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PMC2377273_F1_22582.jpg | What is the core subject represented in this visual? | Examples of positive staining of tumoral tissue sections. A) Invasive ductal carcinoma, patient L116. Hematoxylin-eosin stain in 200× magnification reveals poor differentiation with a predominantly solid infiltrative pattern. The nuclei are highly pleomorphic with notable nucleoli. B) Outgrowths of cells from tumor fra... |
PMC2377275_F6_22584.jpg | What's the most prominent thing you notice in this picture? | Differential Effects of Iressa on growth and morphology. MAM-1 co-cultures were treated for 24–48 h by replacing conditioned media with fresh media in the absence (Control) or presence of 1 μM Iressa. A. Phase contrast photomicrographs of MAM-1 co-cultures following treatment with 1 μM Iressa were taken using a 10× obj... |
PMC2377334_pone-0002222-g006_22592.jpg | What key item or scene is captured in this photo? | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2377334_pone-0002222-g006_22591.jpg | What is being portrayed in this visual content? | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2377334_pone-0002222-g006_22587.jpg | Describe the main subject of this image. | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2377334_pone-0002222-g006_22595.jpg | What is the principal component of this image? | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2377334_pone-0002222-g006_22589.jpg | What is the focal point of this photograph? | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2377334_pone-0002222-g006_22588.jpg | What's the most prominent thing you notice in this picture? | Confocal microscopic images of HEK 293 cells, treated with QD-TRF conjugate (A, B), MSA-CdTe QDs (C).(B) QDs stained the cells during cell division period. The panel to the left displays the images of CdTe QDs and their corresponding images of HEK 293 cells nuclei stained with Hoechst 33342 are shown in the middle pane... |
PMC2383278_f2_22611.jpg | What can you see in this picture? | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f2_22605.jpg | What's the most prominent thing you notice in this picture? | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f2_22613.jpg | What is the dominant medical problem in this image? | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f2_22609.jpg | What key item or scene is captured in this photo? | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f2_22607.jpg | Describe the main subject of this image. | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f2_22606.jpg | Can you identify the primary element in this image? | Normal and novel interactions after laser tweezers micromanipulation. The left column shows cells immediately after tweezers placement; the middle column, 3 days in vitro; and the right column, 7 days in vitro. A: An example of attraction between a rod cell and a multipolar cell. At 3 days, long filopodial processes em... |
PMC2383278_f6_22602.jpg | What is being portrayed in this visual content? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22597.jpg | What is the central feature of this picture? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22598.jpg | What is the dominant medical problem in this image? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22600.jpg | What is being portrayed in this visual content? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22599.jpg | What does this image primarily show? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22601.jpg | What key item or scene is captured in this photo? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383278_f6_22603.jpg | What is the central feature of this picture? | Photoreceptors change orientation to their target depending on whether there is attraction or repulsion. A: The axonal or nuclear pole of the cell was designated to be 0 degrees. Here a rod photoreceptor, repelled by its target cell, rotated over time so that the nuclear pole faced away from the target cell by seven da... |
PMC2383989_fig2_22617.jpg | What does this image primarily show? | Topographical maps showing scalp distributions of emotional expression effects for upright faces (top) and inverted faces (bottom), obtained by subtracting ERPs to neutral faces from ERPs to fearful faces within six successive post-stimulus latency windows. Red colours indicate an enhanced positivity for fearful relati... |
PMC2383989_fig2_22616.jpg | What can you see in this picture? | Topographical maps showing scalp distributions of emotional expression effects for upright faces (top) and inverted faces (bottom), obtained by subtracting ERPs to neutral faces from ERPs to fearful faces within six successive post-stimulus latency windows. Red colours indicate an enhanced positivity for fearful relati... |
PMC2383989_fig2_22620.jpg | What is the main focus of this visual representation? | Topographical maps showing scalp distributions of emotional expression effects for upright faces (top) and inverted faces (bottom), obtained by subtracting ERPs to neutral faces from ERPs to fearful faces within six successive post-stimulus latency windows. Red colours indicate an enhanced positivity for fearful relati... |
PMC2383989_fig2_22618.jpg | What object or scene is depicted here? | Topographical maps showing scalp distributions of emotional expression effects for upright faces (top) and inverted faces (bottom), obtained by subtracting ERPs to neutral faces from ERPs to fearful faces within six successive post-stimulus latency windows. Red colours indicate an enhanced positivity for fearful relati... |
PMC2383989_fig2_22619.jpg | What is the dominant medical problem in this image? | Topographical maps showing scalp distributions of emotional expression effects for upright faces (top) and inverted faces (bottom), obtained by subtracting ERPs to neutral faces from ERPs to fearful faces within six successive post-stimulus latency windows. Red colours indicate an enhanced positivity for fearful relati... |
PMC2384002_pone-0002315-g005_22627.jpg | What stands out most in this visual? | Mouse DND1 and APOBEC3 co-localize to peri-nuclear sites in the cell cytoplasm.(a) COS7 cells were transfected with expression constructs for GFP-Dnd1 for visualization of green fluorescence due to GFP-DND1. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (d)... |
PMC2384002_pone-0002315-g005_22624.jpg | What is the central feature of this picture? | Mouse DND1 and APOBEC3 co-localize to peri-nuclear sites in the cell cytoplasm.(a) COS7 cells were transfected with expression constructs for GFP-Dnd1 for visualization of green fluorescence due to GFP-DND1. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (d)... |
PMC2384002_pone-0002315-g005_22625.jpg | What is shown in this image? | Mouse DND1 and APOBEC3 co-localize to peri-nuclear sites in the cell cytoplasm.(a) COS7 cells were transfected with expression constructs for GFP-Dnd1 for visualization of green fluorescence due to GFP-DND1. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (d)... |
PMC2384002_pone-0002315-g005_22626.jpg | What is being portrayed in this visual content? | Mouse DND1 and APOBEC3 co-localize to peri-nuclear sites in the cell cytoplasm.(a) COS7 cells were transfected with expression constructs for GFP-Dnd1 for visualization of green fluorescence due to GFP-DND1. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (d)... |
PMC2384002_pone-0002315-g005_22622.jpg | What's the most prominent thing you notice in this picture? | Mouse DND1 and APOBEC3 co-localize to peri-nuclear sites in the cell cytoplasm.(a) COS7 cells were transfected with expression constructs for GFP-Dnd1 for visualization of green fluorescence due to GFP-DND1. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (d)... |
PMC2384002_pone-0002315-g006_22631.jpg | What object or scene is depicted here? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22628.jpg | Describe the main subject of this image. | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22633.jpg | What is the central feature of this picture? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22630.jpg | What is shown in this image? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22632.jpg | What object or scene is depicted here? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22629.jpg | What key item or scene is captured in this photo? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384002_pone-0002315-g006_22634.jpg | What is shown in this image? | Localization of APOBEC3 and DND1 in NIH3T3 and 293T cells.(a–d) Co-transfection of mCherry-Apobec3 and GFP-DND1 expression constructs into NIH3T3 cells. Cells were fixed with 2% paraformaldehyde before visualization of fluorescent signal by confocal microscopy. (a) Red fluorescence due to mCherry-APOBEC3 was imaged usi... |
PMC2384009_pone-0002262-g001_22645.jpg | What is the dominant medical problem in this image? | Membrane structure at immunological synapses in sterol-enriched T cells.Jurkat 8.2 T cells were treated without sterols (control), cholesterol (CH), 2:1 CH:7KC, 1:2 CH:7KC or 7KC alone as described in
Methods
. Sterol-enriched, Laurdan-labeled Jurkat 8.2 cells were conjugated to CMRA-labeled B cells for 7 min in the p... |
PMC2384009_pone-0002262-g001_22641.jpg | What is the core subject represented in this visual? | Membrane structure at immunological synapses in sterol-enriched T cells.Jurkat 8.2 T cells were treated without sterols (control), cholesterol (CH), 2:1 CH:7KC, 1:2 CH:7KC or 7KC alone as described in
Methods
. Sterol-enriched, Laurdan-labeled Jurkat 8.2 cells were conjugated to CMRA-labeled B cells for 7 min in the p... |
PMC2384009_pone-0002262-g001_22636.jpg | What is the central feature of this picture? | Membrane structure at immunological synapses in sterol-enriched T cells.Jurkat 8.2 T cells were treated without sterols (control), cholesterol (CH), 2:1 CH:7KC, 1:2 CH:7KC or 7KC alone as described in
Methods
. Sterol-enriched, Laurdan-labeled Jurkat 8.2 cells were conjugated to CMRA-labeled B cells for 7 min in the p... |
PMC2384009_pone-0002262-g001_22642.jpg | Can you identify the primary element in this image? | Membrane structure at immunological synapses in sterol-enriched T cells.Jurkat 8.2 T cells were treated without sterols (control), cholesterol (CH), 2:1 CH:7KC, 1:2 CH:7KC or 7KC alone as described in
Methods
. Sterol-enriched, Laurdan-labeled Jurkat 8.2 cells were conjugated to CMRA-labeled B cells for 7 min in the p... |
PMC2384009_pone-0002262-g001_22639.jpg | What's the most prominent thing you notice in this picture? | Membrane structure at immunological synapses in sterol-enriched T cells.Jurkat 8.2 T cells were treated without sterols (control), cholesterol (CH), 2:1 CH:7KC, 1:2 CH:7KC or 7KC alone as described in
Methods
. Sterol-enriched, Laurdan-labeled Jurkat 8.2 cells were conjugated to CMRA-labeled B cells for 7 min in the p... |
PMC2384163_fig2_22648.jpg | What object or scene is depicted here? | Analysis of cell cycle characteristics using IdU/BrdU co-labeling. (A) Injection at T0 h with IdU and T1.5 h with BrdU followed by sacrifice at T2.0 h allows identification of three cell types: those within S-phase at T0–1.5 but within G2/M at T1.5–2.0 (Lcells: IdU-labeled only—green in panels B–E); cells entering S-ph... |
PMC2384163_fig2_22649.jpg | What is shown in this image? | Analysis of cell cycle characteristics using IdU/BrdU co-labeling. (A) Injection at T0 h with IdU and T1.5 h with BrdU followed by sacrifice at T2.0 h allows identification of three cell types: those within S-phase at T0–1.5 but within G2/M at T1.5–2.0 (Lcells: IdU-labeled only—green in panels B–E); cells entering S-ph... |
PMC2384163_fig2_22646.jpg | What is the main focus of this visual representation? | Analysis of cell cycle characteristics using IdU/BrdU co-labeling. (A) Injection at T0 h with IdU and T1.5 h with BrdU followed by sacrifice at T2.0 h allows identification of three cell types: those within S-phase at T0–1.5 but within G2/M at T1.5–2.0 (Lcells: IdU-labeled only—green in panels B–E); cells entering S-ph... |
PMC2386057_F3_22651.jpg | What is the core subject represented in this visual? | Expression heat map of 329 differentially expressed transcripts in earthworms exposed to TNT, RDX or TNT+RDX in comparison with the controls (five worms per treatment). Both samples and genes were hierarchically clustered using Euclidean distance and average linkage (see Additional file Additional file 4: Figure S1 and... |
PMC2386120_F1_22653.jpg | What is the focal point of this photograph? | Left breast mammogram showing a lobulated, circumscribed mass with no evidence of malignancy, suggestive of a fibroadenoma. |
PMC2386130_F1_22662.jpg | What is the focal point of this photograph? | Visualization of Cy3 labeled β-Actin dsRNA in unfed adult female Ixodes scapularis ticks: Unfed female adult ticks were injected with Cy3 labeled Actin dsRNA and kept at 37°C overnight. Unfed ticks injected with labeled dsRNA were visualized under confocal microscope. A-B: Control ticks injected with Cy3 dye; C. Cy3 la... |
PMC2386130_F1_22663.jpg | What is the main focus of this visual representation? | Visualization of Cy3 labeled β-Actin dsRNA in unfed adult female Ixodes scapularis ticks: Unfed female adult ticks were injected with Cy3 labeled Actin dsRNA and kept at 37°C overnight. Unfed ticks injected with labeled dsRNA were visualized under confocal microscope. A-B: Control ticks injected with Cy3 dye; C. Cy3 la... |
PMC2386130_F1_22661.jpg | What is the focal point of this photograph? | Visualization of Cy3 labeled β-Actin dsRNA in unfed adult female Ixodes scapularis ticks: Unfed female adult ticks were injected with Cy3 labeled Actin dsRNA and kept at 37°C overnight. Unfed ticks injected with labeled dsRNA were visualized under confocal microscope. A-B: Control ticks injected with Cy3 dye; C. Cy3 la... |
PMC2386130_F1_22660.jpg | Can you identify the primary element in this image? | Visualization of Cy3 labeled β-Actin dsRNA in unfed adult female Ixodes scapularis ticks: Unfed female adult ticks were injected with Cy3 labeled Actin dsRNA and kept at 37°C overnight. Unfed ticks injected with labeled dsRNA were visualized under confocal microscope. A-B: Control ticks injected with Cy3 dye; C. Cy3 la... |
PMC2386130_F2_22659.jpg | What is the focal point of this photograph? | In vivo visualization of Cy3 labeled β-Actin dsRNA: Labeled dsRNA was injected in the unfed adult female ticks and fed for 72 hrs on rabbit. 72 hrs fed ticks were dissected and synganglia were removed and visualized under confocal microscopy. A) light microscopic image of tick synganglia; B) Low infrared image showed a... |
PMC2386130_F2_22654.jpg | What is the core subject represented in this visual? | In vivo visualization of Cy3 labeled β-Actin dsRNA: Labeled dsRNA was injected in the unfed adult female ticks and fed for 72 hrs on rabbit. 72 hrs fed ticks were dissected and synganglia were removed and visualized under confocal microscopy. A) light microscopic image of tick synganglia; B) Low infrared image showed a... |
PMC2386130_F2_22656.jpg | What is the principal component of this image? | In vivo visualization of Cy3 labeled β-Actin dsRNA: Labeled dsRNA was injected in the unfed adult female ticks and fed for 72 hrs on rabbit. 72 hrs fed ticks were dissected and synganglia were removed and visualized under confocal microscopy. A) light microscopic image of tick synganglia; B) Low infrared image showed a... |
PMC2386130_F2_22655.jpg | What is the core subject represented in this visual? | In vivo visualization of Cy3 labeled β-Actin dsRNA: Labeled dsRNA was injected in the unfed adult female ticks and fed for 72 hrs on rabbit. 72 hrs fed ticks were dissected and synganglia were removed and visualized under confocal microscopy. A) light microscopic image of tick synganglia; B) Low infrared image showed a... |
PMC2386130_F2_22657.jpg | What is shown in this image? | In vivo visualization of Cy3 labeled β-Actin dsRNA: Labeled dsRNA was injected in the unfed adult female ticks and fed for 72 hrs on rabbit. 72 hrs fed ticks were dissected and synganglia were removed and visualized under confocal microscopy. A) light microscopic image of tick synganglia; B) Low infrared image showed a... |
PMC2386132_F2_22665.jpg | Can you identify the primary element in this image? | Original biopsy of rectal tumour demonstrating adenocarcinoma. |
PMC2386132_F3_22666.jpg | What is the principal component of this image? | Biopsy of haemorrhoidectomy specimen with adenocarcinoma within anal canal squamous tissue. |
PMC2386264_pone-0002251-g001_22672.jpg | What object or scene is depicted here? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g001_22674.jpg | What is the principal component of this image? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g001_22669.jpg | What is the core subject represented in this visual? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g001_22675.jpg | What is the dominant medical problem in this image? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g001_22673.jpg | What is the main focus of this visual representation? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g001_22671.jpg | What is shown in this image? | Two-dimensional ultrastructure of the HTLV-1 virological synapse.A, B Low-magnification images of single CD4+ T cells and cell-cell conjugates: A, naturally HTLV-1 infected CD4+ T cells (PBMCs); B, non-infected CD4+ T cells. Cell-cell conjugates were significantly more frequent and larger among HTLV-1 infected cells. C... |
PMC2386264_pone-0002251-g002_22668.jpg | What is shown in this image? | Polarization of mitochondria and microtubule organization centre of the HTLV-1 infected cell towards the target cell.A,B Virological synapses (VS) formed between naturally HTLV-1 infected CD4+ T cells (PBMCs) and autologous uninfected CD4+ target cells as shown in Movies S6–S7 and S3, S4, S5, respectively. HTLV-1 parti... |
PMC2386264_pone-0002251-g002_22667.jpg | What is the focal point of this photograph? | Polarization of mitochondria and microtubule organization centre of the HTLV-1 infected cell towards the target cell.A,B Virological synapses (VS) formed between naturally HTLV-1 infected CD4+ T cells (PBMCs) and autologous uninfected CD4+ target cells as shown in Movies S6–S7 and S3, S4, S5, respectively. HTLV-1 parti... |
PMC2386264_pone-0002251-g004_22683.jpg | What's the most prominent thing you notice in this picture? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22687.jpg | What object or scene is depicted here? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22691.jpg | What stands out most in this visual? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22686.jpg | What is the core subject represented in this visual? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22677.jpg | What is the dominant medical problem in this image? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22685.jpg | What does this image primarily show? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22678.jpg | What is being portrayed in this visual content? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22688.jpg | What key item or scene is captured in this photo? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22680.jpg | What stands out most in this visual? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22692.jpg | What does this image primarily show? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22689.jpg | What does this image primarily show? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22679.jpg | What is the core subject represented in this visual? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386264_pone-0002251-g004_22676.jpg | What key item or scene is captured in this photo? | Three-dimensional ultrastructure of the VS: enveloped HTLV-1 virions are trapped in multiple isolated synaptic clefts.Cell-to-cell transmission of HTLV-1 as observed in tomograms of the VS formed between HTLV-1 infected CD4+ T-cell (PBMC) and an autologous uninfected CD4+ T-cell as a target cell. These cells were stain... |
PMC2386454_F2_22694.jpg | What is being portrayed in this visual content? | C. roseus cell suspension cultures. A, Compact callus clusters formed after 3 days of inoculation in the MS liquid medium. B, A dispersed cell suspension culture formed after 6 days of inoculation in the above-mentioned medium. C, Microscopic observation of six-day-old culture: arrows indicate divided cells. D, Fluores... |
PMC2386454_F2_22695.jpg | What is the principal component of this image? | C. roseus cell suspension cultures. A, Compact callus clusters formed after 3 days of inoculation in the MS liquid medium. B, A dispersed cell suspension culture formed after 6 days of inoculation in the above-mentioned medium. C, Microscopic observation of six-day-old culture: arrows indicate divided cells. D, Fluores... |
PMC2386454_F2_22696.jpg | What is being portrayed in this visual content? | C. roseus cell suspension cultures. A, Compact callus clusters formed after 3 days of inoculation in the MS liquid medium. B, A dispersed cell suspension culture formed after 6 days of inoculation in the above-mentioned medium. C, Microscopic observation of six-day-old culture: arrows indicate divided cells. D, Fluores... |
PMC2386458_F5_22698.jpg | What is the central feature of this picture? | Chimeric embryos derived from Rex1 KO ES cells. When HP4-EGFP ES cells, which were homozygotes for the mutant Rex1 allele and marked by the constitutively-active Egfp transgene, were injected into blastocysts, the embryos developed to chimeras at 12.5 dpc in which widespread contributions of GFP-positive cells were obs... |
PMC2386468_F2_22700.jpg | What stands out most in this visual? | Subcellular localization of SAPK4-protein.(A) Nuclear localization of SAPK4-GFP fusion protein in onion epidermal cells. The arrow points to the nucleus. (B) The GFP-derived fluorescence signal of SAPK4-GFP fusion protein was merged with a light microscopic image of the transformed onion epidermal cell. (C) Onion epide... |
PMC2386468_F2_22701.jpg | What is the dominant medical problem in this image? | Subcellular localization of SAPK4-protein.(A) Nuclear localization of SAPK4-GFP fusion protein in onion epidermal cells. The arrow points to the nucleus. (B) The GFP-derived fluorescence signal of SAPK4-GFP fusion protein was merged with a light microscopic image of the transformed onion epidermal cell. (C) Onion epide... |
PMC2386468_F2_22699.jpg | What is the main focus of this visual representation? | Subcellular localization of SAPK4-protein.(A) Nuclear localization of SAPK4-GFP fusion protein in onion epidermal cells. The arrow points to the nucleus. (B) The GFP-derived fluorescence signal of SAPK4-GFP fusion protein was merged with a light microscopic image of the transformed onion epidermal cell. (C) Onion epide... |
PMC2386468_F2_22703.jpg | What stands out most in this visual? | Subcellular localization of SAPK4-protein.(A) Nuclear localization of SAPK4-GFP fusion protein in onion epidermal cells. The arrow points to the nucleus. (B) The GFP-derived fluorescence signal of SAPK4-GFP fusion protein was merged with a light microscopic image of the transformed onion epidermal cell. (C) Onion epide... |
PMC2386468_F2_22702.jpg | What stands out most in this visual? | Subcellular localization of SAPK4-protein.(A) Nuclear localization of SAPK4-GFP fusion protein in onion epidermal cells. The arrow points to the nucleus. (B) The GFP-derived fluorescence signal of SAPK4-GFP fusion protein was merged with a light microscopic image of the transformed onion epidermal cell. (C) Onion epide... |
PMC2386474_F1_22704.jpg | What does this image primarily show? | CT image showing the primary lesion in the right kidney. |
PMC2386476_F1_22705.jpg | What is the central feature of this picture? | Microscopy and Endoscopy pictures at diagnosis in November 2001. a: shows pictures of H and E staining, b: KIT positive staining c: Endoscopic findings. |
PMC2386476_F2_22710.jpg | What key item or scene is captured in this photo? | CT scan images. a: at diagnosis (November 2001) b and c: at the last follow up (in December 2007). |
PMC2386476_F2_22709.jpg | What stands out most in this visual? | CT scan images. a: at diagnosis (November 2001) b and c: at the last follow up (in December 2007). |
PMC2386476_F2_22708.jpg | What is the principal component of this image? | CT scan images. a: at diagnosis (November 2001) b and c: at the last follow up (in December 2007). |
PMC2386477_F3_22713.jpg | What's the most prominent thing you notice in this picture? | GFP localization in the transformed SvH3P strain. Interphase cytoplasmic GFP localization in live and fixed cells, with immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vo... |
PMC2386477_F3_22716.jpg | What is the central feature of this picture? | GFP localization in the transformed SvH3P strain. Interphase cytoplasmic GFP localization in live and fixed cells, with immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vo... |
PMC2386477_F3_22718.jpg | What is the main focus of this visual representation? | GFP localization in the transformed SvH3P strain. Interphase cytoplasmic GFP localization in live and fixed cells, with immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vo... |
PMC2386477_F4_22724.jpg | What is the core subject represented in this visual? | H3::GFP localized to both nuclei in the transformed SvH3G strain. Nuclear localization of H3::GFP and comparative immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; H3::GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vort... |
PMC2386477_F4_22726.jpg | What key item or scene is captured in this photo? | H3::GFP localized to both nuclei in the transformed SvH3G strain. Nuclear localization of H3::GFP and comparative immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; H3::GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vort... |
PMC2386477_F4_22727.jpg | What is the main focus of this visual representation? | H3::GFP localized to both nuclei in the transformed SvH3G strain. Nuclear localization of H3::GFP and comparative immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; H3::GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vort... |
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