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PMC2360416_fig5_21234.jpg | What object or scene is depicted here? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21243.jpg | What is shown in this image? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21238.jpg | What is the dominant medical problem in this image? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21239.jpg | What's the most prominent thing you notice in this picture? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21233.jpg | What is shown in this image? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21237.jpg | What is the central feature of this picture? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21232.jpg | Can you identify the primary element in this image? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360416_fig5_21236.jpg | What is the core subject represented in this visual? | Cell proliferation and morphology post-removal of benzyl-α-GalNAc. (A) Capan-1 and (B) HPAF-II cells (1 × 104 cells per ml) were exposed to 0.4 and 0.8 mg ml−1 of benzyl-α-GalNAc, respectively. Following 48 h exposure to benzyl-α-GalNAc the cells were washed with 1 × PBS and allowed to grow for next 24, 48 and 72 h in ... |
PMC2360420_fig1_21249.jpg | What stands out most in this visual? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360420_fig1_21248.jpg | What stands out most in this visual? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360420_fig1_21244.jpg | What is shown in this image? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360420_fig1_21245.jpg | What is the core subject represented in this visual? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360420_fig1_21247.jpg | What object or scene is depicted here? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360420_fig1_21246.jpg | What is the focal point of this photograph? | Left: examples of tissue with immunostaining for the more significant proteins in patients with tumours belong to poor prognostic group (cluster 2 group: A, B and C) and better prognostic group (cluster 1 group: D, E and F; magnification × 400). (A) Immunohistochemical staining of matrix metalloproteinase (MMP)-11 in i... |
PMC2360491_fig3_21251.jpg | What is the focal point of this photograph? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded normal breast tissue. (A) Immunoperoxidase staining shows the antigen (pro)renin was present in myoepithelial cells (red arrow). Staining was absent from epithelial cells (black arrow) and connective tissues (yellow arrow). In fibroadenoma (C), i... |
PMC2360491_fig4_21264.jpg | What is the main focus of this visual representation? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360491_fig4_21265.jpg | What is the focal point of this photograph? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360491_fig4_21261.jpg | What is the dominant medical problem in this image? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360491_fig4_21260.jpg | Can you identify the primary element in this image? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360491_fig4_21263.jpg | Describe the main subject of this image. | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360491_fig4_21262.jpg | What object or scene is depicted here? | (Pro)renin was localised in sections of formalin-fixed, paraffin-embedded ductal carcinoma in situ. (A) Immunoperoxidase staining shows the antigen was present in myoepithelial cells (red arrow) and fibroblasts (yellow arrow). Staining was absent from epithelial (cancer) cells (black arrow). In infiltrating ductal carc... |
PMC2360493_fig1_21255.jpg | What is the principal component of this image? | Representative images of ING2 immunohistochemical staining in human melanocytic lesions. Strong ING2 expression in adjacent normal epidermis (A), normal nevi (B), dysplastic nevi (C), and weak ING2 staining in primary melanoma (D) and metastatic melanoma (E). Arrows indicate strong staining in melanocyte. Magnification... |
PMC2360493_fig1_21254.jpg | What is the main focus of this visual representation? | Representative images of ING2 immunohistochemical staining in human melanocytic lesions. Strong ING2 expression in adjacent normal epidermis (A), normal nevi (B), dysplastic nevi (C), and weak ING2 staining in primary melanoma (D) and metastatic melanoma (E). Arrows indicate strong staining in melanocyte. Magnification... |
PMC2360493_fig1_21256.jpg | What is the central feature of this picture? | Representative images of ING2 immunohistochemical staining in human melanocytic lesions. Strong ING2 expression in adjacent normal epidermis (A), normal nevi (B), dysplastic nevi (C), and weak ING2 staining in primary melanoma (D) and metastatic melanoma (E). Arrows indicate strong staining in melanocyte. Magnification... |
PMC2360493_fig1_21257.jpg | What can you see in this picture? | Representative images of ING2 immunohistochemical staining in human melanocytic lesions. Strong ING2 expression in adjacent normal epidermis (A), normal nevi (B), dysplastic nevi (C), and weak ING2 staining in primary melanoma (D) and metastatic melanoma (E). Arrows indicate strong staining in melanocyte. Magnification... |
PMC2360501_fig4_21266.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical sections from (A) p53+/+ (× 400) and (B) p53−/− mouse small intestinal crypts (× 500) stained for p21WAF1 48 h following 200 mg kg−1 5-FU and 250 mg kg−1 PDTC. |
PMC2360501_fig4_21267.jpg | What is the dominant medical problem in this image? | Immunohistochemical sections from (A) p53+/+ (× 400) and (B) p53−/− mouse small intestinal crypts (× 500) stained for p21WAF1 48 h following 200 mg kg−1 5-FU and 250 mg kg−1 PDTC. |
PMC2360534_fig4_21269.jpg | What is being portrayed in this visual content? | Comparative immunohistochemistry for PPARδ and Ki-67 expression. A concordant distribution of Ki-67-expressing colon cancer cells and those with cytoplasmic accumulation of PPARδ. Magnifications: × 20. |
PMC2360534_fig4_21268.jpg | What can you see in this picture? | Comparative immunohistochemistry for PPARδ and Ki-67 expression. A concordant distribution of Ki-67-expressing colon cancer cells and those with cytoplasmic accumulation of PPARδ. Magnifications: × 20. |
PMC2360534_fig5_21274.jpg | What can you see in this picture? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21275.jpg | What is the main focus of this visual representation? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21270.jpg | What key item or scene is captured in this photo? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21276.jpg | Can you identify the primary element in this image? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21271.jpg | What does this image primarily show? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21278.jpg | Describe the main subject of this image. | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21272.jpg | Describe the main subject of this image. | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360534_fig5_21273.jpg | What does this image primarily show? | Peroxisome proliferator-activated receptor δ expression and morphology of CRC cells. (A) PPARδ-positive cancer cells presented morphological features associated with high malignant potential including a large nucleus, globular nuclear shape, appearance of a distinct nucleolus, and loss of cellular polarity. (B) PPARδ-n... |
PMC2360542_fig6_21282.jpg | What is the core subject represented in this visual? | Immunocytochemistry for the detection of cleaved caspase 3-positive cells. (A and C) Control untreated cells (SK-N-AS and SH-SY5Y, respectively). (B and D) RGZ-treated cells (SK-N-AS and SH-SY5Y, respectively). Magnification × 40. |
PMC2360542_fig6_21280.jpg | What is the main focus of this visual representation? | Immunocytochemistry for the detection of cleaved caspase 3-positive cells. (A and C) Control untreated cells (SK-N-AS and SH-SY5Y, respectively). (B and D) RGZ-treated cells (SK-N-AS and SH-SY5Y, respectively). Magnification × 40. |
PMC2360542_fig6_21281.jpg | What is being portrayed in this visual content? | Immunocytochemistry for the detection of cleaved caspase 3-positive cells. (A and C) Control untreated cells (SK-N-AS and SH-SY5Y, respectively). (B and D) RGZ-treated cells (SK-N-AS and SH-SY5Y, respectively). Magnification × 40. |
PMC2360542_fig6_21283.jpg | What is the core subject represented in this visual? | Immunocytochemistry for the detection of cleaved caspase 3-positive cells. (A and C) Control untreated cells (SK-N-AS and SH-SY5Y, respectively). (B and D) RGZ-treated cells (SK-N-AS and SH-SY5Y, respectively). Magnification × 40. |
PMC2360577_fig1_21284.jpg | What key item or scene is captured in this photo? | (A) Patient No. 8 chest CT shows mediastinal lymph nodes at diagnosis (arrrowheads). (B) Mediastinal lymph node swelling disappeared after immunotherapy (CR). |
PMC2360577_fig1_21285.jpg | What stands out most in this visual? | (A) Patient No. 8 chest CT shows mediastinal lymph nodes at diagnosis (arrrowheads). (B) Mediastinal lymph node swelling disappeared after immunotherapy (CR). |
PMC2360585_fig2_21288.jpg | What is the principal component of this image? | Primary cultures of diseased PMP tissue and paired abdominal skin. Phase-contrast images of the cell cultures grown in the enriched ALC-4 medium. (A) Fibroblast cells grown in skin. (B) PMP culture at early passage 2 showing the two cell types – ‘fibroblastic’ cell type and grape-like clusters. One of the PMCA (PMP12) ... |
PMC2360585_fig2_21287.jpg | What is the dominant medical problem in this image? | Primary cultures of diseased PMP tissue and paired abdominal skin. Phase-contrast images of the cell cultures grown in the enriched ALC-4 medium. (A) Fibroblast cells grown in skin. (B) PMP culture at early passage 2 showing the two cell types – ‘fibroblastic’ cell type and grape-like clusters. One of the PMCA (PMP12) ... |
PMC2360585_fig2_21289.jpg | Describe the main subject of this image. | Primary cultures of diseased PMP tissue and paired abdominal skin. Phase-contrast images of the cell cultures grown in the enriched ALC-4 medium. (A) Fibroblast cells grown in skin. (B) PMP culture at early passage 2 showing the two cell types – ‘fibroblastic’ cell type and grape-like clusters. One of the PMCA (PMP12) ... |
PMC2360585_fig2_21286.jpg | Can you identify the primary element in this image? | Primary cultures of diseased PMP tissue and paired abdominal skin. Phase-contrast images of the cell cultures grown in the enriched ALC-4 medium. (A) Fibroblast cells grown in skin. (B) PMP culture at early passage 2 showing the two cell types – ‘fibroblastic’ cell type and grape-like clusters. One of the PMCA (PMP12) ... |
PMC2360617_fig2_21290.jpg | What object or scene is depicted here? | Effect of THC administration on tumour growth. Tumour growth plots and gadolinium-enhanced T1-weighted magnetic resonance scans after the second surgery in three patients. Arrows indicate the THC administration cycles. (A) Patient 3, scans before and after surgery of tumour relapse as well as after the second, fourth a... |
PMC2360617_fig2_21297.jpg | What is the focal point of this photograph? | Effect of THC administration on tumour growth. Tumour growth plots and gadolinium-enhanced T1-weighted magnetic resonance scans after the second surgery in three patients. Arrows indicate the THC administration cycles. (A) Patient 3, scans before and after surgery of tumour relapse as well as after the second, fourth a... |
PMC2360617_fig2_21291.jpg | What stands out most in this visual? | Effect of THC administration on tumour growth. Tumour growth plots and gadolinium-enhanced T1-weighted magnetic resonance scans after the second surgery in three patients. Arrows indicate the THC administration cycles. (A) Patient 3, scans before and after surgery of tumour relapse as well as after the second, fourth a... |
PMC2360617_fig2_21295.jpg | What's the most prominent thing you notice in this picture? | Effect of THC administration on tumour growth. Tumour growth plots and gadolinium-enhanced T1-weighted magnetic resonance scans after the second surgery in three patients. Arrows indicate the THC administration cycles. (A) Patient 3, scans before and after surgery of tumour relapse as well as after the second, fourth a... |
PMC2360617_fig2_21294.jpg | Describe the main subject of this image. | Effect of THC administration on tumour growth. Tumour growth plots and gadolinium-enhanced T1-weighted magnetic resonance scans after the second surgery in three patients. Arrows indicate the THC administration cycles. (A) Patient 3, scans before and after surgery of tumour relapse as well as after the second, fourth a... |
PMC2360619_fig1_21298.jpg | What is being portrayed in this visual content? | Sebaceous carcinoma: haematoxylin and eosin (× 100): multilobulated expansile intradermal tumour showing large polygonal cells with differentiation into sebaceous cells, altered nuclear/cytoplasmic ratio, evidence of apoptosis and high mitotic count. Insert: MSH2 immunohistochemical stain (× 400): Absence of nuclear st... |
PMC2360621_fig1_21299.jpg | What can you see in this picture? | Comparative morphologic evaluation (FNA vs LNAB) of micro follicular/solid thyroid nodule (panels A and B) and follicular nodule with mixed architecture (panels C and D). Cell blocks/microhistology clearly provide better morphologic details of the lesions (panels B and D). |
PMC2360621_fig1_21302.jpg | What stands out most in this visual? | Comparative morphologic evaluation (FNA vs LNAB) of micro follicular/solid thyroid nodule (panels A and B) and follicular nodule with mixed architecture (panels C and D). Cell blocks/microhistology clearly provide better morphologic details of the lesions (panels B and D). |
PMC2360621_fig1_21300.jpg | What's the most prominent thing you notice in this picture? | Comparative morphologic evaluation (FNA vs LNAB) of micro follicular/solid thyroid nodule (panels A and B) and follicular nodule with mixed architecture (panels C and D). Cell blocks/microhistology clearly provide better morphologic details of the lesions (panels B and D). |
PMC2360632_fig4_21303.jpg | What is the dominant medical problem in this image? | Invasive breast cancer specimens from the tissue microarray with (A) negative, (B) moderate, and (C) strong positive staining reaction for PRL-3. (D) Strong PLR-3 staining of tumour vessel. (E) PRL-3 negative and (F) positive lymph node metastases. Magnification 10-fold. |
PMC2360632_fig4_21307.jpg | What does this image primarily show? | Invasive breast cancer specimens from the tissue microarray with (A) negative, (B) moderate, and (C) strong positive staining reaction for PRL-3. (D) Strong PLR-3 staining of tumour vessel. (E) PRL-3 negative and (F) positive lymph node metastases. Magnification 10-fold. |
PMC2360632_fig4_21304.jpg | What is the focal point of this photograph? | Invasive breast cancer specimens from the tissue microarray with (A) negative, (B) moderate, and (C) strong positive staining reaction for PRL-3. (D) Strong PLR-3 staining of tumour vessel. (E) PRL-3 negative and (F) positive lymph node metastases. Magnification 10-fold. |
PMC2360632_fig4_21306.jpg | What is the principal component of this image? | Invasive breast cancer specimens from the tissue microarray with (A) negative, (B) moderate, and (C) strong positive staining reaction for PRL-3. (D) Strong PLR-3 staining of tumour vessel. (E) PRL-3 negative and (F) positive lymph node metastases. Magnification 10-fold. |
PMC2360640_fig3_21311.jpg | What is being portrayed in this visual content? | Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at ×... |
PMC2360640_fig3_21309.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at ×... |
PMC2360640_fig3_21314.jpg | Describe the main subject of this image. | Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at ×... |
PMC2360640_fig3_21310.jpg | Can you identify the primary element in this image? | Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at ×... |
PMC2360640_fig3_21313.jpg | Can you identify the primary element in this image? | Immunohistochemical analysis of CD70 in RCCs. CD70 expression throughout the carcinoma tissues of frozen sections of clear cell RCC (ccRCC) is shown (panels i–iii) relative to an isotype matched control antibody (panel iv). CD70 expression was not seen in normal kidney tissues (panel v). Panels i–v all show images at ×... |
PMC2360640_fig4_21315.jpg | What key item or scene is captured in this photo? | Immunohistochemical analysis demonstrating that CD70 expression is retained in metastatic tissues derived from primary ccRCC donors. CD70 expression in a primary ccRCC tissue (panel i) is shown alongside expression in a section of adrenal gland metastasis from the same donor (panel ii). Panels iii and iv show CD70 expr... |
PMC2360640_fig4_21317.jpg | What is the main focus of this visual representation? | Immunohistochemical analysis demonstrating that CD70 expression is retained in metastatic tissues derived from primary ccRCC donors. CD70 expression in a primary ccRCC tissue (panel i) is shown alongside expression in a section of adrenal gland metastasis from the same donor (panel ii). Panels iii and iv show CD70 expr... |
PMC2360640_fig4_21316.jpg | What is shown in this image? | Immunohistochemical analysis demonstrating that CD70 expression is retained in metastatic tissues derived from primary ccRCC donors. CD70 expression in a primary ccRCC tissue (panel i) is shown alongside expression in a section of adrenal gland metastasis from the same donor (panel ii). Panels iii and iv show CD70 expr... |
PMC2360665_fig2_21321.jpg | What does this image primarily show? | Immunohistochemistry with CEACAM6 antibody in intrahepatic cholangiocarcinoma. The majority of stain was observed in cancer cells. (A) original magnification × 40, haematoxylin and eosin stain, (B) original magnification × 40, CEACAM6 stain, (C) original magnification × 100, haematoxylin and eosin stain, (D) original m... |
PMC2360665_fig2_21320.jpg | What is the core subject represented in this visual? | Immunohistochemistry with CEACAM6 antibody in intrahepatic cholangiocarcinoma. The majority of stain was observed in cancer cells. (A) original magnification × 40, haematoxylin and eosin stain, (B) original magnification × 40, CEACAM6 stain, (C) original magnification × 100, haematoxylin and eosin stain, (D) original m... |
PMC2360665_fig2_21322.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemistry with CEACAM6 antibody in intrahepatic cholangiocarcinoma. The majority of stain was observed in cancer cells. (A) original magnification × 40, haematoxylin and eosin stain, (B) original magnification × 40, CEACAM6 stain, (C) original magnification × 100, haematoxylin and eosin stain, (D) original m... |
PMC2360665_fig2_21319.jpg | What key item or scene is captured in this photo? | Immunohistochemistry with CEACAM6 antibody in intrahepatic cholangiocarcinoma. The majority of stain was observed in cancer cells. (A) original magnification × 40, haematoxylin and eosin stain, (B) original magnification × 40, CEACAM6 stain, (C) original magnification × 100, haematoxylin and eosin stain, (D) original m... |
PMC2360674_fig1_21327.jpg | What is the central feature of this picture? | Methotrexate pretreatment stimulates the accumulation of PpIX in LNCaP cells. LNCaP cells, seeded in 35 mm dishes 1 day previously, were incubated in culture medium containing MTX (1 mg l−1; +MTX), or in medium without additives (−MTX). After 72 h, ALA was added to some of the dishes (0.3 mM, +ALA; middle and right pan... |
PMC2360674_fig1_21323.jpg | What is the principal component of this image? | Methotrexate pretreatment stimulates the accumulation of PpIX in LNCaP cells. LNCaP cells, seeded in 35 mm dishes 1 day previously, were incubated in culture medium containing MTX (1 mg l−1; +MTX), or in medium without additives (−MTX). After 72 h, ALA was added to some of the dishes (0.3 mM, +ALA; middle and right pan... |
PMC2360674_fig1_21325.jpg | Describe the main subject of this image. | Methotrexate pretreatment stimulates the accumulation of PpIX in LNCaP cells. LNCaP cells, seeded in 35 mm dishes 1 day previously, were incubated in culture medium containing MTX (1 mg l−1; +MTX), or in medium without additives (−MTX). After 72 h, ALA was added to some of the dishes (0.3 mM, +ALA; middle and right pan... |
PMC2360675_fig1_21330.jpg | What does this image primarily show? | Prostate cancer tissue staining for AMACR. High levels of the prostate cancer biomarker AMACR (green) stained mainly in clinically localised prostate cancer glands compared with internal adjacent benign glands. A higher magnification image is included on the right, and membrane E-cadherin expression is shown in red. |
PMC2360675_fig1_21329.jpg | Can you identify the primary element in this image? | Prostate cancer tissue staining for AMACR. High levels of the prostate cancer biomarker AMACR (green) stained mainly in clinically localised prostate cancer glands compared with internal adjacent benign glands. A higher magnification image is included on the right, and membrane E-cadherin expression is shown in red. |
PMC2360679_fig1_21339.jpg | What does this image primarily show? | (A) Validation of ERβ2/cx antibody (mouse monoclonal, clone 57/3, Serotec, UK): (a) Serotec clone 57/3 antibody staining of section from cell pellet of doxycycline treated tet-on-MDA231 cells stably overexpressing ERβ2/cx, magnification × 500; (b) same as (a), magnification × 1250; (c) Serotec clone 57/3 antibody stain... |
PMC2360679_fig2_21337.jpg | What key item or scene is captured in this photo? | Expression of ERβ and Ki67 in ERα-negative tissue microarray cores. (A–C) ERα-negative tumour cores stained with the specific ERβ1 antibody (GC17/385P) showing negative, medium and high expression (a–c; H-scores of 0, 150 and 225, respectively); (D–F) ERα-negative tumour cores stained with total ERβ antibody (14C8) sho... |
PMC2360679_fig2_21335.jpg | What key item or scene is captured in this photo? | Expression of ERβ and Ki67 in ERα-negative tissue microarray cores. (A–C) ERα-negative tumour cores stained with the specific ERβ1 antibody (GC17/385P) showing negative, medium and high expression (a–c; H-scores of 0, 150 and 225, respectively); (D–F) ERα-negative tumour cores stained with total ERβ antibody (14C8) sho... |
PMC2360679_fig2_21332.jpg | Can you identify the primary element in this image? | Expression of ERβ and Ki67 in ERα-negative tissue microarray cores. (A–C) ERα-negative tumour cores stained with the specific ERβ1 antibody (GC17/385P) showing negative, medium and high expression (a–c; H-scores of 0, 150 and 225, respectively); (D–F) ERα-negative tumour cores stained with total ERβ antibody (14C8) sho... |
PMC2360679_fig2_21333.jpg | What's the most prominent thing you notice in this picture? | Expression of ERβ and Ki67 in ERα-negative tissue microarray cores. (A–C) ERα-negative tumour cores stained with the specific ERβ1 antibody (GC17/385P) showing negative, medium and high expression (a–c; H-scores of 0, 150 and 225, respectively); (D–F) ERα-negative tumour cores stained with total ERβ antibody (14C8) sho... |
PMC2360679_fig2_21338.jpg | What is being portrayed in this visual content? | Expression of ERβ and Ki67 in ERα-negative tissue microarray cores. (A–C) ERα-negative tumour cores stained with the specific ERβ1 antibody (GC17/385P) showing negative, medium and high expression (a–c; H-scores of 0, 150 and 225, respectively); (D–F) ERα-negative tumour cores stained with total ERβ antibody (14C8) sho... |
PMC2360696_fig3_21345.jpg | Can you identify the primary element in this image? | Ultrastructure of adipocytes obtained from epididymal adipose tissue. Representative electron micrograph shows adipocytes from a control mouse containing a large lipid droplet and a thin rim of cytoplasm (A). Adipocytes from a tumour-bearing mouse show marked reductions in size with dilated interadipocyte space (B). Ad... |
PMC2360696_fig3_21341.jpg | What's the most prominent thing you notice in this picture? | Ultrastructure of adipocytes obtained from epididymal adipose tissue. Representative electron micrograph shows adipocytes from a control mouse containing a large lipid droplet and a thin rim of cytoplasm (A). Adipocytes from a tumour-bearing mouse show marked reductions in size with dilated interadipocyte space (B). Ad... |
PMC2360696_fig3_21342.jpg | What's the most prominent thing you notice in this picture? | Ultrastructure of adipocytes obtained from epididymal adipose tissue. Representative electron micrograph shows adipocytes from a control mouse containing a large lipid droplet and a thin rim of cytoplasm (A). Adipocytes from a tumour-bearing mouse show marked reductions in size with dilated interadipocyte space (B). Ad... |
PMC2360696_fig3_21346.jpg | What key item or scene is captured in this photo? | Ultrastructure of adipocytes obtained from epididymal adipose tissue. Representative electron micrograph shows adipocytes from a control mouse containing a large lipid droplet and a thin rim of cytoplasm (A). Adipocytes from a tumour-bearing mouse show marked reductions in size with dilated interadipocyte space (B). Ad... |
PMC2360715_fig2_21348.jpg | What is the principal component of this image? | Chest X-ray (A) and CT (B) on day 30 in the patient who developed ILD. Interstitial lung disease was hardly recognisable on chest X-ray, whereas chest CT revealed a patchy, ground-glass opacity with centrilobular distribution throughout the whole lung. |
PMC2360715_fig2_21347.jpg | What is being portrayed in this visual content? | Chest X-ray (A) and CT (B) on day 30 in the patient who developed ILD. Interstitial lung disease was hardly recognisable on chest X-ray, whereas chest CT revealed a patchy, ground-glass opacity with centrilobular distribution throughout the whole lung. |
PMC2360755_fig2_21359.jpg | What stands out most in this visual? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21353.jpg | What object or scene is depicted here? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21355.jpg | What is being portrayed in this visual content? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21356.jpg | What is being portrayed in this visual content? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21352.jpg | What is the principal component of this image? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21357.jpg | What is the main focus of this visual representation? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360755_fig2_21350.jpg | What is being portrayed in this visual content? | Tumour vascular destructive effect and haemorrhagic necrosis upon Hi-based ILP. Pictures of representative tumour histology (HE) and vascular destruction (CD31) right after ILP with DXR, Hi or DXR + Hi are shown. Orange bar on × 16 magnification pictures corresponds to 100 μm and red bar on × 40 magnification to 50 μm. |
PMC2360773_fig4_21361.jpg | What is the central feature of this picture? | CT scan of thoracic cavity of a patient with refractory HD before and after i.v. vorinostat 600 mg m−2 for 5 days every 3 weeks. |
PMC2360773_fig4_21360.jpg | What object or scene is depicted here? | CT scan of thoracic cavity of a patient with refractory HD before and after i.v. vorinostat 600 mg m−2 for 5 days every 3 weeks. |
PMC2360773_fig5_21363.jpg | What is being portrayed in this visual content? | Resolution of a gastrohepatic mass in a patient with transformed DLBCL following oral vorinostat therapy. CT scans were taken before treatment and after one and two cycles of oral vorinostat. |
PMC2360773_fig5_21364.jpg | What is the focal point of this photograph? | Resolution of a gastrohepatic mass in a patient with transformed DLBCL following oral vorinostat therapy. CT scans were taken before treatment and after one and two cycles of oral vorinostat. |
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