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PMC2248189_F3_17868.jpg | What is the principal component of this image? | pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)... |
PMC2248189_F3_17864.jpg | What is the principal component of this image? | pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)... |
PMC2248189_F3_17865.jpg | What is the central feature of this picture? | pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)... |
PMC2248189_F3_17866.jpg | Describe the main subject of this image. | pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)... |
PMC2248189_F3_17877.jpg | What's the most prominent thing you notice in this picture? | pIN-KDEL is targeted to the endoplasmic reticulum. HEK293 cells transiently transfected with pIN-G (panels A-D), pIN-MDEL (panels E-H) and pIN-KDEL (panels I-L, P) were fixed at 48 h, permeabilized and treated with antibodies (See Materials and Methods) to the following organelle markers: Sec61β (Endoplasmic Reticulum)... |
PMC2248189_F4_17859.jpg | What is the principal component of this image? | Expression of pIN-KDEL reveals the dynamic morphology of the endoplasmic reticulum in live cells. COS-7 cells expressing pIN-KDEL were imaged 48 h post-transfection (Materials and Methods) and subjected to sequential recording of images at a rate of 1 frame/second (Supplemental movie 1). Image frames displayed at low m... |
PMC2248189_F4_17862.jpg | What is the central feature of this picture? | Expression of pIN-KDEL reveals the dynamic morphology of the endoplasmic reticulum in live cells. COS-7 cells expressing pIN-KDEL were imaged 48 h post-transfection (Materials and Methods) and subjected to sequential recording of images at a rate of 1 frame/second (Supplemental movie 1). Image frames displayed at low m... |
PMC2248189_F4_17858.jpg | What is the dominant medical problem in this image? | Expression of pIN-KDEL reveals the dynamic morphology of the endoplasmic reticulum in live cells. COS-7 cells expressing pIN-KDEL were imaged 48 h post-transfection (Materials and Methods) and subjected to sequential recording of images at a rate of 1 frame/second (Supplemental movie 1). Image frames displayed at low m... |
PMC2248189_F4_17861.jpg | What is the dominant medical problem in this image? | Expression of pIN-KDEL reveals the dynamic morphology of the endoplasmic reticulum in live cells. COS-7 cells expressing pIN-KDEL were imaged 48 h post-transfection (Materials and Methods) and subjected to sequential recording of images at a rate of 1 frame/second (Supplemental movie 1). Image frames displayed at low m... |
PMC2248189_F4_17863.jpg | What is the main focus of this visual representation? | Expression of pIN-KDEL reveals the dynamic morphology of the endoplasmic reticulum in live cells. COS-7 cells expressing pIN-KDEL were imaged 48 h post-transfection (Materials and Methods) and subjected to sequential recording of images at a rate of 1 frame/second (Supplemental movie 1). Image frames displayed at low m... |
PMC2248189_F7_17880.jpg | What is the principal component of this image? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17885.jpg | What stands out most in this visual? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17883.jpg | What is the core subject represented in this visual? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17887.jpg | What's the most prominent thing you notice in this picture? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17889.jpg | Can you identify the primary element in this image? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17882.jpg | What is the focal point of this photograph? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248189_F7_17881.jpg | What object or scene is depicted here? | Morphological dynamics in the endoplasmic reticulum of live astrocytes and neurones transduced with LV-pIN-KDEL. Rat astrocytes in dissociated culture (top panels) and cortical neurones in organotypic brain slice (Bottom panels; 2.5× magnified inset) were treated with LV-pIN-KDEL and imaged at 48–72 h post transduction... |
PMC2248208_F2_17895.jpg | Can you identify the primary element in this image? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17893.jpg | What is the dominant medical problem in this image? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17896.jpg | What is the dominant medical problem in this image? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17894.jpg | What is the central feature of this picture? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17892.jpg | What key item or scene is captured in this photo? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17897.jpg | What is shown in this image? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F2_17891.jpg | What can you see in this picture? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) detection of TGF-β2 in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 2A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cases (mR... |
PMC2248208_F3_17905.jpg | What is the focal point of this photograph? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17899.jpg | What key item or scene is captured in this photo? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17900.jpg | What key item or scene is captured in this photo? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17906.jpg | What is the main focus of this visual representation? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17901.jpg | What is the core subject represented in this visual? | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17904.jpg | Describe the main subject of this image. | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248208_F3_17902.jpg | Describe the main subject of this image. | Representative in situ RT-PCR (A-D) and immunohistochemical (E-H) determination of TGF-βRII in cervical tissue. Shown are histological cross-sections of the mouse cervical tract from Nt-E, Nt+E, E7-E and E7+E mice. Figure 3A and E: Nt-E mice; (B and F): Nt+E mice; (C and G): E7-E mice; (D and H): E7+E mice. In both cas... |
PMC2248243_fig1_17908.jpg | What is the focal point of this photograph? | Macular edema in diabetic
retinopathy. (a) Macular edema
in diabetic retinopathy. (b) Increased
vascular permeability is observed by fluorescin angiography. Note the leakage of the fluorescent dye
showing the blood retinal barrier breakdown.
Although the retinopathy is mild, this patient has a visual acuity of
20/200 d... |
PMC2248243_fig1_17907.jpg | What is the central feature of this picture? | Macular edema in diabetic
retinopathy. (a) Macular edema
in diabetic retinopathy. (b) Increased
vascular permeability is observed by fluorescin angiography. Note the leakage of the fluorescent dye
showing the blood retinal barrier breakdown.
Although the retinopathy is mild, this patient has a visual acuity of
20/200 d... |
PMC2248568_F1_17910.jpg | What is the principal component of this image? | A-B A transesophageal echocardiographic long axis and two chamber midesophageal view illustrating a flail anterior mitral valve leaflet with ruptured papillary muscle. |
PMC2248568_F2_17914.jpg | What's the most prominent thing you notice in this picture? | A-B A transesophageal echocardiographic long axis and two chamber midesophageal view with color Doppler demonstrating an eccentric posteriorly directed jet of severe mitral regurgitation. |
PMC2248573_F4_17915.jpg | What does this image primarily show? | This TOE shows the tip of the cannula lying at the level of the sinus of Valsalva with perfusion of the true lumen. |
PMC2248586_F1_17923.jpg | What key item or scene is captured in this photo? | Non-contrast head CT (Fig 1A) demonstrates frontal lobe hemorrhage (arrows). Source image from MRA of the brain (Fig 1B) demonstrates 8 mm aneurysm in the distal A1 segment of the right ACA (arrowheads). DSA (AP/oblique) from right ICA injections (Fig 1C) confirms aneurysm of the distal A1 ACA segment. 3-D TOF MRA abdo... |
PMC2248586_F1_17921.jpg | What can you see in this picture? | Non-contrast head CT (Fig 1A) demonstrates frontal lobe hemorrhage (arrows). Source image from MRA of the brain (Fig 1B) demonstrates 8 mm aneurysm in the distal A1 segment of the right ACA (arrowheads). DSA (AP/oblique) from right ICA injections (Fig 1C) confirms aneurysm of the distal A1 ACA segment. 3-D TOF MRA abdo... |
PMC2248586_F1_17925.jpg | What is shown in this image? | Non-contrast head CT (Fig 1A) demonstrates frontal lobe hemorrhage (arrows). Source image from MRA of the brain (Fig 1B) demonstrates 8 mm aneurysm in the distal A1 segment of the right ACA (arrowheads). DSA (AP/oblique) from right ICA injections (Fig 1C) confirms aneurysm of the distal A1 ACA segment. 3-D TOF MRA abdo... |
PMC2248586_F1_17924.jpg | What's the most prominent thing you notice in this picture? | Non-contrast head CT (Fig 1A) demonstrates frontal lobe hemorrhage (arrows). Source image from MRA of the brain (Fig 1B) demonstrates 8 mm aneurysm in the distal A1 segment of the right ACA (arrowheads). DSA (AP/oblique) from right ICA injections (Fig 1C) confirms aneurysm of the distal A1 ACA segment. 3-D TOF MRA abdo... |
PMC2248586_F1_17922.jpg | What key item or scene is captured in this photo? | Non-contrast head CT (Fig 1A) demonstrates frontal lobe hemorrhage (arrows). Source image from MRA of the brain (Fig 1B) demonstrates 8 mm aneurysm in the distal A1 segment of the right ACA (arrowheads). DSA (AP/oblique) from right ICA injections (Fig 1C) confirms aneurysm of the distal A1 ACA segment. 3-D TOF MRA abdo... |
PMC2248586_F2_17932.jpg | What's the most prominent thing you notice in this picture? | H&E stain (200×, Fig 2A; 400×, Fig 2B) from right internal iliac artery shows transmural vasculitis with intimal thickening (asterisks) and giant cells (arrowheads). Elastic stain reveals disruption of elastic lamina (Fig 2C). AP DSA, fusiform aneurysms supraclinoid left ICA (arrowheads; Fig 2D), right ICA (arrowheads;... |
PMC2248586_F2_17929.jpg | What does this image primarily show? | H&E stain (200×, Fig 2A; 400×, Fig 2B) from right internal iliac artery shows transmural vasculitis with intimal thickening (asterisks) and giant cells (arrowheads). Elastic stain reveals disruption of elastic lamina (Fig 2C). AP DSA, fusiform aneurysms supraclinoid left ICA (arrowheads; Fig 2D), right ICA (arrowheads;... |
PMC2248586_F2_17927.jpg | What does this image primarily show? | H&E stain (200×, Fig 2A; 400×, Fig 2B) from right internal iliac artery shows transmural vasculitis with intimal thickening (asterisks) and giant cells (arrowheads). Elastic stain reveals disruption of elastic lamina (Fig 2C). AP DSA, fusiform aneurysms supraclinoid left ICA (arrowheads; Fig 2D), right ICA (arrowheads;... |
PMC2248586_F2_17930.jpg | Describe the main subject of this image. | H&E stain (200×, Fig 2A; 400×, Fig 2B) from right internal iliac artery shows transmural vasculitis with intimal thickening (asterisks) and giant cells (arrowheads). Elastic stain reveals disruption of elastic lamina (Fig 2C). AP DSA, fusiform aneurysms supraclinoid left ICA (arrowheads; Fig 2D), right ICA (arrowheads;... |
PMC2248586_F2_17926.jpg | What is the main focus of this visual representation? | H&E stain (200×, Fig 2A; 400×, Fig 2B) from right internal iliac artery shows transmural vasculitis with intimal thickening (asterisks) and giant cells (arrowheads). Elastic stain reveals disruption of elastic lamina (Fig 2C). AP DSA, fusiform aneurysms supraclinoid left ICA (arrowheads; Fig 2D), right ICA (arrowheads;... |
PMC2248586_F3_17916.jpg | What stands out most in this visual? | Gross photograph, aortic and bilateral iliac artery aneurysms (Fig 3A). Left subclavian artery, focal intimal thickening (asterisks; H&E stain 40×, Fig 3B), transmural lymphohistiocytic infiltrate (asterisks; H&E 200×, Fig 3C), elastic lamina disruption (arrowheads; elastic stain 40×, Fig 3D). Gross photograph brain, s... |
PMC2248586_F3_17919.jpg | What is the principal component of this image? | Gross photograph, aortic and bilateral iliac artery aneurysms (Fig 3A). Left subclavian artery, focal intimal thickening (asterisks; H&E stain 40×, Fig 3B), transmural lymphohistiocytic infiltrate (asterisks; H&E 200×, Fig 3C), elastic lamina disruption (arrowheads; elastic stain 40×, Fig 3D). Gross photograph brain, s... |
PMC2248586_F3_17920.jpg | What stands out most in this visual? | Gross photograph, aortic and bilateral iliac artery aneurysms (Fig 3A). Left subclavian artery, focal intimal thickening (asterisks; H&E stain 40×, Fig 3B), transmural lymphohistiocytic infiltrate (asterisks; H&E 200×, Fig 3C), elastic lamina disruption (arrowheads; elastic stain 40×, Fig 3D). Gross photograph brain, s... |
PMC2248586_F3_17917.jpg | What object or scene is depicted here? | Gross photograph, aortic and bilateral iliac artery aneurysms (Fig 3A). Left subclavian artery, focal intimal thickening (asterisks; H&E stain 40×, Fig 3B), transmural lymphohistiocytic infiltrate (asterisks; H&E 200×, Fig 3C), elastic lamina disruption (arrowheads; elastic stain 40×, Fig 3D). Gross photograph brain, s... |
PMC2248592_F3_17933.jpg | What is shown in this image? | A) Intraoperative view showing the exposed cystic projection of the hydatid cyst with a purse string all around. B) Daughter cysts being sucked through the laparoscopic trocar sheath. (Inset: suction bottle containing cyst contents.) |
PMC2248620_pone-0001673-g003_17939.jpg | What can you see in this picture? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17938.jpg | Can you identify the primary element in this image? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17936.jpg | What is the central feature of this picture? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17940.jpg | What does this image primarily show? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17941.jpg | What is shown in this image? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17935.jpg | What does this image primarily show? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248620_pone-0001673-g003_17937.jpg | What object or scene is depicted here? | Immunohistological detection of SP expression in respiratory tissue.Groups of 143-YAChPPT-ALacZ mice (Panels A-E) and BALB/c mice (Panels F-H) were infected with MHV-68 or mock-infected and euthanized at various time-points post-infection. Micrographs show airway and lung tissue sections stained for the presence of SP ... |
PMC2248623_pone-0001709-g002_17945.jpg | What does this image primarily show? | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17950.jpg | Describe the main subject of this image. | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17949.jpg | What is the central feature of this picture? | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17942.jpg | Describe the main subject of this image. | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17952.jpg | What does this image primarily show? | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17948.jpg | What object or scene is depicted here? | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2248623_pone-0001709-g002_17951.jpg | What is the dominant medical problem in this image? | Growth and somatic development of Snord116del mice.A. Daily weight curves for males (left) and weekly weight curves for males (middle) and females (right). The female weight curve in the first month (not shown) overlaps with the male curve. Error bars, standard deviations. Significant weight differences between Snord11... |
PMC2249566_F2_17954.jpg | What stands out most in this visual? | Scanning electron micrographs showing how nuclear morphometry was performed. A. Measurements of elliptical angles in the fetal nucleus (FN) were made on micrographs of split lens nuclei, allowing for exposure of the radial cell columns. A distance of 1 mm was measured from the lens center (white line) and the fetal fib... |
PMC2249566_F2_17955.jpg | What is the main focus of this visual representation? | Scanning electron micrographs showing how nuclear morphometry was performed. A. Measurements of elliptical angles in the fetal nucleus (FN) were made on micrographs of split lens nuclei, allowing for exposure of the radial cell columns. A distance of 1 mm was measured from the lens center (white line) and the fetal fib... |
PMC2249566_F2_17957.jpg | What stands out most in this visual? | Scanning electron micrographs showing how nuclear morphometry was performed. A. Measurements of elliptical angles in the fetal nucleus (FN) were made on micrographs of split lens nuclei, allowing for exposure of the radial cell columns. A distance of 1 mm was measured from the lens center (white line) and the fetal fib... |
PMC2249566_F2_17956.jpg | What can you see in this picture? | Scanning electron micrographs showing how nuclear morphometry was performed. A. Measurements of elliptical angles in the fetal nucleus (FN) were made on micrographs of split lens nuclei, allowing for exposure of the radial cell columns. A distance of 1 mm was measured from the lens center (white line) and the fetal fib... |
PMC2249582_F1_17960.jpg | What is the principal component of this image? | In the upper left panel a pericardial view (frontal) showing the edge of both atria which are preserved for conventional surgical technique (Shumway technique): possibility of interatrial ridge are dependent of the redundancy of donor as well as recipient residual tissue (arrows). In the upper right panel pericardial v... |
PMC2249582_F1_17961.jpg | Can you identify the primary element in this image? | In the upper left panel a pericardial view (frontal) showing the edge of both atria which are preserved for conventional surgical technique (Shumway technique): possibility of interatrial ridge are dependent of the redundancy of donor as well as recipient residual tissue (arrows). In the upper right panel pericardial v... |
PMC2249582_F5_17959.jpg | What is the dominant medical problem in this image? | Use of 2-D echocardiography for monitoring the performance of endomyocardial biopsy in a HT recipient. The arrow indicates the site of the biopsy. Left panel: at the apex of right ventricle, right panel: al the level of the right side of the interventricular septum. |
PMC2249582_F5_17958.jpg | Can you identify the primary element in this image? | Use of 2-D echocardiography for monitoring the performance of endomyocardial biopsy in a HT recipient. The arrow indicates the site of the biopsy. Left panel: at the apex of right ventricle, right panel: al the level of the right side of the interventricular septum. |
PMC2249586_F2_17963.jpg | What stands out most in this visual? | (A) Posterior view of a pancreaticoduodenectomy specimen with periampullary adenocarcinoma infiltrating the retroperitoneal resection margin. The specimen includes the pyloric part of the stomach (st), the duodenum (du), adipose tissue which is part of the greater omentum, and the head and uncinate process of pancreas.... |
PMC2249586_F2_17964.jpg | What object or scene is depicted here? | (A) Posterior view of a pancreaticoduodenectomy specimen with periampullary adenocarcinoma infiltrating the retroperitoneal resection margin. The specimen includes the pyloric part of the stomach (st), the duodenum (du), adipose tissue which is part of the greater omentum, and the head and uncinate process of pancreas.... |
PMC2249586_F2_17965.jpg | What is the central feature of this picture? | (A) Posterior view of a pancreaticoduodenectomy specimen with periampullary adenocarcinoma infiltrating the retroperitoneal resection margin. The specimen includes the pyloric part of the stomach (st), the duodenum (du), adipose tissue which is part of the greater omentum, and the head and uncinate process of pancreas.... |
PMC2249590_F2_17985.jpg | What is the principal component of this image? | Axial contrast-enhanced computed tomography (CT) scan 3 cm caudal from the mamilla displaying the approximate depth of the 50% isodose from the CT-determined 9 MeV electron beam. In this 65-years-old non-cancer patient with previous heart disease, parts of the left ventricle would be exposed to unexpected doses of ioni... |
PMC2249590_F3_17987.jpg | Can you identify the primary element in this image? | Axial contrast-enhanced computed tomography scan 3 cm caudal from the mamilla displaying on the lower image the approximate depth of the 50% isodose from a standard 9 MeV electron beam (6 MeV would have been appropriate). 3-D planning illustrates that the actual dose to the heart is even higher. The left ventricle (con... |
PMC2249590_F3_17988.jpg | What is the dominant medical problem in this image? | Axial contrast-enhanced computed tomography scan 3 cm caudal from the mamilla displaying on the lower image the approximate depth of the 50% isodose from a standard 9 MeV electron beam (6 MeV would have been appropriate). 3-D planning illustrates that the actual dose to the heart is even higher. The left ventricle (con... |
PMC2249593_F2_17970.jpg | What stands out most in this visual? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17971.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17982.jpg | What is the principal component of this image? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17980.jpg | What is the central feature of this picture? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17968.jpg | What object or scene is depicted here? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17984.jpg | What is the principal component of this image? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17976.jpg | Describe the main subject of this image. | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17975.jpg | What is the main focus of this visual representation? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17981.jpg | What is the core subject represented in this visual? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17969.jpg | What is the dominant medical problem in this image? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17977.jpg | What is the main focus of this visual representation? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249593_F2_17972.jpg | What does this image primarily show? | Immunohistochemical examination of Bcl-2 family members and death receptors. Immunohistochemistry was performed to measure the expression of Bak, Bax, Bcl-2, Bcl-XL, TRAIL-R1/DR4 and TRAIL-R2/DR5 in tumor tissues derived from control and/or treated mice on week 6. |
PMC2249600_F1_17989.jpg | What is being portrayed in this visual content? | Plain abdominal radiography. |
PMC2249600_F1_17990.jpg | What is the main focus of this visual representation? | Plain abdominal radiography. |
PMC2249601_F1_17991.jpg | What is the focal point of this photograph? | Chest Radiograph. |
PMC2249601_F1_17992.jpg | Can you identify the primary element in this image? | Chest Radiograph. |
PMC2249602_F1_17994.jpg | What is shown in this image? | MRI findings one month before initiation of thalidomide, showing marked enhancement of infundibulum (6 mm) and bilateral optic nerves (6 mm). |
PMC2249602_F2_17995.jpg | What is being portrayed in this visual content? | MRI Brain with contrast demonstrating improvement 2 months after initiation of thalidomide. |
PMC2249602_F3_17996.jpg | What can you see in this picture? | MRI brain with contrast showing near resolution of enhancement, stable on serial MRIs for 2 years. |
PMC2249706_pone-0001734-g005_17997.jpg | Describe the main subject of this image. | Treatment attenuated target organ injury.(A) Example of a dense cataract observed only in untreated diabetic pigs. (B) Retinal fluorescein angiography showed normal capillary permeability. (C) TEM of retina showed thickened basement membrane of a choroidal capillary, duplicated basement membrane (red arrow) and an extr... |
PMC2249706_pone-0001734-g005_18000.jpg | What is the core subject represented in this visual? | Treatment attenuated target organ injury.(A) Example of a dense cataract observed only in untreated diabetic pigs. (B) Retinal fluorescein angiography showed normal capillary permeability. (C) TEM of retina showed thickened basement membrane of a choroidal capillary, duplicated basement membrane (red arrow) and an extr... |
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