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PMC2365560_pone-0002125-g005_21771.jpg | What is the core subject represented in this visual? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21777.jpg | What is the focal point of this photograph? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21783.jpg | What object or scene is depicted here? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21779.jpg | What does this image primarily show? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21780.jpg | What object or scene is depicted here? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21776.jpg | What can you see in this picture? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21774.jpg | Describe the main subject of this image. | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21778.jpg | What's the most prominent thing you notice in this picture? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21781.jpg | What is the central feature of this picture? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21773.jpg | Can you identify the primary element in this image? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365560_pone-0002125-g005_21785.jpg | What does this image primarily show? | Regression of tumors following dual MYC/K-rasG12D-oncogene inactivation.(A) Representative serial µCT images of single and double-oncogene-induced lung tumors following withdrawal of doxycycline for 6 weeks. CR (CCSP-rtTA/TetO-K-rasG12D, n = 11) animals demonstrated rapid tumor regression within ∼2 weeks following inac... |
PMC2365932_F3_21789.jpg | What's the most prominent thing you notice in this picture? | Correlation Histology – Computed tomography. (A). Low magnification histology 225 days after intratracheal AdTGF-β1 administration (10×) corresponding to CT image of axial slice (B) and to area indicated with red arrow in 3D reconstructed lungs from same animal (C). See insert in Fig 1F for higher magnification of same... |
PMC2365965_F3_21790.jpg | What object or scene is depicted here? | Thoraco-abdominal CT scan showing two representative cutaneous metastases (arrows). |
PMC2365966_F1_21792.jpg | What is the focal point of this photograph? | CT scan of the chest. Bronchial wall thickening and dilatation predominantly in the lower lung zones consistent with bronchiectasis can be seen. |
PMC2365966_F1_21791.jpg | What's the most prominent thing you notice in this picture? | CT scan of the chest. Bronchial wall thickening and dilatation predominantly in the lower lung zones consistent with bronchiectasis can be seen. |
PMC2365967_F1_21793.jpg | What is the core subject represented in this visual? | Liver biopsy results consistent with intrahepatic cholestasis. Hematoxylin and eosin stain, magnification ×100. |
PMC2365968_F2_21794.jpg | What stands out most in this visual? | Histological section of the skin biopsy showing mucor hyphae in the vessel wall. and necrotic tissue (H&E × 400). |
PMC2365969_F1_21795.jpg | What is the dominant medical problem in this image? | Multislice computed tomography of the heart demonstrates the coronary artery anomaly with a left-side origin of the right coronary artery. CX, circumflex coronary; LAD, left anterior descending artery; RCA, right coronary artery. The right ventricle has been digitally removed. |
PMC2365969_F2_21796.jpg | Describe the main subject of this image. | Multislice computed tomography of the heart demonstrates the coronary artery anomaly with a left-side origin of the right coronary artery. CX, circumflex coronary; LAD, left anterior descending artery; RCA, right coronary artery. The right ventricle has been digitally removed. |
PMC2366023_fig02_21797.jpg | What is the central feature of this picture? | Immunohistochemistry in Stages I (a,b), IV (c) and V (d) a, A D2-40+ lymphatic vessel is recognized in the interstitium of the lesion with wavy myocardial fibres (Stage I). b, The upper half of the figure shows wavy myocardial fibres which are strongly positive for vascular endothelial growth factor-C (VEGF-C). Cardiom... |
PMC2366023_fig02_21799.jpg | What is the principal component of this image? | Immunohistochemistry in Stages I (a,b), IV (c) and V (d) a, A D2-40+ lymphatic vessel is recognized in the interstitium of the lesion with wavy myocardial fibres (Stage I). b, The upper half of the figure shows wavy myocardial fibres which are strongly positive for vascular endothelial growth factor-C (VEGF-C). Cardiom... |
PMC2366023_fig02_21800.jpg | What is the focal point of this photograph? | Immunohistochemistry in Stages I (a,b), IV (c) and V (d) a, A D2-40+ lymphatic vessel is recognized in the interstitium of the lesion with wavy myocardial fibres (Stage I). b, The upper half of the figure shows wavy myocardial fibres which are strongly positive for vascular endothelial growth factor-C (VEGF-C). Cardiom... |
PMC2366023_fig03_21804.jpg | What is the main focus of this visual representation? | Immunohistochemistry in Stages VI (a) and VII (b–d)a, The upper half of the figure shows the lesion with fibrosis (Stage VI), in which D2-40+ lymphatics are scattered adjacent to the viable cardiomyocytes (the lower half of the figure). Their lumens are dilated. b, In Stage VII, showing scar formation, D2-40+ lymphatic... |
PMC2366023_fig03_21802.jpg | What is shown in this image? | Immunohistochemistry in Stages VI (a) and VII (b–d)a, The upper half of the figure shows the lesion with fibrosis (Stage VI), in which D2-40+ lymphatics are scattered adjacent to the viable cardiomyocytes (the lower half of the figure). Their lumens are dilated. b, In Stage VII, showing scar formation, D2-40+ lymphatic... |
PMC2366049_fig27-1_21805.jpg | What's the most prominent thing you notice in this picture? | Averaged saggital baboon brain PET images of [11C]JHU75528 scans, displayed on aligned MRI images. Lines
cross at the center of left putamen. The images are shown in the same color scale. (A) baseline; (B) blocking with Rimonabant
(1 mg/kg, i.v.). Images display the putamen, frontal, parietal, and occipital cortices, a... |
PMC2366049_fig27-1_21806.jpg | What key item or scene is captured in this photo? | Averaged saggital baboon brain PET images of [11C]JHU75528 scans, displayed on aligned MRI images. Lines
cross at the center of left putamen. The images are shown in the same color scale. (A) baseline; (B) blocking with Rimonabant
(1 mg/kg, i.v.). Images display the putamen, frontal, parietal, and occipital cortices, a... |
PMC2366065_pone-0002167-g002_21811.jpg | What is the main focus of this visual representation? | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g002_21818.jpg | What's the most prominent thing you notice in this picture? | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g002_21814.jpg | What is the dominant medical problem in this image? | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g002_21807.jpg | What is shown in this image? | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g002_21817.jpg | Describe the main subject of this image. | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g002_21808.jpg | Describe the main subject of this image. | Fluorescence in situ hybridization with 45S rDNA as the probe shows that 45S rDNAs (green) are the sites of chromosome lesions in meristematic cells of root tips in diploid Lolium perenne cv. Player.The number of lesion sites varys in different cells from 0 to 6 due to the existence of multiple 45S rDNA sites. The left... |
PMC2366065_pone-0002167-g003_21820.jpg | What does this image primarily show? | Fluorescence in situ hybridization with 45S rDNA as a probe shows that 45S (green) rDNAs are the sites of chromosome lesions in meristematic cells of root tips in tetraploid Lolium multiflorum cv. Top One.A: black layer; B: color image by merging red layers and green layers. Arrows indicate sites. Bar = 5 µm. |
PMC2366065_pone-0002167-g003_21819.jpg | What object or scene is depicted here? | Fluorescence in situ hybridization with 45S rDNA as a probe shows that 45S (green) rDNAs are the sites of chromosome lesions in meristematic cells of root tips in tetraploid Lolium multiflorum cv. Top One.A: black layer; B: color image by merging red layers and green layers. Arrows indicate sites. Bar = 5 µm. |
PMC2366065_pone-0002167-g005_21824.jpg | Describe the main subject of this image. | Chromatin depletion or decondensation occurs at various positions of the 45S rDNA repeat unit.Pictures in the left panel represent three different lesions at various positions in the 45S rDNA region. Arrows indicate lesion sites. Pictures in the right panel are kymograms showing the intensity of the signals for the hyb... |
PMC2366065_pone-0002167-g005_21821.jpg | What is shown in this image? | Chromatin depletion or decondensation occurs at various positions of the 45S rDNA repeat unit.Pictures in the left panel represent three different lesions at various positions in the 45S rDNA region. Arrows indicate lesion sites. Pictures in the right panel are kymograms showing the intensity of the signals for the hyb... |
PMC2366065_pone-0002167-g005_21823.jpg | What is the central feature of this picture? | Chromatin depletion or decondensation occurs at various positions of the 45S rDNA repeat unit.Pictures in the left panel represent three different lesions at various positions in the 45S rDNA region. Arrows indicate lesion sites. Pictures in the right panel are kymograms showing the intensity of the signals for the hyb... |
PMC2366066_pone-0002147-g002_21829.jpg | Can you identify the primary element in this image? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366066_pone-0002147-g002_21827.jpg | What object or scene is depicted here? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366066_pone-0002147-g002_21830.jpg | What's the most prominent thing you notice in this picture? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366066_pone-0002147-g002_21831.jpg | What's the most prominent thing you notice in this picture? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366066_pone-0002147-g002_21832.jpg | What stands out most in this visual? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366066_pone-0002147-g002_21828.jpg | What's the most prominent thing you notice in this picture? | Post-mortem neuropathological findings in Patient D.A: Spongiform changes in the frontal cortex with numerous ballooned neurons (H&E, original magnification 100×); Inserts: Immunohistochemistry of ballooned neurons (αB-Crystalline; 20× and 200×). B: Status spongiosus in the occipital cortex (H&E, 100×). C: Cerebellar c... |
PMC2366067_pone-0002182-g004_21835.jpg | What is the central feature of this picture? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21845.jpg | What key item or scene is captured in this photo? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21837.jpg | What is the focal point of this photograph? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21834.jpg | What stands out most in this visual? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21842.jpg | Describe the main subject of this image. | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21844.jpg | What stands out most in this visual? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21838.jpg | What is being portrayed in this visual content? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21843.jpg | What is the core subject represented in this visual? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21841.jpg | What is the main focus of this visual representation? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21846.jpg | Can you identify the primary element in this image? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21839.jpg | Can you identify the primary element in this image? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366067_pone-0002182-g004_21833.jpg | What's the most prominent thing you notice in this picture? | Confocal microscopy of mouse islets.Isolated islets were cultured for 24 h at a basal glucose concentration of 5 mmol/l (A–C); 5G+palmitate (1 mmol/l) (D–F); 5G+palmitate+rosiglitazone (1 μmol/l) (G–I) or 20G (J–L) and 20G+rosiglitazone (1 μmol/l) (M-O). After the culturing period the islets were double-immunolabelled ... |
PMC2366071_fig1_21847.jpg | What is the principal component of this image? | (a) MRI: tumor growth on right breast area. (b) MRI: myocutaneous flap infiltration. |
PMC2367446_pone-0002165-g001_21849.jpg | What is the principal component of this image? | a Confocal microscopy of islets directly isolated ex vivo from the GK rat. The islets were double-immunolabelled for insulin or glucagon and iNOS and analysed by confocal microscopy. Insulin staining and iNOS staining appear, respectively, as red (A) and green (B) fluorescence. Co-localization of insulin/iNOS is seen a... |
PMC2367446_pone-0002165-g001_21855.jpg | What is the dominant medical problem in this image? | a Confocal microscopy of islets directly isolated ex vivo from the GK rat. The islets were double-immunolabelled for insulin or glucagon and iNOS and analysed by confocal microscopy. Insulin staining and iNOS staining appear, respectively, as red (A) and green (B) fluorescence. Co-localization of insulin/iNOS is seen a... |
PMC2367446_pone-0002165-g001_21850.jpg | What is the dominant medical problem in this image? | a Confocal microscopy of islets directly isolated ex vivo from the GK rat. The islets were double-immunolabelled for insulin or glucagon and iNOS and analysed by confocal microscopy. Insulin staining and iNOS staining appear, respectively, as red (A) and green (B) fluorescence. Co-localization of insulin/iNOS is seen a... |
PMC2367446_pone-0002165-g001_21853.jpg | Describe the main subject of this image. | a Confocal microscopy of islets directly isolated ex vivo from the GK rat. The islets were double-immunolabelled for insulin or glucagon and iNOS and analysed by confocal microscopy. Insulin staining and iNOS staining appear, respectively, as red (A) and green (B) fluorescence. Co-localization of insulin/iNOS is seen a... |
PMC2367446_pone-0002165-g003_21863.jpg | What can you see in this picture? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21861.jpg | What's the most prominent thing you notice in this picture? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21862.jpg | What key item or scene is captured in this photo? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21857.jpg | What is the core subject represented in this visual? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21869.jpg | Can you identify the primary element in this image? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21870.jpg | What is the principal component of this image? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21873.jpg | Describe the main subject of this image. | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21860.jpg | What is the dominant medical problem in this image? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21859.jpg | Can you identify the primary element in this image? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21871.jpg | What is the central feature of this picture? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21858.jpg | What is the focal point of this photograph? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367446_pone-0002165-g003_21864.jpg | What is the core subject represented in this visual? | Confocal microscopy of incubated islets from the GK rat.Isolated islets were incubated for 90 min in the presence of; A, B and C) 3.3 mmol/l glucose; D, E and F) 3.3 mmol/l glucose+100 nmol/l GLP-1; G, H and I) 3.3 mmol/l glucose+100 nmol/l GLP-1+2 µmol/l H-89; J, K and L) 3.3 mmol/l glucose+2 µmol/l H-89; M, N and O) ... |
PMC2367452_pgen-1000073-g007_21876.jpg | What is the central feature of this picture? | Analysis of endothelial cell migration and neovascularization in cultured placental primary arteries.(A, B), (D, E) Arterial sections from heterozygous control and homozygous mutants exhibit robust neovascularization and microvessel formation in vitro. Black boxes denote the sites examined by confocal microscopy to vis... |
PMC2367452_pgen-1000073-g007_21874.jpg | What does this image primarily show? | Analysis of endothelial cell migration and neovascularization in cultured placental primary arteries.(A, B), (D, E) Arterial sections from heterozygous control and homozygous mutants exhibit robust neovascularization and microvessel formation in vitro. Black boxes denote the sites examined by confocal microscopy to vis... |
PMC2367452_pgen-1000073-g007_21878.jpg | What is the principal component of this image? | Analysis of endothelial cell migration and neovascularization in cultured placental primary arteries.(A, B), (D, E) Arterial sections from heterozygous control and homozygous mutants exhibit robust neovascularization and microvessel formation in vitro. Black boxes denote the sites examined by confocal microscopy to vis... |
PMC2367452_pgen-1000073-g007_21879.jpg | What is the central feature of this picture? | Analysis of endothelial cell migration and neovascularization in cultured placental primary arteries.(A, B), (D, E) Arterial sections from heterozygous control and homozygous mutants exhibit robust neovascularization and microvessel formation in vitro. Black boxes denote the sites examined by confocal microscopy to vis... |
PMC2367452_pgen-1000073-g008_21883.jpg | What's the most prominent thing you notice in this picture? | Analysis of ventricular wall thickness in Hoxa13 mutants.(A, B) Analysis of hematoxylin and eosin–stained sections (7 µm) from heterozygous control and homozygous mutant hearts at E14.5 embryos reveal qualitatively thicker ventricular walls in the heterozygous control embryos. RV = right ventricle; LV = left ventricle.... |
PMC2367452_pgen-1000073-g008_21880.jpg | What object or scene is depicted here? | Analysis of ventricular wall thickness in Hoxa13 mutants.(A, B) Analysis of hematoxylin and eosin–stained sections (7 µm) from heterozygous control and homozygous mutant hearts at E14.5 embryos reveal qualitatively thicker ventricular walls in the heterozygous control embryos. RV = right ventricle; LV = left ventricle.... |
PMC2367452_pgen-1000073-g009_21884.jpg | Can you identify the primary element in this image? | TIE-2 and LYVE-1 are co-expressed with HOXA13 in the labyrinth vascular endothelia and exhibit altered expression in E13.5 homozygous mutants.(A, B) Immunohistochemical analysis of TIE2 expression (red signal) in the placental labyrinth reveals reduced levels in E13.5 Hoxa13 homozygous mutants compared to heterozygous ... |
PMC2367452_pgen-1000073-g009_21888.jpg | Describe the main subject of this image. | TIE-2 and LYVE-1 are co-expressed with HOXA13 in the labyrinth vascular endothelia and exhibit altered expression in E13.5 homozygous mutants.(A, B) Immunohistochemical analysis of TIE2 expression (red signal) in the placental labyrinth reveals reduced levels in E13.5 Hoxa13 homozygous mutants compared to heterozygous ... |
PMC2367452_pgen-1000073-g009_21889.jpg | Describe the main subject of this image. | TIE-2 and LYVE-1 are co-expressed with HOXA13 in the labyrinth vascular endothelia and exhibit altered expression in E13.5 homozygous mutants.(A, B) Immunohistochemical analysis of TIE2 expression (red signal) in the placental labyrinth reveals reduced levels in E13.5 Hoxa13 homozygous mutants compared to heterozygous ... |
PMC2367452_pgen-1000073-g009_21886.jpg | What can you see in this picture? | TIE-2 and LYVE-1 are co-expressed with HOXA13 in the labyrinth vascular endothelia and exhibit altered expression in E13.5 homozygous mutants.(A, B) Immunohistochemical analysis of TIE2 expression (red signal) in the placental labyrinth reveals reduced levels in E13.5 Hoxa13 homozygous mutants compared to heterozygous ... |
PMC2367625_F3_21890.jpg | What is being portrayed in this visual content? | Biological Process Annotation Data. This figure is reproduced from Washington Smoak et al [11]. The figure shows micrographs of hearts in 16.5dpc mouse embryos. The figure on the left shows an animal with two functional copies of the Shh gene and the figure on the right shows an animal with no functional copies. Ao and... |
PMC2367657_f1-ehp0116-a00202_21892.jpg | Can you identify the primary element in this image? | Although house dust is known to be a predominant source of exposure to PBDEs, it’s not yet clear which part of the dust these chemicals bind to. The dust pictured above contains pet hair (rust brown), pollen (yellow), plant fibers (green), dead skin cells (light to medium brown), dirt and minerals (orange), textile fib... |
PMC2367657_f1-ehp0116-a00202_21894.jpg | What is the central feature of this picture? | Although house dust is known to be a predominant source of exposure to PBDEs, it’s not yet clear which part of the dust these chemicals bind to. The dust pictured above contains pet hair (rust brown), pollen (yellow), plant fibers (green), dead skin cells (light to medium brown), dirt and minerals (orange), textile fib... |
PMC2367657_f1-ehp0116-a00202_21893.jpg | Can you identify the primary element in this image? | Although house dust is known to be a predominant source of exposure to PBDEs, it’s not yet clear which part of the dust these chemicals bind to. The dust pictured above contains pet hair (rust brown), pollen (yellow), plant fibers (green), dead skin cells (light to medium brown), dirt and minerals (orange), textile fib... |
PMC2373298_F1_21896.jpg | What object or scene is depicted here? | A and B: Magnetic Resonance Images of left thigh. |
PMC2373298_F1_21895.jpg | What key item or scene is captured in this photo? | A and B: Magnetic Resonance Images of left thigh. |
PMC2373302_F2_21897.jpg | What is being portrayed in this visual content? | AP radiograph of the left lower limb with the foot showing two fibulae with multiple metatarsals. |
PMC2373784_F3_21899.jpg | What does this image primarily show? | Preoperative echocardiography. Echocardiographic confirmation of the large mass in the ventricle of left atrium. |
PMC2373794_F2_21932.jpg | What can you see in this picture? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21925.jpg | What key item or scene is captured in this photo? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21920.jpg | What is shown in this image? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21918.jpg | What key item or scene is captured in this photo? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21927.jpg | What is the focal point of this photograph? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21928.jpg | What object or scene is depicted here? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21929.jpg | What can you see in this picture? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21919.jpg | What is the principal component of this image? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21924.jpg | What's the most prominent thing you notice in this picture? | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
PMC2373794_F2_21926.jpg | Describe the main subject of this image. | D2-Gpnmb+ bone marrow suppresses iris depigmentation and anterior chamber enlargement. Representative eyes of the indicated strains and ages are shown. The three left most columns show broad beam illumination to assay for the presence of dispersed pigment within the anterior chamber and iris stromal morphology. The fou... |
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