title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Role of microbiological factors in predicting early childhood caries. | Microbiological methods that accurately identify caries-susceptible children may enhance caries control and assist treatment planning. This study's purpose was to evaluate the usefulness of two microbiological indicators (mutans streptococci [MS] and lactobacilli [LB] levels), singly and in combination, for predicting ... | 25,198,002 | [
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Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. | Autism spectrum disorders (ASDs) are complex and heterogeneous developmental disabilities affecting an ever-increasing number of children worldwide. The diverse manifestations and complex, largely genetic aetiology of ASDs pose a major challenge to the identification of unifying neuropathological features. Here we desc... | 25,198,012 | [
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Respiratory epithelial adenomatoid hamartoma of the nose: an updated review. | This study was designed to update clinical and imaging features as well as treatment outcomes of the nasal respiratory epithelial adenomatoid hamartoma (REAH). Data sources included case reports, original articles, and reviews published in English or French in PubMed from 1995 to date. Only published articles that met ... | 25,198,016 | [
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Analysis of a database to predict the result of allergy testing in vivo in patients with chronic nasal symptoms. | This article uses the logistic regression model for diagnostic decision making in patients with chronic nasal symptoms. We studied the ability of the logistic regression model, obtained by the evaluation of a database, to detect patients with positive allergy skin-prick test (SPT) and patients with negative SPT. The mo... | 25,198,028 | [
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Enhanced photoelectrochemical water splitting performance of anodic TiO(2) nanotube arrays by surface passivation. | One-dimensional anodic titanium oxide nanotube (TONT) arrays provide a direct pathway for charge transport, and thus hold great potential as working electrodes for electrochemical energy conversion and storage devices. However, the prominent surface recombination due to the large amount surface defects hinders the perf... | 25,198,058 | [
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The burden of youth: major traumatic injury in adolescents and young adults managed in the Australian Capital Territory. | To determine the incidence, characteristics, and factors associated with mortality after major traumatic injury in adolescent and young people in the Australian Capital Territory (ACT). A combined retrospective analysis of the National Coroners Information System and ACT Level 1 Trauma Centre registry data from July 20... | 25,198,076 | [
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Benefits of medication therapy management in trauma care. | Recently, medication therapy management has gained significant momentum, which has largely been fueled the desire to optimize patients' medication treatment. The implementation of medication therapy management is proving to be increasingly important in trauma care because of a myriad of issues whether cognitive, mental... | 25,198,077 | [
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[Capsule endoscopy in a supra-regional network corporation: experience in more than 1000 cases]. | Capsule endoscopy (CE) is firmly established as a standard procedure in the diagnostic algorithm of mid gastrointestinal (GI) bleeding. Despite its excellent diagnostic yield, missing expertise, reading time and financial expenditure limit an area-wide availability. A multicentric cooperation might compensate these dis... | 25,198,086 | [
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The power of presence: the role of mindfulness at work for daily levels and change trajectories of psychological detachment and sleep quality. | In this research, we examined the role of mindfulness for recovery from work using a daily diary design (N = 121; 5 days; 3 measurement occasions per day). The first goal of the study was to investigate the relationship of mindfulness with sleep quality and the mediating role of psychological detachment from a day-leve... | 25,198,098 | [
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An expanded delivery model for outpatient burn rehabilitation. | Despite the numerous multidisciplinary services burn centers provide, a number of challenges to obtaining optimal outcomes exist. The goal of this study was to overcome the barriers to effective burn rehabilitation by utilizing an expanded care coordinator (ECC) to supplement the existing outpatient services. In this b... | 25,198,101 | [
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Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma. | The human forkhead box A1 (FOXA1) and A2 (FOXA2) transcription factors have been found to control estrogen and androgen signaling through co-regulating target genes with sex hormone receptors. Here we used an integrative strategy to examine the hypothesis that genetic variants at FOXA1/2 binding elements may be associa... | 25,198,130 | [
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Early exposure of dams to a westernized diet has long-term consequences on food intake and physiometabolic homeostasis of the rat offspring. | This study evaluated the long-term effects of a westernized diet during pregnancy and lactation. Female Wistar rats (n = 12) were divided into two groups according to their food intake, namely, control (C) or westernized (W) diet, throughout pregnancy/lactation. On the 21st day, the male pups were weaned on a standard ... | 25,198,159 | [
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Trends in Alcoholic Hepatitis-related Hospitalizations, Financial Burden, and Mortality in the United States. | Alcoholic hepatitis (AH) is the most florid manifestation of alcoholic liver disease which accounts for significant morbidity, mortality, and financial burden. Aim of this study is to evaluate temporal trend of hospitalizations from AH and evaluate its financial impact. The National Inpatient Sample databases (from 200... | 25,198,164 | [
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Freezing-induced ordering of block copolymer micelles. | We demonstrate here the ordering of block copolymer micelles by ice templating, below 0 °C. We used this for the preparation of silica monoliths that present an ice-templated macroporosity, combined with a 2D hexagonal mesostructure templated by the addition of P123. We propose a mechanism triggered by the progressive ... | 25,198,174 | [
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Multilocus sequence analysis for assessment of phylogenetic diversity and biogeography in Thalassospira bacteria from diverse marine environments. | Thalassospira bacteria are widespread and have been isolated from various marine environments. Less is known about their genetic diversity and biogeography, as well as their role in marine environments, many of them cannot be discriminated merely using the 16S rRNA gene. To address these issues, in this report, the phy... | 25,198,177 | [
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Effect of heat stress soon after muscle injury on the expression of MyoD and myogenin during regeneration process. | Heat stress could promote skeletal muscle regeneration. But, in the regeneration process, effects of heat stress on myogenic cells and the regulating factors is unknown. Therefore, Influences of heat stress soon after injury on distribution of the myogenic cells and chronological changes in expression of MyoD and myoge... | 25,198,228 | [
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Screening for characteristic genes in osteoarthritis induced by destabilization of the medial meniscus utilizing bioinformatics approach. | To explore the underlying molecular mechanism of the development of OA (osteoarthritis). The expression profile dataset GSE26475 was downloaded from Gene Expression Omnibus database. A total of 21 samples were available, including knee joint samples from OA mice induced by DMM (Destabilization of the medial meniscus) s... | 25,198,230 | [
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Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases. | The correct establishment and maintenance of DNA methylation patterns are critical for mammalian development and the control of normal cell growth and differentiation. DNA methylation has profound effects on the mammalian genome, including transcriptional repression, modulation of chromatin structure, X chromosome inac... | 25,198,254 | [
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Dietary folate and reproductive success among women undergoing assisted reproduction. | To prospectively evaluate the associations of folate with assisted reproductive technology outcomes within a population in the United States. This analysis included women (n=232) in a prospective cohort study at the Massachusetts General Hospital Fertility Center. Diet was assessed before assisted reproductive technolo... | 25,198,264 | [
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Cesarean delivery times and adhesion severity associated with prior placement of a sodium hyaluronate-carboxycellulose barrier. | To evaluate the association between the prior use of a sodium hyaluronate-carboxycellulose adhesion barrier and the incision-to-delivery time and adhesion scores at first repeat cesarean delivery. In this cohort study, intraoperative data were prospectively collected at the time of the study participants' first repeat ... | 25,198,272 | [
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Clinical risk factors for preeclampsia in the 21st century. | We sought to validate several clinical risk factors previously described for preeclampsia in a large contemporary multicenter prospective cohort. We enrolled women from three sites before 15 weeks of gestation. Demographic and clinical risk factors were collected through standardized chart review. The main outcome of p... | 25,198,274 | [
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Treatment of vaginal cuff evisceration. | Laparoscopic and robotic-assisted hysterectomies are associated with higher rates of vaginal cuff dehiscence and evisceration than are open and vaginal hysterectomies. With the rising prevalence of minimally invasive hysterectomy, gynecologists should know how to manage this rare but potentially serious condition. Urge... | 25,198,277 | [
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Umbilical cord arterial lactate compared with pH for predicting neonatal morbidity at term. | To test the hypothesis that umbilical cord arterial lactate is superior to pH for predicting short-term neonatal morbidity at term. We conducted a prospective cohort study of all consecutive, non-anomalous, singleton, vertex, term births from 2009 to 2012 at Washington University Medical Center. Umbilical arterial lact... | 25,198,278 | [
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Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia. | Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder, caused by a GAA repeat expansion mutation within intron 1 of the FXN gene. We have previously established and performed preliminary characterisation of several human FXN yeast artificial chromosome (YAC) transgenic FRDA mouse models containi... | 25,198,290 | [
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Anionic N-heterocyclic carbenes (NHCs): a versatile route to saturated NHCs bearing pendant weakly coordinating anions. | A versatile methodology is reported for the synthesis of anionic NHCs featuring a 5-, 6-, or 7-membered saturated heterocyclic core. Lewis acid promoted exocyclic ring closure generates systems in which the pendant borate functionality is incorporated via a CH2 linker, allowing for electronic and steric isolation of th... | 25,198,297 | [
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Setting a good example: supervisors as work-life-friendly role models within the context of boundary management. | This multisource, multilevel study examined the importance of supervisors as work-life-friendly role models for employees' boundary management. Particularly, we tested whether supervisors' work-home segmentation behavior represents work-life-friendly role modeling for their employees. Furthermore, we tested whether wor... | 25,198,308 | [
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Preparing for emergencies: resuscitation guidelines for general dental practice. | Maintaining the knowledge and competence to deal with medical emergencies is an important part of all dental professionals' continuing professional development. This article aims to assist dental professionals in keeping up to date with the latest guidance. | 25,198,332 | [
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Management of sodium hypochlorite extrusion beyond the root apex during root canal treatment: a case report. | Sodium hypochlorite (NaOCl) is most commonly used as an irrigating solution in endodontic practice. This paper describes an incident of sodium hypochlorite extrusion past the apex (SHEPA) of the UR3. Management of the condition resulted in hospitalisation of the patient, and intravenous antibiotic and steroid therapy. ... | 25,198,335 | [
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0.1877141,
0.0695029... |
Study methods in evidence-based surgery: methodological impediments and suggested approaches for the creation and transfer of knowledge in surgery. | Since its introduction more than 20 years ago, evidence-based medicine has become an important principle in the daily routine of clinicians around the globe. Nevertheless, many surgical interventions are still not based on high-quality evidence from clinical trials. This is partially due to the fact that surgical trial... | 25,198,359 | [
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Ring enlargement reaction of C,N-cyclic-N'-acyl azomethine imines with sulfonium ylide: an efficient synthesis of 3-benzazepine derivatives. | Highly efficient formation of 3-benzazepine derivatives has been achieved, based on the ring expansion reaction of C,N-cyclic-N'-acyl azomethine imines with sulfonium ylide generated in situ from the corresponding sulfonium salt. The reactions proceeded smoothly to afford the tricyclic 3-benzazepine derivatives in good... | 25,198,375 | [
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Aerodigestive cancers: oral cancer. | Worldwide, approximately 260,000 new cases of oral cancer occur, and more than 125,000 mortalities are attributed to oral cancers each year. Oral cancers most commonly arise in the tongue, followed by the floor of the mouth and the lower gum. Tobacco and alcohol use are the major risk factors, although human papillomav... | 25,198,382 | [
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Acitretin-induced alopecia areata: a case report. | Alopecia areata is a common form of non-scarring hair disorder. The development of alopecia areata during anti-psoriatic treatment has been reported with the systemic therapies such as infliximab, etanercept, adalimumab, alefacept and efalizumab. Retinoid-induced alopecia areata on the eyelash and eyebrow has not been ... | 25,198,403 | [
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Acute transient myopic shift induced by red wine: a case report. | This case report described a patient presenting with unilateral transient myopic shift after consuming a lot of red wine. Ultrasound biomicroscopy detected annular shallow ciliary body detachment with supraciliary effusion, as well as a narrow chamber angle. The myopic shift was spontaneously resolved about one week af... | 25,198,409 | [
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Leg ulcer treatment outcomes with new ovine collagen extracellular matrix dressing: a retrospective case series. | The purpose of this study was to describe the rate of closure observed in venous leg ulcers during treatment with ovine collagen extracellular matrix dressings and compression. Fourteen patients with 23 wounds were retrospectively evaluated with respect to healing rates, time to closure, and weekly facility charge fees... | 25,198,432 | [
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Structure, functionality and tuning up of laccases for lignocellulose and other industrial applications. | Laccases (EC 1.10.3.2) are copper-containing oxidoreductases that have a relatively high redox potential which enables them to catalyze oxidation of phenolic compounds, including lignin-derived phenolics. The laccase-catalyzed oxidation of phenolics is accompanied by concomitant reduction of dioxygen to water via coppe... | 25,198,436 | [
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Microarray analysis of long non-coding RNA expression in human acute rejection biopsy samples following renal transplantation. | Rejection is still a major obstacle in long-term allograft survival of renal transplant recipients. Long non‑coding RNAs (lncRNAs) are an important class of pervasive RNAs involved in a variety of biological functions, and which are often found to be differentially expressed between healthy and pathological conditions.... | 25,198,465 | [
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Standardized methodology for transfemoral transcatheter aortic valve replacement with the Edwards Sapien XT valve under fluoroscopy guidance. | To provide a simplified, standardized methodology for a successful transfemoral transcatheter aortic valve replacement (TAVR) procedure with the Sapien XT valve in patients with severe aortic stenosis (AS). TAVR is currently reserved for patients with severe, symptomatic AS who are inoperable or at high operative risk.... | 25,198,489 | [
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How to implement an office-based vein program. | Peripheral venous disease is a highly prevalent problem affecting over 25-30 million people in the United States. Office-based treatment of superficial veins for chronic venous insufficiency is a fast-growing area with a recent surge of interest by cardiologists in this field. We describe our own experience with establ... | 25,198,494 | [
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Current estimates from the health interview survey, United States - 1968. | Data in this report for calendar year 1968 were obtained from a split sample, as were the data in the previous Current Estimates report (Series 10, No. 52). From January to June 1968; one-half the sample was interviewed using the "condition approach" and the other one-half was interviewed using. the "person approach." ... | 25,198,503 | [
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Ancient homology underlies adaptive mimetic diversity across butterflies. | Convergent evolution provides a rare, natural experiment with which to test the predictability of adaptation at the molecular level. Little is known about the molecular basis of convergence over macro-evolutionary timescales. Here we use a combination of positional cloning, population genomic resequencing, association ... | 25,198,507 | [
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Understanding Na₂Ti₃O₇ as an ultra-low voltage anode material for a Na-ion battery. | An in-depth understanding of Na2Ti3O7 as a Na-ion battery anode is reported. The battery performance is enhanced by carbon coating, due to increased electronic conductivity and reduced solid electrolyte interphase formation. Ti(4+) reduction upon discharge is demonstrated using in situ XAS. The self-relaxation behaviou... | 25,198,509 | [
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Serological evidence of Batai virus infections, bovines, northern Italy, 2011. | Batai virus (BATV) was identified in mosquitoes in the Caltignaga region of Novarra, northern Italy in 2009. Here, we report the identification of antibodies to BATV in serum samples that were taken from healthy bovines in that region in 2011. BATV has been associated with a mild febrile human illness and identified as... | 25,198,523 | [
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A monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (CEA) and restricts CEA expressing tumor growth. | Carcinoembryonic antigen (CEA) is one of the promising tumor antigens mainly associated with carcinoma of the colon, lung, breast, etc. and received wide attention for cancer immunotherapy. Neem leaf glycoprotein (NLGP), an effective immunomodulator, is able to generate humoral and cellular immune responses in murine t... | 25,198,527 | [
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A dietary-wide association study (DWAS) of environmental metal exposure in US children and adults. | A growing body of evidence suggests that exposure to toxic metals occurs through diet but few studies have comprehensively examined dietary sources of exposure in US populations. Our goal was to perform a novel dietary-wide association study (DWAS) to identify specific dietary sources of lead, cadmium, mercury, and ars... | 25,198,543 | [
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New mucoadhesive polymeric film for ophthalmic administration of acetazolamide. | This article reports the results concerning the design and manufacture of a novel polymeric film for ocular administration of acetazolamide (AZM), and a patent document presented to INPI- National Institute of Industrial/Intelectual Property. The system was designed using mucoadhesive polymers, such as carbomer (CB974P... | 25,198,555 | [
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Asthma knowledge level of child daycare center teachers' in Istanbul, Turkey. | Teachers are primarily responsible for supervising schoolchildren with asthma during school hours. The purpose of this study was to elucidate the level of knowledge of child daycare center teachers about asthma and factors affecting their knowledge. This study was performed on 297 teachers from 20 randomly selected chi... | 25,198,567 | [
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Barrier repair therapy for facial atopic eczema with a non-steroidal emollient cream containing rhamnosoft, ceramides and iso-leucine. A six-case report series. | Atopic eczema (AE) is a skin disease very common in paediatric population and face region is commonly involved. AE of the face represents a therapeutic challenge limiting the use, especially for long periods, of corticosteroid topical products due to the high risk of atrophic skin changes. Skin barrier alterations and ... | 25,198,568 | [
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Distinctive metabolite profiles in in-migrating Sockeye salmon suggest sex-linked endocrine perturbation. | The health of Skeena River Sockeye salmon (Onchorhychus nerka) has been of increasing concern due to declining stock returns over the past decade. In the present work, in-migrating Sockeye from the 2008 run were evaluated using a mass spectrometry-based, targeted metabolomics platform. Our objectives were to (a) invest... | 25,198,612 | [
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Non-surgical management of peri-implant diseases. | There are similarities between peri-implant diseases and periodontal diseases in terms of aetiology, pathogenesis and management. Patients with a past history of periodontitis are at greater risk of peri-implantitis and it is essential in partially dentate patients to ensure that control of periodontitis has been achie... | 25,198,642 | [
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Full mouth versus quadrant treatment in chronic periodontitis. | The aim of this review is to discuss the evidence for the management of chronic periodontitis, including methods of non-surgical therapy such as full mouth disinfection, full mouth debridement and conventional quadrant-by-quadrant therapy. Manual searches of Medline and Embase databases provided the relevant studies. M... | 25,198,643 | [
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A retro Diels-Alder route to diphosphorus chemistry: molecular precursor synthesis, kinetics of P2 transfer to 1,3-dienes, and detection of P2 by molecular beam mass spectrometry. | The transannular diphosphorus bisanthracene adduct P2A2 (A = anthracene or C14H10) was synthesized from the 7-phosphadibenzonorbornadiene Me2NPA through a synthetic sequence involving chlorophosphine ClPA (28-35%) and the tetracyclic salt [P2A2Cl][AlCl4] (65%) as isolated intermediates. P2A2 was found to transfer P2 ef... | 25,198,657 | [
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Epigenetically modified pancreatic carcinoma PANC-1 cells can act as cancer vaccine to enhance antitumor immune response in mice. | Pancreatic cancer is characterized as a type of gastrointestinal tumor with a poor prognosis and high degree of malignancy. CIITA gene was found highly methylated in pancreatic carcinoma cell line PANC-1 and responsible for the low expression of major histocompatability complex II (MHC-II) that may lead to immune evasi... | 25,198,660 | [
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Predictive potential of IL-18 -607 and osteopontin -442 polymorphism in interferon-based therapy of HCV infection in the Pakistani population. | The adaptive immune system plays an important role in response to interferon plus ribavirin treatment of hepatitis C virus (HCV) infection. Cytokines play a significant role in the adaptive immune system. The production of cytokines may be regulated by single nucleotide polymorphisms (SNPs). This study was designed to ... | 25,198,668 | [
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Generation and efficacy evaluation of recombinant classical swine fever virus E2 glycoprotein expressed in stable transgenic mammalian cell line. | Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), which is a highly contagious swine disease that causes significant economic loses to the pig industry worldwide. The envelope E2 glycoprotein of CSFV is the most important viral antigen in inducing protective immune response again... | 25,198,669 | [
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Statistical approach of functional profiling for a microbial community. | Metagenomics is a relatively new but fast growing field within environmental biology and medical sciences. It enables researchers to understand the diversity of microbes, their functions, cooperation, and evolution in a particular ecosystem. Traditional methods in genomics and microbiology are not efficient in capturin... | 25,198,674 | [
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Depersonalization in patients with persecutory delusions. | Delusions are, in part, attempts to explain confusing anomalous experience. Depersonalization, a key subset of anomalous experience, has been little studied in relation to persecutory delusions. The aims of this study were to assess the presence of depersonalization in patients with persecutory delusions and to examine... | 25,198,701 | [
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Raman modes of MoS2 used as fingerprint of van der Waals interactions in 2-D crystal-based heterostructures. | In this work, we use Raman spectroscopy as a nondestructive and rapid technique for probing the van der Waals (vdW) forces acting between two atomically thin crystals, where one is a transition metal dichalcogenide (TMDC). In this work, MoS2 is used as a Raman probe: we show that its two Raman-active phonon modes can p... | 25,198,732 | [
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Pediatric Heart Failure in the Developing World. | The exact prevalence of heart failure among children of developing countries is not known, as the data is limited. The relative frequency of different causes of pediatric heart failure varies widely across different countries and even among different parts of large countries like India. Children of developing countries... | 25,198,734 | [
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Beta-Blockers (Carvedilol) in Children with Systemic Ventricle Systolic Dysfunction - Systematic Review and Meta-Analysis. | Numerous prospective randomized clinical trials demonstrated favorable effect of beta-blockers in adults with chronic heart failure. However, effectiveness of beta blockers in pediatric patients with systemic ventricle systolic dysfunction was not recognized sufficiently. Limited number of pediatric patients might be t... | 25,198,735 | [
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Mechanisms of Beta-Blockers Action in Patients with Heart Failure. | Patients with chronic heart failure have prolonged sympathetic stimulation and subsequent worsening of the failing heart function. Beta-blockers (non-selective, cardio-selective, and non-selective with ancillary properties) counteract the effects of prolonged sympathetic stimulation. Beta-blocker therapy results in the... | 25,198,736 | [
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The Role of Beta-Blocker in Heart Failure in Adults with Congenital Heart Disease. | Thanks to the enormous progress in the field of cardiac surgery and paediatric cardiology since the mid of 20th century, more and more children with congenital heart defects reach the adulthood. This on the other hand encounter physician and patients various problems due to late complications after the heart surgery li... | 25,198,738 | [
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Life sciences HES-SO Valais/wallis: applied research for innovators. | The Institute of Life Technologies at the HES-SO Valais/Wallis in Sion focuses on the areas of peptide and protein technologies, life and bioresource technologies, food and natural products and diagnostic systems. With this network of complementary areas of expertise, the institute can offer industrial partners a broad... | 25,198,758 | [
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PfalDB: an integrated drug target and chemical database for Plasmodium falciparum. | Plasmodium falciparum is one of the deadliest protozoan parasite species among those that cause malaria. Uncontrolled use of antimalarial drugs has resulted in evolutionary selection pressure favoring high levels of resistance to antimalarials; currently P.falciparum shows resistance to all classes of antimalarials. Th... | 25,198,774 | [
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Combined cetuximab and celecoxib treatment exhibits a synergistic anticancer effect on human oral squamous cell carcinoma in vitro and in vivo. | The aim of the present study was to evaluate the potency of epidermal growth factor receptor (EGFR) pathway inhibition achieved by combining cetuximab (CET), an anti-EGFR monoclonal antibody, and celecoxib (CXB), a cyclooxygenase-2 (COX-2) inhibitor, in oral squamous cell carcinoma (OSCC) in vitro and in vivo. The OSCC... | 25,198,789 | [
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Direct determination of cone-beam geometric parameters using the helical phantom. | Estimation of a set of parameters that describe the geometry of the cone-beam computed tomography system plays an important role in the geometrical calibration. In the calibration process, the helical phantom consisting of spherical markers arranged on a helical trajectory has been widely applied. To directly determine... | 25,198,790 | [
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Femtosecond transient absorption spectroscopy of the medicinal agent curcumin in diamide linked γ-cyclodextrin dimers. | Curcumin is a biologically active polyphenol and a yellow pigment extracted from turmeric. Our previous study has shown effective encapsulation of curcumin using diamide linked γ-cyclodextrin dimers, namely 66γCD2su and 66γCD2ur, through cooperative 1:1 host-guest complexation. In this study, the excited-state dynamics... | 25,198,794 | [
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Preserving arteriovenous fistula outcomes during surgical training. | Arteriovenous fistulae (AVFs) are the preferred option for vascular access, as they are associated with lower mortality in hemodialysis patients than in those patients with arteriovenous grafts (AVGs) or central venous catheters (CVCs). We sought to assess whether vascular access outcomes for surgical trainees are comp... | 25,198,811 | [
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Postural alignment is altered in people with chronic stroke and related to motor and functional performance. | Trunk control is impaired after stroke but little is known about how changes in posture relate to other deficits. We examined spinal postural alignment in people with chronic stroke and explored the relationship between postural alignment and clinical measures. Twenty-one subjects with stroke and 22 age-matched healthy... | 25,198,868 | [
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Catalytic and regioselective oxidation of carbohydrates to synthesize keto-sugars under mild conditions. | A new catalytic and regioselective approach for the synthesis of keto-sugars is described. An organotin catalyst, Oc2SnCl2, in the presence of trimethylphenylammonium tribromide ([TMPhA](+)Br3(-)) accelerates the regioselective oxidation at the "axial"-OH group of 1,2-diol moieties in galactopyranosides. The reaction c... | 25,198,882 | [
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Curcumin induced human gastric cancer BGC-823 cells apoptosis by ROS-mediated ASK1-MKK4-JNK stress signaling pathway. | The signaling mediated by stress-activated MAP kinases (MAPK), c-Jun N-terminal kinase (JNK) has well-established importance in cancer. In the present report, we investigated the effects of curcumin on the signaling pathway in human gastric cancer BGC-823 cells. Curcumin induced reactive oxygen species (ROS) production... | 25,198,898 | [
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Palladium-catalyzed direct addition of arylboronic acids to 2-aminobenzonitrile derivatives: synthesis, biological evaluation and in silico analysis of 2-aminobenzophenones, 7-benzoyl-2-oxoindolines, and 7-benzoylindoles. | A palladium-catalyzed direct addition of arylboronic acids to unprotected 2-aminobenzonitriles has been developed, leading to a wide range of 2-aminobenzophenones with moderate to excellent yields. The transformation has broad scope and high functional group tolerance. Moreover, 2-oxoindoline-7-carbonitrile and indole-... | 25,198,908 | [
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Comparison of clinical characteristics and prognostic factors of combined pulmonary fibrosis and emphysema versus idiopathic pulmonary fibrosis alone. | The results of studies examining the outcome and the factors predicting prognosis in combined pulmonary fibrosis and emphysema (CPFE) have so far been contradictory. Our objective was to determine prognosis and the prognostic factors for CPFE. Of 108 consecutive idiopathic pulmonary fibrosis (IPF) patients admitted to ... | 25,198,924 | [
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Silodosin versus tamsulosin as medical expulsive therapy for distal ureteral stones: a prospective randomized study. | The aim of this study was to compare the safety and efficacy of silodosin (8 mg) versus tamsulosin (0.4 mg) as a medical expulsive therapy for distal ureteral stones. 136 patients (aged 18 years or older) had presented with renal colic, were diagnosed to have a single, unilateral, radiopaque, proximal ureteral stone (r... | 25,198,942 | [
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Conservative orthodontic treatment for skeletal open bite associated with amelogenesis imperfecta. | Amelogenesis imperfect (AI) is a hereditary dental condition that affects tooth enamel, resulting in small and discolored teeth, tooth sensitivity, poor esthetics, and anterior open bite associated with severe discrepancy in the vertical relation of the jaws. Treatment can be complex and includes an interdisciplinary a... | 25,198,953 | [
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An unusual place to find a lost needle in laparoscopic surgery. | Losing a needle during laparoscopic surgery is an uncommon but potentially challenging scenario for the surgeon. The prolonged operative time to search for a small retained foreign body such as a needle can cause clinical and medicolegal complications. As a result, it is considered a 'never event'. This report describe... | 25,198,959 | [
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Genomic insights into abdominal aortic aneurysms. | An individual's genetic background plays a significant role in his or her chances of developing an abdominal aortic aneurysm (AAA). This risk is likely to be due to a combination of multiple small effect genetic factors acting together, resulting in considerable difficulty in the identification of these factors. Method... | 25,198,969 | [
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A prospective study on the risk of glove fingertip contamination during draping in joint replacement surgery. | The aim of this prospective study was to investigate the risk of contamination of surgical gloves during preparation and draping in joint replacement surgery. During 46 hip and knee replacement procedures, the gloves of orthopaedic consultants (n=5) and registrars (n=3) were assessed for contamination immediately after... | 25,198,974 | [
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Mineral trioxide aggregate (MTA)-like materials: an update review. | Mineral trioxide aggregate (MTA) is a multi-application material used in endodontics. It is a mixture of a refined Portland cement and bismuth oxide and trace amounts of SiO₂, CaO, MgO, K₂SO₄, and Na₂SO₄. MTA powder is mixed with supplied sterile water in a 3:1 powder/liquid. Hydrated MTA has an initial pH of 10.2, whi... | 25,199,028 | [
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Dental implants' future: the need for a team approach. | Long-term success of dental implants is linked to well-trained implant surgeons and restorative dentists working together with the most advanced treatment modalities. General dentists are challenged to identify early in the diagnosis patients who are at greatest risk for developing complications and partner with specia... | 25,199,034 | [
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Group-based discrimination in judgments of moral purity-related behaviors: experimental and archival evidence. | Knowledge of individuals' group membership can alter moral judgments of their behavior. We found that such moral judgments were amplified when judgers learned that a person belonged to a group shown to elicit disgust in others. When a person was labeled as obese, a hippie, or "trailer trash," people judged that person'... | 25,199,041 | [
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Stereotype confirmation concerns predict dropout from cognitive behavioral therapy for social anxiety disorder. | There are high attrition rates observed in efficacy studies for social anxiety disorder, and research has not identified consistent nor theoretically meaningful predictors of dropout. Pre-treatment symptom severity and demographic factors, such as age and gender, are sometimes predictive of dropout. The current study e... | 25,199,046 | [
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Wild-type bone marrow transplant partially reverses neuroinflammation in progranulin-deficient mice. | Frontotemporal dementia (FTD) is a neurodegenerative disease with devastating changes in behavioral performance and social function. Mutations in the progranulin gene (GRN) are one of the most common causes of inherited FTD due to reduced progranulin expression or activity, including in brain where it is expressed prim... | 25,199,051 | [
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Preclinical evaluation of a novel cyanine dye for tumor imaging with in vivo photoacoustic imaging. | Photoacoustic imaging (PA imaging or PAI) has shown great promise in the detection and monitoring of cancer. Although nanocarrier-based contrast agents have been studied for use in PAI, small molecule contrast agents are required due to their ease of preparation, costeffectiveness, and low toxicity. Here, we evaluated ... | 25,199,057 | [
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-0.1456516,
0.2463323,
0.1018581,
0.1157505,
0.3289093,
0.2221769,
-0.1262183,
-0.1980913,
-0.002755513,
-0.02566424,
-0.3323712,
-0.430561,
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-0.3044022,
0.5123719,
0.2287492,
-0.08883869,
0.1910278,
0.3187754,
0.10783,
0.0... |
Mepolizumab treatment in patients with severe eosinophilic asthma. | Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or without oral glucocorticoids. In this randomized, double-blind, double-dummy study, we assigned 576 patients with recurrent asthma... | 25,199,059 | [
0.153523,
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0.007166468,
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0.2637285,
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0.236223,
0.02164273,
... |
Evaluation of HEMA released from four different adhesive systems by HPLC. | This study evaluated the elution of 2-hydroxyethyl methacrylate (HEMA) from 4 different adhesives, using high-performance liquid chromatography (HPLC). The adhesives were applied on a bovine dentin surface and polymerized using an LED curing unit (n=5). After polymerization, specimens were stored in 75% ethanol solutio... | 25,199,073 | [
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0.3702542,
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Pharmacokinetic comparison of sustained-release and standard buprenorphine in mice. | Effective pain medication is important for animal stewardship and valid research results. We compared the pharmacokinetic assessments of standard, immediate-release buprenorphine (Bup IR) and a sustained-release buprenorphine formulation (Bup SR Lab) in male C57BL/6J mice, a mouse strain commonly used in biomedical res... | 25,199,095 | [
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0.5429119,
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Conductance catheter measurement and effect of different anesthetics in a rat model of postresuscitation myocardial dysfunction. | We demonstrate the usefulness of left ventricular pressure-volume (PV) loops generated by the use of conductance catheter measurements and investigate the influence of the type of general anesthesia on postresuscitation myocardial dysfunction in a rat model of cardiac arrest (CA) and subsequent cardiopulmonary resuscit... | 25,199,096 | [
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Evaluation of carbon dioxide dissipation within a euthanasia chamber. | CO₂ euthanasia is used widely for small laboratory animals, such as rodents. A common necessity in many animal research facilities is to euthanize mice in sequential batches. We assessed the effects of several variables on the time it took for CO₂ to dissipate within a chamber. Using standard euthanasia time, changes i... | 25,199,098 | [
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Multisensory installations in residential aged-care facilities: increasing novelty and encouraging social engagement through modest environmental changes. | The current study examined the effect of an indoor simulated garden installation that included visual, auditory, and olfactory stimuli on resident well-being, compared to the effect elicited by a reminiscence installation and a control no-installation condition. A quasi-experimental ABA design was used (i.e., two inter... | 25,199,113 | [
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Changes in the levels of mannan-binding lectin and ficolins during head-down tilted bed rest. | Spaceflight studies and ground-based analogues of microgravity indicate a weakening of human immunity. Mannan-binding lectin (MBL) and H-, L-, and M-ficolin together constitute the lectin pathway and mediate the clearance of pathogens through complement activation. We hypothesized that simulated microgravity may weaken... | 25,199,121 | [
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0.03522057,
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0.02717384,
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Astronaut medical selection during the shuttle era: 1981-2011. | U.S. astronauts undergo extensive job-related screening and medical examinations prior to selection in order to identify candidates optimally suited for careers in spaceflight. Screening medical standards evolved over many years and after extensive spaceflight experience. These standards assess health-related risks for... | 25,199,124 | [
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0.03062372,
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Flight attendant radiation dose from solar particle events. | Research has suggested that work as a flight attendant may be related to increased risk for reproductive health effects. Air cabin exposures that may influence reproductive health include radiation dose from galactic cosmic radiation and solar particle events. This paper describes the assessment of radiation dose accru... | 25,199,125 | [
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0... |
Subject anxiety and psychological considerations for centrifuge-simulated suborbital spaceflight. | Anxiety and psychological concerns may pose a challenge to future commercial spaceflight. To help identify potential measures of anxiousness and indicators of flight-related stress, the psychiatric histories and anxiousness responses of volunteers exposed to G forces in centrifuge-simulated spaceflight acceleration pro... | 25,199,128 | [
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0.1384357,
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0.00779... |
Lymphomatosis cerebri mimicking iatrogenic Creutzfeldt-Jakob disease. | Lymphomatosis cerebri (LC) is a rare variant of primary central nervous system lymphoma (PCNSL) whereby individual lymphoma cells infiltrate the cerebral white matter without causing a mass effect. The disease characteristically presents as a rapidly progressive dementia, which opens an ample differential diagnosis of ... | 25,199,185 | [
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0.1885484,
0.406671,
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0.... |
[Anaphylaxis and anaphylactic shock]. | The anaphylactic shock is an acute, multisystemic and potentially fatal circulatory insufficiency, secondary to an allergic reaction. The prevalence of anaphylaxis is underestimated in the general population. Many studies have reported a prevalence of 0.05-2%. Multiple etiologies are incriminated in the pathogenesis of... | 25,199,227 | [
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0.1828263,
0.09274821,
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Synchronous and metachronous primary malignant colorectal tumors and associated primary extracolonic malignant tumors--diagnostics and surgical treatment. | The publications considering multiple primary tumors date back even to the XIXth century, however the scientific interest towards this problem still remains significant. The classification of these tumors is changing through the years, and their frequency remains higher than the expected one. The colon is one of the or... | 25,199,239 | [
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0.2379347,
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Clinical case of neuroendocrine malignant tumor with unusual localization in the adrenal cortex. | The authors present unusual clinical case with atypical diagnostic work-up and histological result of adrenal neuroendocrine carcinoma. | 25,199,242 | [
-0.1704633,
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[Interactions between the monogastric animal gut microbiota and the intestinal immune function--a review]. | The large numbers of microorganisms that inhabit mammalian gastro-intestine have a highly coevolved relationship with the host's health in nutrition, immunity and other aspects. There is a complex relationship between microbiota and immune system. Although they can inhibit the pathogens invade epithelial tissue, many o... | 25,199,246 | [
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0.3005891,
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-0.378... |
[Effects of different intensity exercise on blood glucose, adolescent obesity rats insulin sensitivity and RBP4]. | To discuss the effects of different intensity exercise on blood glucose, adolescent obesity rats insulin sensitivity and RBP4. The model of rats after 7 weeks, 32 rabbits of obesity prone rats were randomly divided into 4 groups, 8 rats in each group, respectively, control group, low intensity exercise group, moderate ... | 25,199,277 | [
0.2134694,
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0.0941683,
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[Regulation of ursolic acid on TNF-alpha and collagen in silicotic rats]. | To explore the regulation of ursolic acid on the expressions of TNF-alpha and collagen on Silicotic Rats. Seventy-five Wistar rats (class SPF) were divided into there groups according to the randomized block design, namely, control, model, ursolic acid groups with twenty-five rats in each group. SiO2 powders (250 mg/kg... | 25,199,287 | [
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0.2382582,
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0.2474025,
-0.3134601,
... |
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