title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The immunodepressive effect of infectious bursal agent on vaccination against Newcastle disease. | Immunodepression due to an infectious bursal agent (IBA) infection depends on the age of the birds, the time of Newcastle disease (ND) vaccination and the IBA strain used. The immunodepressive effect of IBA on ND vaccination can be avoided by vaccinating the chicks against ND at day old or by using attenuated strains o... | 193,172 | [
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[Study of foot-and-mouth disease virus inhibitors in cell cultures and experimental animals]. | Studied was the inhibiting action of some synthetic agents conditionally denoted No. 3 (benzamidazol), No. 76, and No. 78 (imidazolins) on the reproduction of the foot-and-mouth disease virus in cell cultures, newborn mice and guinea pigs. It was irrefutably demonstrated that all three agents produce an inhibiting effe... | 193,238 | [
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[Comparison of lipoprotein spectrum and lipids in maternal blood and in umbilical cord blood of newborn infant]. | Content of beta- and pre-beta-lipoprotein fractions, total cholesterol and triglycerides was distinctly lower in blood serum of infant than in maternal one. In serum of funicular blood content of free fatty acids was 2.5-fold higher than in maternal blood serum; in erythrocytes of infant content of cholesterol was foun... | 193,293 | [
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Antiviral activity of certain hetarylhydrazones in Mengo virus infected mice. | Out of a series of eleven related hetarylhydrazones four derivatives (ZIMET 124/73, ZIMET 38/74, ZIMET 44/69, and IMET 98/69), after subcutaneous administration (0.5 mmole/kg per injection), were found to possess significant antiviral activity against rapidly progressing and highly lethal Mengo virus encephalitis in mi... | 193,309 | [
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[Oncogeny of herpes simplex viruses and lupidon]. | The part of the herpes simplex virus type 2 in the development of the cervex carcinoma of women is still an open question. After the serological findings that patients with cervix carcinoma have a higher rate of antibodies against type 2 than healthy women, which were initially published with great expectation, the mol... | 193,311 | [
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Infantile chronic peripheral neuropathy with giant axons. Report of a case. | An 8-year-old boy with a slowly progressive motor neuropathy is described. The first signs appeared at the age of 3 years. Histological examination of the sural nerve showed the presence of numerous segmental axonal swellings and features of demyelination as well as remyelination. These enlargements were filled with ir... | 193,342 | [
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Viral placentitis - a case report. | A case of viral placentitis, in a 20 year-old pregnant woman suffering from chronic glomerulonephritis, was presented. In light microscopic findings of the placenta, many necrotic foci with intranuclear inclusion - bearing cells revealed in chorionic villi and by electron microscopy numerous immature and mature virus p... | 193,354 | [
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Demonstration of host antigens in the myxovirus memebrane: lysis of virus by antibody and complement. | Complement-mediated lesions developed in myxovirus membranes in the presence of antibody to host antigens. Intact virions reacted with antibody to the keratosulphate-like host antigen present in the spike layer. Spike-deprived influenza virus reacted in the same way when an antiserum to the Forssman glycolipid was used... | 193,355 | [
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H1 - and H2-receptor mediated responses to histamine on contractility and cyclic AMP of atrial and papillary muscles from guinea-pig hearts. | On guinea-pig heart we investigated whether cyclic AMP serves as a messenger for H1 - and/or H2-mediated responses to histamine. (1) On papillary muscle histamine elicited positive inotropic responses which were antagonized by burimamide but not by promethazine. The stimulation of H2-receptors was not only associated w... | 193,383 | [
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Morphological and histochemical organization of the flexor carpi radialis muscle in the cat. | Most studies concerning the structure and function of skeletal muscle have utilized the hind limb of the experimental animal. However, it has been shown that the number of behavioral tasks performed by the cat's forelimb is greater than that of the hind limb. In addition, the forelimb muscles exhibit a functional compl... | 193,389 | [
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Cyclic 3',5' -adenosine monophosphate in umbilical cord and maternal plasma before and after the onset of parturition. | Significant arteriovenous differences in cord cyclic 3',5'-adenosine monophosphate (cAMP) levels and between the maternal plasma (MP) and each cord vessel (mean umbilical artery [UA] greater than umbilical vein [UV] greater than MP) was observed. cAMP levels were significantly higher in the umbilical cord vessels and m... | 193,401 | [
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Dependence of tonin activity in rat submaxillary gland on growth hormone and testosterone. | Tonin, an enzyme present in rat submaxillary gland, converts angiotensin I to angiotensin II and is able to form angiotensin II directly from renin substrates. This enzyme was previously shown to be different from renin, tissue isorenins, and angiotensin I converting enzyme. The specific activity of tonin in rat submax... | 193,408 | [
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Susceptibility of Clostridium perfringens isolated from human infections to twenty antibiotics. | The proper choice of antibiotic for Clostridium perfringens infections in patients allergic to penicillin is not clear; the usual recommendations and recent in vitro studies disagree. We tested the susceptibility of 57 strains of C. perfringens to eight penicillins, seven cephalosporins, two tetracyclines, clindamycin,... | 193,441 | [
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Myogenic foam cells in explants of fatty dots and streaks from rabbit aorta. Morphological studies. | Present studies indicate that in explants of early atherosclerotic lesions removed from aortae of young rabbits on a 1% hypercholesterolemic diet for four and seven weeks respectively, myogenic foam cells (MCF's) were capable of emigrating into the culture medium and maintained their ability to produce microfibrils, el... | 193,521 | [
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Physical properties of the dimyristoylphosphatidylcholine vesicle and of complexes formed by its interaction with apolipoprotein C-III. | The structure of a single bilayer vesicle of dimyristoylphosphatidylcholine has been characterized by sedimentation, densimetry, and light-scattering measurements. The molecular weight, partial specific volume, Stokes radius, and degree by hydration were found to be 2.68 X 10(6), 0.972 cm3/g, 125 A, and 0.86 g/g, respe... | 193,554 | [
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An essential arginine residue in the ATP-binding centre of (Na+ + K+)-ATPase. | 1. Incubation of purified (Na+ + K+)-ATPase (ATP phosphohydrolase EC 3.6.1.3) from rabbit kidney outer medulla with butanedione in borate buffer leads to reversible inactivation of the (Na+ + K+)-ATPase activity. 2. The reaction shows second-outer kinetics, suggesting that modification of a single amino acid residue is... | 193,570 | [
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[Extraction of deuterated compounds from Chlorella sp. K. grown in D20]. | A comparison of the three known methods made it possible to work out methods of complex extraction of deutero amino acids, deutero sugars and deutero vitamins from algae Chlorella sp. K., grown autotrophically in heavy water. An analysis of the isotopic composition of deutero amino acids by PMR indicates that treatment... | 193,575 | [
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[2 types of reduction of P700+ reaction centers in the leaves of green plants]. | It is shown that in the leaves of Hibiscous sp. the ESR signal I rises under weak far red light after its partial inhibition with a short white flash is slower than after adaptation to 710 nm light and short dark exposition. It is suggested that this divergence in the ESR kinetics is due to the fact that only part of r... | 193,580 | [
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[Formation of cyclic adenosine-3',5'-monophosphate in phagocytosis]. | The content of cAMP in the phagocytizing macrophages increased, especially in the phagocytosis of live microbes. cAMP formed in phagocytosis was determined in the incubation medium, whereas in the cells its content remained practically unchanged. In the administration of E. coli 055 to the germ-free guinea pigs the con... | 193,592 | [
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[Changes in the kinin system components and structure of the myocardium under the influence of antikinin preparations in allergic myocarditis in rabbits]. | Experimental allergic myocarditis was induced in rabbits; a study was made of the effect on the kininogen content and on the activity of kininase in the myocardium, and on its morphological structure produced by anginine, contrical, aspirin, indometacine and epsilon-aminocapronic acid. The former two preparations were ... | 193,594 | [
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[Intramammary spread of breast cancer]. | At the conclusion of this study based on a careful histological analysis of 454 mastectomy specimens carried out at the Institut Gustave-Roussy between 1966 and 1971 it appears that 39 per cent of tumours which are neither central nor deep to the nipple have microscopic foci outside the main focus of tumour of which 24... | 193,599 | [
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Demonstration of heavy and light density populations of Aleutian disease virus. | A highly purified and concentrated suspension of aleutian disease virus was prepared from large quantities of early infected mink tissues using repeated fluorocarbon extraction procedures. Equilibrium centrifugation of the aleutian disease virus preparation in a cesium chloride gradient yielded three distinct bands at ... | 193,625 | [
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Presence of ribonucleotide sequences complementary to Rous sarcoma virus (RSV) RNA in chicken cells infected with RSV. | RNA--RNA molecular hybridization between [125I] RNA from Rous sarcoma virus virions and RNAs isolated from various subcellular fractions, i.e. nuclei, mitochondria, free and membrane-bound polyribosomes, from tumors induced by RSV in chickens resulted in the formation of RNAase-resistant hybrids only with the RNA of mi... | 193,629 | [
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Levels of mammary tumor virus in hormone-dependent and -independent mouse mammary tumor cells. | Levels of mammary tumor virus particles (types A and B) and levels of the virus antigen were assayed in hormone-dependent and -independent mammary tumors of GR mice. Various transplant generations of seven separate tumor lines were investigated. The results indicated that the tumors consisted of different cell clones, ... | 193,632 | [
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Plasma triglyceride secretion and metabolism in chronic renal failure. | Endogenous very low density lipoprotein triglyceride (VLDL-TG) production rate has been studied in 13 patients with chronic renal failure who were not on dialysis treatment. In these patients the VLDL-TG plasma concentration was significanlty raised when compared with the control group; the fractional turnover rate was... | 193,657 | [
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The combined effect of growth hormone and methandrostenolone on the linear growth of patients with multiple pituitary hormone deficiencies. | Six patients with multiple pituitary hormone deficiencies (MPHD) were initially treated with separate courses of methandrostenolone and growth hormone and later with the two drugs combined. During the basal period the mean growth velocity was 2.8 cm/year. Methandrostenolone alone, 0.02-0.05 mg/kg/day given to four of t... | 193,658 | [
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Perifused adipose cells, quantitation and kinetics of lipolysis. | The perifused fat cell system is a system with which lipolytic activity can be monitored on a minute-to-minute basis. Thus, the rate at which lipolysis changes following the addition and removal of hormones can be followed. Catecholamines and other lipolytic agents produced a time-dependent increase in lipolysis follow... | 193,737 | [
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... |
A double-blind comparative study of Otoseptil Ear Drops and Otosporin Ear Drops in otitis externa. | A double-blind comparative study of Otoseptil Ear Drops and Otosporin Ear Drops in otitis externa in fifty-eight patients revealed them both to be equally effective in a series with very few fungal infections. In view of the normally high proportion of infections including fungi, there are obvious advantages in using O... | 193,743 | [
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0.078047... |
Statistical evaluation of polygraphic investigations of pentoxifylline. | Changes in the electro-encephalogram, and in the electro-oculogram electromyogram, ECG, blood supply, blood pressure, electrical skin activity and neurological/psychiatric findings, were investigated in 100 patients given single administrations of 200 mg of pentoxifylline (BL 191). It is concluded from the changes in t... | 193,745 | [
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Direct serological assay for the heat-labile enterotoxin of Escherichia coli, using passive immune hemolysis. | Sheep erythrocytes sensitized with the heat-labile enterotoxin (LT) of Escherichia coli exhibited passive immune hemolysis (PIH) when exposed to specific antitoxin and complement. Thus, PIH serves as the basis for an in vitro serological assay for LT that is sufficiently specific and sensitive to differentiate LT-posi... | 193,793 | [
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Hepatography and liver lymphography by retrograde biliary ethiodol infusion: an experimental study in the dog. | Ethiodol in dosages of 0.5-3 ml/kg was retrogradely infused with hydrostatic pressure of 50--100 cm water into the biliary system of nine cholecystectomized dogs equipped with a Thomas cannula in the second portion of the duodenum, allowing cannulation of the common bile duct with a Foley catheter under direct vision. ... | 193,804 | [
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... |
In vivo aminoacylation of transfer ribonucleic acid in Bacillus subtilis and evidence for differential utilization of lysine-isoaccepting transfer ribonucleic acid species. | The presence or absence of certain amino acids has different effects on the ability of Bacillus subtilis to sporulate, and the intracellular pool size of amino acids has been reported to vary during sporulation. The idea that these variations might exert a regulatory effect through aminoacylation of transfer ribonuclei... | 193,829 | [
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Interaction of canine and swine lipoproteins with the low density lipoprotein receptor of fibroblasts as correlated with heparin/manganese precipitability. | Canine HDL1 and canine and swine HDLc were fractionated into several lipoprotein subpopulations by heparin/manganese precipitation. The ability of the various subfractions of HDL1 or HDLc to compete with 125I-labeled low density lipoproteins (LDL) for binding and degradation by human fibroblasts was compared. The HDL1 ... | 193,851 | [
0.07731551,
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Fatty acid enhancement of human serum albumin binding properties. A spin label study. | The introduction of a new spin-labeled anionic ligand, 1-gamma-aminobutyrate-5-N-(1-oxyl-2,2,6,6-tetramethyl-4-aminopiperidinyl)-2,4-dinitrobenzene, is reported. Under the experimental conditions, the first molar equivalent of this ligand is 93% bound to human serum albumin. With the addition of palmitate, the free spi... | 193,852 | [
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Shock and the kidney: pathophysiology and pharmacological support. | This article reviews current knowledge as to the physiological mechanisms that control renal vascular resistence. The contribution of both extrinsic and intrinsic neuro-humoral regulation of both blood flow and glomerular filtration rate are described. The changes that occur both to the renal blood flow and glomerular ... | 193,878 | [
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Side effects of immersion-type cleansers on the metal components of dentures. | Three metals were immersed in eight denture cleansing solutions for a period of 240 hours to determine the relative side effects of these cleansers upon various metal components of complete and removable partial dentures. Conclusions drawn from this study are: 1. Commercial bleaches and unbuffered hypochlorite solution... | 194,029 | [
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0.008138647... |
Growth curve of an experimental solid tumor following radiotherapy. | Because it has long been recognized that the growth of most untreated tumors is well described by Gompertzian or exponential growth curves but that the growth of treated tumors has never been well characterized mathematically, we developed and applied an equation that, while not dependent on restrictive assumptions or ... | 194,044 | [
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0.04251682,
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Bioactivity of C3H and RIII mammary tumor viruses in virgin female BALB/c mice. | The bioactivities of C3H and RIII mammary tumor virus (MuMTV) in virgin female BALB/c mice differed. The average number of mammary hyperplastic alveolar nodules per mouse after noduligenic tests was 20.1 in BALB/cfC3H and 10.7 in BALB/cfRIII females. Spontaneous mammary tumor incidence after 20 months of observation wa... | 194,047 | [
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... |
Expression of tumor-specific transplantation antigen in cell lines transformed by wild-type of tsA mutant simian virus 40. | The simian virus 40-induced tumor-specific surface antigen(s) (TSSA) and tumor-specific transplantation antigen(s) (TSTA)were detected in cells transformed by wild-type or temperature-sensitive mutant simian virus 40 by an antibody-mediated cytolytic assay for TSSA and an immunization test for TSTA. Cells transformed b... | 194,055 | [
0.094172,
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Spatial relationships of the proteins of vesicular stomatitis virus: induction of reversible oligomers by cleavable protein cross-linkers and oxidation. | To delineate the proximity and spatial arrangement of the major structural proteins of intact vesicular stomatitis (VS) virions, protein complexes formed by oxidation or by bivalent cross-linkers were analyzed by two-dimensional electrophoresis on polyacrylamide slab gels. H2O2 oxidation of VS virions produced an N-pol... | 194,063 | [
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0.09275942,
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0.08464249,
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Comparative studies on the '5'-cap' and in vitro translational activity of cytoplasmic and nuclear poly A(+) RNA1. | The translational activities of cytoplasmic poly A(+)RNA of normal rat liver and Novikoff hepatoma cells in the wheat germ cell free system were found to be approximately 15-20 times greater than tose of the corresponding nuclear poly A(+) RNA. The translationsl activities were 85 and 62 pmoles 3H-leucine incorporated/... | 194,141 | [
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0.2695124,
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Asbestos and glass fibres in bacterial mutation tests. | Asbestos fibres are carcinogenic in man and experimental animals but fine glass fibres are known, at present, only to be carcinogenic in experimental animals. Asbestos and glass fibres have been studied in mutation tests using auxotrophic strains of Escherichia coli and Salmonella typhimurium. The mutagenic activities ... | 194,149 | [
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The cell-growth inhibitory effect of interferon. Studies of a resistant cell-subline. | Studies performed in the CSV subline of mouse L-cells suggest that activated endogenous and/or exogenous viral infection might be the factor that modifies the cell surface and, in consequence, the sensitivity of the cell to the cell-growth inhibitory action of interferon. In contrast with the parental L-cells, the CSV ... | 194,167 | [
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... |
The effect of crocetin on skin papillomas and Rous sarcoma. | A carotenoid compound, crocetin, was used in two different types of tests involving animal tumors. These tests showed that crocetin both decreased the numbers of tumors as well as delaying onset. | 194,195 | [
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In vitro synthesis of messenger RNA by a defective interfering particle of vesicular stomatitis virus. | A defective interfering particle derived from the heat-resistant strain of vesicular stomatitis virus was analyzed for the presence of virion-associated RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6) activtiy. The RNA synthesizing capacity of the defective particles in vitro was similar ... | 194,241 | [
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The association of Wilms' tumor with second primary malignancies. | Medulloblastoma occurs uncommonly in the neonatal period. Metastatic Wilm's tumor in a newborn is extremely rare. The coincidence of these two neoplasms in one infant, and an equally uncommon combination of Wilms' tumor and a cerebellar medulloephithelioma in another child prompted this report. The authors speculate on... | 194,294 | [
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0.003004403,
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[Pancreatic island cell tumors and their syndromes. I. Insulinomas, organic hypertinsulinism]. | Based on a retrospective investigation of 61 surgical and autopsy specimens, the histopathologic features and clinical manifestations of islet cell tumors are described. In 33 cases reviewed in the first part of this study there existed indications of primary hyperinsulinism (HI) which was generally verified through fa... | 194,305 | [
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[The problem of surgical therapy of malignant kidney tumors]. | Critical examination of the results of surgical treatment and new surgical techniques have produced changes in the operative treatment of hypernephroid kidney cancer and nephroblastoma. The limits to operative treatment are, first, the local extension and infiltration of the tumor and, second, the grade and degree of m... | 194,306 | [
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0.02144461,
-0.1983595... |
[Inappropriate secretion of antidiuretic hormone: true and false Schwartz-Bartter syndrome. Apropos of 2 cases]. | The authors report two cases and consider the various physiopathological mechanisms of inappropriate hypersecretion of antidiuretic hormone. An exploration including clearance of free water and, in some cases, estimation of ADH before and after a water load, then before and after administration of ethyl alcohol, permit... | 194,321 | [
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0.09812542,
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[Polyradiculoneuritis in visceral cancer. Review of the literature. Apropos of 2 cases]. | One should distinguish two types of polyradiculoneuritis during visceral carcinoma. Metastic polyneuritis and paraneoplastic polyneuritis. They fulfil distinct anatomical criteria and their pathogenesis is different. Both, however, have clinical analogies and a similar course. The survival time in both types is usually... | 194,334 | [
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0.160556,
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... |
[Mechanism of calcium ion transport in brain microsome fractions]. | The influence of Ca2+ in rising concentrations on the ATP-dependent Ca2+-binding system of the brain microsome fraction, the inhibitory effect of SH-reagents on it and the protective effect of ATP correlate with the properties of the Mg2+-dependent Ca2+-activated ATPase of this fraction. Such properties of the system a... | 194,379 | [
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0.5064557,
0.02676887,
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0.0606... |
Mitotic histiocytes and intranuclear Langerhans cell granules in histiocytosis X. | Several mitotic histiocytes containing Langerhans cell granules were found in the lymph nodes of Letterer-Siwe disease. Some histiocytes of Hand-Schüller-Christian disease contained Langerhans cell granules within the nuclei. These Langerhans cell granules were not in 'nuclear pseudo-inclusions,' but were freely scatte... | 194,391 | [
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0.2316054,
0.3466794,
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[Enzymatic activity of glucose-6-phosphate metabolism in the liver during the administration of a hepatic carcinogen]. | In liver tissue of mice, administered with diethyl nitrosamine (2.5 mg/kg of body weight) within 2-8 months, activities of hexokinase and glucoso-6-phosphate dehydrogenase were increased and the activity of glucose-6-phosphatase was decreased . Termination of the administration of diethyl nitrosamine, which was carried... | 194,415 | [
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0.5665411,
0.00556377,
0.1619577,
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Adaptation of neuromuscular junction to transmission of impulses after inactivation of acetylcholinesterase. | Adaptation of neuromuscular junction to transmission of impulses after inactivation of acetylcholinesterase. Acta Physiol. Pol., 1977, 28 (1): 23-30. Isolated preparation of rat diaphragm with phrenic nerve was incubated in paraoxon solutions which caused complete inactivation of acetylcholinesterase. This inactivation... | 194,461 | [
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0.1316331,
0.3518101,
0.03328... |
Myospherulosis. An electron-microscopic study of a human case. | An electronmicroscopic study of a human case of myospherulosis, which involved the nose and maxillary sinus, is reported. Large parent bodies limited by a thick electron-dense wall, enclosing variable numbers of spherules, were seen in cystic tissue spaces or adjacent connective tissue. Free spherules and shrunken dege... | 194,473 | [
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0.2184022,
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0.254449,
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0.06838365,
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0.2399178,
-0.3357912,
-0.04761815,
0.1236514,
-0.09484917,
0.3478233,
0.106442,
0.106547... |
Prevention or modification of varicella using zoster immune plasma. | Zoster immune plasma (ZIP) was given to 31 susceptible immunocompromised children one to seven days (median, two days) following household, playmate, or hospital exposures to varicella. The average amount of ZIP transfused was 7 ml/kg. Twenty-one children did not develop varicella or persistent antibodies to varicella-... | 194,476 | [
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0.112... |
Prognosis and treatment in minimal breast cancer. | Of 176 patients with minimal breast cancer, 138 had intraductal carcinoma in situ, 21 minimally invasive carcinoma, and 17 lobular carcinoma in situ. Various modalities of treatment were used including radical, modified radical, and simple mastectomy with and without radiation therapy. Long-term postoperative follow-up... | 194,494 | [
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Evidence for the involvement of microtubules in wound contraction. | Many theories have been proposed for the mechanism of wound contraction, that phenomenon of wound closure in which the skin surrounding the tissue defect is drawn into the open wound. When agents that inhibit microtubular function, such as vinblastine and colchicine, were topically applied to actively contracting wound... | 194,495 | [
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0.04262303,
-0.09716059,... |
Neuromuscular block by antibiotics: polymyxin B. | Characteristics of neuromuscular block produced by polymyxin B (PXB) were examined in 12 anesthetized cats, using sciatic nervetibialis anticus muscle preparations. The ED50 was 6.7 (+/- 1.4, SD) PXB base/kg body weight. The ED95 was 10.8 (+/- 2.4) mg/kg. Spontaneous recovery from 25 percent of control to 75 percent of... | 194,505 | [
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0.1995274,
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0.1757515,
0.0867919... |
Mannitol oxidation in two Micromonospora isolates and in representative species of other actinomycetes. | Mannitol kinase and mannitol-1-phosphate dehydrogenase activities were detected in two Micromonospora isolates. The presence of these enzyme activities indicates that mannitol is catabolized first to mannitol-1-phosphate and then to fructose-6-phosphate. Mannitol-oxidizing enzymes were also surveyed in representative s... | 194,534 | [
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0.1381564,
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Malignant disease in childhood: the problems in general practice. | The role of the family doctor with regard to malignant disease in childhood, can be summarized as follows: To act appropriately so that early diagnosis, which to an important degree determines the prognosis, is not delayed by a justifiably low index of suspicion. To assist the family, including the siblings, to cope wi... | 194,559 | [
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0.3810109,
0.2095216,
0.5235976,
0.04059562,
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-... |
Congenital cerebellar hypoplasia in jersey calves. | Congenital cerebellar hypoplasia and hydrocephalus is reported in 8 Jersey calves. The possible relationship between this entity and BVDMD virus is discussed. | 194,564 | [
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0.2650387,
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0.1045447,
... |
Pacheco's parrot disease of psittacine birds. | Pacheco's parrot disease was identified as the cause of death of 3 psittacine birds at an aviary. Confirming a previous report, a herpesvirus was found to be the etiologic agent. The virus induced mortality in embryonated chicken eggs and budgerigars. The virus was characterized by electron microscopy, filtration exper... | 194,568 | [
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Possible mechanisms involved in the stereotyped behavior elicited by amphetamine. | In a variety of animals, amphetamine administration produces an increase in locomotor behavior and an induction of repetitive, stereotyped behaviors. There is now considerable evidence to suggest that the induction of stereotyped behaviors is accomplished, in part, by alterations in catecholaminergic transmission in th... | 194,632 | [
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0.1183348,
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0.1062398,
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0.1900325... |
Parallel tubular arrays in severe combined immunodeficiency disease: an ultrastructural study of peripheral blood lymphocytes. | The ultrastructure of the lymphocytes from three children with severe combined immunodeficiency disease (SCID) is described. Parallel tubular arrays (PTA) were found in a large percentage of circulating lymphocytes (53%, 41%, and 13%) in three SCID patients when compared to age-matched controls. The size of these inclu... | 194,640 | [
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0.1545034,
0.3085034,
0.1877585,
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Myeloperoxidase--H2O2--halide system: cytotoxic effect on human blood leukocytes. | Myeloperoxidase, H2O2, and a halide form a potent antimicrobial and cytotoxic system of the polymorphonuclear leukocyte. A cytotoxic effect of this system on human blood leukocytes is demonstrated, employing 51Cr release and dye exclusion assays. Cytotoxicity is dependent on enzymatically active myeloperoxidase, H2O2, ... | 194,641 | [
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0.1361159,
0.... |
Autoradiographic localization of opiate receptors in rat brain. II. The brain stem. | The distribution of opiate receptors, determined by the autoradiographic localization of stereospecific [3H]diprenorphine binding sites, was studied in the brain stem. Areas showing very dense or dense localizations of receptors included the parabrachial nuclei, the superior colliculus, the ventral median raphe nucleus... | 194,658 | [
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... |
The structure of cellulose-producing bacteria, Acetobacter xylinum and Acetobacter acetigenus. | The structure of the pellicles and cells of the cellulose-producing bacteria, Acetobacter xylinum and Acetobacter acetigenus, was studied by transmission electron microscopy of thin sections and freeze-etch replicas of glucose-stimulated cell suspensions, quiescent cell suspensions, and discrete pellicles. These bacter... | 194,664 | [
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0.04875696,
0.003242991,
... |
Congenital hepatic fibrosis, liver cell carcinoma and adult polycystic kidneys. | In reviewing the literature, we found no liver cell carcinoma (LCC) or well-documented adult polycystic kidneys (APK) associated with congenital hepatic fibrosis (CHF). We report a 69-year-old man with CHF, LCC, APK, duplication cyst of distal portion of stomach, two calcified splenic artery aneurysms, myocardial fibro... | 194,672 | [
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0.1... |
Differences in mouse mammary tumor viruses. Relationship to early and late occurring mammary tumors. | The murine model has been used extensively to study the various factors involved in the etiology of mammary carcinoma. Inbred mouse strains have been classically categorized into (i) high incidence stains with tumors occurring relatively early in the life of the animal, or (ii) low or moderate incidence strains with tu... | 194,675 | [
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0.4954745,
0.0572584,
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0.204... |
Similarities of two hepatitis A virus strains. | In outbreaks of type A hepatitis in Los Angeles, USA, and Rosario, Argentina, virus particles were isolated from faeces. The geographically diverse strains were identical in appearance and serological reactivity. They differed only in buoyant density, but other workers have also obtained inconsistent results in estimat... | 194,718 | [
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... |
Endodermal sinus tumor of the mediastinum. Ultrastructural study. | This is the eighth case report of an endodermal sinus tumor of the mediastinum (first case studied by electron microscopy). The ultrastructure of the tumor was found to mimic that of the normal yolk sac and was also similar to that of three previously reported cases of endodermal sinus tumor of the ovary, thus confirmi... | 194,757 | [
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0.1891326,
0.2248188,
0.0536704... |
A radioreceptor assay for insulin: direct measurement of dog pancreatic vein serum insulin. | A simple radioreceptor assay for insulin rat liver membranes as receptor sites, with sufficient specificity precision, and sensitivity to detect 10 ng or 276 muU/ml of serum insulin, has been developed. In the presence of standard porcine insulin at the concentration of 1.0 ng/tube, approximately 8% of 125I-porcine ins... | 194,769 | [
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0.152271,
... |
Mechanisms and sites of action of newer angiotensin agonists and antagonists in terms of activity and receptor. | From the myotropic and vasopressor activities of the numerous analogs of angiotensin II, it has been determined that the phenyl group of position 8 possesses the information for biologic response while the aromatic side groups in positions 4 and 6, the guanido group in position 2 and the C-terminal carboxyl are involve... | 194,800 | [
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0.1956856,
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0.03447328,
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-0.29... |
In-vitro observations on isolated adipose tissue cells from hyperobese subjects. | Isolated adipose tissue cells were prepared from subcutaneous samples obtained from nine morbidly obese subjects weighing from 187 to 306% of ideal body weight. The responsiveness of these adipocytes to a number of test substances was determined by measuring cellular cyclic AMP concentration at one-half hour and glycer... | 194,809 | [
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0.1803113,
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[The Landry-Guillain-Barré-Strohl-syndrome. Prognosis in adults (author's transl)]. | The clinical aspect of acute polyradiculitis (Landry-Guillain-Barré-Strohl syndrome) of 85 patients is resumed. 52 of these 85 patients were seen after an average of 5, 1 years, 8 were dead at the time of control and 25 could not be traced. Two patients died during the acute phase of polyradiculitis corresponding to a ... | 194,821 | [
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0.2414427,
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0.1169422,
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Specific immune lysis of paramyxovirus-infected cells by H-2-compatible thymus-derived lymphocytes. | Mice exposed to paramyxovirus (Sendai) generate specifically sensitized thymus-derived lymphocytes (T cells) which, in an in vitro 51Cr release assay, interact only with virus-infected target cells sharing strong transplantation antigens. Reciprocal exclusion of cytotoxic T-cell activity is found for Sendai virus, lymp... | 194,830 | [
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Protection against herpes simplex virus infection in mice by Corynebacterium parvum. | Corynebacterium parvum administered in mice prior to herpes simplex virus (HSV) infection significantly protected them against lethal encephalitis. This was seen both with a mouse strain highly susceptible to HSV and with one relatively resistant to HSV. Mice immunosuppressed by cyclophosphamide and showing an increase... | 194,841 | [
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0.479386,
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0.1455082,
0.2041843,
-... |
E.s.r. of spin-trapped radicals in aqueous solutions of amino acids. Reactions of the hydroxyl radical. | The radicals produced by reactions of hydroxyl radicals with amino acids in aqueous solutions have been investigated. Hydroxyl radicals were formed by U.V.-photolysis of hydrogen peroxide and the short-lived amino acid radicals were spin-trapped by tert-nitrosobutane and identified by electron spin resonance spectrosco... | 194,854 | [
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0.3200123,
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... |
Transforming activity and antigenicity of an Epstein-Barr-like virus from lymphoblastoid cell lines of baboons with lymphoid disease. | Two lymphoblastoid cell lines were established from baboons with lymphoid disease. Cells of these lines were positive for complement and Fc receptors but lacked sheep cell receptors, theraby indicating B-cell origin. The cells contained antigens which cross-reacted with Epstein-Barr virus (EBV), viral capsid antigen (V... | 194,867 | [
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... |
Effects of picric acid-formaldehyde fixation on the LH(HCG) receptors' binding activity in the rat testis. A histochemichal model for qualitative and quantitative studies. | PAF (picric acid-formaldehyde) fixation of rat testis for a short time at 0-4 degrees C was found to give satisfactory histological results and to preserve most of the specific binding activity of LH(HCG) receptors. Investigations of the characteristics of the hormone-receptor reaction after mild PAF fixation indicated... | 194,874 | [
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On the role of the tubulin nonexchangeable GTP site in bovine neurotubule assembly. | A procedure for radiolabeling the terminal phosphoryl group of the tubulin nonexchangeable GTP site using bacterial acetate kinase and acetyl-32P is described. Warming such samples to 37 degrees results in microtubule assembly and hydrolysis of the nonexchangeable site GTP in a parallel fashion. Removal of the microtu... | 194,881 | [
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-0.07789429,
-0.034... |
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP. | In the preceding paper (Sheetz, M. and S.J. Singer. 1977. J Cell Biol. 73:638-646) it was shown that erythrocyte ghosts undergo pronounced shape changes in the presence of mg-ATP. The biochemical effects of the action of ATP are herein examined. The biochemical effects of the action of ATP are herein examined. Phosphor... | 194,904 | [
-0.2786197,
0.07587335,
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0.2389588,
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0.3394346,
0.3261168,
0.1525815,
0.220542,
0.2614512,
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0.2018849,
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0.3955482,
0.6603331,
0.1864967,
-0.1915256,
-0.20... |
Hormonal control of adrenocortical cell proliferation. Desensitization to ACTH and interaction between ACTH and fibroblast growth factor in bovine adrenocortical cell cultures. | A primary bovine adrenocortical cell culture system responsive to physiological concentrations of ACTH has been established. When added to cultures, ACTH inhibited DNA synthesis and cell division over the same concentration range required for stimulation of fluorogenic steroid production (0.01-10 nM). With chronic expo... | 194,925 | [
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0.1100124,
0.06740199,
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0.4544882,
0.3714249,
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... |
Expression of AKR murine leukemia virus gp71-like and BALB(X) gp-71-like antigens in normal mouse tissues in the absence of overt virus expression. | By competition radioimmune assays with antisera against AKR murine leukemia virus (MuLV) gp 71 or antisera against xenotropic virus, and iodinated AKR MuLV gp71 or BALB(X) gp71, antigens serologically indistinguishable from the viral antigens can be detected in tissues of normal mice in the absence of overt virus expre... | 195,002 | [
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0.2026584,
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0... |
Inking in Aplysia californica. III. Two different synaptic conductance mechanisms for triggering central program for inking. | 1. In the previous two papers we described the motor elements which mediate all-or-none inking behavior in Aplysia (4) and the contribution of specific membrane properties of the ink-gland motor cells to the central program for inking (5). In the present paper we show that the central program for inking (a characterist... | 195,019 | [
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0.1743934,
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0.241... |
Stannous-ion quantitation in pyrophosphate and polyphosphate radiopharmaceutical kits using differential pulse polarography. | Stannous salts are used as reducing agents in many radiopharmaceutical kits. Differential pulse polarography, with 1 M sulfuric acid as the supporting electrolyte, is a relatively simple and effective technique for stannous quantitation and can be used in the quality assurance testing of pyrophosphate and polyphosphate... | 195,034 | [
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0.2131112,
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0.0... |
Extraocular muscle surgery in the presence of complete paralysis of the fifth, sixth and seventh cranial nerves. | A nine-year-old boy developed paralytic left esotropia secondary to an intracranial lesion. He also exhibited total loss of function of the left fifth and seventh cranial nerves. Extraocular muscle surgery in this situation was felt to be dangerous to the operated eye. The degree of risk however could not be determined... | 195,033 | [
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0.1649019,
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0.05460046,
0.08792036,
0.09423038,
... |
Mechanism of cardiovascular effects of clonidine in conscious and anesthetized rabbits. | The actions of intravenous clonidine [2-(2,6 dichlorophenylamino)-2-imidazoline hydrochloride] on blood pressure and heart rate were examined in conscious rabbits. Complete transection of thecervical spinal cord increased the intensity and duration of the hypertensive effect of 30 microgram/kg of clonidine and complete... | 195,037 | [
0.01898832,
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0.0866677,
0.2682221,
0.1444414,
0... |
Alteration of the intracellular energetic and ionic conditions by mengovirus infection of Ehrlich ascites tumor cells and its influence on protein synthesis in the midphase of infection. | Mengovirus infection of Ehrlich ascites tumor cells caused a change of the intracellular ATP concentration. It increased by 35% within the first 3 h postinfection and then declined to zero within the next 5 h. The decrease in the ATP concentration was due, at least in part, to leakage of ATP into the medium, where it c... | 195,079 | [
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0.03046939,
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0.6827477,
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0.2723... |
Formation of reticuloendotheliosis virus pseudotypes of Rous sarcoma virus. | Superinfection of chicken embryo fibroblasts transformed by the defective Bryan strain of Rous sarcoma virus (BH-RSV) with two different reticuloendotheliosis viruses (REVs), REV strain T (REV-T) or spleen necrosis virus (SNV), resulted in the production of infectious sarcoma virus pseudotypes. These pseudotypes were n... | 195,082 | [
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0.1883967,
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0.2468944,
0.268354,
0.08593375,
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0.03560728,
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0.1591906,
0.2586681,
0.1012086,
0.3613335,
-0.2754559,
... |
In vitro translation of Harvey murine sarcoma virus RNA. | The viral RNA of the Harvey strain of murine sarcoma virus (Ha-SV), which does not encode for any known viral structural polypeptides, has been translated in a nuclease-digested, cell-free system. The major protein product of the in vitro translation reaction has a molecular weight of 21,000 and is initiated faithfully... | 195,086 | [
-0.202028,
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-0.5168451,
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0.2909487,
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0.2037351,
0.372313,
0.07733762,
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0.1040567,
0.03559536,
0.3420468,
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0.1215262,
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0.1292956,
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0.0598091,
0.2799962,
0.3650212,
-0.2900105,
-0.4168358,
0... |
Cell-free synthesis of herpes simplex virus proteins. | Polyribosomes isolated from herpes simplex virus type I (HSV-1)-infected cells have been used to program a eucaryotic cell-free translation system. At least 10 HSV-specific polypeptides, with apparent molecular weights of 25,000 to 160,000, are synthesized by wild-type HSV-infected polyribosomes. Polyribosomes prepared... | 195,089 | [
-0.09054843,
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0.2156076,
0.0522016,
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0.04954754,
0.2218775,
0.1394975,
0.006623438,
0.2214249,
0.05492698,
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-0.2157142,
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0.1679655,
0.04762238,
-0.1342991,... |
Episomal viral DNA in a Herpesvirus saimiri-transformed lymphoid cell line. | The lymphoid cell line #1670 has been derived from the infiltrated spleen of a tumor-bearing marmoset monkey infected with Herpesvirus saimiri. The cells contain both types of H. saimiri DNA, unique light (L-) DNA (36% cytosine plus guanine) and repetitive heavy (H-) DNA (71% cytosine plus guanine), without producing i... | 195,090 | [
0.005384318,
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-0.1559523,
-0.1840719,
0.2413323,
-0.02405866,
-0.1441543,
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0.4329356,
0.2013946,
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0.2816928,
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0.1258155,
-0.4642982,
0.05063273,
-0.1677719,
-0.009259154,
0.07680728,
-0.04234328,
0.1... |
Peripheral nerve conduction velocities in chain-saw operators. | The motor, sensory and mixed nerve conduction velocities of median and posterior tibial nerves were measured in seventeen forest workers engaged in chain-saw operation for 2 to 16 yr (mean 12 yr). The conduction velocities were significantly diminished in the distal part of the upper limb. The sensory nerve conduction ... | 195,108 | [
0.137754,
0.133361,
0.06511442,
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0.5009663,
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0.02700629,
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0.02750209,
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0.1146026,
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0.1732463,
0.07913649,
... |
Spontaneous mutations in ageing human cells: studies using a Herpesvirus probe. | Several fundamental theories of ageing postulate that spontaneous mutations increase in somatic cells as they age. This has not until recently been directly tested in mammalian cells, because of the problem of estimating mutation rate in declining cell populations. One possible approach is to infect cells with lytic vi... | 195,146 | [
-0.01802714,
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0.08372521,
0.2401506,
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0.06992362,
0.1998201,
0.1240512,
0.02264016,
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0.04184888,
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0.5922687,
0.5647461,
0.09882529,
-0.235961... |
[Acupuncture for pains of the face and the head is there any reasonable application? (author's transl)]. | The physiological bases of the treatment with Acupuncture as well as its practical application in pain therapy were discussed at the meeting of the ORL-Society of Munich on the 4th December, 1976. | 195,167 | [
0.09686968,
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0.08515846,
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0.1004929,
0.1783791,
0.06860647,
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... |
[The clinical entity of primary tracheal cylindroma (author's transl)]. | On the grounds of 5 own observations of primary tracheal cylindroma and under consideration of the cases mentioned in literature on this subject, the repeatingly occurring and, therefore, probably typical characteristics of this kind of tumour were described. In the course of the disease, three phases may quite easily ... | 195,168 | [
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0.266351,
0.0756212,
0.565013,
0.05239305,
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... |
Acetylcholine and cAMP in adrenal medulla:indirect effect. | Catecholamine release and cAMP accumulation were studied in bovine adrenal medulla slices in vitro. Acetylcholine (10(-4) M) and salbutamol (10(-6) M) caused increased release of catecholamines and accumulation of cAMP. Incubation in Ca2+ -free medium abolished the release of catecholamines and the increase of cAMP cau... | 195,228 | [
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0.09832997,
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0.08206031,
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0.6040553,
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0.1047... |
Facts and reflections on thalamocortical reverberation of impulses. | Experiments on cats, either unanesthetized or anesthetized with various doses of pentobarbital, showed that the cortical rhythmic after-discharge ("slow after-activity"), which has been regarded as a manifestation of reverberation of impulses in thalamocortical circuits [17], consists of a burst of spontaneous "spindle... | 195,232 | [
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0.06443129,
0.1988822,
0.09411455,
0.0118888,
0.2710408,
0.03363572,
... |
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