title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Ureteral metastasis from Wilms tumor. | Urothelial spread of Wilms tumor is uncommon and only 5 instances of ureteral metastases have been reported previously. A case of Wilms tumor with mid ureteral metastasis is presented and the literature is reviewed. Clinical implications and suggestions for surgical management are discussed. | 177,791 | [
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Isolation of low-virulent mouse hepatitis virus from nude mice with wasting syndrome and hepatitis. | Mouse hepatitis viruses were isolated on DBT cell culture from affected livers in most nude mice having wasting syndrome and chronic hepatitis. These nude isolates were pathogenic for cortisone-treated ICR weanling mice but not for non-treated ones. | 177,794 | [
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Erythropoietin levels in Wistar-Furth Wilms' tumor rats. | Erythropoietin (ESF) levels were assayed in rats bearing the Wistar-Furth Wilms' transplantable tumor. Sites of tumor inoculation varied from subcutaneous, intramuscular, intrarenal (subcapsular), to intraperitoneal. Two-thirds of the animals exhibited ESF elevations without polycythemia, or severe anemia (HCT less tha... | 177,822 | [
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Adenosine 3',5'-monophosphate and the regulation of rat hepatic sterol synthesis: a reexamination based on Sutherland criteria. | Many investigators have reported that adenosine 3',5'-monophosphate (cyclic AMP) at supraphysiologic concentrations (10(-4) M) suppresses lipogenesis in rat livers in vitro. The data in this report demonstrate that the phosphodiesterase inhibitor theophylline does not suppress sterol synthesis by itself nor does it pot... | 177,839 | [
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Genetic and enzymatic analysis of a glycerol kinase deficient mutant in Neurospora crassa. | Genetic analysis showed that the glycerol non-utilizing isolate gly-u(234) of Neurospora crassa is derived by mutation in a nuclear gene situated in the right arm of linkage group I, about 2.2 cross-over units distal to ad-9 and 11 units proximal to nit-1. Enzymatic testings using a radiochemical method indicate that t... | 177,854 | [
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Estrogens and endometrial cancer in a retirement community. | All cases of endometrial cancer occurring among the residents of an affluent retirement community were compared with controls chosen from a roster of all women in the same community. Evidence of estrogen and other drug use and of selected medical conditions was obtained from three sources: medical records of the princi... | 177,870 | [
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[Transmission of impulse trains by nerve fibers upon near-threshold stimulation]. | Impulse trains evoked by stimulation of the hindlimb nerves were studied in group A fibres at the lumbar level of spinal cord in anesthetized cats. Random (Poissonian) trains fo stimuli and trains with modified structure were used. With suprathreshold stimulation the impulse trains in the nerve fibres differed from the... | 177,895 | [
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[Stereological analysis of the degranulation and the contraction of platelets. Application to the ultrastructural study of thrombin induced excretion in vitro]. | A stereological model, which provides quantitative information on the morphology of the platelet release reaction as isolated from platelet aggregation, was developed for the human platelets separated from blood by Mustard's procedure. Three morphologically defined spaces (granules, surface-connected canalicular system... | 177,928 | [
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Viral infections that affect the fetus. | Several viral infections besides rubella are known to cause fetal anomalies and disease. Cytomegalovirus, for example, may adversely affect the fetus in a number of ways. Either herpesvirus or hepatitis B virus is transmissible from mother to offspring. Viruses whose potential for fetal harm is less clear are those of ... | 177,962 | [
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Hyperhidrosis and hypohidrosis. | Sweating has an important physiological function concerned with both temperature and fluid balance. Hypohidrosis is uncommon and rarely recognized by the patient. It usually represents damage to the central nervous system or peripheral nerves. Hyperhidrosis may be a feature of general medical diseases such as thyrotoxi... | 177,967 | [
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Distribution of envelope-specific and sarcoma-specific nucleotide sequences from different parents in the RNAs of avian tumor virus recombinants. | The distribution of leukosis-virus- and sarcoma-virus-specific oligonucleotide sequences was investigated in the RNAs of viral recombinants selected for an envelope gene (env) from a leukosis parent and a sarcoma gene (src) from a sarcoma parent. For this purpose 20 to 30 RNase-T1-resistant oligonucleotides were chemic... | 177,972 | [
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Detection of antibody to Varicella-Zoster virus by immune adherence hemagglutination. | A serologic test for measurement of antibody to V-Z virus by immune adherence hemagglutination is described. Initial evaluation of the test has shown it to be highly sensitive, specific, rapid, and simple to perform. The V-Z antigen may be stored at -70 degrees, and the test could be performed in any routine serology l... | 177,988 | [
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Cyclic AMP and central noradrenaline receptors: failure to activate diencephalic adrenergic feeding pathways. | Intracranial injection of graded doses of dibutyryl 3',5'-cyclic adenosine monophosphoric acid (cAMP) at sites in the accumbens/stria terminalis nuclei of satiated rats elicited behavioural arousal and occasional convulsive episodes at higher doses, but failed to affect food consumption even in sites where injection of... | 177,997 | [
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[Technical notes and clinical use of radioimmunologic determination of plasma ACTH]. | Particular aspects of plasma ACTH radioimmunoassay are examinated. The results obtained with this method in adrenocortical diseases (Addison's disease, Cushing's syndrome, congenital adrenal hyperplasia) are reported and clinical value in etiological diagnosis of Cushing's syndrome is outlined. Moreover the results obt... | 178,022 | [
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Studies of growth hormone secretion VIII. Effects of alpha,beta-methylene-ATP on prostglandin induced GH release and cyclic AMP accumlation in rat anterior pituitary glands. | Alpha, beta-methylene-ATP, a competitive inhibitor of adenylate cyclase of liver and fat cell membrane preparations, caused a dose related inhibition of PGE1 and PGE2-induced cyclic AMP accumulation in rat anterior pituitary explants. At the same time, this ATP analog potentiated PGE1 and PGE2-promoted growth hormone s... | 178,028 | [
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Genetic determination of aggressive behavior and brain cyclic AMP. | Inbred mouse strains exhibit differences in brain cyclic AMP concentrations. In two mouse strains, we have shown that both the tendency for aggressive attack and high brain cyclic AMP content are inherited as recessive traits and that these traits maintain a close association in segregating generations. | 178,032 | [
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A reovirus-like agent (rotavirus) in gastroenteritis of children. Virus detection and serological studies. | A reovirus-like agent (rotavirus) was detected in 26 children (44%) when fecal specimens from 59 children with acute gastroenteritis were examined by electron microscopy. No rotavirus was detected in the feces of 49 children with other diseases. Sera from the acute and the convalescent phase from 40 children with acute... | 178,049 | [
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Specific progesterone receptors in dimethylbenzanthracene (DMBA)-induced mammary tumors. | Properties of a progesterone receptor present in the cytosol (105,000 xg supernatant) of dimethylbenzanthracene (DMBA)-induced mammary tumors were studied using the highly potent progestin [3H]R 5020 (17, 21-dimethyl-19-nor-pregna-4, 9-diene-3,20-dione). As shown by sucrose gradient analysis, specific binding of [3H] R... | 178,076 | [
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In vitro sensitivity of Entamoeba histolytica to furazolidone and iodochlorhydroxyquin, separate and combined. | Entamoeba histolytica trophozoites isolated in Robinson's medium from faeces containing cysts, transported from India, have been tested in vitro against the drugs furazolidone, iodochlorhydroxyquin, and both drugs combined as Dependal. Results show the levels at which drug action is significant and that interaction bet... | 178,080 | [
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[Cycloalkylsulfamic acids and their salts. i.v. (author's transl)]. | The sodium salts of cis- and trans-2-methyl-cyclohexylsulfamic acid were synthesized and tasted. There is no difference in their degree of sweetness. | 178,120 | [
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Treatment of glioblastoma multiforme. A review. | Experience in irradiating 114 patients with glioblastoma multiforme is reviewed. The split-course therapy utilized in this series, even to high doses (approximately 5 600 rad in 20 fractions over 45 to 50 days), was not associated with an improved survival and does not seem of benefit over conventional fractionation. A... | 178,151 | [
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A comparative morphometric analysis of the effects of thyroxine and ACTH on the zona fasciculata of rat adrenal cortex. | The effects of thyroxine and ACTH on the ultrastructure of cells of the adrenal zona fasciculata were studied by morphometric analysis and compared by two-way analysis of variance. The results indicate that the effects of thyroxine and ACTH are different and independent. The statistically significant differences in eff... | 178,165 | [
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Additive risk factors in atherosclerosis. | The tissues of human subjects assayed for a higher level of vitamin D than the tissues of 6-month-old swine which had been fed a commercial ration containing 14 times more vitamin D3 than the National Research Council recommended requirement for growing swine. Bioassays of commercial livestock feeds indicate much highe... | 178,169 | [
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Ultrastructure and formation of lamellated inclusion bodies in induced lung tumors of the European hamster. | Utlrastructure and formation of lamellated inclusion bodies (LB) in N-dibutyl-nitrosamine-induced lung tumors in European hamsters are described. Two types of LBs are observed: one with cross-barred lamellae and one with concentric lamellae. Both types develop from lysosome-like dense bodies which are formed by the Gol... | 178,184 | [
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The occurrence and frequency of type C virus-like particles in placentas from patients with systemic lupus erythematosus and from normal subjects. | Type C RNA virus-like particles were found by electron microscopy in term placentas from 3 patients with systemic lupus erythematosus (SLE), 1 with probable SLE, and 2 normal patients. The virus-like particles were mainly of a budding or immature type located at or near the cell membrane of syncytiotrophoblasts in chor... | 178,185 | [
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Limitations of Brief Hospital Treatment. | A total of 175 newly admitted inpatients who lived with their families were randomly assigned to three treatment groups: standard inpatient care and brief hospitalization with and without transitional day care. Case reports of 6 of the 9 patients considered "study failures" illustrate that effective postdischarge adapt... | 178,191 | [
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Demonstration and dimensional analysis of the normal pancreas with gray-scale echography. | For consistent identification of the normal pancreas, preliminary longitudinal scanning at, or near, the mid-line and subsequent oblique scanning in the long axis are necessary prerequisites in delineating the anatomic outline of the pancreas. The range of normal measurements for different anatomical regions of the pan... | 178,212 | [
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Localized nodular synovitis of the knee: a report of two cases with abnormal arthrograms. | The arthrographic appearance in two cases of localized PVS of the knee involving the region of the infrapatellar fat pad is reported. Lesions in this area may present with confusing symptomatology, and the true abnormality may be overlooked in a search for meniscal lesion. The arthrographic picture is non-specific and ... | 178,217 | [
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-0.1285678,
-0.341419,
-0.1092875,
0.2231155,
0.3452372,
-0.01766925,
0.1047086,
-0.05757077,
0.03403535... |
Steroid concentrations in cows with corticotropin-induced cystic ovarian follicles and the effect of prostaglandin F2alpha and indomethacin given by intrauterine injection. | In 7 instances, cystic ovarian follicles resulted when adrenocorticotropin (ACTH) was administered daily during the follicular phase of the estrous cycle in cows. Two cows given daily injections of hydrocortisone (cortisol) during the follicular phase of the estrous cycle did not develop cystic ovaries. Plasma concentr... | 178,251 | [
-0.0258392,
0.06862681,
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0.3439948,
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0.04021954,
0.07688183,
0.1127402,
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0.117161,
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0.3826228,
0.02950796,
0.01695802,
0.07505961,
-0.2253178... |
Pathogenesis of duck plague in the bursa of Fabricius, thymus, and spleen. | White Pekin ducks were inoculated orally with duck plague virus and killed at 24-hour intervals after inoculation. Spleen, thymus, and bursa of Fabricius were collected and examined by light, fluorescent, and electron microscopy. Necrosis of lymphocytes occurred in the bursa of Fabricius, thymus, splenic periarteriolar... | 178,252 | [
-0.05699223,
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0.09742116,
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0.5129313,
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0.3708417,
-0.005798839,
0.2489315,
0.3493613,
-0.0332... |
[Inflammatory pseudotumor of the lung in infancy (histiocytoma) (author's transl)]. | A four year old boy with a clinical picture of acute pneumonia is presented. Antibiotic therapeutic improved the clinical and analytic symptomatology but a round, radiologic shadow persisted after three months of evolution. Thoracotomy was performed and by histopathologic examination histiocytoma of lung diagnosed. Lit... | 178,261 | [
0.11552,
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0.1567651,
0.2151087,
0.3180092,
0.09679858,
0.2708069,
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... |
In vivo synergy between 6 beta-amidinopenicillanic acid derivatives and other antibiotics. | Both an oral and a parenteral form of a 6beta-amidinopenicillanic acid derivative were found to have appreciable activity against gram-negative bacteria and poor activity against gram-positive bacteria in vivo. When administered orally or parenterally, definite synergy was demonstrated between the amidinopenicillins an... | 178,275 | [
-0.1226492,
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0.1141148,
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0.07976764,
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0.1475212,
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0.2737642,
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0.2315816,
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-0.09114852,
0.3484264,
-0.2433557,
0.3904296... |
LevoDopa test and estrogen receptor assay in prognosticating responses of patients with advanced cancer of the breast to endocrine therapy. | The ability of L-dopa to arrest pain can be used to predict objective response of skeletal disease to endocrine ablation or additive therapy. In the present study, 43 patients with painful skeletal metastases were evaluated for the relief of pain by L-dopa, given 250 mg to 500 mg orally every 4 hours for 4 days. Sixtee... | 178,277 | [
0.2603329,
0.182392,
0.09779605,
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0.06443086,
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0.1715828,
0.215176,
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0.2... |
[Inhibition of 3', 5'-cyclic AMP phosphodiesterase in the guinea pig lung by a new anti-allergic: 10-(3-quinuclidinylmethyl) phenothiazine (LM 209)]. | The action of a new antiallergic agent, 10-(3-quinuclidinylmethyl) phenothiazine or LM 209, on cAMP phosphodiesterase (PDE) was studied on a guinea-pig lung preparation and compared with that of other compounds such as cromoglycate (I), dexamethasone (II), dexchlorpheniramine (III), promethazine (IV) and theophylline (... | 178,283 | [
-0.2590071,
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0.02287477,
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0.02942413,
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0.04149207,
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0.04311727,
0.05589642,
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-0.6074013,
0.1328644,
-0.1823021,
0.1915207,
0.384118,
-0.0601923,
-0.209746... |
An investigation of the effects of a pyridyl and a piperidyl 1, 3-dioxolane derivative on neuromuscular transmission. | 2-(4'-pyridyl)-1,3-dioxolane methiodide (KCL-301-14) and 2-(1'-methyl-4' piperidyl)-1,3-dioxolane hydroiodide (KCL-301-39) facilitated the force of contraction in low doses and blocked it in higher doses in the in vivo cat soleus muscle preparation. Both drugs in the cat also reversed d-tubocurarine and succinylcholine... | 178,284 | [
-0.01843297,
-0.3112514,
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-0.3591826,
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0.07081322,
0.2425568,
0.1638645,
0.06350376,
0.04085489,
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-0.9693503,
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-0.3389262,
0.1716174,
0.05148855,
0.2710045,
0.1761801... |
Dialysis in renal failure casued by amyloidosis of familial Mediterranean fever. A report of ten cases. | Ten unselected patients with renal failure casued by amyloidosis associated with FMF were treated by regular hemodialysis therapy from 1969 to 1974. They were compared to age-matched control patients treated by hemodialysis in the same unit during the same period, who were suffering from renal failure caused by other d... | 178,285 | [
-0.01762295,
0.04512152,
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0.1244005,
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0.005596426,
-0.1016402,
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0.004404171,
0.3071212,
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-0.04179537,
-0.1019416,
-0.3868333,
0.3177751,
0.234604,
-0.1006439,
0.0096... |
Further observations on subacute sclerosing encephalitis in adult hamsters: the effects of intranasal infections with Langat virus, measles virus and SSPE-measles virus. | Passage by i.c. inoculations of suckling hamsters enhanced the virulence for adult hamsters of Langat virus (TP21), neurotropic strain of measles virus (HNT) and SSPE-measles virus (HBS), not only for i.c. infections but also for intranasal instillations. The various viral strains passaged in hamsters showed a great si... | 178,335 | [
-0.2548445,
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0.2174594,
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0.2805067,
0.4035841,
0.3040354,
0.4444382,
-0.02404131,
... |
Hormonal regulation of pancreatic islet adenyl cyclase. | Adenyl cyclase activity of rat pancreatic islet membrane was increased by secretin, pancreozymin, and isoproterenol, while ACTH, glucagon, growth hormone, and insulin had no effect. Both secretin and isoproterenol activations were enhanced by prostaglandin E1 (PGE1) and GTP. Isoproterenol activation was additive with P... | 178,351 | [
-0.05400317,
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0.03960096,
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0.2203272,
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0.1328882,
0.2274734,
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-0.1471883,
0.2190335,
0.6006077,
-0.2131093,
-0.1970518... |
Phosphorylation of double-stranded DNAs by T4 polynucleotide kinase. | The phosphorylation by T4 polynucleotide kinase of various double-stranded DNAs containing defined 5'-hydroxyl end group structures has been studied. Particular emphasis was placed on finding conditions that allow complete phosphorylation. The DNAs employed were homodeoxyoligonucleotides annealed on the corresponding h... | 178,357 | [
0.192896,
0.05138641,
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0.03547465,
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0.06150188,
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0.09743655,
0.6052875,
0.05802896,
-0.06904384,... |
Gramicidin S-synthetase. A further characterization of phenylalanine racemase, the light enzyme of gramicidin s-synthetase. | 1. Chromatography on hydroxyapatite and on aminohexyl-Sepharose as well as isoelectric focusing were introduced as new effective purification procedures for phenylalanine racemase (EC 5.1.1.11). The enzyme preparations obtained were essentially homogeneous, as demonstrated by specific activity measurements and polyacry... | 178,369 | [
-0.3052776,
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0.08142949,
0.07948991,
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0.2433954,
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0.1821881,
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0.1063594,
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0.1538345,
-0.02457797,
0.4168563,
0.3528483,
0.2379406,
-0.07765754... |
Purification and characterization of phosphodiesterase I from Bothrops atrox. | Phosphodiesterase I from the venom of Bothrops atrox has been purified by successive chromatography on phosphocellulose P-11, hydroxyapatite, and DEAE-cellulose DE 52. The final product gave a single band on sodium dodecylsulfate-polyacrylamide gels and was free of endonuclease, 5' -nucleotidase, and unspecific alkalin... | 178,376 | [
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0.07674389,
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0.1360938,
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0.02052875,
0.2340093,
0.3855638,
-0.02892177,
-0.3005... |
Analysis of estrogen glucuronides. I--Characterization of estrogen glucuronides by gas chromatography mass spectrometry. | The mass spectral characterization of nine kinds of estrogen glucuronides was investigated. The glucuronides were analysed after conversion to n-propyl ester-O-TMS ether derivatives by gas chromatography mass spectrometry. The fragmentation of these derivatives is discussed using deuterium labels and TMS-d9 imidazole. ... | 178,386 | [
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0.1120727,
0.4363772,
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0.3197665,
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0.2197407,
0.3282919,
0.001726954,
-0.0787485,... |
[Lipid oxidation in bilayer lipid membranes linked with the reaction of oxidation of NAD.H by atmospheric oxygen]. | It is shown that along with NAD.H oxidation with air oxygen peroxide oxidation of lipids forming the membrane takes place in bilayer lipid membranes modified with ubiquinone. During nicotin amide oxidation proton absorption takes place. Peroxide oxidation of lipids results in the liberation of H+ ions, which in its tur... | 178,383 | [
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0.1133969,
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0.04630041,
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0.1119231,
0.4288406,
0.218587,
0.04910911,
-0.0... |
[Pyruvate kinase activity in the liver of rats with induced tumors]. | M-isozyme pyruvate kinase activity proved to be elevated in the liver of rats with hepatoma induced by p-dimethylaminoazobenzene. Sodium fluoride surplus in rat diet prevented the increase of this isozyme activity. | 178,389 | [
-0.3203268,
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0.05048335,
0.05489641,
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0.03306761,
0.1815031,
0.1170535,
0.05044192,
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Hydatidiform mole metastasizing to the lung. | Pulmonary lesions developed in three patients with an invasive hydatidiform mole. At open thoracotomy the modules were found to contain molar tissue. Therapy with twice-weekly methotrexate induced complete clinical and biologic remission of the disease in all three patients. | 178,421 | [
-0.09501784,
0.33007,
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0.4501822,
0.3355741,
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0... |
Cell cycle-related hormone carcinogen interaction during chemical carcinogen induction of nodule-like mammary lesions in organ culture. | The immature mammary glands of BALB/c female mice were treated with 7,12-dimethylbenz[a]anthracene (DMBA), 2 micrograms/ml, or 3-methylcholanthrene (10 micrograms/ml) for a 24-hr period at different times during the inital six days of lobuloalveolar growth in hormone-supplemented organ culture. Nodule-like alveolar les... | 178,426 | [
-0.4150265,
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0.05140088,
0.06412101,
0.06328918,
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0.2465441,
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0.08180487,
-0.04698639,
-0.0004877451,
0.1104409,
0.1587853,
0.5468693,
0.09338296,
-0.0222... |
Cyclic nucleotide phosphodiesterase activity in normal and neoplastic rat mammary cells grown in monolayer culture. | The activity of cyclic 3':5'-nucleotide phosphodiesterase (PDE) (EC 3.1.4.17) was measured in cultured normal and neoplastic rat mammary epithelium. Total PDE activity in normal cells was 1.6 to 6 times higher than that in tumor cells over a concentration range of 0.01 to 1 mM cyclic adenosine 3':5'-monophosphate. PDE ... | 178,439 | [
-0.2970673,
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0.2246551,
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0.1920261,
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0.2224834,
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0.1369976,
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-0.7951163,
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-0.03736588,
-0.2267685,
0.8548144,
0.1236913,
-0.3328612,... |
Three muscle fibre types in the axial muscle of axolotl (Ambystoma mexicanum Shaw): a quantitative light- and electron microscopic study. | Morphometric analysis by light microscopy of p-phenylene-diamine stained semithin sections of axolotl tail muscle revealed differences in the cross-sectional area of the fibres and in the number of mitochondria and of lipid inclusions per fibre, and indicated the presence of three distinct types of fibres. The triparti... | 178,448 | [
0.1590178,
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0.2187785,
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0.0344185,
0.1636472,
0.2550142,
0.1390188,
-... |
Mitochondrial functional changes during hepatic hyperplasia and azo dye carcinogenesis. | Resting and active-state respiratory velocities, respiratory control, high amplitude volume changes, and latent ATPase activities were examined in hepatic mitochondria from rats fed 3'-methyl-4-dimethylaminoazobenzene (3'MeDAB) for production of liver tumors and from rats in three phases of liver regeneration subsequen... | 178,455 | [
-0.1925984,
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0.07067487,
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0.2699678,
0.3049503,
-0.04701568,
... |
Control of protein balance in hypertrophied cardiac muscle. | The levels of intracellular proteins are determined by a balance between their rates of synthesis and degradation. During the development of regression of cardiac hypertrophy, both of these rates can be expected to change. Possible control sites of synthetic and degradation processes are discussed in this article. The ... | 178,459 | [
-0.1172233,
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0.1463633,
0.3033088,
0.2272089,
-0.1106175,
... |
The effects of des-Asp1-angiotensin II on blood pressure, plasma aldosterone concentration, and plasma renin activity in the rabbit. | To examine the hypothesis that des-Asp-1-angiotensin II (angiotensin III) may be an important mediator of various responses to angiotensin II, both peptides were given sequentially at 25 ng/kg per min by systemic infusion to conscious rabbits, and the effects on blood pressure, plasma aldosterone concentration, and pla... | 178,463 | [
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0.08983935,
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0.2343366,
0.4712202,
0.2350402,
-0.06020931,
0.133141,
-0.1685926,... |
Regulatory properties of the citrate synthase from Rhodospirillum rubrum. | Citrate synthase, purified 600-fold from Rhodospirillum rubrum, is activated by KCl and inhibited by ATP and NADH; the effect of the latter inhibitor is completely counteracted by AMP and partially counteracted by KCl. | 178,526 | [
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0.1310105,
0.2352203,
0.1758288,
-0.00877387... |
Cyclic nucleotides in pancreatic islets. Tolbutamide- and arginine-induced insulin release. | With the use of isolated rat islet perfusion, levels of the islet cyclic adenosine 3' ,5' -monophosphate (cAMP) were compared with dynamic insulin secretion induced by tolbutamide and arginine. Tolbutamide elevated islet cAMP rapidly and augmented both glucose-induced islet cAMP levels and insulin secretion; arginine, ... | 178,555 | [
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0.05343978,
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0.04809674,
0.3531379,
0.2102036,
0.197638... |
Comparison of guinea pig cytomegalovirus and guinea pig herpes-like virus: pathogenesis and persistence in experimentally infected animals. | The pathogenesis of guinea pig cytomegalovirus (GPCMV) and guinea pig herpes-like virus (GPHLV) in guinea pigs was compared. Animals were inoculated with the two viruses by different routes and sacrificed after varying periods of time. GPCMV was consistently isolated from salivary gland 2 weeks postinoculation and ther... | 178,599 | [
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0.3454617,
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0.3510912,
0.4266125,
0.3258317,
0.3628654,
0.02623647,
0.0... |
Attachment of Mycoplasma pneumoniae to respiratory epithelium. | The attachment of radioisotope-labeled Mycoplasma pneumoniae to hamster tracheal rings in organ culture was examined by radioautography and liquid scintillation counting. Radioautographs of individual rings exposed for 8 h to (3H) thymidine-labeled virulent M. pneumoniae revealed a dense extracellular collection of emu... | 178,600 | [
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-0.4106596,
-0.2585452,
-0.07936909,
-0.09570314,
0.3997731,
0.07391228,
0.08979163,... |
Modified hemolytic plaque technique for the detection of bluetongue virus antibody-forming cells. | A hemolytic plaque assay was developed for the detection of antibody-forming cells to bluetongue virus (BTV). Sheep erythrocytes (SRBC), onto which BTV had been absorbed, served as the indicator of lysis due to the presence of BTV antibody-forming cells. The ratio of BTV to SRBC was found to be critical for optimum hem... | 178,602 | [
-0.06852428,
0.02095572,
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0.02969452,
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0.1736473,
-0.149085,
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0.3557646,
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0.1207518,
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0.1200622,
0.1069902,
0.3552186,
0.3432854,
0.1938302,
... |
Inhibition by zinc of hemolysis induced by bacterial and other cytolytic agents. | Zinc, cupric, and cadmium ions, in that order of effectiveness, inhibited lysis of washed, rabbit erythrocytes by the toxic bacterial product aerolysin. Hemolysis induced by a variety of other lytic agents was also inhibited by Zn2+ in approximately the same concentration as that, 0.33 mM, needed to inhibit aerolysin-i... | 178,604 | [
-0.2620384,
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0.07809667,
0.1413085,
0.1421601,
0.09804317,
0.1147379,
0.107742,
0.1696844,
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0.06400466,
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0.004401629,
-0.213807,
0.04432466,
0.1003953,
0.2808884,
-0.1164056,
... |
Quantitative cytophotometry evaluated as a method for analyses of herpes simplex viral deoxyribonucleic acid synthesis. | Feulgen deoxyribonucleic acid (F-DNA) microspectrophotometry was evaluated as a potential tool for quantification of herpes simplex virus type 1 (HSV-1) and 2(HSV-2) DNA synthesis in single cells. Since HSV DNA synthesis has been extensively studied using incorporation of radioactive precursors into viral and cellular ... | 178,608 | [
-0.2206999,
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0.2322392,
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0.3971412,
0.1134863,
-0.254215,
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0.08191771,
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0.01777298,
-0.1306654,
0.005889878,
0.02341907,
0.5480241,
0.2009286,
-0.07542137,
-0.1018312... |
Efficacy of phosphonoacetic acid on herpes simplex virus infection of sensory ganglia. | Treatment of mice with phosphonoacetic acid markedly reduced the incidence of latent ganglionic infection with herpes simplex virus when administered within 24 h after viral inoculation, but had no effect on an already established ganglionic infection. | 178,609 | [
0.002083753,
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0.1250287,
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0.01837261,
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0.07215761,
0.2251358,
0.1359849,
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0.1396111,
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0.4526608,
0.04661213,
0.1929993,
0.0460436... |
A new assay method for hydrogenase based on an enzymic electrode reaction. The enzymic electric cell method. | A new assay method for hydrogenase [EC 1.12.2.1] based on the enzymic electrode reaction of H2-H+ equilibrium has been established. The method is based on the experimental fact that the short-circuit current of the electric cell composed of an electrode with hydrogenase and methylviologen as the mediator of H2-H+ equil... | 178,640 | [
-0.1964439,
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0.007982265,
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0.3341432,
0.1672695,
0.05409829,
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0.2652602,
0.0685458,
0.1524147,
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0.3621758,
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-0.09777653,
0.575088,
-0.1533949,
-0.21335... |
Comparative specificity of geranylgeranyl pyrophosphate synthetase of Micrococcus lysodeikticus and pumpkin. | Comparative studies on the substrate specificity of geranylgeranyl pyrophosphate synthetase from Micrococcus lysodeikticus and from pumpkin seedlin revealed that geranyl pyrophosphate was the most active of the natural substrates for the pumpkin enzyme, whereas it was the least active for the bacterial enzyme. A marked... | 178,644 | [
0.1221377,
0.1521624,
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0.04846976,
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0.05811112,
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0.1716427,
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0.02519343,
0.141708,
0.0534044,
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0.1064544,
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0.4543703,
0.3613009,
0.3860904,
0.5255182,
0.1565291,
-0.2204143,
0.245... |
Nucleoside diphosphate kinase and the flagellar movement of glycerinated spermatozoa. | Nucleoside diphosphate kinase [EC 2.7.4.6.] of sperm flagella and Tetrahymena cilia is detected mostly in the outer fiber fraction, suggesting an association of the enzyme with the outer fiber microtubules. The enzyme does not catalyze transphosphorylation between microtubule-bound GDP and exogenous ATP. Even when undu... | 178,645 | [
-0.1510197,
0.1046008,
-0.1661126,
0.02850243,
0.1421443,
-0.2103059,
0.02591657,
0.1620949,
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0.2749624,
0.2643966,
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0.239611,
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0.2315456,
-0.4033907,
-0.04916845,
0.468834,
0.1719147,
-0.1126044,
0.15... |
Thermodynamic and EPR characteristics of a HiPIP-type iron-sulfur center in the succinate dehydrogenase of the respiratory chain. | In addition to the two species of ferredoxin-type iron-sulfur centers (Centers S-1 and S-2), a third iron-sulfur center (Center S-3), which is paramagnetic in the oxidezed state analogous to the bacterial high potential iron-sulfur protein, has bwen detected in the reconstitutively active soluble succinate dehydrogenas... | 178,656 | [
-0.1323875,
0.2012727,
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0.02212337,
0.01390931,
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-0.03066423,
0.0118558,
0.1603139,
0.002148803,
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0.007664005,
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0.06788585,
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0.120296,
0.1777655,
0.09961522,
0.1008975,
0.1815483,
0.2675255,
... |
The acute thyroidal response to iodixed oil in severe endemic goiter. | The acute changes in serum thyrotropin (TSH) triiodothyronine (T3) and thyroxine (T4), were measured in 14 subjects, 4 to 10 (mean = 6) days following intramuscular iodized oil injection. In 8 subjects with small or absent goiter there was a significant fall in T3 and a rise in TSH concentrations, suggesting an acute i... | 178,686 | [
-0.1186393,
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-0.3127952,
0.02255437,
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0.02061219,
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0.139162,
0.1302013,
0.2093986,
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0.03868398,
0.03365932,
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-0.09516694,
0.001560317,
-0.1184077,
0.1931791,
0.0431626,
0.3680544,
-0.03853541,... |
Use of biological characteristics to type Herpesvirus hominis types 1 and 2 in diagnostic laboratories. | Fifty clinical isolates of Herpesvirus hominis were typed by pock size on chicken embryo chorioallantoic membranes, sensitivity to heparin, and plaque formation on chicken embryo cell cultures. Of 19 isolates that were typed serologically, there was 100% concordance with respect to plaque formation. Pock size was incor... | 178,688 | [
-0.01499673,
0.1143446,
-0.3571925,
-0.09511294,
0.06691054,
-0.07312459,
-0.0830304,
0.3185408,
0.3707931,
-0.04044515,
0.2347804,
0.05644117,
-0.08292403,
-0.01688878,
-0.04301057,
-0.03486357,
-0.3422935,
0.07906895,
0.3841626,
-0.05012076,
0.3099251,
0.1927514,
-0.015... |
Influence on adipocyte plasma membrane bound protein kinase by feedback regulator. | Protein kinase, phosphodiesterase and adenylate cyclase of plasma membrane of adipocytes and the effect of the feedback regulator (FR) on these three enzymes was measured and compared. The basal level ratio of adenylate cyclase to phosphodiesterase to protein kinase was 1:1.9:3.0. Epinephrine and/or FR alters this rati... | 178,696 | [
0.03255839,
0.05759386,
-0.1672121,
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0.1762501,
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0.2131056,
0.3377033,
0.02259479,
0.05879444,
0.1744231,
0.05487399,
0.2300655,
0.3052916,
-0.4859505,
-0.09263541,
-0.4087361,
-0.221862,
-0.2883189,
-0.00138369,
0.6804765,
0.01555631,
-0.2139702,
... |
Age-related changes in the flight muscle mitochondria from the blowfly Sarcophaga bullata. | Flight muscle mitochondria have been isolated from female blowflies (Sarcophaga bullata) of different ages, alpha-Glycerophosphate and pyruvate-proline respiration rates increase during development. Only pyruvate-proline respiration declines toward senescence (30%). This decline can be overcome by ATP-NaHCO3. Cytochrom... | 178,708 | [
0.02347082,
0.02082624,
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0.02149609,
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0.08491805,
-0.2537228,
-0.2080447,
-0.2454773,
0.0414612,
-0.2154455,
0.09284126,
-0.0008700402,
-0.7086893,
-0.04420526,
-0.08325233,
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0.1934682,
0.07250342,
0.1638246,
0.2767784,
0.04... |
Endodermally-derived and neural crest-derived differentiation antigens expressed by a human lung tumor. | The plasma membrane antigens of an undifferentiated small cell (oat cell) carcinoma of the lung were studied by the indirect immunofluorescence method on frozen section substrates with a rabbit antiserum prepared to the tumor plasma membrane fraction. After appropriate absorption of the antiserum, at least two differen... | 178,792 | [
0.2151733,
-0.3365634,
-0.09836678,
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0.1761407,
0.1569097,
0.2090111,
0.1035758,
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0.3934775,
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-0.5933884,
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0.01535653,
0.2598899,
0.2492609,
-0.1245649,... |
Studies on the terminal stages of antibody-complement-mediated killing of a tumor cell. I. Evidence for the existence of an intermediate, T. | The mechanism of the terminal steps in the lysis of antibody-sensitized tumor cells by complement (TAC) was studied. It was shown that once complement has reacted, lysis proceeded even in the absence of fluid-phase complement. Transformation of TAC to dead cells was found to be at least a two-step process: one of the s... | 178,793 | [
-0.2292599,
-0.04631916,
-0.1874777,
-0.2213658,
0.1546864,
-0.137663,
0.09087835,
0.3977986,
0.09227727,
0.4155679,
0.06975663,
0.3380251,
0.09790588,
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-0.477796,
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0.05719639,
0.364123,
0.610638,
0.2794892,
-0.2414196,
0.1... |
Effect of murine cytomegalovirus on the in vitro responses of T and B cells to mitogens. | Both in vitro and in vivo murine cytomegalovirus (MCMV) infection depressed the responses of lymphocytes to both B and T cell mitogens. The possibilities that macrophages or nonspecific T cell inhibition of B cells might account for the depressed responses were eliminated. In vitro data suggested that B cell responses ... | 178,797 | [
-0.1269251,
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0.1274236,
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0.239077,
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0.1008128,
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0.1494845,
0.3795487,
0.3518031,
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0.0544254,
0.01122578,
0.4164347,
0.1934694,
0.03222705,
0.1136617,
-0.... |
Adrenocortical hydroxylase deficiencies in acne vulgaris. | To investigate the possible occurrence of partial 11- or 21-hydroxylase deficiences in acne, an androgen-dependent disorder, 11 women with chronic nodulocystic acne were subjected to a 24-hr infusion of ACTH and their urine analyzed for tetrahydro S and pregnanetrio. The results obtained were compared to those found in... | 178,807 | [
-0.1738303,
-0.07423367,
-0.1647087,
-0.1746093,
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-0.3409325,
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-0.09082605,
-0.0625805,
0.05425864,
0.3440706,
0.04494151,
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0.1059738,
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-0.2082276,
0.1614904,
-0.1220303,
0.1409617,
0.334309,
0.001074458,
-0.0874... |
The effect of sex on the quantity and properties of the very low density lipoprotein secreted by the liver in vitro. | Livers from normally fed male and female rats were perfused in vitro with different amounts of oleate, and the production and properties of the very low density lipoprotein (VLDL) were studied. The mobility of the VLDL in the zonal ultracentrifuge was dependent on the uptake of free fatty acid and on the sex of the ani... | 178,815 | [
-0.01605499,
0.1144933,
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0.2478544,
0.0770371,
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0.04140991,
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0.06990951,
0.07072372,
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0.1628904,
0.1357218,
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-0.2031709,
0.03781421,
0.1137826,
0.1458929,
0.1771635,
-0.1658248,
... |
Effects of sub-total gastro-intestinal pancreatectomy of the rat foetus. | Sub-total pancreatectomy in utero was performed in 18-day-old rat foetuses. Pancreatectomized, sham-operated and control foetuses were collected 3 days later and body weight, glucose and insulin levels in blood, and glycogen content and glucose-6-phosphatase (G-6-Pase) activity of the liver were determined. Pancreatect... | 178,817 | [
0.1135833,
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-0.4801832,
0.08506513,
0.2406746,
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0.02594615,
0.1123164,
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0.1079852,
0.2444893,
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0.09526765,
-0.2714523,
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-0.1121363,
0.2164129,
0.453536,
-0.05859682,
0.450417,
-0.09372533,
-... |
Antibodies to Epstein-Barr virus and cytomegalovirus in Guillain-Barre syndrome. | Twenty-three patients with Guillain-Barré syndrome (GBS) were investigated for serum antibody titres against Epstein-Barr virus capsid antigen (EBV-VCA), cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV1). The geometric mean EBV-VCA titre was 45 in GBS, compared with 15-22 in healthy adults and 60 in sarcoido... | 178,829 | [
-0.01557227,
-0.1741857,
-0.0505439,
-0.5154342,
-0.00916933,
-0.1645273,
-0.3373601,
-0.09311136,
-0.2626203,
0.3828605,
0.2797574,
0.02232927,
0.1979598,
-0.04477032,
0.1040732,
-0.1071814,
-0.451773,
-0.005923905,
0.1650802,
0.2642369,
-0.06833749,
0.1134995,
0.0500072... |
Experimental panencephalitis induced in suckling mice by parainfluenza type 1 (6/94) virus. I. Clinical and pathological features. | Intracerebral inoculation of two strains of suckling mice with 6/94 virus, a parainfluenza type 1 virus originally isolated from two patients with multiple sclerosis, produced clinical disease 1-2 weeks after inoculation. Of 528 animals inoculated, 33% died (26% of the ICR strain and 76% of the BALB/c strain) usually b... | 178,833 | [
-0.3040405,
-0.3367264,
0.01405148,
-0.3660877,
0.2718449,
-0.01208462,
-0.003341782,
-0.09878439,
-0.01695121,
0.0467014,
-0.05778225,
0.1353342,
0.01061742,
0.0643732,
-0.1960358,
-0.03965008,
-0.01136013,
0.2051236,
-0.02965434,
0.03371374,
-0.02725854,
0.4524016,
-0.0... |
Evaluation of mithramycin in the treatment of anaplastic gliomas. | A controlled, prospective, randomized study evaluated the use of mithramycin in the treatment of anaplastic glioma compared to a similar group of patients receiving best conventional care. From a total of 116 patients in the study, 96 were within the valid study group. All patients were operated on, had histological co... | 178,838 | [
-0.008394717,
-0.1066687,
-0.03839824,
-0.4190384,
0.182127,
-0.2892128,
0.005798568,
-0.2351285,
-0.1488774,
0.0465652,
0.02146696,
0.1580005,
0.2505658,
0.07630681,
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-0.1249254,
0.4697622,
-0.3512456,
0.3127418,
0.1133255,
0.08153835,
0.09700721,
... |
Gallium-67 uptake by a malignant fibrous histiocytoma: case report. | Avid 67Ga-citrate uptake was observed in a malignant fibrous histiocytoma of the mediastinum. The realtionships of the tumor to the heart and liver was shown by 99mTc-sulfur colloid liver-spleen scanning and 99mTc-pertechnetate angiography performed in conjunction with a 67Ga-citrate whole-body scan. This is the first ... | 178,841 | [
-0.3742375,
0.2236444,
-0.2449947,
0.06652259,
0.01512682,
-0.08643188,
-0.4540108,
-0.3686416,
-0.3031385,
0.2203315,
0.1629365,
0.3736995,
0.04224401,
-0.03103518,
-0.4188291,
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-0.1346784,
-0.03795492,
0.09448428,
-0.06487275,
-0.06642689,
0.2376445,
-0.061... |
Evaluation of a live, attenuated respiratory syncytial virus vaccine in infants. | Respiratory syncytial virus ts-1 is a live attenuated experimental vaccine which was administered intranasally to 25 infants 11 to 19 months of age. Clinical evaluation was carried out following a controlled, double-blind protocol which eliminated observer bias, assessed intercurrent illness, and was designed to detect... | 178,852 | [
-0.05891575,
-0.1039346,
-0.1570636,
-0.3827474,
0.04754968,
-0.2140662,
-0.3178192,
-0.3826215,
-0.05818519,
-0.2879667,
0.1589021,
0.2216371,
-0.03343577,
0.01088284,
-0.5452412,
-0.1555405,
-0.4065889,
-0.1482735,
-0.02876424,
0.2522134,
-0.1130274,
0.2827138,
-0.08365... |
Characterizatiion of rat genetic sequences of Kirsten sarcoma virus: distinct class of endogenous rat type C viral sequences. | The nucleic acid sequences found in DNA and RNA from rat cells which are homologous to Kirsten sarcoma virus have been characterized. The homologous sequences are present in multiple copies per diploid rat cellular genome in a variety of different rat cellular dna's. In certain cells that constitutively express only lo... | 178,897 | [
-0.05761866,
0.02771601,
-0.2203444,
-0.1473467,
0.3473985,
-0.2131342,
-0.4002571,
-0.09064651,
0.4028168,
0.3992765,
0.07032125,
-0.2406808,
-0.04789011,
0.08547455,
-0.2784855,
-0.1168267,
0.1094952,
-0.04699645,
0.2939494,
0.03317982,
0.3411377,
0.0175186,
-0.344133,
... |
Proteins of Yaba monkey tumor virus I. Structural proteins. | Yaba virus proteins were characterized by polyacrylamide gel electrophoresis. Electrophoresis of Yaba virion (proteins) dissociated by sodium dodecyl sulfate and 2-mercaptoethanol in continuous and discontinuous buffer systems yielded 37 polypeptide species by staining and by counting bands of radioactively labeled po... | 178,906 | [
-0.2199884,
-0.02220143,
-0.2701421,
0.06208676,
0.1031965,
-0.4048889,
-0.06894172,
0.07369292,
0.1091545,
0.05247065,
-0.04217547,
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0.04562227,
-0.1547163,
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0.3253904,
-0.3213019,
0.1109461,
0.1618935,
0.08268973,
0.1324668,
0.03103595,
-0.1458195,... |
RNA composition of Junin virus. | Junin virus grown in BHK-21 cells was labeled with [3H]uridine and highly purified by differential and isopycnic centrifugation. The RNAs extracted with phenol and analyzed by polyacrylamide gel electrophoresis were shown to be composed of four large species (33, 28, and 18S) and three small ones (4, 5, and 5.5S). This... | 178,925 | [
-0.08331306,
0.1723293,
0.05832143,
0.1451377,
0.2221638,
0.1227224,
-0.2427899,
-0.1251248,
0.3477187,
0.01406019,
0.1278516,
-0.308872,
-0.08739927,
0.1464462,
-0.4282854,
0.02298949,
0.2425422,
0.269431,
0.08296128,
0.3789476,
0.4038869,
-0.2228276,
-0.08912202,
0.07... |
Processing of mengovirus precursor polypeptides in the presence of zinc ions and sulfhydryl compounds. | The effect of zinc ions on the post-translational cleavage of mengovirus polypeptides has been examined. The cleavage of the "A" precursor, which gives rise to the capsid proteins, was the most sensitive at concentrations of zinc chloride from 0.1 to 1.0 mM. Beta-mercaptoethanol and dithiothreitol antagonized the zinc-... | 178,929 | [
-0.1407025,
0.1001505,
-0.5546223,
-0.2683204,
0.07116763,
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0.2022244,
0.09043627,
0.09899931,
0.1517595,
0.1965893,
-0.1085833,
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0.09754844,
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0.08365197,
0.4126335,
0.05621551,
-0.2233582,
... |
RNA synthesis in cells infected with herpes simplex virus. XII. Sequence complexity and properties of RNA differing in extent of adenylation. | Fractionation of polyadenylated RNA from cells infected with herpes simplex virus by affinity chromatography on columns of poly (U) immobilized on glass-fiber filters yielded three major classes of RNA-containing poly(A) chains with average lengths of 30, 50, and 155 adenylate residues [poly(A)30, poly(A)50, poly(A)155... | 178,932 | [
-0.06174831,
0.1474049,
0.03817271,
0.125104,
0.3325711,
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0.02056419,
0.3133283,
0.1888345,
0.01099542,
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0.1091212,
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0.04661746,
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0.02130609,
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-0.08269624,
0.7806724,
0.08721486,
-0.2052317,
... |
Effect of sex hormones on protamine inactivated and resistant postheparin plasma lipases. | Effects of estrogens and the synthetic anabolic-androgenic steroid, Oxandrolone, on extrahepatic (protamine inactivated) and hepatic (protamine resistant) lipases in postheparin plasma, were assessed in 15 subjects with familial hypertriglyceridemia. In six women receiving conjugated equine estrogen (1.25 mg/day), mean... | 178,980 | [
0.08010501,
0.1837819,
-0.2585877,
-0.1597736,
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0.2085678,
0.02413193,
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0.1774836,
0.1407582,
0.2513289,
0.205426,
0.08648517,
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0.2938155,
0.4341715,
-0.09661895,
0.06942189,
-0.1918334,
-... |
Mechanism of plasma cyclic AMP response to hypoglycemia in man. | The effect of insulin-induced hypoglycemia on plasma cyclic AMP levels was studied in normal volunteers, adrenalectomized, and sympathectomized subjects. Significant increases in plasma glucagon were observed in all groups. Normal subjects all had two- to threefold rises in plasma cAMP while no response was seen in any... | 178,982 | [
-0.1873784,
-0.1050323,
-0.3889967,
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0.2208953,
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0.1848748,
0.2043092,
0.219547,
0.03278778,
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0.005632512,
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-0.1874522,
-0.1289491,
0.0635052,
-0.1562671,
-0.0486329,
0.1909246,
-0.002584739,
0.182636,
-... |
Linear dose--response relationships after prolonged expression times in V-79 Chinese hamster cells. | The expression time for induced mutants resistant to 6-thioguanine, in V-79 Chinese hamster cells, was determined by respreading the cells in the selective medium, at various times after treatment. The length of the expression time for mutants induced by X-rays, ethyl methane sulphonate and ultraviolet irradiation was ... | 178,997 | [
-0.2190558,
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0.2858695,
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0.02749893,
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0.2513677,
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0.06878009,
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0.2396661,
0.6061988,
0.1411078,
0.09597672,
-0.01677641,... |
[Relation between quality of dietary protein, plasma corticosteroid concentration and various enzyme activities in liver and mucosa of small intestine]. | Comprehensive studies were performed in Wistar rats on the relations between the dietary protein quality and the function of the adrenocortical system. The authors determined: the increase in body mass, the urea and corticosteroid concentrations in the blood plasma, the GOT (EC 2.6.I.I.) and GPT (EC 2.6.I.2.) activitie... | 179,007 | [
0.2399996,
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0.1042147,
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0.3556395,
0.019684,
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0.3806985,
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0.2541956,
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0.111581,
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-0.06307443,
-0.06801136,
0.4198825,
0.02030125,
0.04833239,
-0.1159113,
... |
Coronary artery surgery. Operative technique and patient education. | Coronary artery surgery, the preferred technique for myocardial revascularization in patients with ischemic heart disease, promptly increases blood flow to areas of the myocardium distal to the coronary obstruction. CAS completely relieves angina in 90% of patients. The risk of 1 to 5% is decreasing as operative techni... | 179,067 | [
-0.118488,
0.1835357,
-0.5858656,
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-0.07985763,
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0.145685,
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-0.2346104,
0.2805491,
0.3730364,
-0.307809,
-0.4040249,
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0.08559471,
-0.5376658,
0.03092331,
-0.1603378,
0.04635426,
0.04846366,
0.04411339,
-0.00585084... |
Binding of insulin to isolated nuclei. | Specific binding sites for 125I-labeled insulin were detected in purified nuclei isolated from rat liver. Binding was rapid, reversible and directly proportional to the number of nuclei employed. Unlabeled native insulin, at concentrations as low as 1ng/ml, significantly inhibited the binding of labeled hormone, wherea... | 179,086 | [
0.04822841,
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-0.2807875,
0.118834,
0.01796888,
0.01298954,
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0.09676277,
0.01063968,
0.1748443,
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-0.155606,
0.03647165,
-0.09703325,
-0.3151776,
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-0.5381664,
0.1080253,
0.42789,
0.1437405,
0.4229299,
0.191466,
-0.09496547,
-0.34... |
Mapping of the three species of polyoma mRNA. | The polyoma mRNA's present in the cytoplasm of primary cultures of mouse kidney cells during lytic infection were characterized by sedimentation velocity analysis and by hybridization to polyoma DNA fragments generated by a specific endonuclease of Hemophilus parainfluenzae (Hpa II). | 179,087 | [
-0.1644799,
-0.2737765,
-0.2469526,
0.1383734,
0.08699656,
-0.1129583,
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0.1681293,
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0.1659509,
0.1745393,
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0.00527143,
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0.1597035,
0.51507,
-0.08646959,
-0.1522622,... |
Cholera toxin interactions with thyrotropin receptors on thyroid plasma membranes. | Unlabeled cholera toxin inhibits [125I]thyrotropin binding to thyrotropin receptors on thyroid plasma membranes. Maximal inhibition by cholera toxin does not exceed 40%, whereas unalbeled thyrotropin completely inhibits [125I]thyrotropin binding to these same membranes. Kinetic analyses of the binding data are compatib... | 179,095 | [
-0.2237615,
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0.01492302,
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0.1067108,
0.2071881,
0.1055738,
0.1388707,
0.2492943,
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-0.3129469,
-0.09855485,
-0.0818034,
-0.1761665,
0.2260467,
0.0600979,
-0.165102... |
Recruitment and discharge frequency of phrenic motoneurones during inspiration. | The discharges of 107 phrenic motor axons were recorded from cats under chloralose-urethane anaesthesia with spinal cords transected at T1 or with intact neuraxis. During inspiratory occlusions in spinal cats, each motoneurone was recruited at a mouth pressure constant at a given end tidal CO2; no motoneurone was recru... | 179,122 | [
0.2119005,
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-0.3047329,
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0.005486727,
-0.7260714,
-0.3169466,
-0.6908081,
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0.02247559,
0.07300629,
-0.3666226,
0.1618497,
0.1042006,
0.09698557,
-0.1766229,
-0.2439198,
-0.03801787,
0.09008633,
-0.02049081,
-0.1540477,
0.3501051,
0.0210080... |
Collagenase and elastase released during peritonitis are complexed by plasma protease inhibitors. | Peritoneal fluids from patients with diffuse peritonitis secondary to perforation of the appendix contained large quantities of collagenase and elastase. The enzymes, which existed in the form of complexes with plasma protease inhibitors, probably had been released from the granulocytes. The two enzymes had linked almo... | 179,159 | [
-0.1465514,
0.1514968,
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0.05150184,
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0.1623191,
0.1688189,
0.02111751,
-0.05588511,
0.06684189,
0.04244104,
0.1107203,
0.1443181,
-0.2706366,
-0.08960726,
-0.1233112,
0.1967905,
0.2218502,
0.2019486,
-0.1264278,
... |
[Therapeutic problems in the radiotherapy of bladder tumors]. | The indications of different radiation techniques are reviewed. Out of these, the interstitial therapy should be regarded more attentively in future, unless too large a tumor is present in the fixed part of the bladder. The spatial distribution of the dose during percutaneous megavoltage therapy depends on the tumor st... | 179,166 | [
-0.1663726,
-0.05508759,
-0.2001084,
0.04003178,
0.2442851,
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0.005398561,
0.2032842,
0.2311693,
0.3641581,
0.2213448,
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0.0429048,
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0.03365055,
0.06104679,
-0.0694677,
-0.02776671,
0.4784967,
0.2260843,
0.01187711,
... |
[Correlation between immunological reactivity and the fat-carbohydrate metabolism. Influence of phenformin]. | Based on the conceptions of the relationship between energy and adaptation-immunological systems a number of hormone-metabolic indices were compared with immune reactivity as evidenced by skin tests and rosette-formation reaction. It is shown that lowering of immunological indices in oncological patients is associated ... | 179,212 | [
0.3158564,
-0.09075047,
-0.2026459,
-0.07636387,
0.2616565,
-0.6242471,
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0.371735,
0.04387139,
0.2701561,
-0.1095436,
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0.1529991,
0.1695549,
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-0.4092631,
0.1805068,
0.1443441,
0.6520159,
0.3513465,
-0.1535583,
-0.3288836,
-0.... |
Mixed monomolecular films of chlorophyll and cytochromes. | Mixed monomolecular films of cytochrome (Cyt) and chlorophyll (Chl) were spread at a nitrogen-water interface. A large interaction is observed between reduced Cyt f and Chl a in a mixed film. Oxidized Cyt f and Chl a in a mixed film show little evidence for interaction. Mixed monomolecular films of Chl a with either re... | 179,234 | [
-0.2896444,
0.1441537,
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0.09345468,
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0.3561551,
0.06894755,
0.09558253,
0.3214486,
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0.3071173,
0.02749532,
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-0.3717547,
0.0133236,
-0.1666144,
-0.08660813,
0.407798,
0.07308378,
-0.03591504,
... |
Herpesvirus in bladder cancer. | A case of squamous cell carcinoma of the urinary bladder in which herpesvirus virions could be identified by electron microscopy is presented. The value of cytology in the recognition of the typical intranuclear inclusions which led to the initiation of further studies is emphasized. Recent evidence concerning the rela... | 179,255 | [
-0.2245598,
-0.1066966,
-0.3529052,
-0.0722276,
0.09023014,
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0.04586962,
0.06732524,
0.2884418,
0.2040497,
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0.03892499,
-0.4404968,
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-0.1277168,
0.2439503,
0.171604,
-0.09835745,
0.3585718,
0.2566532,
0.09910633,
... |
Turnover and aortic uptake of very low density lipoproteins (VLDL) from hypercholesteremic rabbits as a model for testing antiatherosclerotic compounds. | VLDL from hypercholesteremic (HC) rabbits display features which are suggestive of inherent atherogenicity. The lipid composition, compared to that of control VLDL, shows an enrichment of cholesterol esters, which have a very high 18:1/18:2 ratio in their fatty acids, and an increased sphingomyelin content, with decrea... | 179,294 | [
0.1612539,
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0.005573238,
-0.0268263,
-0.0580999,
-0.2329828,
-0.1180628,
0.3195797,
0.1888432,
0.3091521,
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0.4676271,
0.1593402,
-0.02555528,
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-0.2052112,
-0.08081758,
0.2645262,
0.7732263,
0.292545,
0.05016436,
-0.2230464,
... |
High volume screening procedures for hypobetalipoproteinemic activity in rats. | We describe high volume screening tests for hypobetalipoproteinemic agents in which compounds are administered orally to cholesterol-cholic acid fed (hypercholesterolemic( or normally fed weanling rats for 4 days. In these tests total serum cholesterol levels and heparin precipitating lipoproteins (HPL) are determined ... | 179,295 | [
0.2067265,
0.2132583,
-0.101476,
-0.2427936,
0.2025925,
-0.4184749,
0.07155269,
-0.03382504,
-0.04076158,
-0.1264405,
0.01073218,
0.442479,
0.3896324,
0.3439761,
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0.05117486,
-0.5887519,
0.007773759,
0.3108304,
0.009606718,
0.125421,
0.008535839,
-0.2038577,
... |
Blindness caused by photoreceptor degeneration as a remote effect of cancer. | Three postmenopausal women developed photoreceptor degeneration one to four months preceding or following discovery of an anaplastic tumor. Two patients had transitory visual obscurations and bizarre visual sensations. Ring scotomas progressed to severe visual field loss. Retinal arteries were markedly narrowed. Electr... | 179,323 | [
-0.03337082,
-0.227614,
-0.1839446,
-0.2813574,
-0.2337749,
-0.3927003,
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0.005223991,
0.1685571,
0.06157345,
0.1732532,
0.2020309,
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-0.07378986,
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-0.4896783,
0.1898276,
0.4328158,
-0.08778635,
0.3316455,
0.443302,
0.0148752... |
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