title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Update: soccer injury and prevention, concussion, and chronic groin pain. | Soccer, or football, as it is known in much of the world, is one of the most popular sports in the world. The purpose of this article was to provide a concise update on select soccer-specific medical issues published in the last year as they relate to soccer injury and prevention, concussions, and chronic groin pain. B... | 25,211,620 | [
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Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential. | Epigenetic alterations are common in prostate cancer (PCa) and seem to contribute decisively to its initiation and progression. Moreover, aberrant promoter methylation is a promising biomarker for non-invasive screening. Herein, we sought to characterize EFEMP1 as biomarker for PCa, unveiling its biological relevance i... | 25,211,630 | [
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Ventilatory chemosensitivity, cerebral and muscle oxygenation, and total hemoglobin mass before and after a 72-day mt. Everest expedition. | We investigated the effects of chronic hypobaric hypoxic acclimatization, performed over the course of a 72-day self-supported Everest expedition, on ventilatory chemosensitivity, arterial saturation, and tissue oxygenation adaptation along with total hemoglobin mass (tHb-mass) in nine experienced climbers (age 37±6 ye... | 25,211,648 | [
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Associations of the fecal microbiome with urinary estrogens and estrogen metabolites in postmenopausal women. | The gut microbiota may influence the risk of breast cancer through effects on endogenous estrogens. The objective of the study was to investigate whether urinary estrogens and estrogen metabolites are associated with the diversity and composition of the fecal microbiome. This was a cross-sectional study among women enr... | 25,211,668 | [
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Process of speech acquisition and development of autistic children with or without autistic regression. | To compare the trajectory of acquisition speech and development of autistic children with or without autistic regression. The sample consisted of 64 children, aged 3-10 years, of both genders, diagnosed by a multidisciplinary team with autism. In the analysis were investigated during the interview: mention whether or n... | 25,211,684 | [
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Communication difficulties perceived by parents of children with developmental disorders. | The child's inclusion in his/her social-cultural context is very important to his/her adaptation and well-being. The family has a major role as a facilitator of this process. Therefore the difficulties of these families in communicating with children with communication disorders are an important issue to be assessed in... | 25,211,685 | [
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Computerized protocol of orofacial myofunctional evaluation with scores: usability and validity. | To test the usability of Computerized Orofacial Myofunctional Evaluation (OMES) protocol and analyze its validity. The study was divided into three stages: the first stage, production of the computerized version of OMES. The second stage was the validation of the user's interface, in which 100 OMES protocols of a datab... | 25,211,692 | [
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Treated wastewater irrigation: uptake of pharmaceutical and personal care products by common vegetables under field conditions. | Global water shortage is placing an unprecedented pressure on water supplies. Treated wastewater is a valuable water resource, but its reuse for agricultural irrigation faces a roadblock: the public concern over the potential accumulation of contaminants of emerging concern (CECs) into human diet. In the present study,... | 25,211,705 | [
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Moving beyond misuse and diversion: the urgent need to consider the role of iatrogenic addiction in the current opioid epidemic. | An epidemic of drug overdose deaths has led to calls for programs and policies to limit misuse and diversion of opioid medications. Any parallel call to consider the risk of iatrogenic addiction when treating pain has been muted in comparison. We have moved beyond questions of nonmedical use, abuse, and diversion to hi... | 25,211,712 | [
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The influence of race and comorbidity on the timely initiation of antiretroviral therapy among older persons living with HIV/AIDS. | We examined whether the timely initiation of antiretroviral therapy (ART) differed by race and comorbidity among older (≥ 50 years) people living with HIV/AIDS (PLWHA). We conducted frequency and descriptive statistics analysis to characterize our sample, which we drew from 2005-2007 Medicaid claims data from 14 states... | 25,211,735 | [
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Impact of county disadvantage on behavior problems among US children with cognitive delay. | We investigated relationships among cognitive delay, community factors, and behavior problems over 2 years in early childhood with a national sample of US families. Data were from 3 waves of the Early Childhood Longitudinal Study, Birth Cohort (2001-2005; n = 7650). We defined cognitive delay as the lowest 10% of menta... | 25,211,742 | [
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Sexually transmitted infections among incarcerated women: findings from a decade of screening in a Los Angeles County Jail, 2002-2012. | We describe and report findings from a screening program to identify sexually transmitted infections (STIs) and HIV among female inmates in Los Angeles County Jail. Chlamydia and gonorrhea screening was offered to entering female inmates. Women were eligible if they were (1) aged 30 years or younger, or (2) pregnant or... | 25,211,762 | [
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OVA-bound nanoparticles induce OVA-specific IgG1, IgG2a, and IgG2b responses with low IgE synthesis. | There is an urgent requirement for a novel vaccine that can stimulate immune responses without unwanted toxicity, including IgE elevation. We examined whether antigen ovalbumin (OVA) conjugated to the surface of nanoparticles (NPs) (OVA-NPs) with average diameter of 110nm would serve as an immune adjuvant. When BALB/c ... | 25,211,769 | [
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The structural basis of ATP as an allosteric modulator. | Adenosine-5'-triphosphate (ATP) is generally regarded as a substrate for energy currency and protein modification. Recent findings uncovered the allosteric function of ATP in cellular signal transduction but little is understood about this critical behavior of ATP. Through extensive analysis of ATP in solution and prot... | 25,211,773 | [
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The evaluation of the impact of a stand-biased desk on energy expenditure and physical activity for elementary school students. | Due to the increasing prevalence of childhood obesity, the association between classroom furniture and energy expenditure as well as physical activity was examined using a standing-desk intervention in three central-Texas elementary schools. Of the 480 students in the 24 classrooms randomly assigned to either a seated ... | 25,211,776 | [
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Closely consider finances, staffing when expanding office hours. | As primary care practices consider transforming to the Patient Centered Medical Home framework, one of the key concepts is increasing practice availability to patients. Adding nontraditional hours is worth exploring to meet patient needs and increase profitability. | 25,211,839 | [
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History of the child health and development book. Part 2: 1945-2000. | This is the second part of a historical review of the New Zealand child health and development record book (also known as the Well Child/Tamariki Ora Health book or Plunket book). It focuses on the years between 1945 and 2000. The first article highlighted how the book documented the development of "scientific motherin... | 25,211,915 | [
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[Prognostic value of ki-67 and vimentin markers in patients with metastatic kidney cancer]. | The study was aimed to determine the role of ki- 67 and vimentin markers in choosing the tactics of surgical treatment of patients with metastatic kidney cancer. The analysis of the results of treatment of 71 patients with metastatic renal cell carcinoma was performed. The first group included 16 (22.5%) patients, who ... | 25,211,928 | [
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[Features of endoscopic surgical treatment of urolithiasis in overweight patients]. | The article presents the results of endoscopic and nephrolithotripsy and ureterolithotripsy in 73 overweight patients (body mass index of over 30 kg/m2) with kidney stones and urinary tract infections of different locations compared with 30 patients without obesity. The features of choice of tactics of surgical treatme... | 25,211,929 | [
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[Crystal structures of plant uridine diphosphate-dependent glycosyltransferases]. | Glycosyltransferases (GTs) catalyze the transfer of a sugar residue of an activated sugar donor to an acceptor molecule. Many families 1 GTs utilize an uridine diphosphate (UDP) activated sugar as donor in the glycosylation reaction, and most of these belong to a group of GTs referred to as the UGTs. The relationship b... | 25,212,002 | [
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[High-efficiency expression of a receptor-binding domain of SARS-CoV spike protein in tobacco chloroplasts]. | Chloroplast-based expression system is promising for the hyper-expression of plant-derived recombinant therapeutic proteins and vaccines. To verify the feasibility of obtaining high-level expression of the SARS subunit vaccine and to provide a suitable plant-derived vaccine production platform against the severe acute ... | 25,212,009 | [
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[Effect of beclin1 on vincristine-induced dopaminergic neurons injury in zebrafish]. | To investigate vincristine-induced dopaminergic neurons toxicity and mechanism, and explore the molecular target to reduce the toxicity, zebrafish was chosen as a model animal, based on RT-PCR, Western blotting, whole mount in situ immunofluorescence and other technical means. The results showed that the transcription ... | 25,212,030 | [
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[Anti-tumor activity and mechanism of T03 in vitro and in vivo]. | The purpose of this study is to investigate the activity and mechanism of a new anti-tumor agent T03. MTT and colony formation assay were performed to determine anti-proliferation activity of T03 in vitro. Antitumor activity was observed by Renca xenograft model in vivo. The effect of T03 on cell cycle and apoptosis we... | 25,212,033 | [
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Vancomycin-resistant enterococci colonization and bacteremia in patients with hematological malignancies. | We retrospectively evaluated the rates of vancomycin-resistant enterococci (VRE) colonization and VRE-related infections in patients with hematological malignancies. All patients in the hematology department of the Ministry of Health Okmeydanı Training and Research Hospital, an 800-bed tertiary hospital in İstanbul, Tu... | 25,212,075 | [
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Protein-binding and antioxidant potential of phenolics of mangosteen fruit (Garcinia mangostana). | Phenolics were extracted from mangosteen fruit parts with 70% (v/v) aqueous acetone. The yield of crude extracts of phenolics (CP) ranged from 5.8% to 7.9%. The total phenolics (TPH) content ranged from 9.3mg to over 250mg of gallic acid equivalents per g of extract in the edible aril and skin, respectively. The format... | 25,212,134 | [
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Antioxidant effect of fractions from chicken breast and beef loin homogenates in phospholipid liposome systems. | The antioxidant effects of meat fractions from chicken breast and beef loin were compared. Five meat fractions - homogenate (H), precipitate (P), supernatant (S), high-molecular-weight (HMW) and low-molecular-weight (LMW) fractions - were prepared from chicken breast or beef loin. Each of the fractions were added to a ... | 25,212,135 | [
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Inhibition of melanosis formation in Pacific white shrimp by the extract of lead (Leucaena leucocephala) seed. | Lead (Leucaena leucocephala) seed extract was prepared using distilled water as a medium. An extraction yield of 26.16g/100g of seed was obtained after extraction at room temperature for 12h. Total phenolic and mimosine contents in the lead seed extract powder (LSEP) were 17.4g GAE/100g and 8.8g/100g, respectively. LSE... | 25,212,152 | [
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Antifungal activities of triterpenoids from the roots of Astilbe myriantha Diels. | During a search for plant extracts that possess activity against the fungi that cause diseases in plants, a 95% ethanol extract from the roots of Astilbe myriantha Diels showed inhibitory activity against Colletotrichum gloeosporioides. Bioassay-guided fractionation of the 95% ethanol extract led to the isolation of se... | 25,212,161 | [
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0.0628226,
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0.4306556,
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0.4597074,
0.2630235,
0.4478211,
0.07333075,
-0.0... |
Effects of high hydrostatic pressure (HHP) on bioaccessibility, as well as antioxidant activity, mineral and starch contents in Granny Smith apple. | The aim of this work was to study the effect of high hydrostatic pressure on the bioaccessibility of specific nutrients (antioxidant, minerals and starch) in apple and to establish processing conditions that maximise the health benefits. The apple was pressurised at 500MPa during 2, 4, 8 and 10min. The antioxidant acti... | 25,212,164 | [
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Perceptions of mental illness among Muslim general practitioners in South Africa. | Mental health literacy on the part of medical practitioners is an important component of mental healthcare. General practitioners (GPs) are typically the first doctors consulted by a person who is ill. Exploration of their perceptions regarding mental illness, aetiological issues and treatment is important. To investig... | 25,212,202 | [
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... |
Reliability and accuracy of the South African Triage Scale when used by nurses in the emergency department of Timergara Hospital, Pakistan. | Triage is one of the core requirements for the provision of effective emergency care and has been shown to reduce patient mortality. However, in low- and middle-income countries this strategy is underused, under-resourced and poorly researched. To assess the inter- and intra-rater reliability and accuracy of nurse tria... | 25,212,207 | [
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0.4740792,
0.09172463... |
Maternal educational level and children's healthy eating behaviour: role of the home food environment (cross-sectional results from the INPACT study). | The aims of this study are 1) to investigate the association between maternal educational level and healthy eating behaviour of 11-year-old children (fruit, vegetables and breakfast consumption), and 2) to examine whether factors in the home food environment (parental intake of fruit, vegetables and breakfast; rules ab... | 25,212,228 | [
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0.127324,
0.3847559,
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Germacranolides and their diversity of Eupatorium heterophyllum collected in P. R. China. | Eight new hydroperoxides and a new enone of germacrane-type sesquiterpenoids were isolated from the aerial parts of eight different samples of Eupatorium heterophyllum DC. (Asteraceae) collected in P. R. China. The structures were determined based on spectroscopic analyses. Seven of the eight samples produced hiyodoril... | 25,212,243 | [
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... |
Low-intensity aerobic exercise mitigates exercise-induced bronchoconstriction by improving the function of adrenal medullary chromaffin cells in asthmatic rats. | Exercise is one of the most common triggers of bronchoconstriction in patients with asthma. The low levels of circulating epinephrine produced by the adrenal medullary chromaffin cells (AMCCs) are associated with exercise-induced bronchoconstriction (EIB) in asthmatics. In the present study, we tested the hypothesis th... | 25,212,248 | [
-0.2168165,
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0.1922052,
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The intergenerational transmission of ethnic essentialism: how parents talk counts the most. | The present study analyzed the role of parents as potential sources of children's essentialist beliefs about ethnicity. We tested 76 parent-child (5-year-olds) dyads of Jewish Israeli parents from three social groups, defined by the kindergartens children attended: national religious, secular, or Jewish-Arab integrated... | 25,212,249 | [
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... |
Observational studies of the association between glucose-lowering medications and cardiovascular outcomes: addressing methodological limitations. | Recent years have witnessed a growing body of observational literature on the association between glucose-lowering treatments and cardiovascular disease. However, many of the studies are based on designs or analyses that inadequately address the methodological challenges involved. We reviewed recent observational liter... | 25,212,258 | [
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... |
A vascular mechanism for high-sodium-induced insulin resistance in rats. | High sodium (HS) effects on hypertension are well established. Recent evidence implicates a relationship between HS intake and insulin resistance, even in the absence of hypertension. The aim of the current study was to determine whether loss of the vascular actions of insulin may be the driving factor linking HS intak... | 25,212,260 | [
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0.1166951,
-0.0457592,
... |
The mediating effect of 'bothersome' urinary incontinence on help-seeking intentions among community-dwelling women. | To explore the mediating effect of bother of urinary incontinence between urinary incontinence severity and help-seeking intentions and detect whether the International Consultation on Incontinence Questionnaire-UI Short Form could be a valid measure to delineate bothersome urinary incontinence. Urinary incontinence is... | 25,212,267 | [
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Delayed posterior circulation insufficiency in pediatric moyamoya disease. | Approximately 30% of patients with moyamoya disease (MMD) have presented with involvement of the posterior circulation, mainly the posterior cerebral artery (PCA). Diagnosis of delayed progression of PCA stenosis in MMD may be difficult due to the diversity in clinical features. The goal of this study was to evaluate p... | 25,212,285 | [
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0... |
Advanced glycation end products inhibitors from Alpinia zerumbet rhizomes. | Advanced glycation end products (AGEs) are major factors responsible for the complication of diabetes. The present study was carried out to investigate the inhibitory activities on fructosamine adduct and α-dicarbonyl formations by hexane extracts of various parts of Alpinia zerumbet. Furthermore, we isolated two previ... | 25,212,289 | [
-0.2614065,
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0.1361408,
0.3446966,
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Different tastants and low-caloric sweeteners induce differential effects on the release of satiety hormones. | Recent studies have found different types of taste receptors located along the intestine. However, the effect of tastants, and in particular sweet tastants, on satiety hormone release is still unknown. STC-1 cells were incubated with different concentrations of bitter, sour, sweet, salty, and umami tastants. After incu... | 25,212,292 | [
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0.05593361,
0.1722764,
0.4575053,
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... |
The use of β-glucan as a partial salt replacer in high pressure processed chicken breast meat. | The effect of various ingredients such as sodium chloride (NaCl), sodium tripolyphosphate (STPP) and β-glucan (BG) on the biochemical properties of chicken breast proteins during temperature assisted high pressure processing was studied. Total protein solubility revealed that 600MPa pressure and 40(o)C are critical for... | 25,212,297 | [
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0.1332708,
0.1756522,
0.0037... |
Screening of the polyphenol content of tomato-based products through accurate-mass spectrometry (HPLC-ESI-QTOF). | Tomatoes, the second most important vegetable crop worldwide, are a key component in the so-called "Mediterranean diet" and its consumption has greatly increased worldwide over the past 2 decades, mostly due to a growing demand for tomato-based products such as ketchups, gazpachos and tomato juices. In this work, tomat... | 25,212,313 | [
-0.06037944,
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Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. | Rabdosia serra has been used in traditional Chinese medicine for centuries. In order to illustrate the pharmaceutical activity of R. serra as hypoglycaemic and skin-whitening agents, rosmarinic acid (confirmed as the major compound in R. serra), methyl rosmarinate and pedalitin isolated from R. serra were evaluated for... | 25,212,314 | [
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Fungi, mycotoxins and phytoalexin in peanut varieties, during plant growth in the field. | The aim of the present study was to analyze the mycobiota, occurrence of mycotoxins (aflatoxins and cyclopiazonic acid), and production of phytoalexin (trans-resveratrol) in two peanut varieties (Runner IAC 886 and Caiapó) during plant growth in the field. Climatic factors (rainfall, relative humidity and temperature) ... | 25,212,324 | [
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0.2350796... |
Identification of a novel food-derived collagen peptide, hydroxyprolyl-glycine, in human peripheral blood by pre-column derivatisation with phenyl isothiocyanate. | Peptides in the blood of subjects before and after collagen hydrolysate ingestion were fractionated by ion exchange and size-exclusion chromatographies and then derivatised with phenyl isothiocyanate. The derivatives were characterised by reserved phase (RP)-HPLC. Prolyl-hydroxyproline (Pro-Hyp), which has been identif... | 25,212,331 | [
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Demonstration of the presence of aminoreductone formed during the Maillard reaction in milk. | The Maillard reaction is a common chemical reaction that occurs in food and it generates multiple reaction products. Aminoreductone (AR) is one of the early-stage Maillard reaction products. At present the formation of AR has only been demonstrated in a model system consisting of a monosaccharide or disaccharide and an... | 25,212,341 | [
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0.3740955,
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... |
Linseed oil stabilisation with pure natural phenolic compounds. | Linseed has been used for a very long time in human and animal nutrition. Currently, there is an increasing interest in linseed oil because of its particularly high content in α-linolenic acid (ALA), an omega-3 fatty acid (FA). Unfortunately, ALA turns also the oil extremely sensitive to oxidation. This study aimed at ... | 25,212,361 | [
0.09523157,
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Matrix solid phase dispersion extraction of ginsenosides in the leaves of Panax ginseng C.M. Mey. | The matrix solid phase dispersion (MSPD) was applied to the extraction of eight kinds of ginsenosides from the leaves of Panax ginseng C.M. Mey. The experimental conditions were examined and optimised. The extracts were analysed by high performance liquid chromatography (HPLC). When the diatomaceous earth was used as d... | 25,212,364 | [
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0.07351075,
0.312094,
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Analysis of roasted and unroasted Pistacia terebinthus volatiles using direct thermal desorption-GCxGC-TOF/MS. | The objective of this study was to determine the effects of roasting time on volatile components of Pistacia terebinthus L., a fruit growing wild in Turkey. The whole fruit samples were pan roasted for 0, 5, 10, 15, 20 and 25min at 200°C. Volatile compounds were isolated and identified using the direct thermal desorpti... | 25,212,365 | [
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0.6096762,
0.5930925,
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Bio-nanogate controlled enzymatic reaction for virus sensing. | The objective of this study was to develop an aptamer-based bifunctional bio-nanogate, which could selectively respond to target molecules, and control enzymatic reaction for electrochemical measurements. It was successfully applied for sensitive, selective, rapid, quantitative, and label-free detection of avian influe... | 25,212,377 | [
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0.3241005,
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Deterministic lateral displacement for particle separation: a review. | Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow with a resolution of down to 10 nm. For 10 years, DLD has been extensively studied, employed and modified by researchers in terms of... | 25,212,386 | [
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0.04108261,
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Complete genome sequence of the first non-Asian isolate of Bombyx mori nucleopolyhedrovirus. | Brazil is one of the largest silk producers in the world. The domesticated silkworm (Bombyx mori) was formally introduced into the country in the twentieth century, and the state of Paraná is the main national producer. During larval stages, B. mori can be afflicted by many different infectious diseases, which lead to ... | 25,212,430 | [
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0.5302857,
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0.03614145,
0.5193068,
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Postoperative dysesthesia in lumbar three-column resection osteotomies. | Three-column lumbar spinal resection osteotomies including pedicle subtraction osteotomy (PSO), vertebral column resection (VCR), and total en bloc spondylectomy (TES) can potentially lead to dorsal root ganglion (DRG) injury which may cause postoperative dysesthesia (POD). The purpose of retrospective study was to des... | 25,212,452 | [
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Conserved features and major differences in the outer membrane protein composition of chlamydiae. | Chlamydiae are a highly successful group of obligate intracellular bacteria infecting a variety of eukaryotic hosts. Outer membrane proteins involved in attachment to and uptake into host cells, and cross-linking of these proteins via disulfide bonds are key features of the biphasic chlamydial developmental cycle. In t... | 25,212,454 | [
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BAG3 facilitates the clearance of endogenous tau in primary neurons. | Tau is a microtubule associated protein that is found primarily in neurons, and in pathologic conditions, such as Alzheimer's disease (AD) it accumulates and contributes to the disease process. Because tau plays a fundamental role in the pathogenesis of AD and other tauopathies, and in AD mouse models reducing tau leve... | 25,212,465 | [
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Neuroanatomic and cognitive abnormalities in attention-deficit/hyperactivity disorder in the era of 'high definition' neuroimaging. | The ongoing release of the Human Connectome Project (HCP) data is a watershed event in clinical neuroscience. By attaining a quantum leap in spatial and temporal resolution within the framework of a twin/sibling design, this open science resource provides the basis for delineating brain-behavior relationships across th... | 25,212,469 | [
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Development and validation of InnoQuant™, a sensitive human DNA quantitation and degradation assessment method for forensic samples using high copy number mobile elements Alu and SVA. | There is a constant need in forensic casework laboratories for an improved way to increase the first-pass success rate of forensic samples. The recent advances in mini STR analysis, SNP, and Alu marker systems have now made it possible to analyze highly compromised samples, yet few tools are available that can simultan... | 25,212,510 | [
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Indicators of newborn screening for congenital hypothyroidism in Sri Lanka: program challenges and way forward. | Many of the countries in the Asia Pacific Region are just initiating newborn screening programs for selected metabolic and other congenital disorders. The present study is aimed at evaluating the congenital hypothyroidism screening program in the Southern region of Sri Lanka in terms of coverage, effectiveness of detec... | 25,212,576 | [
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Nodal occult metastases in intermediate- and high-risk prostate cancer patients detected using serial section, immunohistochemistry, and real-time reverse transcriptase polymerase chain reaction: prospective evaluation with matched-pair analysis. | The purpose of the study was to prospectively evaluate the incidence of nodal OCM assessed using SS, IHC, and RT-PCR in prostate cancer patients compared with the standard pathological evaluation (SPE), and to evaluate short-term oncological outcomes of patients with OCM. Fifty-four consecutive patients with intermedia... | 25,212,578 | [
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The comparative experiences of women in control: diabetes self-management education in a virtual world. | The purpose was to characterize participants' experiences of a diabetes self-management (DSM) education program delivered via a virtual world (VW) versus a face-to-face (F2F) format. Participants included a randomly selected sample of participants who completed the Women in Control study. Four focus groups were conduct... | 25,212,580 | [
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Genome sequence of a salmonella phage used to control salmonella transmission in Swine. | Salmonella shedding in swine often increases in response to transportation and lairage. We previously demonstrated that such increases can be limited by directly feeding microencapsulated Salmonella bacteriophages. Here we present the genome sequence of vB_SalM_SJ_3, a broader spectrum Viuna-like Salmonella phage used ... | 25,212,610 | [
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Draft Genome Sequence of Pseudoalteromonas sp. Strain A2, an Isolate with High Antioxidative Activity from Arctic Seawater. | Here we report the draft genome sequence of Pseudoalteromonas strain A2, isolated from Arctic seawater in the pack-ice zone, which has high antioxidative activity against H2O2. The genomics information of this strain will facilitate the study of antioxidative mechanisms, cold adaptation properties, and evolution of thi... | 25,212,616 | [
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The expression and function of gelatinolytic activity at the rat neuromuscular junction upon physical exercise. | The gelatinases MMP-9 and MMP-2 have been implicated in skeletal muscle adaptation to training; however, their specific role(s) in the different muscle types are only beginning to be unraveled. Recently, we found that treadmill running increased the activity and/or expression of these enzymes in myonuclei and in activa... | 25,212,659 | [
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Neurodevelopmental outcome for offspring of women treated for antenatal depression: a systematic review. | The aim of this systematic review is to appraise existing literature on the effects of treatments for antenatal depression on the neurodevelopment outcomes of the offspring. We conducted a systematic review of the literature to identify studies on different kinds of treatments for antenatal depression (antidepressants ... | 25,212,663 | [
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Unexpected post-mortem diagnosis of systemic sclerosis presenting as pneumatosis intestinalis: revised diagnostic criteria and medicolegal implications. | Systemic sclerosis is a challenging diagnosis for clinicians and pathologists alike due to its protean manifestations and often insidious onset, particularly in cases without significant titres of auto-antibodies. Herein we present a case of a female in her sixties who died rapidly following a clinical diagnosis of pne... | 25,212,670 | [
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Self-regulated route to ternary hybrid nanocrystals of Ag-Ag2S-CdS with near-infrared photoluminescence and enhanced photothermal conversion. | Developing hybrid nanocrystals is a hot topic in materials science. Herein, a ternary hybrid nanocrystal, Ag-Ag2S-CdS, combining near infrared emission and photothermal conversion properties was demonstrated. The ternary Ag-Ag2S-CdS hybrid nanocrystals with cubic shape and uniform size were synthesized by a simple one-... | 25,212,685 | [
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Accuracy of calculated arterial saturation in oxygen in neonatal foals and effects of monitor, sensor, site of sensor placement, and degree of hypoxemia on the accuracy of pulse oximetry. | To (1) assess the agreement between calculated values for arterial hemoglobin saturation of oxygen (SaO2 ) and values obtained by co-oximetry, (2) assess the accuracy of 2 pulse oximetry monitors for measurement of SaO2 in foals, and for each monitor, and (3) determine the optimal combination of sensor type and site of... | 25,212,699 | [
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[Chronic kidney disease in Primary Health Care: prevalence and associated risk factors]. | To determine the prevalence of chronic kidney disease and associated risk factors in subjects over 60 years of age, as well as its staging by determining the glomerular filtration rate (GFR). Cross-sectional observational study. Primary Health Care. Patients≥60 years of age who were seen in 40 Primary Health Care centr... | 25,212,720 | [
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Results of Laboratory Testing of 15 Cookstove Designs in Accordance with the ISO/IWA Tiers of Performance. | The widespread adoption and sustained use of modern cookstoves has the potential to reduce harmful effects to climate, health, and the well-being of approximately one-third of the world's population that currently rely on biomass fuel for cooking and heating. In an effort to understand and develop cleaner burning and m... | 25,212,724 | [
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Are distance-dependent statistical potentials considering three interacting bodies superior to two-body statistical potentials for protein structure prediction? | Distance-based statistical potentials have long been used to model condensed matter systems, e.g. as scoring functions in differentiating native-like protein structures from decoys. These scoring functions are based on the assumption that the total free energy of the protein can be calculated as the sum of pairwise fre... | 25,212,727 | [
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Activity of ZnO polar surfaces: an insight from surface energies. | The calculation of the accurate surface energies for (0001) surfaces of wurtzite ZnO is difficult because it is impossible to decouple the two inequivalent (0001)-Zn and (0001¯)-O surfaces. By using a heterojunction model we have transformed the uncertainty of the surface energies into that of interface energies which ... | 25,212,731 | [
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The protozoan parasite Trichomonas gallinae causes adult and nestling mortality in a declining population of European Turtle Doves, Streptopelia turtur. | Studies incorporating the ecology of clinical and sub-clinical disease in wild populations of conservation concern are rare. Here we examine sub-clinical infection by Trichomonas gallinae in a declining population of free-living European Turtle Doves and suggest caseous lesions cause mortality in adults and nestlings t... | 25,212,735 | [
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Effectiveness of a home hazard modification program for reducing falls in urban community-dwelling older adults: A randomized controlled trial. | To evaluate the potential improvement of fall prevention awareness and home modification behaviors and to decrease indoor falls by applying a home hazard modification program (HHMP) in community-dwelling older adults followed up to 1 year in this randomized controlled trial. The present authors randomly assigned 130 ol... | 25,212,766 | [
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Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection. | A major immune evasion mechanism of HIV-1 is the accumulation of non-synonymous mutations in and around T cell epitopes, resulting in loss of T cell recognition and virus escape. Here we analyze primary CD8+ T cell responses and virus escape in a HLA B*81 expressing subject who was infected with two T/F viruses from a ... | 25,212,771 | [
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Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. | Sorting nexin 10 (SNX10), the unique member of the SNX family having vacuolation activity in cells, was shown to be involved in the development of autosomal recessive osteopetrosis (ARO) in recent genetic studies. However, the molecular mechanism of the disease-related mutations affecting the biological function of SNX... | 25,212,774 | [
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Plasma lactate concentrations in septic peritonitis: A retrospective study of 83 dogs (2007-2012). | To determine if absolute plasma lactate concentration or lactate clearance in dogs with septic peritonitis is associated with morbidity or mortality. Retrospective cohort study from 2007 to 2012. University teaching hospital. Eighty-three dogs with septic peritonitis were included. Patients had at least 1 plasma lactat... | 25,212,787 | [
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Practical Implementation of the 2013 AHA/ACC Blood Cholesterol Guidelines. | Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United States. Choosing the appropriate patients for whom to initiate statin therapy to reduce the risk of ASCVD is of paramount importance. The new AHA/ACC guidelines on the treatment of cholesterol emphasize a patient-centered approac... | 25,212,817 | [
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[Validation study on a multi-residue analysis of pesticides in agricultural products by using phosphoric acid treatment and GC-MS/MS]. | A rapid method for multi-residue determination of pesticides in agricultural products was validated. The sample was cut into pieces and placed into a mixer cup containing half weight amount of 10% phosphoric acid in order to suppress degradation of easily degraded pesticides, represented by captan, and then homogenized... | 25,212,821 | [
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Application of ozonated piggery wastewater for cultivation of oil-rich Chlorella pyrenoidosa. | Ozonated and autoclaved piggery wastewaters were compared for cultivation of oil-rich Chlorella pyrenoidosa by measuring nutrient removal from the medium and growth rate and lipid production of the microalgae. The removal rates of chemical oxygen demand, NH4(+)-N, total nitrogen and total phosphorus by C. pyrenoidosa w... | 25,212,822 | [
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Ethical use of social media to facilitate qualitative research. | Increasingly, qualitative health researchers might consider using social media to facilitate communication with participants. Ambiguity surrounding the potential risks intrinsic to social media could hinder ethical conduct and discourage use of this innovative method. We used some core principles of traditional human r... | 25,212,856 | [
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Effect of posterior tibial tendon dysfunction on unipedal standing balance test. | Foot pain and diminished functional capacity are characteristics of tibialis posterior tendon dysfunction (TPTD). This study tested the hypotheses that women with TPTD would have impaired performance of a unipedal standing balance test (USBT) and that balance performance would be related to the number of single limb he... | 25,212,864 | [
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-0.02557806,... |
Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma. | Monoclonal gammopathy of undetermined significance (MGUS) is characterized by an M spike less than 3 g/dL and a bone marrow containing fewer than 10% plasma cells without evidence of CRAB (hypercalcemia, renal insufficiency, anemia, or bone lesions). Light chain MGUS has an abnormal free light chain (FLC) ratio, increa... | 25,212,882 | [
-0.2908296,
0.1500815,
0.0757605,
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0.072206,
0.4809373,
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0.1325836,
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... |
Are OPG and RANKL involved in human fracture healing? | Human fracture healing is a complex interaction of several cytokines that regulate osteoblast and osteoclast activity. By monitoring OPG (osteoprotegerin) and sRANKL we aimed to possibly predict normal or impaired fracture healing. In 64 patients with a fracture of a long bone serum level of sRANKL and OPG were evaluat... | 25,212,894 | [
0.07043731,
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0.2580417,
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0.2945718,
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-0.076... |
Activation and regulation of pathogen sensor RIG-I. | Cells are equipped with a large set of pattern recognition receptors or sensors that detect foreign molecules such as pathogenic nucleic acids and initiate proinflammatory and antimicrobial innate immune responses. RIG-I is a cytosolic sensor that detects 5'-triphosphate double-stranded RNAs produced during infection. ... | 25,212,896 | [
-0.1631775,
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0.05141042,
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-0.08909295,
0.1628657,
0.1048121,
-0.2714... |
Obesity-induced cerebral hypoperfusion derived from endothelial dysfunction: one of the risk factors for Alzheimer's disease. | Increasing evidence supports the idea that chronic hypoperfusion in the brain is responsible for the pathogenesis underling Alzheimer's disease (AD). Obesity at midlife is associated with the risk of cognitive loss and AD at later life. Obesity decreases cerebral blood flow that is associated with decreased synthesis a... | 25,212,912 | [
-0.243963,
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0.3834645,
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0.05978917,
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0.2466844,
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... |
Prion-like Mechanisms in Alzheimer's Disease. | The misfolding and aggregation of specific proteins within nervous system occur in most age-associated neurodegenerative diseases including Alzheimer's disease (AD). This kind of disorders have been classified as the protein misfolding disease or proteopathy which share key biophysical and biochemical characteristics w... | 25,212,914 | [
-0.38781,
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Trajectories of age-related cognitive decline and potential associated factors of cognitive function in senior citizens of Beijing. | With a longer life expectancy and an increased prevalence of neurodegenerative diseases, investigations on trajectories of cognitive aging have become exciting and promising. This study aimed to estimate the patterns of age-related cognitive decline and the potential associated factors of cognitive function in communit... | 25,212,920 | [
-0.01042178,
0.3642602,
0.07788988,
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0.3832817,
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0.1844726,
0.3785003,
0.1344982... |
Developing cross-specialty endovascular simulation training. | Simulation is increasingly recognised as a valuable tool in training tomorrow's doctors. This technology has the potential to improve patient safety and address some of the challenges posed by recent changes in doctors' training, yet the uptake has been slow in the majority of institutions. In our own centre, we noted ... | 25,212,923 | [
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0.1775727,
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-0.6497658,
0.01075428,
-0.1938347,
0.03232008,
0.2279872,
0.05227693,
0.10152... |
Thirty-Five-Year Presence of African Swine Fever in Sardinia: History, Evolution and Risk Factors for Disease Maintenance. | Despite the implementation of control efforts and funds to fight against the disease, African swine fever (ASF) has been present in Sardinia since 1978. It has caused serious problems for both the industrial pig sector and the regional authorities in Sardinia, as well as the economy of Italy and the European Union, whi... | 25,212,957 | [
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0.2073631,
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0.0326581,
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0.1584777,
0.002717436,
0.2478686,
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0.2559363,
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0... |
Not all roads can be taken: development induces anisotropic accessibility in morphospace. | Morphospaces are quantitative representations of phenotype space that are widely used in studies of morphological evolution. Do current conceptualizations of morphospaces, however, appropriately reflect the evolutionary dynamics of organisms depicted in these spaces? Most empirical morphospace studies implicitly consid... | 25,212,955 | [
0.08453956,
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0.282206,
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[Complications associated with hyperglycemia in liver transplant patients]. | Hyperglycemia is a frequent phenomenon in hospitalized patients that is associated with negative outcomes. It is common in liver transplant patients as a result of stress and is related to immunosuppressant drugs. Although studies are few, a history of diabetes and the presentation of hyperglycemia during liver transpl... | 25,212,956 | [
0.06813771,
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0.04748408,
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0.05502839,
... |
Incidence of surgical site infection after spine surgery: what is the impact of the definition of infection? | Orthopaedic surgical site infections (SSIs) can delay recovery, add impairments, and decrease quality of life, particularly in patients undergoing spine surgery, in whom SSIs may also be more common. Efforts to prevent and treat SSIs of the spine rely on the identification and registration of these adverse events in la... | 25,212,963 | [
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0.3862945,
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0.08356947,
0.08320849,
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0.3737514,
0.056... |
Facial responses to basic tastes in the newborns of women with gestational diabetes mellitus. | To compare facial responses to basic tastes among newborns of women with and without gestational diabetes mellitus (GDM). Two-hundred and one healthy newborns, 100 from GDM women were studied at the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Brazil. Basic tastes were evaluated through administration... | 25,212,980 | [
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0.2784147,
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0.1215026,
0.0003988411,
0.1329137,
-... |
Shifts in microbiota species and fermentation products in a dietary model enriched in fat and sucrose. | The gastrointestinal tract harbours a 'superorganism' called the gut microbiota, which is known to play a crucial role in the onset and development of diverse diseases. This internal ecosystem, far from being a static environment, can be manipulated by diet and dietary components. Feeding animals with high-fat sucrose ... | 25,213,025 | [
0.06978916,
0.2172756,
0.03897015,
0.1341733,
0.3636386,
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0.3659371,
-0.1304965,... |
The role of atypical infections and macrolide therapy in patients with asthma. | For many years, the clinical benefit of macrolide use has been recognized in specific groups of patients with pulmonary disease. Dramatic improvement in survival of patients with diffuse panbronchiolitis is the most striking example of successful macrolide use as well as treatment of community acquired pneumonia caused... | 25,213,043 | [
0.009774237,
0.007850747,
-0.0512958,
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0.0783492,
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0.03616335,
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-0.2732227,
-0.04430844,
0.1530141,
-0.020... |
Impact of asthma exacerbations and asthma triggers on asthma-related quality of life in patients with severe or difficult-to-treat asthma. | Few data are available that evaluate the relationship among asthma exacerbations, asthma triggers, and asthma-related quality of life (QoL). To evaluate the impact of asthma exacerbations and asthma triggers on QoL. Patients with severe or difficult-to-treat asthma, ages ≥ 13 years (n = 2679) from the TENOR (The Epidem... | 25,213,047 | [
0.2258058,
0.1108169,
-0.2709444,
0.05009772,
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0.409448,
0.2104058,
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0.2198784,
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-... |
Fluticasone furoate-vilanterol 100-25 mcg compared with fluticasone furoate 100 mcg in asthma: a randomized trial. | The inhaled corticosteroid fluticasone furoate (FF) in combination with the long-acting β2-agonist vilanterol (VI) is under development for the treatment of asthma and chronic obstructive pulmonary disease. To compare the efficacy and safety of FF-VI and FF in patients (≥ 12 years old) with persistent asthma. In a rand... | 25,213,048 | [
0.02305517,
0.1484723,
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0.2364458,
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0.2701234,
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-... |
Dicopper(II) anthraquinophanes as multielectron reservoirs for oxidation and reduction: a joint experimental and theoretical study. | Two new dinuclear copper(II) metallacyclophanes with 1,4-disubstituted 9,10-anthraquinonebis(oxamate) bridging ligands are reported that can reversibly take and release electrons at the redox-active ligand and metal sites, respectively, to give the corresponding mono- and bis(semiquinonate and/or catecholate) Cu(II)2 s... | 25,213,086 | [
-0.2577934,
0.2923309,
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0.203207,
0.2198609,
0.09363773,
-0.2512732,
0.070... |
Social vulnerability as a predictor of mortality and disability: cross-country differences in the survey of health, aging, and retirement in Europe (SHARE). | Social factors are important for health; the concept of social vulnerability considers them holistically and can be quantified using a social vulnerability index (SVI). Investigate the SVI in relation to mortality and disability, independent of frailty, in middle-aged and older European adults, and examine how this rel... | 25,213,145 | [
-0.1958886,
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0.1818604,
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-0.3328678,
0.4025672,
-0.05846791,
0.008412818,
0.1481902,
0.523442,
-0.06272061... |
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