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PMC2386477_F4_22723.jpg | What is being portrayed in this visual content? | H3::GFP localized to both nuclei in the transformed SvH3G strain. Nuclear localization of H3::GFP and comparative immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; H3::GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vort... |
PMC2386477_F4_22725.jpg | What stands out most in this visual? | H3::GFP localized to both nuclei in the transformed SvH3G strain. Nuclear localization of H3::GFP and comparative immunolocalization of the microtubule cytoskeleton in S. vortens trophozoites (DAPI, blue; H3::GFP, green; anti-α-tubulin, red). UPPER PANELS: Panel (a) shows the GFP fluorescence of a field of live S. vort... |
PMC2386478_F4_22711.jpg | What is the main focus of this visual representation? | Indirect immunofluorescence staining of intact fixed leptospires. L. interrogans serovar Pomona strain LPF and L. biflexa serovar Patoc strain Patoc 1 were incubated with mouse anti-Lsa21 serum, followed by incubation with a fluorescein isothiocyanate-conjugated goat anti-mouse antibody. Magnification × 1,260. |
PMC2386478_F4_22712.jpg | What stands out most in this visual? | Indirect immunofluorescence staining of intact fixed leptospires. L. interrogans serovar Pomona strain LPF and L. biflexa serovar Patoc strain Patoc 1 were incubated with mouse anti-Lsa21 serum, followed by incubation with a fluorescein isothiocyanate-conjugated goat anti-mouse antibody. Magnification × 1,260. |
PMC2386478_F8_22731.jpg | What can you see in this picture? | (A) Leptospirosis, human liver: Lsa21 is present as red deposits in the cytoplasm of isolated macrophages along the sinusoidal lining (arrow heads). Similar deposits are observed focally on the apical sinusoidal plasma membrane of hepatocytes and as small granules in the underneath cytoplasm (arrows). IHC and light hem... |
PMC2386478_F8_22730.jpg | Can you identify the primary element in this image? | (A) Leptospirosis, human liver: Lsa21 is present as red deposits in the cytoplasm of isolated macrophages along the sinusoidal lining (arrow heads). Similar deposits are observed focally on the apical sinusoidal plasma membrane of hepatocytes and as small granules in the underneath cytoplasm (arrows). IHC and light hem... |
PMC2386478_F8_22729.jpg | What can you see in this picture? | (A) Leptospirosis, human liver: Lsa21 is present as red deposits in the cytoplasm of isolated macrophages along the sinusoidal lining (arrow heads). Similar deposits are observed focally on the apical sinusoidal plasma membrane of hepatocytes and as small granules in the underneath cytoplasm (arrows). IHC and light hem... |
PMC2386496_F4_22732.jpg | What is the focal point of this photograph? | CT scan of a patient with bleeding from the tumor bed. The SIS secured the defect and stopped the bleeding by compressing the defect. |
PMC2386505_f1_22737.jpg | What is the focal point of this photograph? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22738.jpg | What is the dominant medical problem in this image? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22736.jpg | What is the core subject represented in this visual? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22733.jpg | What is the central feature of this picture? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22739.jpg | What is the focal point of this photograph? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22740.jpg | What is being portrayed in this visual content? | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386505_f1_22735.jpg | Describe the main subject of this image. | The photograph of all grading lens at the slit lamp (Haag-Streit BQ 900). The grades are as follows: grade 0, clear; grade 1, clear nuclear with wide sutures; grade 2, slight dense nuclear with opacities radiating from sutures; grade 3, dense nuclear without clefts; grade 4, dense nuclear with clefts; grade 5, nuclear ... |
PMC2386507_f3_22742.jpg | What is the main focus of this visual representation? | Hematoxylin and eosin staining of porcine corneal stroma. The porcine cornea stroma were stained before treatment (A) as well as after incubating for one week in N2 gas (B), in air without freezing (C), or in air after freezing (D). Hematoxylin and eosin staining showed few cellular nuclei in the corneal stroma of the ... |
PMC2386507_f3_22744.jpg | What's the most prominent thing you notice in this picture? | Hematoxylin and eosin staining of porcine corneal stroma. The porcine cornea stroma were stained before treatment (A) as well as after incubating for one week in N2 gas (B), in air without freezing (C), or in air after freezing (D). Hematoxylin and eosin staining showed few cellular nuclei in the corneal stroma of the ... |
PMC2386507_f3_22743.jpg | What is the core subject represented in this visual? | Hematoxylin and eosin staining of porcine corneal stroma. The porcine cornea stroma were stained before treatment (A) as well as after incubating for one week in N2 gas (B), in air without freezing (C), or in air after freezing (D). Hematoxylin and eosin staining showed few cellular nuclei in the corneal stroma of the ... |
PMC2386507_f3_22741.jpg | What key item or scene is captured in this photo? | Hematoxylin and eosin staining of porcine corneal stroma. The porcine cornea stroma were stained before treatment (A) as well as after incubating for one week in N2 gas (B), in air without freezing (C), or in air after freezing (D). Hematoxylin and eosin staining showed few cellular nuclei in the corneal stroma of the ... |
PMC2386507_f4_22745.jpg | What key item or scene is captured in this photo? | The results of the TUNEL assay of porcine corneal stroma. The TUNEL assay before treatment (A) and after incubation in N2 gas for three (B), five (C), and seven (D) days is shown. Cellular nuclei were stained with propidium iodide. Many positively stained nuclei (yellow dots in C) were observed at day 3 whereas no stai... |
PMC2386507_f4_22747.jpg | What can you see in this picture? | The results of the TUNEL assay of porcine corneal stroma. The TUNEL assay before treatment (A) and after incubation in N2 gas for three (B), five (C), and seven (D) days is shown. Cellular nuclei were stained with propidium iodide. Many positively stained nuclei (yellow dots in C) were observed at day 3 whereas no stai... |
PMC2386507_f4_22746.jpg | What is the central feature of this picture? | The results of the TUNEL assay of porcine corneal stroma. The TUNEL assay before treatment (A) and after incubation in N2 gas for three (B), five (C), and seven (D) days is shown. Cellular nuclei were stained with propidium iodide. Many positively stained nuclei (yellow dots in C) were observed at day 3 whereas no stai... |
PMC2386507_f4_22748.jpg | What's the most prominent thing you notice in this picture? | The results of the TUNEL assay of porcine corneal stroma. The TUNEL assay before treatment (A) and after incubation in N2 gas for three (B), five (C), and seven (D) days is shown. Cellular nuclei were stained with propidium iodide. Many positively stained nuclei (yellow dots in C) were observed at day 3 whereas no stai... |
PMC2386509_f1_22751.jpg | What is shown in this image? | Expression of P2X7 receptor on human conjunctival and corneal epithelial cells. Conjunctival cell line (A), corneal cell line (B) and cells from ocular surface impression cytology (C) presented P2X7 receptor expression. Cells were fixed, permeabilized, and then incubated with a P2X7 antibody. Nuclei were stained with p... |
PMC2386509_f1_22749.jpg | What's the most prominent thing you notice in this picture? | Expression of P2X7 receptor on human conjunctival and corneal epithelial cells. Conjunctival cell line (A), corneal cell line (B) and cells from ocular surface impression cytology (C) presented P2X7 receptor expression. Cells were fixed, permeabilized, and then incubated with a P2X7 antibody. Nuclei were stained with p... |
PMC2386509_f1_22750.jpg | What's the most prominent thing you notice in this picture? | Expression of P2X7 receptor on human conjunctival and corneal epithelial cells. Conjunctival cell line (A), corneal cell line (B) and cells from ocular surface impression cytology (C) presented P2X7 receptor expression. Cells were fixed, permeabilized, and then incubated with a P2X7 antibody. Nuclei were stained with p... |
PMC2386549_pone-0002278-g001_22755.jpg | What is the focal point of this photograph? | Meprinβ expression in Wistar rat kidneys.Immunostaining of paraffin embedded kidney tissues from Wistar rats: (A) positive immunofluorescence staining of proximal tubules and (B) of glomeruli using a specific meprinβ antibody. Control immunofluorescence staining: (C) replacement of the primary antibody with normal rabb... |
PMC2386549_pone-0002278-g001_22754.jpg | What is the central feature of this picture? | Meprinβ expression in Wistar rat kidneys.Immunostaining of paraffin embedded kidney tissues from Wistar rats: (A) positive immunofluorescence staining of proximal tubules and (B) of glomeruli using a specific meprinβ antibody. Control immunofluorescence staining: (C) replacement of the primary antibody with normal rabb... |
PMC2386549_pone-0002278-g001_22753.jpg | What object or scene is depicted here? | Meprinβ expression in Wistar rat kidneys.Immunostaining of paraffin embedded kidney tissues from Wistar rats: (A) positive immunofluorescence staining of proximal tubules and (B) of glomeruli using a specific meprinβ antibody. Control immunofluorescence staining: (C) replacement of the primary antibody with normal rabb... |
PMC2386549_pone-0002278-g001_22756.jpg | What is the focal point of this photograph? | Meprinβ expression in Wistar rat kidneys.Immunostaining of paraffin embedded kidney tissues from Wistar rats: (A) positive immunofluorescence staining of proximal tubules and (B) of glomeruli using a specific meprinβ antibody. Control immunofluorescence staining: (C) replacement of the primary antibody with normal rabb... |
PMC2386796_F1_22758.jpg | What object or scene is depicted here? | Chest Radiograph, November 2006. |
PMC2386796_F2_22759.jpg | What does this image primarily show? | Computer Tomography of Thorax, November 2006. |
PMC2386799_F2_22763.jpg | What is the main focus of this visual representation? | Within this single dilated duct is a portion lined by hyperplastic columnar cells (single arrow) and flat epithelial cells of the mucocele-like tumor (double arrow). Hematoxylin and eosin stain, magnification ×200. |
PMC2386799_F2_22762.jpg | What's the most prominent thing you notice in this picture? | Within this single dilated duct is a portion lined by hyperplastic columnar cells (single arrow) and flat epithelial cells of the mucocele-like tumor (double arrow). Hematoxylin and eosin stain, magnification ×200. |
PMC2386799_F3_22761.jpg | What is shown in this image? | Columnar cell lesions with atypia (flat epithelial atypia). Hematoxylin and eosin stain, magnification ×200. |
PMC2386799_F3_22760.jpg | What is the main focus of this visual representation? | Columnar cell lesions with atypia (flat epithelial atypia). Hematoxylin and eosin stain, magnification ×200. |
PMC2386807_F4_22764.jpg | What does this image primarily show? | Tumor-associated collagen signatures. (a)-(c) Example of TACS-1. A region of locally dense collagen (a) near (40 μm 'above') a small tumor region (b) that is within the globally increased collagen region surrounding tumors, resulting from increased SHG (collagen) signal intensity; (c) three-dimensional surface plot of ... |
PMC2386807_F4_22769.jpg | What does this image primarily show? | Tumor-associated collagen signatures. (a)-(c) Example of TACS-1. A region of locally dense collagen (a) near (40 μm 'above') a small tumor region (b) that is within the globally increased collagen region surrounding tumors, resulting from increased SHG (collagen) signal intensity; (c) three-dimensional surface plot of ... |
PMC2386807_F4_22765.jpg | What is the focal point of this photograph? | Tumor-associated collagen signatures. (a)-(c) Example of TACS-1. A region of locally dense collagen (a) near (40 μm 'above') a small tumor region (b) that is within the globally increased collagen region surrounding tumors, resulting from increased SHG (collagen) signal intensity; (c) three-dimensional surface plot of ... |
PMC2386807_F4_22768.jpg | What's the most prominent thing you notice in this picture? | Tumor-associated collagen signatures. (a)-(c) Example of TACS-1. A region of locally dense collagen (a) near (40 μm 'above') a small tumor region (b) that is within the globally increased collagen region surrounding tumors, resulting from increased SHG (collagen) signal intensity; (c) three-dimensional surface plot of ... |
PMC2386807_F6_22777.jpg | What is the principal component of this image? | FLIM an SLIM analysis of mammary tumors. (a) Multiphoton spectral lifetime imaging microscopy (SLIM) analysis of the emission spectrum from endogenous fluorescence resulting from excitation at 890 nm. The emission signals were separated by 10 nm spectral steps over 16 channels (10 channels are displayed) and the photon... |
PMC2386807_F6_22778.jpg | What is the principal component of this image? | FLIM an SLIM analysis of mammary tumors. (a) Multiphoton spectral lifetime imaging microscopy (SLIM) analysis of the emission spectrum from endogenous fluorescence resulting from excitation at 890 nm. The emission signals were separated by 10 nm spectral steps over 16 channels (10 channels are displayed) and the photon... |
PMC2386807_F7_22774.jpg | What does this image primarily show? | Fluorescence lifetime imaging microscopy analysis of invading tumor cells. (a) Intensity and fluorescence lifetime imaging microscopy (FLIM) images of cells away from and near invasive TACS-3 regions showing increased fluorescent intensity and lifetime near invasive regions (left side of images). (b) FLIM images of tum... |
PMC2386807_F7_22771.jpg | What object or scene is depicted here? | Fluorescence lifetime imaging microscopy analysis of invading tumor cells. (a) Intensity and fluorescence lifetime imaging microscopy (FLIM) images of cells away from and near invasive TACS-3 regions showing increased fluorescent intensity and lifetime near invasive regions (left side of images). (b) FLIM images of tum... |
PMC2386807_F7_22770.jpg | What is shown in this image? | Fluorescence lifetime imaging microscopy analysis of invading tumor cells. (a) Intensity and fluorescence lifetime imaging microscopy (FLIM) images of cells away from and near invasive TACS-3 regions showing increased fluorescent intensity and lifetime near invasive regions (left side of images). (b) FLIM images of tum... |
PMC2386818_F7_22783.jpg | What does this image primarily show? | Primary spermatocytes of mutants from Ceprani collection. a-b: primary spermatocytes of ms(2)Fra-1 mutant males immunostained with either T53-1 (a) or S5 (b) antibodies; note that kl-3 loop is fragmented (a), ks-1 (faint fluorescence) is larger and kl-5 loop (bright fluorescence) is smaller than wild type (b); c-d: imm... |
PMC2386818_F7_22782.jpg | What's the most prominent thing you notice in this picture? | Primary spermatocytes of mutants from Ceprani collection. a-b: primary spermatocytes of ms(2)Fra-1 mutant males immunostained with either T53-1 (a) or S5 (b) antibodies; note that kl-3 loop is fragmented (a), ks-1 (faint fluorescence) is larger and kl-5 loop (bright fluorescence) is smaller than wild type (b); c-d: imm... |
PMC2386818_F7_22781.jpg | What is being portrayed in this visual content? | Primary spermatocytes of mutants from Ceprani collection. a-b: primary spermatocytes of ms(2)Fra-1 mutant males immunostained with either T53-1 (a) or S5 (b) antibodies; note that kl-3 loop is fragmented (a), ks-1 (faint fluorescence) is larger and kl-5 loop (bright fluorescence) is smaller than wild type (b); c-d: imm... |
PMC2386826_F4_22785.jpg | Describe the main subject of this image. | MAR-predicted sequence within IGF2 is found in the nuclear matrix. Fluorescence in situ hybridization of a 5 kb IGF2 subclone (red) encompassing sequence predicted to contain a MAR on nuclear halo preparations (counterstained with dapi and shown in black and white). The positive hybridization signals are found only in ... |
PMC2386837_pbio-0060128-g005_22792.jpg | What key item or scene is captured in this photo? | Src64B Is Required for Multiple RTK Pathways during Development(A and B) Src64B is involved in EGFR signaling during oogenesis. (A) Wild-type (WT) eggs have two dorsal appendages arising from the dorsal anterior of the eggshell. The space between these two dorsal appendages represents the dorsal-most cells, which are s... |
PMC2386837_pbio-0060128-g005_22793.jpg | What is being portrayed in this visual content? | Src64B Is Required for Multiple RTK Pathways during Development(A and B) Src64B is involved in EGFR signaling during oogenesis. (A) Wild-type (WT) eggs have two dorsal appendages arising from the dorsal anterior of the eggshell. The space between these two dorsal appendages represents the dorsal-most cells, which are s... |
PMC2386837_pbio-0060128-g005_22788.jpg | What is the principal component of this image? | Src64B Is Required for Multiple RTK Pathways during Development(A and B) Src64B is involved in EGFR signaling during oogenesis. (A) Wild-type (WT) eggs have two dorsal appendages arising from the dorsal anterior of the eggshell. The space between these two dorsal appendages represents the dorsal-most cells, which are s... |
PMC2386837_pbio-0060128-g005_22791.jpg | What can you see in this picture? | Src64B Is Required for Multiple RTK Pathways during Development(A and B) Src64B is involved in EGFR signaling during oogenesis. (A) Wild-type (WT) eggs have two dorsal appendages arising from the dorsal anterior of the eggshell. The space between these two dorsal appendages represents the dorsal-most cells, which are s... |
PMC2386861_F3_22795.jpg | What is the core subject represented in this visual? | Lung consolidations with air bronchograms in posterior lung fields in ARDS (panel A and B). |
PMC2386861_F3_22794.jpg | What does this image primarily show? | Lung consolidations with air bronchograms in posterior lung fields in ARDS (panel A and B). |
PMC2386959_fig01_22796.jpg | What's the most prominent thing you notice in this picture? | Coronal cresyl violet-stained brain sections (moving from rostral to caudal from the top to the bottom of the figure) through the hippocampus for three representative rats with dorsal hippocampal lesions (HL) from each group (isoflurane-lesion and propofol-lesion) and one control rat (CON) from each group. Each column ... |
PMC2387071_pone-0002364-g012_22798.jpg | What is the focal point of this photograph? | Optical microscopy images of d-EAK16 membranes.The colorless membranous structure was formed in phosphate-buffered saline and transferred to a glass slide. It can be seen by the naked eye when stained with Congo red. A) At 100 magnifications, the circular region is the membrane in the water and the rest is the dry memb... |
PMC2387071_pone-0002364-g012_22797.jpg | What does this image primarily show? | Optical microscopy images of d-EAK16 membranes.The colorless membranous structure was formed in phosphate-buffered saline and transferred to a glass slide. It can be seen by the naked eye when stained with Congo red. A) At 100 magnifications, the circular region is the membrane in the water and the rest is the dry memb... |
PMC2387155_F6_22810.jpg | What is the principal component of this image? | Myocardial perfusion CMR was performed in a 43 year-old female to evaluate exertional chest pressure. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrate severe hypoenhancement of the septum, anterior wall, and apex that is not present on resting perfusion imaging (B). Late gadolinium enh... |
PMC2387155_F6_22809.jpg | What is the dominant medical problem in this image? | Myocardial perfusion CMR was performed in a 43 year-old female to evaluate exertional chest pressure. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrate severe hypoenhancement of the septum, anterior wall, and apex that is not present on resting perfusion imaging (B). Late gadolinium enh... |
PMC2387155_F7_22808.jpg | What is the main focus of this visual representation? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22800.jpg | What is shown in this image? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22804.jpg | What is the central feature of this picture? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22806.jpg | What can you see in this picture? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22802.jpg | What key item or scene is captured in this photo? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22803.jpg | What is being portrayed in this visual content? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22801.jpg | What stands out most in this visual? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387155_F7_22805.jpg | What can you see in this picture? | First-pass myocardial perfusion CMR was performed in a 75 year-old male with a history of bypass surgery seeking a second opinion regarding intervention for bypass graft disease. Perfusion images obtained during intravenous infusion of adenosine (A) demonstrates diffuse subendocardial perfusion abnormality not present ... |
PMC2387157_F1_22799.jpg | Can you identify the primary element in this image? | Abdominal computed tomography scan demonstrating intraperitoneal free fluid (arrowhead) and an enlarged, anechoic spleen with hypoechoic areas representing focal necrosis (arrow). |
PMC2387161_F1_22811.jpg | What is the main focus of this visual representation? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22818.jpg | What is shown in this image? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22812.jpg | What is shown in this image? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22813.jpg | What's the most prominent thing you notice in this picture? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22817.jpg | What stands out most in this visual? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22816.jpg | What is the focal point of this photograph? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387161_F1_22815.jpg | What can you see in this picture? | Fluorescence and phase contrast micrographs of S. iniae showing binding of biotinylated fibrinogen. Strains QMA0072, QMA0076 and QMA00141 were incubated with biotinylated human fibrinogen, extensively washed and subsequently labelled with FITC-conjugated streptavidin. In each case panel A) indicates bacteria incubated ... |
PMC2387171_F1_22830.jpg | What is the focal point of this photograph? | Expression of RACK1 mRNA in pig tissues. (A-B) In situ hybridisation autoradiography of RACK1 antisense (A) and sense (B) probes on depigmented sections. For each probe, normal (N) tissues are displayed on the left (skin, lung, liver and lymph node) and tumoral (T) tissues on the right (cutaneous melanoma, metastatic m... |
PMC2387171_F1_22831.jpg | What is the dominant medical problem in this image? | Expression of RACK1 mRNA in pig tissues. (A-B) In situ hybridisation autoradiography of RACK1 antisense (A) and sense (B) probes on depigmented sections. For each probe, normal (N) tissues are displayed on the left (skin, lung, liver and lymph node) and tumoral (T) tissues on the right (cutaneous melanoma, metastatic m... |
PMC2387171_F2_22824.jpg | What is the core subject represented in this visual? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F2_22823.jpg | What is the principal component of this image? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F2_22827.jpg | What is being portrayed in this visual content? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F2_22825.jpg | What is being portrayed in this visual content? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F2_22828.jpg | What can you see in this picture? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F2_22826.jpg | What can you see in this picture? | Identification of melanoma cells from MeLiM by MITF. Melanocytes were visualized as brown nuclear granules, by immunohistochemistry with MITF antibody (A-C) and without the primary antibody (D-F). (A, D) Normal skin. (B, E) Cutaneous melanoma. (C, F) Melanoma metastasis in a lung. a, alveolae; be, bronchiolar epitheliu... |
PMC2387171_F3_22835.jpg | What is the focal point of this photograph? | RACK1 expression in normal pig epidermis. (A, C, D) Confocal microscopy analysis of RACK1 protein (green fluorescence), and double labelling for either MITF (A, C) or DCT (D) (red fluorescence) on pig skin. Normal epidermis were from control Meishan minipig (A, B), and MeLiM (C, D). (B) Transmission photograph correspo... |
PMC2387171_F3_22834.jpg | What is being portrayed in this visual content? | RACK1 expression in normal pig epidermis. (A, C, D) Confocal microscopy analysis of RACK1 protein (green fluorescence), and double labelling for either MITF (A, C) or DCT (D) (red fluorescence) on pig skin. Normal epidermis were from control Meishan minipig (A, B), and MeLiM (C, D). (B) Transmission photograph correspo... |
PMC2387171_F3_22832.jpg | What is the focal point of this photograph? | RACK1 expression in normal pig epidermis. (A, C, D) Confocal microscopy analysis of RACK1 protein (green fluorescence), and double labelling for either MITF (A, C) or DCT (D) (red fluorescence) on pig skin. Normal epidermis were from control Meishan minipig (A, B), and MeLiM (C, D). (B) Transmission photograph correspo... |
PMC2387171_F4_22839.jpg | What is the core subject represented in this visual? | Cellular distribution of RACK1 in MeLiM melanoma at different progression stages. Confocal microscopy analysis of RACK1 (green fluorescence), and double labelling for MITF (red fluorescence). (A) Cutaneous melanoma. (B-D) Melanoma metastasis in a lymph node (B), lung (C) and heart (D). Three dimensional 'orthogonal' sl... |
PMC2387171_F4_22837.jpg | What is the main focus of this visual representation? | Cellular distribution of RACK1 in MeLiM melanoma at different progression stages. Confocal microscopy analysis of RACK1 (green fluorescence), and double labelling for MITF (red fluorescence). (A) Cutaneous melanoma. (B-D) Melanoma metastasis in a lymph node (B), lung (C) and heart (D). Three dimensional 'orthogonal' sl... |
PMC2387171_F4_22840.jpg | What is the principal component of this image? | Cellular distribution of RACK1 in MeLiM melanoma at different progression stages. Confocal microscopy analysis of RACK1 (green fluorescence), and double labelling for MITF (red fluorescence). (A) Cutaneous melanoma. (B-D) Melanoma metastasis in a lymph node (B), lung (C) and heart (D). Three dimensional 'orthogonal' sl... |
PMC2387171_F4_22838.jpg | What is the main focus of this visual representation? | Cellular distribution of RACK1 in MeLiM melanoma at different progression stages. Confocal microscopy analysis of RACK1 (green fluorescence), and double labelling for MITF (red fluorescence). (A) Cutaneous melanoma. (B-D) Melanoma metastasis in a lymph node (B), lung (C) and heart (D). Three dimensional 'orthogonal' sl... |
PMC2387171_F5_22848.jpg | What does this image primarily show? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F5_22850.jpg | What's the most prominent thing you notice in this picture? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F5_22851.jpg | What is being portrayed in this visual content? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F5_22847.jpg | What stands out most in this visual? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F5_22846.jpg | What key item or scene is captured in this photo? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F5_22849.jpg | What's the most prominent thing you notice in this picture? | Cellular distribution of RACK1 in human cutaneous melanocytic proliferations. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence), with MITF (red fluorescence). (A) Control human skin: an MITF-positive melanocyte is localised to the basal membrane. (B-D) Nevi: lentiginous proliferatio... |
PMC2387171_F6_22845.jpg | What object or scene is depicted here? | RACK1 in human melanoma metastasis. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence) and MITF (red fluorescence). (A, B) Melanoma metastasis in lymph node. (C, D) Melanoma metastasis in liver. High levels of RACK1 are seen in the cytoplasm of all metastatic human melanocytes. Secti... |
PMC2387171_F6_22842.jpg | What stands out most in this visual? | RACK1 in human melanoma metastasis. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence) and MITF (red fluorescence). (A, B) Melanoma metastasis in lymph node. (C, D) Melanoma metastasis in liver. High levels of RACK1 are seen in the cytoplasm of all metastatic human melanocytes. Secti... |
PMC2387171_F6_22844.jpg | What's the most prominent thing you notice in this picture? | RACK1 in human melanoma metastasis. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence) and MITF (red fluorescence). (A, B) Melanoma metastasis in lymph node. (C, D) Melanoma metastasis in liver. High levels of RACK1 are seen in the cytoplasm of all metastatic human melanocytes. Secti... |
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