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The design and development of the online pharmaceutical service was based on the Dáder methodology for pharmaceutical care and Service Experiment Blueprint concepts, enabling the design of service characteristics and functionalities required by chronic patients [39, 42].
method
Methods
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6 See for example studies of Morocco by Haddad and Harrison (1993); Venezuela by Aitken and Harrison (1999); Bulgaria and Romania by Konings (2000); Russia by Yudaeva et al. (2003); the Czech Republic by Kosova (2004); and China by Abraham, Konings and Slootmaekers (2006).
background
1. Introduction
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The majority of breeding female kin settles in close spatial proximity (on average, 72% of close kin are established within a females’ 30-m home range; see Viblanc et al. 2010).
background
Materials and methods
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2cc6ff899bf17666ad35893524a4d61624555ed7
[2] proposed two metrics to generalize FTLE in uncertain unsteady flows: D-FTLE and FTLE-D.
background
2.2 Uncertain and Ensemble Flow Visualization
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It creates the final layout of the biochip, consisting of the placement of microfluidic modules such as mixers and storage units, the routes that droplets take between different modules, and other geometrical details [53].
background
A. Scheduling and Module Placement
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These results suggested that an ABI,0.9 and high baPWV might be related to LVH. Previous studies had reported that a low ABI might be related to the interarm SBP difference and LVH [4,33,34].
result
Discussion
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172d65fb8159e03babd3ac2fa4846c9fd34059d5
It has been reported that SB243213, a selective 5-HT2C neutral antagonist (Bromidge et al. 2000), reversed the subchronic PCP-induced impairment in rat reversal learning (McLean et al. 2009a).
background
Introduction
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04b600c385b0ed98e79d43f6a74da47b1532344d
Src family kinases also play important roles in the spatial control of ROS production by cells through regulation of NADPH oxidases (11, 12, 14, 24).
background
dca46c3563f17379d07ebafee4f89eda34afe871
0e533d05e08206b74f98cbe411c36f2878ded8d5
Among them one of the most widely used is the residual network (ResNet) [8], which uses short cut to alleviate training difficulties of very deep networks.
background
2 Related Works
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The rationale behind the proposed solution is that autoencoders are able to capture a reduced dimensionality representation of the input data, still retaining important characteristic information, as shown in [27, 28] for forensic purposes.
background
Method
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272100433b5bb66ecf86da59974f8eb950625d25
This situation has been described for emerging CXCR4-using viruses later in disease progression, and was found to correlate with a decline of diversity [13].
background
Results
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a0ecd52bfe814e4941617cb23ba53b88a15397c7
, 2012), and the presence and type of vegetation (Huett et al., 2005; Gottschall et al., 2007; Comin et al., 1997).
background
Introduction
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df90f3e882609d15c298251608a5b48b69efb3b8
Cyclin A and PCNA expression have been shown to be up-regulated during S phase in numerous cells, including hepatocytes (24, 27, 28).
background
Results
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0cea3350a79ffd941e5cdbb1becbe759e1ef1626
This could be attributed to interindividual differences in the bioavailability of ingested pyrene, extent of pyrene transformation to 1- OHP, and polymorphism of drug-metabolizing enzymes (Viau et al. 2002).
background
310 A. RAMESH ET AL.
ead29e4944e84c9c74ac30447cf6a9147ab73ec8
989c9624226386c06971619adb3bf244007de797
3 China’s role in Apple’s global supply chain (e.g., Linden et al., 2009; Dedrick et al., 2010) have received a great deal of attention.
background
ddcd5506231ed723abd0c296088fc166fcc2aa4a
23e6dfc7f7543f87974dc7e74ff19edfcbf4e7e2
The proportion of long-chain poly-unsaturated FAs (in particular arachidonic acid, 20:4 n-6) and the average degree of FA unsaturation in skeletal muscle membrane PLs has been shown to correlate positively with insulin sensitivity (Borkman et al., 1993; Pan et al., 1995), whereas the proportion of 16:0 in both skeletal...
background
Introduction
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The Topic model (Griffiths et al., 2007; Steyvers & Griffiths, 2007) is based on the idea that context regions are collections of words that have been sampled from a mixture of latent topics.
background
2.3.2. Topic model
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It was estimated that among a total of 288,009 hospitalized survivors of neurotrauma in the United States in 2003, 124,626 patients developed long-term disability resulting in significant demand on rehabilitation services (Selassie et al., 2008).
background
Introduction
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The reversible Michaelis-Menten kinetics is a three-step mechanism containing three separate steps: (i) binding the enzyme E to the substrate S, (ii) the reversible catalytic conversion between the enzyme-substrate ES and the enzyme-product EP complexes, and (iii) binding of the enzyme E to product P (Heinrich and Schu...
method
Fundamental enzyme mechanism
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Pain Relief/Disability/QoL Improvement With the exception of the 2 NEJM RCTs and a smaller RCT that reported no benefit of VP versus SHAM [4, 5] or NSM [11, 12] the vast majority of prospective comparative studies (Tables 1 and 2) support the superiority of VAPs versus NSM [13–27], with only 1 newer study reporting bet...
method
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2532ccba6b98a0340e5e45aa94727d77c0afdeac
In addition, convergent studies (Langleben et al. 2001; Rubia et al. 2005; Silk et al. 2016; Team 2000) have reported that the pathophysiology of ADHD exhibits abnormalities in neural systems that are mainly related to cognitive control and motor functions.
background
Discussion
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e064573ea1cc22ca402efb5e140f06642bd37f77
…plants exposed to increased content of non humified nutrients can be affected by many mechanisms, such as damages in chloroplast ultrastructure, carbon supply depletion and disturbances in photosynthesis, which may result in stunted root growth and leaf chlorosis (Bitts anszky et al., 2015).
background
3. Results and discussion
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, 1994; Meijer, 1996) and by RNAi (Fire et al., 1998; Tabara et al., 1998; Tabara et al., 1999; Grishok et al., 2000; Klink and Wolniak, 2000; Klink and Wolniak, 2001), using dsRNA probes derived from cyclin A and from cyclin B cDNAs that we isolated from a M.
background
Chiawei W. Tsai and Stephen M. Wolniak*
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In mammalian cells, cyclin D–CDK4/6 and cyclin E–CDK2 complexes are required to promote cell cycle entrance from quiescence, progression through the G1 phase and transition from G1 into S phase in response tomitogenic stimulation (Sherr, 1995; Malumbres and Barbacid, 2001; Chulu and Liu, 2009).
background
Results
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In fact, their basis are MP grammars, where multiset transformations are regulated by functions in a deterministic way [19].
background
1. Introduction
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Bone from McCune-Albright syndrome patients shows a fibrous infiltrate, significant increases in trabecular bone formation, ablation of the marrow cavity, and an increased propensity to deformation and fracture [35].
background
Discussion
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Thus, while the current study reproduces the spectral EEG changes induced by propofol in more detail than (Hutt and Longtin, 2010) which did not focus on reproducing spectral EEG peaks themselves, but instead on bi-phasic power changes, it is limited to the first phase of the bi-phasic response.
background
Scope and extensions
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TfMA had lower sequence identity of 33~27% with α-amylase II from Thermoactinomyces vulgaris (Tonozuka et al. 1993), maltogenic amylase from Thermus sp. IM6501 (Kim et al. 1999), neopullulanase from Geobacillus stearothermophilus (Cheong et al. 2002), glucosidase from Thermotoga maritima (Lee et…
background
Results
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It has proven a suitable method for determining the content of a CPT curriculum.(14,15,17) The modified Delphi process took place between January and July 2017 and comprised the following: a systematic literature search; selection of a European expert panel; and development of a Web-based questionnaire and its modifica...
method
Methods
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Others implicitly set γ ≡ 0 to investigate the relationship between damages and socioeconomic vulnerability; see Kellenberg and Mobarak (2008), Bakkensen (2013), Bakkensen and Mendelsohn (2016) and Geiger et al. (2016).
background
5 Methods
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…have been based on unselected populations of animals although it might be more productive to study this issue in animals that show an innate predisposition to express high or low levels of anxiety 18 Introduction (Brush, 2003; Landgraf & Wigger, 2002; Lister, 1990; Steimer & Driscoll, 2003).
background
1.4 Selective breeding
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subtilis perRBS mutant, the expression level of fur is known to be less than one-third of those of katA, mrgA, and ahpC (Fuangthong et al., 2002; Faulkner et al., 2012).
background
Results
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Immunoprecipitation and western blot Protein extraction, western blots and immunoprecipitations were performed as previously described (Pentimalli et al., 2008).
method
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The high concentration of Ca activates mitochondrial calcium-sensitive K channels (mtKca) and mitochondrial nitric oxide synthase (mtNOS), which increases the levels of nitric oxide (NO) (Figure 3) [21, 23, 33, 64, 100, 101, 107–115].
background
cf3d0d63e8ed6cb6bac03c00d21d8b87c83a39d5
3d8487b14c2aae003bcdf41f857e0b51c91f285f
Responses of several NTD models to various nutrients have been tested, with some showing responsiveness and others resistance to supplementation or to deprivation [21-26,28,34].
background
L3P
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Moreover, a resting state functional connectivity analysis showed that the TPJa and TPJp are embedded in different functional networks: the right TPJa activity interacted with the bilateral IPL, the ventral prefrontal network, and the anterior insula, which are often associated with ventral attention network [41,44], w...
background
Discussion
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Moreover, still others have reported that the selective inhibition of Ang-2 activity promotes blood reperfusion following ischaemia through the recruitment of inflammatory cells and combination with VEGF [5, 9].
background
Background
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ATP7A and ATP7B are P1B-type ATPases, which use the energy released from ATP hydrolysis to transport Cu across Golgi membranes (Jayakanthan et al. 2017; Lutsenko et al. 2008; Yatsunyk and Rosenzweig 2007; Yu et al. 2017b).
background
Introduction
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The cluster goodness can be additionally evaluated through measuring the purity, entropy and F-Measure [23, 24, 25].
background
3.2 Clustering
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According with our previous results (Orihuela & Croxatto 2001, Orihuela et al. 2001, 2003) and those shown in this paper we propose a model indicating that the nongenomic pathway utilised by E2 to accelerate oviductal transport of oocytes in cycling rats involves successive activation of the…
result
Discussion
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These studies have generally found that cells from immature ventricles, compared with adult myocytes, display 1) a reduction in the density of outward K currents (28, 51), 2) greater activity and expression of Na /Ca(2) exchange (NCX) (2), and 3) intracellular Ca(2) transients that depend less on sarcoplasmic reticulum...
background
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Amino acid residues involved in the iron binding site of dioxygenases (Britsch et al., 1993) are conserved in the above-mentioned dioxygenases (asterisks in Figure 3).
background
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192a5af24f95a45c550c0ccabd4e468a5638b37e
Mechanistically, gametic and somatic DMRs both require the maintenance of DNA methylation by DNMT1 (Caspary et al., 1998; Bhogal et al., 2004).
background
DISCUSSION
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The first experiment was purposed for foreign language education (Kanda et al., 2004 d), but there was no mechanism for long-term interaction implemented in Robovie.
background
3 Field experiments
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The caeca of chicks are the intestinal organs that contain the highest loads of the bacterium (Beery et al., 1988; Hendrixson and DiRita, 2004).
background
Results
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NP3L [10] is consistently outperformed by our methods, while for UPnP [8] our NPnLupC outperforms it in the noisy cases.
method
5.1. Robustness
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Indeed, in response to dual tasking, patients with PD and idiopathic fallers walk more slowly and reduce their average swing times (Springer et al. 2006; Yogev et al. 2005).
background
Discussion
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As a covariate, the effect of exercise on parameters was examined both as a two-point proportional effect between the two levels of high intensity and the lesser prolonged intensity [2–4] and also as a single additive effect.
background
Methods
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1http://owl.man.ac.uk/factplusplus 2http://kaon2.semanticweb.org/ The meta-data is generated by code written for SWOOP [9], and provides the details of the expressivity (i.e. the constructs present in the ontology) together with the number of classes, object properties, data properties, individuals, class axioms, prop...
method
3 Methodology
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The variables selected for the regression analyses were those that correlated significantly with serum FGF21 or FFAs and those that have been shown to be associated with plasma levels of these proteins [4,9].
method
Methods
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In rare cases where PCR did not yield amplicons, the primers 63f (50 CAG GCC TAA CAC ATG CAA GTC 30) and 1387r (50 GGG CGG WGT GTA CAA GGC 30) (Marchesi et al. 1998) were used.
method
METHODS
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Proposed approach is compared with supervised variable selection methods: maximum mutual information minimal redundancy (MIMR) method [18] and HITTON_PC and HITTON_MB [19] methods.
method
3 Experiments
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We obtained 658–667 bp of mtDNA control region sequences for each species from published data sets (Kulikova et al. 2005, 2012; Peters et al. 2005, 2008, 2012b, 2014; Lavretsky et al. 2014; Table S3, Supporting information), supplementing these data with new sequences.
method
Methods
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Only 15% cases undergoing cataract surgery in 1995 had IOL implantation while almost 90% of cases had IOL implantation in 2006 [24, 38].
background
Discussion
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There is a significant increase in the levels of cariogenic bacteria in the saliva and plaque of patients undergoing fixed appliance treatment.(21,22) However, during the initial phase of caries growth, S mutans is the most frequently associated microorganism.
background
DISCUSSION
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These clusters of informative voxels, along with a cluster implicating the occipital cortex, have also been consistently found in neuroimaging studies using statistical parametric mapping (Bush et al., 2000; Colibazzi et al., 2010; Gerber et al., 2008; Hagan et al., 2009; Killgore and Yurgelun-Todd, 2004; Narumoto et a...
result
Discussion
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…in the dependability definition (see Section 2.4 below), the attribute safety, since it is also included in the dependability definitions seen in Section 1, is directly included in the definition (see (Rüdiger et al., 2007a) for a definition of the remaining attributes in a behavioral context).
background
2.2 Behavior and Mission of Autonomous System
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Hence, with the understanding that measuring instruments need to be used by physical therapists in order to objectively quantify alterations affecting mainly the thoracic and lumbar regions of the spine, and to establish the criteria for planning and following up their interventions13, the aims of the present study are...
background
Introduction
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Ectopic activation of Hedgehog activity in PDCs was obtained either through expression of a dominant-active version of GLI2 [41] or a dominant-active form of Smoothened (SmoA1).
background
RESULTS AND DISCUSSION
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Such training has been shown to reduce resting CRP and IL-6 (Mendham et al. 2014), and improve glycaemic control (Andersen et al. 2014) and body composition (Andersen et al. 2010).
background
Introduction
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(Massie and Holland, 1984; Ciaramella and Poli, 2001; Uchitomi et al., 2003; Katz et al., 2004; Ell et al., 2005; Boyd et al., 2012; Kim et al., 2012; Mitchell et al., 2012; Palmer et al., 2012; Pirl et al., 2012; Tada et al., 2012; Warmenhoven et al., 2012; Yu et al., 2012).
background
Discussion
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We ultimately selected a 2007 study using Medicare Advantage data to estimate the direct medical costs attributable to CVD events [26], and a 2002 Canadian study to determine age-specific productivity losses due to events [30].
method
Methods
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In the ISO standard (Bunt et al., 2012), FSs can theoretically be discontinuous or run across turn boundaries.
background
2.1. Turns and Dialog acts
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In crustacean, apart from functioning as a digestive gland, hepatopancreas is also an important immune organ that functions as a primary site to synthesize and excrete immune molecules, such as beta-1,3-glucan binding protein (LGBP) [16], antibacterial peptide (AMP) [17], lectin or lectin related proteins and others [1...
background
Introduction
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…showed that imaging or therapeutic agents larger than the BBB’s exclusion threshold of 400 Da could be successfully delivered by FUS with microbubbles (Alonso et al. 2013; Choi et al. 2007; Choi et al. 2010a; Hynynen et al. 2001; Kinoshita et al. 2006; Marquet et al. 2014; Shen et al. 2014).
background
DISCUSSION
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Ramirez et al. (2015) reported a lower LOD, thus higher analytical sensitivity, of kDNA PCR compared to Sat-DNA PCR tests for T. cruzi VI.
result
3. Results and discussion
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[24] showed that, for this choice of joint feature vector, loss-augmented inference can be performed optimally using an efficient greedy algorithm.
method
1 Introduction
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SEQUENCE KBT [10] PPM [15] LBPT [20] KCF [9] Proposed Average success rate 164 100 88 165 66
background
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5cf2fa811b4b6d5e83e6e3d9af27cacb82c4510b
We undertook the present study because recent availability of new fibroblast markers has reduced the difficulty in addressing this issue (7, 8).
background
Introduction
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In addition, the P-VS profiles of SA1 and SA2 have only one inflection point, at the onset of the average Si-O coordination number’s increase from 6 to 6+ (Brazhkin et al. 2011; Wu et al. 2012; Murakami and Bass 2010, 2011).
background
Results and discussion
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at least 60–85%) fasting triglycerides, in agreement with previous data obtained in healthy subjects (15, 39).
result
Discussion
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These results are in keeping with previous research investigating the processing of kana and alphabetic languages (Bolger et al., 2005; Ischebeck et al., 2004; Nakamura et al., 2005; Sakurai et al., 1993, 2000; Tan et al., 2005a; Thuy et al., 2004), as well as kanji and logographic languages…
result
4. Discussion
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We compare our results with regular Gibbs sampling (Gibbs) and the approach proposed in Venugopal and Gogate [30] (cgibbs), where they use clustering algorithms such as KMeans to derive an approximate MLN and then sample this MLN using regular Gibbs sampling.
method
5 EXPERIMENTS
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Previous comparisons of transcriptome content [10], gene expression patterns [11-13], and gene function [14,15] between Amborella and other flowering plant species have suggested that much of the floral development program that has been characterized in Arabidopsis, snapdragon and maize existed in the last common ances...
background
Background
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Treatment options include surgical excision, chemotherapy, immunotherapy with rituximab for patients with positive CD 20 immunohistochemistry, or radiosurgery.(1-30) For patients without systemic involvement, external beam radiotherapy (EBRT) is often used after histopathologic confirmation.
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Carlos Bianciotto, MD; Carol L. Shields, MD; Sara E. Lally, MD; Jorge Freire, MD; Jerry A. Shields, MD
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For this analysis we use the two SI distributions observed from investigations of the first 100 pH1N1 cases in South Africa [22]: (1) the SI distribution between primary cases and laboratoryconfirmed secondary cases only (39%, 24%, 14%, 17%, 3% and 3% for day 1 to 6 respectively), and (2) the SI distribution between pr...
method
Methods
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DAA cases were performed with a slight modification of the technique described by Lovell [15], with anterior capsulotomy and subsequent repair, the use of a standard operating table with a table mounted femoral elevator (Omni-Tract Surgical, St. Paul, Minnesota), selective soft tissue releases based on the mobility of ...
method
Methods
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With data from the Southwest Oncology Group (SWOG 8794) for the use of adjuvant radiation therapy in high-risk patients (21), and Messing trial results demonstrating an advantage in survival for long-term ADT in lymph node-positive patients (22), good pathologic data are an important step toward multi-modality approach...
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DIscussIOn
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Internal consistency for the PIWSUR total score were reported to be excellent by (Burns et al. 1996) (Cronbach’s alpha = 0.92), and for the subscales was fair to good with alphas ranging from 0.77 to 0.88.
method
Method
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Two PTF1 binding sites are present in the 2.3 kb Ptf1a regulatory sequence Sequence analysis of the two highly conserved peaks in the 2.3 kb enhancer revealed the presence of two PTF1 binding sites, referred to here as the proximal (P) and the distal (D) PTF1 sites (Masui et al., 2008).
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Activity of the 2.3 kb Ptf1a 5 enhancer
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Then we make quantitative comparisons with other state-of-the-art approaches on the 5-class and 6-class collective datasets, including RSTV approach in [7], a joint tracking and recognition flow model in [15], a complex hierarchical model in [5], a bayesian BORD method in [1] and a discriminative latent model in [17].
method
7.1 Activity Recognition
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FISH was carried out according to Pinkel et al. (1986) using 5S rDNA probes obtained by PCR from Prochilodus genomic DNA using the primers A (5_-TACGCCCGATCTCG TCCGATC-3_) and B (5_-CAGGCTGGTATGGCCGTAAGC-3_) (Pendás et al., 1994).
method
Materials and Methods
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Studies on HA have shown previously that HA have the ability to decrease respiratory stress, and reduce hyperactivity in eastern rainbowfish fingerlings exposed to low pH during 96 h exposures (Holland et al., 2014a).
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4. Discussion
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8-kb genomic fragment containing all of the noncoding exons demonstrated tissue-specific expression in transgenic mice (Drews et al. 2005).
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Present Address:
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A similar behaviour was found in the context of Higgs production in association with bottom quarks [31].
result
3.3 Four- and five-flavour scheme comparison
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Previous research find that the VOT value of aspirated decreases and overlaps with that of lenis for younger speakers, but not for older speakers (Jin 2008, Kang 2014, Kang and Guion 2008, Silva 2006, Wright 2007).
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1. Introduction
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The developmental changes associated with puberty, pregnancy, lactation and involution of the mammary gland have been extensively studied and signaling pathways initiated by both membrane and nuclear receptors are essential for coordination of these events [1].
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Introduction
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Many estimation processes applies the probabilistic approach to determine the state of environment because of the uncertainties of measurements [12,15].
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C. Target Model
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Figures 3 and 4 present in silico plasma profiles from the final, validated analog under fasting and fed conditions, respectively, shown with the GITT model predictions from [17].
method
Results
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…and often impossible task (see, e.g., Herrmann et al., 1990; Saunders et al., 1992; Anderson et al., 2010; Franklin, 2010), and stature estimations may vary largely depending on the applied method (see, e.g., Sciulli et al., 1990; Raxter et al., 2007; Siegmund, 2010; Carretero et al., 2012).
method
Methods
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MEDLINE), one can find the elements of the PICO structure, but rarely explicitly annotated (Dawes et al., 2007).
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1 Introduction
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The pulvinar and much of the thalamus are centres of high-order (cortical to cortical) relay connections and their activation in early hypoglycemia may reflect arousal-enhanced relay of integrated sensory information to other cortical areas (reviewed by Sherman, 2007).
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Discussion
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…Screen / Esc Printer-friendly Version Interactive Discussion D iscussion P aper | D iscussion P aper | D iscussion P aper | D iscussion P aper | Ocean is unphysical, and subtract it from each along-track row; this approach is similar to those applied in previous studies (Boersma et al., 2007).
result
6 Case study over Dubai, UAE
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Native Skp1 sequences were employed because a previous study showed that N- or C-terminal peptide tags interfere with its hydroxylation and activity in cells [10].
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Skp1 modification is O2 dependent
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capillary endothelial cells [16;17] - we have been evaluating its participation in the response to respiratory tract infections.
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Introduction
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We took inspiration from previous research done in the context of novel IDEs ([15], [16] and [17]) and used abstraction to present a concise view of the entities of a software model.
method
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The settings for the Maras’ and Fan’s strategies shown in Table 1 are consistent with those in their original studies of [4] and [7].
method
4. Numerical Experiments
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vinifera (P28343, Coutos-Thevenot et al., 2001; Giorcelli et al., 2004; Zhu et al., 2004) that have been successfully used in gene transfer experiments.
method
Results and discussion
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the thoracic and lumbar curvatures: (1) X-ray examination from which the Cobb angles (CA) of both curvatures were obtained, and (2)
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…with 675 kHz scanning pencil beam sonar and a 200 kHz multibeam sonar for near-bottom bathymetric surveys, both with vertical resolution as high as centimeters to decimeters depending on acquisition parameters [Singh et al., 2000; Whitcomb et al., 2000; Roman et al., 2005; Ferrini et al., 2005b].
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1. Introduction
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