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PMC2245969_F1_17721.jpg
What is the principal component of this image?
Immunolocalization of CYP27B1 and VDR in placental chorionic villi. Placental sections were incubated with specific antibodies in order to localize important components of the vitamin D endocrine system. CYP27B1 protein was located in the syncytiotrophoblast layer (A). The use of anti N-terminus VDR specific antibody d...
PMC2246013_pone-0001684-g003_17730.jpg
Describe the main subject of this image.
Enhanced NMDAR function in cerebellar granule cells of tg mice.A–F. Representative Ca2+ imaging microphotos from before the NMDA (0.1 µM together with glycine 10 µM) application (A and D), the maximal [Ca2+]I responses (B and E), and returned to the basal level (C and F) in control cell (A–C) and tg cell (D–F), respect...
PMC2246013_pone-0001684-g003_17735.jpg
What is shown in this image?
Enhanced NMDAR function in cerebellar granule cells of tg mice.A–F. Representative Ca2+ imaging microphotos from before the NMDA (0.1 µM together with glycine 10 µM) application (A and D), the maximal [Ca2+]I responses (B and E), and returned to the basal level (C and F) in control cell (A–C) and tg cell (D–F), respect...
PMC2246013_pone-0001684-g004_17723.jpg
What object or scene is depicted here?
Morphological changes in the cerebellum of tg mice.A and B. Nissl straining of sagital sections from control (A) and tg (B) mice. No observable difference, either in general morphology of granule cells or cell number in granule cell layer, was found between them. C and D. Immunohistological staining with DK-28 (Sigma)....
PMC2246013_pone-0001684-g004_17727.jpg
What does this image primarily show?
Morphological changes in the cerebellum of tg mice.A and B. Nissl straining of sagital sections from control (A) and tg (B) mice. No observable difference, either in general morphology of granule cells or cell number in granule cell layer, was found between them. C and D. Immunohistological staining with DK-28 (Sigma)....
PMC2246013_pone-0001684-g004_17725.jpg
What's the most prominent thing you notice in this picture?
Morphological changes in the cerebellum of tg mice.A and B. Nissl straining of sagital sections from control (A) and tg (B) mice. No observable difference, either in general morphology of granule cells or cell number in granule cell layer, was found between them. C and D. Immunohistological staining with DK-28 (Sigma)....
PMC2246013_pone-0001684-g004_17728.jpg
What object or scene is depicted here?
Morphological changes in the cerebellum of tg mice.A and B. Nissl straining of sagital sections from control (A) and tg (B) mice. No observable difference, either in general morphology of granule cells or cell number in granule cell layer, was found between them. C and D. Immunohistological staining with DK-28 (Sigma)....
PMC2246013_pone-0001684-g004_17724.jpg
What key item or scene is captured in this photo?
Morphological changes in the cerebellum of tg mice.A and B. Nissl straining of sagital sections from control (A) and tg (B) mice. No observable difference, either in general morphology of granule cells or cell number in granule cell layer, was found between them. C and D. Immunohistological staining with DK-28 (Sigma)....
PMC2246016_pone-0001676-g002_17738.jpg
What is shown in this image?
Tracks of A, control bats B, bats pulsed parallel to the biasing field and C, bats pulsed antiparallel to the biasing field.Vector arrows represent the vanishing bearing and distance. Numbers identify the track and the vanishing bearing associated with it.
PMC2246016_pone-0001676-g002_17737.jpg
What does this image primarily show?
Tracks of A, control bats B, bats pulsed parallel to the biasing field and C, bats pulsed antiparallel to the biasing field.Vector arrows represent the vanishing bearing and distance. Numbers identify the track and the vanishing bearing associated with it.
PMC2246019_pone-0001685-g005_17741.jpg
What is the main focus of this visual representation?
(A) Survival of mice whose airways had been inoculated at day 0 with 7.5×106 CFU of P. aeruginosa TBCF10839 (closed square) or of the isogenic transposon mutants P. aeruginosa TBCF10839 Tn5::PA4640(mqoB) (closed circle), P. aeruginosa TBCF10839 Tn5::PA3194(edd) (closed triangle) or P. aeruginosa TBCF10839 Tn5::PA4954(m...
PMC2246019_pone-0001685-g005_17739.jpg
What stands out most in this visual?
(A) Survival of mice whose airways had been inoculated at day 0 with 7.5×106 CFU of P. aeruginosa TBCF10839 (closed square) or of the isogenic transposon mutants P. aeruginosa TBCF10839 Tn5::PA4640(mqoB) (closed circle), P. aeruginosa TBCF10839 Tn5::PA3194(edd) (closed triangle) or P. aeruginosa TBCF10839 Tn5::PA4954(m...
PMC2246019_pone-0001685-g005_17745.jpg
What key item or scene is captured in this photo?
(A) Survival of mice whose airways had been inoculated at day 0 with 7.5×106 CFU of P. aeruginosa TBCF10839 (closed square) or of the isogenic transposon mutants P. aeruginosa TBCF10839 Tn5::PA4640(mqoB) (closed circle), P. aeruginosa TBCF10839 Tn5::PA3194(edd) (closed triangle) or P. aeruginosa TBCF10839 Tn5::PA4954(m...
PMC2246019_pone-0001685-g005_17744.jpg
What is the central feature of this picture?
(A) Survival of mice whose airways had been inoculated at day 0 with 7.5×106 CFU of P. aeruginosa TBCF10839 (closed square) or of the isogenic transposon mutants P. aeruginosa TBCF10839 Tn5::PA4640(mqoB) (closed circle), P. aeruginosa TBCF10839 Tn5::PA3194(edd) (closed triangle) or P. aeruginosa TBCF10839 Tn5::PA4954(m...
PMC2246098_F2_17746.jpg
What object or scene is depicted here?
T2-weighted MR scan of a patient with unilateral anophthalmia. Note the presence of amorphous tissue and structures resembling extraocular muscles within the anophthalmic right orbit. The right optic nerve/chiasm junction appears attenuated rather than absent suggesting possible residual optic nerve neural tissue.
PMC2246125_F4_17753.jpg
What is the main focus of this visual representation?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17748.jpg
What is being portrayed in this visual content?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17755.jpg
What is the main focus of this visual representation?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17751.jpg
What is the principal component of this image?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17750.jpg
What is the principal component of this image?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17749.jpg
What is shown in this image?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246125_F4_17752.jpg
What is the dominant medical problem in this image?
Human 14-3-3γ induces increased cell proliferation in the morphogenetic furrow region of eye imaginal discs. Third instar larvae were collected and processed for incorporation of BrdU as described previously and the imaginal discs dissected and examined using confocal microscopy. GFP expression (GFP) is shown in green ...
PMC2246129_F3_17763.jpg
What is the focal point of this photograph?
Quantification of focal adhesion localization. A) CHO-K1 cells were transfected with the empty EGFP vector or GFP N-terminally tagged versions of wild type or FAK mutants. Stably expressing populations were selected and lysed. Twenty-five μg of lysate was immunoblotted to examine FAK expression. Endogenous FAK and GFP-...
PMC2246129_F3_17757.jpg
What can you see in this picture?
Quantification of focal adhesion localization. A) CHO-K1 cells were transfected with the empty EGFP vector or GFP N-terminally tagged versions of wild type or FAK mutants. Stably expressing populations were selected and lysed. Twenty-five μg of lysate was immunoblotted to examine FAK expression. Endogenous FAK and GFP-...
PMC2246129_F3_17762.jpg
What stands out most in this visual?
Quantification of focal adhesion localization. A) CHO-K1 cells were transfected with the empty EGFP vector or GFP N-terminally tagged versions of wild type or FAK mutants. Stably expressing populations were selected and lysed. Twenty-five μg of lysate was immunoblotted to examine FAK expression. Endogenous FAK and GFP-...
PMC2246129_F3_17758.jpg
What is the main focus of this visual representation?
Quantification of focal adhesion localization. A) CHO-K1 cells were transfected with the empty EGFP vector or GFP N-terminally tagged versions of wild type or FAK mutants. Stably expressing populations were selected and lysed. Twenty-five μg of lysate was immunoblotted to examine FAK expression. Endogenous FAK and GFP-...
PMC2246133_F1_17764.jpg
What object or scene is depicted here?
Computed tomography of the neck revealed the left thyroid tumor (arrow).
PMC2246133_F1_17765.jpg
What is being portrayed in this visual content?
Computed tomography of the neck revealed the left thyroid tumor (arrow).
PMC2246133_F3_17767.jpg
Describe the main subject of this image.
A. Immunohistochemical staining of the metastatic carcinoma was positive for alpha-fetoprotein (arrow). B. Negative control staining picture.
PMC2246133_F3_17766.jpg
What key item or scene is captured in this photo?
A. Immunohistochemical staining of the metastatic carcinoma was positive for alpha-fetoprotein (arrow). B. Negative control staining picture.
PMC2246138_F1_17768.jpg
What object or scene is depicted here?
Preoperative PET maximum intensity projection (A) and preoperative cross sectional fused PET/CT images (B) of a patient with recurrent metastatic melanoma to the left thigh. The preoperative PET/CT scan revealed three hypermetabolic foci within the left thigh.
PMC2246138_F3_17772.jpg
What stands out most in this visual?
Digital photograph of the three surgical specimens resected from the left thigh (A). Three dimensional CT reconstruction alone of the three surgical specimens from the left thigh (B). Three dimensional CT reconstruction of the three surgical specimens from the left thigh fused with PET activity (C). Cross sectional spe...
PMC2246138_F3_17774.jpg
Describe the main subject of this image.
Digital photograph of the three surgical specimens resected from the left thigh (A). Three dimensional CT reconstruction alone of the three surgical specimens from the left thigh (B). Three dimensional CT reconstruction of the three surgical specimens from the left thigh fused with PET activity (C). Cross sectional spe...
PMC2246138_F3_17775.jpg
Can you identify the primary element in this image?
Digital photograph of the three surgical specimens resected from the left thigh (A). Three dimensional CT reconstruction alone of the three surgical specimens from the left thigh (B). Three dimensional CT reconstruction of the three surgical specimens from the left thigh fused with PET activity (C). Cross sectional spe...
PMC2246138_F4_17771.jpg
What key item or scene is captured in this photo?
Preoperative PET maximum intensity projection in the anterior projection view (A) and postoperative PET maximum intensity projection in the anterior projection view (B). The postoperative PET/CT scan revealed verification of resection of hypermetabolic foci previously noted on the preoperative scan.
PMC2246147_F2_17780.jpg
What does this image primarily show?
Preoperative anteroposterior radiograph of the spine shows a left thoracolumbar scoliosis extending from T10 to L2 and measuring 50°.
PMC2246147_F2_17779.jpg
What is shown in this image?
Preoperative anteroposterior radiograph of the spine shows a left thoracolumbar scoliosis extending from T10 to L2 and measuring 50°.
PMC2246147_F2_17778.jpg
Describe the main subject of this image.
Preoperative anteroposterior radiograph of the spine shows a left thoracolumbar scoliosis extending from T10 to L2 and measuring 50°.
PMC2246207_F2_17782.jpg
What can you see in this picture?
Model simulations of arterial oxygen saturation and arterial oxygen partial pressure/inspired oxygen fraction ratio. (a) Inspired oxygen fraction (FiO2) versus arterial oxygen saturation (SaO2). (b) FiO2 versus the partial pressure of oxygen in arterial blood (PaO2)/FiO2 ratio. Simulations performed using shunt = 0–30%...
PMC2246234_F1_17787.jpg
What object or scene is depicted here?
Carotid intima media thickness in rheumatoid arthritis patients compared with matched healthy control individuals. The carotid intima media thickness (IMT) is increased in rheumatoid arthritis (RA) patients compared with healthy control individuals matched for age, sex and cardiovascular risk factors. Representative ca...
PMC2246234_F1_17788.jpg
What is the dominant medical problem in this image?
Carotid intima media thickness in rheumatoid arthritis patients compared with matched healthy control individuals. The carotid intima media thickness (IMT) is increased in rheumatoid arthritis (RA) patients compared with healthy control individuals matched for age, sex and cardiovascular risk factors. Representative ca...
PMC2246234_F1_17783.jpg
What does this image primarily show?
Carotid intima media thickness in rheumatoid arthritis patients compared with matched healthy control individuals. The carotid intima media thickness (IMT) is increased in rheumatoid arthritis (RA) patients compared with healthy control individuals matched for age, sex and cardiovascular risk factors. Representative ca...
PMC2246234_F1_17786.jpg
What is the central feature of this picture?
Carotid intima media thickness in rheumatoid arthritis patients compared with matched healthy control individuals. The carotid intima media thickness (IMT) is increased in rheumatoid arthritis (RA) patients compared with healthy control individuals matched for age, sex and cardiovascular risk factors. Representative ca...
PMC2246234_F1_17784.jpg
What is the central feature of this picture?
Carotid intima media thickness in rheumatoid arthritis patients compared with matched healthy control individuals. The carotid intima media thickness (IMT) is increased in rheumatoid arthritis (RA) patients compared with healthy control individuals matched for age, sex and cardiovascular risk factors. Representative ca...
PMC2246237_F6_17791.jpg
What is the principal component of this image?
Increased volume of popliteal lymph nodes in tumor necrosis factor-transgenic (TNF-Tg) mice. (a) A representative post-contrast magnetic resonance imaging slice from a TNF-Tg and wild-type (WT) mouse (5 months old). (b) Using a semi-automated segmentation procedure in Amira software, the synovial (yellow) and lymph nod...
PMC2246237_F6_17792.jpg
What is the focal point of this photograph?
Increased volume of popliteal lymph nodes in tumor necrosis factor-transgenic (TNF-Tg) mice. (a) A representative post-contrast magnetic resonance imaging slice from a TNF-Tg and wild-type (WT) mouse (5 months old). (b) Using a semi-automated segmentation procedure in Amira software, the synovial (yellow) and lymph nod...
PMC2246237_F6_17789.jpg
What is the focal point of this photograph?
Increased volume of popliteal lymph nodes in tumor necrosis factor-transgenic (TNF-Tg) mice. (a) A representative post-contrast magnetic resonance imaging slice from a TNF-Tg and wild-type (WT) mouse (5 months old). (b) Using a semi-automated segmentation procedure in Amira software, the synovial (yellow) and lymph nod...
PMC2246238_F1_17804.jpg
What object or scene is depicted here?
Ultrasonography (US) of distal interphalangeal (DIP) joints (a-c) and metatarsophalangeal (MTP) joints (d-f). Images on the left were acquired independently by ultrasonographer 1 (Charlotte Wiell) and middle images were acquired independently by ultrasonographer 2 (Marcin Szkudlarek) in the interobserver US substudy. (...
PMC2246238_F1_17802.jpg
What is the principal component of this image?
Ultrasonography (US) of distal interphalangeal (DIP) joints (a-c) and metatarsophalangeal (MTP) joints (d-f). Images on the left were acquired independently by ultrasonographer 1 (Charlotte Wiell) and middle images were acquired independently by ultrasonographer 2 (Marcin Szkudlarek) in the interobserver US substudy. (...
PMC2246238_F1_17801.jpg
What is the main focus of this visual representation?
Ultrasonography (US) of distal interphalangeal (DIP) joints (a-c) and metatarsophalangeal (MTP) joints (d-f). Images on the left were acquired independently by ultrasonographer 1 (Charlotte Wiell) and middle images were acquired independently by ultrasonographer 2 (Marcin Szkudlarek) in the interobserver US substudy. (...
PMC2246238_F1_17803.jpg
What is the principal component of this image?
Ultrasonography (US) of distal interphalangeal (DIP) joints (a-c) and metatarsophalangeal (MTP) joints (d-f). Images on the left were acquired independently by ultrasonographer 1 (Charlotte Wiell) and middle images were acquired independently by ultrasonographer 2 (Marcin Szkudlarek) in the interobserver US substudy. (...
PMC2246238_F1_17805.jpg
What stands out most in this visual?
Ultrasonography (US) of distal interphalangeal (DIP) joints (a-c) and metatarsophalangeal (MTP) joints (d-f). Images on the left were acquired independently by ultrasonographer 1 (Charlotte Wiell) and middle images were acquired independently by ultrasonographer 2 (Marcin Szkudlarek) in the interobserver US substudy. (...
PMC2246238_F2_17800.jpg
What is the main focus of this visual representation?
(a) Capsular/extracapsular changes (arrows) on power Doppler ultrasonography on the radial side of the 2nd proximal interphalangeal joint in a patient with psoriasis-associated arthritis. (b,c) The corresponding coronal T1-weighted magnetic resonance images before (b) and after (c) contrast administration showing capsu...
PMC2246238_F2_17798.jpg
Describe the main subject of this image.
(a) Capsular/extracapsular changes (arrows) on power Doppler ultrasonography on the radial side of the 2nd proximal interphalangeal joint in a patient with psoriasis-associated arthritis. (b,c) The corresponding coronal T1-weighted magnetic resonance images before (b) and after (c) contrast administration showing capsu...
PMC2246238_F3_17797.jpg
What can you see in this picture?
(a) Bone cortex defect (arrows) on ultrasonography in a 63-year-old healthy control person on the radial side of the 3rd proximal interphalangeal joint in a longitudinal view. (b) The corresponding transverse view. (c) The coronal T1-weighted magnetic resonance image without contrast administration reveals no erosion-l...
PMC2246238_F3_17796.jpg
What object or scene is depicted here?
(a) Bone cortex defect (arrows) on ultrasonography in a 63-year-old healthy control person on the radial side of the 3rd proximal interphalangeal joint in a longitudinal view. (b) The corresponding transverse view. (c) The coronal T1-weighted magnetic resonance image without contrast administration reveals no erosion-l...
PMC2246238_F3_17795.jpg
What is the focal point of this photograph?
(a) Bone cortex defect (arrows) on ultrasonography in a 63-year-old healthy control person on the radial side of the 3rd proximal interphalangeal joint in a longitudinal view. (b) The corresponding transverse view. (c) The coronal T1-weighted magnetic resonance image without contrast administration reveals no erosion-l...
PMC2246238_F4_17808.jpg
What is the dominant medical problem in this image?
Projection radiography (x-ray) (a) and T1-weighted coronal (b) and axial (c) magnetic resonance imaging (MRI) and ultrasonography (US) in longitudinal dorsal (d) and palmar (e) views of the 3rd distal interphalangeal joint of a patient with psoriasis-associated arthritis. An erosion was scored on x-ray (a) but not on e...
PMC2246238_F4_17811.jpg
What is shown in this image?
Projection radiography (x-ray) (a) and T1-weighted coronal (b) and axial (c) magnetic resonance imaging (MRI) and ultrasonography (US) in longitudinal dorsal (d) and palmar (e) views of the 3rd distal interphalangeal joint of a patient with psoriasis-associated arthritis. An erosion was scored on x-ray (a) but not on e...
PMC2248167_F1_17812.jpg
What does this image primarily show?
Anteroposterior radiographs obtained in a 67-year-old woman with painful right hip. View obtained 3 months after pain began reveals typical osteoarthritis
PMC2248169_F2_17827.jpg
What is being portrayed in this visual content?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F2_17828.jpg
What's the most prominent thing you notice in this picture?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F2_17823.jpg
What is the main focus of this visual representation?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F2_17824.jpg
What is the central feature of this picture?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F2_17826.jpg
What does this image primarily show?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F2_17829.jpg
What can you see in this picture?
A 68-year old lady fell on glazed frost and presented with acute back pain without neurological symptoms. The plain radiographs revealed osteoporotic fractures at L1 and L2 type A1.2 according to Magerl et al [18] without spinal stenosis in both CT and MRI (a). After kyphoplasty L1 and L2 and onset of a medical anti-os...
PMC2248169_F3_17821.jpg
What is the focal point of this photograph?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17816.jpg
What's the most prominent thing you notice in this picture?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17815.jpg
What is being portrayed in this visual content?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17819.jpg
What does this image primarily show?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17817.jpg
Can you identify the primary element in this image?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17822.jpg
What object or scene is depicted here?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F3_17814.jpg
Can you identify the primary element in this image?
A 77-year old man complained about severe thoracolumbar back pain. Plain radiographs revealed multiple osteoporotic vertebral compression fractures (a, b), of which fractures at Th9, Th11, and L1 were relatively fresh in the stir-sequence of the MRI (c). Because of severe pain resistant to non-surgical therapy for 2 mo...
PMC2248169_F4_17832.jpg
What is the main focus of this visual representation?
This 68-year old man with corticoid-induced secondary osteoporosis and multiple co-morbidity fell at home and presented with osteoporotic fractures at T12 and L1 (a, b). The MRI confirmed fresh fractures and revealed a spinal stenosis at T12/L1 (c). Since non-surgical therapy was not successful, neurological deficits w...
PMC2248169_F4_17836.jpg
What is shown in this image?
This 68-year old man with corticoid-induced secondary osteoporosis and multiple co-morbidity fell at home and presented with osteoporotic fractures at T12 and L1 (a, b). The MRI confirmed fresh fractures and revealed a spinal stenosis at T12/L1 (c). Since non-surgical therapy was not successful, neurological deficits w...
PMC2248169_F4_17837.jpg
What is the central feature of this picture?
This 68-year old man with corticoid-induced secondary osteoporosis and multiple co-morbidity fell at home and presented with osteoporotic fractures at T12 and L1 (a, b). The MRI confirmed fresh fractures and revealed a spinal stenosis at T12/L1 (c). Since non-surgical therapy was not successful, neurological deficits w...
PMC2248169_F4_17831.jpg
What's the most prominent thing you notice in this picture?
This 68-year old man with corticoid-induced secondary osteoporosis and multiple co-morbidity fell at home and presented with osteoporotic fractures at T12 and L1 (a, b). The MRI confirmed fresh fractures and revealed a spinal stenosis at T12/L1 (c). Since non-surgical therapy was not successful, neurological deficits w...
PMC2248172_F3_17841.jpg
What is the dominant medical problem in this image?
Immunofluorescence microscopy analysis of CXCR4 expression in permeabilized HIV-1 and mock infected RH9 cells. Four days after HIV-1 infection, cells were fixed, permeabilized with saponin and labeled with a mouse monoclonal antibody to CXCR4 (12G5) and a secondary, FITC-conjugated anti-mouse antibodies for observation...
PMC2248172_F3_17844.jpg
What does this image primarily show?
Immunofluorescence microscopy analysis of CXCR4 expression in permeabilized HIV-1 and mock infected RH9 cells. Four days after HIV-1 infection, cells were fixed, permeabilized with saponin and labeled with a mouse monoclonal antibody to CXCR4 (12G5) and a secondary, FITC-conjugated anti-mouse antibodies for observation...
PMC2248172_F3_17838.jpg
What is the dominant medical problem in this image?
Immunofluorescence microscopy analysis of CXCR4 expression in permeabilized HIV-1 and mock infected RH9 cells. Four days after HIV-1 infection, cells were fixed, permeabilized with saponin and labeled with a mouse monoclonal antibody to CXCR4 (12G5) and a secondary, FITC-conjugated anti-mouse antibodies for observation...
PMC2248172_F3_17840.jpg
What is the main focus of this visual representation?
Immunofluorescence microscopy analysis of CXCR4 expression in permeabilized HIV-1 and mock infected RH9 cells. Four days after HIV-1 infection, cells were fixed, permeabilized with saponin and labeled with a mouse monoclonal antibody to CXCR4 (12G5) and a secondary, FITC-conjugated anti-mouse antibodies for observation...
PMC2248172_F3_17842.jpg
What is shown in this image?
Immunofluorescence microscopy analysis of CXCR4 expression in permeabilized HIV-1 and mock infected RH9 cells. Four days after HIV-1 infection, cells were fixed, permeabilized with saponin and labeled with a mouse monoclonal antibody to CXCR4 (12G5) and a secondary, FITC-conjugated anti-mouse antibodies for observation...
PMC2248172_F4_17847.jpg
What is the central feature of this picture?
Co-localization CXCR4 and HIV-1 glycoprotein in HIV-1 infected H9 cells. Four days after HIV-1 infection, cells were fixed and permeabilized with saponin. Cells were then labeled with a human monoclonal antibody that interact with SU and then rhodamine-conjugated goat anti-human antibodies (Panel C: red fluorescence) a...
PMC2248172_F4_17848.jpg
What object or scene is depicted here?
Co-localization CXCR4 and HIV-1 glycoprotein in HIV-1 infected H9 cells. Four days after HIV-1 infection, cells were fixed and permeabilized with saponin. Cells were then labeled with a human monoclonal antibody that interact with SU and then rhodamine-conjugated goat anti-human antibodies (Panel C: red fluorescence) a...
PMC2248172_F4_17849.jpg
What can you see in this picture?
Co-localization CXCR4 and HIV-1 glycoprotein in HIV-1 infected H9 cells. Four days after HIV-1 infection, cells were fixed and permeabilized with saponin. Cells were then labeled with a human monoclonal antibody that interact with SU and then rhodamine-conjugated goat anti-human antibodies (Panel C: red fluorescence) a...
PMC2248172_F5_17856.jpg
What is the main focus of this visual representation?
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248172_F5_17851.jpg
Describe the main subject of this image.
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248172_F5_17854.jpg
What key item or scene is captured in this photo?
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248172_F5_17853.jpg
What is the principal component of this image?
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248172_F5_17850.jpg
What is being portrayed in this visual content?
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248172_F5_17852.jpg
What is the principal component of this image?
CXCR4 expression is reduced in Jurkat cells after induction of HIV-1 Env expression. After 4 days induction of HIV-1 Env proteins, non-induced and induced cells were fixed and labeled with a mouse MAb to CXCR4 (12G5) and a secondary FITC-conjugated anti-mouse antibodies for observation with a fluorescence microscopy. P...
PMC2248189_F3_17878.jpg
What can you see in this picture?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17870.jpg
What is the central feature of this picture?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17875.jpg
What's the most prominent thing you notice in this picture?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17871.jpg
What is the main focus of this visual representation?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17876.jpg
What is the core subject represented in this visual?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17867.jpg
What does this image primarily show?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17873.jpg
What is the central feature of this picture?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17869.jpg
Describe the main subject of this image.
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...
PMC2248189_F3_17872.jpg
What is the dominant medical problem in this image?
pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)...