title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
|---|---|---|---|
Orbital complications of rhinosinusitis. | Suppurative extension of rhinosinusitis to the orbit is a complication that often results from delay in diagnosis and, or inadequate treatment. These complications may range from preseptal cellulitis, orbital cellulitis, orbital abscesses, and subperiosteal abscesses to intracranial extension with a threat to both visi... | 25,161,430 | [
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ASSESSMENT OF TRAINING ON MEASLES CASE-BASED SURVEILLANCE FOR DISEASE SURVEILLANCE AND NOTIFICATION OFFICERS (DSNOs) IN OSUN STATE. | Poor knowledge among Disease Surveillance and Notification Officers (DSNOs) as a result of high staff turnover has been identified as a major reason for sub-optimal surveillance performance in Osun State. Training aimed at strengthening the measles surveillance sub-system of the Integrated Disease Surveillance and Resp... | 25,161,463 | [
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Some ethical issues in the prenatal diagnosis of sickle cell anaemia. | Sickle cell anaemia (SCA) is the most common form of haemoglobinopathy in Nigeria affecting 1-3% of the population and it is associated with physical, psychosocial and emotional suffering. Prenatal diagnosis (PND) and genetic counseling are ways of preventing the spread of the disease; however these means of prevention... | 25,161,466 | [
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Routine antenatal syphilis screening in South west Nigeria- a questionable practice. | Untreated maternal syphilis is strongly associated with adverse birth outcomes, especially in women with high titre syphilis. The WHO recommends routine serological screening in pregnancy. Some workers have advised a reappraisal of this practice, having demonstrated low sero-prevalence in their antenatal population. In... | 25,161,469 | [
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The microbiological diagnosis of tuberculosis in a resource - limited setting: is Acid-fast bacilli microscopy alone sufficient? | The objective of this study is to audit the processes for the microbiological diagnosis of tuberculosis (TB) in our resource-limited setting. A total of 694 specimens were received from 333 patients. 129 (38.7%) of these patients were positive for TB. 78 (60.5%) were positive on AFB microscopy alone, 13 (10.0%) on cult... | 25,161,484 | [
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Psychosocial aspect of anterior tooth discoloration among adolescents in igbo-ora, southwestern Nigeria. | Aesthetic problems in adolescence can have a significant effect on their psychosocial development. Abnormalities in tooth color can lead to such problem especially if it affects anterior teeth. This study therefore assessed the effects of anterior tooth discoloration on the psychosocial well-being of adolescents with a... | 25,161,491 | [
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Abdominal pain in adult sickle cell disease patients: a nigerian experience. | Abdominal pain is a relatively frequent occurrence in sickle cell disease. The aetiology of abdominal pain in sickle cell disease is often difficult to diagnose clinically. Despite the frequent occurrence, diagnostic dilemma, and the need for an accurate, early diagnosis, abdominal pain in sickle cell disease has not b... | 25,161,492 | [
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Economic problems of youth with hiv/aids in ibadan, Nigeria. | HIV/AIDS has emerged as one of the major global public health problems and it also has substantial economic impact on individuals and their families. This paper describes the economic problems of youth with HIV in Ibadan, Nigeria. A cross-sectional survey of PLWHA attending two HIV/AIDS support groups in Ibadan and the... | 25,161,493 | [
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Crystal structures of (μ2-η(2),η(2)-4-hydroxybut-2-yn-1-yl 2-bromo-2-methylpropanoate-κ(4) C (2),C (3):C (2),C (3))bis[tricarbonylcobalt(II)](Co-Co) and [μ2-η(2),η(2)-but-2-yne-1,4-diyl bis(2-bromo-2-methyl-propanoate)-κ(4) C (2),C (3):C (2),C (3)]bis[tricarbonylcobalt(II)](Co-Co). | The title compounds, [Co2(C8H11BrO3)(CO)6], (1), and [Co2(C12H16Br2O4)(CO)6], (2), result from the replacement of two carbonyl ligands from dicobalt octa-carbonyl by the alkynes 4-hy-droxy-but-2-ynyl 2-bromo-2-methyl-propano-ate and but-2-yne-1,4-diyl bis-(2-bromo-2-methyl-propano-ate), respectively. Both mol-ecules ha... | 25,161,495 | [
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Thortveitite-type Tm2Si2O7. | Single crystals of dithulium disilicate, Tm2Si2O7, were obtained in flux synthesis experiments in the system SiO2-Tm2O3-LiF at ambient pressure. The compound belongs to the group of sorosilicates, i.e. it is based on [Si2O7]-units and crystallizes in the thortveitite (Sc2Si2O7) structure type. The Tm(3+) cation (site s... | 25,161,507 | [
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(η(4)-Cyclo-octa-tetra-ene)(η(8)-cyclo-octa-tetra-ene)iodido-tantalum(V). | The title complex, [Ta(η(4)-C8H8)(η(8)-C8H8)I], lies across a crystallographic mirror plane that includes the Ta(V) atom and the iodide ligand. One cyclo-octa-tetra-ene (cot) ring is η(4)-coordinating and is bis-ected by the mirror plane. The fold angle between the plane of the coordinating butadiene portion and the mi... | 25,161,515 | [
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Poly[[(μ4-benzene-1,3,5-tri-carboxyl-ato-κ(4) O (1):O (1'):O (2):O (3))bis-(2,2-bi-pyridine-κ(2) N,N')(μ2-hydroxido)dicopper(II)] trihydrate]. | In the title two-dimensional coordination polymer, {[Cu2(C9H3O6)(OH)(C10H8N2)2]·3H2O} n , each of the two independent Cu(II) atoms is coordinated by a bridging OH group, two O atoms from two benzene-1,3,5-tri-carboxyl-ate (L) ligands and two N atoms from a 2,2- bi-pyridine (bipy) ligand in a distorted square-pyramidal ... | 25,161,530 | [
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8-Chloro-4-oxo-4H-chromene-3-carbaldehyde. | In the title compound, C10H5ClO3, a chlorinated 3-formyl-chromone derivative, all atoms are essentially coplanar (r.m.s. deviation = 0.032 Å for the non-H atoms), with the largest deviation from the least-squares plane [0.0598 (14) Å] being for a pyran-ring C atom. In the crystal, mol-ecules are linked through stacking... | 25,161,540 | [
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Ethyl 2-[({[4-amino-5-cyano-6-(methyl-sulfan-yl)pyridin-2-yl]carbamo-yl}meth-yl)sulfan-yl]acetate monohydrate. | The title compound, C13H16N4O3S2·H2O, crystallizes in a 'folded' conformation with the ester group lying over the carbamoyl moiety, with one solvent water mol-ecule. The mol-ecular conformation is stabilized by an intra-molecular C-H⋯O hydrogen bond, and an N-H⋯O hydrogen-bonding inter-action involving the lattice wate... | 25,161,542 | [
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Methyl 5-methyl-1-(1H-pyrazol-3-yl)-1H-1,2,3-triazole-4-carboxyl-ate. | The asymmetric unit of the title compound, C8H9N5O2, contains two independent mol-ecules (A and B) in which the dihedral angles between the triazole and pyrazole rings are 4.80 (14) and 8.45 (16)°. In the crystal, mol-ecules are linked by N-H⋯N hydrogen bonds into supra-molecular independent A and B chains propagating ... | 25,161,549 | [
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5'-([1,1'-Biphen-yl]-4-yl)-1',1'',3''-tri-methyl-dispiro[indane-2,2'-pyrrolidine-4',5''-[1,3]diazin-ane]-1,3,2'',4'',6''-penta-one. | In the title compound, C30H25N3O5, the central five-membered heterocyclic ring adopts an envelope conformation, with the N atom as the flap. The dihedral angles between this central ring and the pendant indane ring system, the trione and benzene rings are 87.49 (5), 82.95 (10) and 72.42 (10)°, respectively. The dihedra... | 25,161,552 | [
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N-[(1-Benzoyl-piperidin-4-yl)meth-yl]benzamide. | In the title compound, C20H22N2O2, the piperidine ring adopts a chair conformation. The phenyl rings are inclined to one another by 80.1 (1)° and make dihedral angles of 46.1 (1) and 40.2 (1)° with the mean plane of the piperidine ring. In the crystal, pairs of N-H⋯O hydrogen bonds link the mol-ecules into inversion di... | 25,161,560 | [
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6-Bromo-N-(6-bromo-pyridin-2-yl)-N-[4-(2,3-di-hydro-thieno[3,4-b][1,4]dioxin-5-yl)phen-yl]pyridin-2-amine. | In the title mol-ecule, C22H15Br2N3O2S, the central benzene ring forms dihedral angles of 12.39 (17), 56.66 (17) and 74.71 (19)°, respectively, with the mean planes of the thio-phene and two pyridine rings. The dioxane ring is in a half-chair conformation. An intra-molecular C-H⋯O hydrogen forms an S(6) ring. The amine... | 25,161,578 | [
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5-Bromo-3-ethyl-sulfinyl-2-(4-methyl-phen-yl)-1-benzo-furan. | In the title compound, C17H15BrO2S, the dihedral angle between the plane of the benzo-furan ring system [r.m.s. deviation = 0.004 (3) Å] and that of the 4-methyl-phenyl ring is 0.9 (2)°. In the crystal, mol-ecules are linked by C-H⋯O, C-H⋯π and Br⋯π [3.636 (2) Å] inter-actions, and by π-π inter-actions between the 4-me... | 25,161,589 | [
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2,6-Di-amino-4-(4-chloro-phen-yl)-1-methyl-1,4-di-hydro-pyridine-3,5-dicarbo-nitrile. | In the title compound, C14H12ClN5, the di-hydro-pyridine ring adopts a shallow boat conformation. The dihedral angle between the plane of this ring and that of the chloro-benzene ring is 69.15 (15)°. In the crystal, mol-ecules are linked by N-H⋯N and N-H⋯Cl hydrogen bonds, generating (001) sheets. | 25,161,592 | [
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5-Amino-5'-bromo-6-(4-methyl-benzo-yl)-8-nitro-2,3-di-hydro-1H-spiro-[imidazo[1,2-a]pyridine-7,3'-indolin]-2'-one including an unknown solvate. | In the title compound, C22H18BrN5O4, the central six-membered ring, derived from 1,4-di-hydro-pyridine, adopts a distorted boat conformation with a puckering amplitude of 0.197 (3) Å, the imidazole ring adopts a twisted conformation with a puckering amplitude of 0.113 (3) Å, and the oxindole moiety is planar with an r.... | 25,161,594 | [
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2',7'-Di-bromo-spiro-[cyclo-propane-1,9'-fluorene]. | In the title compound, C15H10Br2, each mol-ecule is situated on special postion mm, so the asymmetric unit contains one-quater of a mol-ecule. The 2,7-di-bromo-9H-fluorene fragment and three spiro-cyclo-propane C atoms lie on different planes, which are perpendicular to each other. In the crystal, π-π inter-actions bet... | 25,161,597 | [
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Bending and twisting the embryonic heart: a computational model for c-looping based on realistic geometry. | The morphogenetic process of cardiac looping transforms the straight heart tube into a curved tube that resembles the shape of the future four-chambered heart. Although great progress has been made in identifying the molecular and genetic factors involved in looping, the physical mechanisms that drive this process have... | 25,161,623 | [
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Onset of the spring bloom in the northwestern Mediterranean Sea: influence of environmental pulse events on the in situ hourly-scale dynamics of the phytoplankton community structure. | Most of phytoplankton influence is barely understood at the sub meso scale and daily scale because of the lack of means to simultaneously assess phytoplankton functionality, dynamics and community structure. For a few years now, it has been possible to address this objective with an automated in situ high frequency sam... | 25,161,647 | [
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A Case Report of Acute Acalculous Cholecystitis and Acute Hemorrhagic Cystitis due to Salmonella Typhi. | Acute acalculous cholecystitis and acute hemorrhagic cystitis due to Salmonella Typhi are a rare condition. A 24-year-old female patient was admitted to our clinic with abdominal pain, nausea, fever, headache, urinary burning, and bloody urine. Based on clinical, laboratory, and radiological evaluations, the patient wa... | 25,161,668 | [
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The sustainability of interventions of a community-based trial on children and adolescents' healthy lifestyle. | Sustainability is the core of a successful health-related intervention program. This study was conducted to evaluate the sustainability of interventions of the Heart Health Promotion from Childhood (HHPC) project, one of the 10 interventional projects of the Isfahan Healthy Heart Program. The evaluation of HHPC include... | 25,161,679 | [
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Pyrroloquinoline Quinone Induces Cancer Cell Apoptosis via Mitochondrial-Dependent Pathway and Down-Regulating Cellular Bcl-2 Protein Expression. | Pyrroloquinoline quinone (PQQ) has been reported as a promising agent that might contribute to tumor cell apoptosis and death, yet little is known on its mechanisms. In current study, the effect of PQQ on cell proliferation and mitochondrial-dependent apoptosis were examined in 3 solid tumor cell lines (A549, Neuro-2A ... | 25,161,699 | [
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Influence of perylenediimide-pyrene supramolecular interactions on the stability of DNA-based hybrids: Importance of electrostatic complementarity. | Aromatic π-π stacking interactions are ubiquitous in nature, medicinal chemistry and materials sciences. They play a crucial role in the stacking of nucleobases, thus stabilising the DNA double helix. The following paper describes a series of chimeric DNA-polycyclic aromatic hydrocarbon (PAH) hybrids. The PAH building ... | 25,161,715 | [
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The chemoenzymatic synthesis of clofarabine and related 2'-deoxyfluoroarabinosyl nucleosides: the electronic and stereochemical factors determining substrate recognition by E. coli nucleoside phosphorylases. | Two approaches to the synthesis of 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine (1, clofarabine) were studied. The first approach consists in the chemical synthesis of 2-deoxy-2-fluoro-α-D-arabinofuranose-1-phosphate (12a, (2F)Ara-1P) via three step conversion of 1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-ar... | 25,161,724 | [
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Synthesis of rigid p-terphenyl-linked carbohydrate mimetics. | An approach to β-D-2-aminotalose- and β-D-2-aminoidose-configured carbohydrate mimetics bearing a phenyl substituent is described. Unnatural divalent rigid p-terphenyl-linked C-aryl glycosides with 2.0 nm dimension are available using Suzuki cross-couplings. The key compound, a p-bromophenyl-substituted 1,2-oxazine, wa... | 25,161,733 | [
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Copolymerization and terpolymerization of carbon dioxide/propylene oxide/phthalic anhydride using a (salen)Co(III) complex tethering four quaternary ammonium salts. | The (salen)Co(III) complex 1 tethering four quaternary ammonium salts, which is a highly active catalyst in CO2/epoxide copolymerizations, shows high activity for propylene oxide/phthalic anhydride (PO/PA) copolymerizations and PO/CO2/PA terpolymerizations. In the PO/PA copolymerizations, full conversion of PA was achi... | 25,161,738 | [
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One-pot stereoselective synthesis of α,β-differentiated diamino esters via the sequence of aminochlorination, aziridination and intermolecular SN2 reaction. | We report here an efficient one-pot method for the synthesis of α,β-differentiated diamino esters directly from cinnamate esters using N,N-dichloro-p-toluenesulfonamide and benzylamine as nitrogen sources. The key transformations include a Cu-catalyzed aminohalogenation and aziridination, followed by an intermolecular ... | 25,161,740 | [
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Solitary mediastinal lymph node recurrence after curative resection of colon cancer. | We report two cases of solitary mediastinal lymph node recurrence after colon cancer resection. Both cases had para-aortic lymph node metastasis at the time of initial surgery and received adjuvant chemotherapy for 4 years in case 1 and 18 mo in case 2. The time to recurrence was more than 8 years in both cases. After ... | 25,161,766 | [
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Successful venous angioplasty of superior vena cava syndrome after heart transplantation. | Introduction. For patients with terminal heart failure, heart transplantation (HTX) has become an established therapy. Before transplantation there are many repeated measurements with a pulmonary artery catheter (PAC) via the superior vena cava (SVC) necessary. After transplantation, endomyocardial biopsy (EMB) is reco... | 25,161,772 | [
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Elizabethkingia meningosepticum in a Patient with Six-Year Bilateral Perma-Catheters. | Elizabethkingia meningosepticum (EM) is a saprophyte which is ubiquitous in nature, but not normally present in the human flora. Instances of infection are rare in the USA, but EM may be an emerging pathogen among immune-compromised patients. EM can cause a variety of infections, but nosocomial pneumonia and bacteremia... | 25,161,782 | [
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Infection Related Glomerulonephritis Associated with Staphylococcus epidermidis in the Absence of Prosthetic Material. | We report a case of a 72-year-old diabetic male who developed infection-related glomerulonephritis (IRGN) in the setting of severe Staphylococcus epidermidis infection. He required renal replacement therapy for 6 weeks, but had full recovery of his kidney function with aggressive treatment of the infection. While this ... | 25,161,783 | [
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Palliative surgery for rare cases of anterior urethral metastasis in prostate cancer. | Penis metastasis from prostate cancer is very rare, and its management varies from case to case as there are very few cases reported in the literature. We describe a patient with prostate cancer treated with radiotherapy and androgen deprivation therapy who presented with urethral bleeding as a symptom of anterior uret... | 25,161,796 | [
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Malignant pleural and peritoneal mesothelioma consequential to brief indirect asbestos exposure. | This report highlights that pleural and peritoneal mesothelioma can occur without direct asbestos exposure as was seen in our young patient. The patient had indirect exposure for as short as 3 months as a child, 15 years earlier, when she was residing with her miner father in the district of Jharia, Jharkhand, which is... | 25,161,804 | [
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Severe aortic coarctation in an adult patient with normal brachial blood pressure. | The present case shows that a normal brachial blood pressure (BP) does not exclude severe coarctation and should be considered in normotensive patients presenting with a systolic murmur and/or unexplained severe left ventricular hypertrophy. Congenital coarctation of the aorta is a narrowing of the descending aorta, us... | 25,161,810 | [
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The neuroanatomical correlates of anxiety in a healthy population: differences between the State-Trait Anxiety Inventory and the Hamilton Anxiety Rating Scale. | The State-Trait Anxiety Inventory (STAI) and the Hamilton scale for anxiety (HARS) are two of the most important scales employed in clinical and psychological realms for the evaluation of anxiety. Although the reliability and sensibility of these scales are widely demonstrated there is an open debate on what exactly th... | 25,161,817 | [
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Methods for rapid frequency-domain characterization of leakage currents in silicon nanowire-based field-effect transistors. | Silicon nanowire-based field-effect transistors (SiNW FETs) have demonstrated the ability of ultrasensitive detection of a wide range of biological and chemical targets. The detection is based on the variation of the conductance of a nanowire channel, which is caused by the target substance. This is seen in the voltage... | 25,161,832 | [
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Double layer effects in a model of proton discharge on charged electrodes. | We report first results on double layer effects on proton discharge reactions from aqueous solutions to charged platinum electrodes. We have extended a recently developed combined proton transfer/proton discharge model on the basis of empirical valence bond theory to include specifically adsorbed sodium cations and chl... | 25,161,833 | [
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Molecular biology approaches in bioadhesion research. | The use of molecular biology tools in the field of bioadhesion is still in its infancy. For new research groups who are considering taking a molecular approach, the techniques presented here are essential to unravelling the sequence of a gene, its expression and its biological function. Here we provide an outline for a... | 25,161,834 | [
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A nanometric cushion for enhancing scratch and wear resistance of hard films. | Scratch resistance and friction are core properties which define the tribological characteristics of materials. Attempts to optimize these quantities at solid surfaces are the subject of intense technological interest. The capability to modulate these surface properties while preserving both the bulk properties of the ... | 25,161,836 | [
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Nanocavity crossbar arrays for parallel electrochemical sensing on a chip. | We introduce a novel device for the mapping of redox-active compounds at high spatial resolution based on a crossbar electrode architecture. The sensor array is formed by two sets of 16 parallel band electrodes that are arranged perpendicular to each other on the wafer surface. At each intersection, the crossing bars a... | 25,161,846 | [
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Purification of ethanol for highly sensitive self-assembly experiments. | Ethanol is the preferred solvent for the formation of self-assembled monolayers (SAMs) of thiolates on gold. By applying a thin film sensor system, we could demonstrate that even the best commercial qualities of ethanol contain surface-active contaminants, which can compete with the desired thiolates for surface sites.... | 25,161,861 | [
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Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes. | The fatty acid binding protein 4 (FABP4), one of the most abundant proteins in adipocytes, has been reported to have a proinflammatory function in macrophages. However, the physiological role of FABP4, which is constitutively expressed in adipocytes, has not been fully elucidated. Previously, we demonstrated that FABP4... | 25,161,868 | [
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Red foxes (Vulpes vulpes) and wild dogs (dingoes (Canis lupus dingo) and dingo/domestic dog hybrids), as sylvatic hosts for Australian Taenia hydatigena and Taenia ovis. | Foxes (n = 499), shot during vertebrate pest control programs, were collected in various sites in the Australian Capital Territory (ACT), New South Wales (NSW) and Western Australia (WA). Wild dogs (dingoes (Canis lupus dingo) and their hybrids with domestic dogs) (n = 52) captured also as part of vertebrate pest contr... | 25,161,904 | [
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Sentinels in a climatic outpost: Endoparasites in the introduced muskox (Ovibos moschatus wardi) population of Dovrefjell, Norway. | We assessed the occurrence of endoparasite eggs, cysts, oocysts and larvae in the muskox population of Dovrefjell, Norway, during June and August 2012. This population originates from 13 calves translocated from Eastern Greenland during the 1950s. A total of 167 faecal samples were collected, of which 49% came from ide... | 25,161,914 | [
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Ethnomedical properties of taxus wallichiana zucc. (Himalayan yew). | Taxus wallichiana Zucc., known as Himalayan yew, belongs to the family Taxaceae. It is a medium-sized, temperate, Himalayan forest tree of medicinal importance. In India, this evergreen tree is found at altitudes between 1800 and 3300 m above mean sea level (MSL). It has been used by the native populations for treating... | 25,161,920 | [
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A Comparison of Food-grade Folium mori ( Sāng Yè) Extract and 1-Deoxynojirimycin for Glycemic Control and Renal Function in Streptozotocin-induced Diabetic Rats. | Folium mori ( Sāng Yè, leaf of Morus alba L.; FM) is known to possess hypoglycemic effects, and 1-deoxynojirimycin (1-DNJ) has been proposed as an important functional compound in FM. However, the hypoglycemic activity of purified 1-DNJ has been rarely studied. It is also not known how FM and 1-DNJ affect the developme... | 25,161,921 | [
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Bevacizumab treatment reduces retinal neovascularization in a mouse model of retinopathy of prematurity. | To evaluate the effect of different bevacizumab concentrations on retinal neovascularization in a retinopathy of prematurity (ROP) mouse model. A total of 60 of C57BL/6 J mice were exposed to 75%±2% oxygen from postnatal d7 to postnatal d12. Fifteen nonexposed mice served as negative controls (group A). On d12, 30 mice... | 25,161,929 | [
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Evaluation of the effects of acyclovir and/or human amniotic membrane on herpes virus culture and quantitative virus inactivity by real-time polymerase chain reaction. | To investigate the permeability of amniotic membrane in herpes virus cell culture to acyclovir with real time polymerase chain reaction (RT-PCR). Madin-Darby Bovine Kidney (MDBK) cell culture and Bovine Herpes Virus (BHV1) type 1 were used in the study. Cell cultures were grouped into two on the basis of herpes virus i... | 25,161,932 | [
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Femtosecond laser-assisted deep anterior lamellar keratoplasty for keratoconus and keratectasia. | To describe the initial outcomes and safety of femtosecond laser-assisted deep anterior lamellar keratoplasty (DALK) for keratoconus and post-LASIK keratectasia. In this non-comparative case series, 10 eyes of 9 patients underwent DALK procedures with a femtosecond laser (Carl Zeiss Meditec AG, Jena, Germany). Of the 9... | 25,161,934 | [
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Presence of thyroid-associated ophthalmopathy in Hashimoto's thyroiditis. | To determine the prevalence of ophthalmopathy in Hashimoto's patients and to make a comparison in subgroups of patients. The study involved 110 Hashimoto's thyroiditis patients and 50 control subjects attending to the endocrinology department of the hospital. Subgroup classification of patients was made as euthyroid, s... | 25,161,935 | [
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Diagnosis of lacrimal canalicular diseases using ultrasound biomicroscopy: a preliminary study. | To evaluate the application of ultrasound biomicroscopy (UBM) in the examination of lacrimal canalicular diseases, and to investigate UBM image characteristics of lacrimal canaliculi in disease states. Sixty cases (63 eyes, 69 canaliculi) of lacrimal canalicular diseases were enrolled that included 32 patients (32 eyes... | 25,161,938 | [
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Birth weight and gestational age on retinopathy of prematurity in discordant twins in China. | To assess the relative effect of birth weight and gestational age on retinopathy of prematurity (ROP) using preterm twin pairs discordant for birth weigh in a tertiary neonatal intensive care unit in China. Fifty-six discordant twin pairs of 112 preterm infants were retrospectively analyzed. The twin pairs were divided... | 25,161,939 | [
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Role of wide-field autofluorescence imaging and scanning laser ophthalmoscopy in differentiation of choroidal pigmented lesions. | To evaluate the diagnostic properties of wide-field fundus autofluorescence (FAF) scanning laser ophthalmoscope (SLO) imaging for differentiating choroidal pigmented lesions. A consecutive series of 139 patients were included, 101 had established choroidal melanoma with 13 untreated lesions and 98 treated with radiothe... | 25,161,946 | [
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Chromosomal islands of Streptococcus pyogenes and related streptococci: molecular switches for survival and virulence. | Streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. Virulence in S. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (CI). S. pyogenes phage-like chromosomal islands (SpyCI) confer a complex mutator phenoty... | 25,161,960 | [
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Awareness and Practices of Oral Hygiene and its Relation to Sociodemographic Factors among Patients attending the General Outpatient Department in a Tertiary Care Hospital of Kolkata, India. | Periodontal diseases, dental caries, malocclusion, and oral cancer are the most prevalent dental diseases affecting people in the Indian community. The study was conducted to assess the awareness and practices on oral hygiene and its association with the sociodemographic factors among patients attending the general Out... | 25,161,965 | [
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Dengue Fever with rectus sheath hematoma: a case report. | Dengue fever, also known as breakbone fever, is an infectious tropical disease caused by the Dengue virus. It is associated with a number of complications, which are well documented. However, Dengue fever associated with rectus sheath hematoma (RSH) is a very rare complication. Only one case report has been published p... | 25,161,976 | [
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The effects of multi-strain probiotic compound on symptoms and quality-of-life in patients with irritable bowel syndrome: A randomized placebo-controlled trial. | Evidence has shown beneficial effects of probiotics in the treatment of irritable bowel syndrome (IBS); however, there is still a lack of data in this regard. We evaluated the efficacy of a multi-strain probiotic compound on IBS symptoms and quality-of-life (QOL). Adult IBS patients (n = 132) were randomized to receive... | 25,161,987 | [
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Interactions between E-cadherin and microRNA deregulation in head and neck cancers: the potential interplay. | E-cadherin expression in the head and neck epithelium is essential for the morphogenesis and homeostasis of epithelial tissues. The cadherin-mediated cell-cell contacts are required for the anchorage-dependent growth of epithelial cells. Further, survival and proliferation require physical tethering created by proper c... | 25,161,999 | [
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A discrete wavelet based feature extraction and hybrid classification technique for microarray data analysis. | Cancer classification by doctors and radiologists was based on morphological and clinical features and had limited diagnostic ability in olden days. The recent arrival of DNA microarray technology has led to the concurrent monitoring of thousands of gene expressions in a single chip which stimulates the progress in can... | 25,162,043 | [
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MnO2 spontaneously coated on carbon nanotubes for enhanced water oxidation. | δ-MnO2/o-MWCNTs were synthesized by coating MnO2 spontaneously on oxidized multi-walled carbon nanotubes via simple immersion of the o-MWCNTs into KMnO4 solution. This catalyst comprising the outer region of catalytic MnO2 and the inner region of highly conductive o-MWCNTs enhanced photocatalytic water oxidation activi... | 25,162,068 | [
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Controlling and monitoring exposure to radiation from medical imaging. | Above a certain threshold dose, ionising radiation invariably provokes harmful effects such as burns, nausea and aplasia. Their severity increases with the dose received. There is no known threshold dose below which long-term harmful effects, such as cancer and genetic defects, do not occur. Ionising radiation comes fr... | 25,162,100 | [
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NMR structure of the human Rad18 zinc finger in complex with ubiquitin defines a class of UBZ domains in proteins linked to the DNA damage response. | Ubiquitin-mediated interactions are critical for the cellular DNA damage response (DDR). Therefore, many DDR-related proteins contain ubiquitin-binding domains, including ubiquitin-binding zinc fingers (UBZs). The majority of these UBZ domains belong to the C2H2 (type 3 Polη-like) or C2HC (type 4 Rad18-like) family. We... | 25,162,118 | [
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Medications development for substance-use disorders: contextual influences (dis)incentivizing pharmaceutical-industry positioning. | The significant contribution of substance-use disorders (SUDs) to the global-disease burden and associated unmet medical needs has not engendered a commensurate level of pharma-industry research and development (R&D) for novel SUD therapeutics invention. Analysis of contextual factors shaping this position suggests... | 25,162,124 | [
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A palladium-catalyzed three-component-coupling strategy for the differential vicinal diarylation of terminal 1,3-dienes. | A palladium-catalyzed intermolecular vicinal diarylation of terminal 1,3-dienes using aryldiazonium tetrafluoroborates and arylboronic acids is reported. Using this technology, two different arenes are regioselectively introduced in a vicinal fashion across the terminal alkene of a variety of terminal 1,3-dienes at amb... | 25,162,125 | [
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Impact of altered lower limb proprioception produced by tendon vibration on adaptation to split-belt treadmill walking. | It has been proposed that proprioceptive input is essential to the development of a locomotor body schema that is used to guide the assembly of successful walking. Proprioceptive information is used to signal the need for, and promotion of, locomotor adaptation in response to environmental or internal modifications. Th... | 25,162,146 | [
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Interference between conscious and unconscious facial expression information. | There is ample evidence to show that many types of visual information, including emotional information, could be processed in the absence of visual awareness. For example, it has been shown that masked subliminal facial expressions can induce priming and adaptation effects. However, stimulus made invisible in different... | 25,162,153 | [
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Cognitive impairment is a risk factor for delayed analgesia in older people with long bone fracture: a multicenter exploratory study. | ABSTRACT Background: Older people who present to the emergency department (ED) often experience a significant delay to analgesia. This study compares the time to analgesia for cognitively impaired and cognitively intact older people diagnosed with a long bone fracture. Methods: The aim of the study was to determine if ... | 25,162,158 | [
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Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). | The recent discovery of allosteric modulators of the CB1 receptor including PSNCBAM-1 (4) has generated significant interest in CB1 receptor allosteric modulation. Here in the first SAR study on 4, we have designed and synthesized a series of analogs focusing on modifications at two positions. Pharmacological evaluatio... | 25,162,172 | [
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Solvatochromic probe response within ionic liquids and their equimolar mixtures with tetraethylene glycol. | Synergism in a probe response within a mixture hints at the presence of strong interactions involving the solvent constituents of the mixture and possibly the probe. Unusual and rare "hyperpolarity" resulting from the synergism in probe response exhibited by ionic liquid (IL) mixtures with glycol family solvents is inv... | 25,162,184 | [
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Role of pharmacogenomics in dialysis and transplantation. | Pharmacogenomics is the study of differences in drug response on the basis of individual genetic background. With rapidly advancing genomic technologies and decreased costs of genotyping, the field of pharmacogenomics continues to develop. Application to patients with kidney disease provides growing opportunities for i... | 25,162,201 | [
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Quantification of lamotrigine in patient plasma using a fast liquid chromatography-tandem mass spectrometry method with backflush technology. | Recent concerns have been raised by neurologists and patients with epilepsy regarding the bioequivalence of generic lamotrigine to the brand Lamictal. Bioequivalence studies require the quantification of lamotrigine in human plasma, including in the presence of other drugs, for studies that will use patients with epile... | 25,162,213 | [
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Dynamic response of CoSb2O6 trirutile-type oxides in a CO2 atmosphere at low-temperatures. | Experimental work on the synthesis of the CoSb2O6 oxide and its CO2 sensing properties is presented here. The oxide was synthesized by a microwave-assisted colloidal method in presence of ethylenediamine after calcination at 600 °C. This CoSb2O6 oxide crystallized in a tetragonal structure with cell parameters a = 4.64... | 25,162,232 | [
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0.04381858,
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C-H activation and metalation at electrode surfaces: 2,3-dimethyl-1,4-dihydroxybenzene on Pd(pc) and Pd(111) studied by TLE, HREELS and DFT. | Previous studies, based on thin-layer electrochemistry (TLE), in situ scanning tunneling microscopy (EC-STM), high-resolution electron energy loss spectroscopy (HREELS) and density functional theory (DFT) computations, on the chemical adsorption of hydroquinone from aqueous solutions onto atomically smooth Pd (and Pt) ... | 25,162,298 | [
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0.1771461,
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Early markers are present in both embryogenesis pathways from microspores and immature zygotic embryos in cork oak, Quercus suber L. | In Quercus suber, cork oak, a Mediterranean forest tree of economic and social interest, rapid production of isogenic lines and clonal propagation of elite genotypes have been achieved by developing in vitro embryogenesis from microspores and zygotic embryos respectively. Despite its high potential in tree breeding str... | 25,162,300 | [
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0.4067253,
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Comparison of clinicopathologic features and survival of histopathologically amelanotic and pigmented melanomas: a population-based study. | IMPORTANCE Previous studies have reported that histopathologically amelanotic melanoma is associated with poorer survival than pigmented melanoma; however, small numbers of amelanotic melanomas, selected populations, lack of centralized pathologic review, or no adjustment for stage limit the interpretation or generaliz... | 25,162,299 | [
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0.08084708,
0.3100398,
0.123418,
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... |
Living With a Smoker and Physical Inactivity: An Unexplored Health Behavior Pathway. | The present study investigated an unexplored health behavior pathway: the association between living with a smoker and physical inactivity. The study performed an analysis of cross-sectional data from the second wave of the Survey of Midlife Development in the United States (2004-2006). The sample included 1050 women a... | 25,162,327 | [
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0.2307468,
0.4878995,
0.019669... |
A physical-cognitive intervention to enhance gait speed in older Mexican adults. | To test the effects of a physical-cognitive exercise intervention on gait parameters under dual-task conditions in community-dwelling older adults. A repeated-measures quasi-experimental design, with control and exercise groups, was used. Study participants consist of a convenience sample recruited from senior citizens... | 25,162,328 | [
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0.1259615,
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0.03014709,
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Polyethylene glycol 4000 for treatment of functional constipation in children. | The aim of the study was to evaluate the effectiveness and safety of 2 different polyethylene glycol (PEG) doses for the maintenance treatment of functional constipation in children. Children with functional constipation according to the Rome III criteria were randomly assigned to receive PEG 4000 at a dose of either 0... | 25,162,362 | [
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... |
Macroscopic nanotube fibers spun from single-walled carbon nanotube polyelectrolytes. | In this work, single-walled carbon nanotube (SWCNT) fibers were produced from SWCNT polyelectrolyte dispersions stabilized by crown ether in dimethyl sulfoxide and coagulated into aqueous solutions. The SWCNT polyelectrolyte dispersions had concentrations up to 52 mg/mL and showed liquid crystalline behavior under pola... | 25,162,378 | [
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0.3669443,
0.3142634,
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Space management: a technique for esthetic, conservative treatment of congenitally missing teeth. | The successful treatment of congenitally missing teeth (CMT) a common dental anomaly that affects third molars and lateral incisors requires addressing multiple challenges that frequently accompany the missing teeth. The biggest concern among patients presenting with CMT usually is esthetics. In this case report, an in... | 25,162,390 | [
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0.08104739,
... |
A semi-automated technique determining the liver standardized uptake value reference for tumor delineation in FDG PET-CT. | 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)-computed tomography (CT) has been an essential modality in oncology. We propose a semi-automated algorithm to objectively determine liver standardized uptake value (SUV), which is used as a threshold for tumor delineation. A large spherical volume of inter... | 25,162,396 | [
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0.3325623,
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Inference of gene regulatory networks incorporating multi-source biological knowledge via a state space model with L1 regularization. | Comprehensive understanding of gene regulatory networks (GRNs) is a major challenge in the field of systems biology. Currently, there are two main approaches in GRN analysis using time-course observation data, namely an ordinary differential equation (ODE)-based approach and a statistical model-based approach. The ODE-... | 25,162,401 | [
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... |
The conflict between cheetahs and humans on Namibian farmland elucidated by stable isotope diet analysis. | Large areas of Namibia are covered by farmland, which is also used by game and predator species. Because it can cause conflicts with farmers when predators, such as cheetahs (Acinonyx jubatus), hunt livestock, we assessed whether livestock constitutes a significant part of the cheetah diet by analysing the stable isoto... | 25,162,403 | [
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0.02231991,
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Bleeding in Knee Arthroplasty: Age, Drained Volume, and Ischemia Time. | Drainages in primary knee arthroplasty remain unclear. Our aim is to analyze variables that may affect bleeding in knee arthroplasty (age, drained volume, and ischemia time). We included 188 knee arthroplasties, divided into three groups: conventional approach for total knee arthroplasty (TKA), minimally invasive total... | 25,162,405 | [
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0.3422899,
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0.1418333,
0.2... |
Use of Transcutaneous Electrical Nerve Stimulation Device in Early Osteoarthritis of the Knee. | Some have proposed the use of transcutaneous electrical nerve stimulation (TENS) as an adjunct to the current standard of care in treatment of osteoarthritis knee pain. The purpose of this study was to evaluate the effects of TENS on the following issues in patients who have early-stage osteoarthritis of the knee: (1) ... | 25,162,407 | [
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0.03508153,
0.303717... |
A Prospective, Longitudinal Study of Patient Activity Levels Following Total Knee Arthroplasty Stratified by Demographic and Comorbid Factors. | With the marked increase in the annual number of total knee arthroplasties (TKAs) in the United States, there has been an increased interest in evaluating patient-reported outcomes. The purpose of this study was to prospectively and longitudinally evaluate temporal trends in patient activity levels following TKA and to... | 25,162,408 | [
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0.2769875,
0.2799872,
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0.2153486,
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... |
Gilles de la Tourette syndrome and disruptive behavior disorders: prevalence, associations, and explanation of the relationships. | Gilles de la Tourette syndrome and conduct disorder (CD) are both heterogeneous childhood onset conditions, and although patients with CD have been described in Gilles de la Tourette syndrome cohorts, little is known about the etiology of CD in Gilles de la Tourette syndrome or of the interrelationships. A cohort of 57... | 25,162,416 | [
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0.2784982,
0.25882,
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... |
A critical role for the mTORC2 pathway in lung fibrosis. | A characteristic of dysregulated wound healing in IPF is fibroblastic-mediated damage to lung epithelial cells within fibroblastic foci. In these foci, TGF-β and other growth factors activate fibroblasts that secrete growth factors and matrix regulatory proteins, which activate a fibrotic cascade. Our studies and those... | 25,162,417 | [
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... |
Nuclear medicine practices in the 1950s through the mid-1970s and occupational radiation doses to technologists from diagnostic radioisotope procedures. | Data on occupational radiation exposure from nuclear medicine procedures for the time period of the 1950s through the 1970s is important for retrospective health risk studies of medical personnel who conducted those activities. However, limited information is available on occupational exposure received by physicians an... | 25,162,420 | [
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0.07645327,
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0.374173,
0.05875633... |
Homologous cloning, purification and characterization of highly active cellobiohydrolase I (Cel7A) from Penicillium canescens. | Penicillium canescens is a filamentous fungus that normally does not secrete notable levels of cellulase activity. Cellobiohydrolase I of P. canescens (PcCel7A) was homologously cloned into a host strain RN3-11-7 (niaD-) and then expressed under the control of a strong xylA promoter. Using three steps of chromatography... | 25,162,433 | [
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0.1692464,
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0.1095858,
-... |
Light and Dark of Reactive Oxygen Species for Vascular Function: 2014 ASVB (Asian Society of Vascular Biology). | Vascular-derived hydrogen peroxide (H2O2) serves as an important signaling molecule in the cardiovascular system and contributes to vascular homeostasis. H2O2 is a second messenger, transducing the oxidative signal into biological responses through posttranslational protein modification. The balance between oxidant and... | 25,162,437 | [
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... |
Percutaneous left atrial appendage closure for stroke prevention. | In atrial fibrillation (AF) patients with an increased stroke risk, oral anticoagulation (OAC) is the standard treatment for stroke prevention. However, this therapy carries a high risk of major bleeding. Percutaneous closure of the left atrial appendage (LAA) is suggested as an alternative option for stroke prevention... | 25,162,439 | [
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0.1778474,
0.1444173,
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Bone marrow involvement is not manifest in the early stages of childhood acute lymphoblastic leukaemia. | Acute lymphoblastic leukaemia (ALL) in children may have atypical presentations causing diagnostic delay. Guidelines for prompt referral have been published. The utility of the specified criteria is unknown. Symptoms, signs and laboratory findings at the time of diagnosis were reviewed in a consecutive series of 100 ch... | 25,162,442 | [
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... |
Non-radiographic intraoperative fluorescent cholangiography is feasible. | Intraoperative fluorescent cholangiography (IFC) with concomitant fluorescent angiography was recently developed for non-invasive identification of the anatomy during laparoscopic cholecystectomy. The objective of this study was to assess the time required for routine-use of IFC and to evaluate the success rate of the ... | 25,162,446 | [
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0.01944318,... |
Linear versus branched poly-lysine/arginine as polarity enhancer tags. | The design and synthesis of Lys- and Arg-containing peptides as solubilizing tags were studied to evaluate their influence on polarity. The relevance of spatial arrangement of polar groups, in α- or ε-amino positions, was confirmed by chromatographic analysis of a rational PolyLys-based synthesized structure. The most ... | 25,162,452 | [
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0.1473267,
0.3421921,
0.02609095,
-0.05847886,
0.1... |
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