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Further observation of Kashara isoenzyme in patients with malignant diseases.
The Kasahara isoenzyme of alkaline phosphatase was found in cancer tissues from patients with gastric carcinoma, maxillary carcinoma, pulmonary carcinoma, and carcinoma of the urinary bladder, in addition to hepatoma. This fact suggests that the Kasahara isoenzyme may not be a specific marker protein of liver cancer bu...
191,327
[ -0.00566264, -0.3610152, -0.2910278, -0.3865719, 0.1086755, -0.2051425, -0.4247052, 0.07448962, 0.07420062, -0.08603714, 0.06601996, -0.1453753, 0.02731265, -0.1853211, -0.6474367, 0.06349299, -0.3520474, 0.1584579, 0.5435321, -0.03002773, 0.2536324, -0.02624643, -0.19212...
[Burkitt's lymphoma].
The Burkitt's tumor is a neoplastic disease which occurs mostly in the tropics. Sporadic cases however are distributed all over the world. This undifferentiated lymphosarcoma predominates in children. Extralymphnodal in origin, quick growth and lack of pain are very characteristic signs. Unattended most of the patients...
191,341
[ -0.1944407, -0.07912391, 0.07563598, -0.243803, 0.04460508, -0.4678277, -0.4578903, 0.0549491, 0.01779257, 0.08778296, 0.3292232, -0.13052, 0.08216225, -0.147472, -0.477312, -0.2061319, -0.02113628, 0.1371441, 0.1520077, 0.1390509, 0.5863069, -0.09645555, -0.2349334, 0....
[Wilms tumor in hemihypertrophy].
The case of a 4-year-old boy with Wilms' tumor and hemihypertrophy is described. Wilms' tumors are frequently associated with congenital malformations of the urinary tract, with aniridia and hemihypertrophy. Hemihypertrophy is a relatively rare malformation (1:14000) in the common population, but in patients with Wilms...
191,342
[ -0.2158714, 0.0004836827, -0.0615869, -0.3099371, 0.04744564, -0.3092652, -0.3638659, -0.1045722, -0.1222775, 0.09132499, 0.3268426, 0.3555779, -0.06093714, -0.2937495, -0.4796284, -0.3934736, -0.439097, 0.3045121, 0.1351371, -0.2877032, 0.4115044, 0.07934209, -0.07667961...
The gross and histological findings in the liver of pigs with Aujeszky's disease.
The gross and histological changes were studied in the liver of young pigs naturally infected with Aujeszky's disease. In the majority of the cases examined it was possible to detect small necrotic foci, scattered throughout the liver parenchyma, which corresponded histologically with intralobular or plurilobular areas...
191,340
[ -0.1829485, -0.1036815, 0.1214566, 0.2160379, 0.2371997, -0.2690631, 0.001138109, -0.01393607, -0.1761385, 0.1537622, 0.1641934, -0.2091983, -0.08844332, -0.09935391, -0.1319034, -0.02450692, -0.1982541, 0.1845223, 0.3591004, -0.2234807, 0.2426969, 0.3491026, -0.05749783,...
Response of marmosets to experimental infection with Epstein-Barr virus.
The response of cotton-topped (CT) or white-lipped (WL) marmosets, inoculated with material containing Epstein-Barr virus (EBV), was studied. Twenty-five marmosets inoculated with 10(6)-10(8) cells from human or simian EBV-carrying lymphoblastoid cell cultures developed no detectable clinical disease. Transitory antibo...
191,357
[ 0.002697567, -0.245699, -0.1564128, -0.6407979, -0.01909145, -0.1728187, -0.3707705, -0.239392, -0.007407672, 0.1658989, 0.5405602, -0.06903335, -0.02309047, 0.005699422, -0.7869574, 0.01093727, -0.3635845, 0.2103701, 0.04659289, 0.4233955, 0.4141408, 0.3062989, -0.247462...
The presence of Herpesvirus Saimiri genomes in virus-transformed cells.
Herpesvirus saimiri (H. salmiri) -transformed cells contained both types of viral DNA, unique L-DNA and highly repetetive H-DNA. DNA from spleen and lymph-node autopsies of two tumor-bearing marmoset monkeys contained 0.14-0.75% viral L-DNA -AND 0.115-1.08% H-DNA. This amount of H-DNA would be equivalent to the presenc...
191,414
[ -0.1783675, -0.4227459, -0.1219073, -0.1506735, 0.2029995, 0.07199932, -0.2943556, -0.1048465, 0.31608, -0.03501854, 0.04952375, 0.1155374, -0.03879759, 0.1616421, -0.8747146, 0.2258285, -0.3350086, -0.04723315, 0.07432263, 0.08566538, 0.2331091, 0.0627193, 0.02567432, ...
FeLV epidemiology in Los Angeles cats: Appraisal of detection methods.
We investigated the reliability of the fixed cell indirect fluorescent antibody (IFA) peripheral blood smear test as an index of systemic infection with FeLV. Positive results with this test were found to correlate well with detectable FeLV p30 antigen in bone-marrow smears by IFA, in serum and tissue by competition im...
191,415
[ -0.05353972, -0.2341026, 0.04759976, -0.2483014, 0.007031311, -0.06115442, -0.03417024, 0.1210014, -0.03141259, 0.297533, 0.212208, 0.1202345, 0.3093015, 0.2122495, -0.1497689, -0.3267577, -0.4396529, -0.2307553, 0.2249062, 0.1115105, -0.399416, 0.2186998, -0.1212104, 0...
Biosynthesis of ferritin in rat hepatoma cells and rat livers. I. Synthesis and assembly of protein subunits of ferritin.
Cell fractions were prepared from ACI rat livers and from rat hepatoma cell clone M-5123-C1. Radioimmunoassays of ferritin and of its protein subunits in various cell fractions after biosynthetic labeling with [14C]leucine were done by means of ferritin-specific and subunit-specific rabbit antibody. In both ACI rat liv...
191,450
[ -0.04008489, -0.2228654, -0.263502, 0.1624928, 0.4038302, -0.1096826, -0.2501332, 0.2023168, 0.1832594, 0.4740282, 0.01869906, -0.2019739, 0.03930866, 0.1080289, -0.0209549, -0.2353103, -0.3924623, -0.1431146, -0.2832015, 0.1104984, 0.2169947, 0.1112261, -0.225397, 0.15...
Direct assignment of the cysteinyl, the slowly exchangeable, and the aromatic ring 1H nuclear magnetic resonances in clostridial-type ferredoxins.
We have directly assigned the 1H NMR corresponding to the cysteinyl protons, the slowly exchangeable protons, and the aromatic ring protons in the 1H NMR spectrum of Clostridium acidi-urici ferredoxin by isotopic labeling and 13C NMR decoupling techniques. We also show that the resonance pattern in the 8- to 20-ppm (fr...
191,457
[ -0.341414, 0.00538474, 0.06485304, 0.5315055, 0.1071033, -0.1966231, -0.1011465, 0.1563524, 0.05102046, -0.0122121, 0.149757, -0.003667653, 0.1339521, -0.1086054, -0.586466, 0.01830469, -0.3434445, -0.003399429, -0.1194223, 0.002414328, -0.04824725, 0.2538475, -0.1899223,...
Preferential usage of glycyl-tRNA isoaccepting species in collagen synthesis.
Chick embryo tRNA charged with [3H]glycine was incubated in an in vitro protein-synthesizing system using polysomes isolated from either chick embryo liver or calvaria. Using collagenase digestion to measure the fraction of protein synthesized which was collagenous, the results indicate that in the calvaria system appr...
191,461
[ 0.2356899, 0.1746895, -0.2998183, 0.1998556, 0.005730247, -0.4897389, 0.03183216, 0.01783233, 0.005181444, 0.3932141, -0.05284585, 0.108061, 0.05488259, -0.09449737, -0.08383536, 0.1463542, -0.2852616, 0.1544521, -0.2773149, 0.2088997, 0.4574866, 0.03358434, 0.04026167, ...
Cell-mediated immune responses in recurrent herpesvirus infections. I. Lymphocyte proliferation assay.
Studies in immunosuppressed and immunodeficient patients indicate that the cell-mediated immune response appears to be responsible for controlling reactivated herpesvirus infections. In this study, the various parameters of a herpesvirus (types 1 and 2) antigen specific lymphocyte proliferation assay were optimized and...
191,528
[ 0.002114491, -0.5020638, -0.2021204, -0.2030884, 0.09956948, -0.05351078, -0.05724971, 0.2929741, -0.04518024, -0.08927154, -0.01111945, 0.04444449, -0.158027, 0.3523035, -0.2966709, -0.290044, -0.2423405, 0.2657805, -0.01723939, 0.4008132, 0.3268703, 0.05513772, 0.013286...
Specificities of killing by cytotoxic lymphocytes generated in vivo and in vitro to syngeneic SV40 transformed cells.
Cell-mediated immunity to SV40-transformed C3H and C3H-SW cell lines was measured by using both 51Cr and 125IUdR release assays. Killing by cytotoxic cells generated on in vitro sensitization of immune spleen cells with syngeneic SV40 cells by either assay is specific for syngeneic SV40 transformants. Cytolysis mediate...
191,529
[ -0.06877828, -0.1259994, -0.1474374, -0.4134984, 0.09546007, -0.2240164, -0.2370643, 0.1571157, 0.4079908, 0.1993586, 0.08235472, 0.01047473, 0.03164103, 0.2487884, -0.60663, -0.124795, -0.3156973, 0.104635, 0.1044485, 0.3199306, 0.07832528, 0.117998, -0.1412487, -0.003...
A comparative study of detection methods for Aleutian disease viral antibody.
Four methods of detecting and quantitating mink antibody against Aleutian disease (AD) virus were compared. Counterelectrophoresis, modified, counterelectrophoresis, immunofluorescence, and complement fixation were performed blindly on 274 serum samples. All four methods were reliably specific for AD antibody. Immunofl...
191,533
[ -0.05735744, 0.1575825, 0.0389553, 0.07005791, 0.008313335, 0.03367857, -0.1722438, 0.2830092, 0.04110626, 0.1941002, 0.05561636, -0.1205313, 0.3229384, -0.2625095, -0.09823141, -0.08146648, -0.2905332, 0.03227231, -0.3167876, 0.3206348, 0.265713, -0.2459457, -0.2361973, ...
Cyclic AMP regulation of active chloride transport in the rectal gland of marine elasmobranchs.
Active transport of chloride in the salt secreting rectal gland of the dogfish Squalus acanthias is markedly stimulated by the addition of theophylline (0.01 to 5 mM) or dibutyryl cyclic AMP (0.05 mM) during in vitro perfusion. The effect occurs promptly and may persist for two hours. Specific hormonal effectors have n...
191,564
[ -0.1279271, -0.4248609, -0.3978281, -0.3421805, -0.213306, -0.3547181, -0.1448651, 0.07228052, 0.08666927, 0.001230665, 0.1382356, 0.03588509, -0.07351901, -0.03462694, -0.2163927, -0.1658424, -0.5287161, -0.001172428, -0.2900396, -0.09042973, 0.3709241, 0.0009660292, 0.0...
Fingerprint inclusions. Ultrastructural demonstration of muscle fiber type specificity.
Fingerprint inclusions were identified in the skeletal muscle of a child with severe hypotonia. The mean Z-line and M-line widths from each of 19 muscle fibers containing the fingerprint inclusions were calculated. The mean Z-line widths were 85-99 nm, and the mean M-line widths were 75-101 nm. According to out present...
191,570
[ -0.06744672, 0.01954679, 0.002461355, -0.2633596, 0.01158445, -0.08719386, -0.3676161, 0.005568507, 0.1407979, 0.1599485, 0.0917359, -0.008049029, 0.3829131, 0.3107396, -0.2388321, 0.07463816, -0.377098, 0.1023285, 0.1190137, -0.05046628, 0.4517023, 0.0850444, -0.01373347...
The effects of neomycin upon transmitter release and action.
These experiments were designed to determine the site and mechanism of action of neomycin on cholinergic transmission. These agents depressed the response of rat diaphragm preparations to phrenic nerve stimulation and to injected acetylcholine (ACh); however, equi-effective neuromuscular blocking concentrations of neom...
191,590
[ -0.07407198, -0.1547575, -0.2448145, 0.1165544, -0.3027999, -0.5059445, -0.3305441, -0.2893148, -0.07031932, -0.03695248, -0.06173101, -0.06289062, -0.02044163, 0.1247575, -0.5075122, -0.009006687, -0.6611771, 0.0774882, -0.3187972, 0.02331757, 0.2900493, 0.2465533, 0.385...
Cytotoxicity of ricinoleic acid (castor oil) and other intestinal secretagogues on isolated intestinal epithelial cells.
Epithelial cells were isolated from hamster small intestine by a technique of vibration and used to measure cytotoxicity in vitro of certain substances known to stimulate intestinal fluid secretion. These secretagogues have laxative properties and produce mucosal damage in vivo. Compounds tested were ricinoleic acid (c...
191,594
[ -0.2363782, -0.0461699, 0.1427304, -0.09299365, 0.171661, -0.2316417, 0.08810731, -0.03314009, 0.1043331, -0.0472614, 0.1597812, 0.03233296, -0.2746481, 0.09407058, -0.03900149, 0.2247587, -0.7390255, -0.1076554, 0.004550312, -0.004686146, 0.1299249, 0.1008381, -0.0240413...
Family therapy: using a transactional approach.
The family can be viewed as a natural group which includes a mutual influence phenomenon. Intervention follows relationship building and assessment and is geared towards helping the family members challenge and change dysfunctional coding, decoding and structural transactions which inhibit the family group from meeting...
191,600
[ -0.140334, 0.4181813, 0.01953332, 0.01998606, 0.401615, -0.2276189, 0.03111686, -0.07062775, 0.0465572, -0.1471626, -0.09986645, -0.3176564, -0.2372988, -0.1752098, -0.4142219, 0.1931768, -0.1002804, 0.2314431, -0.4795641, 0.1460897, -0.1584306, 0.2592472, -0.1725528, -...
Bis-basic-substituted polycyclic aromatic compounds. A new class of antiviral agents. 8. Bis-basic derivatives of carbazole, dibenzofuran, and dibenzothiophene.
A series of bisalkamine esters, bis-basic ethers, and bis-basic ketones of carbazole, N-ethylcarbazole, dibenzofuran, and dibenzothiophene was synthesized and evaluated for antiviral activity. The series also included two bis-basic alkanes of N-ethylcarbazole and one bis-basic carboxamide of dibenzofuran. Structure-act...
191,610
[ -0.4690461, 0.5068944, 0.08104656, -0.1189203, 0.09068757, 0.02924853, -0.3226411, 0.01864413, -0.08119758, 0.04834168, -0.1675796, -0.3746997, 0.4216246, 0.4748292, 0.04526897, -0.225368, -0.4605902, 0.3579497, 0.1917377, 0.5587806, 0.207414, 0.05289963, -0.1287036, -0...
Cell-free translation of RNA synthesized in vitro by a transcribing nucleoprotein complex prepared from purified vesicular stomatitis virus.
The RNA species synthesized in vitro by a transcribing nucleoprotein (TNP) complex of vesicular stomatitis virus (VSV) were translated with high efficiency in a fractionated cell-free system derived from reticulocytes. The use of TNP complexes isolated from VSV Indiana, VSV New Jersey, and Chandipura viruses showed tha...
191,633
[ -0.1302136, -0.09050737, -0.1866821, -0.432456, 0.03641585, 0.1027421, -0.1310438, 0.07113455, 0.1083706, 0.03661805, -0.09304759, 0.1400597, -0.0189953, 0.2320801, -0.131539, 0.2698204, -0.3075142, 0.01098131, 0.117424, 0.2069773, 0.6681535, -0.1982284, -0.1245934, 0.1...
Immunological reactivity of antisera to sodium dodecyl sulfate-derived polypeptides of polyoma virions.
A study was undertaken to produce antisera to sodium dodecyl sulfate-derived polyoma virion polypeptides. With the use of this antisera, it was possible to detect, by immunofluorescence, cytoplasmic synthesis of V1, V2, and V3 polypeptides at 18 h postinfection and subsequent transport to the nucleus by 22 h postinfect...
191,638
[ -0.004467858, 0.08502976, -0.2099002, -0.1366355, 0.06940705, -0.07225787, 0.1189755, 0.2542492, 0.1128097, 0.2385973, 0.2484971, 0.1256748, 0.170395, 0.01740059, 0.05034176, -0.2588992, -0.3052778, 0.09022815, 0.0948442, -0.1526384, 0.1789314, 0.01356699, -0.2454133, -...
Separate pathways of maturation of the major structural proteins of vesicular stomatitis virus.
Cell fractionation and protein electrophoresis were used to study the intracellular sites of synthesis and intermediate structures in the assembly of the virion proteins of vesicular stomatitis virus. Each of the three major virion proteins assembled into virions through a separable pathway. The nucleocapsid (N) protei...
191,640
[ -0.3667069, 0.05595332, -0.1742559, -0.2495404, 0.3081523, -0.2335404, -0.03598573, -0.006300273, 0.06414818, 0.1057303, 0.07388585, -0.1542871, -0.1949764, -0.0634652, -0.1358356, 0.04758322, -0.3485054, -0.07294279, 0.1546251, -0.08766735, 0.5463979, 0.2399902, -0.20274...
Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B.
In herpes simplex virus type 1 (HSV-1)-infected HEp-2 cells, amanitin added before or at various times after infection always reduced viral multiplication. Also, the three waves of transcription of HSV-1 DNA, which led to the synthesis of alpha, beta-, and gamma-polypeptides, were all sensitive to amanitin in HEp-2 cel...
191,658
[ -0.07303796, -0.4246545, -0.5809821, -0.1553475, 0.2070585, -0.10363, -0.2640818, -0.08531663, 0.3891021, 0.07384731, 0.04447121, -0.1196513, 0.0233509, 0.3384909, 0.02724703, 0.02034374, -0.2310601, 0.1780464, -0.03278067, 0.3501251, 0.3959591, -0.1877116, 0.03887353, ...
The effect of a short term saturated fat diet on the apoprotein composition and radioiodination properties of rat very low density lipoproteins.
The effect of a saturated fat diet on the apoprotein composition and radioiodination properties of plasma very low density lipoprotein (VLDL) was studied in rats. After feeding the diet for 10 days, the proportion of 125I attached to VLDL lipid decreased from 50% (control animals) to 8%, the remainder (92%) being bound...
191,720
[ 0.2163223, 0.2502028, -0.1212557, 0.01781192, 0.1648091, -0.3330926, -0.0101326, 0.1744612, 0.06415243, 0.2927837, 0.1152733, -0.07873486, 0.0985047, 0.02795949, -0.1135352, -0.1103248, -0.3234721, 0.04059786, 0.3294539, 0.2268962, -0.0660918, 0.4537689, -0.07062823, -0...
An extensive rotavirus outbreak in aboriginal infants in central Australia.
Faecal specimens were obtained from 92 Aboriginal infants admitted to Alice Springs Hospital during an extensive outbreak of gastroenteritis in the surrounding area in July, 1976. Specimens were examined for potentially pathogenic viruses, bacteria and parasites. Rotavirus proved to be by far the most common potential ...
191,738
[ -0.1762976, -0.06828314, 0.03038296, 0.02758475, -0.1118892, -0.1007767, -0.4016375, -0.03206677, -0.05930788, 0.1197906, 0.2131606, 0.4333748, -0.1132162, 0.1040985, 0.1797555, -0.1854951, -0.4981308, 0.309543, 0.3476036, -0.4343663, 0.08387927, 0.1965497, -0.1696669, ...
Interaction between parathyroid hormone and catecholamines on renal cortical cyclic AMP.
Parathyroid hormone (PTH) and catecholamines (CA) increased cAMP levels in isolated tubules of rat renal cortex. A rise in cAMP could be detected 10 sec after the addition of agonists, and it reached the peak in 30-60 sec and then decreased despite the presence of active agonists. Direct relationships exist between the...
191,763
[ 0.003314002, -0.08479221, -0.4409317, -0.01163199, -0.006049061, -0.3257352, -0.1429883, 0.3627202, 0.09632403, 0.08699778, 0.02346495, 0.06584624, -0.2827155, 0.111229, -0.7122551, -0.07705602, -0.3355295, -0.08746686, -0.2935345, 0.2657385, 0.429555, 0.04205988, 0.03065...
Lack of association between defective delinquents and antibody of herpesvirus hominis.
Several groups have reported a relation between herpesvirus hominis infection and certain psychiatric disorders. We have investigated herpes antibody levels in chronic criminal offenders who were diagnosed as defective delinquents and in criminals who were not defective delinquents. We found no difference in the freque...
191,768
[ -0.1079462, 0.09804296, -0.07855006, -0.1659218, 0.03239341, -0.06288344, -0.5684507, -0.0300394, -0.1107367, 0.1884044, 0.3468304, 0.2234855, -0.02925833, 0.372959, -0.3543044, -0.2388407, -0.1829419, 0.1830156, 0.09861556, 0.2363259, 0.3236096, -0.07555711, 0.00302567, ...
[Apolipoprotein abnormalities in low and very low density lipoproteins in a type V hyperlipemia (author's transl)].
Abnormalities in VLDL and LDL apolipoproteins have been observed in the serum of an 11 year old girl with a type V hyperlipoproteinemia (VLDL + chylomicrons). This was shown with polyacrylamide gel electrophoresis and also with two dimensional immunoelectrophoresis. The LDL contain peptides which are not found in norma...
191,781
[ -0.037041, -0.1561417, -0.01751667, -0.06477629, 0.3753385, -0.1843478, -0.3113349, 0.1755912, -0.005646921, 0.2378311, 0.3054012, 0.4717139, -0.0957984, 0.1513982, -0.4925555, -0.2901862, -0.4195398, -0.04389768, 0.06099197, 0.1213159, 0.1735117, 0.01189305, -0.2888158, ...
Separation of subclasses of human serum high density lipoproteins by zonal ultracentrifugation.
An improved one-step method for the preparative separation of three subfractions of high-density lipoproteins from normal human serum has been developed. It employs the method of rate zonal ultracentrifugation in a z-60 rotor using a discontinuous NaBr gradient in the density range of 1.0-1.4. The density gradients wer...
191,800
[ -0.1031547, 0.1691749, -0.229525, -0.1052464, 0.06457052, -0.2036604, -0.3071437, 0.1702308, 0.1254257, 0.4064744, 0.07500403, -0.3052554, 0.1251253, 0.2101989, -0.3469368, -0.1980084, -0.3293817, -0.1191411, -0.3305469, -0.03233385, 0.3460234, 0.008136841, -0.03095773, ...
Specific changes in the pattern of protein synthesis during meiotic maturation of mammalian oocytes in vitro.
High resolution two-dimensional electrophoresis has been used to examine the pattern of protein synthesis during meiotic maturation of mouse oocytes in vitro. Fluorograms of [35S]methionine-labeled oocyte proteins have revealed that meiotic progression from dictyate to metaphase II (meiotic maturation) is accompanied b...
191,814
[ -0.2758979, -0.07211884, -0.3410509, -0.2508391, 0.05611444, -0.1581995, 0.1902699, 0.07955027, 0.158188, 0.0263538, -0.04918619, -0.0117493, -0.1473407, 0.08866841, -0.2393875, -0.03417438, -0.5619972, 0.2406145, 0.1488091, 0.04150202, 0.3967271, 0.1893925, -0.06836193, ...
Binding and internalization of thrombin by normal and transformed chick cells.
Thrombin stimulates cell proliferation in cultures of normal chick embryo fibroblasts but not in cells transformed with Rous sarcoma virus. Analysis of medium conditioned by Rous-sarcoma-virus-transformed cultures demonstrates that these cells do not secrete molecules that can inhibit or inactivate thrombin. The intera...
191,817
[ 0.03880822, -0.05391732, -0.3650305, 0.0118546, 0.1089387, -0.3360166, 0.09021948, 0.04840125, 0.2447627, 0.3536155, -0.03229698, -0.01100869, -0.4059097, -0.1716547, -0.1379141, 0.1017509, -0.2060485, -0.1073957, 0.2240103, 0.3759771, 0.3557641, 0.2591343, -0.2484508, ...
Dissociation of increases in levels of 3':5'-cyclic AMP and 3':5'-cyclic GMP from induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in mouse epidermis in vivo.
A single application of 17 nmol of 12-O-tetradecanoyl phorbol-13-acetate (TPA) to mouse skin caused a marked (200- to 400-fold) induction of ornithine decarboxylase (EC 4.1.1.17, L-ornithine carboxy-lyase) activity in mouse epidermal and epidermal-dermal preparations. No change in the basal level of 3':5'-cyclic AMP oc...
191,821
[ -0.1278794, -0.3571435, -0.4186252, -0.4720558, 0.3324819, -0.2927088, -0.2253054, -0.07890914, -0.04802104, 0.03506756, -0.1884789, 0.007242628, 0.03065852, 0.2178527, -0.4655246, 0.2265957, -0.4090009, 0.03793801, -0.04899589, 0.3369629, 0.4877638, 0.4922872, -0.1457835...
Reduction of collagen biosynthesis in blood vessels and other tissues by reserpine and hypophysectomy.
Synthesis of collagen in the vasculature and other tissues of normotensive rats is markedly reduced by reserpine. Hypophysectomy produces similar effects. The effects of reserpine on collagen biosynthesis may be mediated through the hypothalamus.
191,825
[ 0.09693965, 0.04976002, -0.1636173, -0.1986154, -0.05470346, -0.4400953, -0.1492876, -0.09960383, 0.2214894, 0.3362964, 0.2876068, 0.1408067, -0.1922642, -0.1755725, -0.5786055, 0.1406866, -0.06356343, 0.1185137, -0.1507706, 0.0990701, -0.05030628, 0.02479546, -0.1797544,...
Surgical treatment of hemifacial microsomia. (First and second branchial arch syndrome).
A review of 17 patients operated upon for unilateral hemifacial microsomia, and followed for up to 18 years, clarifies several principles of management. The management is facilitated by dysplasia predominance grouping, with the major functional deformity dictating the sequence of repair. Our surgical goals are: (1) pro...
191,863
[ -0.265361, 0.2239864, -0.1631972, -0.3959173, 0.3374089, -0.2798564, -0.2550372, -0.4752506, 0.1519695, -0.02768273, 0.1476076, -0.1718152, -0.4852824, -0.2976899, -0.3645186, -0.2047236, -0.2881894, 0.1494405, -0.3362853, -0.5193752, 0.2623349, 0.04370123, -0.01056231, ...
Sleep-waking changes in cardiac arrhythmia in a coronary care patient.
A single case is reported in whom ventricular cardiac arrhythmias were related to the occurrence of polygraphically verified sleep. A strong relationship was found to exist between the heart rate in any one minute and the number of premature ventricular contractions, with higher rates associated with a greater number o...
191,867
[ -0.1051468, 0.184201, -0.4009117, -0.2337419, 0.09591635, -0.1164596, -0.1696431, -0.3596103, -0.2131463, 0.04888565, 0.1529851, 0.3936345, -0.4026104, -0.0455345, 0.08334374, -0.2235357, -0.6336884, 0.09286017, 0.3807953, -0.3916812, 0.1524596, 0.005122715, 0.1493673, ...
Angiographic assessment of gross anatomy of hepatocellular cardinoma: comparison of celiac angiograms and liver pathology in 100 cases.
Of 190 sets selective celiac and/or hepatic angiograms obtained in patients with hepatocellular carcinoma (HCC), comparison with gross anatomy of the liver was subsequently made by autopsy in 77 and by surgery in 23. It was found that the gross anatomy of HCC can be assessed with certain accuracy by careful interpretat...
191,872
[ -0.07522242, 0.2768359, -0.3985673, -0.04574174, -0.2374638, -0.1219167, -0.08954667, 0.12099, 0.0310693, 0.3542786, 0.1206761, -0.06749847, 0.09870079, -0.4183837, -0.0772331, 0.04125714, -0.4009473, 0.2539525, 0.2696255, -0.05650362, 0.5212988, 0.1464251, -0.1716043, ...
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
Prostacyclin (PGX) (57)-9-deoxy-6,9alpha-epoxy-delta5-PGF1alpha has been found to be a potent stimulator of cAMP accumulation in platelets than PGE1. The prostacyclin stimulation of platelet cAMP accumulation can be antagonized by the prostaglandin endoperoxide PGH2, and a PGH2-induced platelet aggregation is antagoniz...
191,876
[ -0.3114043, -0.02923212, -0.4466597, -0.2873013, 0.1946192, 0.06565911, -0.08922026, 0.2543789, 0.08724573, -0.07342306, -0.02817206, 0.1672838, -0.111185, -0.07708225, -0.5894638, -0.002599168, -0.4039681, 0.1014921, -0.1266703, 0.4754112, 0.264065, 0.3491932, 0.1196886,...
Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.
A hypothetical model of the active site of angiotensin-converting enzyme, based on known chemical and kinetic properties of the enzyme, has enabled us to design a new class of potent and specific inhibitors. These compounds, carboxyalkanoyl and mercaptoalkanoyl derivatives of proline, inhibit the contractile response o...
191,908
[ -0.09125919, -0.1279238, -0.31461, -0.03058637, 0.3239867, -0.002621736, -0.1347625, 0.1034429, 0.3091316, -0.1368685, -0.01811188, -0.06823641, 0.2938632, 0.01889126, -0.5869533, 0.1565363, -0.717743, 0.1771794, 0.1050046, 0.3021689, -0.03935025, 0.197622, -0.070253, 0...
Antigen-antibody reactions in rat brain sites induce transient changes in drinking behavior.
The septum or hypothalamus of rat brain was injected through implanted cannulas with antibody against membrane antigens in the rat brain or with antibody against exogenous soluble antigens (such as ovalbumin) followed by the specific antigen. Both immunological systems produced a moderate but highly significant decreas...
191,911
[ -0.09032696, -0.1962062, -0.005658039, 0.1476929, 0.1049362, -0.4483392, -0.3272511, -0.2250391, -0.02660409, 0.1251893, 0.4127363, 0.1131222, 0.1071625, -0.290265, -0.2554251, 0.2273691, -0.5330282, -0.1111642, 0.04459544, -0.02750641, -0.02902633, -0.002353854, -0.16182...
[Topographic diagnosis of hypertensive pheochromocytoma].
In a series of 9 cases of hypertensive pheochromocytoma, the author noted in five of them abolition of the lower abdominal skin reflex on the same side as the tumour. They were in four cases suprarenal pheochromocytomas and in the fifth case an ectopic paraganglioma of Zuckerland's organ. In 3 cases, the abolished refl...
191,920
[ 0.1153272, -0.3813882, -0.2302144, -0.1961948, 0.1596683, -0.2167717, -0.3653969, 0.1247642, 0.2170598, 0.1009133, 0.310906, -0.07837003, 0.1173175, -0.395342, -0.3849054, -0.18999, -0.4100996, -0.0242629, 0.07593568, -0.09116521, 0.1394116, 0.057028, -0.07067636, 0.213...
Predictors of the duration of infectious mononucleosis.
The clinical course of infectious mononucleosis was monitored in 122 patients to determine predictors of duration of illness. Gastrointestinal symptoms and palatal petechiae were associated with a prolonged recovery period. Multiple regression analysis of quantitative data identified the number of days from onset of sy...
191,934
[ -0.03933951, -0.4604282, -0.2661453, -0.2414578, 0.03364401, -0.1948101, -0.04931501, 0.2238939, -0.1315919, -0.07307418, 0.2162415, -0.07298887, 0.1883766, 0.3630704, -0.4526828, -0.007185872, -0.1746754, -0.01851565, 0.02237223, 0.1751474, 0.3871967, -0.1670089, 0.08308...
Viral infections in renal transplant donors and their recipients: a prospective study.
The majority of renal allograft recipients develop viral infections, usually with cytomegalovirus (CMV). Their source if virus has not been defined clearly; one possibility if the transplanted kidney itself. To explore this, prospective viral studies were performed on 28 living related donor-recipient pairs. Donors did...
191,948
[ -0.1183222, -0.0707804, -0.03488267, -0.09634413, 0.2776722, -0.3401279, -0.2253102, 0.0925554, -0.2185097, 0.001474904, 0.1166265, 0.2222085, 0.1900142, -0.114848, -0.307907, -0.3394563, -0.06427136, 0.06711685, -0.03910358, 0.2367158, -0.008033837, 0.09806994, -0.276721...
Endocrine dysfunction and slipped captial femoral epiphysis.
Five patients with concomitant endocrinopathy and slipped capital femoral epiphysis were studied in detail. One had diabetes and hypothyroidism, one had hypothyroidism, one had hypergonadotropic hypogonadism and two had a craniopharyngioma (one of whom had severe panhypopituitarism post-operatively). An additional seve...
191,998
[ -0.04249259, 0.03456905, 0.02150967, -0.3637246, -0.0561854, -0.2903096, -0.225027, 0.009258914, 0.1324295, 0.3578657, 0.3942476, 0.4122716, -0.4573315, -0.5124546, -0.2948113, 0.1762799, 0.2837488, 0.1218143, -0.2578926, -0.1373764, 0.08589302, 0.1205658, -0.06203498, ...
Pig kidney phosphofructokinase. Purification to homogeneity and qualitative basic characterization.
Phosphofructokinase has been purified from pig kidney by extraction with phosphate buffer at pH 8, followed by alcohol treatment, affinity chromatography on matrix-bound Cibacron blue F3G-A, and gel chromatography on Sepharose 6B. Using sodium dodecyl sulphate electrophoresis the enzyme was found to be homogeneous and ...
192,023
[ 0.04432902, 0.3014349, -0.3063225, 0.2394885, 0.4436656, 0.03084601, -0.1380903, 0.2728241, -0.1134965, -0.07189084, 0.08173455, -0.0213451, 0.06649847, 0.07441203, -0.3814477, 0.2631807, -0.4292961, 0.0382116, -0.07650328, 0.175363, 0.4675407, -0.1003801, -0.2050452, 0...
Anti-HBc titer in relation to the etiological role of hepatitis B virus in primary hepatocellular carcinoma.
The antibody to hepatitis B core antigen (anti-HBc) is belived to be a marker for natural infection with hepatitis B virus (HBV). In order to study the etiological role of HBV in relation to primary hepatocellular carcinoma (PHC), the anti-HBc in sera of 31 PHC patients was surveyed by the immune adherence hemagglutina...
192,028
[ -0.0425354, 0.1133431, -0.1152637, 0.1833523, 0.09399651, -0.167874, -0.0375745, 0.4347546, 0.1129685, 0.4916954, -0.0746332, 0.2391504, -0.1874558, -0.1108315, -0.2335739, -0.4112772, -0.0284123, 0.1482943, 0.2136714, 0.2518968, 0.1970327, 0.1035404, -0.1580981, 0.1709...
Role of prostaglandin E2 in the stimulatory effect of ACTH on ovarian blood flow.
It has been studied in dogs anaesthetized with chloralose-urethane whether Prostaglandin E2(PGE2) might act as a mediator of the stimulatory effect of ACTH on ovarian blood flow. Without any damage to the ovarian vessels, a heated thermocouple was inserted into the stroma of the ovaries and local blood flow was recorde...
192,030
[ -0.1216983, -0.1939581, -0.1249657, -0.2141854, 0.00200634, -0.3793635, 0.1179254, -0.04991901, -0.0189416, 0.1708596, 0.1769114, -0.2403594, -0.04832518, -0.1082172, -0.4471656, -0.01154281, -0.336842, -0.247679, -0.0518322, 0.4911951, 0.2256927, -0.04446013, -0.1414638,...
Some histological aspects of amyloid polyneuropathy.
Two sporadic cases of amyloid polyneuropathy with clinical features corresponding to the Portuguese type of this disease were studied. Histological examination of sural nerve demonstrated a marked loss of myelinated and unmyelinated fibres in the case 1 due to axonal degeneration, high content of fibers with segmental ...
192,036
[ -0.204737, -0.2009679, 0.3500451, -0.04862161, -0.1703554, -0.3733155, 0.08891918, -0.3689962, 0.0669059, 0.04330729, -0.09511209, -0.3149349, 0.07921285, 0.1177587, -0.1480667, -0.1347713, -0.1559141, -0.08398002, -0.05195473, -0.06208877, 0.03512128, 0.1613915, 0.136979...
Light and electron microscopic studies of "nude" mice CNS after subcutaneous administration of the E variant of the encephalomyocarditis (EMC) virus.
Sixteen 3 month old "nude" mice, 24 of their litter mates and 30 Swiss mice were injected subcutaneously with 0.1 ml suspension of the E variant of the encephalomyocarditis (EMC) virus. While the mortality rate of the litter mates and Swiss mice during 5-7 days after inoculation was more than 40%, none of the "nude" mi...
192,039
[ 0.02988735, 0.3285336, -0.2685755, -0.05976138, 0.1210493, -0.3318225, 0.1992268, 0.02514911, -0.345197, -0.2398475, -0.1469394, 0.2059118, 0.1332006, 0.4439674, -0.2184339, 0.1192378, -0.05083391, -0.109051, 0.1025425, 0.439319, 0.1435339, 0.5029175, 0.207556, -0.25981...
Changes of rat cerebellar guanosine 3',5'-cyclic phosphate by dopaminergic mechanisms in vivo.
Apomorphine produced a dose-dependent increase of the cGMP level in the cerebellum. Haloperidol and scopolamine completely prevented this increase, and reserpine reduced the increase to 50%. LSD elevated cerebellar cGMP, and this effect was also abolished by haloperidol. It is suggested that the primary site of action ...
192,051
[ -0.1508433, -0.2699231, -0.03646937, -0.3750947, 0.1172149, -0.2737683, -0.1531431, -0.4388771, -0.2311133, 0.1635716, 0.28226, 0.3793716, -0.1830177, -0.008383092, -0.400436, 0.09746383, -0.5798504, -0.3093611, 0.05317437, 0.1317065, 0.1823487, 0.08530291, 0.1293462, 0...
Repartition and drug sensitivity of dopamine and L-isoproterenol-sensitive adenylate cyclases in rat brain homogenates.
The characteristics of dopamine, 1-isoproterenol, and d-LSD stimulated adenylate cyclases were studied in homogenates of fresh or frozen tissues. In rat striatum, when the assay was done in the presence of 1 mM MgSO4, dopamine (10(-4) M) stimulated the enzyme activity by 3.5-fold. This effect was completely blocked by ...
192,054
[ 0.06406936, -0.2213023, 0.1087666, 0.02844736, 0.18023, -0.4526244, -0.3176338, -0.1764694, 0.07266415, -0.1625226, 0.1307558, 0.1501572, 0.002870392, 0.3576874, -0.6495498, 0.06996378, -0.63283, 0.1852657, 0.03919099, 0.3111852, 0.321079, 0.1777545, 0.07549787, -0.2109...
Primary benign solid tumors of the liver.
The benign solid primary tumors of the liver separate into three major groups: (1) the most common lesions--small, nodular tumors, often found incidentally with histologic features suggesting a reactive etiology, that never rupture or metastasize, that seem to grow most rapidly in children and pregnant women, and that ...
192,098
[ -0.2178555, 0.2416216, 0.04770079, -0.3178325, 0.02081752, -0.3352966, -0.2667666, 0.006598221, 0.3385302, 0.04028873, 0.05325921, 0.1233537, 0.08298033, -0.2545128, -0.6016034, -0.1511665, -0.2218473, -0.07798824, 0.176304, 0.1661707, 0.07385926, 0.0171021, -0.3892122, ...
Demonstration and quantitation of immunoglobulins in bovine serum, follicular fluid, and uterine and vaginal secretions with reference to bovine viral diarrhea and infectious bovine rhinotracheitis.
Immunoglobulin concentrations (IgG, IgM, and IgA) in bovine serum, follicular fluid, and uterine and vaginal secretions were determined. The specificities of IgG, IgM, and IgA for virus-neutralizing antibody against bovine viral diarrhea (BVD) and infectious bovine rhinotracheitis (IBR) viruses were also examined. High...
192,113
[ -0.2096923, -0.04108994, 0.1748576, -0.142498, 0.02097546, -0.3621833, 0.1947874, 0.1195498, -0.3986508, -0.08243935, 0.4254139, -0.1552526, 0.1324001, 0.2980224, -0.07207038, -0.2248674, -0.2843305, 0.1573274, -0.1119464, 0.03046043, -0.002798505, -0.0830162, 0.02570232,...
Conjunctival impression cytology.
A new technique is presented using impression of the conjunctiva with a plastic device to study the conjunctival response in various conjunctival disease states. When used with a rapid acting stain the impression technique proved to be accurate, reproducible, and nondestructive when compared to the standard spatula scr...
192,184
[ -0.2658863, -0.2285605, -0.1366836, -0.3676634, -0.07719684, -0.07070687, -0.3007982, 0.07468893, 0.5905697, -0.03975871, -0.005947449, 0.09776987, 0.04014245, 0.3112087, -0.0180162, -0.2192508, -0.0790019, -0.0136785, -0.2115869, 0.0506929, 0.1461181, -0.04871044, 0.0167...
A phosphodiesterase in rat kidney cortex that hydrolyses glycerylphosphorylinositol.
1. A phosphodiesterase, active at an alkaline pH, is present in the outer cortex of rat kidney and hydrolyses glycerylphosphorylinositol into glycerol and phosphorylinositol. Some inositol cyclic phosphate can also be formed indicating that the enzyme can act as a cyclizing phosphotransferase. 2. The enzyme is stimulat...
192,216
[ -0.2014825, 0.01222108, -0.2858807, -0.1810163, 0.002750215, -0.08023766, -0.1572112, 0.1240091, 0.01761489, -0.06851823, 0.05299507, 0.2090398, 0.1229759, 0.1505246, -0.7921162, -0.08574075, -0.398183, -0.0323055, 0.03669107, 0.4426756, 0.2491001, 0.306282, -0.08328553, ...
Effect of thyroliberin on the concentration of adenosine 3':5'-phosphate and on the activity of adenosine 3':5'-phosphate-dependent protein kinase in prolactin-producing cells in culture.
1. The effects of thyroliberin were studied in cultured rat pituitary-tumour cells that synthesize and secrete prolactin (the GH4C1 cell strain). 2. Prolactin and cyclic AMP were measured by radioimmunological methods, and a cyclic AMP-dependent protein kinase was characterized by using histone as substrate. 3. Prolact...
192,221
[ 0.1079277, -0.4548943, -0.22272, -0.370745, 0.145773, -0.1503727, 0.1801479, 0.08453871, -0.103127, 0.3670856, 0.01276204, 0.2758636, -0.3234964, -0.1821475, -0.2498203, 0.04874263, -0.328868, 0.141377, 0.0246378, 0.01117822, 0.6093585, 0.3144515, -0.161538, 0.05394929,...
Surface components involved in virally mediated membrane changes.
1. Virally mediated permeability changes are not brought about by neuraminidase or other enzyme. They are not mimicked by local anaesthetics such as benzyl alcohol or dibucaine. 2. Virus induces an increase in the exchange rate of membrane-bound Ca2+. The temperature-dependence, and sensitivity to concanavalin A, of th...
192,222
[ -0.1330616, -0.4500109, -0.4933506, 0.03287377, 0.02241597, -0.4161415, -0.2273396, 0.01177983, 0.1693567, 0.358024, 0.1465285, -0.1537876, 0.2267583, -0.04908505, -0.2235967, -0.1934235, -0.3634634, -0.01742183, 0.1246869, 0.2055406, 0.4524812, 0.03107286, -0.2517951, ...
The actions of cyclic AMP, its butyryl derivatives and Na butyrate on the proliferation of malignant trophoblast cells in vitro.
Cyclic AMP, and its derivatives N6-monobutyryl cyclic AMP and dibutyryl cyclic AMP, have been found to inhibit the proliferation of trophoblast cells of the BeWo cell line in vitro. Sodium butyrate (1 mM), a possible degradation product of the butyrate derivatives, also inhibited cell proliferation, giving similar grow...
192,258
[ -0.1167145, 0.03857954, -0.4261577, -0.03627908, 0.3429537, -0.2649419, -0.1797701, 0.1459364, 0.07051954, 0.02199662, -0.2748122, -0.2510327, -0.1600846, 0.4060035, -0.1904985, -0.2425231, -0.3629806, 0.3529997, -0.1804211, 0.3004186, 0.2646405, 0.4400668, -0.1354884, ...
Triacylglycerol and very low density lipoprotein secretion into plasma of squirrel monkeys.
We determined the effects of varying the types and level of dietary fat and cholesterol on the increase in plasma total triacylglycerol concentrations after injection of Triton WR-1339, an inhibitor of lipoprotein lipase, into monkeys that had been subjected to an overnight fast. The monkeys that had been treated with ...
192,300
[ 0.1510928, -0.1887066, -0.1652197, -0.355812, 0.2122165, -0.4057336, -0.08528002, 0.142229, -0.08104739, -0.01835328, -0.03488622, 0.1863896, -0.0577987, 0.008513651, -0.3598242, -0.1815251, -0.3943981, -0.1446559, 0.02481749, 0.2734489, 0.04268836, 0.4127859, 0.08359332,...
Uptake and degradation of cholesterol ester-labelled rat plasma lipoproteins in purified rat hepatocytes and nonparenchymal liver cells.
1. A new method for isolation and purification of rat liver hepatocytes and nonparenchymal cells by differential centrifugation is described. 2. Cholesterol ester-labelled lipoproteins (prepared by the action of lecithin: cholesterol acyltransferase) intravenously injected were taken up by hepatocytes and nonparenchyma...
192,303
[ -0.1785122, -0.05839643, -0.2080754, 0.03210346, 0.2261023, -0.2448453, -0.2194692, 0.2904227, -0.01097825, 0.3263538, 0.2058341, -0.08920737, 0.1178843, -0.005561983, -0.445693, 0.09023284, -0.5739148, -0.05606263, -0.2228027, 0.2481172, -0.0442118, 0.2811812, -0.0049812...
[Phosphorylation of some thiamine analogs by yeast thiamine pyrophosphokinase].
A rapid efficient method of separation of the thiamine pyrophosphokinase reaction products (ATP: thiamine pyrophosphotransferase) on the column packed with DEAE-Sephadex A-25 and their subsequent identification by direct spectrophotometry is suggested. Phosphorylation of some thiamine analogs substituted at the second ...
192,330
[ -0.1546828, -0.01582876, 0.09199695, -0.2947176, 0.1568887, -0.1854727, 0.01353791, 0.2231799, 0.03283048, -0.081364, 0.1908735, 0.2103903, -0.04960499, 0.07659424, -0.9258549, -0.08953403, -0.5878199, 0.1661397, -0.04844979, 0.3156736, 0.6697091, 0.1570795, -0.2618247, ...
[Biosynthesis of cardiolipin in the rat hepatoma 27 and Jensen sarcoma].
The localization of cardiolipin biosynthesis in rat hepatoma 27 and Jensen sarcoma cells was investigated. In both tumors cardiolipin was found to be synthesized only in the mitochondria as is the case in normal rat liver. It is concluded that the occurrence of cardiolipin in the microsomes of the tumor cells may be co...
192,337
[ -0.2432313, -0.08013768, -0.3907413, -0.1205852, 0.06200929, -0.008601344, -0.5317515, 0.2809728, 0.0743859, -0.125216, 0.1451483, -0.03634402, 0.3440181, 0.07635766, -0.7568869, -0.1678569, -0.2597057, -0.09294473, -0.1228809, 0.2339849, 0.3440026, -0.1270241, 0.01976157...
[Role of specific iodothyronine-binding proteins in the process of nuclear-cytoplasmic thyroid hormone interrelationships in liver cells].
A study was made of the role played by specific iodinethyrodine-binding proteins of rat hepatocytes in the process of nucleo-cytoplasmic interrelations of the thyroid hormones under normal conditions in thyroidectomy and in experimental thyrotoxicosis. The concentration of the hormone-binding sites in the cell depended...
192,378
[ -0.01016996, -0.3760059, 0.03864193, -0.03896023, 0.02053038, -0.5117496, -0.1262047, 0.1931594, -0.1004268, 0.5194395, 0.2216251, 0.03209728, -0.05915524, -0.05671354, -0.4765012, -0.2081321, -0.370232, -0.1058827, 0.0848879, 0.1557542, 0.2026055, 0.319944, -0.1066946, ...
[Effect of cyclic nucleotides and isopropylnoradrenaline on oxygen tension and absorption].
Isopropylnoradrenaline (ISO), 3',5'-AMP and dibutyryl-3',5'-AMP decreased the oxygen tension (pO2) in the liver and the spleen and increased the body oxygen consumption (VO2). Time dynamics of these two effects was closely correlated for ISO and 3',5'-AMP. An increase of heat output was not accompanied by any significa...
192,382
[ -0.1438809, -0.3234525, -0.3620857, -0.00471284, 0.07322385, -0.1723204, -0.1064965, -0.199891, -0.1356059, 0.0780496, 0.05113905, -0.2011483, 0.1941506, 0.276287, -0.9092216, -0.2207967, -0.5027972, -0.03013563, -0.04881504, 0.3286584, 0.4076392, 0.02011371, -0.1477605, ...
[Change in the resistance of partially hepatectomized mice to transplanted tumors in the period of liver regeneration completion].
There were two inhibition periods of the growth of ascitic hepatoma 22a when its cells were transplanted intraperitoneally to partially hepatectomized A/he mice 1 to 12 days after the operation. The first inhibition took place when the transplantation was performed one day, and the second--3 to 10 days, after partial h...
192,386
[ -0.2347376, -0.3634546, -0.05697298, -0.4452978, 0.0008596365, -0.2463912, -0.1811029, -0.07811558, 0.2081824, 0.07651866, 0.1784831, 0.03916303, 0.07630494, -0.2277621, -0.8509042, -0.253002, -0.2605559, -0.04677013, -0.3093137, 0.5004074, 0.1876051, -0.1117773, -0.11820...
[Cell cultures obtained using collalytin from the pancreases of cattle fetuses].
The authors present morphological characteristics of primary monolayer cultures prepared from the pancreas of bovine fetuses. Combined treatment with trypsin and collalytine solutions (a preparation with collagenase activity) was used for dispersion of the tissue of the pancreas. Numerous epithelial cells corresponding...
192,389
[ 0.02191052, -0.3118353, -0.1180333, 0.4089332, 0.1579397, -0.3717372, -0.1940513, -0.01311552, 0.2229065, 0.2646607, -0.09417492, 0.06160121, -0.04565157, -0.2577055, 0.05186357, -0.238737, -0.3150292, 0.1245193, 0.1033622, 0.4777145, 0.3030818, 0.2242901, -0.1914247, -...
Selection of a stable clone of the MVPK-1 fetal porcine kidney cell for assays of foot-and-month disease virus.
The MVPK-1 cell line, derived from fetal porcine kidney cells, supports the replication of foot-and-mouth disease (FMD) virus. The cell line was adapted to grow in medium containing 5% bovine serum. The susceptibility of the adapted cells decreased as they aged at 37 degrees C. Various clones were isolated from the ada...
192,426
[ -0.2151132, -0.4330425, -0.1746052, -0.1326091, 0.3809261, -0.1756849, -0.1554088, 0.2876203, -0.08508767, -0.07129341, 0.2188594, 0.09476398, -0.003907854, 0.1939736, 0.01051048, -0.4941709, -0.5222687, 0.06604886, -0.03570494, 0.2929492, 0.1245134, 0.08435572, -0.249024...
Venereal factors in human cervical cancer: evidence from marital clusters.
All Caucasian women in a large Eastern city who developed pathologically confirmed cervical cancer between 1950 and 1969 are being prospectively followed in an epidemiological test of the venereal hypothesis of cervical carcinogenesis. We are attempting to identify all men who were married to these probands at any time...
192,439
[ -0.06210708, 0.1726215, -0.1752593, -0.07022814, 0.1577827, -0.2975216, -0.1763103, -0.005004769, 0.2106266, 0.1002058, 0.126677, -0.003755211, -0.0648043, -0.03853405, -0.4626234, -0.05166049, 0.03388733, 0.2910061, 0.2628866, -0.02607835, 0.3036331, 0.331686, -0.0084030...
Specific non-immunoglobulin G antibodies and cell-mediated response to herpes simplex virus antigens in women with cervical carcinoma.
Non-immunoglobulin G-neutralizing antibodies to herpes simplex virus (HSV) type 2 were assayed in sera adsorbed with Staphylococcus aureus Cowan I. They were present in 8% of women with normal cervical smear and in 20, 41, and 74% of women with atypia, dysplasia, and cervical carcinoma, respectively. Lymphocytes of the...
192,446
[ -0.01355093, -0.415794, -0.1921965, -0.07662789, -0.06587927, -0.004037965, -0.2602244, 0.005500779, 0.08691702, 0.2585132, 0.02103349, 0.1942818, -0.2086281, -0.04629659, -0.4719488, -0.2474254, -0.2850857, 0.1561354, -0.01952868, 0.2089521, 0.7138426, -0.06828978, 0.084...
Effect of tumor promoters on the activity of cyclic adenosine 3':5'-monophosphate-dependent and -independent protein kinases from mouse epidermis.
Cyclic adenosine 3'5'-monophosphate (cyclic AMP)-dependent and -independent protein kinases were detected and partially characterized in soluble extracts from mouse epidermis. Cylic AMP-dependent histone kinase activity was separated rom cyclic AMP-independent casein kinase activity by DEAE-Sephadex chromatography. The...
192,448
[ -0.01902476, -0.226827, 0.06147012, -0.2458982, 0.2480376, 0.02096534, -0.09035593, -0.1750568, 0.2711417, 0.1966554, -0.0408118, 0.02010726, 0.1496428, 0.02789525, -0.4048486, 0.2135525, -0.5125187, -0.1405363, -0.01488341, 0.08562427, 0.6804338, 0.08229538, -0.3647675, ...
[Immunofluorescence identification of cells with corticotropic and alpha-melanotropic activity in the hypophysis of the grass snake Natrix natrix L].
The use of anti ACTH (17-39) and alpha-MSH allowed us to detect by immunofluorescence in the Pituitary gland of Grass Snake the site of elaboration of ACTH and alpha-MSH. Corticotropic cells are located in the rostral part of the Pars Distalis and in the Pars intermedia. Melanotropic cells occupy the whole part of the ...
192,484
[ 0.2108257, -0.2627468, -0.1130612, 0.04155374, 0.02802188, -0.08184036, -0.4832055, 0.1141541, -0.01596301, -0.08320475, 0.1169466, 0.1409655, 0.1287686, -0.5334461, -0.4608206, -0.390565, -0.005637111, 0.5330257, 0.2342236, 0.1120713, 0.5769318, -0.04216281, -0.2087597, ...
Cholesterol determination in high-density lipoproteins separated by three different methods.
We describe a simplified method for measuring high-density lipoprotein cholesterol in serum after very-low- and low-density lipoproteins have been precipitated from the specimen with sodium phosphotungstate and Mg2+. Values so obtained correlate well with values obtained with the heparin-Mn2+ precipitation technique (r...
192,488
[ -0.0891834, 0.1728513, -0.2233988, -0.07070214, -0.1689359, -0.2011124, -0.111194, 0.2969546, -0.1263494, 0.06223475, 0.03565144, 0.2918247, 0.1137927, -0.09288748, -0.6574014, -0.3527398, -0.08037168, -0.1739984, -0.1649961, 0.4564468, 0.1964989, -0.2081033, -0.05664102,...
Collagenase activity of rat kidney with glomerulonephritis during the heterologous phase.
By means of a biological assay the collagenolytic activity of kidneys from rats with Masugi type glomerulonephritis in the heterologous phase and organs from control animals that were given normal heterologous serum was tested. Collagenolysis was found in both examples, but there wre quantitative and qualitative differ...
192,495
[ 0.03215252, 0.2455141, -0.2806787, -0.1017445, 0.2984403, -0.4172076, -0.1347134, -0.03898406, -0.07050383, -0.1968611, -0.06867064, 0.3426873, 0.03624102, 0.09753203, -0.5050206, 0.08225156, -0.255984, -0.05163283, -0.4696221, 0.1677216, 0.5333105, 0.1666624, -0.1579422,...
Low density lipoproteins and immunoglobulins in human pleural effusions.
Pleural effusions in patients with bacterial pleurisy contain low density lipoproteins (33 per cent of the blood serum LDL-concentration on average) but almost no very-low density lipoproteins (about 1 percent of the blood serum VLDL-concentration on average). Immunoglobulins are present in large amounts forming a seri...
192,497
[ -0.05677331, -0.1893512, -0.3054145, -0.1342036, -0.1188731, -0.114842, -0.321018, 0.07642768, -0.1784633, 0.1871148, 0.2779026, 0.04337769, -0.0277765, 0.2362085, -0.3617727, 0.08419565, -0.2971028, 0.03578895, 0.1375605, 0.3472014, 0.1333391, 0.09513915, 0.05060192, -...
Heterogeneity in maple syrup urine disease: aspects of cofactor requirement and complementation in cultured fibroblasts.
Fibroblast strains derived from six patients with maple syrup urine disease have been investigated for their requirements of the cofactors NAD, CoASH, Mg++ and TPP in comparison with 10 normal control strains. The reconstitution of the decarboxylase function of branched chain alpha-keto acid (BCKA) dehydrogenase comple...
192,504
[ -0.3019763, -0.04842179, -0.05569803, -0.08364498, 0.4883447, -0.3211594, -0.08237379, 0.2280409, 0.01304893, 0.0239247, 0.3662331, 0.1913113, -0.09231285, 0.4134142, -0.939607, 0.2740756, -0.3536601, 0.00278734, -0.3268393, 0.3404296, 0.470329, 0.06423944, 0.09207094, ...
Stimulatory and inhibitory effects of dimethyl sulfoxide and ethylene glycol on ATPase activity and calcium transport of sarcoplasmic membranes.
1. The effect of dimethyl sulfoxide (Me2SO) and ethylene glycol on two different preparations of the sarcoplasmic reticulum, i.e. native membranes and membranes whose phospholipids were hydrolyzed by phospholipase A, were investigated using ATP and p-nitrophenylphosphate as substrates. 2. Me2SO and ethylene glycol inhi...
192,554
[ -0.5889241, -0.005434911, -0.272057, -0.1290969, -0.02528056, -0.1158582, 0.1292772, 0.2228345, 0.01307319, 0.1685422, 0.1425031, 0.4159074, -0.01285069, 0.08789311, -0.6271565, 0.07113305, -0.3791255, -0.06677588, -0.2237537, 0.3219854, 0.3730361, 0.1950495, -0.1124256, ...
Juvenile familial hypertriglyceridemia and growth retardation. Clinical and biochemical observations in three siblings.
Familial hypertriglyceridemia or hyperlipoproteinemia type I was detected in three siblings aged 6, 11, and 14 of an otherwise normal Turkish family of 10 members. Initial values ranged from 1780 to 3750 mg/100 ml triglycerides in the milky white serum; cholesterol was normal. Lipoprotein pattern on agarose and acrylam...
192,555
[ 0.05427813, 0.03935905, -0.0586611, 0.018792, 0.286096, -0.2961692, 0.0256022, 0.06389339, -0.2888228, -0.07884573, 0.2270955, 0.164148, -0.1564321, 0.1824592, -0.5705972, 0.02042604, -0.3074196, -0.05927869, 0.0757063, -0.186819, 0.5115646, 0.07858851, 0.0441522, 0.179...
Transpyloric prolapse of polypoid gastric carcinoma.
Four patients with discrete intraluminal filling defects in the duodenal bulb secondary to transpyloric prolapse of polypoid gastric carcinoma are reported. The lesions were pedunculated in 2 cases and sessile in the remaining 2. The clinical, radiological,and pathological findings are discussed. Prolapsed gastric carc...
192,628
[ -0.3047772, -0.1216022, 0.02692037, -0.2765414, 0.1548894, -0.3172064, 0.0726888, -0.2988149, -0.06684969, 0.4686191, 0.3606287, -0.02000036, -0.5641329, -0.13776, -0.3835824, -0.0199882, -0.3610734, 0.03284178, -0.02396404, -0.1196015, 0.3460334, 0.2449356, 0.03003637, ...
Certain aspects of the use of new method of microscopy in oncology.
Electron microscopic studies on human neoplasms demonstrated that the typical cells fo individual neoplasms retain the ability of showing their specific ultrastructural differentiation. This fact provides theoretical basis for the use of electron microscopy in oncological practice for purposes of differential diagnosis...
192,640
[ -0.1903077, -0.1244226, -0.05415177, -0.1047498, -0.07538627, -0.3634897, -0.0662161, 0.1943711, 0.2695656, 0.2929876, 0.003284725, 0.009657843, 0.0805435, -0.1441446, -0.5565406, -0.3189042, -0.06375124, -0.1625385, 0.04922303, 0.1033643, 0.321524, 0.1663423, -0.2216152,...
[Polyneuropathies as a diagnostic and therapeutic task].
Despite their variety the syndromes of peripheral neuropathy are variations of just one subject. The most different lesions might be their cause. Therefore, one should not be satisfied with the diagnosis peripheral neuropathy, but should always try to clarify the etiology. Form and extension of the disturbances give es...
192,651
[ -0.0552994, -0.06241638, 0.1753121, -0.220833, -0.1002222, -0.3102132, -0.06517736, -0.05532543, 0.1594816, 0.05868077, 0.1067632, -0.1327402, 0.2242634, -0.1213181, -0.2949231, -0.1928478, -0.2121251, 0.01433734, -0.08020578, 0.3633475, 0.0373994, 0.06838335, 0.06610898,...
Mechanisms of resistant of herpesviruses: comparison of the effectiveness of different cell types in mediating antibody-dependent cell-mediated cytotoxicity.
Enriched populations of polymorphonuclear leukocytes (PMN) and macrophages obtained from the mammary gland and of granulocytes (PBG) and lymphocytes (PBL) prepared from peripheral blood of the same animal were compared for their ability to mediate antibody-dependent cell cytotoxocity against antibody-sensitized infecti...
192,672
[ 0.2279175, -0.3601645, -0.3235073, -0.4674358, -0.02328155, -0.4071155, 0.3422499, -0.2225888, -0.2701506, 0.2789738, -0.05480393, 0.000440052, 0.2321325, 0.2417563, -0.004340154, -0.155002, -0.7335101, -0.03495514, -0.1084679, 0.6561018, 0.3029851, 0.1654442, 0.01538215,...
Effect of virus infection and cycloheximide treatment on the labeling of cellular phospholipids with 32 P.
The total amount and the relative proportions of labeled phospholipids were studied in chorioallantoic membrane cells (CAM), chick embryo cells (CEC) and L cells which were either infected with Newcastle disease virus (NDV), fowl plague virus (FPV) and mouse encephalomyocarditis (EMC) virus or treated with cycloheximid...
192,694
[ -0.3211262, -0.05100834, -0.07808946, -0.1515504, 0.1604826, 0.1688588, 0.05951765, 0.1614594, 0.07537932, 0.1288886, -0.2432993, 0.1687846, 0.1638113, 0.2679605, -0.2289241, 0.0288322, -0.5218642, 0.1385312, -0.4335698, 0.5392969, -0.002699316, -0.08998153, -0.4365262, ...
Nine simultaneous primary tumors in a Boxer dog.
An aged Boxer dog had 9 distinct primary tumors: chemodectoma, osteosarcoma, bronchiolo-alveolar adenocarcinoma, interstitial cell tumor, seminoma, basal cell tumor, fibropapilloma, adrenal cortical adenoma, and pancreatic adenoma. From this report, as well as from other studies, it is clear that Boxers have special su...
192,704
[ -0.1073852, 0.1709344, 0.101376, -0.3509575, -0.4019186, -0.2220789, -0.2708614, 0.06977726, 0.1727408, 0.2059648, 0.3642774, -0.1533714, -0.1525465, -0.3468597, -0.1581504, -0.008201968, -0.1520363, 0.2549794, 0.1870077, 0.1949076, -0.06006812, -0.1243702, -0.03330836, ...
Intracellular utilization of superoxide anion by indoleamine 2,3-dioxygenase of rabbit enterocytes.
The participation of superoxide anion (O2-) in the intracellular indoleamine 2,3-dioxygenase activity was studied using the dispersed cell suspension of the rabbit small intestine. The dioxygenase activity was assayed by measuring [14C]formate released from DL-[ring-2-14C]tryptophan. The addition of diethyldiethiocarba...
192,720
[ -0.2352663, -0.2810182, -0.1889758, -0.03474345, 0.1056643, -0.2985816, 0.02161694, 0.08498766, -0.1034135, -0.205597, 0.1045393, -0.0278736, -0.08406626, 0.3245195, -0.8337299, 0.2608743, -0.4346609, 0.2480035, 0.02117898, 0.2240718, 0.1685917, 0.2065401, -0.006057416, ...
Ionic inhibition of catalytic phosphorylation of histone by bovine brain protein kinase.
The effects of various ions commonly found in protein kinase assays upon the rate of histone phosphorylation catalyzed by the highly purified bovine brain enzyme, protein kinase I, have been investigated. Sodium, potassium, and magnesium were found to inhibit histone phosphorylation by protein kinase I in a similar ma...
192,725
[ 0.1247749, 0.04270041, -0.09817041, 0.05084219, 0.1338119, 0.178514, -0.1233573, 0.2772866, 0.01601081, -0.02278808, 0.1609226, 0.3796264, 0.1469836, 0.08784391, -0.3426605, 0.1422824, -0.4331042, 0.08244497, -0.2571294, 0.0746048, 0.2504063, -0.05510484, 0.008479672, 0...
Nuclear mutations affecting mitochondrial structure and function in Chlamydomonas.
Wild type cells of the green alga Chlamydomonas reinhardtii can grow in the in the dark by taking up and respiring exogenously supplied acetate. Obligate photoautotrophic (dark dier, dk) mutants of this alga have been selected which grow at near wild type rates in the light, but rapidly die when transferred to darkness...
192,732
[ -0.02538445, 0.05328483, 0.03955471, 0.1911168, 0.06396265, -0.1700056, -0.07463365, 0.2460334, 0.3236943, -0.0445751, 0.2040582, 0.1547375, -0.09671757, 0.2695265, -0.3581461, 0.0466009, -0.5138087, 0.00863053, -0.04770484, -0.1641622, 0.2881423, 0.4086647, -0.03944574, ...
Cell cycle changes in transformed cells growing under serum-free conditions.
Polyoma transformed hamster cells (PyBHK) and SV40 transformed mouse cells (SV3T3) were transferred in culture using crystalline trypsin followed by neutralisation with soybean trypsin inhibitor. Such cells were able to proliferate freely in defined medium without any serum supplement and without any intervening period...
192,740
[ -0.4220857, -0.2647476, -0.3395112, -0.1058591, -0.1410249, -0.08029339, 0.05445812, 0.3792943, 0.4185159, 0.1312287, 0.03060061, -0.08886991, -0.33602, 0.01041848, -0.300528, -0.1160482, -0.2514411, -0.0554065, 0.0001960997, 0.5134674, 0.321244, 0.06043411, -0.4531375, ...
Leukocyte and lymphocyte cyclic AMP responses in atopic eczema.
Lymphocytes from subjects with mild and severe atopic eczema were compared with normal control subjects in regard to their cAMP (3';5'-cyclic adenosine monophosphate) responses to a variety of stimulatory agents. Individuals in the severe eczema group were shown to have a significant diminution in their unstimulated ly...
192,803
[ -0.02953195, -0.1955925, -0.2854617, -0.112062, -0.01246307, -0.2481324, -0.09001262, 0.132513, -0.1040148, -0.1002696, -0.04758439, -0.04020852, 0.02809874, 0.4246417, -0.01211997, -0.02693026, -0.3974363, 0.109884, -0.1371827, 0.2205223, 0.449836, 0.08258899, 0.1262028,...
Clinical and pathogenetic studies of Medical Lake macaque virus infections in cynomolgus monkeys (simian varicella).
The Medical Lake macaque (MLM) virus produced varicelliform eruptions in cynomolgus monkeys. Not all experimentally infected monkeys developed overt disease; viremia was found, and specific antibodies were detected. Specific lesions were found in skin, lymph nodes, and spleen. Focal inflammatory lesions were present in...
192,806
[ -0.1668991, -0.1901888, -0.2902233, -0.1229145, -0.3149729, 0.04020035, -0.470567, 0.1829813, -0.26382, -0.23015, 0.1953253, -0.00627793, 0.2641506, -0.3132201, -0.4140231, -0.02900425, -0.03397481, -0.002049193, 0.1775211, 0.2211374, 0.5361895, 0.4087287, -0.1794851, -...
Genetic control of resistance to subgroup A and subgroup C tumour viruses in Rhode Island Red fowl: evidence for linkage between the tumour virus a (tva) and tumour virus c (tvc) loci.
A study, using the Rhode Island Red (RIR) strain of fowl maintained at Houghton Poultry Research Station, was made to investigate the genetic control of cellular response to infection with viruses of subgroups A and C. Family matings within the RIR strain and test-crosses between the RIR parents and White Leghorn (WL) ...
192,840
[ 0.1411901, -0.4581164, 0.03746473, -0.5236782, 0.08863858, -0.2758492, -0.0710748, 0.1499689, -0.0191758, 0.3607675, 0.1602402, 0.3955023, -0.06362104, 0.1983014, -0.2457072, -0.6165761, -0.2227328, 0.03488792, 0.1814773, -0.1256271, -0.05486076, 0.1388619, -0.5854616, ...
Immunogenic and cell attachment sites of FMDV: further evidence for their location in a single capsid polypeptide.
Chymotrypsin cleaves only one of the four major polypeptides of foot-and-mouth disease virus (FMDV serotype O) in situ. This polypeptide (VP1, mol. wt. 29 X 10(3) was first cleaved into fragments of mol. wt. 20 and 9 X 10(3) and further cleavage could be prevented by the addition of a large excess of bovine serum album...
192,841
[ -0.1834335, -0.2088324, -0.2856549, -0.1002111, 0.2740704, -0.2292961, 0.03306382, 0.1421877, -0.02448099, 0.08617121, 0.1043103, -0.02987297, -0.010351, -0.2236946, -0.2595978, -0.2810938, -0.3330953, -0.0005993758, 0.01942488, 0.3026285, 0.2152925, 0.2109767, -0.3992782...
Comparative effects of herpes simplex virus types 1 and 2 in organotypic cultures of mouse dorsal root ganglion.
Mature organized cultures of mouse dorsal root ganglion (MDRG) were infected with herpes simplex virus, type 1 (HSV 1) and type 2 (HSV 2). Onset of infectious virus production occurred faster and reached higher levels in HSV 2-infected cultures. Neurons, supporting cells and myelin were affected in both types of infect...
192,854
[ -0.05410588, -0.2107597, -0.5158357, -0.04526365, -0.0354391, -0.2186159, 0.05534311, 0.07886546, 0.1767346, 0.1635727, -0.1341968, -0.1648787, -0.1477769, 0.3828133, -0.4225825, 0.01382506, -0.1974221, 0.2109466, -0.01055775, 0.01161563, 0.05988296, 0.1729348, 0.1312361,...
Role of dietary calcium and calcium binding protein in cadmium toxicity in rats.
Growing male rats were fed a purified diet containing 0.6% Ca (two groups) or 0.1% Ca (two groups) for 8 weeks. One 0.6% Ca group and one 0.1% Ca group received 25 ppm Cd (as CdC12) in the drinking water. Diets were fed on an equalized basis with the 0.1% Ca + Cd group determining the amount of diet fed to the other gr...
192,863
[ -0.5391049, 0.07129633, -0.1779073, -0.06582765, 0.0851496, -0.2366827, -0.3666651, 0.1969404, -0.01787213, 0.03055601, 0.08064912, 0.2979734, 0.3291054, -0.1408151, -0.7497375, 0.1244182, -0.3113466, 0.02008821, -0.07304588, 0.2984614, -0.06250189, 0.4036261, 0.05802579,...
Effect of implantation of an extra nerve on the recovery of neuromuscular transmission from botulinum toxin.
1. The common peroneal nerve was implanted into soleus in the mouse and 2 weeks later a sublethal dose of botulinum toxin injected causing a block of neuromuscular transmission at the terminals of the soleus nerve. Most muscle fibres became innervated by the common peroneal nerve. 2. Recovery of neuromuscular transmiss...
192,880
[ -0.1731753, 0.04802221, -0.2202815, -0.1833606, -0.148492, -0.161599, -0.04581569, 0.1517131, 0.004237826, 0.01466829, -0.03071687, -0.0484672, 0.2030263, -0.2255532, -0.3262556, -0.3283925, -0.2069201, 0.07313174, -0.00407299, 0.3359738, -0.07065453, 0.2269065, 0.2107528...
A solid-phase radioimmunoassay for Epstein-Barr virus-associated membrane antigen prepared from B95-8 cell culture supernatants.
Epstein-Barr virus(EBV)-associated membrane antigen (MA) was concentrated from B95-8 cell culture media by precipitation with polyethylene glycol followed by chromatography on Bio-Gel A-50m. In a RAJI cell-binding assay, MA-positive material could only be found in the void volume of the column. After ultracentrifugatio...
192,896
[ -0.2366454, -0.1635415, -0.05936116, -0.09864824, -0.02855231, 0.1041361, -0.387567, 0.3258957, 0.2521924, 0.2090329, 0.2848074, -0.008293731, 0.06059483, 0.02825332, -0.3953712, -0.09510761, -0.2494255, 0.1471209, -0.06532383, 0.3549829, 0.6761467, -0.1004263, -0.1061461...
Use of the telephone for short-term follow-up.
We have instituted a telephone appointment system (TAS) to follow patients with well-defined relatively minor problems. The patient is asked to call a special phone number at a specified date and time to obtain test results or information. A senior physician reviews each chart beforehand and indicates in lay terms, the...
192,973
[ 0.04576373, 0.02686926, -0.207966, -0.03371679, -0.006125711, 0.0008432345, 0.09492687, -0.1022909, -0.14392, -0.1138921, 0.02663966, 0.01517715, -0.01098898, 0.1125567, -0.3968626, -0.3211469, -0.2049656, 0.2012303, -0.1333973, -0.1134794, 0.02521819, -0.134087, -0.06638...
Spontaneous regression in choriocarcinoma and related gestational trophobalstic neoplasms.
Gestational trophoblastic neoplasia represents a biologic spectrum of tumors progressing from the hydatid mole, to invasive mole, and to choriocarcinoma. This progression is reflected in increasing degrees of aneuploidy in the respective lesions. Just as there is a natural tendency for the rejection of the trophoblast ...
193,022
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Transfer of the gene for thymidine kinase to thymidine kinase-deficient human cells by purified herpes simplex viral DNA.
Transformation of human cells from a thymidine kinase (ATP:thymidine 5'-phosphotransferase, EC 2.7.1.75)-negative to a thymidine kinase-positive phenotype has been achieved by using purified DNA from herpes simplex virus type 2. The specific activity of the DNA was in the range 0.5 to 2.0 transformants per microng and ...
193,108
[ -0.1129213, -0.1714854, -0.313078, -0.3705031, 0.09556971, -0.1155815, -0.1309279, 0.1273918, 0.2381738, -0.01895167, 0.4488136, -0.149726, -0.01935385, 0.4115203, -0.5985698, -0.05503545, -0.2144807, -0.08267148, -0.152299, 0.3334548, 0.5394776, 0.013689, 0.0815497, 0....
Quantitative determination of transformed cells in a mixed population by stimultaneous fluorescence analysis of cell surface and DNA an individual cells.
Cell-surface labeling with fluorescamine indicates that the fluorescence of Balb 3T3 A31 cells in considerably decreased after both viral and chemical transformation. This phenomenon, coupled with the technique of flow microfluorometry, enabled nontransformed and transformed cells to be distinguished. A second fluroesc...
193,110
[ -0.3144814, -0.2518009, -0.2952154, -0.04698453, 0.3992141, -0.2229852, -0.2321192, 0.08348732, 0.4201213, 0.2334737, -0.01243122, -0.07138934, -0.1155532, 0.09259891, -0.2422297, 0.02623637, -0.2069875, -0.07517361, -0.1466561, 0.2870354, 0.5171502, -0.1006548, -0.208202...
Relationship between serum sex hormones and glucose, insulin and lipid abnormalities in men with myocardial infarction.
Fifteen patients who had had a myocardial infarction before the age of 43 were compared with thirteen age-matched normal subjects. Twelve of the patients and three of the controls had a delayed glucose and insulin peak in the glucose and insulin areas than normal curves. When the measurements of the four patients with ...
193,114
[ -0.1509019, 0.1904039, -0.3129345, -0.4642618, 0.09167414, -0.3224973, -0.202746, 0.3641374, 0.1345248, 0.1135102, 0.07951625, 0.2213967, -0.2360904, -0.004801105, -0.3200917, -0.4537829, -0.1618527, -0.03231943, -0.006372876, 0.2766493, 0.2379052, 0.09942609, -0.0642386,...
Composition of some urinary calculi of ruminants in Western Australia.
Forty ruminant urinary calculi, selected as being essentially inorganic and mainly obtained from sheep grazing in the drier wheatbelt areas of Western Australia, were examined by optical and X-ray diffraction techniques. Four mineral types-silica (SiO2-nH2O), weddellite (CaC2O4-2H2O), calcite (CaCO3) and aragonite (CaC...
193,170
[ -0.08909447, 0.6380311, 0.08977793, 0.1071019, -0.2356655, -0.3610308, -0.1726828, 0.02573893, 0.3147013, -0.009880003, -0.05585663, 0.2565436, 0.1802782, -0.395151, -0.6508969, 0.2058932, -0.4023907, 0.6705619, 0.197894, 0.0897451, -0.04907814, 0.3592795, -0.4706697, 0...