Radiation Therapy Oncology Group launched a phase III trial to test the hypothesis that adding cetuximab... | 25,154,822 | [
0.1362776,
-0.1650353,
-0.0006137171,
-0.2201519,
0.09433278,
-0.4479395,
0.03612097,
0.1405057,
0.06987003,
0.08523153,
-0.1289726,
0.3741654,
-0.1124645,
-0.2857933,
-0.2746862,
-0.4666795,
-0.1575446,
0.2287056,
-0.00626286,
0.01357278,
0.1066902,
0.1210411,
-0.2339554... |
Effects of enamel fluorosis and dental caries on quality of life. | The objectives of this study were to determine the impact of enamel fluorosis and dental caries on oral health-related quality of life (OHRQoL) in North Carolina schoolchildren and their families. Students (n = 7,686) enrolled in 398 classrooms in grades K-12 were recruited for a onetime survey. Parents of students in ... | 25,154,834 | [
-0.309793,
0.1169243,
0.1079516,
0.5353513,
-0.004540571,
-0.2899913,
-0.3229632,
0.2211906,
0.04818538,
-0.04300777,
0.0529521,
0.1811333,
-0.1970876,
-0.12324,
-0.1868733,
-0.685713,
-0.04605241,
-0.01146874,
-0.1405103,
-0.0199014,
0.08541705,
0.5528402,
-0.006149676,
... |
[Application of percutaneous pedicle screw fixation for lumbar degenerative disease]. | To evaluate the accuracy and safety of mini-invasive and percutaneous pedicle screw fixation with fluoroscopy for lumbar degenerative disease. For this retrospective study, 64 cases of lumbar degenerative disease underwent mini-invasive transforaminal lumbar interbody fusion (TLIF) under microscope plus percutaneous pe... | 25,154,836 | [
-0.01147504,
0.1039997,
-0.003144733,
0.1665619,
-0.1037693,
-0.409073,
-0.01040367,
0.0578448,
-0.1255275,
-0.4117448,
0.1171686,
-0.115626,
-0.07902741,
-0.4105456,
-0.2701207,
-0.2798762,
-0.4102176,
0.2812118,
0.2013357,
0.2763176,
0.06267305,
0.3344898,
-0.1853812,
... |
FEN1 -69G>A and 4150G>T polymorphisms and cancer risk in Chinese population. | Previous studies have investigated the associations between FEN1 -69G>A (rs174538) and 4150G>T (rs4246215) polymorphisms and cancer risk in Chinese population. However, the results were controversial. We therefore carried out a meta-analysis to derive a more precise estimation of the associations. PubMed Database... | 25,154,853 | [
-0.03692371,
-0.1530782,
-0.1992725,
-0.1822773,
-0.1481383,
-0.05473547,
-0.1486756,
-0.012465,
0.04891436,
0.2459405,
0.2199856,
0.2099513,
0.06143681,
0.01156135,
-0.3207821,
-0.469346,
-0.6836669,
0.03764611,
0.06935536,
0.3280304,
-0.4526307,
0.4069418,
-0.2613031,
... |
Computed tomographic arthrography of the normal canine elbow. | Comprehensive evaluation of canine elbow joint dysfunction includes assessment of articular cartilage, which can noninvasively be performed with contrast arthrography. Aims of this prospective study were to compare positive contrast computed tomographic (CT) arthrography and histomorphometry measures of cartilage thick... | 25,154,869 | [
-0.1785297,
0.2406195,
0.1377338,
-0.6158466,
-0.06692395,
-0.1128226,
-0.1222188,
0.1886136,
0.02878657,
-0.07093817,
0.1537342,
-0.4011901,
0.2326047,
-0.2607521,
-0.2271869,
0.07827427,
-0.1460437,
0.4314499,
0.01830082,
0.01986692,
-0.009921745,
0.03152354,
0.1274374,... |
Deciphering the unusual HLA-A2/Melan-A/MART-1-specific TCR repertoire in humans. | The Melan-A/MART-1(26-35) antigenic peptide is one of the best studied human tumor-associated antigens. It is expressed in healthy melanocytes and malignant melanoma and is recognized by CD8(+) T cells in the context of the MHC class I molecule HLA-A*0201. While an unusually large repertoire of CD8(+) T cells specific ... | 25,154,881 | [
-0.09973212,
-0.4258701,
-0.2933279,
-0.4637371,
0.1400819,
-0.3142775,
-0.01324793,
0.328092,
0.223764,
0.2828486,
0.1070654,
-0.1035373,
0.2079861,
-0.2354589,
-0.1095383,
-0.05230663,
-0.1284821,
-0.2318452,
0.1406738,
-0.006287447,
0.4034461,
0.3011362,
-0.1395389,
... |
Self-assembly of hybridized ligands on gold nanodots: tunable photoluminescence and sensing of nitrite. | Highly photoluminescent gold nanodots (Au NDs) via etching and co-deposition of hybridized ligands [11-mercaptoundecanol (11-MU) and its complexes with amphiphilic ligands] on gold nanoparticles (∼3 nm) have been prepared and employed for the detection of nitrite based on the analyte-induced photoluminescence quenching... | 25,154,909 | [
-0.327159,
0.3642677,
-0.2157318,
-0.1652284,
0.229488,
-0.03147329,
-0.719759,
-0.1148061,
0.1534055,
0.006130632,
-0.2035138,
0.0156445,
0.2161837,
-0.2858925,
-0.6768999,
-0.07985394,
-0.5036913,
0.3245997,
-0.1327305,
-0.1209634,
0.3550502,
-0.2365295,
-0.1455412,
0... |
[Surgical treatment of chronic thromboembolic pulmonary hypertension]. | Chronic thromboembolic pulmonary hypertension is a rare but underdiagnosed disease. The development of imaging played a crucial role for the screening and the decision of operability over the past few years. Indeed, chronic thromboembolic pulmonary hypertension is the only type of pulmonary hypertension with a potentia... | 25,154,908 | [
0.09027825,
0.09808787,
-0.1131037,
-0.04766493,
-0.06571928,
-0.3067209,
-0.08190625,
0.05977286,
0.1019679,
-0.00381108,
0.1347734,
0.1261146,
-0.1282278,
-0.05282032,
-0.3291988,
-0.4400359,
-0.05563656,
0.2270035,
0.5000187,
0.3210046,
0.2145973,
0.4787216,
-0.394052,... |
Genetic strategies to understand physiological pathways regulating body weight. | Body weight is a highly heritable trait across species. In humans, genetic variation plays a major role in determining the inter-individual differences in susceptibility or resistance to environmental factors which influence energy intake and expenditure. In this review, I discuss how genetic studies have contributed t... | 25,154,910 | [
0.007645857,
-0.3142593,
-0.0640107,
-0.3660711,
-0.00969218,
-0.3550919,
-0.1159443,
-0.1287043,
0.1581098,
0.01916653,
0.2220948,
-0.0666003,
0.1147173,
-0.236176,
-0.5203122,
-0.1622306,
-0.3038065,
-0.06094484,
-0.0839714,
0.08971791,
-0.2381115,
0.1793185,
-0.2631972... |
Impact of alkaline-hydrolyzed biosolids (Lystek) addition on the anaerobic digestibility of TWAS in lab--and full-scale anaerobic digesters. | The effect of different Lystek biosolids doses on the anaerobic digestability of thickened waste activated sludge (TWAS) was evaluated in a lab- and full-scale anaerobic digester. The overall findings of this study emphasize the beneficial impact of Lystek addition to the lab- and full-scale anaerobic digesters in term... | 25,154,917 | [
0.1043444,
0.05159661,
-0.1268648,
0.04025029,
-0.2867026,
-0.1119556,
0.06625668,
-0.08940816,
0.2299407,
-0.2487809,
-0.05835128,
-0.01551717,
-0.1006699,
0.1085634,
-0.6288761,
0.07855529,
-0.4823729,
0.1309958,
0.2202986,
0.08650009,
0.03865565,
0.6258293,
-0.1654759,... |
Cationic amphipathic D-enantiomeric antimicrobial peptides with in vitro and ex vivo activity against drug-resistant Mycobacterium tuberculosis. | Tuberculosis (TB) is the leading cause of bacterial death worldwide. Due to the emergence of multi-drug resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB), and the persistence of latent infections, a safe and effective TB therapy is highly sought after. Antimicrobial peptides (AMPs) have therapeutic poten... | 25,154,927 | [
-0.05318834,
-0.1207046,
-0.007546258,
0.1764356,
0.09119198,
-0.06835588,
-0.3588668,
0.457349,
0.2749474,
-0.270464,
-0.01508902,
0.09508757,
-0.009580655,
0.5373421,
-0.4262004,
0.02952653,
-0.7474058,
-0.09891656,
0.01422177,
-0.189588,
0.06920198,
0.2344463,
-0.06784... |
The evaluation of family functioning by the family assessment device: a systematic review of studies in adult clinical populations. | A large body of research, documenting the impact of a family's functioning on health outcomes, highlights the importance of introducing the evaluation of patients' family dynamics into clinical judgment. The Family Assessment Device (FAD) is a self-report questionnaire designed to assess specific dimensions of family f... | 25,154,959 | [
-0.1196265,
0.1658274,
-0.04909495,
-0.2172544,
0.07013261,
-0.2765369,
0.02462265,
-0.07566731,
0.02655043,
-0.2703136,
-0.01287719,
0.03532702,
0.04690603,
-0.153567,
-0.6504372,
-0.09025034,
-0.2666065,
0.1629178,
-0.4092744,
0.3989086,
-0.2319088,
0.03933039,
-0.03997... |
A 2DRF pulse sequence for bolus tracking in hyperpolarized 13C imaging. | A novel application of two-dimensional (2D) spatially selective radiofrequency (2DRF) excitation pulses in hyperpolarized 13C imaging is proposed for monitoring the bolus injection with highly efficient sampling of the initially polarized substrate, thus leaving more polarization available for detection of the subseque... | 25,154,961 | [
-0.06461117,
-0.0004858054,
-0.4561318,
-0.04194341,
0.1643789,
-0.6680413,
0.1552196,
0.1106869,
-0.191724,
0.1500349,
-0.1870822,
-0.1113485,
0.4688909,
-0.009676477,
-0.4152727,
-0.1306548,
-0.30564,
-0.2534384,
-0.3468466,
0.01347558,
0.0474488,
0.07301363,
-0.0105629... |
[Clinical characteristics and efficiency of interventional therapy for coronary artery involvement in Takayasu's arteritis]. | To explore the clinical characteristics and efficacies of interventional therapy for coronary artery involvement in Takayasu's arteritis (TA). A total of 98 consecutive hospitalized TA patients with more than 50% diameter reduction of coronary artery by angiography were retrospectively analyzed from 2000 to 2013 at Pek... | 25,154,992 | [
0.03299071,
0.2400286,
-0.06778077,
0.0178788,
-0.07456385,
-0.06100898,
0.1830742,
0.2334857,
0.237257,
-0.07116804,
-0.08416318,
-0.07764465,
0.08903526,
-0.08422391,
-0.1137239,
-0.09495591,
-0.1910605,
0.4358416,
0.4316095,
0.1954377,
-0.04262801,
0.1265095,
-0.064379... |
A rare cause of gastro-intestinal hemorrhage in a patient with a Roux-en-Y gastric bypass. | This case illustrates a rare cause of gastro-intestinal bleeding following bariatric surgery. Though it is essential to rule out common causes of variceal formation accompanied by intermittent, profuse bleeding, there should be a high degree of suspicion of this rare etiology in patients who have previously undergone a... | 25,155,016 | [
-0.08658915,
-0.15903,
-0.1599707,
-0.234913,
-0.005879389,
-0.1945987,
-0.339164,
-0.1327945,
-0.1357282,
-0.05275787,
0.3165501,
0.1855936,
-0.08803046,
-0.2791982,
-0.3253981,
0.1286876,
-0.1173539,
0.02293246,
0.2891157,
-0.0730518,
-0.04920265,
0.1905949,
-0.09488972... |
Expression of p8 in Human Oral Squamous Cell Carcinoma. | The present study investigated the expression of p8, a transcription factor upregulated in some human cancers, in oral squamous cell carcinomas (OSCCs). Immunohistochemical analysis of p8 expression was carried out on 20 archived surgical specimens of human OSCCs, and expression correlated with clinical outcome paramet... | 25,155,047 | [
0.1529262,
-0.2831819,
-0.2645058,
-0.4177302,
-0.1832571,
-0.2999878,
-0.05704489,
0.05596637,
-0.1627031,
-0.004686029,
0.09313273,
0.1055011,
0.07258876,
-0.4732723,
-0.3356573,
-0.2568485,
-0.1701037,
-0.0360509,
-0.06679982,
0.3105214,
0.3371517,
0.2079534,
-0.049034... |
Retention behavior of alkylated polycyclic aromatic sulfur heterocycles on immobilized ionic liquid stationary phases. | Polycyclic aromatic sulfur heterocycles (PASH) are prevalent components of fossil fuel-based pollutants, and their accurate analysis is of critical importance in risk assessment and hazardous waste site remediation. PASH, however, have a wide range of volatilities and polarities and, as such, often coelute with one ano... | 25,155,062 | [
-0.2929814,
0.1939879,
0.01295361,
-0.1748343,
0.2527866,
0.1831269,
-0.4207662,
0.031169,
-0.174834,
-0.06417817,
-0.2823545,
-0.2095922,
-0.08997992,
0.1884177,
-0.03324096,
-0.07182861,
-0.5056443,
0.5219429,
0.187468,
0.2524471,
0.03431499,
0.3388556,
-0.1685968,
-0... |
Depletion of foxp3(+) T cells abrogates tolerance of skin and heart allografts in murine mixed chimeras without the loss of mixed chimerism. | The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+) ) maintain skin and heart allograft tolerance in mixed hematopoietic chimeric mice. Transient depletion of ... | 25,155,089 | [
0.001681973,
-0.2446941,
-0.106649,
-0.1045704,
0.3402751,
-0.2787078,
0.01414816,
0.4034035,
0.03559385,
-0.05978879,
0.1206406,
0.01239464,
0.2840793,
-0.1141669,
-0.4852123,
-0.3442314,
-0.2628669,
-0.1929744,
-0.1920496,
0.04933373,
-0.08541701,
0.1804371,
0.01582023,... |
Opioid use and depression in chronic pelvic pain. | Opioid pain medications and antidepressants are commonly prescribed to patients for chronic non-cancer pain. However, little evidence exists for their effectiveness in most pain states, including chronic pelvic pain. Whenever possible, initiation of opioid pain medications in chronic non-cancer pain should be avoided. ... | 25,155,127 | [
-0.2892417,
0.1792727,
0.08576382,
0.03076714,
-0.08208234,
-0.1033845,
-0.1398796,
0.03161364,
0.08580936,
-0.2063215,
0.1036372,
0.162529,
-0.04498955,
0.08319966,
-0.1659974,
-0.01854063,
-0.1826458,
0.4534122,
0.2624093,
-0.3062033,
-0.4624915,
0.04621235,
-0.1333341,... |
Attitudes of physicians and pharmacists towards International Non-proprietary Name prescribing in Belgium. | International Non-proprietary Name (INN) prescribing is the use of the name of the active ingredient(s) instead of the brand name for prescribing. In Belgium, INN prescribing began in 2005 and a major policy change occurred in 2012. The aim was to explore the opinions of Dutch-speaking general practitioners (GPs) and p... | 25,155,133 | [
-0.249754,
0.4629788,
0.2455892,
0.3485159,
0.2166947,
-0.05253302,
0.1861014,
-0.06487976,
0.1203788,
-0.1325789,
-0.1459778,
0.07932445,
-0.03794849,
-0.02080082,
-0.2082542,
0.03510992,
-0.7239035,
0.3126295,
-0.1848105,
0.1003813,
0.2462599,
-0.06079414,
0.06725741,
... |
Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity. | Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently coexist and are always present in patients with aspirin exacerbated respiratory disease (AERD). Although the pathogenic mechanisms of this condition are still unknown, AERD may be due, at least in part, to an imbalance in eicosanoid metabolism (inc... | 25,155,136 | [
-0.1236391,
-0.2826978,
0.04812441,
-0.1789384,
-0.1195213,
-0.02819706,
0.04468662,
0.1590444,
0.4052082,
0.03138317,
0.0949318,
0.03611998,
-0.2269359,
-0.3377976,
-0.2617539,
-0.01747174,
-0.2291255,
0.03683177,
0.1532367,
0.07434496,
-0.2198131,
0.270775,
-0.3566922,
... |
Whole blood metal ion measurement reproducibility between different laboratories. | Monitoring patients' metal ion blood concentrations can be useful in cases of problematic metal on metal hip implants. Our objective was to evaluate the reproducibility of metal ion level values measured by two different laboratories. Whole blood samples were collected in 46 patients with metal on metal hip arthroplast... | 25,155,139 | [
-0.2977524,
0.03046993,
-0.16938,
-0.1282555,
-0.2437366,
-0.2296337,
-0.2344968,
0.4029018,
-0.3271745,
0.06393088,
0.3138738,
0.4809569,
0.1570958,
-0.3107663,
-0.3871675,
-0.2372084,
-0.009339506,
0.1902241,
-0.02273908,
0.1222613,
0.2731391,
-0.003395937,
-0.1350821,
... |
PKCδ is required for porcine reproductive and respiratory syndrome virus replication. | Protein kinase C (PKC) that transduces signals to modulate a wide range of cellular functions has been shown to regulate a number of viral infections. Herein, we showed that inhibition of PKC with the PKC inhibitor GF109203X significantly impaired porcine reproductive and respiratory syndrome virus (PRRSV) replication.... | 25,155,198 | [
0.0201057,
-0.1174879,
0.2456799,
-0.1363926,
0.2454704,
0.1632368,
0.1415403,
0.1218174,
0.09869118,
0.03885742,
0.1435644,
-0.05949947,
-0.3322059,
0.1730171,
0.03791854,
0.09151235,
-0.4516322,
-0.09353866,
0.1423803,
-0.1837523,
0.08254108,
-0.02418717,
-0.2945782,
... |
Is rotator cuff repair appropriate in patients older than 60 years of age? prospective, randomised trial in 103 patients with a mean four-year follow-up. | The objective of this randomised trial was to compare surgical rotator cuff repair to simple decompression by acromioplasty and biceps tenotomy in patients older than 60 years of age with a mean follow-up of 4 years. Tendon repair produces better functional outcomes than simple decompression and prevents progression to... | 25,155,203 | [
0.07956987,
0.2811903,
0.08284122,
-0.4692975,
-0.2769342,
-0.2357209,
-0.212708,
0.227379,
0.05976903,
0.002277172,
0.1934278,
-0.3567346,
-0.124002,
-0.3260504,
-0.1522022,
-0.1497758,
-0.2755294,
0.2002226,
-0.1325468,
-0.004485417,
0.002772933,
0.02170442,
0.2928727,
... |
The surgical management of gallbladder cancer. | Among biliary tract cancers, gallbladder cancer (GBC) is a potentially lethal malignancy with abysmal long-term survival. Surgery is central to the management of GBC, and presently, provides the only ray of hope for long-term survival. Radical cholecystectomy, which includes cholecystectomy with a limited hepatic resec... | 25,155,211 | [
0.1358013,
-0.06388528,
-0.2940308,
-0.4927766,
-0.1786001,
-0.3106802,
-0.1323584,
-0.153423,
-0.01434694,
0.1300806,
-0.007864242,
0.1648473,
-0.0463715,
0.283174,
-0.09695148,
-0.5279695,
-0.4233792,
0.2875947,
0.365502,
-0.274233,
-0.02986107,
0.2491029,
-0.06861935,
... |
The effect of magnetic resonance imaging noise on cochlear function in dogs. | Noise produced by magnetic resonance imaging (MRI) scanners (which can peak at a sound pressure level of 131 dB) has been shown to cause noise-induced cochlear dysfunction in people. The aim of this study was to investigate whether noise produced during MRI had a deleterious effect on cochlear function in dogs, using d... | 25,155,216 | [
-0.03656948,
0.06817697,
0.2506885,
-0.119054,
-0.09566984,
-0.4699498,
0.08534861,
-0.3184679,
-0.07371841,
-0.3156545,
0.006198635,
0.1526848,
-0.1692961,
-0.5523589,
-0.2351119,
-0.1820275,
-0.3095618,
0.3267469,
-0.2073696,
-0.3586224,
-0.3498353,
0.1353694,
-0.103856... |
Prevalence of canine influenza virus A (H3N8) in dogs in Germany. | The aim of this study was to investigate the prevalence of CIV H3N8 in dogs in Germany. Blood samples from 272 clinically healthy dogs and 35 dogs with acute respiratory signs were screened for antibodies against influenza virus by ELISA and haemagglutination inhibition (HI) assay; positive samples were further tested ... | 25,155,218 | [
-0.01860303,
0.06238222,
-0.07586342,
-0.1709838,
0.1479961,
0.03948266,
-0.06369252,
0.2618443,
-0.2311046,
-0.194068,
0.2764166,
0.08486278,
0.2657769,
-0.6132131,
-0.1449212,
-0.434074,
0.05268529,
0.4269699,
-0.161699,
0.1423317,
0.1335233,
0.04269202,
-0.4066861,
-... |
Bone-prosthesis composite with rotating hinged-knee prosthesis in limb salvage surgery for high-grade sarcoma around the knee. | Bone prosthesis composite (BPC) had been widely-used in reconstruction after wide excision of malignant tumors around the knee. However, implant selection for BPC remains a dilemma. Forty-one patients with high-grade malignant bone tumors around the knee who underwent excision and reconstruction with BPC and rotating h... | 25,155,237 | [
-0.06248236,
0.2234337,
-0.09265381,
0.3170072,
-0.2166128,
-0.06536538,
0.08374187,
0.3504847,
-0.1259044,
0.27928,
0.08701549,
-0.4490373,
-0.2035478,
0.3928584,
-0.05073431,
-0.4855511,
-0.02267917,
0.1225626,
0.1581563,
-0.08488914,
0.1295852,
0.1022419,
0.3832054,
... |
Alteration of hindfoot alignment after total knee arthroplasty using a novel hindfoot alignment view. | This study examined the coronal alignment of the hindfoot in varus osteoarthritis of the knee before and after total knee arthroplasty (TKA) in 100 legs using a novel imaging method. We categorized the preoperative hindfoot alignment into varus (30 legs) and valgus (70 legs) groups; imaging of the hindfoot was conducte... | 25,155,238 | [
-0.02488322,
0.2217018,
-0.02840269,
-0.2211176,
0.07882836,
-0.09157506,
0.2023489,
0.0775818,
-0.08262426,
-0.1722561,
0.08884291,
0.1506439,
-0.2060411,
-0.07649318,
0.03317395,
-0.3015121,
-0.0343157,
0.4765455,
-0.1083889,
-0.1996875,
-0.4776505,
0.1392932,
0.0110849... |
The disproportionation of [Ni(tacn)]2+ in Ni2+ and [Ni(tacn)2]2+ crystallographically demonstrated (tacn = 1,4,7-triazacyclononane). | From an EtOH/H2O solution, 0.3 M each of Ni(2+) and cyclic triamine tacn (2; tacn = 1,4,7-triazacyclononane), after 10 min refluxing and cooling at room temperature, copious and comparable amounts of blue crystals (containing the complex [Ni(tacn)(H2O)3](2+)) and pink crystals (containing in the same cell both [Ni(H2O)... | 25,155,239 | [
-0.183461,
-0.01279588,
-0.4406674,
-0.04498863,
0.1016819,
0.06219769,
-0.3863617,
0.1792239,
0.1028498,
0.07294656,
-0.05855311,
-0.03196584,
0.06733093,
-0.08403471,
-0.5357897,
-0.290616,
-0.338853,
0.17106,
0.04471509,
0.356233,
0.3680367,
0.2614557,
-0.1745303,
0.... |
Linking neocortical, cognitive, and genetic variability in autism with alterations of brain plasticity: the Trigger-Threshold-Target model. | The phenotype of autism involves heterogeneous adaptive traits (strengths vs. disabilities), different domains of alterations (social vs. non-social), and various associated genetic conditions (syndromic vs. nonsyndromic autism). Three observations suggest that alterations in experience-dependent plasticity are an etio... | 25,155,242 | [
-0.02905383,
-0.03583588,
0.2165913,
-0.1696242,
0.05462138,
-0.2291715,
-0.008811818,
-0.1494309,
0.1875248,
0.2605215,
-0.076872,
0.3791574,
-0.1420813,
-0.4344122,
-0.3782399,
0.03661492,
-0.6637215,
-0.1984407,
-0.02569699,
-0.1104456,
-0.2877223,
0.3680119,
-0.218365... |
Nonalcoholic fatty liver disease (NAFLD) in the Veterans Administration population: development and validation of an algorithm for NAFLD using automated data. | In practice, nonalcoholic fatty liver disease (NAFLD) is diagnosed based on elevated liver enzymes and confirmatory liver biopsy or abdominal imaging. Neither method is feasible in identifying individuals with NAFLD in a large-scale healthcare system. To develop and validate an algorithm to identify patients with NAFLD... | 25,155,259 | [
-0.1804219,
-0.02026993,
-0.2338581,
0.04176508,
0.1688116,
-0.0805172,
-0.1068398,
0.1864638,
0.1566977,
-0.002385412,
0.07086379,
-0.2129397,
0.22314,
0.174646,
-0.2306023,
-0.2156825,
-0.1166887,
0.409002,
0.1780249,
-0.1508758,
-0.6174461,
-0.06164507,
-0.4555501,
0... |
Association of JARID2 polymorphisms with non-syndromic orofacial clefts in northern Chinese Han population. | Non-syndromic orofacial clefts (NSOC) are the most common human craniofacial malformation in all worldwide populations. Recently, the jumoji AT-rich interaction domain 2 (JARID2) had been reported to be a novel candidate gene for non-syndromic cleft lip with or without cleft palate (CL/P). The SNPs rs2076056, rs2237138... | 25,155,265 | [
0.2234155,
0.19318,
0.3138497,
-0.204717,
-0.02008316,
0.04851126,
-0.3515269,
0.1282782,
0.3284084,
-0.162948,
0.3638377,
0.4858035,
-0.1634971,
0.2458761,
-0.08552016,
-0.2867055,
-0.08900713,
-0.1878077,
0.2329607,
-0.1308557,
-0.1372108,
0.2858306,
-0.03520035,
0.22... |
A new paper-based platform technology for point-of-care diagnostics. | Currently, the Lateral flow Immunoassays (LFIAs) are not able to perform complex multi-step immunodetection tests because of their inability to introduce multiple reagents in a controlled manner to the detection area autonomously. In this research, a point-of-care (POC) paper-based lateral flow immunosensor was develop... | 25,155,271 | [
-0.1694011,
-0.08057971,
-0.1429526,
0.03300877,
-0.02063372,
-0.005258393,
-0.2749178,
0.5281112,
-0.1935593,
0.1482036,
0.09235343,
0.1226044,
-0.22053,
-0.04658024,
-0.1925471,
0.03503753,
-0.4756656,
-0.08531118,
-0.1856599,
0.1262944,
0.2539332,
0.08987721,
-0.357522... |
Genomic characterization of the LEED..PEEDs, a gene family unique to the medicago lineage. | The LEED..PEED (LP) gene family in Medicago truncatula (A17) is composed of 13 genes coding small putatively secreted peptides with one to two conserved domains of negatively charged residues. This family is not present in the genomes of Glycine max, Lotus japonicus, or the IRLC species Cicer arietinum. LP genes were a... | 25,155,275 | [
-0.2708699,
-0.0519857,
0.3634854,
0.182569,
-0.0780923,
-0.1278608,
-0.1197035,
-0.119229,
0.2933179,
-0.2457931,
-0.2162873,
0.158997,
-0.02802827,
0.09121013,
-0.2925259,
0.01860342,
-0.5507035,
-0.2889575,
-0.05451525,
-0.2294353,
-0.01033065,
0.3257242,
-0.1856473,
... |
Venous thromboembolism risk factors in Chinese non-small cell lung cancer patients. | Certain clinicopathological factors contribute to the development of venous thromboembolism (VTE) in lung cancer. The aim of the current study was to assess the incidence of and the potential risk factors associated with the development of VTE in Chinese lung cancer patients. Patients with lung cancer in our center wer... | 25,155,313 | [
0.1594407,
0.152795,
-0.1650732,
-0.3286542,
-0.3601329,
-0.105465,
0.1531956,
0.06666383,
-0.4891841,
0.0167811,
0.05536362,
0.4931104,
-0.04638211,
-0.2125968,
0.3037857,
-0.2880438,
0.02871037,
0.1209128,
0.4625773,
0.1705738,
0.2112196,
0.1649828,
-0.2475437,
0.2216... |
In vitro investigation on extensively destroyed vital teeth: is fracture force a limiting factor for direct restoration? | To evaluate the in vitro fracture load of extensively damaged vital teeth after either direct or indirect restauration, severe tooth substance loss was simulated for 96 molars. Subsequently, two cavities were prepared with little (design 1) or more substantial (design 2) residual tooth support. All molars were provided... | 25,155,353 | [
-0.2024229,
0.3262768,
-0.1206603,
0.15929,
-0.05297782,
-0.1268599,
0.1986329,
0.2136367,
-0.005813219,
0.08289249,
-0.002528863,
0.2638355,
0.102095,
0.01876676,
0.09164707,
-0.04815589,
0.01051432,
-0.135649,
-0.3607515,
-0.066664,
0.3590767,
0.3251153,
0.01885625,
0... |
Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. | The current therapy for glioblastoma multiforme (GBM), the most aggressive and common primary brain tumor of adults, involves surgery and a combined radiochemotherapy that controls tumor progression only for a limited time window. Therefore, the identification of new molecular targets is highly necessary. Inhibition of... | 25,155,357 | [
-0.2077743,
-0.04428392,
-0.09392095,
-0.5519746,
0.2220106,
-0.06664105,
0.08100966,
0.1111878,
-0.00695321,
0.123669,
0.07820961,
-0.002996406,
-0.2547346,
-0.4291603,
-0.09771935,
0.02494478,
-0.008181284,
0.3434815,
0.02950298,
0.2253266,
0.3781615,
0.4558838,
0.12070... |
Serous neoplasms of the pancreas share many, but not all aspects of their microvascular and angiogenic profile with low-grade clear cell renal cell carcinomas. | Similarly to clear cell renal cell carcinomas (CCRCC), serous neoplasms (SN) of the pancreas frequently show inactivation of VHL gene, clear cell histology and abundant microvasculature. Data on the microvascular and angiogenic profile of SN are scarce. Aiming to examine further the striking resemblance of clear cell e... | 25,155,377 | [
0.0482188,
-0.05438546,
0.0253519,
0.1007178,
-0.2126008,
-0.2447295,
0.2597913,
-0.214941,
0.1164076,
0.4197955,
0.03630159,
-0.03601122,
-0.5296558,
-0.3631659,
-0.6379291,
-0.143856,
-0.3695123,
0.1661482,
0.101616,
0.2509999,
0.1780799,
0.3518578,
-0.1464613,
0.2756... |
Comparison of three ECG criteria for athlete pre-participation screening. | Controversy regarding adding the ECG to the evaluation of young athletes centers on the implications of false positives. Several guidelines have been published with recommendations for criteria to distinguish between ECG manifestations of training and markers of risk for cardiovascular (CV) sudden death. With an athlet... | 25,155,389 | [
-0.498976,
0.3207745,
-0.1667866,
-0.4433638,
0.00455366,
-0.3177784,
-0.1888513,
0.005144818,
-0.004531006,
0.05309646,
0.05953322,
0.5468177,
-0.116652,
-0.4264719,
-0.3097086,
-0.3848487,
-0.4538409,
0.145553,
0.03827271,
-0.03675779,
0.07038224,
0.1474263,
-0.2350783,... |
Improved survival in osteosarcoma patients with atypical low vascularization. | Osteosarcoma is considered a highly vascularized bone tumor with early metastatic dissemination through intratumoral blood vessels mostly into the lung. Novel targets for therapy such as tumor vascularization are highly warranted since little progress has been achieved in the last 30 years. However, proof of relevance ... | 25,155,396 | [
0.09428243,
0.2842526,
-0.2639468,
-0.3218458,
-0.2964502,
-0.253359,
-0.01375809,
0.4223153,
0.01540366,
-0.0641751,
0.2298947,
0.1617813,
0.004917448,
-0.555089,
-0.6914616,
0.1036087,
-0.2612002,
0.09742897,
0.02544759,
0.3261315,
0.3396384,
0.3293315,
-0.2673697,
0.... |
The spectrum of β-thalassemia mutations in Hatay, Turkey: reporting three new mutations. | β-Thalassemia (β-thal) is an important health problem in Hatay, Southern Turkey, because of its high carrier frequency and the frequency of consanguinity. The aim of this study was to reveal the spectrum of β-thal mutations and to provide a foundation for prenatal genetic testing that will be a part of an effective pre... | 25,155,404 | [
0.04826167,
0.07144073,
-0.06520236,
-0.01318288,
0.3607924,
-0.07756495,
-0.01007341,
-0.09002338,
0.09842602,
0.036039,
0.2875702,
0.3116019,
-0.1776896,
-0.003666154,
0.108261,
-0.4352638,
-0.3200494,
-0.0638771,
0.1373834,
-0.03087272,
0.3607264,
0.4886723,
-0.1392943... |
Do the intestinal microbiotas differ between paddlefish (Polyodon spathala) and bighead carp (Aristichthys nobilis) reared in the same pond? | A study was conducted to compare the intestinal microbial compositions of two fish species with similar feeding strategy; paddlefish (Polyodon spathala) and bighead carp (Aristichthys nobilis) reared in the same pond. Age-0 paddlefish and bighead carp with mean average body lengths of 43·39 ± 2·78 and 19·33 ± 3·68 cm, ... | 25,155,438 | [
0.0940569,
0.4475466,
0.2956112,
0.2753949,
0.4416314,
-0.2072975,
-0.132988,
0.5263161,
-0.1660659,
-0.01811649,
0.1388522,
-0.4082374,
-0.1030732,
-0.3105994,
-0.2438942,
-0.2177513,
-0.6121999,
0.2072345,
-0.1152385,
0.3085099,
-0.004816221,
0.5019628,
-0.1812309,
-0... |
Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease. | Fabry disease is an X-linked recessive disorder caused by the loss of function of the lysosomal enzyme α-Galactosidase-A. Although two enzyme replacement therapies (ERTs) are commercially available, they may not effectively reverse some of the Fabry pathology. PRX-102 is a novel enzyme for the therapy of Fabry disease ... | 25,155,442 | [
0.2213789,
-0.2633276,
-0.5668318,
0.1163313,
0.3595193,
-0.06820036,
-0.03271134,
0.2300552,
-0.1033768,
-0.02643308,
-0.05633183,
-0.1119838,
0.1908596,
-0.05476205,
-0.4033329,
0.06207934,
-0.2822784,
-0.2940135,
-0.4046471,
0.4023326,
0.04675625,
0.9608451,
-0.3585169... |
Safety and efficacy of thrombopoietin-receptor agonists in myelodysplastic syndromes: a systematic review and meta-analysis of randomized controlled trials. | Thrombocytopenia is common (40-65%) and potentially serious in myelodysplastic syndromes (MDS). A systematic review was conducted to determine the safety and efficacy of adding a thrombopoietin-receptor (THPO-R) agonist to standard MDS treatment. MEDLINE, EMBASE and CENTRAL databases were searched. We included randomiz... | 25,155,450 | [
0.2329056,
-0.2271216,
-0.3001639,
-0.4679301,
0.1237042,
-0.212203,
0.2877738,
0.117631,
-0.2592779,
-0.09057661,
-0.1444267,
0.04633294,
-0.04642772,
0.04591863,
-0.03150624,
-0.3265545,
-0.3080685,
0.1328093,
-0.1945341,
0.1272082,
0.1056362,
0.2113186,
-0.009797127,
... |
Evaluating tumor metastatic potential by imaging intratumoral acidosis via pH-activatable near-infrared fluorescent probe. | Metastasis accounts for the vast majority of cancer deaths. To minimize metastasis-associated mortality, it is crucially important to evaluate the metastatic potential (M.P.), that is, defined as a tendency of a primary tumor to colonize a distant organ. Dysregulated pH in solid tumors, especially the acidification of ... | 25,155,456 | [
0.006923435,
-0.1234463,
-0.07291516,
0.1223215,
-0.250277,
-0.1286786,
0.09561937,
0.4413798,
-0.04618182,
-0.2282426,
-0.1942092,
0.1954906,
-0.07417129,
-0.1566155,
-0.3373795,
-0.002990095,
-0.6400613,
0.2328247,
0.3060394,
0.2941964,
0.2809042,
0.3133398,
-0.130822,
... |
The phylogenetic position of Kofoidia loriculata (Parabasalia) and its implications for the evolution of the Cristamonadea. | Kofoidia loriculata is a parabasalid symbiont inhabiting the hindgut of the lower termite Paraneotermes simplicicornis. It was initially described as a lophomonad due to its apical tuft of multiple flagella that disintegrate during cell division, but its phylogenetic relationships have not been investigated using molec... | 25,155,455 | [
0.2850047,
-0.3063115,
-0.08705987,
0.188164,
0.02224816,
-0.006729408,
-0.01390416,
0.02060308,
0.1410835,
-0.2230361,
-0.000553459,
-0.2278487,
0.01688408,
0.05189377,
-0.3397553,
-0.1166569,
-0.6199055,
-0.04060276,
0.1907696,
-0.09744259,
0.04586703,
0.2485403,
-0.035... |
A surface with a biomimetic micropattern reduces colonization of Mycobacterium abscessus. | Nontuberculous mycobacteria (NTM) are ubiquitous organisms found in soil, water, and biofilms. Engineered surface topography has been proposed as a method to reduce microbial biofilm formation. The Sharklet(®) micropattern silicone surface has been shown to reduce biofilm formation of pyogenic bacteria. We hypothesized... | 25,155,501 | [
0.1718239,
0.1573371,
-0.2438145,
0.3028034,
-0.4092079,
-0.1484086,
-0.5321558,
-0.2603332,
0.1732278,
-0.1412916,
-0.1958948,
0.2047861,
-0.2034596,
0.1705817,
-0.1666267,
0.1373689,
-0.3954212,
0.2043623,
-0.283123,
-0.2302957,
0.1281296,
0.1997597,
0.1668553,
-0.228... |
Actin is required for IFT regulation in Chlamydomonas reinhardtii. | Assembly of cilia and flagella requires intraflagellar transport (IFT), a highly regulated kinesin-based transport system that moves cargo from the basal body to the tip of flagella [1]. The recruitment of IFT components to basal bodies is a function of flagellar length, with increased recruitment in rapidly growing sh... | 25,155,506 | [
-0.1069055,
0.07558623,
-0.08205827,
0.05523487,
0.1635665,
-0.001255826,
0.05921726,
0.2917298,
0.03902605,
0.05210005,
0.1777213,
0.2002604,
-0.2275073,
0.154382,
0.1563912,
0.09840524,
-0.5510442,
0.1754028,
-0.2774177,
-0.04909871,
0.2413913,
0.1352049,
-0.01643468,
... |
Decoupling physical from biological processes to assess the impact of viruses on a mesoscale algal bloom. | Phytoplankton blooms are ephemeral events of exceptionally high primary productivity that regulate the flux of carbon across marine food webs [1-3]. Quantification of bloom turnover [4] is limited by a fundamental difficulty to decouple between physical and biological processes as observed by ocean color satellite data... | 25,155,511 | [
-0.1964919,
0.2323437,
-0.09486298,
0.06985793,
-0.2756773,
-0.1584331,
-0.05019978,
0.2667456,
0.12517,
-0.1523491,
-0.2237442,
-0.02893397,
-0.1571507,
0.07892026,
-0.2723144,
-0.03816003,
-0.3922367,
0.402429,
0.1642193,
0.1390898,
0.372025,
0.3239705,
-0.1624382,
-0... |
Arabidopsis inositol pentakisphosphate 2-kinase, AtIPK1, is required for growth and modulates phosphate homeostasis at the transcriptional level. | Inositol hexakisphosphate (IP6 ) provides a phosphorous reservoir in plant seeds; in addition, along with its biosynthesis intermediates and derivatives, IP6 also plays important roles in diverse developmental and physiological processes. Disruption of the Arabidopsis inositol pentakisphosphate 2-kinase coding gene AtI... | 25,155,524 | [
0.2411526,
-0.1442701,
0.01593854,
-0.1496029,
-0.02648728,
0.1598857,
0.1305475,
-0.002243661,
-0.03093622,
-0.1438751,
0.2049855,
0.02272381,
-0.6158348,
0.3659465,
-0.4128961,
0.2821144,
-0.3284962,
0.3186394,
-0.04645669,
-0.3871714,
0.2126641,
0.4416499,
-0.06964159,... |
Cancer survivors' uptake and adherence in diet and exercise intervention trials: an integrative data analysis. | The health benefits of diet and exercise interventions for cancer survivors are well documented. However, little is known regarding demographic and medical predictors of survivors' willingness to participate in diet and exercise intervention trials, study enrollment, intervention adherence, and study completion. To ass... | 25,155,573 | [
-0.2601749,
0.1022117,
-0.3071843,
-0.1987967,
-0.1629922,
-0.3734289,
-0.08121392,
0.1652617,
0.2821995,
-0.1008279,
0.00831612,
0.01457307,
-0.224077,
-0.6395265,
-0.04440646,
-0.1770866,
-0.1547172,
0.3390905,
-0.1547558,
0.1415528,
-0.1479524,
0.1039702,
-0.1949543,
... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.