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PMC2361582_fig2_21493.jpg | What is the main focus of this visual representation? | Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c... |
PMC2361582_fig2_21492.jpg | What is shown in this image? | Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c... |
PMC2361582_fig2_21500.jpg | What is being portrayed in this visual content? | Analysis of sections obtained from a Checkerboard TMA. (A) Serial sections (× 20) from a single biopsy specimen that contained both cancer (thin arrow) and prostatic intra-epithelial neoplasia (PIN) (arrowhead) stained by H&E, PSA, CAM 5.2 and LP34. (B) Serial sections (× 20) of second biopsy specimen containing both c... |
PMC2361594_fig3_21504.jpg | What stands out most in this visual? | Immunohistochemical analysis of IFNAR2 expression in HCC tissues. The intensity of IFNAR2 was scored in a scale from 0 to 2; 0 representing no or faint staining (A); 1=moderate staining (B); and 2=strong staining (C). The latter level of staining was used as an inner control (arrow) within the sample, which was designa... |
PMC2361594_fig3_21502.jpg | What is shown in this image? | Immunohistochemical analysis of IFNAR2 expression in HCC tissues. The intensity of IFNAR2 was scored in a scale from 0 to 2; 0 representing no or faint staining (A); 1=moderate staining (B); and 2=strong staining (C). The latter level of staining was used as an inner control (arrow) within the sample, which was designa... |
PMC2361666_fig3_21505.jpg | What is the central feature of this picture? | Axial FAME series MRI images, 1 min post IV gadolinium contrast. (A) Before HIFU with a right hepatic metastasis within segment VIII showing central necrosis, and (B) 12 days after HIFU, a larger zone consistent with coagulation necrosis within the metastasis. |
PMC2361666_fig4_21507.jpg | Describe the main subject of this image. | Subtraction MRI films, taking the FAME precontrast series from the 1 min postcontrast images. Patient with a right primary renal tumour (A) before HIFU showing contrast uptake within the target tumour, and (B) 12 days after HIFU, showing no contrast uptake within the target tumour, consistent with ablation. |
PMC2361720_ppat-1000065-g001_21520.jpg | What object or scene is depicted here? | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g001_21519.jpg | What is the dominant medical problem in this image? | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g001_21517.jpg | What is the principal component of this image? | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g001_21516.jpg | Describe the main subject of this image. | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g001_21518.jpg | What is the central feature of this picture? | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g001_21515.jpg | What does this image primarily show? | Live-cell imaging of GFP-tagged capsid viruses in differentiated PC12 cells.Cells were grown on glass-bottom MatTek dishes coated with poly-DL-ornithine and natural mouse laminin prior to imaging on a Leica SP5 confocal microscope. Each frame of the movie, a 2D projection representing a stack of 15 images that are 0.5 ... |
PMC2361720_ppat-1000065-g006_21510.jpg | What's the most prominent thing you notice in this picture? | Localization of Us9-TfR in the absence and presence of infection.(A) PK15 cells were transfected with plasmids expressing GFP, Us9-GFP, and Us9-TfR-GFP. Cells were fixed with 4% paraformaldehyde at 24 hours post-transfection, and the nuclei stained with Hoechst 33342 (blue). Direct fluorescence was visualized using an ... |
PMC2361720_ppat-1000065-g006_21512.jpg | What is the main focus of this visual representation? | Localization of Us9-TfR in the absence and presence of infection.(A) PK15 cells were transfected with plasmids expressing GFP, Us9-GFP, and Us9-TfR-GFP. Cells were fixed with 4% paraformaldehyde at 24 hours post-transfection, and the nuclei stained with Hoechst 33342 (blue). Direct fluorescence was visualized using an ... |
PMC2361720_ppat-1000065-g006_21513.jpg | What is the focal point of this photograph? | Localization of Us9-TfR in the absence and presence of infection.(A) PK15 cells were transfected with plasmids expressing GFP, Us9-GFP, and Us9-TfR-GFP. Cells were fixed with 4% paraformaldehyde at 24 hours post-transfection, and the nuclei stained with Hoechst 33342 (blue). Direct fluorescence was visualized using an ... |
PMC2361720_ppat-1000065-g006_21511.jpg | What stands out most in this visual? | Localization of Us9-TfR in the absence and presence of infection.(A) PK15 cells were transfected with plasmids expressing GFP, Us9-GFP, and Us9-TfR-GFP. Cells were fixed with 4% paraformaldehyde at 24 hours post-transfection, and the nuclei stained with Hoechst 33342 (blue). Direct fluorescence was visualized using an ... |
PMC2361752_fig1_21521.jpg | What can you see in this picture? | Immunohistochemical expression of VEGF, HIF-1α and HIF-2α by WHO-stage 1 (A, C, E and F) and WHO-stage 4 (B, D) PETs. (A, B) VEGF is highly expressed in a WHO stage-1 PET (A) and negative in a WHO-stage 4 PET (B). (C, D) HIF-1α cytoplasmic expression is strong in a WHO-stage 1 PET (C). HIF-1α nuclear expression is dete... |
PMC2361752_fig1_21525.jpg | What is the focal point of this photograph? | Immunohistochemical expression of VEGF, HIF-1α and HIF-2α by WHO-stage 1 (A, C, E and F) and WHO-stage 4 (B, D) PETs. (A, B) VEGF is highly expressed in a WHO stage-1 PET (A) and negative in a WHO-stage 4 PET (B). (C, D) HIF-1α cytoplasmic expression is strong in a WHO-stage 1 PET (C). HIF-1α nuclear expression is dete... |
PMC2361752_fig1_21524.jpg | What does this image primarily show? | Immunohistochemical expression of VEGF, HIF-1α and HIF-2α by WHO-stage 1 (A, C, E and F) and WHO-stage 4 (B, D) PETs. (A, B) VEGF is highly expressed in a WHO stage-1 PET (A) and negative in a WHO-stage 4 PET (B). (C, D) HIF-1α cytoplasmic expression is strong in a WHO-stage 1 PET (C). HIF-1α nuclear expression is dete... |
PMC2361752_fig1_21522.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical expression of VEGF, HIF-1α and HIF-2α by WHO-stage 1 (A, C, E and F) and WHO-stage 4 (B, D) PETs. (A, B) VEGF is highly expressed in a WHO stage-1 PET (A) and negative in a WHO-stage 4 PET (B). (C, D) HIF-1α cytoplasmic expression is strong in a WHO-stage 1 PET (C). HIF-1α nuclear expression is dete... |
PMC2361752_fig1_21526.jpg | What is the core subject represented in this visual? | Immunohistochemical expression of VEGF, HIF-1α and HIF-2α by WHO-stage 1 (A, C, E and F) and WHO-stage 4 (B, D) PETs. (A, B) VEGF is highly expressed in a WHO stage-1 PET (A) and negative in a WHO-stage 4 PET (B). (C, D) HIF-1α cytoplasmic expression is strong in a WHO-stage 1 PET (C). HIF-1α nuclear expression is dete... |
PMC2361752_fig5_21531.jpg | What is the dominant medical problem in this image? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361752_fig5_21530.jpg | What can you see in this picture? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361752_fig5_21529.jpg | What is the core subject represented in this visual? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361752_fig5_21528.jpg | What is shown in this image? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361752_fig5_21527.jpg | What is the principal component of this image? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361752_fig5_21532.jpg | What is being portrayed in this visual content? | Immunohistochemical expression of CA9 and CD34 by WHO-stage 1 (A, B) and WHO-stage 4 (C, D) pancreatic endocrine tumours and by VHL cases (E, F). (A, C, E) CA9 is not detected in most well-differentiated PETs (A). Its expression is strong and membranous around areas of necrosis in WHO-stage 4 PETs (C) and cytoplasmic d... |
PMC2361756_fig3_21545.jpg | What is the main focus of this visual representation? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21546.jpg | What key item or scene is captured in this photo? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21535.jpg | What can you see in this picture? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21544.jpg | What is the core subject represented in this visual? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21540.jpg | What is the principal component of this image? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21539.jpg | What is shown in this image? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21538.jpg | What is the dominant medical problem in this image? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21543.jpg | Describe the main subject of this image. | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361756_fig3_21542.jpg | What is the dominant medical problem in this image? | Identification of the expressing cell types by ISH. In situ hybridisation was performed with antisense and control sense (inserted images) RNA probes. Expression is shown for three genes: KIT (A–D), HLXB9 (E–H), and the IMAGE clone number 260215 (I–M). KIT was highly expressed in CIS cells (A) and in SEM (C), and prese... |
PMC2361760_fig2_21534.jpg | What is the dominant medical problem in this image? | Isodose distributions contrasting conventional 3D conformal (left) and IMRT (right) prostate treatment plans. The arrows highlight improved conformality to the prostate and seminal vesicles and decreased rectal volume receiving high dose with the IMRT plan. |
PMC2361773_fig2_21547.jpg | What is the central feature of this picture? | Immunohistochemical staining of Rab1A. (A) Normal tongue epithelium tissue shows weak expression of Rab1A protein. (B) Rab1A-positive case of TLP. The immunoreaction is slightly enhanced in the basal layer. (C) TSCC tissue shows strong cytoplasmic staining of the tumour cells. Original magnification, × 40. Bar=100 μm. |
PMC2361773_fig2_21548.jpg | What is the central feature of this picture? | Immunohistochemical staining of Rab1A. (A) Normal tongue epithelium tissue shows weak expression of Rab1A protein. (B) Rab1A-positive case of TLP. The immunoreaction is slightly enhanced in the basal layer. (C) TSCC tissue shows strong cytoplasmic staining of the tumour cells. Original magnification, × 40. Bar=100 μm. |
PMC2361773_fig2_21549.jpg | What is shown in this image? | Immunohistochemical staining of Rab1A. (A) Normal tongue epithelium tissue shows weak expression of Rab1A protein. (B) Rab1A-positive case of TLP. The immunoreaction is slightly enhanced in the basal layer. (C) TSCC tissue shows strong cytoplasmic staining of the tumour cells. Original magnification, × 40. Bar=100 μm. |
PMC2361782_fig2_21553.jpg | What is the principal component of this image? | Distribution of AlPcS2a in tumours after i.p. injection of 10 mg kg−1 AlPcS2a. Upper photos (fluorescence and H&E staining): 6 h after injection, AlPcS2a is mainly in the tumour vasculature. Lower photos (fluorescence and H&E staining): 48 h after injection, AlPcS2a is mainly intracellular. |
PMC2361782_fig2_21551.jpg | What is the focal point of this photograph? | Distribution of AlPcS2a in tumours after i.p. injection of 10 mg kg−1 AlPcS2a. Upper photos (fluorescence and H&E staining): 6 h after injection, AlPcS2a is mainly in the tumour vasculature. Lower photos (fluorescence and H&E staining): 48 h after injection, AlPcS2a is mainly intracellular. |
PMC2361782_fig2_21550.jpg | What is the dominant medical problem in this image? | Distribution of AlPcS2a in tumours after i.p. injection of 10 mg kg−1 AlPcS2a. Upper photos (fluorescence and H&E staining): 6 h after injection, AlPcS2a is mainly in the tumour vasculature. Lower photos (fluorescence and H&E staining): 48 h after injection, AlPcS2a is mainly intracellular. |
PMC2361784_fig1_21554.jpg | What is the dominant medical problem in this image? | Expression of Ksp-cadherin in foetal kidney. (A) Kidney-specific cadherin mRNA expression was studied by RT–PCR analysis with total RNA derived from human embryonic kidneys at 6th, 9th and 12th week's gestation. Kidney-specific cadherin mRNA expression first arises in the 9th week of pregnancy. (B) The micrograph shows... |
PMC2361784_fig2_21556.jpg | What is the central feature of this picture? | Expression of Ksp-cadherin in adult kidney. The micrographs show immunofluorescence staining with PNA lectin (PNA) and of Ksp-cadherin (cadherin-16) in normal adult kidney tissue of RCC patient 11. The section was counterstained with DAPI to visualise the cell nuclei and the tubules (merge). Ksp-cadherin is present in ... |
PMC2361784_fig2_21557.jpg | What is shown in this image? | Expression of Ksp-cadherin in adult kidney. The micrographs show immunofluorescence staining with PNA lectin (PNA) and of Ksp-cadherin (cadherin-16) in normal adult kidney tissue of RCC patient 11. The section was counterstained with DAPI to visualise the cell nuclei and the tubules (merge). Ksp-cadherin is present in ... |
PMC2361784_fig2_21558.jpg | What is being portrayed in this visual content? | Expression of Ksp-cadherin in adult kidney. The micrographs show immunofluorescence staining with PNA lectin (PNA) and of Ksp-cadherin (cadherin-16) in normal adult kidney tissue of RCC patient 11. The section was counterstained with DAPI to visualise the cell nuclei and the tubules (merge). Ksp-cadherin is present in ... |
PMC2361838_fig1_21560.jpg | What can you see in this picture? | Macroscopic and microscopic features of HCC showing a NIN appearance. (A) Macroscopically, the solitary tumour was separated into an outer nodule and an inner nodule by a septum. (B) Microscopically, the outer nodule showed a moderately differentiated HCC, forming in a pseudoglandular fashion. (C) Hepatocellular carcin... |
PMC2361838_fig1_21559.jpg | What is the focal point of this photograph? | Macroscopic and microscopic features of HCC showing a NIN appearance. (A) Macroscopically, the solitary tumour was separated into an outer nodule and an inner nodule by a septum. (B) Microscopically, the outer nodule showed a moderately differentiated HCC, forming in a pseudoglandular fashion. (C) Hepatocellular carcin... |
PMC2361838_fig1_21561.jpg | Describe the main subject of this image. | Macroscopic and microscopic features of HCC showing a NIN appearance. (A) Macroscopically, the solitary tumour was separated into an outer nodule and an inner nodule by a septum. (B) Microscopically, the outer nodule showed a moderately differentiated HCC, forming in a pseudoglandular fashion. (C) Hepatocellular carcin... |
PMC2361842_fig1_21564.jpg | Describe the main subject of this image. | Multiplanar imaging based on a 3D-US volume data set during ultrasound-guided 14-gauge automated core biopsy proves that needle has transversed mass as central hit. |
PMC2361842_fig1_21562.jpg | What's the most prominent thing you notice in this picture? | Multiplanar imaging based on a 3D-US volume data set during ultrasound-guided 14-gauge automated core biopsy proves that needle has transversed mass as central hit. |
PMC2361842_fig1_21563.jpg | What is the central feature of this picture? | Multiplanar imaging based on a 3D-US volume data set during ultrasound-guided 14-gauge automated core biopsy proves that needle has transversed mass as central hit. |
PMC2361857_fig2_21569.jpg | Can you identify the primary element in this image? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21566.jpg | What stands out most in this visual? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21575.jpg | What is the central feature of this picture? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21568.jpg | What's the most prominent thing you notice in this picture? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21565.jpg | Can you identify the primary element in this image? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21572.jpg | What is the dominant medical problem in this image? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21570.jpg | What is shown in this image? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21567.jpg | What stands out most in this visual? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361857_fig2_21571.jpg | What is the dominant medical problem in this image? | Anti-NP1 and anti-KDR peptide binding. Tumour and endothelial cells were incubated with 5-(6)-carboxyfluorescein-labelled anti-NP1 and anti-KDR peptides on chamber slides for 18 h. Peptide binding to the VEGF receptors, NP-1 and KDR, was examined on 4T1 (A), MDA-MB-231 (B) and HUVEC (C) cells by confocal microscopy (× ... |
PMC2361862_fig2_21576.jpg | What is shown in this image? | Centrosome staining of fine-needle aspiration biopsies of genomically stable (gs) breast lesions. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. The fibroadenoma (A) shows no centrosome aberrations, that is, two centrosomes (red) per nucleus (blue). gs diploid (B, C) and gs aneuploid (D) ca... |
PMC2361862_fig2_21579.jpg | What is being portrayed in this visual content? | Centrosome staining of fine-needle aspiration biopsies of genomically stable (gs) breast lesions. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. The fibroadenoma (A) shows no centrosome aberrations, that is, two centrosomes (red) per nucleus (blue). gs diploid (B, C) and gs aneuploid (D) ca... |
PMC2361862_fig2_21577.jpg | What can you see in this picture? | Centrosome staining of fine-needle aspiration biopsies of genomically stable (gs) breast lesions. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. The fibroadenoma (A) shows no centrosome aberrations, that is, two centrosomes (red) per nucleus (blue). gs diploid (B, C) and gs aneuploid (D) ca... |
PMC2361862_fig3_21580.jpg | Describe the main subject of this image. | Centrosome staining of fine-needle aspiration biopsies of genomically unstable (gu) aneuploid breast carcinomas. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. gu aneuploid carcinomas (A–C) demonstrate a high range of supernumerary centrosomes (red spots). Centrosomes are more often of larg... |
PMC2361862_fig3_21582.jpg | What is being portrayed in this visual content? | Centrosome staining of fine-needle aspiration biopsies of genomically unstable (gu) aneuploid breast carcinomas. Centrosomes are immunostained with a monoclonal antibody against γ-tubulin. gu aneuploid carcinomas (A–C) demonstrate a high range of supernumerary centrosomes (red spots). Centrosomes are more often of larg... |
PMC2361873_fig4_21584.jpg | What is the focal point of this photograph? | Recombinant human endostatin reduces tumour cell adhesion under flow conditions. (A) C26 cells were allowed to adhere to a confluent layer of TNF-α-stimulated HUVECs under flow conditions for 5 min and this was recorded on a videotape. The number of adherent tumour cells per mm2 was determined by off-line analysis of t... |
PMC2361873_fig4_21583.jpg | What is the principal component of this image? | Recombinant human endostatin reduces tumour cell adhesion under flow conditions. (A) C26 cells were allowed to adhere to a confluent layer of TNF-α-stimulated HUVECs under flow conditions for 5 min and this was recorded on a videotape. The number of adherent tumour cells per mm2 was determined by off-line analysis of t... |
PMC2361873_fig4_21587.jpg | What is being portrayed in this visual content? | Recombinant human endostatin reduces tumour cell adhesion under flow conditions. (A) C26 cells were allowed to adhere to a confluent layer of TNF-α-stimulated HUVECs under flow conditions for 5 min and this was recorded on a videotape. The number of adherent tumour cells per mm2 was determined by off-line analysis of t... |
PMC2361873_fig4_21590.jpg | What is being portrayed in this visual content? | Recombinant human endostatin reduces tumour cell adhesion under flow conditions. (A) C26 cells were allowed to adhere to a confluent layer of TNF-α-stimulated HUVECs under flow conditions for 5 min and this was recorded on a videotape. The number of adherent tumour cells per mm2 was determined by off-line analysis of t... |
PMC2361873_fig4_21588.jpg | What is the principal component of this image? | Recombinant human endostatin reduces tumour cell adhesion under flow conditions. (A) C26 cells were allowed to adhere to a confluent layer of TNF-α-stimulated HUVECs under flow conditions for 5 min and this was recorded on a videotape. The number of adherent tumour cells per mm2 was determined by off-line analysis of t... |
PMC2361882_fig1_21593.jpg | What key item or scene is captured in this photo? | Immunodetection of HCMV with anti-IE1 (E13) antibody in a patient with acute colitis (peroxidase, × 500). |
PMC2361882_fig1_21592.jpg | What is the central feature of this picture? | Immunodetection of HCMV with anti-IE1 (E13) antibody in a patient with acute colitis (peroxidase, × 500). |
PMC2361916_fig3_21597.jpg | What does this image primarily show? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361916_fig3_21599.jpg | What is being portrayed in this visual content? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361916_fig3_21598.jpg | What can you see in this picture? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361916_fig3_21596.jpg | What is the core subject represented in this visual? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361916_fig3_21594.jpg | What is being portrayed in this visual content? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361916_fig3_21595.jpg | What is the main focus of this visual representation? | Panel of immunohistochemistry microphotographs showing a biopsy for BM (A) with positive CD1a dendritic elements between epithelial cells (B), as well as positive epithelial cells at the level of metaplastic glands (C). By contrast, CD1a was absent in dysplastic (D) and neoplastic (E) glands as well as in normal gastri... |
PMC2361924_fig3_21602.jpg | What is being portrayed in this visual content? | Immunostaining for SPARC in normal and malignant lung tissues. (A) Weak to moderate expression (1–2+) of SPARC by bronchial epithelium. Most of the staining is present in the apical surface of ciliated surface cells. (B) Bronchioli showed negative (0) expression. (C) Strong (3+) reactivity for SPARC in adenocarcinoma c... |
PMC2361924_fig3_21601.jpg | What is the dominant medical problem in this image? | Immunostaining for SPARC in normal and malignant lung tissues. (A) Weak to moderate expression (1–2+) of SPARC by bronchial epithelium. Most of the staining is present in the apical surface of ciliated surface cells. (B) Bronchioli showed negative (0) expression. (C) Strong (3+) reactivity for SPARC in adenocarcinoma c... |
PMC2361924_fig3_21600.jpg | What is the dominant medical problem in this image? | Immunostaining for SPARC in normal and malignant lung tissues. (A) Weak to moderate expression (1–2+) of SPARC by bronchial epithelium. Most of the staining is present in the apical surface of ciliated surface cells. (B) Bronchioli showed negative (0) expression. (C) Strong (3+) reactivity for SPARC in adenocarcinoma c... |
PMC2361926_fig1_21604.jpg | Describe the main subject of this image. | A 50-year-old male with squamous cell carcinoma of the tongue. (A) Multiple intensity projection 18F-FDG PET image. (B) Sagittal and (C) transaxial images show abnormal uptake in the right cervical region and right premolar area; dental pathology is present (yellow arrow). (D) CT transaxial section reveals level II enl... |
PMC2361926_fig1_21607.jpg | What is the main focus of this visual representation? | A 50-year-old male with squamous cell carcinoma of the tongue. (A) Multiple intensity projection 18F-FDG PET image. (B) Sagittal and (C) transaxial images show abnormal uptake in the right cervical region and right premolar area; dental pathology is present (yellow arrow). (D) CT transaxial section reveals level II enl... |
PMC2361926_fig1_21606.jpg | What is the focal point of this photograph? | A 50-year-old male with squamous cell carcinoma of the tongue. (A) Multiple intensity projection 18F-FDG PET image. (B) Sagittal and (C) transaxial images show abnormal uptake in the right cervical region and right premolar area; dental pathology is present (yellow arrow). (D) CT transaxial section reveals level II enl... |
PMC2361926_fig2_21613.jpg | What is the principal component of this image? | A 42-year-old male with squamous cell carcinoma of tongue. (A) 18F-FDG PET/CT multiple intensity projection image shows the primary site (red arrow) with bilateral cervical nodes (blue arrows). (B) Sagittal and (C) transaxial images show abnormal uptake in the known primary (posterior part of the tongue) and both cervi... |
PMC2361926_fig2_21609.jpg | What object or scene is depicted here? | A 42-year-old male with squamous cell carcinoma of tongue. (A) 18F-FDG PET/CT multiple intensity projection image shows the primary site (red arrow) with bilateral cervical nodes (blue arrows). (B) Sagittal and (C) transaxial images show abnormal uptake in the known primary (posterior part of the tongue) and both cervi... |
PMC2361926_fig2_21612.jpg | What is being portrayed in this visual content? | A 42-year-old male with squamous cell carcinoma of tongue. (A) 18F-FDG PET/CT multiple intensity projection image shows the primary site (red arrow) with bilateral cervical nodes (blue arrows). (B) Sagittal and (C) transaxial images show abnormal uptake in the known primary (posterior part of the tongue) and both cervi... |
PMC2361935_fig7_21614.jpg | What is being portrayed in this visual content? | Representative results of immunohistochemistry against CD34 in the xenograft inoculated on the mice. Microvessels in the control group have a thicker wall with wider diameter (A) than that of the gefitinib-treated group (B). Both images are shown at × 400 magnification originally. |
PMC2361935_fig7_21615.jpg | Describe the main subject of this image. | Representative results of immunohistochemistry against CD34 in the xenograft inoculated on the mice. Microvessels in the control group have a thicker wall with wider diameter (A) than that of the gefitinib-treated group (B). Both images are shown at × 400 magnification originally. |
PMC2361992_fig3_21617.jpg | What is the focal point of this photograph? | Fas localisation in GLC4 and GLC4-Adr determined with the mouse monoclonal CH11 anti-Fas antibody (Upstate Biotechnology) using confocal laser microscopy. |
PMC2361992_fig3_21616.jpg | What is the focal point of this photograph? | Fas localisation in GLC4 and GLC4-Adr determined with the mouse monoclonal CH11 anti-Fas antibody (Upstate Biotechnology) using confocal laser microscopy. |
PMC2361998_fig5_21623.jpg | What is the main focus of this visual representation? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
PMC2361998_fig5_21621.jpg | What is the main focus of this visual representation? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
PMC2361998_fig5_21624.jpg | What object or scene is depicted here? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
PMC2361998_fig5_21618.jpg | What's the most prominent thing you notice in this picture? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
PMC2361998_fig5_21622.jpg | What can you see in this picture? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
PMC2361998_fig5_21620.jpg | Can you identify the primary element in this image? | Fluorescence photomicrographs of 5 μm RIF-1 mouse tumour sections sampled at 5 min (A), 2 h (B) and 24 h (C) after i.v. injection of 5 mg kg−1 hypericin (red fluorescence) and 5 mg kg−1 DiOC18-labelled lipoproteins (green fluorescence). Overlay pictures show the combination of individual photomicrographs of hypericin i... |
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