title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
|---|---|---|---|
Synthesis of stereospecifically deuterated phenylalamines and determination of their configuration. | 1. Starting from trans-cinnamic acid a chiral (-)3-phenyl-[2,3-2H]propionic acid has been synthesized using Clostridium kiuyveri cells as catalyst. 2. The chiral dideuterated acid has been converted by chemical methods to a mixture of (2R) and (2S)-phenyl[2,3-2H]-alanine. 3. By means of 1H nuclear magnetic resonance sp... | 13,996 | [
-0.04252652,
-0.05919543,
0.004992631,
0.2760246,
-0.05282957,
-0.004932783,
-0.1838645,
0.4268778,
0.02483851,
-0.1542308,
0.08379029,
-0.4707645,
-0.0007825248,
0.1017287,
-0.7966582,
0.008882565,
-0.4054871,
0.4861032,
-0.2744689,
0.2744461,
0.1541505,
0.2357906,
-0.00... |
Carcinoembryonic character of gamma-glutamyltranspeptidase in primary hepatocellular carcinoma. | As a characteristic isoenzyme of gamma-glutamyl transpeptidase (gamma-GTP) has been detected in sera of patients with primary hepatocellular carcinoma, which migrates to alpha-globulin region on polyacrylamide-gel electrophoresis, biochemical studies on human fetal liver, Morris hepatoma (7316-A, 7794-A), and human hep... | 14,048 | [
-0.2710252,
-0.02941968,
-0.5423603,
-0.08381987,
0.08726183,
-0.09042366,
-0.5504931,
-0.1461536,
0.2013373,
0.3124855,
0.1282917,
0.1405357,
-0.1083944,
0.04732923,
0.05311416,
0.2490357,
-0.4145491,
0.028943,
0.2252403,
0.01683837,
0.5015694,
0.217501,
-0.2172579,
0.... |
Heartburn of pregnancy. | Lower esophageal sphincter pressure, basal gastric pH, fasting plasma gastrin, and plasma concentrations of estrone, estradiol, and progesterone were measured in pregnant volunteers at 12, 24, and 36 weeks of gestation, and again at 1 to 4 weeks postpartum. In addition, basal and pentagastrin-stimulated acid secretory ... | 14,050 | [
-0.354194,
0.1710886,
-0.171462,
-0.0216658,
0.003090597,
-0.2652294,
-0.04637,
-0.2851512,
0.1368388,
0.1399356,
0.3484219,
0.07340486,
-0.005292492,
-0.3642051,
-0.07464211,
-0.1106666,
-0.2954755,
-0.1404593,
-0.05270281,
-0.04423608,
0.1449269,
0.2947722,
0.09879934,
... |
[Synthesis of norepinephrine from 3,4-dihydroxyphenylserine by L-aromatic amino acid decarboxylase of the rat brain and kidneys]. | The enzymic decarboxylation of stereoisomers of DOPS was examined using rat brain and kidney decarboxylase. Optimal assay conditions for racemic threo- and racemic erythro-DOPS decarboxylation were determined by the experiments concerning 1) time course, linear for 20 min, 2) optimal pH, pH 8.2, 3) optimal temperature,... | 14,060 | [
-0.1240497,
0.08224718,
-0.559072,
0.01311485,
0.1666997,
-0.1409728,
-0.3355217,
-0.24034,
0.153131,
-0.2159194,
0.2280625,
0.289297,
0.129823,
0.1077247,
-0.9089493,
0.08668868,
-0.6711743,
0.2163579,
0.04670422,
0.5142079,
0.4786184,
0.3787966,
-0.3689211,
0.05312124... |
[Paroxysmal alveolar hypoventilation syndrome (author's transl)]. | The case of a 42-year-old female patient with central disturbance of respiration was reported which, contrary to the previously described forms of central alveolar hypoventilation, could be characterized by paroxysmal-like apnoic conditions without any feeling of suffocation. Clinically, initial cardiopulmonary complic... | 14,066 | [
-0.00542749,
0.01588867,
-0.02873221,
-0.1932024,
0.008292519,
-0.1473268,
-0.177197,
-0.3395662,
0.0528948,
-0.02339222,
0.01421646,
0.07456778,
0.02281149,
-0.198736,
-0.3236836,
0.02495119,
-0.4084924,
0.1528207,
0.1863828,
0.1697179,
-0.01248896,
0.3004003,
0.08819613... |
Isolation of an Escherichia coli mutant deficient in thioredoxin reductase. | A mutant of Escherichia coli defective in thioredoxin reductase has been isolated and partially characterized. This mutant has no detectable thioredoxin reductase activity in vitro and yet it exhibits no in vivo defect in reduction of ribonucleotides. Evidence is presented that indicates that, in cells permeabilized vi... | 14,115 | [
-0.1581906,
-0.08073201,
-0.1715351,
-0.08364669,
-0.06940773,
0.01516571,
-0.1142467,
-0.1252728,
0.019619,
-0.09887657,
0.4293419,
0.3297623,
0.07677047,
0.2790536,
-0.3253475,
0.07856068,
-0.3879631,
-0.1132101,
-0.1764244,
0.01270335,
0.2061806,
0.09900437,
-0.0503575... |
Dog renal kallikrein: purification and some properties. | The contents of kallikrein [EC 3.4.21.8] in the kidneys of various animals were estimated and the activity was found to be most potent in dogs. The dog renal kallikrein (DRK) was located mainly in the kidney cortex. Following the activation of a dog kidney cortex homogenate with acetone, kallikrein was purified about 2... | 14,121 | [
0.143938,
0.320643,
0.1587664,
-0.2920316,
0.1791971,
-0.08864082,
0.248202,
-0.2316205,
-0.1704581,
-0.01943396,
-0.0871731,
0.2222812,
-0.07342436,
-0.3424109,
-0.4554281,
0.2365457,
-0.7894446,
0.4236075,
0.4824303,
0.06714517,
0.1925653,
0.2641766,
-0.3244655,
0.086... |
A novel neutral protease(s) from monkey liver. | A novel neutral protease(s), which is presumably membrane-bound, was found in monkey liver using heat-denatured casein as a substrate and was separated from other major catheptic proteases by successive procedures of gel filtration on Ultrogel AcA 22, solubilization by deoxycholate and gel filtration on Sepharose 6B. T... | 14,127 | [
-0.1279469,
-0.06785155,
0.07424711,
-0.01067854,
-0.04614142,
0.02055736,
-0.1138129,
0.1340679,
0.2730645,
0.02199876,
0.1505152,
0.2396246,
0.2300719,
-0.002295315,
-0.2165978,
-0.1642304,
-0.4863085,
-0.1079834,
-0.03579082,
0.294943,
-0.04509018,
-0.06475198,
-0.3778... |
A new large form of transcarboxylase with six outer subunits and twelve biotinyl carboxyl carrier subunits. | A new form of transcarboxylase has been isolated which has a molecular weight of 1,200,000, an s20,w of 26 S, and contains 12 biotinyl groups. Transcarboxylase as isolated previously has a molecular weight of 790,000, an s20,w of 18 S, and contains six biotinyl groups. The larger species of enzyme consists of a central... | 14,153 | [
-0.2759003,
0.1632891,
0.07430509,
-0.1783008,
-0.1758466,
-0.3785827,
-0.1104986,
0.2598847,
0.29363,
0.02816653,
0.01601213,
0.03030582,
0.2531744,
0.1130206,
-0.4876701,
0.2495199,
-0.3808565,
0.006067066,
-0.01348909,
0.232307,
-0.08232717,
0.1596705,
-0.1067263,
0.... |
Surface localization of 5'-nucleotidase on the mouse lymphocyte. | The optimal conditions for the cytochemical localization of 5'-nucleotidase (AMPase) in the mouse lymphocyte have been established. Quantitative monitoring of the effects of fixation and the components of the cytochemical medium showed that the cytochemistry can be performed under conditions that do not lead to loss of... | 14,210 | [
-0.1275233,
-0.4058447,
-0.5237127,
0.07733505,
0.1366709,
-0.2029101,
0.03684782,
0.07235513,
0.1228487,
0.1533743,
0.02459178,
0.1839176,
0.1286941,
0.3043956,
-0.1749064,
0.2173921,
-0.6310155,
-0.2718748,
-0.1664512,
0.6217637,
0.2529829,
0.1176244,
-0.209238,
-0.03... |
Delayed initiation of SS1 pulses in the sea anemone Calliactis parasitica: evidence for a fourth conducting system. | 1. Single electrical shocks to the column sometimes elicit a series of 1-6 pulses in the SS1 (ectodermal slow system) but the first pulse does not appear until 5-28 s after stimulation. These pulses occur in addition to the early SS1 pulse which follows every shock and which has a conduction delay of less than 1 s. 2. ... | 14,219 | [
-0.334374,
-0.4396856,
-0.212588,
-0.2250883,
-0.04153302,
-0.2856445,
-0.3373116,
-0.1789308,
-0.0810553,
0.2981177,
-0.05634383,
-0.0523561,
-0.02937571,
-0.2704682,
-0.232875,
-0.3533047,
-0.507524,
-0.213806,
-0.05985289,
-0.1930191,
0.5649503,
0.1568701,
-0.02636641,... |
Correlation of structural transitions in coliphage R17 with its loss of infectivity. | A circular dichroism comparative study of isolated and in situ phage R17 RNA reveals in both cases the same degree of base pairing. However, thermal circular dichroism melting profiles exhibit the presence of free energy of interaction between RNA and capsid protein. It is apparent that the capsid stabilizes the RNA st... | 14,222 | [
-0.3342325,
0.294975,
-0.471695,
0.04920007,
-0.03624384,
-0.05980721,
-0.1340306,
-0.157533,
-0.06463978,
-0.03623029,
0.118268,
-0.1743845,
0.2099324,
0.01254939,
-0.4536207,
-0.03888068,
-0.287254,
-0.09466667,
-0.169467,
0.04531949,
0.5011606,
-0.2174553,
0.1171731,
... |
The use of tris-HCl buffer for inoculation of tomato protoplasts with tobacco mosaic virus. | When tris-HCL was used as the buffer for inoculation of tomato protoplasts with tobacco mosaic virus, a greater proportion became infected than when phosphate was used. Using 0-05 M-tris-HCl buffer, pH 8-0, in the presence of poly-L-ornithine or poly-D-lysine, 50 to 80 % infection was obtained. | 14,223 | [
0.1273189,
-0.169915,
-0.1110887,
0.1217124,
0.06604222,
-0.1684551,
0.1424951,
-0.0857024,
-0.3793493,
-0.1695171,
0.1471185,
0.561681,
-0.07701562,
0.2935381,
-0.2633455,
0.04461137,
-0.2464135,
0.1216891,
-0.004777606,
-0.003989129,
0.4333846,
0.4305426,
-0.1493848,
... |
Traditional versus individualized nursing instruction: comparison of State Board Examination scores as a result of these two methods of nursing instruction. | There is no evidence as a result of this study to preclude that the LEGS Program is not worthwhile. Achievement of State Board Examination Scores have not suffered as a result of this method of instruction, at least in the three schools studied. Statistically, there is no significant difference in mean achievement of S... | 14,227 | [
0.02152966,
0.3631717,
-0.1815775,
-0.1151846,
0.1482297,
-0.1057292,
0.04338269,
-0.2856933,
-0.3636574,
-0.0663752,
0.07806356,
0.1551604,
-0.01218089,
-0.1697449,
-0.2059591,
-0.1949872,
-0.6793143,
0.08011275,
-0.4589684,
0.07138332,
0.19317,
0.2377679,
0.177215,
0.... |
The effects of feeding on arterial blood gases and lung mechanics in newborn infants recovering from respiratory disease. | Fifteen infants recovering from neonatal respiratory disease had arterial blood gases and lung mechanics measured 5 minutes before bolus feeds and at 5, 10, 20, and 30 minutes after feeding to determine physiologic effects of feeding. PaO2 fell significantly from prefeeding values at 5, 10, and 20 minutes after feeds. ... | 14,240 | [
-0.2173914,
-0.229353,
-0.693059,
-0.1575596,
0.007424793,
-0.2602322,
0.1133507,
-0.03173426,
-0.1314634,
-0.02561576,
0.3286386,
-0.07321727,
-0.409125,
-0.277289,
-0.1958008,
-0.1841089,
-0.07652747,
0.2531632,
-0.136303,
-0.03121133,
-0.05484881,
-0.05711664,
-0.08933... |
[Perspectives of use of genetic methods of control of bloodsucking Diptera - vectors of the diseases of man]. | This paper presents genetic methods of control of bloodsucking Diptera, mosquitoes. The perspective of the use of various control methods, first of all those tested under field conditions in application for bloodsuckers which are of medical importance throughout the USSR, is regarded. The opinion is suggested that the ... | 14,323 | [
-0.04858281,
0.1368248,
0.3166658,
-0.283628,
0.1024132,
-0.3061954,
-0.1019973,
-0.003539818,
0.2430313,
0.1523857,
0.3175593,
-0.1470277,
-0.06848046,
0.02195891,
-0.8141314,
-0.3855795,
-0.2113177,
-0.05030618,
-0.2018644,
0.1092565,
0.2657303,
0.1396923,
-0.2332592,
... |
High-dose treatment with neuroleptics in the acute phase of mental disease. | More than 300 patients have been observed during treatment with either flupenthixol, haloperidol, fluphenazine enanthate or perphenazine enanthate in high doses, whilst suffering from severe mental disease, usually of psychotic nature. Used correctly, high-dose treatment gives a rapid control of psychotic symptoms, an ... | 14,332 | [
-0.1715525,
0.07872625,
-0.3334319,
-0.2657904,
0.3373681,
-0.233169,
-0.171847,
-0.1276958,
-0.3929245,
0.07290491,
0.03427498,
-0.0728417,
-0.05665307,
0.06006334,
0.02601474,
0.1068485,
-0.3071714,
0.2244011,
0.2280184,
0.2691513,
-0.1192814,
0.3991807,
-0.1542796,
-... |
Analgesic, heart rate, and temperature effects of delta8-THC during acute and chronic administration to conscious rats. | Acute and chronic effects of delta8-THC on tail-flick, heart rate, and rectal temperature responses in conscious, unrestrained male rats were studied. In the acute experiment unidirectional dose-dependent analgesic, hypothermic, and negative chronotropic cardiac effects were observed within the dose range employed. Of ... | 14,347 | [
-0.09056658,
-0.1900893,
-0.5645214,
0.03238646,
0.1114346,
-0.3317272,
-0.265339,
0.09882386,
-0.1416662,
-0.5940707,
0.2236278,
0.5095129,
0.165289,
0.1215,
0.06956828,
-0.3258196,
-0.5399629,
0.1508389,
-0.1751651,
0.1150685,
-0.005604911,
0.1287067,
-0.2418979,
0.39... |
The role of brief hypocapnia in the ventilatory response to CO2 with hypoxia. | In conscious cats the ventilatory response curve to physiological range of CO2 is displaced upward by hypoxia (about 45 torr), but it rises, either parallel with, or convergent on, the normoxic curve. Thus, a positive interaction of hypoxia and hypercapnic stimuli is not observed under these circumstances. However, if ... | 14,364 | [
-0.09581602,
-0.01188257,
-0.1346516,
-0.2108005,
0.4306013,
-0.1391166,
-0.139489,
-0.1121358,
-0.1354704,
0.1166451,
-0.1614708,
0.2147443,
-0.07845207,
-0.1101813,
0.1278138,
-0.2338123,
-0.3676547,
0.3293707,
0.000564778,
0.0613741,
-0.1270472,
0.09948926,
0.1853295,
... |
The CSF HCO3 increase in hypercapnia relationshp to HCO3, glutamate, glutamine and NH3 in brain. | To study the role of carbonic anhydrase in the CSF [HCO3] increase in respiratory acidosis and its effect on brain ammonia, anesthetized rats were subjected to hypercapnia (7% CO2) for 2 hours. The animals received periodic intraventricular injections of either 'mock' CSF or 'mock' CSF and acetazolamide for 45 minutes ... | 14,366 | [
-0.2664621,
-0.005467565,
-0.4602334,
0.07376555,
0.3376496,
-0.0284868,
-0.1895185,
-0.04455431,
-0.5898855,
0.1557767,
0.1611772,
0.6232517,
-0.02215875,
-0.2014805,
0.01914561,
0.07371397,
-0.2529285,
0.2448967,
0.1407388,
-0.02024573,
-0.2126199,
0.1569553,
0.2445475,... |
Oral complications in anorexia nervosa. | Anorexia nervosa (AN), a psychosomatic disease mainly affecting young women, is characterized by conscious starvation, periods of excessive carbohydrate intake and often deliberate vomiting. Medical history, dental examination, and saliva tests of 39 patients aged 14 to 42 years, having suffered from AN for periods of ... | 14,394 | [
-0.3400339,
0.0191281,
0.2469424,
0.1108261,
0.148017,
-0.0355479,
0.09188221,
-0.1886314,
0.04764753,
0.1038273,
0.1946548,
0.2743402,
-0.1108589,
0.08104278,
-0.1614156,
0.1220771,
-0.2441589,
0.1732322,
0.006287943,
-0.09187853,
0.2060374,
0.1779349,
-0.1815784,
0.03... |
Massive skeletal trauma in renal transplant patients. | A review of 251 renal transplants done at the Vanderbilt University Medical Center since October 1962 revealed three patients who had suffered subsequent skeletal injuries sufficient to cause hospitalization. In a 37-year-old woman, a closed fracture of the pelvis healed satisfactorily in the usual period of time. In a... | 14,401 | [
-0.2302998,
0.07370146,
-0.2395904,
-0.1748502,
0.01064905,
-0.1731743,
-0.3098235,
0.2869403,
0.1494777,
0.01390276,
0.2916637,
-0.2252359,
-0.2216647,
0.009678233,
-0.2830031,
0.06224341,
-0.04456154,
0.006792877,
0.02182987,
-0.02971216,
0.01312389,
0.1861353,
-0.03909... |
[Gamma-glutamyltranspeptidase in chronic polyarthritis. II. Influence of drugs]. | Thirty outpatients with active RA were treated with Sudoxicam, a nonsteroidal antirheumatic drug, for periods of 6-10 months. Gamma-GT, alkaline phosphatase and transaminase were estimated at 2 week intervals. During treatment, the frequently elevated values showed a significant tendency towards normality (time trend a... | 14,456 | [
0.1297718,
-0.1777881,
-0.3754165,
0.1421205,
0.05820529,
-0.1714037,
-0.0006018546,
0.09028324,
-0.3484559,
-0.198177,
0.01513525,
-0.04103646,
0.3338632,
0.203409,
-0.213695,
0.182424,
0.01615342,
0.1138098,
0.1903,
0.3902572,
-0.1042955,
0.00969771,
-0.4163727,
-0.03... |
Infantile periarteritis nodosa or mucocutaneous lymph node syndrome. A report on four cases and diagnostic considerations. | Coronary artery aneurysm in childhood is a rare disease and has in most cases been ascribed to infantile periarteritis nodosa (IPN). In recent years a mucocutaneous lymph node syndrom (MLNS) has been found almost exclusively in Japan first described by Kawasaki 1967; this disease frequently involves the coronary arteri... | 14,473 | [
-0.3860221,
-0.4170354,
-0.3913513,
-0.3809048,
-0.00167351,
-0.2490238,
-0.2306765,
-0.1078301,
0.1074625,
-0.01984687,
-0.09271087,
-0.2586491,
0.08207736,
-0.09250098,
-0.2320648,
-0.1899622,
-0.5474989,
-0.001669299,
0.2165494,
0.3302065,
0.4865671,
0.06309906,
-0.171... |
Salivary Secretion in wild Glossina pallidipes Austen. (Diptera, Glossinidae). | The salivation behaviour of wild G. pallidipes obtained from Lambwe Valley and Kbwezi was studied. Salivation was measured by counting the number of salivary drops secreted per minute and measuring the sizes of the stained saliva after drawing them with a camera lucida. The results confirmed observations obtained from ... | 14,492 | [
0.1896466,
-0.03279514,
-0.3412435,
0.034032,
0.1948618,
-0.3839301,
0.08648372,
-0.2761485,
0.0225661,
-0.1458446,
0.2701602,
0.06212267,
-0.02914753,
-0.3243142,
-0.1189565,
-0.06218286,
-0.5144919,
0.004432107,
0.2318631,
-0.1225675,
0.3311036,
0.3260615,
-0.04545679,
... |
The essential action of propranolol in hypertension. | The unique action of propranolol and other beta blockers in lowering raised arterial pressure is discussed. Although the onset of the antihypertensive effect is not immediate, many trials have confirmed the efficacy of these drugs. Animal experiments have thrown little light on the mechanism of action of beta blockers ... | 14,498 | [
-0.1963779,
0.07975245,
-0.554926,
-0.1673453,
0.1448202,
-0.4987689,
-0.2757151,
-0.1387053,
0.2014271,
-0.2355008,
-0.2091095,
-0.09749066,
0.1141954,
-0.1878445,
-0.2110811,
0.07738648,
-0.5806243,
0.1034431,
-0.05568362,
0.3705191,
-0.1976164,
0.1546585,
0.0280895,
... |
Renin and aldosterone secretion in pheochromocytoma. Effect of chronic alpha-adrenergic receptor blockade. | Patients suffering from pheochromocytoma characterized by an exclusive or almost exclusive excess of norepinephrine showed no (one patient) or only a moderate increase (two patients) in renin and aldosterone secretion. In those three patients with concomitant distinct hypersecretion of epinephrine, renin release (and a... | 14,500 | [
-0.08744194,
-0.00224915,
-0.6751201,
-0.2839411,
0.09862851,
-0.5355076,
-0.04083925,
0.03455921,
0.08886968,
0.2175115,
-0.2133924,
0.2415818,
-0.01868322,
-0.07256348,
-0.1651978,
-0.1574523,
-0.1891545,
0.007543085,
0.1150886,
0.06692122,
0.1948389,
0.1868158,
-0.0655... |
Different antihypertensive effect of beta-blocking drugs in low and normal-high renin hypertension. | The treatment response to beta-adrenoceptor blocking drugs was compared in two groups of patients with primary (essential) hypertension and different renin levels. Each group consisted of 25 patients and was equally distributed regarding age, severity and stage of hypertension. In the first group (group 1), the mean up... | 14,504 | [
-0.1632488,
0.09046458,
-0.3847557,
-0.3240333,
0.003886304,
-0.5511597,
-0.1010155,
-0.06068464,
-0.001740564,
0.02865651,
0.0432418,
0.3130628,
0.09722791,
-0.1119018,
-0.5910004,
-0.1448012,
-0.1960964,
0.3530463,
-0.01120023,
0.4486476,
0.1970654,
0.3492689,
0.0038876... |
A smooth muscle active factor isolated from renal cortex of the rabbit. | Homogenates of rabbit renal cortex contained a water-soluble material with striking activity on smooth muscle derived from the rabbit aorta, rat stomach, and guinea pig ileum--but not rat colon or chick rectum. Evidence derived from the spectrum of its pharmacologic activity, the influence of specific competitive antag... | 14,508 | [
-0.04669408,
-0.100376,
-0.2842201,
-0.2823772,
0.4399667,
-0.3547348,
-0.1808916,
0.007129985,
0.1688837,
-0.1882958,
0.1438538,
-0.1939683,
0.3881559,
-0.1718256,
-0.6343617,
0.1653037,
-0.7736208,
-0.01720862,
0.3841444,
0.5091552,
0.2519912,
0.1460728,
-0.2025853,
0... |
[Effect of run-training and run-stress on glucose assimilation and insulin release in rats of different age (author's transl)]. | 82 male rats of different age have been investigated after a definitive run-training, after a run-training with subsequent run-stress and after a run-stress without run-training. An intravenous glucose tolerance test has been done measuring glucose and insulin serum levels before and after i.v. glucose application. Dat... | 14,518 | [
-0.05541356,
0.009721087,
-0.2078965,
0.01603546,
0.09610936,
-0.4507037,
-0.02415581,
0.04860038,
-0.1101311,
0.1719182,
-0.007118175,
-0.4677973,
0.009242618,
-0.3045578,
-0.5081361,
-0.4595239,
0.05431782,
0.4069076,
0.0662572,
0.3625147,
0.07492869,
0.0756792,
-0.0131... |
[Geriatric change of thyroid function and thyroid diseases (author's transl)]. | The geriatric changes of thyroid function in healthy individuals are relatively low; therefore it is not necessary to take it into consideration for routine diagnostic work. Thyroid diseases show an increase with age and also a change of the clinical picture. Therefore, and because of being superimposed by symptoms of ... | 14,521 | [
-0.1841467,
-0.2532497,
-0.04552878,
-0.1111492,
0.01919165,
-0.1889168,
-0.1653964,
-0.00533361,
0.08804607,
0.2340264,
0.1721997,
0.3170583,
-0.2068903,
-0.1142147,
-0.2402435,
0.1413587,
-0.1514246,
0.1449795,
0.005351911,
0.267866,
0.359629,
0.247253,
-0.05974403,
0... |
[Paranoid syndromes in the involution (author's transl)]. | Conditions of outbreak and chronification of paranoid syndromes, including the existence of an "axial syndrome" and behaviour theories are hypothetically summarized. The individual characteristics of patients with the first paranoid symptoms during involution appear to depend mainly on three factors: the theme of the d... | 14,525 | [
-0.2803319,
-0.1191093,
0.04202226,
-0.1592776,
-0.09924261,
-0.3867627,
-0.1651778,
-0.2252941,
-0.004618447,
0.3264203,
-0.066649,
-0.3052857,
-0.1442778,
0.01144992,
-0.07393028,
-0.05332758,
-0.2489298,
0.1271696,
0.07435613,
-0.05745513,
0.2237967,
0.3291313,
-0.1244... |
[Patients and their diseases in a geriatric hospital (author's transl)]. | Report on patients and their problems of a hospital of chronic diseases. Geriatric departments, part of clinics of acute diseases should treat not only patients without real chance for rehabilitation or discharge. Most of the diseases of elder persons are such of the arterial system, especially of the cerebral and coro... | 14,542 | [
0.05866917,
-0.0843652,
0.01544437,
0.1928463,
0.2836766,
-0.1964196,
-0.01088409,
-0.07731611,
-0.273659,
0.1585265,
0.1173899,
-0.06152556,
-0.09150518,
-0.3384639,
-0.2952099,
-0.07770906,
-0.3741865,
0.4973174,
-0.1651586,
0.127679,
0.07970008,
-0.1061392,
0.1783141,
... |
[Indications for orthopedic procedures in old people (author's transl)]. | Advancements in general medicine and anesthesiology have enabled surgical procedures in old people with diminished risks. With reference to special problems the absolute indication for orthopedic procedures particularly for the old can be demonstrated. | 14,544 | [
-0.06916974,
0.01064415,
-0.07629711,
0.0710289,
-0.1693503,
-0.1170407,
-0.2775619,
0.05339207,
-0.1839989,
-0.07058274,
0.2504739,
-0.02497836,
0.1828009,
-0.3264354,
-0.3374849,
-0.01236295,
-0.3419597,
0.2534654,
-0.2170399,
0.3275935,
0.3404642,
0.05436209,
-0.000846... |
[Chromosomal investigations in two age groups of human females]. | Chromosomal analysis was performed in cultured lymphocytes from 32 old (ages 76-85, abbr. A) and 31 young (ages 15-20, abbr. J) patients, who were representative for a great part of the "normal" female population of the same age. In regard to culture time (48 and 72 hours) each age group was divided into two halves; 15... | 14,549 | [
0.005094081,
-0.4852595,
0.01895114,
0.2557616,
0.2933305,
-0.1178756,
-0.4717164,
0.326856,
0.4832457,
0.3139436,
0.2048292,
0.2525341,
-0.01706191,
0.1100995,
-0.820582,
-0.5392054,
-0.02985756,
-0.0650005,
-0.1568702,
0.1741625,
0.4819165,
0.07787863,
-0.2971142,
-0.... |
[Place of neuroleptics in geriatric anesthesia]. | The elderly show changes in various parenchymas linked to the process of ageing. Pathological abnormalities may be added to this picture leading to physiopathology peculiar to the aged. In relation to special problems raised by this background, the advantages and disadvantages of N.L.A. are discussed. The authors refer... | 14,566 | [
0.2275318,
-0.2331016,
-0.1421874,
-0.08207595,
0.06377086,
0.002031846,
-0.2857337,
-0.2564933,
-0.3305193,
0.08650071,
-0.04900382,
0.3558054,
0.1201339,
0.08978162,
-0.3667542,
-0.1038017,
-0.2331883,
0.1589256,
0.2511088,
0.450117,
0.2694894,
-0.03227554,
0.03518674,
... |
[Place of neuroleptics in neurosurgical anesthesia-resuscitation]. | The interest of neuroleptics in neurosurgery should be examined in the light of physiopathological and pharmacological data concerning cerebral circulatory autoregulation and intracranial pressure. The fairly favourable conclusions permit one to consider their wide use justified, especially, by the feeble hypnogenic ef... | 14,570 | [
0.05424086,
0.00666762,
-0.2245943,
-0.5191153,
0.09758518,
-0.2234568,
-0.3767861,
-0.21989,
-0.05070753,
0.08914625,
0.134647,
0.3047516,
0.102217,
-0.1745887,
-0.2466705,
0.06198113,
-0.4112222,
0.3076552,
0.1271434,
0.2039528,
0.08314411,
-0.03223902,
-0.07861299,
0... |
[Very-high-dose droperidol and brain stem injuries]. | Treating four comatose children with severe injuries of the brain stem, suffering from severe autonomic disorders without any indications for neurosurgery, we were led to increase gradually the doses of neuroleptics used as basis of treatment, the main one being Droperidol. The increase in dosage, often reaching very h... | 14,571 | [
-0.08014888,
-0.2077229,
0.1736189,
-0.253367,
0.1960362,
-0.1485432,
-0.3684782,
0.007753414,
-0.1521359,
0.1675236,
0.1113248,
0.3244808,
-0.118459,
0.08939983,
-0.4060293,
-0.3037838,
-0.1025203,
0.01024088,
-0.06035929,
0.4672166,
-0.02893035,
-0.1221107,
0.01176187,
... |
Comparison of thiopentone versus althesin for caesarean section. | Thiopentone and Althesin were compared in 50 patients undergoing general anaesthesia for Caesarean section. The patients were divided into group A (24 mothers) were thiopentone (3.5 mg/kg) was used for induction and group B (26 mothers) where Althesin (80 mu1/kg) was employed. Blood samples for estimating the maternal ... | 14,588 | [
-0.2286427,
-0.04588766,
-0.6749274,
0.05262604,
0.1585191,
-0.2653811,
-0.6325826,
-0.2749233,
-0.03013364,
-0.1281779,
0.02398532,
0.3637297,
0.01841252,
-0.1770261,
-0.2395006,
-0.3464811,
-0.4607781,
0.05433236,
-0.1423618,
0.3591975,
0.233784,
0.3612404,
-0.01097745,... |
An experimental and clinical pharmacological study of the influence of triamterene on the diuretic and saluretic properties of furosemide xantinol. | The diuretic and saluretic effect of furosemide xantinol administered alone and mixed with different amounts of 2,4,7-triamino-6-phenylpteridine (triamterene) have been investigated in rat and man. The presence of triamterene resulted in a dose dependent inhibition of furosemide xantinol induced diuresis in both specie... | 14,648 | [
-0.2090501,
0.0737588,
-0.1222063,
0.01291936,
0.3588747,
-0.1371332,
-0.3177679,
0.1028023,
-0.04836312,
-0.02172956,
0.13245,
0.07864274,
0.01261564,
-0.2031038,
-0.4620004,
-0.07094418,
-0.01219804,
0.1290417,
-0.2332104,
0.3051028,
0.2525985,
-0.1917345,
-0.1069868,
... |
Biosynthesis of spin-labeled peptidoglycan: spin-spin interactions. | Membrane preparations from Gaffkya homari catalyzed the in vitro biosynthesis of soluble uncross-linked spin-labeled peptidoglycan, a uniformly labeled polynitroxide, from the spin-labeled nucleotide UDP-MurNAc-Ala-DGlu-Lys(Nepsilon-2,2,5,5-tetramethyl-1-pyrrolin-1-oxyl-3-carbonyl)-DAla-DAla (I) and UDP-GlcNAc. Soluble... | 14,677 | [
0.3257367,
-0.332519,
-0.01604421,
0.1075169,
-0.1498106,
-0.221701,
-0.03732513,
0.06013481,
0.216212,
0.1366138,
-0.1488736,
-0.005469215,
0.2995212,
-0.007637152,
-0.5773804,
-0.0371673,
-0.6146992,
0.1254108,
-0.07912297,
0.2078027,
0.5436588,
-0.2250022,
-0.1334795,
... |
Selective chemical modification of Escherichia coli elongation factor G: butanedione modification of an arginine essential for nucleotide binding. | Treatment of Escherichia coli elongation factor G with the arginine reagent, 2,3-butanedione, leads to the inactivation of the enzyme when performed in sodium borate buffers. The inhibition follows pseudo-first-order kinetics until 95% of the activity has been lost and further incubation results in complete inhibiton. ... | 14,679 | [
-0.05565218,
0.2149885,
-0.2669469,
0.3100266,
0.1982758,
-0.06603099,
0.1188388,
0.1922114,
0.0799814,
0.1495808,
0.1035123,
-0.1178327,
-0.02255131,
0.1345955,
-0.1480636,
0.2075915,
-0.2266402,
-0.03641392,
-0.03914739,
0.4151,
0.276061,
0.15634,
-0.06843872,
0.08832... |
Separation of DNA-dependent DNA polymerase activities in Micrococcus radiodurans. | DNA polymerase activities in Micrococcus radiodurans were separated into two fractions after purification more than 2000 fold. They differ in pH optimum and residual activities in the absence of a full deoxyribonucleoside triphosphates complement. NAD partly inhibited one of the activities. Both activities were eluted ... | 14,686 | [
-0.2450485,
-0.07877373,
-0.1500616,
-0.01555257,
0.09137218,
-0.3119697,
-0.2576362,
-0.1503432,
0.2737907,
0.2137036,
0.1632409,
-0.1075821,
0.002994579,
0.1918934,
-0.5239345,
0.0704843,
-0.1676778,
-0.003474843,
-0.3323312,
0.2835278,
0.4657928,
-0.3082881,
-0.0079600... |
Iodination-deiodination. A radiochemical method for detection of structure and changes in structure in RNA. | Bound iodine is released from radioiodinated nucleotides in polymers exposed to sodium bisulfite. The rate of bisulfite-catalyzed deiodination of pyrimidines can be controlled both by change of temperature of pH and is also dependent on the molecular association of the nucleotide. The rate of release of iodine from iod... | 14,687 | [
-0.1357733,
0.240411,
-0.03928909,
0.1012836,
0.1142466,
-0.3651262,
-0.2693384,
0.1308395,
0.2628269,
0.1170911,
0.1973325,
-0.09625139,
0.09104809,
0.1534424,
-0.0009651692,
-0.1879693,
-0.0326896,
0.016823,
-0.1780315,
0.1618418,
0.1859635,
-0.04273484,
-0.02629484,
... |
Sulphur metabolism in Paracoccus denitrificans. Purification, properties and regulation of serine transacetylase, O-acetylserine sulphydrylase and beta-cystathionase. | 1. Serine transacetylase, O-acetylserine sulphydrylase and beta-cystathionase were purified from Paracoccus denitrificans strain 8944. 2. Serin transacetylase was purified 150-fold. The enzyme has a pH optimum between 7.5 and 8.0, is specific for L-serine and is inhibited by sulphydryl-group reagents. The apparent Km v... | 14,692 | [
-0.1433244,
-0.3372718,
0.03640461,
-0.1880723,
-0.3096256,
0.1391808,
0.05789766,
0.0943567,
0.07424892,
-0.2115899,
-0.02670787,
0.3035632,
0.1659386,
0.1922716,
-0.5955473,
0.004362344,
-0.5028681,
0.2341578,
0.3476916,
0.3945619,
-0.01491637,
0.06511512,
-0.08643149,
... |
Sulphur metabolism in Paracoccus denitrificans. Purification, properties and regulation of cysteinyl-and methionyl-tRNA synthetase. | Cysteinyl- and methionyl-tRNA synthetases (EC 6.11.-) were purified 1200- and 1000-fold, respectively, from sonic extracts of Paracoccus denitrificans strain 8944, and kinetics, substrate specificity and regulatory properties were determined using the ATP-PPi exchange reaction. Both enzymes had pH optima of approx. 8 a... | 14,693 | [
-0.2257594,
-0.1476794,
0.1872948,
-0.06084792,
0.0209444,
-0.1160476,
-0.07421402,
0.007233619,
0.1173298,
-0.04990705,
-0.1202644,
0.1339509,
0.006103592,
0.2407839,
-0.3902561,
0.2968028,
-0.5666546,
0.06953312,
-0.1255973,
0.4227137,
0.2352846,
0.05863366,
-0.01923474... |
The rate of reaction between cytochrome C peroxidase and hydrogen peroxide is not diffusion limited. | The apparent biomolecular rate constant for the cytochrome C peroxidase (EC 1.11.1.5)-hydrogen peroxide reaction has been measured as a function of temperature between 5 and 25 degree C at pH 4,5.5, and 7 and as a function of viscosity over a fifteen-fold range. From the independence of the rate constant on the viscosi... | 14,694 | [
-0.2848319,
-0.1902425,
-0.3005978,
0.2395156,
0.02785327,
-0.08519045,
-0.02077622,
0.00999347,
0.1347476,
0.04565725,
0.09014333,
0.2244633,
0.1367128,
0.1724405,
-0.1285358,
-0.2903084,
-0.389239,
0.1952932,
0.1083042,
0.05586299,
0.4160574,
0.01744884,
0.1317779,
0.... |
[Isolation and some properties of Ca2+-, Mg2+-dependent deoxyribonuclease from sea urchin (Strongylocentrotus intermedius) embryos]. | Ca2+-Mg2+-dependent deoxyribonuclease (deoxyribonucleate-5'-oligonucleotidehydrolase E. C. 3.1.4.5). Molecular weight of the enzyme is found to be 40 000 daltons isoelectric point--4.4. The enzyme degraded DNA only in the presence of bivalent cations. It hydrolyses preferentially native DNA with pH optimum 7.0-7.2 in t... | 14,721 | [
0.02501552,
-0.1265788,
-0.1188683,
0.006239359,
0.04105894,
-0.06053086,
-0.1699644,
0.137156,
0.2506102,
0.1542031,
-0.1267577,
0.2185355,
-0.1908607,
0.1359409,
-0.7073203,
0.005278277,
-0.4044302,
0.0816745,
0.07513694,
0.4128998,
0.5018336,
0.3111528,
-0.3164113,
0... |
Isolation and properties of a ferredoxin from leaves of Sambucus racemosa L. | Ferredoxin was isolated in good yield from leaves of Sambucus racemosa L. by the following procedure: (1) homogenization in buffered acetone-water (1:1v/v); (2) ion-exchange chromatography on several columns of DEAE-cellulose; and (3) purification by gel filtration with Sephadex G-75. The ultraviolet and visible spectr... | 14,775 | [
-0.1234381,
0.04580154,
-0.3297436,
0.1632926,
0.09315046,
0.08560709,
0.04036578,
-0.3660487,
-0.05162589,
-0.200805,
-0.1105505,
0.1502603,
0.1283819,
0.0379771,
-0.2279535,
0.08971021,
-0.2343046,
0.2576325,
0.3258313,
0.2003157,
0.3607403,
0.4993865,
-0.290152,
0.25... |
Evoked release from guinea pig cerebral cortex slices of endogenous 14C-labelled amino acids, labelled via D-[U-14C]glucose. | Release of endogenous amino acids labelled via D-[U-14C]glucose was compared with that of several exogenous labelled amino acids using slices of guinea pig cerebral cortex. Electrical field stimulation evoked a selective release of endogenous [14C]glutamate, [14C]aspartate, and gamma-amino[14C]butyrate (14C-labelled GA... | 14,778 | [
0.03569148,
-0.0324025,
-0.3068763,
0.0822739,
0.3358854,
-0.4304925,
-0.03048281,
0.004258622,
-0.1264052,
0.1185463,
-0.1750982,
-0.07387512,
0.06807103,
-0.04114554,
-0.2998018,
-0.03542231,
-0.5661156,
0.2635864,
-0.003668014,
0.1163065,
0.3381898,
0.4062877,
0.071264... |
Coprecipitation of active uridine kinase and phosphomonoesterase from rat kidney by Zn2+-ions. III. Enzymes relevant to cancer chemotherapy. | Partially purified enzyme fraction from rat kidney possessing high uridine kinase and phosphomonoesterase activity was insolubilized by means of zinc precipitation without substantial loss of the activity. While uridine kinase in a soluble and Zn-precipitated form was inhibited by low concentrations (0.5-1.0 mM) of Zn2... | 14,785 | [
-0.2024699,
0.0456515,
-0.1464626,
-0.1118942,
0.02505157,
-0.35497,
-0.203048,
0.4700691,
0.1461703,
0.1828176,
0.5266983,
0.03438734,
-0.2198493,
-0.1469468,
-0.7110465,
0.2741067,
-0.07993124,
-0.1251032,
-0.2098985,
0.2826158,
0.484513,
0.09123028,
-0.1625579,
0.242... |
Baroreflex sensitivity in patients with Takayasu's aortitis. | Takayasu's aortitis is an arterial inflammatory disease of arteries of unknown etiology. Fainting is a common symptom and has been attributed to ypersensitivity of the baroreflex. We studied baroreflex sensitivity in 11 patients with Takayasu's aortitis and compared it with that of eight control subjects of comparable ... | 14,792 | [
0.2628234,
-0.3739973,
-0.4291463,
0.1153965,
-0.005924224,
-0.4253275,
-0.04136331,
0.3411416,
0.05997443,
-0.1112525,
0.2405823,
-0.06411965,
0.06953917,
0.06569452,
-0.3851156,
-0.3184091,
-0.4542676,
0.2334363,
-0.03796485,
0.05191637,
0.3256854,
-0.1622766,
-0.049864... |
Three types of paranoid processes. | In classical descriptive psychiatry the term 'paranoid' is often used ambiguously -- referring to a variety of clinical processes which should be more clearly differentiated. Specifically, in this paper, we have differentiated three distinct sets of clinical phenomena all usually lumped together as 'paranoid': 1. Paran... | 14,813 | [
-0.1855022,
0.01852468,
-0.08246313,
-0.4526091,
0.1549477,
-0.2751365,
-0.3119357,
-0.3095945,
0.04422968,
0.1180239,
-0.04033306,
0.07304493,
-0.09566686,
-0.04530074,
-0.02336674,
-0.00156186,
-0.2713102,
-0.164971,
0.1071513,
-0.01001237,
0.09453984,
0.4214,
-0.064904... |
Characterization of the pH 4.0 endonuclease from adenovirus-type-2-infected KB cells. | The properties of the pH 4.0 endonuclease from adenovirus-type-2-infected KB cells were determined. The enzyme has a molecular weight of approximately 40000. Its pH optimum is at pH 4.0, it is not inhibited by ethylenediaminetetraacetate (EDTA), and it is active at temperatures up to 60 degree C. The enzyme cleaves ade... | 14,826 | [
-0.2058421,
-0.1260522,
-0.261335,
-0.07908396,
0.04945394,
-0.2102627,
-0.1474865,
-0.002493501,
0.1624873,
-0.07184305,
0.1783241,
0.06878947,
0.169864,
-0.1850686,
-0.4985123,
-0.02370412,
-0.2961456,
0.2590574,
0.2369208,
0.3052864,
0.4766125,
0.1080666,
-0.1159697,
... |
New developments in our knowledge of the chemistry of renin. | Although the role of renin in hypertension continues to be incompletely defined, recent progress in the chemistry of renin has been considerable. Extensive purifications of hog kidney renin and the renin-like mouse submaxillary gland enzyme have been achieved. Various inhibitory peptides based on tetradecapeptide renin... | 14,850 | [
-0.1673374,
-0.2396659,
-0.2685265,
0.1278697,
0.3670662,
-0.3770305,
0.07417783,
0.3484023,
0.5051295,
0.3361059,
0.01074655,
-0.248151,
0.1542541,
-0.3881074,
-0.4006743,
0.1243767,
-0.2647254,
0.06419755,
0.140982,
0.1691674,
-0.04274532,
0.2109849,
-0.3963847,
-0.17... |
Reproduction of the eosinopenia of acute infection by passive transfer of a material obtained from inflammatory exudate. | Studies of the eosinopenic effect of acute inflammation were conducted in mice previously rendered eosinophilic with trichinosis. Exudate removed from a pneumococcal abscess contained material (eosinopenic factor [EF]) capable of causing eosinopenia of 4- to 24-h duration when injected intraperitoneally into eosinophil... | 14,891 | [
-0.1923816,
-0.2640818,
-0.1366857,
0.01414864,
0.06656787,
-0.1095477,
0.3253002,
-0.159191,
-0.1546682,
-0.160913,
-0.227027,
0.1162444,
0.1031982,
0.1396755,
-0.03114735,
-0.06825244,
-0.2681649,
-0.2432643,
-0.1937865,
0.336627,
0.1288536,
-0.001641847,
-0.3922858,
... |
Purification of several proteolytic enzymes by tosyl- and carbobenzoxy-triethylene-tetramine-sepharoses. | Tosyl-triethylenetetramine-Sepharose (Tos-T-Sepharose) and carbenzoxytriethylenetetramine-Sepharose (Z-T-Sepharose) were found to be adsorbents utilizable in the purification of several microbial and animal proteases. The former Sepharose derivative adsorbed alpha-chymotrypsin, trypsin, subtilisin, thermolysin and neut... | 14,898 | [
-0.006995314,
-0.4519755,
0.1086705,
0.1181768,
-0.1201564,
-0.2862943,
-0.08656529,
-0.2284612,
-0.1692877,
0.3646875,
0.03212843,
0.2341312,
0.02604216,
-0.1079876,
-0.3618441,
0.1439407,
-0.4025521,
0.1689163,
0.3081984,
0.2617621,
0.08513869,
0.0260976,
-0.2500004,
... |
Subcellular distribution of pyridoxal kinase in ox retina. | PL kinase activity has been determined in primary and secondary subcellular fractions of ox retina. Enzymic activity is predominantly located in the soluble fraction (S3). About 65% of the recovered PL kinase activity of crude mitochondria is released from synaptosomal fraction after hypoosmotic treatment. PL kinase ac... | 14,904 | [
0.01846468,
-0.1776779,
-0.03751487,
-0.1383142,
-0.1750596,
-0.02187256,
0.3128556,
0.1694392,
0.116412,
-0.01137019,
0.1193083,
0.2117248,
0.04893386,
0.04071203,
-0.306689,
0.1852372,
-0.7242218,
0.1708294,
0.1753755,
0.3807926,
0.3114702,
0.5934396,
-0.129179,
0.137... |
Sterol 24(28) methylene reductase in Saccharomyces cerevisiae. | Optimal conditions for the 24(28)methylene reductase were obtained. The enzyme assay provided for unusually high activity; the Km was determined to be 10.8 mum. The enzyme activity was increased in cells grown with ethanol as the substrate. | 14,922 | [
-0.2703189,
-0.2257168,
-0.1982127,
-0.300289,
-0.06531975,
0.159077,
-0.1154817,
0.01088491,
0.1207434,
-0.2486487,
0.2596618,
0.05142656,
0.04160581,
0.3731801,
-0.4507797,
0.248731,
-0.7437154,
0.2775847,
-0.1303798,
0.4455297,
0.4004872,
0.2817748,
0.1078912,
-0.000... |
Purification and some properties of an extracellular alpha-amylase from Bacteroides amylophilus. | A medium was developed to obtain maximum yields of extracellular amylase from Bacteroides amylophilus 70. Crude enzyme preparation, obtained by ammonium sulfate precipitation of cell-free broth, contained six amylolytic isoenzymes that were detected by isoelectric focusing and polyacrylamide gel electrophoresis. One o... | 14,926 | [
-0.02703213,
0.0006004123,
-0.3916246,
0.2193552,
0.04526027,
0.1575866,
-0.2787971,
0.04340009,
0.06760761,
-0.08547655,
-0.2249181,
-0.2286091,
-0.1007578,
-0.111074,
-0.515076,
0.2749736,
-0.3281804,
0.1658861,
0.1917627,
0.2680339,
0.3992292,
0.1877111,
-0.126241,
0... |
Kallikrein inhibitors in rat plasma. | The kallikrein inhibitor contents of human and animal plasma were determined with glandular kallikreins [EC 3.4.21.8]. One ml of plasma could inactivate 20-700 kallikrein units (KU). Rat plasma was the most potent and inactivated 230-700 KU. However, no enzyme capable of inactivating kallikrein could be found in this p... | 14,935 | [
-0.1817722,
0.1393581,
-0.4274534,
-0.2062787,
-0.178505,
-0.02562977,
0.1284187,
-0.2270236,
0.07901043,
-0.00399978,
0.3467362,
0.03481701,
0.4203932,
0.2202506,
-0.1977213,
0.05158987,
-0.4006916,
-0.02982297,
0.1805374,
-0.0006739128,
0.1525426,
0.08075329,
-0.0442337... |
Kinetics of conformational change of troponin-C induced by proton binding or removal in the absence of calcium ions. | The kinetics of the conformational change of troponin-C induced by binding or removal of protons was studied by a stopped-flow pH-jump spectrofluorometric method. In the pH-down experiment (to investigate the kinetics of conformational change from the deprotonated state to the protonated state), a single first-order re... | 14,938 | [
-0.2092194,
-0.1271719,
-0.4242787,
0.08343612,
-0.01351577,
-0.04445992,
-0.200146,
0.0229753,
0.05983178,
0.1258114,
-0.09194351,
0.1994467,
0.01992389,
-0.08939651,
-0.6009321,
-0.2675045,
0.01250497,
0.1424578,
0.1590494,
0.2861394,
0.4878111,
0.05921406,
-0.0742574,
... |
Tryptic cleavage of rat liver sulfite oxidase. Isolation and characterization of molybdenum and heme domains. | Treatment of rat liver sulfite oxidase with trypsin leads to loss of ability to oxidize sulfite in the presence of cytochrome c as electron acceptor. Ability to oxidize sulfite with ferricyanide as acceptor is undiminished, while sulfite leads to O2 activity is partially retained. Gel filtration of the proteolytic prod... | 14,956 | [
-0.1868968,
0.08560342,
-0.1539809,
0.3696369,
-0.1268885,
-0.1902908,
0.3456573,
-0.345673,
0.09905559,
0.238443,
0.01987038,
-0.1527599,
0.04610466,
0.1732144,
-0.2607571,
0.03792513,
-0.6361135,
0.08897887,
0.2083085,
0.0454286,
-0.01122461,
0.4034915,
0.1374425,
0.2... |
Proton magnetic relaxation of aspartate transcarbamylase - succinate complexes. | Nuclear magnetic relaxation methods were used to investigate the interaction of the inhibitor succinate with aspartate transcarbamylase from Escherichia coli. Over the pH range 7 to 9, the dissociation constant for succinate remains less than the inhibitor concentration used for most of this work (0.05 M). As a result,... | 14,960 | [
0.003925713,
0.1097573,
-0.02120588,
0.04427917,
-0.1836586,
-0.2190686,
-0.2522714,
0.101851,
0.1554655,
0.1811458,
-0.1361245,
0.2638908,
0.09975523,
0.3302707,
-0.5979617,
-0.0001529965,
-0.395676,
-0.1024337,
-0.01768146,
0.4382808,
0.3039696,
0.1896766,
-0.1005519,
... |
Cell lines from old immunodeficient donors give normal responses in young recipients. | Two different immune responses were compared in spleen cells obtained from old and young CBA/HT6J mice. Spleen cells from old mice (23 to 33 months) responded about half as well as did spleen cells from young mice (4 to 10 months) in the adoptive transfer anti-sheep red blood cell (SRBC) plague-forming assay, and cause... | 15,033 | [
0.03827007,
-0.4516692,
0.04361298,
-0.2806539,
0.344983,
-0.1787311,
0.1288413,
0.5077862,
0.03209956,
0.003030955,
-0.1315203,
0.3391752,
0.05269217,
0.1291901,
-0.5462664,
-0.3037995,
-0.04806987,
0.2071326,
0.02753976,
0.6003492,
0.3874214,
0.169177,
-0.1309069,
-0.... |
Mouse lymphocytes with and without surface immunoglobulin: preparative scale separation in polystyrene tissue culture dishes coated with specifically purified anti-immunoglobulin. | Mouse spleen cells could be preparatively separated into immunoglobulin positive (Ig+) and immunoglobulin-netative (Ig-)populations by incubating as many as 2 X 10(8) cells per 100 mm diameter petri plate coated with specifically purified goat anti-mouse immunoglobulin. The non-adherent population was 95% or more Ig-, ... | 15,036 | [
-0.150366,
-0.0631934,
-0.1558902,
-0.09390929,
0.2183162,
-0.01696442,
-0.03396537,
0.3871951,
0.1865765,
0.07128873,
-0.1593894,
0.2481485,
0.1258373,
0.1830573,
-0.3969271,
0.05436594,
-0.292354,
0.1381927,
-0.09649724,
0.3173746,
0.3318847,
-0.06195816,
-0.03478042,
... |
Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats. | Imipramine and clomipramine were administered to rats by the oral and intramuscular routes as single and multiple doses. The concentrations of both drugs and their active demethylated metabolites desipramine and desmethylclomipramine were measured in blood plasma, blood cells and brain. The concentrations of the metabo... | 15,053 | [
-0.5110961,
0.2743654,
-0.1755976,
-0.3696386,
0.3707841,
-0.2146941,
-0.4513807,
0.1245344,
-0.4187223,
-0.06479859,
0.1814363,
0.3344401,
0.096149,
0.1438447,
-0.3878262,
-0.007368959,
-0.5745038,
0.2360374,
0.2633076,
0.2664888,
0.1760913,
0.3267685,
0.06407695,
-0.2... |
Dimensional changes of compacts after compression. | A non-contact optical technique has been used to measure changes in the heights and diameters of compacts prepared from sodium chloride, spray dried lactose, two samples of methylcellulose powder and two spray-dried lactose-maize starch granulations. Both sodium chloride and spray dried lactose exhibited relatively sma... | 15,067 | [
-0.09609963,
0.3520912,
0.4276167,
-0.1467785,
-0.193354,
-0.08030638,
-0.09298922,
-0.2030797,
0.1200291,
-0.04597237,
-0.1130641,
-0.4136898,
-0.3675281,
0.06075116,
-0.3996532,
0.04816954,
0.09340604,
0.2307534,
-0.01670422,
-0.1498029,
0.4358385,
0.01884859,
0.2074758... |
Cathepsin D activity in bovine articular cartilage, synovial membrane and fluid: degradation of cartilage proteoglycans from same joint. | Cathepsin D type proteases were extracted from articular cartilage, synovial membrane, and synovial fluid from normal, adult bovine knee joints. A sensitive enzyme assay made it possible to measure protease activity in the different tissues from individual joints. Highest activity was found in the synovial membrane, wh... | 15,110 | [
0.04256939,
0.1213847,
-0.1667088,
0.4107797,
-0.05911341,
0.09954693,
0.04072036,
0.4527094,
0.02969171,
0.08618668,
0.1019619,
-0.1499661,
-0.0122414,
-0.1295245,
0.2081646,
0.1512304,
-0.4358189,
0.06943739,
-0.05509881,
0.3631209,
0.5805236,
-0.1652632,
-0.001593055,
... |
[Intestinal autoflora of the test subjects in a 6-month biological engineering experiment]. | During a 6-month bioengineering experiment the intestinal microflora of four test subjects was examined. Changes in the composition of different groups of intestinal microflora (bifidobacteria, lactic-acid bacteria, sporogenous anaerobes, proteus, etc) were found. In spite of the unstable pattern of the intestinal micr... | 15,161 | [
-0.08963475,
0.01580176,
-0.0832409,
0.5231834,
0.1794141,
-0.1539471,
-0.4886808,
0.1527486,
0.09406301,
-0.5567595,
0.1831289,
-0.0776343,
-0.01375754,
0.1675106,
-0.6146882,
0.2624003,
-0.4754108,
-0.02364935,
-0.3773696,
0.0459605,
0.1700317,
0.6249354,
-0.1762466,
... |
Involvement of cytochrome b5 in the oxidative desaturation of linoleic acid to gamma-linolenic acid in rat liver microsomes. | The effects of antibodies against microsomal electron-transport components on the in vitro activity of delta6-desaturation of linoleic acid to gamma-linolenic acid have been studied in intact microsomal membranes of rat liver. Reduced nicotinamide adenine dinucleotide (NADH) or reduced nicotinamide adenine dinucleotide... | 15,177 | [
-0.02519589,
-0.08224902,
-0.2329509,
0.1560692,
0.06685297,
-0.03676089,
-0.1317027,
0.03126952,
-0.1986983,
-0.08737287,
0.2353131,
0.1088007,
0.4083869,
-0.02596599,
-0.3496448,
-0.1296776,
-0.564801,
0.09204346,
0.1138462,
0.08937956,
0.2137317,
0.2486282,
-0.05182469... |
Physicochemical properties of Sendai virus RNA. II. Effect of ionic strength on thermostability of RNA. | The dependence of the melting point (Tm) and width of the melting range (deltaTm) on the ionic strength and pH of the medium was investigated for the double-stranded RNA formed through self-hybridization during the isolation of RNA from Sendai virus. It was shown that Tm is a linear function of the logarithm of the sod... | 15,210 | [
-0.3441493,
-0.1110002,
-0.1168853,
-0.1253484,
0.1016859,
-0.3962266,
-0.4010282,
0.05829161,
-0.02912847,
-0.1770288,
-0.1293633,
0.1565677,
0.411037,
-0.1626446,
-0.6612294,
-0.2679035,
0.05702628,
0.08105647,
-0.03847187,
0.2852346,
0.524208,
-0.2890113,
-0.1361537,
... |
Affinity labeling of gamma-glutamyl transpeptidase and location of the gamma-glutamyl binding site on the light subunit. | Gamma-Glutamyl transpeptidase, which consists of two nonidentical subunits, is rapidly inactivated with respect to its transpeptidase and hydrolase activities by the gamma-glutamyl analogs 6-diazo-5-oxo-L-norleucine and L-azaserine. Inactivation, which is prevented by gamma-glutamyl substrates (but not by acceptor subs... | 15,260 | [
0.03343728,
0.1817188,
-0.2898428,
0.08471333,
0.0733045,
-0.1131384,
-0.09922337,
0.06092681,
0.06503459,
-0.09035521,
0.1300617,
0.01533565,
0.1046332,
0.3186282,
-0.4573305,
0.3471908,
-0.7169095,
0.2091916,
-0.04128833,
0.1714226,
0.03319868,
0.1819381,
-0.1107544,
... |
[Electrolyte-water balance and acid-base equilibrium in brain tumor patients]. | Electrolyte variations, water-balance disturbances, and acid-base equilibrium disorders observed in patients with brain tumors are due, in the majority of cases, to increases in intracranial pressure and, in a relatively small number of cases, to the particular location of the tumor. Severe pathological pictures are no... | 15,294 | [
-0.467867,
-0.03842578,
-0.0831152,
-0.3497234,
0.2634795,
-0.3809667,
-0.2073353,
-0.2344339,
-0.06002259,
0.1304487,
0.04540541,
0.2010474,
-0.1694031,
-0.1813446,
-0.2189013,
-0.2418983,
-0.1716138,
0.2955106,
0.1995503,
0.05914338,
0.1180638,
0.1558277,
-0.0417354,
... |
The influence of hypoxia and acidity on the hyperthermic response of malignant cells in vitro. | Colony formation of JB-1-E tumor cells was studied after hyperthermic treatment (42.5 degrees C) at a pH of 6.4 or 7.2 under hypoxic and euoxic conditions. At a pH of 7.2 and normal oxygen tension, there was a moderate decrease in colony formation with increasing duration of hyperthermic treatment (To = 65 min.). This ... | 15,300 | [
0.009833324,
-0.4024931,
-0.06328475,
-0.1442876,
-0.08299309,
0.02530477,
0.05214609,
-0.2730984,
-0.1035649,
-0.2199506,
-0.2714199,
0.1144855,
-0.1391167,
-0.1302558,
-0.1777972,
-0.225589,
-0.1774845,
0.2866785,
0.0666812,
0.1958653,
0.5422053,
0.266021,
-0.007859305,... |
Postnatal changes in blood respiratory characteristics in an American opossum (Didelphis virginiana). | The oxygen affinity of opossum blood changes in the postnatal period. The youngest opossums studied were 53 days of age (dated from the day of transit from vagina to pouch) and still confined to the maternal pouch: they had a blood P50 of 32.6 +/- 2.9 mm Hg. The blood P50 value then increased significantly, in two step... | 15,307 | [
0.05975481,
-0.2708528,
-0.3997491,
-0.4800103,
-0.09447867,
-0.09361059,
-0.3260961,
-0.2620729,
-0.01926375,
-0.2673358,
0.06885624,
0.008429315,
-0.2184486,
-0.3619263,
-0.8679088,
-0.2326088,
-0.4935493,
0.04432504,
0.4968216,
0.1170137,
0.2500778,
0.4031247,
-0.00562... |
Tris buffer attenuates acetylcholine responses in Aplysia neurons. | The commonly used buffering agent tris(hydroxymethyl)methylamine (tris) antagonizes the action of iontophoretically applied acetylcholine on neurons of Aplysia californica. Concentrations of 5 to 10 millimolar tris markedly reduced both excitatory and inhibitory responses. | 15,317 | [
0.02226259,
-0.2382834,
-0.3019095,
-0.1585262,
-0.1637539,
0.04882321,
-0.07843111,
-0.1632152,
0.03027024,
-0.1454717,
0.1562097,
0.4165533,
0.09336228,
0.1302162,
-0.4145603,
-0.04630207,
-0.5915697,
0.1730472,
-0.1528016,
0.09921175,
0.1665799,
0.04700752,
0.1702858,
... |
Medical treatment of hypertension. | The management of hypertension with current hypotensive drugs on the South African pharmaceutical market is reviewed. The advent of the use of beta-adrenergic blocking agents and vasodilators in the treatment of hypertension is promising. | 15,323 | [
-0.2633269,
0.2212893,
-0.2552215,
-0.07373444,
0.02745845,
-0.1886395,
-0.3360144,
-0.0183112,
0.1022401,
-0.2459174,
0.0267621,
0.1559008,
0.1793081,
0.0637014,
-0.4499021,
-0.1383792,
-0.1883164,
0.05147105,
0.0123255,
0.02564191,
-0.131038,
0.2412583,
-0.2762815,
-0... |
Local mechanism of CO2 action of cat pial arterioles. | The effect of local hypercapnic acidosis or local hypocapnic alkalosis on pial arterioles were studied in anesthetized cats equipped with a cranial window for the direct observation of the pial microcirculation of the parietal cortex. Changes in PCO2 and pH of the extracellular fluid were induced by perfusing the space... | 15,334 | [
-0.1374239,
-0.08533441,
-0.1184695,
0.04546472,
0.08830304,
0.1147534,
-0.0202685,
-0.1803845,
-0.0186706,
0.1736817,
-0.005680694,
-0.1274328,
-0.02324838,
-0.2538189,
-0.1735813,
-0.08075477,
-0.6704395,
0.08043943,
0.03817349,
0.1052619,
-0.2276532,
0.1110665,
0.13115... |
Changes in agglomeration of human red blood cells in liquid storage in CPD media. | A procedure which may distinguish between old and new CPD blood units in liquid state is described. It is based on the observation of increased tendency to reversible agglomeration in old erythrocytes in liquid preservation. Erythrocytes clump together when they are mixed with low ionic strength solutions in pH range o... | 15,336 | [
-0.1208199,
0.1924814,
0.03269049,
0.09695233,
0.2498754,
-0.5509182,
-0.2866041,
0.1316289,
0.05543542,
0.04467247,
0.1543949,
0.2374933,
-0.04622291,
0.1358587,
-0.2193436,
-0.2391002,
-0.1291778,
-0.1203699,
-0.2543792,
0.2514339,
0.5301296,
0.1433005,
-0.09449811,
-... |
[Fetal heart rate, dip area and acid base observations in breech and vertex deliveries (author's transl)]. | Fetal heart rate (FHR), dip area (DA) and the acid base status (AB) were investigated in breech deliveries (BD) (N= 167) and in group of spontaneously delivered vertex presentations (VP) (NFHR, DA=50; NAB=109). 90 minutes prior to delivery fetal heart rate and dip area were in both groups not significantly different. H... | 15,354 | [
-0.03902514,
-0.2257795,
-0.2180247,
0.1839647,
0.3459438,
-0.2582143,
-0.1073127,
0.02422756,
-0.2669214,
0.2201641,
0.2201777,
-0.02052958,
-0.02342073,
-0.3501886,
-0.3029198,
-0.6152322,
-0.4329449,
0.3805021,
0.1403729,
-0.2306139,
0.7881423,
0.01802878,
-0.08538934,... |
[Hemodynamic effects of Etomidate]. | Hemodynamic variations due to Etomidate administration were studies in 10 patients submitted to artificial ventilation. Etomidate was given at a 0.37 mg/kg B.W. dosage. Cardiac rate, mean arterial B.P., C.V.P., mean arteial pulmonary pressure, mean pulmonary capillary pressure and cardiac output were investigated. From... | 15,477 | [
-0.3144302,
0.0153798,
-0.2436678,
-0.1883247,
-0.1046115,
-0.1414335,
-0.4247218,
-0.1243525,
-0.2421831,
-0.09799626,
0.1213047,
0.2624894,
0.03284783,
-0.2010078,
-0.4322705,
-0.3457074,
-0.7175439,
0.1737877,
0.01487875,
0.4367988,
-0.1073773,
-0.07165147,
-0.02469821... |
[Continuous measurement of arterial pressure by means of an arterial catheter. Its value in secondary transport]. | It is of no much use to try to assess the cardiovascular condition of patients with impending or confirmed shock by taking the blood pressure with the classical arm cuff, especially if arterfacts such as noise, vibrations, shaking etc... are interfering. Instant continuous measurement of blood pressure by means of arte... | 15,482 | [
-0.1282903,
0.147347,
-0.1788428,
0.01503559,
0.01509252,
-0.257407,
-0.2420091,
-0.0007093317,
0.1665238,
-0.172366,
0.05455915,
-0.1721554,
0.3829592,
-0.211434,
-0.2573839,
-0.03275847,
-0.3214004,
-0.3112005,
-0.1712452,
0.3383832,
0.4100218,
-0.3589179,
-0.1897168,
... |
[Macrokinetic equations of pH effect on the growth of Actinomyces aureofaciens and biosynthesis of tetracycline]. | The effect of pH on the culture respiration rate at different concentrations of glucose in the medium was studied. It was found that the hydrogen ions showed their effect irrespective of the subsrate concentration in the medium. In this connection a type of macrokinetic equations of the effect of pH on the growth and a... | 15,502 | [
0.01031811,
-0.5269636,
-0.1555189,
0.3737797,
-0.1933188,
0.1569562,
-0.2075886,
-0.02558968,
0.05928755,
-0.07902177,
0.0114606,
-0.1156721,
-0.1604641,
0.4883713,
-0.1030698,
-0.1303413,
-0.3953223,
0.2753026,
-0.04324077,
-0.1151208,
0.7482095,
-0.2214364,
0.1389966,
... |
Effect of culture conditions on synthesis of L-asparaginase by Escherichia coli A-1. | The nutritional requirements and culture conditions affecting biosynthesis of L-asparaginase in a mutant of Escherichia coli HAP designated strain A-1 were studied. Asparaginase activity was increased by the addition of L-glutamic acid, L-glutamine, or commercial-grade monosodium glutamate. The rate of enzyme synthesi... | 15,509 | [
-0.1805325,
-0.05055925,
-0.175582,
0.3164078,
-0.2565196,
0.04330475,
-0.08968338,
-0.08242278,
-0.0139249,
0.1848596,
0.1202599,
0.1163306,
-0.4000925,
0.4414475,
-0.1556166,
0.327886,
-0.4443156,
0.05580694,
-0.05693816,
-0.01974064,
0.3013178,
0.1306516,
0.01889677,
... |
Acidostability of speroplasts prepared from Thiobacillus thiooxidans. | Thiobacillus thiooxidans was acidostable even in the absence of its respiratory substrate, elementary sulfur. This suggests that the acidostability of the bacterium was enery-independent. The organism was subjected to osmotic shock with 0.75 M sucrose at 0 degrees C and then treated with snail intestinal juice in the p... | 15,528 | [
0.1541568,
-0.3479278,
-0.006356497,
0.1284665,
-0.1461477,
-0.3120093,
-0.05858307,
-0.1304218,
0.1689074,
-0.2862935,
0.1041981,
-0.02512634,
-0.2051747,
-0.3145722,
-0.1978129,
0.1802887,
-0.3531438,
-0.1660143,
0.2994217,
0.1533261,
0.2906384,
-0.03991451,
-0.159218,
... |
Penicillinase (beta-lactamase) formation by blue-green algae. | Beta-Lactamase (penicillinase) activity was found in a number of strains of blue-green algea. In some cases, this enzyme permitted algae to overcome the inhibitory effects of penicillin. Production and localization of beta-lactamase were studied in a unicellular species, Coccochloris elabens (strain 7003), and in a fil... | 15,530 | [
-0.1706025,
0.162526,
-0.2421737,
0.2916798,
-0.4579195,
0.02593219,
-0.4170173,
-0.2831788,
0.3848045,
0.1039319,
-0.04088963,
-0.3802065,
-0.4447985,
-0.008991694,
-0.3938755,
-0.1001664,
-0.2754731,
0.4478676,
0.02001218,
0.08904506,
0.2462992,
0.6386787,
-0.05610452,
... |
Fluorine-19 nuclear magnetic resonance studies of effects of ligands on trifluoroacetonylated supernatant aspartate transaminase. | The selective reaction of Cys-45 and -82, on the one hand, and Cys-390, on the other, with 3-bromo-1,1,1-trifluoropropanone allows for the probing of these regions of aspartate transaminase in the absence and in the presence of enzymatic ligands by 19F nuclear magnetic resonance (NMR). The 19F chemical shifts of the re... | 15,584 | [
-0.1480333,
-0.1401722,
-0.154718,
0.04110097,
-0.07135795,
-0.1684543,
0.1088231,
0.1356771,
-0.01196913,
0.02827523,
0.03152606,
0.01446784,
0.2651449,
0.1373771,
-0.6895187,
0.0003130051,
-0.3097867,
0.2227566,
-0.02732477,
0.645865,
-0.1186254,
0.3809561,
-0.01295278,... |
Phosphate transport in Micrococcus lysodeikticus. | Phosphate accumulates in Micrococcus lysodeikticus cells against a concentration gradient, by an energy-dependent process. The phosphate transport is derepressed during phosphate deprivation. The depression process is inhibited by chloramphenicol. The apparent Km of phosphate transport is 4.3 micronM. The activation e... | 15,596 | [
-0.3436918,
-0.2371917,
0.04130122,
-0.1296067,
-0.3051925,
0.2057231,
-0.2112019,
0.1605192,
-0.158718,
-0.1432815,
0.2889556,
0.3459646,
-0.1014242,
0.3230104,
-0.62445,
0.2812451,
-0.3938838,
-0.08741806,
-0.1719854,
0.1314142,
-0.01190395,
0.05772514,
0.0198819,
0.2... |
Physicochemical properties of alpha- and beta-fibrinogenases of Trimeresurus mucrosquamatus venom. | alpha- and beta-Fibrinogenases (EC 3.4.21.5) were purified from Trimeresurus mucrosquamatus venom by the technique of recycling chromatography. Both enzymes were single polypeptide chains and homogeneous as judged by sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis and ultracentrifugation. The sedimentat... | 15,616 | [
-0.09966316,
-0.02583697,
-0.1241004,
0.05086279,
-0.02766579,
-0.2266069,
0.01437141,
0.1360889,
-0.03272472,
0.1616151,
0.08160552,
0.1483929,
-0.03008785,
0.02938866,
0.04590467,
0.1281858,
-0.3228909,
0.1791903,
0.1846509,
0.5904298,
0.1861315,
0.1161358,
-0.2834767,
... |
Activation of liver guanylate cyclase by bile salts and contaminants in crude secretin and pancreozymin preparations. | Crude preparations of secretin or pancreozymin increased and at higher concentrations decreased guanylate cyclase (GTP pyophosphate-lyase, EC 4.6.1.2) activity from soluble and particulate fractions of rat liver homogenates. Partially purified and synthetic secretin were without effect as was the biologically active oc... | 15,619 | [
0.07726237,
-0.09819275,
-0.2477566,
0.1669017,
-0.3019693,
-0.2343584,
-0.09267189,
-0.1373551,
0.01724402,
0.2636054,
-0.01665827,
-0.09567329,
0.01062058,
0.03770244,
-0.06181342,
0.08852519,
-0.333451,
0.1297034,
0.1647446,
0.2716026,
0.1468724,
0.2206166,
-0.1364014,... |
Structural studies by proton magnetic relaxation of stereochemical probes. II. Allosteric effects in human methaemoglobin. | The haem-iron accessibility to solvent molecules in human aquomet- and fluoromethaemoglobin was studied by the magnetic relaxation of protons from a stereochemical probe (methanol in deuterated solutions) in its dependence on allosteric effects induced by inositol hexaphosphate and pH between 5.5 and 8.5. The exchange ... | 15,624 | [
-0.4134677,
-0.205526,
-0.4165828,
0.03148409,
0.08730255,
0.07794779,
-0.02544589,
0.02818025,
-0.07720646,
-0.05706571,
-0.03152463,
0.3642015,
-0.1811455,
-0.01038046,
-0.6273385,
-0.08272877,
-0.3362406,
0.1707039,
-0.2809903,
0.07014114,
0.4363314,
0.2049792,
-0.1378... |
[Glutamine metabolism regulation in Chlorella pyrenoidosa. Regulation of Chlorella glutamine synthetase activity by amino acids]. | Effect of glutamine and its metabolites (amino acids) on Chlorella glutamine synthetase (GS) (E.C.6.3.1.2) in the presence of Mg or Mn was studied. Purified GS preparation was used, isolated from Chlorella grown in the presence of NH as a sole nitrogen source. Glutamate, aspartate, alanine and glycine inhibit GS activi... | 15,647 | [
-0.1125978,
-0.1249131,
0.01392957,
-0.2678854,
-0.1038933,
0.1325594,
-0.1750984,
-0.04816921,
-0.1750401,
0.02714435,
-0.1153092,
0.1410178,
-0.3521695,
0.07851875,
-0.6636475,
0.04567007,
-0.5054645,
0.3683632,
-0.06076818,
0.5325728,
0.2854598,
0.1501586,
-0.159923,
... |
[Adenine uptake in Neurospora crassa mycelium]. | The uptake of 8-C14-adenine in N. crassa strain Lindegren (+) was studied. The ability of N. crassa cells to uptake adenine from the medium reaches maximum at the very beginning of the logarithmic stage of growth. Adenine enters the mycelium against the concentration gradient. The uptake of adenine is maximal at 25-30 ... | 15,650 | [
-0.2420463,
-0.08998238,
-0.2139882,
-0.3230117,
0.294073,
0.06062237,
-0.2589953,
-0.1189579,
0.03813083,
-0.198034,
0.06396515,
-0.1013887,
0.1423373,
0.2209475,
-0.8312768,
0.01375252,
-0.7944198,
0.2705839,
-0.03875566,
0.005046085,
0.6193352,
0.1998372,
-0.1385993,
... |
[Purification, properties and quaternary structure of glutamine synthetase from Chlorella]. | A highly purified preparation of glutamine synthetase from chlorella grown on a medium containing nitrate as a sole source of nitrogen, was isolated and characterized by disc-electrophoresis and analytical ultracentrifugation. The N-terminal amino acid of glutamine synthetase is glycine. The molecular weight of glutami... | 15,657 | [
-0.08681586,
0.1953965,
0.2355681,
0.1043282,
-0.2919027,
-0.2093802,
-0.1680917,
-0.0455099,
-0.05777287,
0.01130794,
0.02668803,
0.08512307,
-0.220118,
0.2079454,
-0.1910445,
-0.09950032,
-0.4233822,
0.1847579,
0.2405586,
0.286282,
0.3827642,
0.1578387,
-0.1198685,
0.... |
[Some physicochemical properties of modified trypsin]. | Physico-chemical properties of trypsin covalently bound with human serum albumin by glutaric aldehyde have been studied. The modification of the enzyme practically caused no changes in the pH optimum of trypsin. The inhibition of modified trypsin by inhibitors from soy beans and human blood serum has been also studied.... | 15,658 | [
0.05378164,
-0.09400592,
-0.04611688,
0.1743618,
0.02605078,
-0.04838156,
-0.0340497,
0.2258166,
0.1277306,
0.05699371,
0.06641469,
0.3442658,
-0.02030776,
-0.2316379,
-0.5822287,
0.107821,
-0.7145923,
0.105622,
-0.0996692,
0.2663436,
0.01665897,
0.3073256,
-0.4782162,
... |
[Effect of abrogating hybrid resistance on the survival of radiation chimeras]. | A study was made of the effect of the hybrid resistance abrogation by means of the lymphoid cell administration on the survival of the lethally irradiated mice protected by the transplantation of the semiallogeneic bone marrow. Injection to the C57BLxCBA recipients of the C57BL lymphoid cells one day before the irradia... | 15,680 | [
0.0601745,
-0.2222672,
-0.1599416,
-0.06069838,
0.03624611,
-0.4658045,
-0.2275323,
-0.1885624,
0.1515439,
0.04820438,
-0.02673203,
0.05061185,
-0.004130282,
0.156456,
-0.7821442,
-0.5933113,
-0.2512082,
-0.0775708,
-0.3349284,
0.3468264,
0.2849632,
0.09281362,
0.03514976... |
[Immunocompetent lymphoi- cells from pregnant mice studied in the graft-versus-host reaction]. | The capacity of lymphoid cells taken from C57BL/6 mice gravid from the CBA males (the second trimester) to induce the graft-versus-host reaction in the hybrids (CBA X C57B/6) F1 was reduced as compared with the cells of the virgin donors and syngeneic gravid mice. This was expressed by the prolonged survival of the exp... | 15,684 | [
-0.06619343,
-0.279053,
-0.07516664,
-0.01848818,
0.3550494,
-0.3099792,
-0.07984295,
-0.2413252,
-0.01592739,
-0.1724914,
-0.07770555,
0.151197,
-0.09458353,
0.244661,
-0.7052855,
-0.4057868,
-0.3239464,
-0.00251,
-0.1276253,
0.4192937,
0.3723434,
0.3748756,
-0.05725082,... |
[Quantitative changes in gastric juice proteases in dogs during ulcer formation in the stomach]. | Disc-electrophoretic investigation of proteases of the gastric juice of dogs under normal conditions and in experimental atophan ulcer of the stomach demonstrated that in fasting dogs ulceration was accompanied by marked quantitative changes in the protease spectrum. Fraction No. 6 showed a significant elevation agains... | 15,686 | [
-0.268218,
0.180466,
-0.1487694,
0.0008318535,
0.3147951,
-0.2318783,
0.2568994,
-0.09741352,
0.3131127,
-0.2339398,
0.05171664,
-0.00002511078,
0.1021824,
-0.3289935,
-0.3960397,
-0.02873407,
-0.3922634,
0.2978457,
0.3115871,
-0.06901917,
0.08433372,
0.1309268,
-0.001334... |
Thrombin-induced vasodilation in the hindlimb (dog). | The objective of this study is to test the hypothesis that the vasodilation produced by intra-arterial injection of thrombin to the hindlimb of a dog may be caused by the secondary release or production of some vasodilating substance. The vasodilator response to thrombin was compared with the vasodilator response to ac... | 15,689 | [
0.2228847,
0.1763014,
-0.2094929,
-0.2781904,
0.1348984,
-0.2562425,
-0.1777438,
0.04760665,
-0.1488546,
0.173107,
-0.007039191,
0.4160176,
0.09064974,
-0.4225692,
-0.08125653,
0.3471037,
-0.2561339,
0.1377777,
0.03883702,
0.1561857,
0.1561858,
0.2425317,
0.08473683,
-0... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.