title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Lipoprotein pre-staining: comparison of nitroblue tetrazolium and Sudan Black B. | Nitroblue tetrazolium and Sudan Black B have been compared as pre-staining agents for human serum lipoproteins, using acrylamide gel gradients. Results from Nitroblue tetrazolium staining should be used with caution for low and very low density lipoproteins, and further work appears necessary on the reaction with alpha... | 174,838 | [
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Inheritance of xanthomatosis and hyper-beta-lipoproteinaemia. A study of 7 large kindreds. | In a study of xanthomatosis in the county of Ostfold, Norway (approximately 220,000 inhabitants), it was found that 20% (37 out of 185) of the probands belonges to seven large kindreds where xanthomatosis and hyper-beta-lipoproteinaemia segregated. Almost complete ascertainment (99%) of living subjects in the sibships ... | 174,850 | [
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Mucus-secreting carcinoid tumor in a colonic diverticulum: report of a case. | A mucus-secreting carcinoid tumor arising in a colonic (rectosigmoid) diverticulum is presented. Carcinoid tumors in colonic diverticula have not been previously reported. The presence of mucin and argentaffin granules in the same tumor cell is illustrated. The recognition of mucus-secreting carcinoid tumors is emphasi... | 174,873 | [
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[Bactericidal dosie-activity relationships with E. coli, K. pneumoniae and Staph. aureus (author's transl)]. | In investigations into the dosis-activity relationships of bactericidal antibiotics used against E. coli, K. pneumoniae and Staph. aureus four types of activity could be demonstrated. The penicillin type shows almost no improvement in bactericidal activity despite increasing the dosage above a certain level. An increas... | 174,881 | [
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Effects of hyperosmolarity on the cyclic AMP concentration and lipolysis of the adipocyte stimulated by adrenocorticotropic hormone. | The effects of ACTH on 3',5'-cyclic AMP (cAMP) levels and lipolysis were examined on isolated adipocytes incubated in either isosmolar or hyperosmolar media. The ability of ACTH to induce intracellular cAMP accumulation was greatly enhanced by incubating cells in hyperosmolar sucrose (100 to 400 mM) solutions. Hyperosm... | 174,896 | [
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5alpha-Dihydrotestosterone binding protein in rat ventral prostate; purification, nuclear incorporation, and subnuclear localization. | Treatment of cytosol from the rat ventral prostate with cold acetone (-20 degrees C) evoked a 8 approximately 10-fold increase in the binding capacity with 5alpha-dihydrotestosterone (DHT). Starting from the extract of acetone-dried prostate cytosol, some 400 approximately 600-fold purification of the DHT-binding prote... | 174,903 | [
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The reduction of plastocyanin by plastoquinol-1 in the presence of chloroplasts. A dark electron transfer reaction involving components between the two photosystems. | The reduction of plastocyanin by plastoquinol-1 was efficiently catalysed by disrupted chloroplasts or etioplasts in the dark. The reaction was inhibited by 2,5-dibromomethylisopropyl-p-benzo-quinone which inhibits photosynthetic electron transport between plastoquinone and cytochrome f. Evidence is presented that the ... | 174,911 | [
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New coenzymically-active soluble and insoluble macromolecular NAD+ derivatives. | Reaction in dimethyl sulfoxide of nicotinamide 8-bromoadenine dinucleotide with the disodium salt of 3-mercaptopropionic acid afforded nicotinamide-8-(2-carboxyethylthio)adenine dinucleotide, a new NAD+ analogue functionalized at the adenine C-8 position by an omega-carboxylic side chain. Carbodimide coupling of the la... | 174,913 | [
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Free and sulfoconjugated dehydroepiandrosterone, cyclic adenosime-3',5'-monophosphate, and free estriol in maternal and cord blood. | When free DHEA, its sulfatide, and sulfate were assayed in maternal plasma as well as in umbilical cord arterial and venous plasma, rather high concentrations were found in either fraction from cord arterial plasma, reflecting the fetal contribution not only of free DHEA and DHEA sulfate, but also of the lipophile ster... | 174,934 | [
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Autoradiographic study of the penetration of non-histone chromatin proteins into differentiating cells. | Attention has previously been drawn to a specific effect of NHCP on embryonic Pleurodeles cell differentiation. With a modified NHCP labelling technique, autoradiography has revealed a cytoplasmic concentration of labelled NHCP and has not revealed any difference between homospecific and heterospecific NHCP penetration... | 174,937 | [
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The plasmatic 11-hydroxy-corticosteroid response in the human to a synthetic octadecapeptide corticotrophin (C-41795-Ba). | The adrenal response as measured by the plasmatic changes in 11-hydroxy-corticosteroid (11-OHCS) concentration following the administration of a synthetic octadecapeptide (C-41795-Ba) was compared in 17 normal young males with that obtained with the commercially available tetracosactrin. C-41795-Ba polypeptide shows a ... | 174,989 | [
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Humoral immune responses of cats to mammalian type-C virus p30s. | Natural and experimental cat sera were tested in radioimmune precipitation assays vs purified p30s from FeLV, RD114 and MuLV. Antibodies with specificity for FeLV p30 comparable to hyperimmune sera from heterologous species but of low titer were found in a high percentage of normal cats from households with a high inci... | 175,024 | [
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Fibroblast surface antigen (SF): the external glycoprotein lost in proteolytic stimulation and maligant transfromation. | It was previously shown that the fibroblast surface antigen (SF antigen, SFA) is composed of polypeptides of high molecular weight 210,000 (SF210) and 145,000 (SF145) and that both of these decrease in quantity after transformation of the fibroblasts by Rous sarcoma virus (RSV). The present experiments show that SF210 ... | 175,031 | [
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In vitro induction of tyrosinase activity in goldfish (Carassius auratus L.) integument by ACTH and dibutyryl-cAMP. | Tyrosinase was first detected in melanoblasts by the DOPA-oxidase reaction in the presence of catalase in explants of goldfish integument after 12 hr culture with either ACTH (1IU/ml) or DB-cAMP (0.1mM). Melanin did not appear in the new melanocytes until 24 hr. The data indicate that the release of cAMP within the mel... | 175,039 | [
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Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126. | The polynucleotide ligase-catalyzed joining of the eight chemically synthesized deoxypolynucleotides (segments 19 to 26), comprising the nucleotide sequence 86-126 of the DNA corresponding to the Escherichia coli tyrosine tRNA precursor has been investigated. Joining was studied using various combinations of 3, 4, or l... | 175,057 | [
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Adenine nucleotide changes at initiation of bull sperm motility. | Testicular and cauda epididymal sperm were obtained via catheters previously implanted in the rete testis and proximal vas deferens of bulls and were used to examine the relationships among sperm motility, cyclic adenosine 3':5'-monophosphate (cAMP) level, adenine nucleotide levels, and rates of glucose and oxygen cons... | 175,061 | [
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Critical density for relaying in Dictyostelium discoideum and its relation to phosphodiesterase secretion into the extracellular medium. | The critical cell density for relaying in D. discoideum, N*, has been measured as a function of cell density, N, and time after harvesting, t. It has logarithmic dependence on N for 2.5 X 10(4)/cm2 less than N less than 7.5 X 10(5)/cm2 and saturates for N more than 1.0 X 10(6)/cm2. N* is an increasing function of time ... | 175,073 | [
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Fluorescence of tryptophan-containing peptides on paper or silica gel after treatment with formaldehyde, formaldehyde-ozone or formaldehyde-hydrochloric acid. | Sensitive and specific procedures for the chromatographic detection of tryptophan and tryptophan-containing peptides are described. Formaldehyde gas induces strong and characteristic fluorescence from tryptophan and peptides with NH2-terminal tryptophan residues on silica gel. On filter-paper, the detection of small am... | 175,081 | [
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Corticotropic action of an intra-nasally applied synthetic ACTH derivative. | The corticotropic action of a synthetic ACTH derivative, D-Ser1 Lys17,18-1-18ACTH, after intranasal insufflation of 1 mg of the peptide was evaluated in 14 normal volunteers. Plasma cortisol and urinary 17-ketogenic steroids and 17-ketosteroids rose significantly over control values in all subjects (P less than 0.001).... | 175,085 | [
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Responsiveness to glucagon in fetal hearts. Species variability and apparent disparities between changes in beating, adenylate cyclase activation, and cyclic AMP concentration. | Previous studies of the ability of the immature heart to respond to glucagon have yielded conflicting results. To test the possibility that the apparent discrepancies might be explained in part by species variability, isolated hearts of fetal mice and rats (13-22 days' gestational age) were studied under identical cond... | 175,087 | [
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Multifocal malignant histiocytoma. | The pathology of malignant histiocytoma has recently been defined and its malignancy confirmed beyond doubt. A unique example of this tumour is described, a search of the literature having failed to find a previously recorded case with a multifocal origin. | 175,097 | [
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EB virus antibody and infectious mononucleosis in a boarding school for boys. | A study of EB virus antibody was undertaken in a boarding school for boys between 11 and 18 years of age; 35% of boys had EBV antibody when first sampled and a small number acquired antibody each year. Some of these boys had had no recorded illness during the period before the first positive sample and some developed c... | 175,098 | [
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Regulation of the T-cell response to ectromelia virus infection. I. Feedback suppression by effector T cells. | Spleen cells and serum from mice immunized with ectromelia virus suppressed the immune response to infectious virus when transferred intravenously into recipient mice given an immunizing virus dose. The suppression was reflected in decreased cytotoxic T-cell activity directed against H-2 compatible virus-infected targe... | 175,126 | [
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[Specificity of 3 alpha, 20 beta-hydroxysteroid: nad+ -oxidoreductase (author's transl)]. | The enzyme 3 alpha, 20 beta-hydroxysteroid:NAD+ oxidoreductase (EC 1.1.1.53) catalyses the stoichiometric reduction of 20-oxo groups of C-21 steroids by NADH, and the non-stoichiometric oxidation of 3 alpha-hydroxy groups of 5 alpha-androstane derivatives by NAD. The activity of the enzyme towards the most important C-... | 175,129 | [
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Eye movements during REM sleep: the influence of personality and presleep conditions. | Male subjects scoring high (n=17) or low (n=14) on the Maudsley Neuroticism scale were randomly assigned to a positive (n=17) or negative (ego threat) (n=14) presleep condition and then slept a single night in the laboratory. The negative condition elicited significantly more rapid eye movement activity (REM density) t... | 175,146 | [
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The acetylcholine sensitivity of the surface membrane of multiply-innervated parasympathetic ganglion cells in the mudpuppy before and after partial denervation. | 1. The surface chemosensitivity to iontophoretically applied acetylcholine (ACh) of single nerve cells in the cardiac ganglion of the mudpuppy was examined. 2. Some synapses on the neurones can be recognized in the living preparation with differential interference contrast optics. Identified synaptic regions of the gan... | 175,155 | [
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Vidarabine therapy for severe herpesvirus infections. An unusual syndrome of chronic varicella and transient immunologic deficiency. | Six patients with severe herpesvirus infections were successfully treated with vidarabine. One patient had a previously undescribed syndrome of chronic cutaneous varicella infection of eight months' duration, associated with transient but complete duppression of lymphocyte response to conconavalin A. Other diagnoses we... | 175,176 | [
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0.08589336,
0.04528705,
0.3672237,
0.3616287,
0.1659314,
0.121908,
-0... |
[The Verner-Morrison syndrome. The clinical picture and pathologic anatomy]. | The Verner-Morrison Syndrome is a clinically defined entity caused by an islet cell tumor of the pancreas. More than 60 cases have been described so long. The syndrome is characterized by diarrhea, hypokalemia and hypochlorhydria. In addition to a diabetic disposition, raised calcium levels and skin alterations may be ... | 175,209 | [
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... |
Abnormally large lamellar bodies in type II pneumocytes in Chediak-Higashi syndrome in beige mice. | Lamellar bodies in type II pneumocytes are markedly enlarged in beige mice. The irregular shapes of some of these enlarged specialized lysosomes suggest fusion of smaller ellipsoidal bodies to form the giant organelles, consistent with the proposal of others for the mechanism of formation of abnormal lysosomes in Chedi... | 175,215 | [
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... |
Desmoid tumor associated with cystosarcoma phyllodes of the breast. | A case of desmoid tumor of 17 years' duration associated with cystosarcoma phyllodes of 17 months' duration is presented. Good initial response to radiation therapy of the desmoid tumor was shown. Poor response of cytosarcoma phyllodes to radiation therapy was noted. A comparison between the similarities and difference... | 175,220 | [
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Lung lamellar bodies lack certain key enzymes of phospholipid metabolism. | Palmitoyl CoA-glycerol-3-phosphate acyltransferase, phosphatidate phosphohydrolase, and phospholipase A were assayed in subcellular fractions of rat lung, including lamellar bodies, the putative site of storage and secretion of lung surfactant. The specific activity of each of these enzymes in lamellar bodies was relat... | 175,233 | [
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Alterations in levels and interrelations of plasma apolipoproteins induced by diet. | Diets high in carbohydrates increase the rates of hepatic secretion of VLDL in man. VLDL particles are secreted in greater numbers; they also tend to contain more triglycerides and to be larger in size. Comparable changes in intestinal secretion of chylomicrons and VLDL accompany fat absorption. We studied the metaboli... | 175,240 | [
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[Specific modification of phenylalanine:tRNA-ligases of E. coli MRE-600 with N-chlorambucilyl-14c-phenylalanyl-tRNA]. | N-Chlorambucilyl-[14C]phenylalanyl-tRNA was used for the affinity modification of phenylalanine : tRNA-ligase from E. coli MRE-600. It has been found that N-chlorambucilyl-[14C]phenylalanyl-tRNA selectively inactivates phenylalanine : tRNA-lagase that results in formation of a covalent bond between the tRNA derivative ... | 175,264 | [
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Virus infections and acute renal transplant rejection. | The date of onset of 360 acute renal transplant rejection episodes from 1969 to 1973 have been compared with the prevalence of various common viral infections and infections due to Mycoplasma pnuemoniae. A positive correlation was found for influenza B infections (r=0.43, p less than 0.01) up to 5 months before transpl... | 175,308 | [
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0.4851429,
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Insulinoma in a pregnant woman. | The case of a 37-year-old primigravida suffering from severe hypoglycemia due to insulinoma is reported. Diagnosis was established on clinical grounds by assessment of inappropriate insulin release. Laparotomy was performed by the 12th gestational week. A wide distal pancreatectomy was carried out, and histopathologic ... | 175,325 | [
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[Oxygen consumption and cytochrome oxidase activity of muscle tissue from the limbs of axolotls following restoration of regenerative capability suppressed by x-ray irradiation]. | The intensity of oxygen consumption and the activity of cytochrome oxidase have been studied in the homogenate, mitochondria and nuclei of the limb muscle tissue in axolotls after the suppression of regenerative ability by X-irradiation and its experimental restoration. Under the suppression of regenerative ability, th... | 175,338 | [
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0.1294804,
0.2174975,... |
[Antibodies against the Epstein-Barr virus, capsid antigen in children with malignant neoplasms (author's transl)]. | Sera from children were tested for antibodies to viral capsid antigens of Epstein-Barr virus. The method applied was the indirect immunofluorescence test. 25 sera from healthy donors were titrated as controls. In 14 patients with acute lymphocytic leukemia we found low levels, a tiny little girl with chronic myelocytic... | 175,342 | [
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0.2... |
Neonatal diagnosis of familial type II hyperlipoproteinemia. | Cord serum prebeta-beta-lipoprotein concentration was measured in a radial immunodiffusion assay in 303 randomly selected, full-term infants whose parental phenotypes were unknown. Six infants had elevated concentrations, that is above a cut-off limit of 197 mg/100 ml (97.5th percentile). Three of these infants suffere... | 175,344 | [
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Specific spin-labeling of transfer ribonucleic acid molecules. | The spin labels anhydride (ASL), bromoacetamide (BSL) and carbodiimide (CSL) were used to label selectively tRNAGlu, tRNA fMet and tRNAPhe from E. coli. The preparation and characterization of the sites of labeling of eight new spin-labeled tRNAs are described. The sites of labeling are: s2U using ASL, BSL and CLS and ... | 175,353 | [
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... |
Specific oligoribonucleotide synthesis using primer-independent polynucleotide phosphorylase. | Oligoribonucleotides of a predetermined base sequence beginning with adenylyl-3', 5'-adenosine at the 5' end have been synthesized in yields varying between 13% and 42%. The synthesis was carried out using primer-independent polynucleotide phosphorylase from E. coli in the presence of high concentrations of primer and ... | 175,364 | [
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Macrophage migration inhibition and lymphocyte stimulation with mammary tumor virus associated antigens in Balb/c mice. | Lymphocytes of MTV-negative Balb/c mice are sensitive to one or more antigens of MTV as determined by blastogenic transformation and migration inhibition assays. The lymphocytes from MTV-positive Balb/cfC3H mice are nonresponsive in these assays but become responsive after the mice have been implanted with MTV-positive... | 175,373 | [
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... |
Progesterone binding in rabbit oviduct and uterus. | Progesterone binding of high affinity with a dissociation constant of 10(-9) M was identified in cytosol of rabbit oviduct and uterus. Macromolecules with sedimentation coefficients of 7-8 S and 4-5 S were present. Progesterone receptor concentration was two to fivefold lower in the oviduct when compared with the uteru... | 175,377 | [
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... |
Diffuse cavernous hemangioma of the colon in the Klippel-Trenaunay syndrome. | Large, infiltrative cavernous hemangiomas of the distal colon were present in 3 children with the Klippel-Trenaunay syndrome, 2 of whom are the subject of this report. The lesion is manifested clinically as intermittent rectal bleeding starting in the first 5 years of life. The radiographic features include (a) varicos... | 175,397 | [
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Cholesterol and beta-lipoprotein on lipid inclusions and lysosomal and mitochondrial permeability of cultured heart muscle and endothelioid cells. | Cultured rat heart endothelioid cells were used to study the effect of beta-lipoprotein and cholesterol on the production and persistence of cellular lipid inclusions. Both heart endothelioid and muscle cells were used to study the effects of beta-lipoprotein with and without cholesterol or cholesterol esters on lysoso... | 175,420 | [
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... |
[Leukocytosis and polynucleosis in infectious disease]. | During bacterial infections, the intensity of the polymorphonuclear leukocytosis depends on the bacterium but also on the mechanism and extent of the infection. Polymorphonuclear leukocytosis is greater during pyogenic and anaerobic infections. It is due to deep suppuration, septicemia of thrombophlebitic origin, acute... | 175,454 | [
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0.06831088,... |
[Unilateral renal atrophy]. | The authors report 45 cases of unilateral renal atrophy. The circumstances of discovery are related to the urological symptoms: pain, hematuria, pyuria. On the other hand, hypertension is rarely the reason for consultation. Women are more affected than men. Intravenous urography, retrograde cystography and arteriograph... | 175,460 | [
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0... |
[Acute transformation in 45 cases of chronic myeloid leukemia]. | After a chronic phase, the average duration of which in this series was 38 months, the acute phase of myeloid leukemia was very short, not exceeding 7 months. The clinical signs which suggest an acute exacerbation are, in order of importance, increase in the volume of the spleen, changes in general health, fever. The b... | 175,489 | [
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... |
[Basal cell epithelioma and multiple fibroepithelial Pinkus' tumors in the lumbosacral region. Discussion of the precipitating role of previous radiotherapy treatment. Apropos of 4 cases]. | The authors report 4 cases of multiple tumors of the lumbo-sacral region with, on histology, a mixture of basal cell carcinomas and fibro-epithelial Pinkus tumours. They were struck by the fact that three of these four patients had received, in this region, radiotherapy numerous years previously. They discuss the role ... | 175,498 | [
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-0.1668778... |
Pancytopenia and "caillary leak syndrome" with infectious mononucleosis. | A 19-year-old man with documented infectious mononucleosis presented with pancytopenia and a megaloblastic bone marrow. He developed a "capillary leak syndrome" with an expanded plasma volume of 9,290 ml and normal right heart and pulmonary artery pressures. The patient had a dramatic recovery after corticosteroid ther... | 175,508 | [
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0.1383131,
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0.2171198,... |
Meigs' syndrome. A case report. | A case of Meig's syndrome is reported and the rarity of this condition is emphasised. The need for exploratory laparotomy in patients with solid ovarian tumours associated with ascites and pleural effusion, and free of malignant cells, is stressed. | 175,510 | [
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0.0567... |
Dynamics of estrone glucosiduronate metabolism in dogs. | Interest in the metabolism of estrogen conjugates has been increased by the recent demonstration that some of these conjugates can be hydrolysed in vivo, and are thus a source of physiologically-active circulating estrogens. In this report the metabolism of the quantitatively important conjugate estrone glucosiduronate... | 175,526 | [
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-0.1341... |
Attempts to induce tubular deformations and subsequent mixed tumours from organotypic cultures of mouse renal mesenchyma. | With the aim of expanding knowledge on the pathogenesis of nephroblastomata, an embryological organ culture system (Grobstein, 1956) was tested for its applicability to in vitro carcinogenesis experiments by using murine sarcoma virus (MSV-M) and 3-methylcholanthrene (MCA). Treatment of CBA/H-T6 mouse metanephrogenic m... | 175,592 | [
-0.1688828,
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0.4480717,
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0... |
[Isolation of "pregnancy-zone" proteins using immuno absorbents and study of possible enzyme activities]. | The purification of the pregnancy zone protein by means of immunoadsorbents is described. The pregnancy zone protein antibody was isolated from an absorbed rabbit antiserum and coupled with CNBr-activated sepharose. The pregnancy zone protein was isolated from pregnancy serum by the specific antibody cross-linked with ... | 175,612 | [
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0.2138584,
0.2689093,
-0.09689955,
-0.1342729,
... |
[The effect of arecoline on the structure of sleep and wakefulness in hens]. | In chronic experiments on hens, studies have been made on the role of cholinergic mechanisms in regulation of the cycles "awakefulness-sleep". A cholinomimetic, arecoline, was used which stimulates M-cholinoreceptive brain neurons. Arecoline was injected intramuscularly in a dose 0.2 mg/kg of body weight. It was shown ... | 175,619 | [
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0.1740142,
0... |
Ultrastructure of the Gunn rat substantia nigra. II. Mitochondrial changes. | The substantia nigra of hyperbilirubinemic (Gunn) rats was studied using light and electron microscopic techniques. PAS-positive inclusions were observed within the neuronal somata of animals 2 to 12 weeks old. Incubation of tissue sections in 0.5% diastase inhibited most of the positive PAS reaction, thus indicating t... | 175,634 | [
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-... |
External and interstitial radiation therapy of carcinoma of the oral tongue. A review of 32 years' experience. | In 204 patients with squamous cell carcinoma of the oral tongue treated with radiation therapy, the most significant prognostic factors appeared to be the presence of neck lymph node metastasis on presentation and the status of the disease three months after treatment. The most common site of failure was the primary le... | 175,668 | [
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0.09554577,
0.05143363,
0.1624826,
0.1598015,
0.2272292,
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Volume and time factors in interstitial gamma-ray therapy. | The two suppositions which have dictated time-dose and volume relationships in interstitial gamma ray implantation have been examined in the light of recent publications. The first of these assumptions, that total dose reduction is required when the dose rate exceeds 6,000-7,000 rads in seven days, does not appear to b... | 175,676 | [
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0.3506268,
0.190426,
0.06641024,
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Successful intravenous cholecystocholangiography in the jaundiced patient using meglumine iodoxamate (Cholovue). | A clinical trial of meglumine iodoxamate (Cholovue) for intravenous cholangiocholecystography in 18 patients with elevated levels of serum bilirubin was performed. Ten to 30 cc of a 40% aqueous solution of the agent were given intravenously over a ten minute period and roentgenographic examinations conducted to documen... | 175,687 | [
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Biliary ascariasis in children. | The ascaris is a common human parasite and has a world wide distribution. In areas where it is endemic, biliary complications are common. In our locality it occurs mainly in children, presenting with upper abdominal colicky pain usually without jaundice. We have analyzed the positive roentgenological findings of 67 cas... | 175,704 | [
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0.1021958,
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Efficacy of pneumogynecography in the diagnosis of Meyer-Rokitansky-Küster-Hauser syndrome. | Twelve patients with Meyer-Rokitansky-Küster-Hauser syndrome were examined by means of pneumogynecography. The results obtained disclose the great diagnostic value of the method in this disorder. | 175,711 | [
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0.4745846,
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0.241717... |
Complications of percutaneous transaxillary catheterization for arteriography and selective chemotherapy. | This report enumerates and analyzes the complications of percutaneous transaxillary catheterization encountered in 200 consecutive patients undergoing diagnostic arteriography, and 20 consecutive patients who had catheter placement for selective chemotherapy. Diagnostic arteriography led to minor complications in eleve... | 175,708 | [
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0.1078884,... |
Computerized reconstructive tomography applied to breast pathology. | Breast tumors can be clearly defined from the surrounding breast parenchyma by the use of computerized reconstructive tomography. Certain types of fibrocystic mastitis also can be distinguished from tumors, but other types of fibrous mastitis and probably fibroadenomas may not be distinguishable from tumors unless cont... | 175,710 | [
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Microfilament bundles in antheridial nuclei of Achlya ambisexualis E 87. | This is the first report of intranuclear microfilaments within gametangial nuclei of oömycetous fungi. Longitudinal sections of four to six microfilaments were frequently observed in meiotic antheridial nuclei of Achlya ambisexualis. Each microfilament measured approximately 7--10 nm in diameter. Spindle tubules (25 nm... | 175,750 | [
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The intramitochondrial location of cytochrome c peroxidase in wild-type and petite Saccharomyces cerevisiae. | Cytochemical and ultrastructural analysis of wild-type cells of Saccharomyces cerevisiae, grown aerobically in a glucose-limited chemostat, shows that cytochrome c peroxidase is localized between the membranes of the cristae, that is, in the intracristal space. This enzyme is thus positioned appropriately within the or... | 175,751 | [
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0.2927924,
0.2319112,
0.5131251,
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Fine structure of the pancreatic islets in domestic fowl with special reference to the cell type and secretion. | The pancreatic islets of domestic fowl were investigated by electron microscope. The following results were obtained. 1. The A islet is composed of a great many A cells and a few D cells. It also contained only a few B cells which are situated mainly along capillaries. 2. On the contrary, the B islet is composed of a g... | 175,756 | [
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Changes in the heart in chronic experimental alcoholism. | In studies on the effect of chronic experimental alcoholism on the heart, rats were given 15% (v/v) solution of ethyl alcohol ad libitum instead of water to drink for 8 months. Histologic examination revealed degenerative changes in the myocardial fibers, and histochemical examination diminished activity of oxidative e... | 175,759 | [
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[The specificity of intracellular changes in chick embryo blastoderm during the latent period of embryogenesis]. | Yolk inclusions, lipids and polysaccharides found in the chicken embryo blastoderm cells are utilized during the latent period of embryogenesis. The yolk outside the blastoderm is not utilized. A delay in the development of the embryo of first days of incubation is related to a switching over the metabolism from utiliz... | 175,769 | [
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0.6842377,
0.2912147,
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Characterization of a virus associated with epidemic conjunctivitis in Thailand. | A strain of virus, named the A-E strain, was isolated from a patient suffering from acute haemorrhagic conjunctivitis during an epidemic of the disease in Bangkok in 1972. The virus had the characteristics of an enterovirus but was not neutralized by any known enterovirus antiserum. Cross neutralization tests indicated... | 175,776 | [
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Further evidence for the concept of bovine plasma arylesterase as a lipoprotein. | Purified preparations of bovine plasma arylesterase were obtained by isoelectric focusing of enzyme prepared by (NH4)2SO4 fractionation of plasma and chromatography on DEAE-cellulose and Sephadex G-200. Although the high-density-lipoprotein fraction (HDL2) of serum provides an alternative source of enzyme, the enzymic ... | 175,783 | [
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0.06... |
Subunit structure of human erythrocyte glycophorin A. | Glycophorin A is a sialoglycoprotein isolated from human erythrocyte membranes which seems to exist as stable dimeric complexes in the presence of sodium dodecyl sulfate. When analyzed by dodecyl sulfate acrylamide electrophoresis this molecule forms two PAS-stainable bands (PAS-U and PAS-2) which are reversibly interc... | 175,830 | [
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Studies on human serum high-density lipoproteins. Self-association of human serum apolipoprotein A-II in aqueous solutions. | Some of the solution properties of pure preparations of human serum high-density apolipoprotein A-II were studied by sedimentation equilibrium ultracentrifugation, conducted at different apoprotein concentrations and at several speeds. The concentration dependence of the apparent weight average molecular weight indicat... | 175,831 | [
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... |
Cyclic AMP formation and morphology of myocardial cells isolated from adult heart: effect of Ca2+ and Mg2+. | Adult rat heart cells were isolated by perfusion with a calcium-free phosphate buffer containing collagenase. Optimal conditions gave a high proportion of elongated cells. Isoprenaline increased cydic AMP content linearly, with ED50 (dose effective in 50% of the population) about 10(-7) M. Ca2+ made the cells spherical... | 175,847 | [
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0.02030208,... |
Characterization of the Ehrlich ascites tumor plasma lipoproteins. | 1. The lipoproteins of the Ehrlich ascites tumor plasma were separated into 3 distinct fractions, very low density, low density and high density lipoproteins by preparative ultracentrifugation combined with agarose column chromatography. 2. High density lipoproteins contained 74% of the total protein in the lipoprotein... | 175,849 | [
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[Ultrastructural study of a Masson's "humid meningioma"]. | The authors report the ultrastructural analysis of a Masson's humic meningioma. The tumor presents at the electronic microscopic examination every sign of secretive hyperactivity and does not show any degenerative characteristics. The existence of an important extracellular material rich in pre-collagenic fibres accoun... | 175,868 | [
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0.05263526,... |
Prosthetic restoration in congenital lower limb deficiency. A case study. | We presented a synopsis of a young girl with congenitally deficient limb who underwent seven corrective surgical procedures and fabrication of a specially designed and constructed prosthesis. The surgical procedures are detailed as in the total rehabilitation approach. We have provided plastic laminated orthoses and pr... | 175,872 | [
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0.2469608,
0.2634304,
0.07171241,
0... |
[DNA form of the genome of oncornaviruses]. | The oncornaviruses share several biological, biochemical, and structural properties that distinguish them from other RNA viruses. Rous sarcoma virus, a representative of avian oncornaviruses, manifests two major functions: cell transformation and virus replication. Both functions are independent, and are expressed sepa... | 175,870 | [
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... |
Hypothalamo-pituitary adrenocortical function in the rat after treatment with betamethasone. | 1 Hypothalamo-pituitary-adrenocortical (HPA) activity was suppressed in rats treated with betamethasone. 2 Recovery of normal HPA function occurred after corticosteroid withdrawl. 3 Although corticotrophin release was rapidly restored to its basal rate there was a delay in the return of the normal adrenocorticotrophic ... | 175,875 | [
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0.2855994,
0.05860227,
0.1046506,
0.0421580... |
3':5'-Cyclic-AMP phosphodiesterase activities in white and brown adipose tissues of cold-acclimated rats. | 3':5'-Cyclic-AMP phosphodiesterase (PDE) (EC 3.1.4.17) activity was measured in interscapular brown adipose tissue (BAT) and in white epididymal adipose tissue of rats acclimated to constant or fluctuating cold. Experiments were carried out on isolated adipocytes or tissue homogenates. In brown or white adipose tissue ... | 175,898 | [
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... |
Purification of Oidiodendron kalrai proteases. | Oidiodendron kalrai yeast-phase cells demonstrate proteolytic activity. Some of the proteolytic enzymes of the crude extract were purified by a combination of ammonium sulfate precipitation, Sephadex G-200, and diethylaminoethyl (DEAE) cellulose column chromatography. At least six proteins exhibiting a range of proteol... | 175,906 | [
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0.2339549,
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0.1... |
Signet-ring cell carcinoma of the breast. The mucinous variant of infiltrating lobular carcinoma? | Five cases of the type of mammary carcinoma that has been designated "signet-ring cell carcinoma" are presented. This tumor is characterized by the presence of numerous cells containing intracellular mucin, without large amounts of extracellular mucin as is seen in colloid (gelatinous, mucinous) carcinoma of the breast... | 175,913 | [
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0.1070848,
0... |
The epidemiology and virology of C-type virus-associated hematological cancers and related diseases in wild mice. | In several different populations of wild mice, observed over a 35-month period in laboratory geriatric colonies, a direct correlation was found between the prevalence and titer of spleen complement-fixing gs (p30) antigen and C-type particles in newly trapped healthy mice and a predilection to lymphoma and a hind leg p... | 175,918 | [
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0.3231168,
0.250853,
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0.0785949,
-0.2153095,... |
An approach to C-type virus immunoprevention of spontaneously occurring tumors in laboratory mice. | A review of our current progress in C-type virus vaccine research is presented. This includes the findings of C-type virus or its antigen expressions in every naturally occurring tumor of two strains of "low-incidence" laboratory mice, the BALB/cCr mouse and the NIH Swiss mouse. Vaccine preparation methods are describe... | 175,922 | [
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0.04204777,
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0.5465438,
-0.08701253,
0.276094,
-0.02018731,
... |
Epstein-Barr virus-malaria interaction models for Burkitt's lymphoma: implications for preventive trials. | Infections with both Epstein-Barr virus (EBV) and malaria have been implicated as causal factors in the pathogenesis of Burkitt's lymphoma (BL). Proposed trials of preventive measures for both infections are receiving serious consideration as possible means of establishing a causal relationship with BL. In this paper w... | 175,923 | [
-0.2698083,
-0.06730495,
-0.07014114,
-0.1273966,
0.07226484,
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-0.05331727,
0.104155,
0.1867559,
0.1712541,
0.1615085,
0.08011433,
0.02606899,
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0.1389828,
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0.3774714,
-0.01475032,
-0.08384... |
Natural mechanisms of controlling lymphotropic herpesvirus infection (Marek's disease) in the chicken. | Four categories of natural resistance phenomena against Mareks disease in chickens, i.e., maternal antibody, age resistance, genetic resistance, and natural immunization, are described. In nature, these forms of resistance probably act in concert through comlex interrelationships. The mechanisms are not well understood... | 175,926 | [
-0.3609194,
-0.2928677,
-0.08197515,
-0.2978478,
0.1195135,
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0.04915571,
0.01698841,
0.3390749,
0.1601263,
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0.2236994,
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0.008300734,
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0.2728638,
0.2864065,
0.0100811,
-0.2296414,
... |
The fine structural localization of testicular phosphatases in man: the control testis. | Electron microscopic cytochemistry was used to determine the localization of five phosphatase enzymes-glucose-6-phosphatase, inosine diphosphatase, thiamine pyrophosphatase, acid phosphatase, and adenosine triphosphatase-in control human testes. Glucose-6-phosphatase occurred in the endoplasmic reticulum and nuclear en... | 175,958 | [
0.1333575,
0.002305746,
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0.2374636,
0.2094842,
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0.2620553,
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0.1055549,
0.133052,
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0.1699799,
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0.1866012,
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0.03781379,
-0.0629937,
0.5389092,
0.3018595,
-0.1125596,
0.... |
Alkylation of meseenger RNA by dimethylnitrosamine. | Rats were treated with radioactive dimethylnitrosamine or methyl methanesulphonate and the alkylation of various RNA fractions was determined 4 h later. It was found that after administration of dimethylnitrosamine, hepatic messenger RNA (isolated by binding to oligo(dT)-cellulose) and nuclear RNA were alkylated slight... | 175,964 | [
-0.1052037,
0.2382228,
-0.03438203,
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0.2326659,
0.02461292,
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0.2025471,
0.2120318,
0.09234048,
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0.3461715,
0.1938835,
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0.02461617,
0.0127299,
0.177124,
0.4342084,
-0.09544253,
-0.002643823... |
[Early stimulation of protein kinase activity during hormonal meiosis reinitiation in starfish ovocytes]. | Total endogenous protein kinase activity has been compared in homogenates prepared from Marthasterias glacialis and Asterias rubens oocytes treated or not by 1-methyladenine, the hormone which triggers meiosis reinitiation. A 5 mn treatment at the threshold 10(-7) M concentration causes a significant increase (+ 20%) o... | 175,969 | [
-0.06534723,
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0.003316343,
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-0.5057888,
-0.05974561,
0.05813931,
0.1884935,
0.5245477,
0.0799426,
-0.28165... |
[Isolation of murine sarcoma virus not associated with XC plague forming leukemia virus]. | The N-type MLg cells transformed by B-tropic MuSV (WN1802B) produced defective MuSV without detectable among of MuLV; the focus formation by the culture fluid required the co-infection of exogenous MuLV. After one passage of the virus in MLg cells, we obtained a virus preparation which was capable of inducing foci with... | 175,971 | [
-0.3119484,
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0.01417058,
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0.003148355,
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0.146089,
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0.2840265,
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0.2322463,
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0.068759,
0.05826521,
0.0549745,
-0.07627458,
0.6479338,
0.03846844,
-0.06453248,
... |
Direct radioimmunoassay for serum estriol during pregnancy. | I describe an assay for serum estriol during pregnancy, which does not require prior extraction or chromatography of the serum. Fifty microliters of 20-fold diluted serum can be assayed to detect as little as 20 pg of estriol. For a 20 mug/liter serum estriol concentration the CV was 16%; for 100 mug/liter concentratio... | 175,980 | [
-0.124298,
0.1353152,
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0.2565756,
-0.08043363,
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0.1905586,
0.1906707,
0.1114165,
0.3196596,
0.1685288,
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0.4069963,
0.1322528,
0.08634247,
0.1769969,
0.1916846,
-0.121819,
-0.1... |
Head pain. | Head pain can be a challenging, difficult, and interesting diagnostic problem. A detailed history and carefully performed and directed physical and laboratory examination will aid in the complex differential diagnosis--which includes structural disease of the eye, ear, nose, throat, teeth; trauma; central and periphera... | 175,988 | [
-0.1905629,
-0.1736634,
-0.2022081,
-0.10046,
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0.1587306,
0.2097515,
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0.2674566,
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0.1411094,
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0.1726856,
0.04472352,
0.1256038,
0.1078629,
-0.1101346,
-0.2110133,
0.3... |
Histological studies of subcutaneous and intraperitoneal implants of trypsin-prepared dermal collagen allografts in the rat. | The possibility of using allograft collagen for the permanent replacement of lost or damaged connective tissues has been examined in the rat. The cellular components of skin, which are known to be of major importance in allograft rejection, were removed by treating skin with a solution of crystalline trypsin at 15 degr... | 175,985 | [
0.1088224,
-0.1133217,
-0.4113307,
0.08338998,
-0.1245128,
-0.2780766,
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0.1366799,
0.1883628,
0.1179395,
0.1033695,
-0.2379063,
-0.1428327,
-0.1746144,
-0.3054842,
0.08660425,
-0.08728791,
-0.1057439,
-0.05526448,
0.1534068,
-0.05492366,
0.3281766,
-0.1438089,... |
Norepinephrine-induced shift in levels of adenosine 3':5'-monophosphate and ATP parallel to increased respiratory rate and lipolysis in isolated hamster brown-fat cells. | 1. Isolated brown fat cells from hamster respond to added catecholamines with a temporary increase in respiratory rate and an extended lipolysis. 2. From experiments with catecholamines and alpha and beta-blockers, the receptors of these cells are classified as beta according to classical definition. 3. Norepinephrine ... | 176,028 | [
-0.06818406,
-0.04761647,
-0.4549508,
0.1057872,
0.4784223,
-0.286996,
-0.1975583,
0.2937062,
0.08328371,
-0.08566677,
-0.2142707,
-0.2893332,
0.2098735,
0.1105342,
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0.009077876,
-0.4849942,
-0.04917268,
0.1523705,
0.1101982,
0.2766399,
0.1117191,
-0.1662679,
... |
[Influence of lithium chloride on lipid metabolism]. | Lithium chloride was injected subcutaneously to mice (in amounts of 500 and 300 mg/kg) once a day for 10 and 15 days, and to rabbits in single doses via a tube into the stomach (in amounts of 400 and 850 mg/kg). After different time intervals following a single or course-wise administration of the compound the level of... | 176,062 | [
-0.06940378,
-0.02055076,
-0.1826215,
-0.1502125,
0.4885203,
-0.3290821,
-0.1795111,
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-0.3864273,
0.1784423,
-0.04816144,
0.05276731,
0.122179,
0.1732214,
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-0.04956765,
0.09280887,
-0.03944772,
0.328584,
0.2784503,
0.04539734,
-0.1147571... |
Virus-induced diabetes mellitus. IV. Genetic and environmental factors influencing the development of diabetes after infection with the M variant of encephalomyocarditis virus. | The M variant of encephalomyocarditis virus (EMC) infects pancreatic beta cells and causes the development of a diabetic syndrome in susceptible strains of mice. By examining four F1 crosses of susceptible and resistant strains of mice, we found that the development of diabetes after infection was inherited as a recess... | 176,076 | [
0.04787368,
-0.2335659,
-0.1747766,
-0.07484789,
0.2087097,
-0.125489,
0.0306408,
-0.02916341,
0.0304312,
0.09427264,
0.02358218,
-0.08627405,
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0.1545438,
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-0.05526066,
0.08283485,
-0.1216478,
0.1449182,
-0.02011793,
-0.02924424,
-0.140672... |
[Percutaneous recanalisation of chronic arterial occlusions (Dotter principle) with a new double lumen dilatation catheter (author's transl)]. | A modification of Dotter's transluminal recanalisation of stenoses and occlusions of the superficial femoral artery, and of stenoses of the iliac artery, is described. In this procedure the occluding material is compressed not by successive catheters, but by a catheter with a dilatable cover. This catheter consisted or... | 176,097 | [
0.1573601,
0.4657702,
0.1058264,
0.3428241,
0.5161589,
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-0.1543742,
-0.0186892,
0.31315,
0.3556943,
-0.04377973,
-0.1606811,
-0.007233316,
-0.02626066,
-0.1778023,
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-0.4914694,
-0.008503973,
-0.2234277,
-0.04300902,
0.1139815,
-0.185605,
-0.1893009,
... |
Activation of C55-isoprenoid alcohol phosphokinase from Staphylococcus aureus. I. Activation by phospholipids and fatty acids. | The activation of C55-isoprenoid alcohol phosphokinase by a variety of lipids has been investigated. A number of amphipathic lipids can serve as effective kinase activators. Both the nature of the polar and nonpolar groups are important, but kinase activation does not depend on any particular chemical structure or char... | 176,145 | [
-0.06249333,
0.2074942,
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0.163572,
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0.1588899,
0.1946519,
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0.159512,
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0.05955849,
0.05633151,
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0.1117852,
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0.3913424,
0.472585,
0.2666032,
0.01835882,
-0.... |
Studies on the chlorinating activity of myeloperoxidase. | Two methods were utilized to demonstrate the peroxidation of chloride ion to a free species (HOCl or Cl2) by myeloperoxidase. The peroxidase caused the volatilization of radioactivity from soultions containing hydrogen peroxide and [36Cl]NaCl, and catalyzed the formation of HOCl when solutions contianing these componen... | 176,150 | [
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0.2513017,
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0.03317142,
0.001084632,
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0.148485,
0.3119253,
0.2770449,
0.2249078,
0.04603634,
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0.42687,
0.07256972,
0.1854502,
0.01628023,
-0.1117732,
... |
Comparison of mode of activation of guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases from silkworm. | Guanosine 3':5'-monophosphate (cyclic GMP)-dependent protein kinase (protein kinase G) partially purified from silkworm pupae was selectively activated by cyclic GMP at lower concentrations. Nevertheless, the enzyme seemed to differ from adenosine 3':5'-monophosphate-dependent protein kinase (protein kinase A) with res... | 176,153 | [
0.04492145,
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-0.3646131,
0.009269381,
0.07538985,
0.1688584,
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0.1272279,
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-0.04224027,
0.6696882,
-0.0961338,
-0.02673762,
... |
Effects of epinephrine and insulin on phosphopeptide metabolism in adipocytes. | Isolated adipocytes, incubated in the presence of extracellular 32Pi to steady state 32P incorporation into cellular phosphopeptides, were exposed to hormones for 5 min. Epinephrine (10(-6) M) stimulated 32P incorporation into at least 12 major phosphopeptides, distributed in the cytoplasm, endoplasmic reticulum, and p... | 176,155 | [
-0.1129106,
0.0684385,
-0.3383568,
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0.02687609,
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0.2500521,
0.3107565,
0.2267099,
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0.1677063,
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0.1228716,
0.2782977,
-0.1791846,
0.01430697,
... |
Effect of angiotensin II on cyclic guanosine monophosphate and cyclic adenosine monophosphate in human plasma. | Infusion of alpha-adrenergic catecholamines increases plasma cyclic guanosine monophosphate (pcGMP), raising the possibility that the pressor effect of these agents may be mediated by cyclic GMP. We infused pressor doses of angiotensin II in 10 studies in 8 normal subject and measured pcGMP and plasma cyclic adenosine ... | 176,170 | [
-0.3149691,
0.009978417,
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-0.3429852,
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0.2692963,
0.02194479,
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0.06177439,
0.3547856,
0.1372453,
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-0.05868854,
0.08697535,
-0.2451213,
0.4063622,
0.1088865,
-0.06519163,
0.03340... |
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