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PMC2387171_F6_22843.jpg
What is shown in this image?
RACK1 in human melanoma metastasis. Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence) and MITF (red fluorescence). (A, B) Melanoma metastasis in lymph node. (C, D) Melanoma metastasis in liver. High levels of RACK1 are seen in the cytoplasm of all metastatic human melanocytes. Secti...
PMC2387171_F7_22852.jpg
Describe the main subject of this image.
Cellular distribution of activated PKC in human nevi and melanoma. (A, B) Confocal microscopy analysis of double labelling of phospho-PKCαβ protein (green fluorescence, biotin amplified signal) and MITF (red fluorescence). (C, D) Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence, bio...
PMC2387171_F7_22855.jpg
What can you see in this picture?
Cellular distribution of activated PKC in human nevi and melanoma. (A, B) Confocal microscopy analysis of double labelling of phospho-PKCαβ protein (green fluorescence, biotin amplified signal) and MITF (red fluorescence). (C, D) Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence, bio...
PMC2387171_F7_22854.jpg
What key item or scene is captured in this photo?
Cellular distribution of activated PKC in human nevi and melanoma. (A, B) Confocal microscopy analysis of double labelling of phospho-PKCαβ protein (green fluorescence, biotin amplified signal) and MITF (red fluorescence). (C, D) Confocal microscopy analysis of double labelling of RACK1 protein (green fluorescence, bio...
PMC2390517_F6_22876.jpg
What is being portrayed in this visual content?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22859.jpg
Describe the main subject of this image.
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22862.jpg
What is the principal component of this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22857.jpg
What's the most prominent thing you notice in this picture?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22861.jpg
What is shown in this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22875.jpg
Describe the main subject of this image.
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22870.jpg
What is the focal point of this photograph?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22874.jpg
What key item or scene is captured in this photo?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22867.jpg
What is the dominant medical problem in this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22868.jpg
What object or scene is depicted here?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22856.jpg
Describe the main subject of this image.
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22869.jpg
Can you identify the primary element in this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22866.jpg
What is the core subject represented in this visual?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22858.jpg
What is the focal point of this photograph?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22860.jpg
What is shown in this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22873.jpg
What is the main focus of this visual representation?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22864.jpg
What is the dominant medical problem in this image?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22863.jpg
What object or scene is depicted here?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F6_22871.jpg
What's the most prominent thing you notice in this picture?
PKD3 expression at embryonic stage E14.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E14.5 mouse embryos. (A) – (C) Control sections incubated without primary antibody. (D) – (U) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, ce: cerebellum, cp: choroid plexus,...
PMC2390517_F7_22886.jpg
What is being portrayed in this visual content?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22891.jpg
What can you see in this picture?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22892.jpg
What stands out most in this visual?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22882.jpg
What is the principal component of this image?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22887.jpg
What's the most prominent thing you notice in this picture?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22883.jpg
What is the central feature of this picture?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22877.jpg
What is the main focus of this visual representation?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22880.jpg
Can you identify the primary element in this image?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22878.jpg
What is being portrayed in this visual content?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22884.jpg
What is the main focus of this visual representation?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22889.jpg
What is the principal component of this image?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22881.jpg
What is being portrayed in this visual content?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22888.jpg
Can you identify the primary element in this image?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22885.jpg
What stands out most in this visual?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22893.jpg
What is the principal component of this image?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390517_F7_22890.jpg
What is the main focus of this visual representation?
PKD3 expression at embryonic stage E16.5. Immunohistochemistry was performed on sagittal sections (6 μm) of E16.5 mouse embryos. (A) – (B) Control sections incubated without primary antibody. (C) – (Q) Sections incubated with anti-PKD3 antibody (1:2000). bl: basal layer of epidermis, cc: costal cartilage, cp: choroid p...
PMC2390526_F1_22894.jpg
What's the most prominent thing you notice in this picture?
Distribution of abdominal fat as measured by FatScan software on a CT scan at the umbilicus level. The visceral fat area was regarded as red, and the subcutaneous fat area was regarded as pink.
PMC2390554_F2_22897.jpg
What can you see in this picture?
Case no. 23 in Group 2. A 78-year-old female patient suffered from prolonged mid-back pain secondary to a fall accident. (A-1,2) Plain radiographs showed L1 osteoporotic compression fracture. (B-1,2) the T2W MR image demonstrated non-healed L1 compression fracture as presenting high signal intensity in intra-vertebral ...
PMC2390554_F2_22895.jpg
What object or scene is depicted here?
Case no. 23 in Group 2. A 78-year-old female patient suffered from prolonged mid-back pain secondary to a fall accident. (A-1,2) Plain radiographs showed L1 osteoporotic compression fracture. (B-1,2) the T2W MR image demonstrated non-healed L1 compression fracture as presenting high signal intensity in intra-vertebral ...
PMC2390554_F2_22898.jpg
Can you identify the primary element in this image?
Case no. 23 in Group 2. A 78-year-old female patient suffered from prolonged mid-back pain secondary to a fall accident. (A-1,2) Plain radiographs showed L1 osteoporotic compression fracture. (B-1,2) the T2W MR image demonstrated non-healed L1 compression fracture as presenting high signal intensity in intra-vertebral ...
PMC2390554_F2_22896.jpg
What does this image primarily show?
Case no. 23 in Group 2. A 78-year-old female patient suffered from prolonged mid-back pain secondary to a fall accident. (A-1,2) Plain radiographs showed L1 osteoporotic compression fracture. (B-1,2) the T2W MR image demonstrated non-healed L1 compression fracture as presenting high signal intensity in intra-vertebral ...
PMC2390555_F3_22901.jpg
What does this image primarily show?
Preoperative plain radiographs showing wide acetabular osteolysis.
PMC2390555_F5_22903.jpg
What key item or scene is captured in this photo?
MRI of the corresponding area.
PMC2390555_F6_22902.jpg
What is the central feature of this picture?
Postoperative plain radiographs.
PMC2390573_F5_22905.jpg
What is shown in this image?
The expression of CD44 and CD24 of histological sections by immunochemistry analysis. (A, B) CD44 and CD24 staining from the xenograft tumors driven by a single sorted cell, respectively. (C, D) CD44 and CD24 staining from the xenograft tumors driven by unsorted TM40D cells, respectively. (both 20 objective).
PMC2390573_F5_22907.jpg
Describe the main subject of this image.
The expression of CD44 and CD24 of histological sections by immunochemistry analysis. (A, B) CD44 and CD24 staining from the xenograft tumors driven by a single sorted cell, respectively. (C, D) CD44 and CD24 staining from the xenograft tumors driven by unsorted TM40D cells, respectively. (both 20 objective).
PMC2390573_F5_22904.jpg
What does this image primarily show?
The expression of CD44 and CD24 of histological sections by immunochemistry analysis. (A, B) CD44 and CD24 staining from the xenograft tumors driven by a single sorted cell, respectively. (C, D) CD44 and CD24 staining from the xenograft tumors driven by unsorted TM40D cells, respectively. (both 20 objective).
PMC2390576_F2_22909.jpg
What is the focal point of this photograph?
Selective digital subtraction arteriography of the right kidney showing an area of tortuous vascular channels located in the lower renal pole. The image taken a few seconds after the injection of contrast material demonstrates also early filling of the renal vein.
PMC2390577_F3_22910.jpg
What is the central feature of this picture?
RVOT morphology and Doppler study of the mitral valve. (A) Short axis image demonstrating the subaortic ventricular septal defect (arrow), hypoplastic right ventricular outflow tract (RVOT), main pulmonary artery (M) with confluent branch pulmonary arteries. L, left pulmonary artery; RA, right atrium; LA, left atrium. ...
PMC2390578_F2_22913.jpg
What stands out most in this visual?
Computed tomography scans demonstrating the destruction of the sternoclavicular joints bilaterally (solid arrow), with a large effusion of the left sternoclavicular joint (hollow arrow). (a) Coronal image; (b) sagittal image.
PMC2390578_F2_22914.jpg
What is the dominant medical problem in this image?
Computed tomography scans demonstrating the destruction of the sternoclavicular joints bilaterally (solid arrow), with a large effusion of the left sternoclavicular joint (hollow arrow). (a) Coronal image; (b) sagittal image.
PMC2390582_F1_22915.jpg
What is being portrayed in this visual content?
Chest CT of a patient with necrotizing pneumonia caused by CA-MRSA USA300 genotype. The CT scan, obtained on hospital day 5, shows multiple nodular lesions, some with a central cavitation, and bilateral pleural effusion.
PMC2390764_ppat-1000085-g001_22917.jpg
What is being portrayed in this visual content?
Analysis of purified influenza virus preparations.(A) Electron micrograph of negatively stained, sucrose gradient purified influenza A/WSN/33 virus at 50,000× magnification. (B) SDS-PAGE separation of proteins in a purified influenza virus preparation. 15 ug of untreated (lane 1) or deglycosylated (lane 2) proteins wer...
PMC2390764_ppat-1000085-g005_22921.jpg
What is the central feature of this picture?
Immunogold labeling of host proteins in purified influenza virions.Influenza virions purified from the supernatant of infected Vero cells were immunogold labeled with antibodies against (A) Hemagglutinin, (B) CD9, (C) CD81 and (D) normal mouse IgG. Labeled virus was negatively stained with sodium silicotungstate and vi...
PMC2390764_ppat-1000085-g005_22918.jpg
What stands out most in this visual?
Immunogold labeling of host proteins in purified influenza virions.Influenza virions purified from the supernatant of infected Vero cells were immunogold labeled with antibodies against (A) Hemagglutinin, (B) CD9, (C) CD81 and (D) normal mouse IgG. Labeled virus was negatively stained with sodium silicotungstate and vi...
PMC2390764_ppat-1000085-g005_22920.jpg
What is the central feature of this picture?
Immunogold labeling of host proteins in purified influenza virions.Influenza virions purified from the supernatant of infected Vero cells were immunogold labeled with antibodies against (A) Hemagglutinin, (B) CD9, (C) CD81 and (D) normal mouse IgG. Labeled virus was negatively stained with sodium silicotungstate and vi...
PMC2390850_pone-0002327-g001_22925.jpg
Can you identify the primary element in this image?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22928.jpg
What can you see in this picture?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22929.jpg
What is the dominant medical problem in this image?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22932.jpg
What is the central feature of this picture?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22923.jpg
What is the focal point of this photograph?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22924.jpg
What's the most prominent thing you notice in this picture?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22922.jpg
What is the principal component of this image?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22934.jpg
What's the most prominent thing you notice in this picture?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22931.jpg
What key item or scene is captured in this photo?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g001_22926.jpg
What is shown in this image?
Phase contrast images of NEB-1 keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. Some loss of adhesion occurs at such high strains, which is why cell strain is slightly negative when the rubber substrate is returned to its relaxed state (M)....
PMC2390850_pone-0002327-g003_22943.jpg
What is being portrayed in this visual content?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22944.jpg
What is the principal component of this image?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22940.jpg
What is the core subject represented in this visual?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22935.jpg
What stands out most in this visual?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22937.jpg
Describe the main subject of this image.
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22946.jpg
What's the most prominent thing you notice in this picture?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22936.jpg
What is the core subject represented in this visual?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22938.jpg
What is shown in this image?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22945.jpg
What's the most prominent thing you notice in this picture?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22941.jpg
What key item or scene is captured in this photo?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390850_pone-0002327-g003_22947.jpg
What key item or scene is captured in this photo?
Fluorescent images of NEB-1 K14-GFP keratinocytes undergoing incremental uniaxial strain.Average uniaxial strain is reported in the lower left corner of each panel. These images demonstrate that the cytokeratin network is remarkably robust and can withstand dramatic uniaxial strains without rupturing. In some cases, ke...
PMC2390852_pone-0002334-g007_22956.jpg
Can you identify the primary element in this image?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2390852_pone-0002334-g007_22952.jpg
What is the main focus of this visual representation?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2390852_pone-0002334-g007_22955.jpg
What is the central feature of this picture?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2390852_pone-0002334-g007_22948.jpg
What does this image primarily show?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2390852_pone-0002334-g007_22951.jpg
What is the dominant medical problem in this image?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2390852_pone-0002334-g007_22949.jpg
What is the central feature of this picture?
VAPP58S impairs BMP signalling at the synapse.A–C, representative confocal images of the synapse at muscle 6–7 stained with phosphorylated SMAD (pMAD; red) and bruchpilot (nc82, green), a component of the active zone. (A) In control animals (G14-GAL4/+) postsynaptic expression of pMAD coincides with the expression of p...
PMC2391082_f4_22968.jpg
What is the focal point of this photograph?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22964.jpg
What stands out most in this visual?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22967.jpg
Describe the main subject of this image.
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22966.jpg
What stands out most in this visual?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22963.jpg
What key item or scene is captured in this photo?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22965.jpg
What's the most prominent thing you notice in this picture?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f4_22962.jpg
What is the dominant medical problem in this image?
Transverse sections of specimens demonstrating severe eye defects following Psf2MO-mediated knockdown. Dorsal is toward the top in each figure. A: Image montage of a typical specimen shows the Psf2 morpholino-injected side on the left and the internal control, uninjected side on the right. This image was viewed with di...
PMC2391082_f5_22960.jpg
What stands out most in this visual?
Diagrams illustrating the tissue transplantation experiment performed to localize Psf2 function in the eye. This experiment involves reciprocal transplantation of stage 14 presumptive lens ectoderm (ple) between uninjected embryos (upper example) and morpholino (MO)-injected embryos (lower example). Single blastomeres ...
PMC2391082_f5_22959.jpg
What is the focal point of this photograph?
Diagrams illustrating the tissue transplantation experiment performed to localize Psf2 function in the eye. This experiment involves reciprocal transplantation of stage 14 presumptive lens ectoderm (ple) between uninjected embryos (upper example) and morpholino (MO)-injected embryos (lower example). Single blastomeres ...
PMC2391082_f5_22957.jpg
What object or scene is depicted here?
Diagrams illustrating the tissue transplantation experiment performed to localize Psf2 function in the eye. This experiment involves reciprocal transplantation of stage 14 presumptive lens ectoderm (ple) between uninjected embryos (upper example) and morpholino (MO)-injected embryos (lower example). Single blastomeres ...
PMC2391084_f3_22978.jpg
What is the main focus of this visual representation?
Enhanced green fluorescent protein expression during retinal development in Tg(ccnb1:EGFP)nt18 zebrafish. Enhanced green fluorescent protein (EGFP; A-D), proliferating cell nuclear antigen (PCNA; E-H), and merged expression patterns (I-L) are shown at 36, 48, 72 hpf, and 5 dpf of retinal development. At 36 hpf, PCNA an...
PMC2391084_f3_22971.jpg
What does this image primarily show?
Enhanced green fluorescent protein expression during retinal development in Tg(ccnb1:EGFP)nt18 zebrafish. Enhanced green fluorescent protein (EGFP; A-D), proliferating cell nuclear antigen (PCNA; E-H), and merged expression patterns (I-L) are shown at 36, 48, 72 hpf, and 5 dpf of retinal development. At 36 hpf, PCNA an...
PMC2391084_f3_22972.jpg
What stands out most in this visual?
Enhanced green fluorescent protein expression during retinal development in Tg(ccnb1:EGFP)nt18 zebrafish. Enhanced green fluorescent protein (EGFP; A-D), proliferating cell nuclear antigen (PCNA; E-H), and merged expression patterns (I-L) are shown at 36, 48, 72 hpf, and 5 dpf of retinal development. At 36 hpf, PCNA an...
PMC2391084_f3_22977.jpg
What is the focal point of this photograph?
Enhanced green fluorescent protein expression during retinal development in Tg(ccnb1:EGFP)nt18 zebrafish. Enhanced green fluorescent protein (EGFP; A-D), proliferating cell nuclear antigen (PCNA; E-H), and merged expression patterns (I-L) are shown at 36, 48, 72 hpf, and 5 dpf of retinal development. At 36 hpf, PCNA an...