title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Complete mitochondrial genome of the yellow-banded sweetlips Plectorhinchus lineatus (Perciformes: Haemulidae). | The complete mitochondrial genome of yellow-banded sweetlips Plectorhinchus lineatus was determined in this study. The genome was 16,548 bp in length and consisted of 13 protein-coding genes, 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes, and one non-coding control region. The overall base composition was ... | 25,162,454 | [
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A preliminary study on methylphenidate-regulated gene expression in lymphoblastoid cells of ADHD patients. | Methylphenidate (MPH) is a commonly used stimulant medication for treating attention-deficit/hyperactivity disorder (ADHD). Besides inhibiting monoamine reuptake there is evidence that MPH also influences gene expression directly. We investigated the impact of MPH treatment on gene expression levels of lymphoblastoid c... | 25,162,476 | [
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Single CuO(x) nanowire memristor: forming-free resistive switching behavior. | CuOx nanowires were synthesized by a low-cost and large-scale electrochemical process with AAO membranes at room temperature and its resistive switching has been demonstrated. The switching characteristic exhibits forming-free and low electric-field switching operation due to coexistence of significant amount of defect... | 25,162,489 | [
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VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury. | Liver repair after acute liver injury is characterized by hepatocyte proliferation, removal of necrotic tissue, and restoration of hepatocellular and hepatic microvascular architecture. Macrophage recruitment is essential for liver tissue repair and recovery from injury; however, the underlying mechanisms are unclear. ... | 25,162,491 | [
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Gynecologic disorders diagnosed during deployment to Southwest/Central Asia, active component females, U.S. Armed Forces, 2008-2013. | Service women in the U.S. Armed Forces face unique challenges that may lead to or exacerbate gynecologic disorders - particularly during deployment. This report documented that approximately one in 10 military women who served in Southwest/Central Asia were diagnosed with a gynecologic disorder at least once during dep... | 25,162,497 | [
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Update: Routine screening for antibodies to human immunodeficiency virus, civilian applicants for U.S. military service and U.S. Armed Forces, active and reserve components, January 2009-June 2014. | This report contains an update through June 2014 of the results of routine screening for antibodies to the human immunodeficiency virus (HIV) among civilian applicants for military service and among members of the active and reserve components of the U.S. Armed Forces. Seroprevalences among civilian applicants in 2013 ... | 25,162,499 | [
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The complete mitochondrial genome of the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae). | The complete mitochondrial genome (mitogenome) of Tribolium castaneum (Coleoptera: Tenebrionidae) was determined to be 15,883 bp (GenBank accession No. KM009121), which contains 22 tRNA genes, 13 protein-coding genes (PCGs), 2 rRNA genes and a major non-coding A + T-rich region. It has the typical gene organization and... | 25,162,515 | [
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Hemagglutinin 222D/G polymorphism facilitates fast intra-host evolution of pandemic (H1N1) 2009 influenza A viruses. | The amino acid substitution of aspartic acid to glycine in hemagglutinin (HA) in position 222 (HA-D222G) as well as HA-222D/G polymorphism of pandemic (H1N1) 2009 influenza viruses (A(H1N1)pdm09) were frequently reported in severe influenza in humans and mice. Their impact on viral pathogenicity and the course of influ... | 25,162,520 | [
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Medical management of children after liver transplantation. | Successful outcomes in patient, graft survival, and quality of life depend on the prevention, early detection, and treatment of possible complications. The aim of the study was to highlight the common outcomes focusing on the unique features in children. Medical follow-up of children after liver transplantation include... | 25,162,538 | [
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Clinical characteristics of the inhabitants of an internally displaced persons camp in Brazzaville, Republic of Congo after the arms dump blast on March 4, 2012. | On March 4, 2012, an arms dump exploded in a densely populated area in Brazzaville, Republic of the Congo. At least 250 people were killed, 2,500 wounded, and 13,800 left homeless, of which 5,000 were relocated to a newly constructed internally displaced person (IDP) camp. To describe the medical complaints of persons ... | 25,162,541 | [
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Cephalometric effects of the Jones Jig appliance followed by fixed appliances in Class II malocclusion treatment. | The aim of this study was to cephalometrically assess the skeletal and dentoalveolar effects of Class II malocclusion treatment performed with the Jones Jig appliance followed by fixed appliances. The sample comprised 25 patients with Class II malocclusion treated with the Jones Jig appliance followed by fixed applianc... | 25,162,565 | [
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Phase conversion from hexagonal CuS(y)Se(1-y) to cubic Cu(2-x)S(y)Se(1-y): composition variation, morphology evolution, optical tuning, and solar cell applications. | In this work, we report a simple and low-temperature approach for the controllable synthesis of ternary Cu-S-Se alloys featuring tunable crystal structures, compositions, morphologies, and optical properties. Hexagonal CuS(y)Se(1-y) nanoplates and face centered cubic (fcc) Cu(2-x)S(y)Se(1-y) single-crystal-like stacked... | 25,162,581 | [
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Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells. | Membrane type 1-matrix metalloproteinase (MT1-MMP) functions as a signaling molecule in addition to a proteolytic enzyme. Our hypothesis was that MT1-MMP cooperates with protein kinase B (Akt) in tumor necrosis factor (TNF)-α-induced signaling pathways of vascular responses, including tissue factor (TF) procoagulant ac... | 25,162,582 | [
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Current perspectives on the therapeutic aspects of chronic myelogenous leukemia. | Chronic myelogenous leukemia (CML) is a myeloproliferative disorder arising from the malignant transformation of normal myeloid cells. Its genetic hallmark is the presence of Philadelphia chromosome translocation which results in fusion of the breakpoint cluster region and abelson genes. The study aims to evaluate the ... | 25,162,589 | [
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Impact of physical manipulation on in vitro and in vivo release profiles of oxycodone DETERx®: an extended-release, abuse-deterrent formulation. | In vitro: To assess the effect of common crushing techniques on particle size reduction (PSR) and in vitro drug-release kinetics of oxycodone DETERx® (herein DETERx) and of a commercially available oxycodone extended-release (ER) tablet. In vivo: To evaluate the impact of the most effective manipulation method identifi... | 25,162,603 | [
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Remifentanil target-controlled infusion: a safe rescue protocol for unexpected severe postoperative pain. | Three cases are reported here in which remifentanil administered as a target-controlled infusion (TCI) was used in Post Anesthesia Care Unit as a fast rescue treatment for acute and unexpected severe postoperative pain, allowing subsequent clinical evaluation and rational titration of analgesia with longer acting opioi... | 25,162,608 | [
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Introducing sexual orientation and gender identity into the electronic health record: one academic health center's experience. | Many U.S. populations experience significant health disparities. Increasing health care providers' awareness of and education about sexual orientation (SO) and gender identity (GI) diversity could help reduce health disparities among lesbian, gay, bisexual, and transgender (LGBT) patients. The authors share the Univers... | 25,162,618 | [
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Upregulation of leukemia inhibitory factor (LIF) during the early stage of optic nerve regeneration in zebrafish. | Fish retinal ganglion cells (RGCs) can regenerate their axons after optic nerve injury, whereas mammalian RGCs normally fail to do so. Interleukin 6 (IL-6)-type cytokines are involved in cell differentiation, proliferation, survival, and axon regrowth; thus, they may play a role in the regeneration of zebrafish RGCs af... | 25,162,623 | [
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Funding infectious disease research: a systematic analysis of UK research investments by funders 1997-2010. | Research investments are essential to address the burden of disease, however allocation of limited resources is poorly documented. We systematically reviewed the investments awarded by funding organisations to UK institutions and their global partners for infectious disease research. Public and philanthropic investment... | 25,162,631 | [
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Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. | Asymptomatic primary hyperparathyroidism (PHPT) is routinely encountered in clinical practices of endocrinology throughout the world. This report distills an update of current information about diagnostics, clinical features, and management of this disease into a set of revised guidelines. Participants, representing an... | 25,162,665 | [
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Does primary care mental health resourcing affect the use and costs of secondary psychiatric services? | Collaborative care models for treatment of depression and anxiety disorders in primary care have been shown to be effective. The aim of this study was to investigate at the municipal level to what extent investment in mental health personnel at primary care health centres in the study area is reflected in the costs and... | 25,162,710 | [
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A refined technique to calculate finite helical axes from rigid body trackers. | Finite helical axes (FHAs) are a potentially effective tool for joint kinematic analysis. Unfortunately, no straightforward guidelines exist for calculating accurate FHAs using prepackaged six degree-of-freedom (6 DOF) rigid body trackers. Thus, this study aimed to: (1) describe a protocol for calculating FHA parameter... | 25,162,715 | [
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Evaluation of tensile retention of Y-TZP crowns cemented on resin composite cores: effect of the cement and Y-TZP surface conditioning. | This study evaluated the effect of the cement type (adhesive resin, self-adhesive, glass ionomer, and zinc phosphate) on the retention of crowns made of yttria-stabilized polycrystalline tetragonal zirconia (Y-TZP). Therefore, 108 freshly extracted molars were embedded in acrylic resin, perpendicular to their long axis... | 25,162,722 | [
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Multiple intrinsically identical single-photon emitters in the solid state. | Emitters of indistinguishable single photons are crucial for the growing field of quantum technologies. To realize scalability and increase the complexity of quantum optics technologies, multiple independent yet identical single-photon emitters are required. However, typical solid-state single-photon sources are inhere... | 25,162,729 | [
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Physicochemical properties of some bottled water brands in Alexandria Governorate, Egypt. | Many people use bottled water instead of tap water for many reasons such as taste, ease of carrying, and thinking that it is safer than tap water. Irrespective of the reason, bottled water consumption has been steadily growing in the world for the past 30 years. In Egypt, this is still increasing to reach 3.8 l/person/... | 25,162,736 | [
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Skin deposition and permeation of finasteride in vitro: effects of propylene glycol, ethanol and sodium lauryl sulfate. | The objective of this study was to investigate the effects of propylene glycol (PG), ethanol (EtOH) and sodium lauryl sulfate (SLS) on the in vitro deposition and permeation of finasteride (FNS). A side-by-side diffusion cell mounted with a pig ear skin and a saturated solution of FNS in PG (10, 20% v/v), EtOH (10, 20%... | 25,162,771 | [
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Healthcare costs for Crohn's disease patients treated with infliximab: a propensity weighted comparison of the effects of treatment adherence. | The objective for the research was to evaluate the direct healthcare costs for Crohn's disease (CD) patients categorized by adherence status. Adult patients with ≥1 claim for infliximab and ≥2 claims for CD who were continuously insured for 12 months before and after their first infliximab infusion (index date) were id... | 25,162,777 | [
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The impact of vulvar lichen sclerosus on sexual dysfunction. | Lichen sclerosus (LS) is a chronic inflammatory condition that is known to arise on the vulva. Many women with LS report vulvar pain, often affecting a patient's quality of life. In this study, the sexual function of LS patients, with and without pain, was compared to control populations. A case-control study to examin... | 25,162,790 | [
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Influence of transportation cost on long-term retention in clinic for HIV patients in rural Haiti. | With improved access to antiretroviral therapy in resource-constrained settings, long-term retention in HIV clinics has become an important means of reducing costs and improving outcomes. Published data on retention in HIV clinics beyond 24 months are, however, limited. In our clinic in rural Haiti, we hypothesized tha... | 25,162,815 | [
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Raltegravir pharmacokinetics during pregnancy. | We evaluated the pharmacokinetics (PK) of raltegravir in HIV-infected women during pregnancy and postpartum. International Maternal Pediatric Adolescent AIDS Clinical Trials 1026s is an ongoing prospective study of antiretroviral PK during pregnancy (NCT00042289). Women receiving 400 mg raltegravir twice daily in combi... | 25,162,818 | [
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Treatment of severe chronic graft-versus-host disease with decidual stromal cells and tracing with (111)indium radiolabeling. | Decidual stromal cells (DSCs) isolated from fetal membranes of term placentas are easily expanded and are highly immunosuppressive in vitro. These cells express high levels of integrins that are of importance in homing to inflamed tissues. In this study, we investigated DSCs as a cellular therapy for chronic graft-vers... | 25,162,829 | [
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Aluminum triflate catalyzed tandem reactions of D-galactal: toward chiral benzopyrans, chromenes, and chromans. | 3,4,6-Tri-O-acetyl-D-galactal is selectively converted into 1-O-aryl-2-deoxy derivatives or chiral bridged benzopyrans under Al(OTf)3 catalysis, depending on reaction conditions. The benzopyrans react with Al(OTf)3/acetic anhydride in ring-opening reactions in the absence or presence of acetic acid to selectively produ... | 25,162,834 | [
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Separation from supported employment: a retrospective chart review study. | The objective of this study was to examine job separations from supported employment (SE). The aim was to identify the types and nature of separations and precipitating events leading to the separation. A retrospective chart review methodology was utilized. The study was conducted in a metropolitan area in the Southeas... | 25,162,839 | [
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Suicide terrorism and post-mortem benefits. | Lankford claims that suicide terrorists are suicidal, but that their suicidal tendencies are often frustrated by injunctive social norms. Martyrdom represents a solution, and terrorist organizations exploit this. In this commentary, we claim that this argument has not been fully made and that such ideation in itself do... | 25,162,847 | [
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Large-scale societal changes and intentionality - an uneasy marriage. | Our commentary focuses on juxtaposing the proposed science of intentional change with facts and concepts pertaining to the level of large populations or changes on a worldwide scale. Although we find a unified evolutionary theory promising, we think that long-term and large-scale, scientifically guided - that is, inten... | 25,162,863 | [
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Evolutionary processes and mother-child attachment in intentional change. | Behavioral change may occur through evolutionary processes such as running stochastic evolutionary algorithms, with a fitness function to determine a winning solution from many. A science of intentional change will therefore require identification of fitness functions - causal mechanisms of adaptation - that can be acq... | 25,162,871 | [
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Domain-general mechanisms: what they are, how they evolved, and how they interact with modular, domain-specific mechanisms to enable cohesive human groups. | Domain-general mechanisms are evolutionarily ancient, resulting from the evolution of affective cues signaling the attainment of evolutionary goals. Explicit processing is a particularly important set of domain-general mechanisms for constructing human groups - enabling ideologies specifying future goal states and rati... | 25,162,875 | [
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Conservation combats exploitation: choices within an evolutionary framework. | Intentional change when viewed as making a risky or intertemporal choice with evolutionary relevance helps us understand its successes and its failures. To promote future-oriented ecological rationality requires establishing a linkage between nongenetic, cultural, and symbolic selections and genetic adaptations. Couple... | 25,162,882 | [
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Automated classification of optical coherence tomography images for the diagnosis of oral malignancy in the hamster cheek pouch. | Most studies evaluating the potential of optical coherence tomography (OCT) for the diagnosis of oral cancer are based on visual assessment of OCT B-scans by trained experts. Human interpretation of the large pool of data acquired by modern high-speed OCT systems, however, can be cumbersome and extremely time consuming... | 25,162,909 | [
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Biomechanics of the canine mandible during bone transport distraction osteogenesis. | This study compared biomechanical patterns between finite element models (FEMs) and a fresh dog mandible tested under molar and incisal physiological loads in order to clarify the effect of the bone transport distraction osteogenesis (BTDO) surgical process. Three FEMs of dog mandibles were built in order to evaluate t... | 25,162,918 | [
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Pruritus in pediatric burn survivors: defining the clinical course. | Pruritus is a frequent and severe symptom and a significant cause of distress for adult burn patients. Its effects in children are largely unstudied. The aim of this study is to characterize postburn itch in the pediatric population. This is a retrospective review from 2006 to 2013 for pediatric burn survivors who were... | 25,162,949 | [
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Synthesis and cytotoxic evaluation of a series of 2-amino-naphthoquinones against human cancer cells. | The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 (ovarian), NCI-H358M (bronchoalveolar lung carcinoma) and PC3-M (prosta... | 25,162,959 | [
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Adverse events, length of stay, and readmission after surgery for tibial plateau fractures. | To identify factors that are associated with short-term outcomes after open reduction and internal fixation (ORIF) for tibial plateau fracture. Patients who underwent ORIF for tibial plateau fracture from 2009 to 2012 were identified in the American College of Surgeons National Surgical Quality Improvement Program data... | 25,162,975 | [
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Patient characteristics upon initial presentation to chiropractic teaching clinics: A descriptive study conducted at one university. | Objective : The purpose of this study was to compare demographics and chief complaints of the new patient population at our institution's fee-for-service clinics to the patient population of practicing chiropractors in the United States. We also compared the prevalence of obesity and hypertension to reference standards... | 25,162,982 | [
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Heterogeneous vascular responses to lifestyle intervention in obese Latino adolescents. | Among adolescents, obesity may increase the risk for premature cardiovascular disease (CVD). Lifestyle interventions may prevent or delay the onset of CVD through improvements in vascular health. The purpose of this study was to examine the effects of a 12-week lifestyle intervention on markers of vascular health in ob... | 25,162,989 | [
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Activators of AMPK: not just for type II diabetes. | Recent discoveries of AMPK activators point to the large number of therapeutic candidates that can be transformed to successful designs of novel drugs. AMPK is a universal energy sensor and influences almost all physiological processes in the cells. Thus, regulation of the cellular energy metabolism can be achieved in ... | 25,163,002 | [
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Overexpression of the HspL Promotes Agrobacterium tumefaciens Virulence in Arabidopsis Under Heat Shock Conditions. | Agrobacterium tumefaciens transfers a specific DNA fragment from the resident tumor-inducing (Ti) plasmid and effector virulence (Vir) proteins to plant cells during infection. A. tumefaciens VirB1-11 and VirD4 proteins assemble as the type IV secretion system (T4SS), which mediates transfer of the T-DNA and effector V... | 25,163,013 | [
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Migraine in students of a US medical school. | The study's aim was to determine migraine prevalence, severity, and educational impact in medical students. A 23-item survey of all medical students of one US medical school addressed migraine frequency, triggers, pattern and severity of symptoms, medication use, impact on educational activities and career choices. The... | 25,163,040 | [
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Early Index for Detection of Pediatric Emergency Department Crowding. | When epidemics occur, such as is the case for bronchiolitis in the Pediatric Emergency Department (ED), the patient flow in the ED incontestably increases and can lead to crowding. We bypassed this difficulty of forecasting patient flow with aggregated weekly or monthly data by tackling the problem from a different poi... | 25,163,075 | [
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Biomarkers of cerebral injury in cardiac surgery. | The present study aims to reveal the changing patterns of cerebral biomarkers and the underlying predictive factors as a consequence of cardiac surgery. Literature retrieval of articles on S100 and S100B of recent 20 years were made in the MEDLINE database, Highwire Press and Google search. Quantitative data of S100 an... | 25,163,078 | [
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Grass invasion increases top-down pressure on an amphibian via structurally mediated effects on an intraguild predator. | Plants serve as both basal resources and ecosystem engineers, so plant invasion may exert trophic influences on consumers both via bottom-up processes and by altering the environmental context in which trophic interactions occur. To determine how these mechanisms affect a native predator we used a mark-recapture study ... | 25,163,106 | [
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Granivory of invasive, naturalized, and native plants in communities differentially susceptible to invasion. | Seed predation is an important biotic filter that can influence abundance and spatial distributions of native species through differential effects on recruitment. This filter may also influence the relative abundance of nonnative plants within habitats and the communities' susceptibility to invasion via differences in ... | 25,163,110 | [
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Ephemeral disturbances have long-lasting impacts on forest invasion dynamics. | Ephemeral disturbances are common in many systems. Often, these brief events are assumed to be a nuisance with little long-term ecological impact. We quantified the impact of the ephemeral forest disturbance caused by gypsy moth canopy defoliation on exotic plant invasion in eight hardwood forests in the Delaware Water... | 25,163,111 | [
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Context-dependent effects of nutrient loading on the coral-algal mutualism. | Human-mediated increases in nutrient availability alter patterns of primary production, impact species diversity, and threaten ecosystem function. Nutrients can also alter community structure by disrupting the relationships between nutrient-sharing mutualists that form the foundation of communities. Given their oligotr... | 25,163,130 | [
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Public-private interactions in global food safety governance. | In response to an apparent decline in global food safety, numerous public and private regulatory initiatives have emerged to restore public confidence. This trend has been particularly marked by the growing influence of private regulators such as multinational food companies, supermarket chains and non-governmental org... | 25,163,209 | [
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Origins of the prohibition against off-label promotion. | The statute and regulations administered by the Food and Drug Administration ("FDA") do not explicitly prohibit the promotion of drugs and medical devices for unapproved uses, yet the government has collected billions of dollars in penalties for such "off-label" promotion. The statutory interpretations and regulatory p... | 25,163,210 | [
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The influence of patronage nurses on breastfeeding. | The aim of this review was to estimate the influence of patronage nurses on breastfeeding. A retrospective research was conducted in the form of telephone questionnaire on a total of 25 subjects. Eighteen (72%) mothers had previous experience with breastfeeding, while 7 (28%) had no such experience. In 18 (72%) mothers... | 25,163,236 | [
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[Effect of new oral antimicrobial agents in outpatient treatment of pneumonia in children]. | In November 2004, "Guidelines for the Management of Respiratory Infectious Diseases in Children in Japan" was published ahead of the rest of the world, by Japanese Society of Pediatric Pulmonology/Japanese Society for Pediatric Infectious Diseases, based on the data on causative organisms in the lower respiratory tract... | 25,163,249 | [
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[Plasminogen activation and regulation of fibrinolysis]. | Plasminogen activator-plasmin system is the central role for thrombus degradation. The system is finely tuned to allow healing of a blood vessel lesion without compromising the stability of the fibrin thrombus, and to localize fibrinolytic activity to the damaged area. There is a dynamic balance between fibrinolytic fa... | 25,163,311 | [
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[Cardiac graft allocation]. | Until 2004, French rules for cardiac graft allocation were aimed at ensuring uniform organ distribution on the national scale, while logically giving priority to local teams. The allocation was center-based, with transplant MDs choosing the most suitable recipient from the local waiting list. In 2004, two national prio... | 25,163,343 | [
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[A 25-year study (1983-2008) of children's health outcomes after hyperbaric oxygen therapy for carbon monoxide poisoning in utero]. | Carbon monoxide (CO) poisoning during pregnancy can be fatal for the fetus, or cause bone malformations or encephalopathy, depending on the stage of pregnancy at which the poisoning occurs. Fewer cases of death and encephalopathy have been reported since the adoption of maternal hyperbaric oxygen (HBO) therapy in this ... | 25,163,349 | [
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Carybdea marsupialis (Cubozoa) in the Mediterranean Sea: the first case of a sting causing cutaneous and systemic manifestations. | A woman stung by the box jellyfish Carybdea marsupialis (Cnidaria, Cubozoa) at a Spanish Mediterranean beach showed systemic manifestations over several months [pain far from the inoculation point, arthralgia, paresthesia, hyperesthesia, increase in eosinophils and immunoglobulin E (IgE)] in addition to the skin condit... | 25,163,356 | [
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Content analysis of Australian direct-to-consumer websites for emerging breast cancer imaging devices. | To describe the nature and frequency of information presented on direct-to-consumer websites for emerging breast cancer imaging devices. Content analysis of Australian website advertisements from 2 March 2011 to 30 March 2012, for three emerging breast cancer imaging devices: digital infrared thermal imaging, electrica... | 25,163,383 | [
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Dimensional analysis yields the general second-order differential equation underlying many natural phenomena: the mathematical properties of a phenomenon's data plot then specify a unique differential equation for it. | This study uses dimensional analysis to derive the general second-order differential equation that underlies numerous physical and natural phenomena described by common mathematical functions. It eschews assumptions about empirical constants and mechanisms. It relies only on the data plot's mathematical properties to p... | 25,163,387 | [
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Structures affecting recovery of macular function in patients with age-related macular degeneration after intravitreal ranibizumab. | To determine the retinal structures affecting the recovery of macular function in patients with exudative age-related macular degeneration (AMD) treated with intravitreal ranibizumab (IVR). Thirty eyes of 30 patients with exudative AMD who were treated with IVR at monthly intervals for 3 months were studied. Focal macu... | 25,163,415 | [
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Do cities simulate climate change? A comparison of herbivore response to urban and global warming. | Cities experience elevated temperature, CO2 , and nitrogen deposition decades ahead of the global average, such that biological response to urbanization may predict response to future climate change. This hypothesis remains untested due to a lack of complementary urban and long-term observations. Here, we examine the r... | 25,163,424 | [
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Xylem sap in cotton contains proteins that contribute to environmental stress response and cell wall development. | The xylem sap of a plant is primarily responsible for transporting molecules from the underground root system to the aboveground parts of the plant body. In order to understand the role that roots play in cotton growth and development, the components present in xylem sap must be elucidated. In this study, we used a sho... | 25,163,431 | [
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Model drug as pore former for controlled release of water-soluble metoprolol succinate from ethylcellulose-coated pellets without lag phase: opportunities and challenges. | The objective of the present study was to evaluate the feasibility of using model drug metoprolol succinate (MS) as a pore former to modify the initial lag phase (i.e., a slow or non-release phase in the first 1-2 h) associated with the drug release from coated pellets. MS-layered cores with high drug-layering efficien... | 25,163,432 | [
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Primary stabbing headache in adults and pediatrics: a review. | Primary stabbing headache (PSH) is an under-recognized primary headache disorder, which often goes undiagnosed. It is mainly characterized by its ultrashort stabbing quality and can be easily overlooked both by patients and providers as it is often not severe enough to interfere significantly with daily life. However, ... | 25,163,436 | [
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Sufficiency and necessity in migraine: how do we figure out if triggers are absolute or partial and, if partial, additive or potentiating? | Migraine is, to a great extent, a genetically determined disorder and once it has manifested itself, it generally continues for years if not for decades. While the migraine is active, headaches can seemingly occur spontaneously but are often reportedly precipitated by events or factors, known as migraine triggers, the ... | 25,163,437 | [
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The rules of information aggregation and emergence of collective intelligent behavior. | Information is a peculiar quantity. Unlike matter and energy, which are conserved by the laws of physics, the aggregation of knowledge from many sources can in fact produce more information (synergy) or less (redundancy) than the sum of its parts. This feature can endow groups with problem-solving strategies that are s... | 25,163,449 | [
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Oral toxicity evaluation of thiodiglycol in Sprague-Dawley rats. | Thiodiglycol (TDG) is the main product of sulfur mustard hydrolysis and is an environmental contaminant. Subacute and subchronic oral toxicity studies with TDG were conducted in Sprague-Dawley rats. Neat TDG was administered by gavage at doses of 157, 313, 625, 1250, 2500, 5000, and 9999 mg/kg/d, 5 days per week, for 1... | 25,163,473 | [
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Human extravillous trophoblast invasion: intrinsic and extrinsic regulation. | During the establishment of pregnancy, a human blastocyst implants into the uterine endometrium to facilitate the formation of a functional placenta. Implantation involves the blastocyst adhering to the uterine luminal epithelium before the primitive syncytiotrophoblast and subsequently specialised cells, the extravill... | 25,163,485 | [
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A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence. | The polysaccharide capsule is a major virulence factor of the important human pathogen Streptococcus pneumoniae. However, S. pneumoniae strains lacking capsule do occur. Here, we report a nasopharyngeal isolate of Streptococcus pneumoniae composed of a mixture of two phenotypes; one encapsulated (serotype 18C) and the ... | 25,163,487 | [
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Direct in vivo electrochemical detection of haemoglobin in red blood cells. | The electrochemical behavior of iron ion in haemoglobin provides insight to the chemical activity in the red blood cell which is important in the field of hematology. Herein, the detection of haemoglobin in human red blood cells on glassy carbon electrode (GC) was demonstrated. Red blood cells or raw blood cells was im... | 25,163,492 | [
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Clinicopathologial features of gastric hepatoid adenocarcinoma. | Gastric hepatoid adenocarcinoma (GHA), a rare type of primary gastric cancer, is characterized by hepatocellular carcinoma-like histology. As details of this disease remain unknown, the aim of this study was to evaluate the clinicopathological features of GHA. From January 2001 to December 2010, 4563 patients were diag... | 25,163,499 | [
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HLA-G in human early pregnancy: control of uterine immune cell activation and likely vascular remodeling. | Despite a number of controversies, the functional importance of human leukocyte antigen G (HLA-G) in early human pregnancy is now sustained by a large amount of sound data. Membrane-bound and soluble HLA-G isoforms, either as β2-microglobulin-free or -associated as monomers or dimers, are expressed by different trophob... | 25,163,504 | [
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Endothelial-mesenchymal transition in normal human esophageal endothelial cells cocultured with esophageal adenocarcinoma cells: role of IL-1β and TGF-β2. | Endothelial-mesenchymal transition (EndoMT) has been recognized as a key determinant of tumor microenvironment in cancer progression and metastasis. Endothelial cells undergoing EndoMT lose their endothelial markers, acquire the mesenchymal phenotype, and become more invasive with increased migratory abilities. Early s... | 25,163,519 | [
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First report on two-fold classification of Plasmodium falciparum carbonic anhydrase inhibitors using QSAR modeling approaches. | Quantitative structure-activity relationship (QSAR)-based classification approach is one of the important chemometric tools in drug discovery process for categorizing the target protein inhibitors into more active and less active classes. In this background, we have presented here a novel approach of two-fold QSAR-base... | 25,163,527 | [
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Sources of perceived social support associated with reduced psychological distress at 1 year after the Great East Japan Earthquake: Nationwide cross-sectional survey in 2012. | Lack of social support has been associated with a higher level of psychological distress after disasters, but its relative associations with sources of support such as neighbors, friends, family, and others, are underreported. The present study assessed the associations of social support with psychological distress acc... | 25,163,533 | [
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Factors affecting the accumulation of perfluoroalkyl substances in human blood. | The aim of this study is to evaluate the presence of perfluoroalkyl substances (PFASs) in the blood of 46 residents from Barcelona and to study the factors that affect exposure. Compounds analysed included perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), perfluorobutane sulfonate (PFBS), perfluorooc... | 25,163,560 | [
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0.4666187,
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Characterization of bacteria isolated from palaeoproterozoic metasediments for sequestration of carbon dioxide and formation of calcium carbonate. | Bacterial community of palaeoproterozoic metasediments was enriched in the chemostat in the presence of different concentrations of NaHCO3. Six bacterial isolates were isolated from the chemostat on nutrient agar plates on the basis of distinct morphology. Denaturing gradient gel electrophoresis (DGGE) proved the prese... | 25,163,561 | [
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Toxicity of sediment cores from Yangtze River estuary to zebrafish (Danio rerio) embryos. | Toxicity evaluation is an important segment in sediment quality monitoring in order to protect aquatic organisms and human health. The purpose of this study is to assess the toxicity of sediments from three sediment cores in Yangtze River Estuary, China, using the zebrafish (Danio rerio) embryo tests. Fertilized zebraf... | 25,163,567 | [
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0.08300231,
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0.1170259,
0.181517,
0.04880893,
-0.4410228,
0.4294195,
0.1719009,
0.2686021,
0.06850983,
0.6704281,
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Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103). | Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome have often been excluded from myeloablative-conditioning regimens containing busulfan because of non-disease-related morbidity and mortality. We hypothesized that busulfan clearance (BuCL) in older patients (>60 years) would be reduced com... | 25,163,570 | [
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[Pollen dispersion of cryptmeria japonica in the autumn at the Oita University Faculty of Medicine Complex]. | It has been reported that Japanese cedar pollinosis patients develop symptoms in the autumn. We investigated the atmospheric Japanese cedar pollen dispersion in the autumn at the Oita University Faculty of Medicine Complex. We set up a Durham sampler on the roof (30 m from the ground) of the Oita University Faculty of ... | 25,163,578 | [
-0.06290051,
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0.2093771,
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The evaluation of Zataria multiflora Boiss. essential oil effect on biogenic amines formation and microbiological profile in Gouda cheese. | The effect of Zataria multiflora Boiss. (Z. multiflora) essential oils (EO) on biogenic amines (BAs) production and microbial counts in Gouda cheese has been investigated. Zataria multiflora was added to milk in different concentrations (0·05, 0·1, 0·2 and 0·4% (v/v)). The BAs (tyramine and histamine) were measured by ... | 25,163,583 | [
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0.2119792,
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Systematic Epstein-Barr virus-positive T-cell lymphoproliferative disease presenting as a persistent fever and cough: a case report. | Systemic Epstein-Barr virus-positive T-cell lymphoproliferative childhood disease is an extremely rare disorder and classically arises following primary acute or chronic active Epstein-Barr virus infection. It is characterized by clonal proliferation of Epstein-Barr virus-infected T-cells with an activated cytotoxic ph... | 25,163,591 | [
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Prevalence of neutralising antibodies against adenoviruses in lizards and snakes. | Adenoviruses (AdVs) are relatively common in lizards and snakes, and several genetically distinct AdVs have been isolated in cell culture. The aims of this study were to examine serological relationships among lizard and snake AdVs and to determine the frequency of AdV infections in these species. Isolates from a boa c... | 25,163,614 | [
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0.2582541,
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... |
Controlling a robot with intention derived from motion. | We present a novel, sophisticated intention-based control system for a mobile robot built from an extremely inexpensive webcam and radio-controlled toy vehicle. The system visually observes humans participating in various playground games and infers their goals and intentions through analyzing their spatiotemporal acti... | 25,163,625 | [
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0.05049453,
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Use of a vacuum-assisted closure system for the management of enteroatmospheric fistulae. | The aim of this study was to analyze the management of enteroatmospheric fistulae (EAF) in an open abdomen using vacuum-assisted closure (VAC) therapy. Eighteen patients (ten male/eight female) were treated in our surgical department for the management of EAF. VAC therapy was used to manage both complex and open abdomi... | 25,163,660 | [
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Utilization of by-products derived from bioethanol production process for cost-effective production of lactic acid. | The by-products of bioethanol production such as thin stillage (TS) and condensed distillers solubles (CDS) were used as a potential nitrogen source for economical production of lactic acid. The effect of those by-products and their concentrations on lactic acid fermentation were investigated using Lactobacillus paraca... | 25,163,666 | [
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... |
Noise in hospital rooms and sleep disturbance in hospitalized medical patients. | Hospitalized patients are vulnerable to sleep disturbances because of environmental stresses including noise. While most previous studies on hospital noise and sleep have been performed for medical machines in intensive care units, there is a limited data for patients hospitalized in medical wardrooms. The purpose of p... | 25,163,680 | [
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0.2522473,
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Impact of RNA-guided technologies for target identification and deconvolution. | For well over a decade, RNA interference (RNAi) has provided a powerful tool for investigators to query specific gene targets in an easily modulated loss-of-function setting, both in vitro and in vivo. Hundreds of publications have demonstrated the utility of RNAi in arrayed and pooled-based formats, in a wide variety ... | 25,163,683 | [
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... |
Calcyclin-binding protein/Siah-1-interacting protein as a regulator of transcriptional responses in brain cells. | The calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP) is highly expressed in the brain and has been shown to regulate β-catenin-driven transcription in thymocytes. Therefore, we investigated whether CacyBP/SIP plays a role as a transcriptional regulator in brain cells. In brain-derived neurotrophic fact... | 25,163,685 | [
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0.06108268,
0.4259297,
0.002120178,
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The influence of relative body breadth on the diaphyseal morphology of the human lower limb. | Variation in relative body breadth between individuals is potentially a significant influence on the biomechanical loading placed upon the lower limb. This study investigates the influence of relative body breadth on the periosteal geometry of the diaphyses of the limb bones among individuals from a broad range of huma... | 25,163,696 | [
0.06024083,
0.2045715,
0.07097522,
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0.2047287,
0.3620931,
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Biomarkers for radiographic progression in rheumatoid arthritis. | Treatment of patients with rheumatoid arthritis (RA) is rarely personalized, since predictors of disease course are lacking. The severity of RA can be measured objectively by radiographic progression. The most reliable way to measure radiographic progression is in a longitudinal cohort with serial time points, scoring ... | 25,163,742 | [
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0.05914558,
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0.5650377,
0.06561928,
0.274689,
-0.46879,
-0.13... |
Effects of a single course versus repeated courses of antenatal corticosteroids on fetal growth, placental morphometry and the differential regulation of vascular endothelial growth factor. | To investigate the impact of antenatal exposure to a single course or repeated courses of dexamethasone (DEX) on neonatal anthropometrics, placental morphometry and potential effect on maternal plasma levels and placental expression of vascular endothelial growth factor (VEGF). Pregnant women between 27 and 32 weeks of... | 25,163,747 | [
0.110996,
0.05026464,
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0.6776617,
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0.2098048,
0.04624087,
0.1074366,
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0.4290299,
-0.08824182... |
Non-steroidal anti-inflammatory drug use in chronic pain conditions with special emphasis on the elderly and patients with relevant comorbidities: management and mitigation of risks and adverse effects. | Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most frequently used drugs, and this widespread use is complicated by safety issues. A Literature review was conducted. NSAIDs are a leading cause of drug-related morbidity, especially in the elderly and patients with comorbidities. Most adverse effects are r... | 25,163,793 | [
-0.3815675,
0.0733494,
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0.03327633,
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0.1847306,
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0.002630783,
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0.1382642,
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... |
Modulation of stem cell differentiation by the influence of nanobiomaterials/carriers. | Stem cells, either neural [NSCs] or mesenchymal [MSCs], possess tremendous untapped potential for cell therapy. Unlike the NSCs, MSCs are multi-potent and they have high self-renewal capability and broad tissue distribution. Since they do not produce significant immune rejection on post-transplantation; they are better... | 25,163,795 | [
0.05964054,
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0.1630222,
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0.01482933,
0.110891,
0.1096395,
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Triplet sensitized photolysis of a vinyl azide: direct detection of a triplet vinyl azide and nitrene. | Photolysis of vinylazide 1, which has a built-in acetophenone triplet sensitizer, in argon-saturated toluene results in azirine 2, whereas irradiation in oxygen-saturated toluene yields cyanide derivatives 3 and 4. Laser flash photolysis of azide 1 in argon-saturated acetonitrile shows formation of vinylnitrene 1c, whi... | 25,163,813 | [
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0.2070971,
0.1739456,
0.21717,
0.3442493,
0.2438515,
-0.1166003,
0.08... |
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