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PMC2361144_fig2_21367.jpg
Can you identify the primary element in this image?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig2_21373.jpg
What is the central feature of this picture?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig2_21369.jpg
Describe the main subject of this image.
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig2_21371.jpg
What is the central feature of this picture?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig2_21368.jpg
What is the central feature of this picture?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig2_21366.jpg
What is the dominant medical problem in this image?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The images labeled MET 1 and 2 were captured at autopsy and show metastases in the liver.
PMC2361144_fig4_21376.jpg
What does this image primarily show?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The mouse was treated with BPD-mediated PDT on day 9.
PMC2361144_fig4_21375.jpg
What is shown in this image?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The mouse was treated with BPD-mediated PDT on day 9.
PMC2361144_fig4_21374.jpg
What is the focal point of this photograph?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The mouse was treated with BPD-mediated PDT on day 9.
PMC2361144_fig4_21379.jpg
What can you see in this picture?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The mouse was treated with BPD-mediated PDT on day 9.
PMC2361144_fig4_21377.jpg
What does this image primarily show?
Series of in vivo fluorescence images of a RIF-1 EGFP tumour growing in the leg of a C3H mouse. The mouse was treated with BPD-mediated PDT on day 9.
PMC2361145_fig2_21381.jpg
What is the central feature of this picture?
Example of a bad prognosis tumour showing EMV but CRM−ve (Group 2). Axial T2-weighted image showing tumour extending into an extramural vein; the distance of tumour to the potential circumferential margins, however, is >1 mm, so the margins are considered safe.
PMC2361223_fig1_21383.jpg
What's the most prominent thing you notice in this picture?
CCL19 mediates potent antitumour responses in a murine model of spontaneous lung cancer. Three-month-old CC-10 TAg mice were injected with CCL19 (0.5μg injection−1) or the same concentration of murine serum albumin in the axillary lymph node region three times a week for 4 weeks. H&E staining of paraffin-embedded lung ...
PMC2361223_fig1_21385.jpg
What is shown in this image?
CCL19 mediates potent antitumour responses in a murine model of spontaneous lung cancer. Three-month-old CC-10 TAg mice were injected with CCL19 (0.5μg injection−1) or the same concentration of murine serum albumin in the axillary lymph node region three times a week for 4 weeks. H&E staining of paraffin-embedded lung ...
PMC2361250_fig5_21386.jpg
What key item or scene is captured in this photo?
Primary cultures of GIST cells. Primary cultures of GISTs showed a homogeneous population of spindle-shaped cells (primary culture of GIST 70810, original magnification × 400).
PMC2361256_fig3_21387.jpg
What can you see in this picture?
Immunohistochemistry on lymph nodes containing carcinomatous cells detected after HES staining (right) after incubation with an anticytokeratin monoclonal antibody (left) (final magnification × 400).
PMC2361276_fig1_21390.jpg
What is the core subject represented in this visual?
Abdomen T2-weighted MRI of day +220 after NST showing liver disease progression (upper images). Partial disease remission on day +288 after the addition of paclitaxel to trastuzumab (lower images).
PMC2361276_fig1_21389.jpg
What is the core subject represented in this visual?
Abdomen T2-weighted MRI of day +220 after NST showing liver disease progression (upper images). Partial disease remission on day +288 after the addition of paclitaxel to trastuzumab (lower images).
PMC2361281_fig4_21396.jpg
What stands out most in this visual?
Image set showing a T1 (A) and T2 (B)-weighted image, demonstrating the tumour and the planned dynamic slice position (white line). Image (C) is the post contrast S0 image. The dynamic contrast enhancement series is represented by a precontrast (D), and early and late contrast enhanced images (E and F). The inset image...
PMC2361281_fig4_21395.jpg
What can you see in this picture?
Image set showing a T1 (A) and T2 (B)-weighted image, demonstrating the tumour and the planned dynamic slice position (white line). Image (C) is the post contrast S0 image. The dynamic contrast enhancement series is represented by a precontrast (D), and early and late contrast enhanced images (E and F). The inset image...
PMC2361281_fig4_21391.jpg
What's the most prominent thing you notice in this picture?
Image set showing a T1 (A) and T2 (B)-weighted image, demonstrating the tumour and the planned dynamic slice position (white line). Image (C) is the post contrast S0 image. The dynamic contrast enhancement series is represented by a precontrast (D), and early and late contrast enhanced images (E and F). The inset image...
PMC2361281_fig4_21393.jpg
What's the most prominent thing you notice in this picture?
Image set showing a T1 (A) and T2 (B)-weighted image, demonstrating the tumour and the planned dynamic slice position (white line). Image (C) is the post contrast S0 image. The dynamic contrast enhancement series is represented by a precontrast (D), and early and late contrast enhanced images (E and F). The inset image...
PMC2361281_fig4_21392.jpg
What is the main focus of this visual representation?
Image set showing a T1 (A) and T2 (B)-weighted image, demonstrating the tumour and the planned dynamic slice position (white line). Image (C) is the post contrast S0 image. The dynamic contrast enhancement series is represented by a precontrast (D), and early and late contrast enhanced images (E and F). The inset image...
PMC2361306_fig1_21401.jpg
What is the main focus of this visual representation?
Overview of the histological and immunohistochemical stainings on consecutive slides, used to differentiate between BVI (upper row: A, B and C) and LVI (lower row: D, E and F). Tumour cell emboli are indicated with black arrows. A and D: HE staining showing the presence of vascular invasion. B and E: On CD34 staining, ...
PMC2361306_fig1_21404.jpg
What is the core subject represented in this visual?
Overview of the histological and immunohistochemical stainings on consecutive slides, used to differentiate between BVI (upper row: A, B and C) and LVI (lower row: D, E and F). Tumour cell emboli are indicated with black arrows. A and D: HE staining showing the presence of vascular invasion. B and E: On CD34 staining, ...
PMC2361306_fig1_21402.jpg
What is the central feature of this picture?
Overview of the histological and immunohistochemical stainings on consecutive slides, used to differentiate between BVI (upper row: A, B and C) and LVI (lower row: D, E and F). Tumour cell emboli are indicated with black arrows. A and D: HE staining showing the presence of vascular invasion. B and E: On CD34 staining, ...
PMC2361306_fig1_21400.jpg
What is the dominant medical problem in this image?
Overview of the histological and immunohistochemical stainings on consecutive slides, used to differentiate between BVI (upper row: A, B and C) and LVI (lower row: D, E and F). Tumour cell emboli are indicated with black arrows. A and D: HE staining showing the presence of vascular invasion. B and E: On CD34 staining, ...
PMC2361306_fig1_21403.jpg
What is the core subject represented in this visual?
Overview of the histological and immunohistochemical stainings on consecutive slides, used to differentiate between BVI (upper row: A, B and C) and LVI (lower row: D, E and F). Tumour cell emboli are indicated with black arrows. A and D: HE staining showing the presence of vascular invasion. B and E: On CD34 staining, ...
PMC2361319_fig3_21405.jpg
What key item or scene is captured in this photo?
Immunocytochemistry of V5-His-tagged PIF transiently transfected into HuH7 cells in the pcDNA3.1+V5His PIF vector. Following transfection, cells were treated with the inhibitor of glycoprotein secretion monensin, fixed and co-stained with an FITC-labelled anti-V5His secondary and Hoescht 33258. FITC fluorescence was no...
PMC2361332_fig3_21406.jpg
What's the most prominent thing you notice in this picture?
FICTION analysis of ACN/IFN-γ paraffin-embedded sections. (A) ACN/IFN-γ sections hybridised with the murine Cot-1 probe. The murine cell line TAP-1 hybridised with the Cot-1 probe is shown in the inset. (B) Identification of microvessel of mouse origin with anti-mouse CD34 (green) and a Cot-1 probe (red). (C) Human met...
PMC2361332_fig3_21409.jpg
What is the principal component of this image?
FICTION analysis of ACN/IFN-γ paraffin-embedded sections. (A) ACN/IFN-γ sections hybridised with the murine Cot-1 probe. The murine cell line TAP-1 hybridised with the Cot-1 probe is shown in the inset. (B) Identification of microvessel of mouse origin with anti-mouse CD34 (green) and a Cot-1 probe (red). (C) Human met...
PMC2361341_fig4_21424.jpg
Describe the main subject of this image.
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21415.jpg
What is the central feature of this picture?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21421.jpg
What object or scene is depicted here?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21423.jpg
Can you identify the primary element in this image?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21418.jpg
Can you identify the primary element in this image?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21412.jpg
What does this image primarily show?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21410.jpg
What is shown in this image?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21425.jpg
What is the focal point of this photograph?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21416.jpg
What is the main focus of this visual representation?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21420.jpg
Describe the main subject of this image.
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21422.jpg
What key item or scene is captured in this photo?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361341_fig4_21413.jpg
What stands out most in this visual?
Subcellular localization of GAGE proteins in cancer cell lines. MAb M4 reacted with GAGE in melanoma MZ2-MEL cells (A–H), exhibiting weak cytoplasmic staining of all cells and strong (E–H) or no (A–D) staining of nuclei. A similar staining pattern was observed for breast cancer cell line BrCa-MZ01-A7 (I–L), but only ab...
PMC2361369_fig2_21426.jpg
What stands out most in this visual?
Fluorescent micrographs show EMT-6 cells treated with (A) doxorubicin (3.5 μM), (B) the fluorescent pH indicator LysoSensor Yellow/Blue DND-160 which accumulates in acidic organelles, (C) doxorubicin and chloroquine 100 μM and (D) doxorubicin and omeprazole 1 mM. Note decrease in fluorescence in endosomes due to doxoru...
PMC2361369_fig2_21429.jpg
What is shown in this image?
Fluorescent micrographs show EMT-6 cells treated with (A) doxorubicin (3.5 μM), (B) the fluorescent pH indicator LysoSensor Yellow/Blue DND-160 which accumulates in acidic organelles, (C) doxorubicin and chloroquine 100 μM and (D) doxorubicin and omeprazole 1 mM. Note decrease in fluorescence in endosomes due to doxoru...
PMC2361372_fig2_21432.jpg
What is the dominant medical problem in this image?
Formazan staining of the tumour tissues from oxykine- and gliadin-treated mice after perfusion with nitroblue tetrazolium (NBT). Tumours were perfused with or without NBT (1 mg ml−1), which was followed by wash with Hank's balanced salt solution to remove unreacted NBT (A). The tumour tissues were fixed with zinc/forma...
PMC2361372_fig2_21430.jpg
What is shown in this image?
Formazan staining of the tumour tissues from oxykine- and gliadin-treated mice after perfusion with nitroblue tetrazolium (NBT). Tumours were perfused with or without NBT (1 mg ml−1), which was followed by wash with Hank's balanced salt solution to remove unreacted NBT (A). The tumour tissues were fixed with zinc/forma...
PMC2361404_fig1_21433.jpg
What is the main focus of this visual representation?
In breast cancer biopsies, ERβ2/βcx immunostatus did not parallel that of ERβ1. Results from two patients before therapy are shown. Note that in patient A, the level of expression of ERβ1≫ERβ2/βcx, whereas in patient B, ERβ1&lt⩽ERβ2/βcx. Magnifications × 40.
PMC2361404_fig1_21435.jpg
What stands out most in this visual?
In breast cancer biopsies, ERβ2/βcx immunostatus did not parallel that of ERβ1. Results from two patients before therapy are shown. Note that in patient A, the level of expression of ERβ1≫ERβ2/βcx, whereas in patient B, ERβ1&lt⩽ERβ2/βcx. Magnifications × 40.
PMC2361404_fig1_21434.jpg
What is shown in this image?
In breast cancer biopsies, ERβ2/βcx immunostatus did not parallel that of ERβ1. Results from two patients before therapy are shown. Note that in patient A, the level of expression of ERβ1≫ERβ2/βcx, whereas in patient B, ERβ1&lt⩽ERβ2/βcx. Magnifications × 40.
PMC2361439_fig1_21439.jpg
What's the most prominent thing you notice in this picture?
Merlin differentially controls the membrane distribution of EGFR in mammalian vs insect cells. (A) Mosaic culture of wild-type mouse epithelial cells surrounding a clone of Nf2-deficient cells marked with a green fluorescent protein-expressing adenovirus (green). Upon stimulation (30 min), fluorescent EGF (Texas Red co...
PMC2361439_fig1_21437.jpg
What is the principal component of this image?
Merlin differentially controls the membrane distribution of EGFR in mammalian vs insect cells. (A) Mosaic culture of wild-type mouse epithelial cells surrounding a clone of Nf2-deficient cells marked with a green fluorescent protein-expressing adenovirus (green). Upon stimulation (30 min), fluorescent EGF (Texas Red co...
PMC2361439_fig1_21438.jpg
What stands out most in this visual?
Merlin differentially controls the membrane distribution of EGFR in mammalian vs insect cells. (A) Mosaic culture of wild-type mouse epithelial cells surrounding a clone of Nf2-deficient cells marked with a green fluorescent protein-expressing adenovirus (green). Upon stimulation (30 min), fluorescent EGF (Texas Red co...
PMC2361457_fig1_21440.jpg
What is the focal point of this photograph?
Representative immunostains of VEGF (A) and EGFR (B) from pretreatment rectal tumour biopsies.
PMC2361457_fig1_21441.jpg
What is the central feature of this picture?
Representative immunostains of VEGF (A) and EGFR (B) from pretreatment rectal tumour biopsies.
PMC2361481_fig3_21443.jpg
What stands out most in this visual?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21452.jpg
What is the focal point of this photograph?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21453.jpg
What does this image primarily show?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21451.jpg
What is the central feature of this picture?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21449.jpg
What is the focal point of this photograph?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21442.jpg
What does this image primarily show?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21448.jpg
What is shown in this image?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21445.jpg
What is shown in this image?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361481_fig3_21444.jpg
What is the principal component of this image?
Immunohistochemical analysis of expression and cellular distribution of pendrin in normal and pathological thyroid tissues. (A) Normal thyroid tissue; the apical staining is heterogeneous inside and between follicles (original magnification × 400; inset – peptide competition test control); (B) immunostaining for pendri...
PMC2361489_fig2_21454.jpg
What is the focal point of this photograph?
Representative example of high-level expression of Rad51 in lung squamous cell lung carcinoma at magnification 10 × 40. Detection of Rad51 protein by immunohistochemistry using the monoclonal anti-Rad51 antibody 1G8 (Buchhop et al, 1996); counterstaining with Hemalum; red arrows mark tumour cells expressing high levels...
PMC2361490_fig1_21456.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous s...
PMC2361490_fig1_21455.jpg
What is the central feature of this picture?
Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous s...
PMC2361490_fig1_21457.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous s...
PMC2361490_fig1_21458.jpg
What object or scene is depicted here?
Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous s...
PMC2361490_fig1_21460.jpg
What key item or scene is captured in this photo?
Immunohistochemical expression of carcinogenesis factors in SCCO: (A) p53 intense nuclear staining, HESx100, (B) EGFR intense membranous staining, HES × 200, (C) VEGF expression: cytoplasmic staining, more intense in cancer cells (♣) than in smooth muscle cells (▴), HES × 200; (D) HER-2 complete and strong membranous s...
PMC2361508_fig1_21471.jpg
What is the central feature of this picture?
Digital image capture of PpIX-stimulated red fluorescence in tumours of three mammary tumour-bearing transgenic strains 1 h following in vivo administration of 200 mg kg−1 ALA, with corresponding H&E stained histological sections. (A, B) Red fluorescence in a papillary adenocarcinoma of a WapTag1 female (77 weeks) (20 ...
PMC2361508_fig1_21473.jpg
What key item or scene is captured in this photo?
Digital image capture of PpIX-stimulated red fluorescence in tumours of three mammary tumour-bearing transgenic strains 1 h following in vivo administration of 200 mg kg−1 ALA, with corresponding H&E stained histological sections. (A, B) Red fluorescence in a papillary adenocarcinoma of a WapTag1 female (77 weeks) (20 ...
PMC2361508_fig1_21469.jpg
What is shown in this image?
Digital image capture of PpIX-stimulated red fluorescence in tumours of three mammary tumour-bearing transgenic strains 1 h following in vivo administration of 200 mg kg−1 ALA, with corresponding H&E stained histological sections. (A, B) Red fluorescence in a papillary adenocarcinoma of a WapTag1 female (77 weeks) (20 ...
PMC2361508_fig1_21468.jpg
What is the core subject represented in this visual?
Digital image capture of PpIX-stimulated red fluorescence in tumours of three mammary tumour-bearing transgenic strains 1 h following in vivo administration of 200 mg kg−1 ALA, with corresponding H&E stained histological sections. (A, B) Red fluorescence in a papillary adenocarcinoma of a WapTag1 female (77 weeks) (20 ...
PMC2361508_fig2_21467.jpg
What key item or scene is captured in this photo?
Photographic image of PpIX-stimulated red fluorescence in a metastatic tumour derived from a PyVT strain female (15 weeks) 1 h following 200 mg kg−1 ALA administration. (A) Brightfield image of isolated bronchial tree. (B) Red fluorescence detection of a metastatic tumour in the lung (arrow). (C) Representative H&E sta...
PMC2361508_fig2_21465.jpg
What is the dominant medical problem in this image?
Photographic image of PpIX-stimulated red fluorescence in a metastatic tumour derived from a PyVT strain female (15 weeks) 1 h following 200 mg kg−1 ALA administration. (A) Brightfield image of isolated bronchial tree. (B) Red fluorescence detection of a metastatic tumour in the lung (arrow). (C) Representative H&E sta...
PMC2361508_fig2_21466.jpg
What key item or scene is captured in this photo?
Photographic image of PpIX-stimulated red fluorescence in a metastatic tumour derived from a PyVT strain female (15 weeks) 1 h following 200 mg kg−1 ALA administration. (A) Brightfield image of isolated bronchial tree. (B) Red fluorescence detection of a metastatic tumour in the lung (arrow). (C) Representative H&E sta...
PMC2361508_fig3_21463.jpg
What is the principal component of this image?
Digital image capture of PpIX-stimulated red fluorescence in early DCIS lesions of two WapTag1 females (41 and 45 weeks) 1 h following in vivo administration of 200 mg kg−1 ALA. (A, C) Red fluorescence detection of DCIS in the mammary gland. In (A) The white arrow indicates the region of DCIS, and the black arrow indic...
PMC2361508_fig3_21464.jpg
What is the focal point of this photograph?
Digital image capture of PpIX-stimulated red fluorescence in early DCIS lesions of two WapTag1 females (41 and 45 weeks) 1 h following in vivo administration of 200 mg kg−1 ALA. (A, C) Red fluorescence detection of DCIS in the mammary gland. In (A) The white arrow indicates the region of DCIS, and the black arrow indic...
PMC2361508_fig3_21461.jpg
What object or scene is depicted here?
Digital image capture of PpIX-stimulated red fluorescence in early DCIS lesions of two WapTag1 females (41 and 45 weeks) 1 h following in vivo administration of 200 mg kg−1 ALA. (A, C) Red fluorescence detection of DCIS in the mammary gland. In (A) The white arrow indicates the region of DCIS, and the black arrow indic...
PMC2361509_fig1_21481.jpg
What does this image primarily show?
Upper panels. Immnunohistochemical stain for p65 in prostate cancer tissues. (A) Prostate cancer staining with the antibody to NF-κB/p65 (C-20, sc-372, Santa Cruz) dilution 1 : 180, magnification × 400. (B) Immunoreactivity was blocked by preabsortion of the primary antibody with the antigen peptide (sc-372 P, Santa Cr...
PMC2361509_fig1_21479.jpg
Can you identify the primary element in this image?
Upper panels. Immnunohistochemical stain for p65 in prostate cancer tissues. (A) Prostate cancer staining with the antibody to NF-κB/p65 (C-20, sc-372, Santa Cruz) dilution 1 : 180, magnification × 400. (B) Immunoreactivity was blocked by preabsortion of the primary antibody with the antigen peptide (sc-372 P, Santa Cr...
PMC2361509_fig1_21478.jpg
What's the most prominent thing you notice in this picture?
Upper panels. Immnunohistochemical stain for p65 in prostate cancer tissues. (A) Prostate cancer staining with the antibody to NF-κB/p65 (C-20, sc-372, Santa Cruz) dilution 1 : 180, magnification × 400. (B) Immunoreactivity was blocked by preabsortion of the primary antibody with the antigen peptide (sc-372 P, Santa Cr...
PMC2361509_fig2_21475.jpg
Can you identify the primary element in this image?
Patterns of NF-κB immunoreactivity in prostate tissues (diaminobenzidine with hematoxylin counterstaining; magnification, × 400). (A) Cells of normal prostate glands with weak cytoplasmic NF-κB staining while nuclear NF-κB staining was only seen in scattered basal cells (arrows). (B) High-grade prostate intraepithelial...
PMC2361509_fig2_21474.jpg
Can you identify the primary element in this image?
Patterns of NF-κB immunoreactivity in prostate tissues (diaminobenzidine with hematoxylin counterstaining; magnification, × 400). (A) Cells of normal prostate glands with weak cytoplasmic NF-κB staining while nuclear NF-κB staining was only seen in scattered basal cells (arrows). (B) High-grade prostate intraepithelial...
PMC2361509_fig2_21477.jpg
What is the dominant medical problem in this image?
Patterns of NF-κB immunoreactivity in prostate tissues (diaminobenzidine with hematoxylin counterstaining; magnification, × 400). (A) Cells of normal prostate glands with weak cytoplasmic NF-κB staining while nuclear NF-κB staining was only seen in scattered basal cells (arrows). (B) High-grade prostate intraepithelial...
PMC2361510_fig2_21484.jpg
What is the core subject represented in this visual?
Immunohistochemical localisation of voltage-gated Na+ channel (VGSC) protein expression in human lung tissues, using a commercial pan-VGSC antibody. (A and B) SCLC, (C and D), normal lung epithelia. Voltage-gated Na+ channel immunoreactivity showed marked upregulation in SCLC (B vs D). Left hand panels (A and C) repres...
PMC2361510_fig2_21482.jpg
What is being portrayed in this visual content?
Immunohistochemical localisation of voltage-gated Na+ channel (VGSC) protein expression in human lung tissues, using a commercial pan-VGSC antibody. (A and B) SCLC, (C and D), normal lung epithelia. Voltage-gated Na+ channel immunoreactivity showed marked upregulation in SCLC (B vs D). Left hand panels (A and C) repres...
PMC2361510_fig2_21483.jpg
What is the core subject represented in this visual?
Immunohistochemical localisation of voltage-gated Na+ channel (VGSC) protein expression in human lung tissues, using a commercial pan-VGSC antibody. (A and B) SCLC, (C and D), normal lung epithelia. Voltage-gated Na+ channel immunoreactivity showed marked upregulation in SCLC (B vs D). Left hand panels (A and C) repres...
PMC2361511_fig2_21489.jpg
What is the central feature of this picture?
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361511_fig2_21488.jpg
What is the principal component of this image?
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361511_fig2_21490.jpg
What is the principal component of this image?
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361511_fig2_21491.jpg
What is shown in this image?
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361511_fig2_21487.jpg
What is the focal point of this photograph?
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361511_fig2_21486.jpg
Describe the main subject of this image.
Immunostaining of primary and metastatic papillary thyroid carcinoma cells with anti-S100A4 polyclonal antibody from the same patient. Weak cytoplasmic labelling of papillary thyroid carcinoma cells in the central portion of the tumour at the magnifications × 100 (A) and × 200 (D). Strong cytoplasmic labelling of carci...
PMC2361582_fig2_21501.jpg
What is being portrayed in this visual content?
Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c...
PMC2361582_fig2_21496.jpg
What key item or scene is captured in this photo?
Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c...
PMC2361582_fig2_21498.jpg
What is the main focus of this visual representation?
Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c...
PMC2361582_fig2_21499.jpg
What is the main focus of this visual representation?
Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c...
PMC2361582_fig2_21497.jpg
Describe the main subject of this image.
Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c...