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PMC2376359_fig6_22460.jpg | What does this image primarily show? | Immunohistochemistry on serial sections of breast, liver, lung and rectum carcinomas with BC4 and ST2146 antibodies. × 20 magnification. |
PMC2376365_fig2_22464.jpg | What is the main focus of this visual representation? | (A,B) Scintigraphy of a patient with an OSCC with (A) and without (B) infiltration of the mandibular bone. Technetium 99m MDP bone scans with planar imaging and SPECT were performed in the course of the staging. No increased activity is visible in (A), but a lesion of the right mandible is seen in (B) (arrow). For the ... |
PMC2376365_fig2_22463.jpg | What is the dominant medical problem in this image? | (A,B) Scintigraphy of a patient with an OSCC with (A) and without (B) infiltration of the mandibular bone. Technetium 99m MDP bone scans with planar imaging and SPECT were performed in the course of the staging. No increased activity is visible in (A), but a lesion of the right mandible is seen in (B) (arrow). For the ... |
PMC2376369_fig1_22466.jpg | What is the principal component of this image? | Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are h... |
PMC2376369_fig1_22469.jpg | What is the central feature of this picture? | Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are h... |
PMC2376369_fig1_22470.jpg | What is the focal point of this photograph? | Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are h... |
PMC2376369_fig1_22468.jpg | Describe the main subject of this image. | Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are h... |
PMC2376369_fig1_22467.jpg | What is the central feature of this picture? | Expression of CA XII in invasive breast tumours. The panels show representative examples of CA XII expression detected by IHC in three invasive ductal carcinomas. The cases were associated with overall IHC scores of 10 (A and B), 100 (C and D), and 225 (E and F) respectively. Panels on the right side (B, D and F) are h... |
PMC2376388_fig1_22472.jpg | Describe the main subject of this image. | Infiltrating tumour cells showing (A) distinct nuclear positivity with polyclonal antibody to survivin (× 200 magnification) and (B) both nuclear and cytoplasmic positivity with antisurvivin antibody (× 400 magnification). |
PMC2376388_fig1_22471.jpg | What is the central feature of this picture? | Infiltrating tumour cells showing (A) distinct nuclear positivity with polyclonal antibody to survivin (× 200 magnification) and (B) both nuclear and cytoplasmic positivity with antisurvivin antibody (× 400 magnification). |
PMC2376774_fig1_22473.jpg | What is the focal point of this photograph? | TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the inter... |
PMC2376774_fig1_22474.jpg | Describe the main subject of this image. | TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the inter... |
PMC2376774_fig1_22478.jpg | What can you see in this picture? | TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the inter... |
PMC2376774_fig1_22477.jpg | What is the focal point of this photograph? | TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the inter... |
PMC2376774_fig1_22476.jpg | What's the most prominent thing you notice in this picture? | TRAIL is a potent inducer of apoptosis in Jurkat cells. Jurkat T lymphoma cells (0.5×106 ml−1) were exposed to the vehicle (A–C) or 40 ng ml−1 rhTRAIL (D–F), processed for TEM, observed, and images taken at the following magnifications: A, D–1800×; B–5000×; C, F–18 000×; and E–7000×; M-mitotic cell; I–cell in the inter... |
PMC2376847_fig3_22484.jpg | What is the principal component of this image? | Immunohistochemical demonstration of the HMGA2 protein expression in surgically resected specimens of non-neoplastic pancreatic tissues and pancreatic carcinomas. (A) Non-neoplastic epithelial cells of the main pancreatic duct. A small proportion of duct epithelial cells show HMGA2 immunoreactivity (arrows). (Mayer's h... |
PMC2376847_fig3_22481.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical demonstration of the HMGA2 protein expression in surgically resected specimens of non-neoplastic pancreatic tissues and pancreatic carcinomas. (A) Non-neoplastic epithelial cells of the main pancreatic duct. A small proportion of duct epithelial cells show HMGA2 immunoreactivity (arrows). (Mayer's h... |
PMC2376847_fig3_22479.jpg | What is the central feature of this picture? | Immunohistochemical demonstration of the HMGA2 protein expression in surgically resected specimens of non-neoplastic pancreatic tissues and pancreatic carcinomas. (A) Non-neoplastic epithelial cells of the main pancreatic duct. A small proportion of duct epithelial cells show HMGA2 immunoreactivity (arrows). (Mayer's h... |
PMC2376847_fig3_22480.jpg | What is shown in this image? | Immunohistochemical demonstration of the HMGA2 protein expression in surgically resected specimens of non-neoplastic pancreatic tissues and pancreatic carcinomas. (A) Non-neoplastic epithelial cells of the main pancreatic duct. A small proportion of duct epithelial cells show HMGA2 immunoreactivity (arrows). (Mayer's h... |
PMC2376852_fig6_22489.jpg | What is the main focus of this visual representation? | Double immunofluorescence staining of β1-integrin plus MMP-2 in A-172 and U-138 cells. β1-integrin and MMP-2 were visualised by confocal scanning microscopy after fixing and staining of cells with the appropriate antibodies. Arrows indicate β1-integrin plus MMP-2 colocalisation within focal adhesion sites in the cell m... |
PMC2376852_fig6_22490.jpg | What can you see in this picture? | Double immunofluorescence staining of β1-integrin plus MMP-2 in A-172 and U-138 cells. β1-integrin and MMP-2 were visualised by confocal scanning microscopy after fixing and staining of cells with the appropriate antibodies. Arrows indicate β1-integrin plus MMP-2 colocalisation within focal adhesion sites in the cell m... |
PMC2376852_fig6_22488.jpg | What key item or scene is captured in this photo? | Double immunofluorescence staining of β1-integrin plus MMP-2 in A-172 and U-138 cells. β1-integrin and MMP-2 were visualised by confocal scanning microscopy after fixing and staining of cells with the appropriate antibodies. Arrows indicate β1-integrin plus MMP-2 colocalisation within focal adhesion sites in the cell m... |
PMC2376852_fig6_22486.jpg | What stands out most in this visual? | Double immunofluorescence staining of β1-integrin plus MMP-2 in A-172 and U-138 cells. β1-integrin and MMP-2 were visualised by confocal scanning microscopy after fixing and staining of cells with the appropriate antibodies. Arrows indicate β1-integrin plus MMP-2 colocalisation within focal adhesion sites in the cell m... |
PMC2376856_fig3_22492.jpg | What is the focal point of this photograph? | Representative IHC staining for HER-2/neu in pancreatic tumours: (A) tumour without detectable expression and (B) tumour with strong expression including intense membrane staining consistent with overexpression of HER-2/neu (× 40, original magnification). |
PMC2376856_fig3_22491.jpg | What is shown in this image? | Representative IHC staining for HER-2/neu in pancreatic tumours: (A) tumour without detectable expression and (B) tumour with strong expression including intense membrane staining consistent with overexpression of HER-2/neu (× 40, original magnification). |
PMC2376856_fig4_22494.jpg | Can you identify the primary element in this image? | Representative IHC staining for phospho-AKT in pancreatic tumours: (A) tumour without detectable expression and (B) tumour with strong expression of phospho-AKT consistent with activation of AKT. Normal pancreatic ducts do not have detectable phospho-AKT (× 40, original magnification). |
PMC2376856_fig4_22493.jpg | What stands out most in this visual? | Representative IHC staining for phospho-AKT in pancreatic tumours: (A) tumour without detectable expression and (B) tumour with strong expression of phospho-AKT consistent with activation of AKT. Normal pancreatic ducts do not have detectable phospho-AKT (× 40, original magnification). |
PMC2376916_fig6_22495.jpg | What key item or scene is captured in this photo? | (A) Fluorescence micrograph of the liver including HCC at 3 h after 500 mg kg−1 ALA administration. The right part of the specimen was illuminated reddish-orange by excitation of blue light. (B) The specimen stained with HE. Histopathological examination revealed the right part to be HCC and the left part to be non-HCC... |
PMC2376916_fig6_22496.jpg | What object or scene is depicted here? | (A) Fluorescence micrograph of the liver including HCC at 3 h after 500 mg kg−1 ALA administration. The right part of the specimen was illuminated reddish-orange by excitation of blue light. (B) The specimen stained with HE. Histopathological examination revealed the right part to be HCC and the left part to be non-HCC... |
PMC2376933_fig1_22498.jpg | Describe the main subject of this image. | HPV-16 E6 in ovarian cancers by ISH, (A) sample no. 990917 and (B) sample no. 990193. The purple blue signals representing the expression of the E6 mRNA are at cytoplasm in the tumour cells. (A, B: original magnification × 100). |
PMC2376933_fig1_22497.jpg | What is the core subject represented in this visual? | HPV-16 E6 in ovarian cancers by ISH, (A) sample no. 990917 and (B) sample no. 990193. The purple blue signals representing the expression of the E6 mRNA are at cytoplasm in the tumour cells. (A, B: original magnification × 100). |
PMC2376933_fig2_22499.jpg | Describe the main subject of this image. | HPV-16 E6 in ovarian cancers by IHC, (A) sample No. 990917 and (B) sample no. 990589. The brown signals representing the expression of the E6 protein are mainly at cytoplasm in the tumour cells. (A, B: original magnification × 100). |
PMC2376938_fig5_22501.jpg | What is shown in this image? | Detection of vessels within the tumour of HEP-2 tumour xenograft: Pecam-1 endothelial immunostaining, magnification × 100. (A) Control group, highly vascularised tumour with thick and large vascular channels. Presence of large vessels located at the periphery of the tumour. (B) Irradiation alone, moderately vascularise... |
PMC2376938_fig5_22502.jpg | What is the central feature of this picture? | Detection of vessels within the tumour of HEP-2 tumour xenograft: Pecam-1 endothelial immunostaining, magnification × 100. (A) Control group, highly vascularised tumour with thick and large vascular channels. Presence of large vessels located at the periphery of the tumour. (B) Irradiation alone, moderately vascularise... |
PMC2376938_fig5_22504.jpg | What is being portrayed in this visual content? | Detection of vessels within the tumour of HEP-2 tumour xenograft: Pecam-1 endothelial immunostaining, magnification × 100. (A) Control group, highly vascularised tumour with thick and large vascular channels. Presence of large vessels located at the periphery of the tumour. (B) Irradiation alone, moderately vascularise... |
PMC2376943_fig1_22513.jpg | What is the central feature of this picture? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22506.jpg | Describe the main subject of this image. | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22512.jpg | What is the core subject represented in this visual? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22515.jpg | What is being portrayed in this visual content? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22508.jpg | What is the dominant medical problem in this image? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22510.jpg | Describe the main subject of this image. | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22507.jpg | What is the principal component of this image? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2376943_fig1_22514.jpg | What does this image primarily show? | Immunohistochemical staining showing the distribution of Mcm-2 (middle panel) and Ki67 (right panel) in normal laryngeal squamous epithelium, abnormal hyperplasia, carcinoma in situ and dysplasia arising in squamous metaplasia affecting respiratory-type epithelium. The haematoxylin & eosin (H&E) appearances are given f... |
PMC2377053_fig1_22519.jpg | What stands out most in this visual? | Pretreatment CT scan (A, B) showed a big nasopharyngeal tumour with intracranial invasion in a patient presenting as multiple cranial nerve palsy. The tumour regressed completely with bony regeneration of the destructed skull base after 10-week neoadjuvant chemotherapy (C, D). |
PMC2377053_fig1_22517.jpg | What is the core subject represented in this visual? | Pretreatment CT scan (A, B) showed a big nasopharyngeal tumour with intracranial invasion in a patient presenting as multiple cranial nerve palsy. The tumour regressed completely with bony regeneration of the destructed skull base after 10-week neoadjuvant chemotherapy (C, D). |
PMC2377053_fig1_22520.jpg | What is the core subject represented in this visual? | Pretreatment CT scan (A, B) showed a big nasopharyngeal tumour with intracranial invasion in a patient presenting as multiple cranial nerve palsy. The tumour regressed completely with bony regeneration of the destructed skull base after 10-week neoadjuvant chemotherapy (C, D). |
PMC2377053_fig1_22518.jpg | What's the most prominent thing you notice in this picture? | Pretreatment CT scan (A, B) showed a big nasopharyngeal tumour with intracranial invasion in a patient presenting as multiple cranial nerve palsy. The tumour regressed completely with bony regeneration of the destructed skull base after 10-week neoadjuvant chemotherapy (C, D). |
PMC2377056_fig3_22523.jpg | What's the most prominent thing you notice in this picture? | Macroscopic and microscopic findings of the kidney metastasis shown in a nude mouse inoculated with α5B2 cells. (A) a nude mouse with the kidney metastasis caused by α5B2 inoculation. The mouse was in supine position and intraperitoneal examination was performed after the laparotomy. An arrowhead shows the metastasis s... |
PMC2377056_fig3_22522.jpg | What does this image primarily show? | Macroscopic and microscopic findings of the kidney metastasis shown in a nude mouse inoculated with α5B2 cells. (A) a nude mouse with the kidney metastasis caused by α5B2 inoculation. The mouse was in supine position and intraperitoneal examination was performed after the laparotomy. An arrowhead shows the metastasis s... |
PMC2377056_fig3_22521.jpg | What is the focal point of this photograph? | Macroscopic and microscopic findings of the kidney metastasis shown in a nude mouse inoculated with α5B2 cells. (A) a nude mouse with the kidney metastasis caused by α5B2 inoculation. The mouse was in supine position and intraperitoneal examination was performed after the laparotomy. An arrowhead shows the metastasis s... |
PMC2377077_fig3_22524.jpg | Can you identify the primary element in this image? | uPA expression in 2 days MDA-MB-231 breast cancer cells inoculation model sections. The sections stained with MAb #394 are positive to uPA Mab (A) while the control sections with no primary antibody are negative to uPA MAb light grey (B). The dark grey colour indicates positive cancer cells. Isolated cells and cell clu... |
PMC2377077_fig3_22525.jpg | What stands out most in this visual? | uPA expression in 2 days MDA-MB-231 breast cancer cells inoculation model sections. The sections stained with MAb #394 are positive to uPA Mab (A) while the control sections with no primary antibody are negative to uPA MAb light grey (B). The dark grey colour indicates positive cancer cells. Isolated cells and cell clu... |
PMC2377108_fig1_22533.jpg | What is being portrayed in this visual content? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22531.jpg | What can you see in this picture? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22529.jpg | What is the central feature of this picture? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22530.jpg | What object or scene is depicted here? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22527.jpg | What is the main focus of this visual representation? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22526.jpg | What's the most prominent thing you notice in this picture? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377108_fig1_22528.jpg | What does this image primarily show? | Immunohistochemical localisation of COX-2, NF-κB and IKKα in normal and malignant colonic epithelia from the same patient. The presence of the immunoreactive protein is indicated by brown staining. (A) Normal and (E) tumour tissue treated with preimmune sera as primary antibody (negative control); (B) normal and (F) tu... |
PMC2377110_fig1_22535.jpg | What object or scene is depicted here? | Chest radiograph prior and post-IPM therapy. |
PMC2377110_fig1_22534.jpg | What can you see in this picture? | Chest radiograph prior and post-IPM therapy. |
PMC2377117_fig5_22540.jpg | What is the core subject represented in this visual? | Morphological changes and reorganisation of actin cytoskeleton on MDA-MB-231 cells treated by zoledronic acid (ZOL). – Comparison with C3 exoenzyme. The actin cytoskeleton of MDA-MB-231 cells was labelled by phalloidin-TRITC and analysed by confocal microscopy. On untreated cells (A), note the actin stress fibres and c... |
PMC2377117_fig5_22539.jpg | What is the focal point of this photograph? | Morphological changes and reorganisation of actin cytoskeleton on MDA-MB-231 cells treated by zoledronic acid (ZOL). – Comparison with C3 exoenzyme. The actin cytoskeleton of MDA-MB-231 cells was labelled by phalloidin-TRITC and analysed by confocal microscopy. On untreated cells (A), note the actin stress fibres and c... |
PMC2377117_fig5_22538.jpg | What is the central feature of this picture? | Morphological changes and reorganisation of actin cytoskeleton on MDA-MB-231 cells treated by zoledronic acid (ZOL). – Comparison with C3 exoenzyme. The actin cytoskeleton of MDA-MB-231 cells was labelled by phalloidin-TRITC and analysed by confocal microscopy. On untreated cells (A), note the actin stress fibres and c... |
PMC2377117_fig5_22537.jpg | What does this image primarily show? | Morphological changes and reorganisation of actin cytoskeleton on MDA-MB-231 cells treated by zoledronic acid (ZOL). – Comparison with C3 exoenzyme. The actin cytoskeleton of MDA-MB-231 cells was labelled by phalloidin-TRITC and analysed by confocal microscopy. On untreated cells (A), note the actin stress fibres and c... |
PMC2377117_fig5_22536.jpg | Can you identify the primary element in this image? | Morphological changes and reorganisation of actin cytoskeleton on MDA-MB-231 cells treated by zoledronic acid (ZOL). – Comparison with C3 exoenzyme. The actin cytoskeleton of MDA-MB-231 cells was labelled by phalloidin-TRITC and analysed by confocal microscopy. On untreated cells (A), note the actin stress fibres and c... |
PMC2377119_fig4_22541.jpg | What is shown in this image? | Calculated T2* maps of (A) control and treated GH3 prolactinomas and (B) control and treated RIF-1 fibrosarcomas acquired as part of the MGRE MRI efficacy study. T2* maps, rather than R2* (=1/T2*) maps, are shown for clarity. Treatment with ZD6126 resulted in an increase in the signal intensity of the T2* maps of both ... |
PMC2377119_fig4_22544.jpg | What does this image primarily show? | Calculated T2* maps of (A) control and treated GH3 prolactinomas and (B) control and treated RIF-1 fibrosarcomas acquired as part of the MGRE MRI efficacy study. T2* maps, rather than R2* (=1/T2*) maps, are shown for clarity. Treatment with ZD6126 resulted in an increase in the signal intensity of the T2* maps of both ... |
PMC2377119_fig4_22542.jpg | What does this image primarily show? | Calculated T2* maps of (A) control and treated GH3 prolactinomas and (B) control and treated RIF-1 fibrosarcomas acquired as part of the MGRE MRI efficacy study. T2* maps, rather than R2* (=1/T2*) maps, are shown for clarity. Treatment with ZD6126 resulted in an increase in the signal intensity of the T2* maps of both ... |
PMC2377119_fig4_22543.jpg | What is the core subject represented in this visual? | Calculated T2* maps of (A) control and treated GH3 prolactinomas and (B) control and treated RIF-1 fibrosarcomas acquired as part of the MGRE MRI efficacy study. T2* maps, rather than R2* (=1/T2*) maps, are shown for clarity. Treatment with ZD6126 resulted in an increase in the signal intensity of the T2* maps of both ... |
PMC2377140_fig1_22550.jpg | Can you identify the primary element in this image? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22548.jpg | What does this image primarily show? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22547.jpg | What is being portrayed in this visual content? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22552.jpg | What can you see in this picture? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22551.jpg | What is being portrayed in this visual content? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22549.jpg | What is the central feature of this picture? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22553.jpg | What is the dominant medical problem in this image? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377140_fig1_22546.jpg | What's the most prominent thing you notice in this picture? | Over-expression of ILK in sporadic colorectal cancers. Panel A: representative case examining ILK expression in the control crypts vs cancerous crypts at a lower magnification (× 100) as well as at a higher magnification (× 200). Panels B–G: three additional representative cases demonstrating enhanced ILK expression in... |
PMC2377175_fig3_22557.jpg | Can you identify the primary element in this image? | (A–D) Neoplastic emboli (asterisks) within vascular channels (arrows) of both squamous cell carcinoma (two tumour nests infiltrating the stroma are also present on the right of the Figure) (A) and adenocarcinomas (B). Tumour emboli are strongly immunoreactive for fascin, even when the remainder tumour is negative for t... |
PMC2377175_fig3_22555.jpg | What is the core subject represented in this visual? | (A–D) Neoplastic emboli (asterisks) within vascular channels (arrows) of both squamous cell carcinoma (two tumour nests infiltrating the stroma are also present on the right of the Figure) (A) and adenocarcinomas (B). Tumour emboli are strongly immunoreactive for fascin, even when the remainder tumour is negative for t... |
PMC2377175_fig3_22556.jpg | Can you identify the primary element in this image? | (A–D) Neoplastic emboli (asterisks) within vascular channels (arrows) of both squamous cell carcinoma (two tumour nests infiltrating the stroma are also present on the right of the Figure) (A) and adenocarcinomas (B). Tumour emboli are strongly immunoreactive for fascin, even when the remainder tumour is negative for t... |
PMC2377175_fig3_22554.jpg | What is the dominant medical problem in this image? | (A–D) Neoplastic emboli (asterisks) within vascular channels (arrows) of both squamous cell carcinoma (two tumour nests infiltrating the stroma are also present on the right of the Figure) (A) and adenocarcinomas (B). Tumour emboli are strongly immunoreactive for fascin, even when the remainder tumour is negative for t... |
PMC2377179_fig3_22561.jpg | What's the most prominent thing you notice in this picture? | (A) HeLa cells subject to arginase treatment for 5 days; virtually no intact cells remain present except for a small clump (arrow) in which a large multinucleate cell is present. (B) Control HeLa cell culture in which no arginase was present for 5 days and has gone to confluence. (C) L1210 cells in a settled suspension... |
PMC2377179_fig3_22558.jpg | Describe the main subject of this image. | (A) HeLa cells subject to arginase treatment for 5 days; virtually no intact cells remain present except for a small clump (arrow) in which a large multinucleate cell is present. (B) Control HeLa cell culture in which no arginase was present for 5 days and has gone to confluence. (C) L1210 cells in a settled suspension... |
PMC2377179_fig3_22559.jpg | What is the focal point of this photograph? | (A) HeLa cells subject to arginase treatment for 5 days; virtually no intact cells remain present except for a small clump (arrow) in which a large multinucleate cell is present. (B) Control HeLa cell culture in which no arginase was present for 5 days and has gone to confluence. (C) L1210 cells in a settled suspension... |
PMC2377179_fig3_22560.jpg | Describe the main subject of this image. | (A) HeLa cells subject to arginase treatment for 5 days; virtually no intact cells remain present except for a small clump (arrow) in which a large multinucleate cell is present. (B) Control HeLa cell culture in which no arginase was present for 5 days and has gone to confluence. (C) L1210 cells in a settled suspension... |
PMC2377251_F4_22563.jpg | What is the core subject represented in this visual? | CT scan of the abdomen showing omental nodularity. |
PMC2377252_F1_22564.jpg | What stands out most in this visual? | 'Unenhanced' computed tomography scan of a brain 4 hours (A) and 24 hours (B) after percutaneous coronary intervention. A) Scan shows high attenuation over the tentorium extending along the falx, over the cerebellar convexities and within the dural sinuses (vein of Galen, straight and transverse sinuses) and smaller ve... |
PMC2377252_F1_22566.jpg | Describe the main subject of this image. | 'Unenhanced' computed tomography scan of a brain 4 hours (A) and 24 hours (B) after percutaneous coronary intervention. A) Scan shows high attenuation over the tentorium extending along the falx, over the cerebellar convexities and within the dural sinuses (vein of Galen, straight and transverse sinuses) and smaller ve... |
PMC2377252_F1_22567.jpg | What's the most prominent thing you notice in this picture? | 'Unenhanced' computed tomography scan of a brain 4 hours (A) and 24 hours (B) after percutaneous coronary intervention. A) Scan shows high attenuation over the tentorium extending along the falx, over the cerebellar convexities and within the dural sinuses (vein of Galen, straight and transverse sinuses) and smaller ve... |
PMC2377252_F1_22565.jpg | What is the dominant medical problem in this image? | 'Unenhanced' computed tomography scan of a brain 4 hours (A) and 24 hours (B) after percutaneous coronary intervention. A) Scan shows high attenuation over the tentorium extending along the falx, over the cerebellar convexities and within the dural sinuses (vein of Galen, straight and transverse sinuses) and smaller ve... |
PMC2377252_F1_22569.jpg | What can you see in this picture? | 'Unenhanced' computed tomography scan of a brain 4 hours (A) and 24 hours (B) after percutaneous coronary intervention. A) Scan shows high attenuation over the tentorium extending along the falx, over the cerebellar convexities and within the dural sinuses (vein of Galen, straight and transverse sinuses) and smaller ve... |
PMC2377264_F3_22570.jpg | Can you identify the primary element in this image? | Mitochondrial perturbation due to overproduction of AtWhy2. A. Activity of mitochondrial respiratory chain complexes in plants with altered expression of atwhy2. BN-PAGE was used to separate membrane protein complexes from crude mitochondrial fraction taken from plants of the indicated genotypes. Activity of the differ... |
PMC2377264_F3_22572.jpg | What object or scene is depicted here? | Mitochondrial perturbation due to overproduction of AtWhy2. A. Activity of mitochondrial respiratory chain complexes in plants with altered expression of atwhy2. BN-PAGE was used to separate membrane protein complexes from crude mitochondrial fraction taken from plants of the indicated genotypes. Activity of the differ... |
PMC2377264_F3_22575.jpg | What key item or scene is captured in this photo? | Mitochondrial perturbation due to overproduction of AtWhy2. A. Activity of mitochondrial respiratory chain complexes in plants with altered expression of atwhy2. BN-PAGE was used to separate membrane protein complexes from crude mitochondrial fraction taken from plants of the indicated genotypes. Activity of the differ... |
PMC2377264_F3_22577.jpg | What is the dominant medical problem in this image? | Mitochondrial perturbation due to overproduction of AtWhy2. A. Activity of mitochondrial respiratory chain complexes in plants with altered expression of atwhy2. BN-PAGE was used to separate membrane protein complexes from crude mitochondrial fraction taken from plants of the indicated genotypes. Activity of the differ... |
PMC2377273_F1_22583.jpg | What is the principal component of this image? | Examples of positive staining of tumoral tissue sections. A) Invasive ductal carcinoma, patient L116. Hematoxylin-eosin stain in 200× magnification reveals poor differentiation with a predominantly solid infiltrative pattern. The nuclei are highly pleomorphic with notable nucleoli. B) Outgrowths of cells from tumor fra... |
PMC2377273_F1_22580.jpg | What is the focal point of this photograph? | Examples of positive staining of tumoral tissue sections. A) Invasive ductal carcinoma, patient L116. Hematoxylin-eosin stain in 200× magnification reveals poor differentiation with a predominantly solid infiltrative pattern. The nuclei are highly pleomorphic with notable nucleoli. B) Outgrowths of cells from tumor fra... |
PMC2377273_F1_22578.jpg | What can you see in this picture? | Examples of positive staining of tumoral tissue sections. A) Invasive ductal carcinoma, patient L116. Hematoxylin-eosin stain in 200× magnification reveals poor differentiation with a predominantly solid infiltrative pattern. The nuclei are highly pleomorphic with notable nucleoli. B) Outgrowths of cells from tumor fra... |
PMC2377273_F1_22581.jpg | What's the most prominent thing you notice in this picture? | Examples of positive staining of tumoral tissue sections. A) Invasive ductal carcinoma, patient L116. Hematoxylin-eosin stain in 200× magnification reveals poor differentiation with a predominantly solid infiltrative pattern. The nuclei are highly pleomorphic with notable nucleoli. B) Outgrowths of cells from tumor fra... |
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