Datasets:
vgainullin
/
xciting_data

Dataset card Data Studio Files
xet
 Community
1
paragraph_index
int64
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cites
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sentences
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3
INTRODUCTION
0
null
null
18,948,277
null
This can be done by emailing us or getting involved directly in developing the database, which is an Open Source project available at our GoogleCode site (http://code.google.com/p/rnavirusdb).
null
192
39,316
0
false
null
null
This can be done by emailing us or getting involved directly in developing the database, which is an Open Source project available at our GoogleCode site (http://code.google.com/p/rnavirusdb).
true
true
true
true
true
6,776
4
INTRODUCTION
1
10
[ "B10" ]
18,948,277
pmid-10364305
Some of the data and tools on the RNA Virus Database can be found elsewhere, but not all of them can, e.g.
[ "10" ]
106
39,317
0
false
Some of the data and tools on the RNA Virus Database can be found elsewhere, but not all of them can, e.g.
[]
Some of the data and tools on the RNA Virus Database can be found elsewhere, but not all of them can, e.g.
true
true
true
true
true
6,777
4
INTRODUCTION
1
10
[ "B10" ]
18,948,277
pmid-10364305
NCBI's Genome site provides genomic overviews of virus species and pairwise alignments of other isolates to the reference sequence, but it does not provide multiple alignments or complete translated genomes as we do.
[ "10" ]
216
39,318
0
false
NCBI's Genome site provides genomic overviews of virus species and pairwise alignments of other isolates to the reference sequence, but it does not provide multiple alignments or complete translated genomes as we do.
[]
NCBI's Genome site provides genomic overviews of virus species and pairwise alignments of other isolates to the reference sequence, but it does not provide multiple alignments or complete translated genomes as we do.
true
true
true
true
true
6,777
4
INTRODUCTION
1
10
[ "B10" ]
18,948,277
pmid-10364305
Similarly, its general Entrez site provides pair-wise alignments of the query sequence and similar sequences in the database, plus a phylogenetic tree calculated from those distances; however, no multiple alignment is built.
[ "10" ]
224
39,319
0
false
Similarly, its general Entrez site provides pair-wise alignments of the query sequence and similar sequences in the database, plus a phylogenetic tree calculated from those distances; however, no multiple alignment is built.
[]
Similarly, its general Entrez site provides pair-wise alignments of the query sequence and similar sequences in the database, plus a phylogenetic tree calculated from those distances; however, no multiple alignment is built.
true
true
true
true
true
6,777
4
INTRODUCTION
1
10
[ "B10" ]
18,948,277
pmid-10364305
We also corrected the (few) errors in the GenBank entries, and our database records features such as RNA editing (10) that make genome translation problematic.
[ "10" ]
159
39,320
1
false
We also corrected the (few) errors in the GenBank entries, and our database records features such as RNA editing that make genome translation problematic.
[ "10" ]
We also corrected the (few) errors in the GenBank entries, and our database records features such as RNA editing that make genome translation problematic.
true
true
true
true
true
6,777
5
INTRODUCTION
0
null
null
18,948,277
null
We have, therefore, created the RNA Virus Database as a user-friendly site devoted to RNA viruses, providing essential genomic data and tools (discussed in more detail below) and links to the other virus Web sites.
null
214
39,321
0
false
null
null
We have, therefore, created the RNA Virus Database as a user-friendly site devoted to RNA viruses, providing essential genomic data and tools (discussed in more detail below) and links to the other virus Web sites.
true
true
true
true
true
6,778
5
INTRODUCTION
0
null
null
18,948,277
null
The three main features are as follows.
null
39
39,322
0
false
null
null
The three main features are as follows.
true
true
true
true
true
6,778
5
INTRODUCTION
0
null
null
18,948,277
null
Provide multiple whole-genome alignments, gene and whole-genome translations for all RNA virus speciesIdentification and taxonomic searching facilityGuidance to other web resources.
null
181
39,323
0
false
null
null
Provide multiple whole-genome alignments, gene and whole-genome translations for all RNA virus speciesIdentification and taxonomic searching facilityGuidance to other web resources.
true
true
true
true
true
6,778
6
INTRODUCTION
0
null
null
18,948,277
null
Provide multiple whole-genome alignments, gene and whole-genome translations for all RNA virus species
null
102
39,324
0
false
null
null
Provide multiple whole-genome alignments, gene and whole-genome translations for all RNA virus species
true
true
false
true
false
6,779
7
INTRODUCTION
0
null
null
18,948,277
null
Identification and taxonomic searching facility
null
47
39,325
0
false
null
null
Identification and taxonomic searching facility
true
true
false
true
false
6,780
8
INTRODUCTION
0
null
null
18,948,277
null
Guidance to other web resources.
null
32
39,326
0
false
null
null
Guidance to other web resources.
true
true
true
true
true
6,781
0
INTRODUCTION
1
1
[ "B1", "B2" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Mycoplasma pneumoniae infections may be manifested in upper respiratory tract, lower respiratory tract, or both, presenting sore throat, hoarseness, fever, chills, cough, coryza, malaise, wheezing, dyspnea, progression to bronchopneumonia or lobar pneumonia requiring hospitalization, and extrapulmonary symptoms (1).
[ "1", "2" ]
317
39,327
1
false
Mycoplasma pneumoniae infections may be manifested in upper respiratory tract, lower respiratory tract, or both, presenting sore throat, hoarseness, fever, chills, cough, coryza, malaise, wheezing, dyspnea, progression to bronchopneumonia or lobar pneumonia requiring hospitalization, and extrapulmonary symptoms.
[ "1" ]
Mycoplasma pneumoniae infections may be manifested in upper respiratory tract, lower respiratory tract, or both, presenting sore throat, hoarseness, fever, chills, cough, coryza, malaise, wheezing, dyspnea, progression to bronchopneumonia or lobar pneumonia requiring hospitalization, and extrapulmonary symptoms.
true
true
true
true
true
6,782
0
INTRODUCTION
1
1
[ "B1", "B2" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
This broad spectrum of symptoms cannot be differentiated from symptoms of the infections caused by other bacteria or viruses.
[ "1", "2" ]
125
39,328
0
false
This broad spectrum of symptoms cannot be differentiated from symptoms of the infections caused by other bacteria or viruses.
[]
This broad spectrum of symptoms cannot be differentiated from symptoms of the infections caused by other bacteria or viruses.
true
true
true
true
true
6,782
0
INTRODUCTION
1
2
[ "B1", "B2" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
The specific diagnosis M. pneumoniae infection is important because treatment with β-lactam antibiotics is ineffective, whereas treatment with macrolides or tetracyclines may markedly reduce the duration of illness (2).
[ "1", "2" ]
219
39,329
1
false
The specific diagnosis M. pneumoniae infection is important because treatment with β-lactam antibiotics is ineffective, whereas treatment with macrolides or tetracyclines may markedly reduce the duration of illness.
[ "2" ]
The specific diagnosis M. pneumoniae infection is important because treatment with β-lactam antibiotics is ineffective, whereas treatment with macrolides or tetracyclines may markedly reduce the duration of illness.
true
true
true
true
true
6,782
0
INTRODUCTION
1
1
[ "B1", "B2" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
However, reference laboratory methods for the diagnosis of M. pneumoniae infection have not been established.
[ "1", "2" ]
109
39,330
0
false
However, reference laboratory methods for the diagnosis of M. pneumoniae infection have not been established.
[]
However, reference laboratory methods for the diagnosis of M. pneumoniae infection have not been established.
true
true
true
true
true
6,782
1
INTRODUCTION
1
3
[ "B3", "B5" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
Culture is time-consuming and relatively insensitive.
[ "3", "5" ]
53
39,331
0
false
Culture is time-consuming and relatively insensitive.
[]
Culture is time-consuming and relatively insensitive.
true
true
true
true
true
6,783
1
INTRODUCTION
1
3
[ "B3", "B5" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
The introduction of polymerase chain reaction (PCR) for detection of M. pneumoniae in respiratory tract specimens has lessened the importance of culture, enabling rapid and sensitive detection.
[ "3", "5" ]
193
39,332
0
false
The introduction of polymerase chain reaction (PCR) for detection of M. pneumoniae in respiratory tract specimens has lessened the importance of culture, enabling rapid and sensitive detection.
[]
The introduction of polymerase chain reaction (PCR) for detection of M. pneumoniae in respiratory tract specimens has lessened the importance of culture, enabling rapid and sensitive detection.
true
true
true
true
true
6,783
1
INTRODUCTION
1
3
[ "B3", "B5" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
However, PCR cannot differentiate colonization from infection nor can detect organisms in the convalescent phase (3-5).
[ "3", "5" ]
119
39,333
0
false
However, PCR cannot differentiate colonization from infection nor can detect organisms in the convalescent phase.
[ "3-5" ]
However, PCR cannot differentiate colonization from infection nor can detect organisms in the convalescent phase.
true
true
true
true
true
6,783
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Despite its drawbacks, for the use in immunosuppressed persons who are unable to mount an antibody response, serologic diagnosis of M. pneumoniae infections has long been the cornerstone of diagnosis and epidemiologic study (1).
[ "1", "6", "1", "7" ]
228
39,334
1
false
Despite its drawbacks, for the use in immunosuppressed persons who are unable to mount an antibody response, serologic diagnosis of M. pneumoniae infections has long been the cornerstone of diagnosis and epidemiologic study.
[ "1" ]
Despite its drawbacks, for the use in immunosuppressed persons who are unable to mount an antibody response, serologic diagnosis of M. pneumoniae infections has long been the cornerstone of diagnosis and epidemiologic study.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
The complement fixation (CF) test was the standard serologic method for the diagnosis of M. pneumoniae infection.
[ "1", "6", "1", "7" ]
113
39,335
0
false
The complement fixation (CF) test was the standard serologic method for the diagnosis of M. pneumoniae infection.
[]
The complement fixation (CF) test was the standard serologic method for the diagnosis of M. pneumoniae infection.
true
true
true
true
true
6,784
2
INTRODUCTION
1
6
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
The CF test, using a glycolipid antigen, provides non-specific reactions and therefore lacks sensitivity (6).
[ "1", "6", "1", "7" ]
109
39,336
1
false
The CF test, using a glycolipid antigen, provides non-specific reactions and therefore lacks sensitivity.
[ "6" ]
The CF test, using a glycolipid antigen, provides non-specific reactions and therefore lacks sensitivity.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Alternative formats adapted for commercial serologic assays include indirect immunofluorescence assay (IFA), particle agglutination (PA) assay, and enzyme-linked immunoassay (EIA).
[ "1", "6", "1", "7" ]
180
39,337
0
false
Alternative formats adapted for commercial serologic assays include indirect immunofluorescence assay (IFA), particle agglutination (PA) assay, and enzyme-linked immunoassay (EIA).
[]
Alternative formats adapted for commercial serologic assays include indirect immunofluorescence assay (IFA), particle agglutination (PA) assay, and enzyme-linked immunoassay (EIA).
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
IFAs for M. pneumoniae provide accurate, quantitative serological data, but their interpretation is subjective and a fluorescence microscope is necessary (1).
[ "1", "6", "1", "7" ]
158
39,338
1
false
IFAs for M. pneumoniae provide accurate, quantitative serological data, but their interpretation is subjective and a fluorescence microscope is necessary.
[ "1" ]
IFAs for M. pneumoniae provide accurate, quantitative serological data, but their interpretation is subjective and a fluorescence microscope is necessary.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
The PA assay is the most widely used method in Korea because it is easy to perform and give quantitative results with acceptable sensitivity.
[ "1", "6", "1", "7" ]
141
39,339
0
false
The PA assay is the most widely used method in Korea because it is easy to perform and give quantitative results with acceptable sensitivity.
[]
The PA assay is the most widely used method in Korea because it is easy to perform and give quantitative results with acceptable sensitivity.
true
true
true
true
true
6,784
2
INTRODUCTION
1
7
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
However, the ambiguity in the interpretation of agglutination, non-specific reactions, and inability to discriminate between IgG and IgM are drawbacks of the PA assay for the diagnosis of M. pneumoniae infection (7).
[ "1", "6", "1", "7" ]
216
39,340
1
false
However, the ambiguity in the interpretation of agglutination, non-specific reactions, and inability to discriminate between IgG and IgM are drawbacks of the PA assay for the diagnosis of M. pneumoniae infection.
[ "7" ]
However, the ambiguity in the interpretation of agglutination, non-specific reactions, and inability to discriminate between IgG and IgM are drawbacks of the PA assay for the diagnosis of M. pneumoniae infection.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Thus there is a need for EIA that can detect IgG and IgM separately to distinguish current from past infections.
[ "1", "6", "1", "7" ]
112
39,341
0
false
Thus there is a need for EIA that can detect IgG and IgM separately to distinguish current from past infections.
[]
Thus there is a need for EIA that can detect IgG and IgM separately to distinguish current from past infections.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
A few different EIA kits are now available in Korea, and some institutions have introduced them recently.
[ "1", "6", "1", "7" ]
105
39,342
0
false
A few different EIA kits are now available in Korea, and some institutions have introduced them recently.
[]
A few different EIA kits are now available in Korea, and some institutions have introduced them recently.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Changes in testing methods from PA to EIA could be confusing to clinicians because of differences between PA titer and EIA units; however, there is no available data for the Korean patients.
[ "1", "6", "1", "7" ]
190
39,343
0
false
Changes in testing methods from PA to EIA could be confusing to clinicians because of differences between PA titer and EIA units; however, there is no available data for the Korean patients.
[]
Changes in testing methods from PA to EIA could be confusing to clinicians because of differences between PA titer and EIA units; however, there is no available data for the Korean patients.
true
true
true
true
true
6,784
2
INTRODUCTION
1
1
[ "B1", "B6", "B1", "B7" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
We analyzed the performance of four commercial EIA kits sold in Korea and correlated the results with PA assay results.
[ "1", "6", "1", "7" ]
119
39,344
0
false
We analyzed the performance of four commercial EIA kits sold in Korea and correlated the results with PA assay results.
[]
We analyzed the performance of four commercial EIA kits sold in Korea and correlated the results with PA assay results.
true
true
true
true
true
6,784
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
It is well known that M. pneumoniae causes 40% or more cases of community-acquired pneumonia and as many as 18% of cases requiring hospitalization in children (1).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
163
39,345
1
false
It is well known that M. pneumoniae causes 40% or more cases of community-acquired pneumonia and as many as 18% of cases requiring hospitalization in children.
[ "1" ]
It is well known that M. pneumoniae causes 40% or more cases of community-acquired pneumonia and as many as 18% of cases requiring hospitalization in children.
true
true
true
true
true
6,785
0
DISCUSSION
1
8
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Recent epidemiologic studies indicated that M. pneumoniae are frequently involved as causative agents in upper or lower respiratory tract infections including common colds, pharyngitis, bronchitis, wheezing, and extrapulmonary disease in children aged less than 5 yr as well as in school ages and throughout the year wit...
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
365
39,346
1
false
Recent epidemiologic studies indicated that M. pneumoniae are frequently involved as causative agents in upper or lower respiratory tract infections including common colds, pharyngitis, bronchitis, wheezing, and extrapulmonary disease in children aged less than 5 yr as well as in school ages and throughout the year wit...
[ "8" ]
Recent epidemiologic studies indicated that M. pneumoniae are frequently involved as causative agents in upper or lower respiratory tract infections including common colds, pharyngitis, bronchitis, wheezing, and extrapulmonary disease in children aged less than 5 yr as well as in school ages and throughout the year wit...
true
true
true
true
true
6,785
0
DISCUSSION
1
8
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
M. pneumoniae had been isolated from the respiratory tract of 20-50% of asthmatic patients with acute exacerbations and patients with chronic stable asthma (8).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
160
39,347
1
false
M. pneumoniae had been isolated from the respiratory tract of 20-50% of asthmatic patients with acute exacerbations and patients with chronic stable asthma.
[ "8" ]
M. pneumoniae had been isolated from the respiratory tract of 20-50% of asthmatic patients with acute exacerbations and patients with chronic stable asthma.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Principi et al.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
15
39,348
0
false
Principi et al.
[]
Principi et al.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
evaluated the incidences of acute M. pneumoniae infection in 613 Italian children aged 2-14 yr with community-acquired lower respiratory infections.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
148
39,349
0
false
evaluated the incidences of acute M. pneumoniae infection in 613 Italian children aged 2-14 yr with community-acquired lower respiratory infections.
[]
evaluated the incidences of acute M. pneumoniae infection in 613 Italian children aged 2-14 yr with community-acquired lower respiratory infections.
false
true
true
true
false
6,785
0
DISCUSSION
1
9
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
EIA for M. pneumoniae-specific IgG/IgM antibodies indicated that M. pneumoniae was the causative agent in 25.6% of acute bronchitis (ranged from 19.3 to 52.9% over age groups), 28.0% of wheezing (22.6% to 50.0%), and 33.9% of pneumonia with infiltration on chest radiograph (20.0% to 54.6%) (9).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
295
39,350
1
false
EIA for M. pneumoniae-specific IgG/IgM antibodies indicated that M. pneumoniae was the causative agent in 25.6% of acute bronchitis, 28.0% of wheezing (22.6% to 50.0%), and 33.9% of pneumonia with infiltration on chest radiograph (20.0% to 54.6%).
[ "ranged from 19.3 to 52.9% over age groups", "9" ]
EIA for M. pneumoniae-specific IgG/IgM antibodies indicated that M. pneumoniae was the causative agent in 25.6% of acute bronchitis, 28.0% of wheezing (22.6% to 50.0%), and 33.9% of pneumonia with infiltration on chest radiograph (20.0% to 54.6%).
true
true
true
true
true
6,785
0
DISCUSSION
1
8
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
They also reported that 24.2% of pharyngitis were due to M. pneumoniae (8).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
75
39,351
1
false
They also reported that 24.2% of pharyngitis were due to M. pneumoniae.
[ "8" ]
They also reported that 24.2% of pharyngitis were due to M. pneumoniae.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Layani-Milon et al.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
19
39,352
0
false
Layani-Milon et al.
[]
Layani-Milon et al.
true
true
true
true
true
6,785
0
DISCUSSION
1
10
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
reported that a PCR-hybridization assay in nasal swab detected M. pneumoniae from 7.3% of children with influenza-like upper respiratory infections, ranging from 2.0 to 10.1% over the five period (10).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
201
39,353
1
false
reported that a PCR-hybridization assay in nasal swab detected M. pneumoniae from 7.3% of children with influenza-like upper respiratory infections, ranging from 2.0 to 10.1% over the five period.
[ "10" ]
reported that a PCR-hybridization assay in nasal swab detected M. pneumoniae from 7.3% of children with influenza-like upper respiratory infections, ranging from 2.0 to 10.1% over the five period.
false
true
true
true
false
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Our patients who were diagnosed as pneumonia with abnormal chest radiograph (group I) showed higher IgM positive rates than previous reports; ranging from 62.2% to 78.4% with 4 kinds of EIAs (Table 1).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
201
39,354
0
false
Our patients who were diagnosed as pneumonia with abnormal chest radiograph (group I) showed higher IgM positive rates than previous reports; ranging from 62.2% to 78.4% with 4 kinds of EIAs.
[ "Table 1" ]
Our patients who were diagnosed as pneumonia with abnormal chest radiograph (group I) showed higher IgM positive rates than previous reports; ranging from 62.2% to 78.4% with 4 kinds of EIAs.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Platelia detected IgM antibodies from 21.4% of group II patients (upper or lower respiratory infection except pneumonia with infiltrations) and 23.5% of group III patients (acute exacerbation of asthma), and other 3 IgM EIAs detected IgM antibodies more frequently compared with Platelia in groups II and III or than pre...
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
346
39,355
0
false
Platelia detected IgM antibodies from 21.4% of group II patients (upper or lower respiratory infection except pneumonia with infiltrations) and 23.5% of group III patients (acute exacerbation of asthma), and other 3 IgM EIAs detected IgM antibodies more frequently compared with Platelia in groups II and III or than pre...
[]
Platelia detected IgM antibodies from 21.4% of group II patients (upper or lower respiratory infection except pneumonia with infiltrations) and 23.5% of group III patients (acute exacerbation of asthma), and other 3 IgM EIAs detected IgM antibodies more frequently compared with Platelia in groups II and III or than pre...
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
Because our study was performed on 73 children within 2 winter-months for the purpose of comparison of methods, the possibility of M. pneumoniae epidemics and the small number of study participants could explain the higher positive rates.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
238
39,356
0
false
Because our study was performed on 73 children within 2 winter-months for the purpose of comparison of methods, the possibility of M. pneumoniae epidemics and the small number of study participants could explain the higher positive rates.
[]
Because our study was performed on 73 children within 2 winter-months for the purpose of comparison of methods, the possibility of M. pneumoniae epidemics and the small number of study participants could explain the higher positive rates.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
The positive or equivocal reactions of IgM EIAs in a patient with infectious mononucleosis suggested false positive activity due to heterophil antibodies.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
154
39,357
0
false
The positive or equivocal reactions of IgM EIAs in a patient with infectious mononucleosis suggested false positive activity due to heterophil antibodies.
[]
The positive or equivocal reactions of IgM EIAs in a patient with infectious mononucleosis suggested false positive activity due to heterophil antibodies.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
More specimens need to be evaluated for the heterophil antibody reactions to fully understand these findings.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
109
39,358
0
false
More specimens need to be evaluated for the heterophil antibody reactions to fully understand these findings.
[]
More specimens need to be evaluated for the heterophil antibody reactions to fully understand these findings.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
A patient with glomerulonephritis and a patient with HSP had a positive reaction in one or more IgM EIAs.
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
105
39,359
0
false
A patient with glomerulonephritis and a patient with HSP had a positive reaction in one or more IgM EIAs.
[]
A patient with glomerulonephritis and a patient with HSP had a positive reaction in one or more IgM EIAs.
true
true
true
true
true
6,785
0
DISCUSSION
1
1
[ "B1", "B8", "B8", "B9", "B8", "B10", "B11", "B12" ]
17,982,225
pmid-15489344|pmid-7667050|pmid-15489344|pmid-11871806|pmid-11871806|pmid-11303262|pmid-11871806|pmid-10325314|pmid-7416624|pmid-152413
These cases could not be discriminated from true M. pneumoniae infections; in fact, there have been many cases reported as glomerulonephritis and other systemic manifestations in patients with M. pneumoniae (11, 12).
[ "1", "8", "8", "9", "8", "10", "11", "12" ]
216
39,360
0
false
These cases could not be discriminated from true M. pneumoniae infections; in fact, there have been many cases reported as glomerulonephritis and other systemic manifestations in patients with M. pneumoniae.
[ "11, 12" ]
These cases could not be discriminated from true M. pneumoniae infections; in fact, there have been many cases reported as glomerulonephritis and other systemic manifestations in patients with M. pneumoniae.
true
true
true
true
true
6,785
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
The PA titer for the best sensitivity and specificity for the diagnosis of M. pneumoniae infections was controversial in previous reports.
[ "13", "14", "15", "15" ]
138
39,361
0
false
The PA titer for the best sensitivity and specificity for the diagnosis of M. pneumoniae infections was controversial in previous reports.
[]
The PA titer for the best sensitivity and specificity for the diagnosis of M. pneumoniae infections was controversial in previous reports.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
A comparison study of PA titer, culture, and PCR indicated a PA titer ≥1:160 had the greatest diagnostic power in a child with respiratory symptoms based on good receiver-operating characteristic areas under the curve (13).
[ "13", "14", "15", "15" ]
223
39,362
1
false
A comparison study of PA titer, culture, and PCR indicated a PA titer ≥1:160 had the greatest diagnostic power in a child with respiratory symptoms based on good receiver-operating characteristic areas under the curve.
[ "13" ]
A comparison study of PA titer, culture, and PCR indicated a PA titer ≥1:160 had the greatest diagnostic power in a child with respiratory symptoms based on good receiver-operating characteristic areas under the curve.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
Other investigators suggested a PA titer ≥1:640 (14, 15).
[ "13", "14", "15", "15" ]
57
39,363
0
false
Other investigators suggested a PA titer ≥1:640.
[ "14, 15" ]
Other investigators suggested a PA titer ≥1:640.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
Choi et al.
[ "13", "14", "15", "15" ]
11
39,364
0
false
Choi et al.
[]
Choi et al.
true
true
true
true
true
6,786
1
DISCUSSION
1
15
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
evaluated the mycoplasma antibody titer from 177 healthy children with the PA assay used in our study; 46.3% of healthy children were PA-positive, and their titers were 1:320 or less (15).
[ "13", "14", "15", "15" ]
188
39,365
1
false
evaluated the mycoplasma antibody titer from 177 healthy children with the PA assay used in our study; 46.3% of healthy children were PA-positive, and their titers were 1:320 or less.
[ "15" ]
evaluated the mycoplasma antibody titer from 177 healthy children with the PA assay used in our study; 46.3% of healthy children were PA-positive, and their titers were 1:320 or less.
false
true
true
true
false
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
In our series, Serodia MycoII showed high sensitivity presenting positive results in 83 of 94 specimens (91.2%) with the manufacturer's cutoff, 1:40.
[ "13", "14", "15", "15" ]
149
39,366
0
false
In our series, Serodia MycoII showed high sensitivity presenting positive results in 83 of 94 specimens (91.2%) with the manufacturer's cutoff, 1:40.
[]
In our series, Serodia MycoII showed high sensitivity presenting positive results in 83 of 94 specimens with the manufacturer's cutoff, 1:40.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
However, most of 25 specimens with PA titers ≤1:160 were negative for IgM antibodies with EIAs but positive for IgG antibodies.
[ "13", "14", "15", "15" ]
127
39,367
0
false
However, most of 25 specimens with PA titers ≤1:160 were negative for IgM antibodies with EIAs but positive for IgG antibodies.
[]
However, most of 25 specimens with PA titers ≤1:160 were negative for IgM antibodies with EIAs but positive for IgG antibodies.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
We evaluated the agreements of EIAs with each titer of PA and 3 of 4 IgM EIAs had the best concordance with PA titer 1:320.
[ "13", "14", "15", "15" ]
123
39,368
0
false
We evaluated the agreements of EIAs with each titer of PA and 3 of 4 IgM EIAs had the best concordance with PA titer 1:320.
[]
We evaluated the agreements of EIAs with each titer of PA and 3 of 4 IgM EIAs had the best concordance with PA titer 1:320.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
They showed good concordance rates, 82.4% to 92.3% and their quantitative results were significantly correlated.
[ "13", "14", "15", "15" ]
112
39,369
0
false
They showed good concordance rates, 82.4% to 92.3% and their quantitative results were significantly correlated.
[]
They showed good concordance rates, 82.4% to 92.3% and their quantitative results were significantly correlated.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
However, IgG EIAs demonstrated a lower concordance and no significant correlations with PA titers.
[ "13", "14", "15", "15" ]
98
39,370
0
false
However, IgG EIAs demonstrated a lower concordance and no significant correlations with PA titers.
[]
However, IgG EIAs demonstrated a lower concordance and no significant correlations with PA titers.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
These observations supported the manufacturer's claim that Serodia MycoII detects exclusively M. pneumoniae-specific IgM.
[ "13", "14", "15", "15" ]
121
39,371
0
false
These observations supported the manufacturer's claim that Serodia MycoII detects exclusively M. pneumoniae-specific IgM.
[]
These observations supported the manufacturer's claim that Serodia MycoII detects exclusively M. pneumoniae-specific IgM.
true
true
true
true
true
6,786
1
DISCUSSION
1
13
[ "B13", "B14", "B15", "B15" ]
17,982,225
pmid-1281781|pmid-7510308|NA|pmid-10654958|NA|NA
However, some cases suggested that IgG antibodies resulted PA-positive reactions, especially at low PA titers.
[ "13", "14", "15", "15" ]
110
39,372
0
false
However, some cases suggested that IgG antibodies resulted PA-positive reactions, especially at low PA titers.
[]
However, some cases suggested that IgG antibodies resulted PA-positive reactions, especially at low PA titers.
true
true
true
true
true
6,786
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
A few specimens in our study showed IgM negativity in spite of high PA titers (≥1:1,280) and similar findings were observed in previous reports (7).
[ "7", "16", "17", "17", "18" ]
148
39,373
1
false
A few specimens in our study showed IgM negativity in spite of high PA titers (≥1:1,280) and similar findings were observed in previous reports.
[ "7" ]
A few specimens in our study showed IgM negativity in spite of high PA titers (≥1:1,280) and similar findings were observed in previous reports.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Our cases showed high IgG titers in the same specimen or positive conversions of IgM antibodies in follow-up specimens.
[ "7", "16", "17", "17", "18" ]
119
39,374
0
false
Our cases showed high IgG titers in the same specimen or positive conversions of IgM antibodies in follow-up specimens.
[]
Our cases showed high IgG titers in the same specimen or positive conversions of IgM antibodies in follow-up specimens.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Yoon et al.
[ "7", "16", "17", "17", "18" ]
11
39,375
0
false
Yoon et al.
[]
Yoon et al.
true
true
true
true
true
6,787
2
DISCUSSION
1
16
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
reported positive rates of M. pneumoniae antibodies reached a peak from 7th to 9th day and went down after 16th day (16).
[ "7", "16", "17", "17", "18" ]
121
39,376
1
false
reported positive rates of M. pneumoniae antibodies reached a peak from 7th to 9th day and went down after 16th day.
[ "16" ]
reported positive rates of M. pneumoniae antibodies reached a peak from 7th to 9th day and went down after 16th day.
false
true
true
true
false
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Some specimens in our series were obtained 10 days or more after the onset of symptoms and follow-up specimens at an interval less than 7 days.
[ "7", "16", "17", "17", "18" ]
143
39,377
0
false
Some specimens in our series were obtained 10 days or more after the onset of symptoms and follow-up specimens at an interval less than 7 days.
[]
Some specimens in our series were obtained 10 days or more after the onset of symptoms and follow-up specimens at an interval less than 7 days.
true
true
true
true
true
6,787
2
DISCUSSION
1
17
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
It could not be ruled out that late sampling times decreased the IgM EIA positive rates and increased the IgG EIA positive rates in PA-positive specimens (17).
[ "7", "16", "17", "17", "18" ]
159
39,378
1
false
It could not be ruled out that late sampling times decreased the IgM EIA positive rates and increased the IgG EIA positive rates in PA-positive specimens.
[ "17" ]
It could not be ruled out that late sampling times decreased the IgM EIA positive rates and increased the IgG EIA positive rates in PA-positive specimens.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
The first blood specimen within 10 days of the onset of illness and convalescent serum at intervals of 7 to 10 days are important for demonstrating a significant rise in antibody titers (17, 18).
[ "7", "16", "17", "17", "18" ]
195
39,379
0
false
The first blood specimen within 10 days of the onset of illness and convalescent serum at intervals of 7 to 10 days are important for demonstrating a significant rise in antibody titers.
[ "17, 18" ]
The first blood specimen within 10 days of the onset of illness and convalescent serum at intervals of 7 to 10 days are important for demonstrating a significant rise in antibody titers.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
For Platelia IgG EIA, the manufacturer's guidelines indicated that high IgG values (>40 AU/mL) could be interpreted as a current infection and it compensated for the relatively low sensitivity of the Platelia IgM assay.
[ "7", "16", "17", "17", "18" ]
219
39,380
0
false
For Platelia IgG EIA, the manufacturer's guidelines indicated that high IgG values (>40 AU/mL) could be interpreted as a current infection and it compensated for the relatively low sensitivity of the Platelia IgM assay.
[]
For Platelia IgG EIA, the manufacturer's guidelines indicated that high IgG values (>40 AU/mL) could be interpreted as a current infection and it compensated for the relatively low sensitivity of the Platelia IgM assay.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Use of EIAs enabled the simultaneous testing of specific IgG and IgM antibodies, and it was helpful for assessing some IgM negative- and IgG positive cases as past infections, especially for the patients with low PA titers.
[ "7", "16", "17", "17", "18" ]
223
39,381
0
false
Use of EIAs enabled the simultaneous testing of specific IgG and IgM antibodies, and it was helpful for assessing some IgM negative- and IgG positive cases as past infections, especially for the patients with low PA titers.
[]
Use of EIAs enabled the simultaneous testing of specific IgG and IgM antibodies, and it was helpful for assessing some IgM negative- and IgG positive cases as past infections, especially for the patients with low PA titers.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
However, in the clinical situation of a single negative IgM EIA result, another specimen for paired evaluation was supposed to be necessary to establish the diagnosis of current infection of M. pneumoniae.
[ "7", "16", "17", "17", "18" ]
205
39,382
0
false
However, in the clinical situation of a single negative IgM EIA result, another specimen for paired evaluation was supposed to be necessary to establish the diagnosis of current infection of M. pneumoniae.
[]
However, in the clinical situation of a single negative IgM EIA result, another specimen for paired evaluation was supposed to be necessary to establish the diagnosis of current infection of M. pneumoniae.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
This comparison study included 34 paired sera from 16 patients, and two of them showed positive conversions of IgG antibodies.
[ "7", "16", "17", "17", "18" ]
126
39,383
0
false
This comparison study included 34 paired sera from 16 patients, and two of them showed positive conversions of IgG antibodies.
[]
This comparison study included 34 paired sera from 16 patients, and two of them showed positive conversions of IgG antibodies.
true
true
true
true
true
6,787
2
DISCUSSION
1
7
[ "B7", "B16", "B17", "B17", "B18" ]
17,982,225
pmid-15489344|pmid-8353251|pmid-15489344|pmid-2108192|pmid-2108192|NA|pmid-12667235|pmid-12667235|pmid-16100441
Further studies with large numbers of paired sera might show the possibility of IgG EIAs as a supplementary role for confirming current infections of M. pneumoniae.
[ "7", "16", "17", "17", "18" ]
164
39,384
0
false
Further studies with large numbers of paired sera might show the possibility of IgG EIAs as a supplementary role for confirming current infections of M. pneumoniae.
[]
Further studies with large numbers of paired sera might show the possibility of IgG EIAs as a supplementary role for confirming current infections of M. pneumoniae.
true
true
true
true
true
6,787
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
Nineteen patients (20.9%) had IgA antibodies with one or two available IgA EIA kits, and all of them had positive IgM results suggesting the specificities of IgA EIAs for current M. pneumoniae infections.
[ "19" ]
204
39,385
0
false
Nineteen patients (20.9%) had IgA antibodies with one or two available IgA EIA kits, and all of them had positive IgM results suggesting the specificities of IgA EIAs for current M. pneumoniae infections.
[]
Nineteen patients had IgA antibodies with one or two available IgA EIA kits, and all of them had positive IgM results suggesting the specificities of IgA EIAs for current M. pneumoniae infections.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
However, their clinical usefulness was hampered by low positive rates in our pediatric patients.
[ "19" ]
96
39,386
0
false
However, their clinical usefulness was hampered by low positive rates in our pediatric patients.
[]
However, their clinical usefulness was hampered by low positive rates in our pediatric patients.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
Granstrom et al.
[ "19" ]
16
39,387
0
false
Granstrom et al.
[]
Granstrom et al.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
reported that IgA EIA was useful for early diagnosis of acute infection in adults due to its earlier response compared to IgM and occasional lack of IgM formation in adults (19).
[ "19" ]
178
39,388
1
false
reported that IgA EIA was useful for early diagnosis of acute infection in adults due to its earlier response compared to IgM and occasional lack of IgM formation in adults.
[ "19" ]
reported that IgA EIA was useful for early diagnosis of acute infection in adults due to its earlier response compared to IgM and occasional lack of IgM formation in adults.
false
true
true
true
false
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
They reported that specific IgA antibodies developed more regularly and more rapidly than IgM antibodies, and IgA titers also started to decrease earlier than IgM antibodies or the late-peaking IgG responses.
[ "19" ]
208
39,389
0
false
They reported that specific IgA antibodies developed more regularly and more rapidly than IgM antibodies, and IgA titers also started to decrease earlier than IgM antibodies or the late-peaking IgG responses.
[]
They reported that specific IgA antibodies developed more regularly and more rapidly than IgM antibodies, and IgA titers also started to decrease earlier than IgM antibodies or the late-peaking IgG responses.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
All of our patients with positive IgA results had high IgM titers, suggesting early phases of infections.
[ "19" ]
105
39,390
0
false
All of our patients with positive IgA results had high IgM titers, suggesting early phases of infections.
[]
All of our patients with positive IgA results had high IgM titers, suggesting early phases of infections.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
Late sampling was considered as a possible cause of low positive rates of IgA antibodies in our patients.
[ "19" ]
105
39,391
0
false
Late sampling was considered as a possible cause of low positive rates of IgA antibodies in our patients.
[]
Late sampling was considered as a possible cause of low positive rates of IgA antibodies in our patients.
true
true
true
true
true
6,788
3
DISCUSSION
1
19
[ "B19" ]
17,982,225
pmid-8151681
Presentations in post-acute stages of infections at our tertiary-care hospital was thought to have caused missing the early phase to obtain IgA-positive result.
[ "19" ]
160
39,392
0
false
Presentations in post-acute stages of infections at our tertiary-care hospital was thought to have caused missing the early phase to obtain IgA-positive result.
[]
Presentations in post-acute stages of infections at our tertiary-care hospital was thought to have caused missing the early phase to obtain IgA-positive result.
true
true
true
true
true
6,788
4
DISCUSSION
0
null
null
17,982,225
null
An assay format other than serologic methods was not performed for the determination of the specificity and sensitivity.
null
120
39,393
0
false
null
null
An assay format other than serologic methods was not performed for the determination of the specificity and sensitivity.
true
true
true
true
true
6,789
4
DISCUSSION
0
null
null
17,982,225
null
Even though there is no reference method for the diagnosis of M. pneumoniae infection, a study with a different method, such as PCR or culture, would provide more informative data.
null
180
39,394
0
false
null
null
Even though there is no reference method for the diagnosis of M. pneumoniae infection, a study with a different method, such as PCR or culture, would provide more informative data.
true
true
true
true
true
6,789
5
DISCUSSION
0
null
null
17,982,225
null
In conclusion, IgM EIAs for the detection of M. pneumoniae infection showed good agreements with the PA assay, and their quantitative results were well correlated.
null
163
39,395
0
false
null
null
In conclusion, IgM EIAs for the detection of M. pneumoniae infection showed good agreements with the PA assay, and their quantitative results were well correlated.
true
true
true
true
true
6,790
5
DISCUSSION
0
null
null
17,982,225
null
Confirmation of M. pneumoniae infection in a case with negative IgM antibodies required a serial sampling with convalescent serum.
null
130
39,396
0
false
null
null
Confirmation of M. pneumoniae infection in a case with negative IgM antibodies required a serial sampling with convalescent serum.
true
true
true
true
true
6,790
0
INTRODUCTION
1
1
[ "B1" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
Acute respiratory viral infections are a major cause of morbidity in pediatric patients.1 Although they are most often self-limited and confined to the upper respiratory tract, they lead to a substantial number of upper or lower respiratory tract complications.
[ "1" ]
261
39,397
0
false
Acute respiratory viral infections are a major cause of morbidity in pediatric patients.1 Although they are most often self-limited and confined to the upper respiratory tract, they lead to a substantial number of upper or lower respiratory tract complications.
[]
Acute respiratory viral infections are a major cause of morbidity in pediatric patients.1 Although they are most often self-limited and confined to the upper respiratory tract, they lead to a substantial number of upper or lower respiratory tract complications.
true
true
true
true
true
6,791
0
INTRODUCTION
1
1
[ "B1" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
Therefore, accurate and rapid diagnosis of respiratory virus infection is essential for the initiation of early treatment and the prevention of viral spread.
[ "1" ]
157
39,398
0
false
Therefore, accurate and rapid diagnosis of respiratory virus infection is essential for the initiation of early treatment and the prevention of viral spread.
[]
Therefore, accurate and rapid diagnosis of respiratory virus infection is essential for the initiation of early treatment and the prevention of viral spread.
true
true
true
true
true
6,791
1
INTRODUCTION
1
2
[ "B2", "B3", "B4", "B5", "B6", "B8" ]
20,635,453
pmid-9508315|pmid-8748290|pmid-11593321|pmid-10868137|pmid-12791735|pmid-16473836|pmid-15096568|pmid-9854054|pmid-11473991|pmid-11325976|pmid-9636869|pmid-16886150
Several studies evaluating polymerase chain reaction (PCR)-based methods for the detection and typing of respiratory viruses were reported.2,3 The adenovirus (AdV), influenza virus (IFV), parainfluenza virus (PIFV), and respiratory syncytial virus (RSV) have been identified as significant pathogens in community-acquire...
[ "2", "3", "4", "5", "6", "8" ]
502
39,399
0
false
Several studies evaluating polymerase chain reaction (PCR)-based methods for the detection and typing of respiratory viruses were reported.2,3 The adenovirus (AdV), influenza virus (IFV), parainfluenza virus (PIFV), and respiratory syncytial virus (RSV) have been identified as significant pathogens in community-acquire...
[]
Several studies evaluating polymerase chain reaction (PCR)-based methods for the detection and typing of respiratory viruses were reported.2,3 The adenovirus (AdV), influenza virus (IFV), parainfluenza virus (PIFV), and respiratory syncytial virus (RSV) have been identified as significant pathogens in community-acquire...
true
true
false
true
false
6,792
2
INTRODUCTION
0
null
null
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
The aim of this study is to evaluate and suggest clinical usefulness of two kinds of multiplex PCR for identifying causative viruses in pediatric viral pneumonia, which is the most severe lower respiratory infection in children.
null
228
39,400
0
false
null
null
The aim of this study is to evaluate and suggest clinical usefulness of two kinds of multiplex PCR for identifying causative viruses in pediatric viral pneumonia, which is the most severe lower respiratory infection in children.
true
true
true
true
true
6,793
0
DISCUSSION
1
6
[ "B6", "B8" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
Rapid and accurate identification of causative agents in viral pneumonia of pediatric patients is essential to prevent disease propagation.
[ "6", "8" ]
139
39,401
0
false
Rapid and accurate identification of causative agents in viral pneumonia of pediatric patients is essential to prevent disease propagation.
[]
Rapid and accurate identification of causative agents in viral pneumonia of pediatric patients is essential to prevent disease propagation.
true
true
true
true
true
6,794
0
DISCUSSION
1
6
[ "B6", "B8" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
It is also helpful for early initiation of proper management.
[ "6", "8" ]
61
39,402
0
false
It is also helpful for early initiation of proper management.
[]
It is also helpful for early initiation of proper management.
true
true
true
true
true
6,794
0
DISCUSSION
1
6
[ "B6", "B8" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
An early start of proper anti-viral management can reduce unnecessary overuse of antibacterial agents.
[ "6", "8" ]
102
39,403
0
false
An early start of proper anti-viral management can reduce unnecessary overuse of antibacterial agents.
[]
An early start of proper anti-viral management can reduce unnecessary overuse of antibacterial agents.
true
true
true
true
true
6,794
0
DISCUSSION
1
6
[ "B6", "B8" ]
20,635,453
pmid-18174876|pmid-12791735|pmid-16473836
In addition, some respiratory viruses, including IFV, EnV, and AdV, may now benefit from specific antiviral treatment.6-8 So, we designed and performed this study to evaluate two kinds of multiplex PCR kits and a commercial shell vial culture method for their clinical efficacy with prospectively collected samples of pe...
[ "6", "8" ]
337
39,404
0
false
In addition, some respiratory viruses, including IFV, EnV, and AdV, may now benefit from specific antiviral treatment.6-8 So, we designed and performed this study to evaluate two kinds of multiplex PCR kits and a commercial shell vial culture method for their clinical efficacy with prospectively collected samples of pe...
[]
In addition, some respiratory viruses, including IFV, EnV, and AdV, may now benefit from specific antiviral treatment.6-8 So, we designed and performed this study to evaluate two kinds of multiplex PCR kits and a commercial shell vial culture method for their clinical efficacy with prospectively collected samples of pe...
true
true
true
true
true
6,794
1
DISCUSSION
1
9
[ "B9", "B10", "B12", "B11", "B13", "B14" ]
20,635,453
pmid-9508315|pmid-8748290|pmid-11593321|pmid-10868137|pmid-12791735|pmid-16473836|pmid-15096568|pmid-9854054|pmid-11473991|pmid-11325976|pmid-9636869|pmid-16886150
Until now, virus isolation by a cell culture and a direct immunofluorescent antigen staining assay has been the most commonly used method for identifying respiratory viruses.9 An enzyme immunoassay may be quicker but it is less sensitive.
[ "9", "10", "12", "11", "13", "14" ]
238
39,405
0
false
Until now, virus isolation by a cell culture and a direct immunofluorescent antigen staining assay has been the most commonly used method for identifying respiratory viruses.9 An enzyme immunoassay may be quicker but it is less sensitive.
[]
Until now, virus isolation by a cell culture and a direct immunofluorescent antigen staining assay has been the most commonly used method for identifying respiratory viruses.9 An enzyme immunoassay may be quicker but it is less sensitive.
true
true
true
true
true
6,795
1
DISCUSSION
1
9
[ "B9", "B10", "B12", "B11", "B13", "B14" ]
20,635,453
pmid-9508315|pmid-8748290|pmid-11593321|pmid-10868137|pmid-12791735|pmid-16473836|pmid-15096568|pmid-9854054|pmid-11473991|pmid-11325976|pmid-9636869|pmid-16886150
These conventional methods may be affected by specimen quality, virus type, and technical skill.10-12 The virus culture is still considered the gold standard for respiratory virus detection, but it has limitations in turnaround time, specimen transport, and storage conditions in maintaining the infectivity of the virus...
[ "9", "10", "12", "11", "13", "14" ]
551
39,406
0
false
These conventional methods may be affected by specimen quality, virus type, and technical skill.10-12 The virus culture is still considered the gold standard for respiratory virus detection, but it has limitations in turnaround time, specimen transport, and storage conditions in maintaining the infectivity of the virus...
[]
These conventional methods may be affected by specimen quality, virus type, and technical skill.10-12 The virus culture is still considered the gold standard for respiratory virus detection, but it has limitations in turnaround time, specimen transport, and storage conditions in maintaining the infectivity of the virus...
true
true
true
true
true
6,795
2
DISCUSSION
1
9
[ "B9", "B15", "B17", "B18" ]
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
Recently, virus identification by immunostaing after shell vial culture is the most widely accepted laboratory standard method of virus testing.
[ "9", "15", "17", "18" ]
144
39,407
0
false
Recently, virus identification by immunostaing after shell vial culture is the most widely accepted laboratory standard method of virus testing.
[]
Recently, virus identification by immunostaing after shell vial culture is the most widely accepted laboratory standard method of virus testing.
true
true
true
true
true
6,796
2
DISCUSSION
1
9
[ "B9", "B15", "B17", "B18" ]
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
But, this method is still not easy for routine testing in clinical laboratories.
[ "9", "15", "17", "18" ]
80
39,408
0
false
But, this method is still not easy for routine testing in clinical laboratories.
[]
But, this method is still not easy for routine testing in clinical laboratories.
true
true
true
true
true
6,796
2
DISCUSSION
1
9
[ "B9", "B15", "B17", "B18" ]
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
The nucleic acid amplification method including multiplex PCR is a powerful alternative, but it has some limitations of false positivity and false negativity.
[ "9", "15", "17", "18" ]
158
39,409
0
false
The nucleic acid amplification method including multiplex PCR is a powerful alternative, but it has some limitations of false positivity and false negativity.
[]
The nucleic acid amplification method including multiplex PCR is a powerful alternative, but it has some limitations of false positivity and false negativity.
true
true
true
true
true
6,796
2
DISCUSSION
1
9
[ "B9", "B15", "B17", "B18" ]
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
The nucleic acid amplification test is faster than the culture method and has been reported to be more sensitive9,15-17 and can be automated these days.
[ "9", "15", "17", "18" ]
152
39,410
0
false
The nucleic acid amplification test is faster than the culture method and has been reported to be more sensitive9,15-17 and can be automated these days.
[]
The nucleic acid amplification test is faster than the culture method and has been reported to be more sensitive9,15-17 and can be automated these days.
true
true
true
true
true
6,796
2
DISCUSSION
1
9
[ "B9", "B15", "B17", "B18" ]
20,635,453
pmid-15096568|pmid-11740705|pmid-14767825|pmid-14730267
In addition, there are advantages in detecting some viruses which grow poorly in cell cultures such as HMPV.18
[ "9", "15", "17", "18" ]
110
39,411
0
false
In addition, there are advantages in detecting some viruses which grow poorly in cell cultures such as HMPV.18
[]
In addition, there are advantages in detecting some viruses which grow poorly in cell cultures such as HMPV.18
true
true
false
true
false
6,796
3
DISCUSSION
1
19
[ "B19" ]
20,635,453
NA
A Korean national survey19 of respiratory virus testing was performed and thirty-one clinical laboratories responded that they provided respiratory virus testing for clinical diagnosis in Korea.
[ "19" ]
194
39,412
0
false
A Korean national survey19 of respiratory virus testing was performed and thirty-one clinical laboratories responded that they provided respiratory virus testing for clinical diagnosis in Korea.
[]
A Korean national survey19 of respiratory virus testing was performed and thirty-one clinical laboratories responded that they provided respiratory virus testing for clinical diagnosis in Korea.
true
true
true
true
true
6,797
3
DISCUSSION
1
19
[ "B19" ]
20,635,453
NA
Among the responders, PCR and/or culture were most widely adopted, in 42% of the institutes, rapid immunochromatographic method 29%, immunofluorescent antigen assay 23%, and enzyme immunoassay 7%.
[ "19" ]
196
39,413
0
false
Among the responders, PCR and/or culture were most widely adopted, in 42% of the institutes, rapid immunochromatographic method 29%, immunofluorescent antigen assay 23%, and enzyme immunoassay 7%.
[]
Among the responders, PCR and/or culture were most widely adopted, in 42% of the institutes, rapid immunochromatographic method 29%, immunofluorescent antigen assay 23%, and enzyme immunoassay 7%.
true
true
true
true
true
6,797
4
DISCUSSION
1
9
[ "B9", "B10", "B14" ]
20,635,453
pmid-15096568|pmid-9854054|pmid-16886150
We focused on the four major respiratory viruses of AdV, IFV, PIFV, and RSV.
[ "9", "10", "14" ]
76
39,414
0
false
We focused on the four major respiratory viruses of AdV, IFV, PIFV, and RSV.
[]
We focused on the four major respiratory viruses of AdV, IFV, PIFV, and RSV.
true
true
true
true
true
6,798
4
DISCUSSION
1
9
[ "B9", "B10", "B14" ]
20,635,453
pmid-15096568|pmid-9854054|pmid-16886150
The exact concordance rate between the two kinds of multiplex PCR and R-Mix viral culture was 48.5% (50/103).
[ "9", "10", "14" ]
109
39,415
0
false
The exact concordance rate between the two kinds of multiplex PCR and R-Mix viral culture was 48.5%.
[ "50/103" ]
The exact concordance rate between the two kinds of multiplex PCR and R-Mix viral culture was 48.5%.
true
true
true
true
true
6,798