title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Tolerability of a probiotic in subjects with a history of methicillin-resistant Staphylococcus aureus colonisation. | Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen of major public health importance. Colonisation precedes infection; thus reducing MRSA carriage may be of benefit for reducing infection. Probiotics represent a novel approach to reducing MRSA carriage. We undertook a pilot feasibility randomised controll... | 25,213,147 | [
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Functional impairment in adolescents and young adults with emerging mood disorders. | Between 30 and 60% of adults with unipolar or bipolar disorders exhibit impairments across multiple domains. However, little is known about impaired functioning in youth with mood disorders. To examine the prevalence of objective, subjective and observer-rated disability in a large, representative sample of young peopl... | 25,213,156 | [
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Stress-induced mutation rates show a sigmoidal and saturable increase due to the RpoS sigma factor in Escherichia coli. | Stress-induced mutagenesis was investigated in the absence of selection for growth fitness by using synthetic biology to control perceived environmental stress in Escherichia coli. We find that controlled intracellular RpoS dosage is central to a sigmoidal, saturable three- to fourfold increase in mutation rates and as... | 25,213,168 | [
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Apoptosis mediated by phosphatidylserine externalization in the elimination of aneuploid germ cells during human spermatogenesis. | It has been described that aneuploidies trigger cell cycle checkpoints leading to apoptosis. The aim of this study was to assess the relationship between the presence of chromosomal abnormalities and apoptosis in germ cells and in Sertoli cells. Fourteen diagnostic testicular biopsies from infertile patients were proce... | 25,213,174 | [
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Manifestation of respect in the care of older patients in long-term care settings. | Respect is fundamental to ethical nursing practice. However, respect in the care of older people is seldom investigated from the perspective of patients and their next of kin. To describe the manifestation of respect in the care of older patients in long-term care settings from the perspective of older patients with me... | 25,213,177 | [
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Modeling tuberculosis in nonhuman primates. | Nonhuman primates have emerged as an excellent model of human tuberculosis, in large part because they recapitulate the full spectrum of infection outcome and pathology seen in humans. Several variables inherent to the nonhuman primate models of tuberculosis are discussed in this review, including the monkey species, M... | 25,213,189 | [
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How Taxol/paclitaxel kills cancer cells. | Taxol (generic name paclitaxel) is a microtubule-stabilizing drug that is approved by the Food and Drug Administration for the treatment of ovarian, breast, and lung cancer, as well as Kaposi's sarcoma. It is used off-label to treat gastroesophageal, endometrial, cervical, prostate, and head and neck cancers, in additi... | 25,213,191 | [
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Community treatment orders and the experiences of ethnic minority individuals diagnosed with serious mental illness in the Canadian mental health system. | The prevalence of Community Treatment Orders (CTOs) in the Western world has generated considerable discussion regarding best practices in the outpatient treatment of the seriously mentally ill. Although problems encountered by ethnic minority communities in the various health care systems have been studied to some deg... | 25,213,210 | [
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The association between Darier disease, bipolar disorder, and schizophrenia revisited: a population-based family study. | Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (ATP2A2) gene and previously reported to cosegregate with bipolar disorder and schizophrenia in occasional pedigrees. It is, however, unknown whether these associations exist also in... | 25,213,221 | [
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Poly-β-hydroxybutyrate (PHB) accumulating Bacillus spp. improve the survival, growth and robustness of Penaeus monodon (Fabricius, 1798) postlarvae. | Low larval survival resulting from suboptimal culture conditions and luminous vibriosis poses a major problem for the larviculture of penaeid shrimp. In this study, a poly-β-hydroxybutyrate (PHB) accumulating mixed bacterial culture (mBC; 48.5% PHB on cell dry weight) and two PHB accumulating bacterial isolates, Bacill... | 25,213,234 | [
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Detection of short-range chromatin interactions by chromosome conformation capture (3C) in yeast. | We describe a modified 3C ("chromosome conformation capture") protocol for detection of transient, short-range chromatin interactions in the yeast Saccharomyces cerevisiae. 3C was initially described by Job Dekker and involves formaldehyde cross-linking to stabilize transient chromatin interactions, followed by restric... | 25,213,247 | [
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Preparation of C18-functionalized Fe3O4@SiO2 core-shell magnetic nanoparticles for extraction and determination of phthalic acid esters in Chinese herb preparations. | The extraction and determination of phthalic acid esters (PAEs) residue in Chinese herbal preparations (CHP) by C18-functionalized magnetic nanoparticles (C18-FS-MNP) has been firstly performed. It was synthesized through coating Fe3O4 nanoparticles with sodium silicate, followed by freeze-drying technique and then mod... | 25,213,260 | [
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Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease. | Chronic obstructive pulmonary disease (COPD) and lung cancer are widespread lung diseases. Cigarette smoking is a high risk factor for both the diseases. COPD may increase the risk of developing lung cancer. Thus, it is crucial to be able to distinguish between these two pathological states, especially considering the ... | 25,213,261 | [
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The factors associated with medication errors in adult medical and surgical inpatients: a direct observation approach with medication record reviews. | Observing real situations in clinical practice can provide undetected information regarding problems in the medication process. The aims of this study were to describe the frequency, types, and severity of medication errors in medical and surgical inpatients as well as to study the relationship between medication error... | 25,213,297 | [
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Cardiac rehabilitation wait times and relation to patient outcomes. | Most cardiac rehabilitation (CR) associations have published guidelines recommending timely and early access. To review the effects of early CR initiation on patient outcomes, and to describe the wait times associated with positive outcomes. Studies were identified via a limited systematic search on key resource databa... | 25,213,305 | [
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Experience and the ever-changing brain: what the transcriptome can reveal. | The brain is an ever-changing organ that encodes memories and directs behavior. Neuroanatomical studies have revealed structural plasticity of neural architecture, and advances in gene expression technology and epigenetics have demonstrated new mechanisms underlying the brain's dynamic nature. Stressful experiences cha... | 25,213,333 | [
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Inhibition of serotonin transporter expression by C/EBPβ in LPS-activated macrophage cells (HD11). | Serotonin (5-hydroxytryptamine; 5-HT) transporter (5-HTT) is involved in inflammation and the stress response. In this study, we examined the regulation of 5-HTT expression in macrophage HD11 cells in response to bacterial LPS. Long-term exposure of cells to LPS (6-18 h) produced a decrease in 5-HTT mRNA expression. Ac... | 25,213,348 | [
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Progress of biological agents on psoriatic arthritis. | Psoriatic arthritis (PsA) is an inflammatory arthritis, characterized by mild arthralgia to severe joint deformities. Long term management of these diseases with nonsteroidal anti-inflammatory drugs (NSAIDs) and diseasemodifying antirheumatic drugs (DMARDs) is limited due to lack of efficacy and potential organ toxicit... | 25,213,361 | [
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Gradient-based electrical properties tomography (gEPT): A robust method for mapping electrical properties of biological tissues in vivo using magnetic resonance imaging. | To develop high-resolution electrical properties tomography (EPT) methods and investigate a gradient-based EPT (gEPT) approach that aims to reconstruct the electrical properties (EP), including conductivity and permittivity, of an imaged sample from experimentally measured B1 maps with improved boundary reconstruction ... | 25,213,371 | [
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Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4. | Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an inhibitory receptor found on immune cells. The consequences of mutations in CTLA4 in humans are unknown. We identified germline heterozygous mutations in CTLA4 in subjects with severe immune dysregulation from four unrelated families. Whereas Ctla4 heterozygous mice have ... | 25,213,377 | [
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Propagating phonons coupled to an artificial atom. | Quantum information can be stored in micromechanical resonators, encoded as quanta of vibration known as phonons. The vibrational motion is then restricted to the stationary eigenmodes of the resonator, which thus serves as local storage for phonons. In contrast, we couple propagating phonons to an artificial atom in t... | 25,213,379 | [
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Pregnane X Receptor and P-glycoprotein: a connexion for Alzheimer's disease management. | The translational failure between preclinical animal models and clinical outcome has alarmed us to search for a new strategy in the treatment of Alzheimer's disease (AD). Interlink between Pregnane X Receptor (PXR) and P-glycoprotein (Pgp) at the blood brain barrier (BBB) has raised hope toward a new disease modifying ... | 25,213,397 | [
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Tone and sentence perception in young Mandarin-speaking children with cochlear implants. | The purpose of this study was to examine the outcomes of cochlear implantation in young children in terms of (1) perception of lexical tones in quiet, (2) perception of sentences in quiet and in noise, (3) the effects of five demographic variables (i.e., preoperative hearing level, age at implantation, duration of coch... | 25,213,422 | [
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Prognosis of patients with intermediate-stage hepatocellular carcinomas based on the Child-Pugh score: subclassifying the intermediate stage (Barcelona Clinic Liver Cancer stage B). | Retrospective evaluation of intermediate-stage hepatocellular carcinoma (HCC) patient survival after undergoing chemoembolization based on the Child-Pugh score. Data of intermediate-stage HCC patients undergoing chemoembolization were gathered from 43 centers in Japan. Overall survival rates were compared with Child-Pu... | 25,213,426 | [
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Oral Candida carriage and prevalence of Candida species among Maras powder users and non-users. | The aim of this study was to investigate Candida carriage and species in Maras powder users and non-users. This study included 100 volunteering men in 12 cafés in the city of Kahramanmaras, Turkey. A questionnaire composed of questions about socio-demographic features and Maras powder use was filled in by the participa... | 25,213,478 | [
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[Anaplasic large cell lymphoma after breast prosthesis removal: about a case]. | There has recently been a new controversy about the appearance of a particular histological type of lymphoma, anaplasic large cell lymphoma, in patients carriers of breast implants, with no causal link has been established for the moment. We report the case of a patient of 67 years old with recurrent effusion breast af... | 25,213,486 | [
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Importance of blood cultures from peripheral veins in pediatric patients with cancer and a central venous line. | When an infection is suspected in a child with cancer and a central venous line (CVL), cultures are often only obtained from the CVL and not from a peripheral vein (PV). This study was undertaken to evaluate the importance of concomitant blood cultures from the CVL and a PV. Clinical data and the results of all culture... | 25,213,546 | [
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Vascular endothelial growth factor gene therapy improves nerve regeneration in a model of obstetric brachial plexus palsy. | The treatment of obstetric brachial plexus palsy has been limited to conservative therapies and surgical reconstruction of peripheral nerves. In addition to the damage of the brachial plexus itself, it also leads to a loss of the corresponding motoneurons in the spinal cord, which raises the need for supportive strateg... | 25,213,596 | [
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Multiple overlapping stent-assisted coiling of complex aneurysms: a single-center experience. | Coil embolization of wide-necked and fusiform aneurysms is challenging and is frequently associated with recanalization despite assistance of any additional device. The purpose of this study was to evaluate the feasibility and mid-term outcomes of complex aneurysms after multiple overlapping stent-assisted coiling (OSA... | 25,213,599 | [
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The development and validation of an early warning system to prevent the acquisition of 12-lead resting ECGs with interchanged electrode positions. | A fraction of routine resting ECG's are taken with electrode positions interchanged, leading to possible clinical misinterpretation. Develop and test a method to detect and prevent electrode reversals at the electrocardiograph before the ECG is acquired. The algorithm is based on QRS axis and P amplitudes for limb elec... | 25,213,624 | [
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Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma. | Anti-angiogenic therapy is a promising therapeutic strategy for the highly vascular and malignant brain tumor, glioblastoma (GBM), although current clinical trials have failed to demonstrate an extension in overall survival. The small molecule tyrosine kinase inhibitor axitinib that targets vascular endothelial growth ... | 25,213,669 | [
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Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysis. | Chloroquine is the first-line treatment for Plasmodium vivax malaria in most endemic countries, but resistance is increasing. Monitoring of antimalarial efficacy is essential, but in P. vivax infections the assessment of treatment efficacy is confounded by relapse from the dormant liver stages. We systematically review... | 25,213,732 | [
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Carbon nanofibers decorated with molybdenum disulfide nanosheets: synergistic lithium storage and enhanced electrochemical performance. | Traditional lithium-ion batteries that are based on layered Li intercalation electrode materials are limited by the intrinsically low theoretical capacities of both electrodes and cannot meet the increasing demand for energy. A facile route for the synthesis of a new type of composite nanofibers, namely carbon nanofibe... | 25,213,751 | [
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A prospective, observational study of added medium-dose cytosine arabinoside versus As2O3 for elderly patients with acute promyelocytic leukemia. | This open-label, prospective, observational study aimed to evaluate disease-free survival (DFS), overall survival (OS), PML-RARα polymerase chain reaction (PCR) monitoring and safety in elderly patients with de novo acute promyelocytic leukemia (APL) who were treated with either arsenic trioxide (As2O3) or medium-dose ... | 25,213,763 | [
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Angular-resolved magnetometry beyond triclinic crystals part II: torque magnetometry of Cp*ErCOT single-molecule magnets. | The experimental investigation of the molecular magnetic anisotropy in crystals in which the magnetic centers are symmetry related, but do not have a parallel orientation has been approached by using torque magnetometry. A single crystal of the orthorhombic organometallic Cp*ErCOT [Cp*=pentamethylcyclopentadiene anion ... | 25,213,767 | [
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Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. | Mesenchymal stem cell (MSC) therapy is promising for neuroprotection but there is no report of an appropriate in vitro model mimicking the situation of the in vivo retina that is able to test the effect of MSCs in suspension or encapsulated with/without a drug combination. This study aims to establish a viable mixed co... | 25,213,807 | [
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Nanobiodevice-based single biomolecule analysis, single-cell analysis, and in vivo imaging for cancer diagnosis, cancer theranostics, and iPS cell-based regenerative medicine. | Numerous nanobiodevices have been developed for cancer diagnosis through the analysis of cancer cells and cancer-related biomolecules, cancer gene therapy, and iPS cell-based regenerative medicine. A microchamber array, which is fabricated on a plastic chip, enables to develop a reliable circulating tumor cell (CTC) de... | 25,213,813 | [
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Entropy and long-range correlations in DNA sequences. | We analyze the structure of DNA molecules of different organisms by using the additive Markov chain approach. Transforming nucleotide sequences into binary strings, we perform statistical analysis of the corresponding "texts". We develop the theory of N-step additive binary stationary ergodic Markov chains and analyze ... | 25,213,853 | [
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Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency. | Folate-mediated one-carbon metabolism is a metabolic network of interconnected pathways that is required for the de novo synthesis of three of the four DNA bases and the remethylation of homocysteine to methionine. Previous studies have indicated that the thymidylate synthesis and homocysteine remethylation pathways co... | 25,213,861 | [
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A signal transducer and activator of transcription 3·Nuclear Factor κB (Stat3·NFκB) complex is necessary for the expression of fascin in metastatic breast cancer cells in response to interleukin (IL)-6 and tumor necrosis factor (TNF)-α. | IL-6 mediated activation of Stat3 is a major signaling pathway in the process of breast cancer metastasis. One important mechanism by which the IL-6/Stat3 pathway promotes metastasis is through transcriptional regulation of the actin-bundling protein fascin. In this study, we further analyzed the transcriptional regula... | 25,213,863 | [
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The Patterning of Sub-500 nm Inorganic Oxide Structures. | Elastomeric perfluoropolyether molds are applied to pattern arrays of sub-500 nm inorganic oxide features. This versatile soft-lithography technique can be used to pattern a wide range of materials; in this work inorganic oxides including TiO2 , SnO2 , ZnO, ITO, and BaTiO3 are patterned on a variety of substrates with ... | 25,213,887 | [
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0.00955354... |
Manipulating the Local Light Emission in Organic Light-Emitting Diodes by using Patterned Self-Assembled Monolayers. | Patterned organic light-emitting diodes are fabricated by using microcontact- printed self-assembled monolayers on a gold anode (see background figure). Molecules with dipole moments in opposite directions result in an increase or a decrease of the local work function (foreground picture), providing a direct handle on ... | 25,213,893 | [
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Investigating the composition of dissolved organic matter in natural water in rare earth mine using EEM-PARAFAC analysis. | In this study, we have characterized three fluorescent components of dissolved organic matter (DOM) in the surface and underground water of one rare earth element ore district by excitation-emission matrix (EEM) fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC). Two protein-like components (C1, ... | 25,213,919 | [
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Changes in phenolic profile and antioxidant activity during production of diced tomatoes. | Tomatoes and tomato-based products are rich in antioxidants such as carotenoids, vitamin C and polyphenols. The industrial processing of diced tomatoes involves heat treatments in which these antioxidant compounds may be potentially affected. In this study, we evaluate the effect of each separate step in the dice-makin... | 25,213,947 | [
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Characterisation of sweetpotato from Papua New Guinea and Australia: Physicochemical, pasting and gelatinisation properties. | The physicochemical and functional properties of flours from 25 Papua New Guinean and Australian sweetpotato cultivars were evaluated. The cultivars (white-, orange-, cream-, and purple-fleshed, and with dry matter, from 15 to 28g/100g), were obovate, oblong, elliptic, curved, irregular in shape, and essentially thin-c... | 25,213,955 | [
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A novel and enhanced approach for the assessment of the total carotenoid content of foods based on multipoint spectroscopic measurements. | We have devised a more sensible approach to estimate the carotenoid content of orange juices, which can be regarded as a model system of food with intricate carotenoid pattern. For this purpose spectroscopic information at several wavelengths and spectra of the juices and not from their carotenoid extracts were conside... | 25,213,969 | [
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The study of deoxynivalenol and its masked metabolites fate during the brewing process realised by UPLC-TOFMS method. | The co-occurrence of deoxynivalenol (DON) and deoxynivalenol-3-glucoside (DON-3-Glc) has been recently reported in malt and beer. In this study, the concentration changes were monitored within the brewing process of four beer brands: light, dark tap and two lagers, produced from ground malt mixtures differing in compos... | 25,213,970 | [
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Extraction and deglycosylation of flavonoids from sumac fruits using steam explosion. | The effects of steam explosion on the extraction and conversion of flavonoids from sumac fruits were studied. Steam explosion caused the reduction of particle size and led to the formation of large fissures and micropores on the sumac fruit coat. However, there was little change in total flavonoid content. A study of t... | 25,213,979 | [
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Sensory assessment and chemical measurement of astringency of Greek wines: Correlations with analytical polyphenolic composition. | The purpose of this study was to measure the astringency of selected Greek red wines and to assess the relationship between sensory and chemical data. Nine red wines produced by three native Greek grape varieties (agiorgitiko, xinomavro and mavrodafni) were used and their astringency and bitterness was assessed by a tr... | 25,213,982 | [
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Mercury speciation in seafood samples by LC-ICP-MS with a rapid ultrasound-assisted extraction procedure: Application to the determination of mercury in Brazilian seafood samples. | This paper describes a simple method for mercury speciation in seafood samples by LC-ICP-MS with a fast sample preparation procedure. Prior to analysis, mercury species were extracted from food samples with a solution containing mercaptoethanol, l-cysteine and HCl and sonication for 15min. Separation of mercury species... | 25,213,989 | [
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Respiratory failure after treatment of pneumothorax. | A 40-year-old man presented with an eight day history of left-side pleuritic chest pain and dyspnea. Chest examination revealed decreased air entry at the left lung. Chest X-ray examination revealed a large pneumothorax and a chest tube was successfully placed. Two hours after the procedure, auscultation revealed crack... | 25,214,007 | [
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Pre-angiography total ST-segment resolution is not a reliable predictor of an open infarct-related artery. | While the cutoffs of predictive value for ST-segment elevations resolution (STSR) following thrombolysis and/or primary PCI were well documented, the impact of pre-angiography STSR has not been established yet. The aim of this study is to assess prognostic utility of pre-angiography STSR to predict pre-procedural TIMI ... | 25,214,008 | [
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Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence. | Fibroblasts from the progeroid Nijmegen breakage syndrome that express a truncated version of the nibrin protein (NBN(p70)) undergo premature senescence and have an enlarged morphology with high levels of senescence-associated β-galactosidase, although they do not have F-actin stress fibres. Growth of these fibroblasts... | 25,214,013 | [
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Challenges in linking preclinical anti-microbial research strategies with clinical outcomes for device-associated infections. | Infections related to implanted medical devices have become a significant health care issue in recent decades. Increasing numbers of medical devices are in use, often in an aging population, and these devices are implanted against a background of increasing antibiotic-resistant bacterial populations. Progressively more... | 25,214,018 | [
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The non-aggregated aggrecan in the human intervertebral disc can arise by a non-proteolytic mechanism. | Analysis of both the aggregated and non-aggregated fractions of aggrecan isolated from adult human intervertebral disc using immunoblotting with antibodies specific for the different domains constituting the aggrecan core protein or atomic force microscopy revealed that many components contained the G1 domain. However,... | 25,214,019 | [
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0.01153898,
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0.01744616,
-0.3243656,
0.265969,
-0.1362092,
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0.4410183,
0.06082209,
-0.1430721,
... |
PMLABe diol synthesized by ring-opening polymerization of racemic benzyl β-malolactonate initiated by rare-earth trisborohydride complexes: an experimental and DFT study. | Polymer diols are a class of polymeric building blocks of high interest for the synthesis of complex macromolecular edifices. Rare-earth borohydride complexes are known as efficient initiators for the ring-opening polymerization (ROP) of cyclic esters, directly affording α,ω-dihydroxy-telechelic polyesters. Here, were ... | 25,214,039 | [
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0.4880378,
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Self-reported use of evidence-based medicine and smoking cessation 6 - 9 months after acute coronary syndrome: a single-centre perspective. | Good evidence exists to support the use of secondary prevention medications (aspirin, statins, beta-blockers and angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs)) and smoking cessation in patients after acute coronary syndromes (ACSs). Little is currently known about adherence to... | 25,214,049 | [
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0.355261,
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0.09221614,
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Injury severity in relation to seatbelt use in Cape Town, South Africa: a pilot study. | Injuries and deaths from road traffic collisions present an enormous challenge to the South African (SA) healthcare system. The use of restraining devices is an important preventive measure. To determine the relationship between seatbelt use and injury severity in vehicle occupants involved in road traffic collisions i... | 25,214,050 | [
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Efficacy of silkworm (Bombyx mori L.) chrysalis oil as a lipid source in adult Wistar rats. | The effects of silkworm chrysalis oil, rich in n-3 α-linolenic acid (ALA), on lipid metabolism in Wistar rats were investigated. The rats were fed diets containing 7% soybean oil (control), silkworm chrysalis oil (SWO), or fish oil (FO) for 8weeks. Plasma triglyceride and glucose levels were significantly lower in the ... | 25,214,076 | [
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... |
Antifungal activity of sourdough fermented wheat germ used as an ingredient for bread making. | This study aimed at investigating the antifungal activity of sourdough fermented (Lactobacillus plantarum LB1 and Lactobacillus rossiae LB5) wheat germ (SFWG). Preliminarily, methanol and water/salt-soluble extracts from SFWG were assayed by agar diffusion towards Penicillium roqueforti DPPMAF1. As shown by hyphal radi... | 25,214,083 | [
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0.4174981,
0.1324408,
0.12... |
Oxidative formation and structural characterisation of new α-pyranone (lactone) compounds of non-oxonium nature originated from fruit anthocyanins. | A new group of pyranoanthocyanin-derived polyphenolic compounds was recently found to occur in aged wines and named as oxovitisins, the spectrum of which displayed only a pronounced broad absorption peak around 370nm in the UV region, being quite different from that of anthocyanin-like chromenylium pigments which prese... | 25,214,087 | [
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0.3876519,
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Sulphated modification of a polysaccharide obtained from fresh persimmon (Diospyros kaki L.) fruit and antioxidant activities of the sulphated derivatives. | Free radicals and other reactive oxygen species (ROS) are believed to play significant roles in ageing as well as in a number of degenerative or pathological diseases. This paper reports the preparation, characterisation and potential antioxidant activity of a type of chemically sulphated polysaccharide isolated from f... | 25,214,099 | [
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0.1166981,
0.2746399,
0.01326... |
Early post-mortem sarcoplasmic proteome of porcine muscle related to protein oxidation. | Oxidative deterioration or modifications of proteins which appear during meat storage and processes can result in the impairment of technological, sensorial and nutritional qualities. Improving the quality involves a better understanding of the biochemical mechanisms responsible for protein oxidation in meat. For that ... | 25,214,101 | [
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0.01111268,
0.08900519,
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0.5643535,
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... |
Ascorbic acid enrichment of whole potato tuber by vacuum-impregnation. | The aim of this study was to evaluate the use of vacuum-impregnation (VI) for enriching the ascorbic acid content of whole potatoes. Whole potatoes were immersed in a 10% ascorbic acid (AA) solution. A vacuum pressure of 70cm Hg was applied for 0-60min, following atmospheric pressure restoration for 3h, while samples r... | 25,214,103 | [
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0.2962725,
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Antioxidant activity of carrot juice in gamma irradiated beef sausage during refrigerated and frozen storage. | The antioxidant activity of carrot juice in gamma irradiated beef sausage was studied. Four batches of beef sausage were prepared, in which the first batch was formulated with water as the control. The other batches were formulated with unconcentrated carrot juice, carrot juice concentrated by 35% and 60%, respectively... | 25,214,104 | [
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Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters. | Cardiovascular protection of deep-seawater (DSW) drinking water was assessed using high-fat/cholesterol-fed hamsters in this study. All hamsters were fed a high-fat/cholesterol diet (12% fat/0.2% cholesterol), and drinking solutions were normal distiled water (NDW, hardness: 2.48ppm), DSW300 (hardness: 324.5ppm), DSW90... | 25,214,107 | [
0.2798633,
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0.32862,
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0.3454902,
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... |
Antioxidative activity of water extract of sweet potato leaves in Taiwan. | This study reports the preparation of four varieties of water extract from sweet potato leaves from Taiwan, including TNG10, TNG57, TNG66 and YSP, and evaluates their antioxidative activity. The EC50 values (scavenging DPPH radicals) of TNG10, TNG57, TNG66 and YSP were 0.27±0.01, 0.19±0.01, 0.41±0.02, and 0.31±0.02mg/m... | 25,214,118 | [
-0.03740316,
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0.119692,
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0.3304775,
-0.046350... |
Gold nanoparticle modified conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrole-1-l) benzenamine for potential use as a biosensing material. | Gold nanoparticle (AuNP) modified conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine (SNS-NH2) was used as the biosensing platform for glucose analysis. Electrochemical measurements were carried out by following the consumed oxygen due to the enzymatic reaction of glucose oxidase (GOx) at -0.7V v... | 25,214,132 | [
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0.04600133,
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A rapid screening for adulterants in olive oil using DNA barcodes. | A distinctive methodology is developed to trace out the mixing into olive oil, which is marketed every year with 20% or more fraudulent oils. Such adulteration has been difficult to differentiate using fatty acid analysis and other available current techniques, as chemically fatty acids are same regardless of their sou... | 25,214,135 | [
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Quantitative analysis of phenolic compounds in Chinese hawthorn (Crataegus spp.) fruits by high performance liquid chromatography-electrospray ionisation mass spectrometry. | Eleven major phenolic compounds (hyperoside, isoquercitrin, chlorogenic acid, ideain, epicatechin, two procyanidin (PA) dimers, three PA trimers and a PA dimer-hexoside) were quantified in the fruits of 22 cultivars/origins of three species of the Chinese hawthorn (Crataegus spp.) by HPLC-ESI-MS-SIR. Hyperoside (0.1-0.... | 25,214,140 | [
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-... |
MicroRNA-10b indicates a poor prognosis of non-small cell lung cancer and targets E-cadherin. | MicroRNA-10b(miR-10b) has been reported to be dysregulated in some types of cancer and to play an important role in invasion and metastasis. It was previously found to be a tumor enhancer in NSCLC; however, its clinical significance in NSCLC has not been evaluated. We compared the expression levels of miR-10b in 73 pai... | 25,214,146 | [
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Introducing excess body weight in childhood and adolescence and comparison with body mass index and waist-to-height ratio. | Weight status in children and adolescents is commonly defined using age- and gender-corrected standard deviation scores for body mass index (BMI-SDS, also called z-scores). Values are not reliable for the extremely obese however. Moreover, paediatricians and parents may have difficulties understanding z-scores, and whi... | 25,214,151 | [
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... |
Utility of percutaneous dilatational tracheostomy in the inmediate postoperative period of liver transplant. | To determinate the safety of percutaneous dilatational tracheostomy (PDT) on hepatic allograft recipients. We reviewed the records of patients who underwent liver transplantation between October 2007 and April 2013, followed by PDT. In this time period, 25 liver recipients underwent PDT in our intensive care unit. We r... | 25,214,168 | [
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Validation of a 15-item care-related regret coping scale for health-care professionals (RCS-HCP). | Coping with difficult care-related situations is a common challenge for health-care professionals. How these professionals deal with the regrets they may experience following one of the many decisions and interventions they must make every day can have an impact on their own health and quality of life, and also on thei... | 25,214,189 | [
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... |
Effects of varicocele on serum testosterone and changes of testosterone after varicocelectomy: a prospective controlled study. | To examine the hypotheses that clinical varicoceles affect baseline serum total testosterone levels (T) and varicocelectomy improves T. This prospective, nonrandomized, controlled study involved 4 groups of adult men. Varicocele-infertile treatment group (VIT) included 66 men who underwent varicocelectomy. Thirty-three... | 25,214,202 | [
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Extreme phenotypic variability of thyroid dysgenesis in six new cases of congenital hypothyroidism due to PAX8 gene loss-of-function mutations. | Within the last two decades, heterozygous loss-of-function PAX8 mutations have been reported in patients with a wide degree of thyroid gland dysfunction and growth despite the presence of identical mutations. To search for PAX8 mutations in a cohort of patients with congenital hypothyroidism (CH) and various types of t... | 25,214,233 | [
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Concurrent changes in methyl jasmonate emission and the expression of its biosynthesis-related genes in Cymbidium ensifolium flowers. | Methyl jasmonate (MeJA) is one of most abundant scent compounds in Cymbidium ensifolium flowers. In this study, the emission of MeJA and its regulation mechanism were investigated. Our results showed that emission of MeJA in C. ensifolium flowers was controlled developmentally and rhythmically. It occurred in a tissue-... | 25,214,235 | [
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No evidence for association of insulin receptor substrate-1 Gly972Arg variant with type 2 diabetes mellitus in a mixed-ancestry population of South Africa. | The most common single-nucleotide polymorphism in the insulin receptor substrate-1 (IRS1) gene is Gly972Arg, which is associated with a 25% increased risk of developing diabetes. The mixed-ancestry population of South Africa (SA) has one of the highest prevalences of type 2 diabetes mellitus (T2DM) in Africa. To report... | 25,214,251 | [
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... |
Development of a training programme in disability assessment methidology based on international classification of functioning, disability and health (icf) for psychiatric disability claims in Georgia. | The new concept for social integration of people with disabilities pointed at the need to develop disability assessment methodology with the subsequent validization, based on modern approaches that conceptualise disability as arising from the interaction of a person's functional status with the physical, cultural and p... | 25,214,277 | [
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0.3656194,
0.02643325,
0.2440961,
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[Flexible ureterorenoscopy in obese patients: results from a large monocenter cohort]. | To analyze results and morbidity after flexible ureterorenoscopy (fURS) in patients with a body mass index (BMI)>30 kg/m² and to compare with results obtained in a large cohort of non-obese patients. We conducted a retrospective monocenter study including all fURS for urinary lithiasis performed in our institution b... | 25,214,292 | [
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The effect of active caspase-3 on degradation of chicken myofibrillar proteins and structure of myofibrils. | The objective of this study was to investigate the potential contribution of caspase-3 to meat postmortem tenderisation by examining the role of caspase-3 in the degradation of myofibrillar proteins and disruption of myofibril structure in vitro. Myofibrillar protein prepared from chicken muscle was incubated with EDTA... | 25,214,324 | [
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0.4539625,
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Water status and quality improvement in high-CO2 treated table grapes. | Unfreezable water (UFW) content in berry tissues (pulp, skin, seed) and rachis of table grape clusters stored at 0°C has been studied using differential scanning calorimetry. The effect of short exposure to high CO2 (20% CO2 for 3days) and the transfer to air were also studied. Water status of pulp tissues was related ... | 25,214,326 | [
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Determination of the change of flavonoid components as the defence materials of Citrus unshiu Marc. fruit peel against Penicillium digitatum by liquid chromatography coupled with tandem mass spectrometry. | A healthy fruit peel of Citrus unshiu Marc. and one infected by Penicillium digitatum were analysed for flavonoids via high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS) in the positive mode with selected ion monitoring (SIM). Among 16 flavonoid components characterised in C. unsh... | 25,214,328 | [
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Antioxidant and cholinesterases inhibitory activities of Verbascum xanthophoeniceum Griseb. and its phenylethanoid glycosides. | The members of Verbascum L. (Scrophulariaceae) are known to be rich in phenylethnoid glycosides, and among them Verbascum xanthophoeniceum is an endemic plant species for the Balkan region, Northwestern, and Southern Turkey. A scheme was developed for the isolation of the main active constituents that accumulate in pla... | 25,214,335 | [
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Effect of cooking on total vitamin C contents and antioxidant activity of sweet chestnuts (Castanea sativa Mill.). | In this work the total vitamin C contents (ascorbic acid+dehydroascorbic acid) and antioxidant activity of raw and cooked chestnuts was evaluated. The vitamin C contents of raw chestnuts varied significantly between the different cultivars (cv) studied and it varied from 400mg/kg dry weight (cv Lada) to 693mg/kg dry we... | 25,214,344 | [
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Changes in carotenoids during processing and storage of pumpkin puree. | Changes in the contents of carotenoids and their true retentions (% TR) during the production of puree of Cucurbita moschata 'Menina Brasileira' and of Cucurbita maxima 'Exposição' pumpkins and the stability of such compounds during 180days of storage were monitored by liquid chromatography coupled with a photodiode ar... | 25,214,348 | [
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Role of hydroxyl radical in modification of cell wall polysaccharides and aril breakdown during senescence of harvested longan fruit. | The effects of reactive oxygen species (ROS), especially hydroxyl radical (OH), on cellular wall disassembly in vitro and in vivo, and aril breakdown in longan fruit, were investigated. OH caused the disassembly of cell wall material (CWM) in vitro, demonstrated by the increases of total sugars and uronic acid released... | 25,214,349 | [
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0.332457,
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0.5894928,
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Control of the Maillard reaction by ferulic acid. | This study investigated how ferulic acid (FA) affects the formation of certain Maillard reaction products (MRPs), i.e., early MRPs, fluorescent and non-fluorescent advanced glycation end products (AGEs), and melanoidins in model systems. Glycation mixtures were prepared containing soy glycinin or bovine serum albumin (... | 25,214,350 | [
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0.1600408,
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... |
Solubility of disodium 5'-guanylate heptahydrate in aqueous methanol mixtures. | The solubility of disodium 5'-guanylate heptahydrate (5'-GMPNa2) in binary aqueous methanol solvent mixtures with the temperature ranging from 278.15 to 323.15K was measured by a dynamic method with a laser monitoring observation technique. The solubility data were correlated with the Combined Nearly Ideal Binary Solve... | 25,214,352 | [
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0.1670227,
-0.223521... |
How can we improve the use of essential evidence-based interventions? | Between 250,000-280,000 women die worldwide during pregnancy and childbirth each year and children in low- and middle-income countries are 56 times more likely to die before the age of 5 than children in high-income countries. This Editorial discusses the publishing of a supplement within Reproductive Health titled Ess... | 25,214,358 | [
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0.3950793,
-0.1089... |
The incentives created by a harm reduction approach to smoking cessation: Snus and smoking in Sweden and Finland. | Tobacco harm reduction involves advocating the use of a less harmful alternative to smoking for those users who are unwilling or unable to quit. The net effect of such an approach is unclear as it may create opposing incentives. Although some smokers may substitute toward this less harmful alternative, it may reduce th... | 25,214,359 | [
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0.1076171,
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0.4147012,
-0.00611588... |
Quality of life psychosocial characteristics in Greek patients with leg ulcers: a case control study. | Chronic leg ulcers are a public health problem that can have a significant impact on the patient's physical, socioeconomic and psychological status. The aim of this study is to evaluate the quality of life, anxiety and depression, self-esteem and loneliness in patients suffering from leg ulcers. A total of 102 patients... | 25,214,366 | [
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0.3532,
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Re-examining premature mortality in anorexia nervosa: a meta-analysis redux. | Anorexia nervosa (AN) is reported to have the highest premature mortality of any psychiatric disorder, but recent meta-analyses may have inflated estimates. We sought to re-estimate mortality after methodological corrections and to identify predictors of mortality. We included 41 cohorts from 40 peer-reviewed studies p... | 25,214,371 | [
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0.3024909,
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... |
Novel applications of diagnostic X-rays in activating a clinical photodynamic drug: Photofrin II through X-ray induced visible luminescence from "rare-earth" formulated particles. | In this communication we report on a novel non-invasive methodology in utilizing "soft" energy diagnostic X-rays to indirectly activate a photo-agent utilized in photodynamic therapy (PDT): Photofrin II (Photo II) through X-ray induced luminescence from Gadolinium Oxysulfide (20 micron dimension) particles doped with T... | 25,214,384 | [
-0.1638568,
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0.1485583,
0.1297107,
0.1372052,
0.04194109,
... |
Deconstructing Darwin: Evolutionary theory in context. | The topic of this paper is external versus internal explanations, first, of the genesis of evolutionary theory and, second, its reception. Victorian England was highly competitive and individualistic. So was the view of society promulgated by Malthus and the theory of evolution set out by Charles Darwin and A.R. Wallac... | 25,214,421 | [
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0.1000728,
0.06784592,
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0.2761742,
-0.2... |
The effects of gastrointestinal surgery on gut microbiota: potential contribution to improved insulin sensitivity. | Bariatric surgery induces weight loss and major improvement in insulin-resistance through many mechanisms some of which are weight independent. It is now well acknowledged that gut microbiota is involved in the development of obesity and its related metabolic diseases, at least in mice. However, its causal role in huma... | 25,214,424 | [
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0.09183641,
0.0368982,
0.09887515,
-0.4620094,
0.001538725,
-0.07839... |
Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I. | Inherited deficiencies of the L-lysine catabolic pathway cause glutaric aciduria type I and pyridoxine-dependent epilepsy. Dietary modulation of cerebral L-lysine metabolism is thought to be an important therapeutic intervention for these diseases. To better understand cerebral L-lysine degradation, we studied in mice ... | 25,214,427 | [
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0.2090004,
0.5685034,
0.08154322,
-0... |
Interface-induced chiral domain walls, spin spirals and skyrmions revealed by spin-polarized scanning tunneling microscopy. | The spin textures of ultra-thin magnetic layers exhibit surprising variety. The loss of inversion symmetry at the interface of the magnetic layer and substrate gives rise to the so-called Dzyaloshinskii-Moriya interaction which favors non-collinear spin arrangements with unique rotational sense. Here we review the appl... | 25,214,495 | [
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0.0640632,
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0.1491395,
0.02863496,
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The effects of training married men about premenstrual syndrome by pamphlets and short messages on marital satisfaction. | Premenstrual syndrome (PMS), which includes physical, psychological and emotional symptoms that occur during the luteal phase of the menstrual cycle, has a negative impact on the quality of the relationship among married couples. The purpose of the study was to examine the effects of educating married men by two method... | 25,214,514 | [
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0.282186,
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0.09834856,
0.01510064,
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0.002913958,
0.2750635,
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0.05859386,
0.2608757,
0.2372247,
0.02771646,
... |
Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death. | J-wave ECG patterns are associated with an increased risk of sudden arrhythmic death, and experimental evidence supports a transient outward current (I(to))-mediated mechanism of J-wave formation. This study aimed to determine the frequency of genetic mutations in genes encoding the I(to) in patients with J waves on EC... | 25,214,526 | [
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0.005421028,
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0.15685,
0.1386748,
0.1758042,
0.2908929,
-0.04731879,
0.368... |
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