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PMC1906762_F7_11962.jpg
What's the most prominent thing you notice in this picture?
Differentiation can be uncoupled from delamination. (A-H). Confocal sections of chicken embryonic pancreata 52 hours after electroporation with Ngn3 (A-B), Ngn3 and Notch1ICD (C-D), NeuroD (E-F), or NeuroD and Notch1ICD (G-H) subjected to immunohistochemical stainings against Pax6 (red) and laminin (blue) (A, C, E, G) ...
PMC1906762_F7_11967.jpg
What key item or scene is captured in this photo?
Differentiation can be uncoupled from delamination. (A-H). Confocal sections of chicken embryonic pancreata 52 hours after electroporation with Ngn3 (A-B), Ngn3 and Notch1ICD (C-D), NeuroD (E-F), or NeuroD and Notch1ICD (G-H) subjected to immunohistochemical stainings against Pax6 (red) and laminin (blue) (A, C, E, G) ...
PMC1906762_F8_11971.jpg
What is the main focus of this visual representation?
Myt1 can partially rescue the inhibitory effect by Notch1ICD on Ngn3 function. (A-K). Immunohistochemical stainings (A, E, I-K) and in situ hybridizations (B-D, F-H) on sections in the duodenum 52 hours after electroporation with Ngn3 (A-D, I), Ngn3 and Notch1ICD (E-H, J) or Ngn3 with Notch1ICD and MyT1 (K) showing exp...
PMC1906762_F8_11972.jpg
What is the main focus of this visual representation?
Myt1 can partially rescue the inhibitory effect by Notch1ICD on Ngn3 function. (A-K). Immunohistochemical stainings (A, E, I-K) and in situ hybridizations (B-D, F-H) on sections in the duodenum 52 hours after electroporation with Ngn3 (A-D, I), Ngn3 and Notch1ICD (E-H, J) or Ngn3 with Notch1ICD and MyT1 (K) showing exp...
PMC1906762_F8_11976.jpg
What is the core subject represented in this visual?
Myt1 can partially rescue the inhibitory effect by Notch1ICD on Ngn3 function. (A-K). Immunohistochemical stainings (A, E, I-K) and in situ hybridizations (B-D, F-H) on sections in the duodenum 52 hours after electroporation with Ngn3 (A-D, I), Ngn3 and Notch1ICD (E-H, J) or Ngn3 with Notch1ICD and MyT1 (K) showing exp...
PMC1906762_F8_11975.jpg
What does this image primarily show?
Myt1 can partially rescue the inhibitory effect by Notch1ICD on Ngn3 function. (A-K). Immunohistochemical stainings (A, E, I-K) and in situ hybridizations (B-D, F-H) on sections in the duodenum 52 hours after electroporation with Ngn3 (A-D, I), Ngn3 and Notch1ICD (E-H, J) or Ngn3 with Notch1ICD and MyT1 (K) showing exp...
PMC1906762_F8_11973.jpg
What object or scene is depicted here?
Myt1 can partially rescue the inhibitory effect by Notch1ICD on Ngn3 function. (A-K). Immunohistochemical stainings (A, E, I-K) and in situ hybridizations (B-D, F-H) on sections in the duodenum 52 hours after electroporation with Ngn3 (A-D, I), Ngn3 and Notch1ICD (E-H, J) or Ngn3 with Notch1ICD and MyT1 (K) showing exp...
PMC1906777_F1_11982.jpg
What does this image primarily show?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11988.jpg
What is shown in this image?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11985.jpg
What can you see in this picture?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11980.jpg
Can you identify the primary element in this image?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11987.jpg
Describe the main subject of this image.
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11986.jpg
What is shown in this image?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11981.jpg
What stands out most in this visual?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11989.jpg
What can you see in this picture?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11984.jpg
What can you see in this picture?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11983.jpg
Can you identify the primary element in this image?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906777_F1_11990.jpg
What is the focal point of this photograph?
Transgene expression in rat hippocampus, 3 weeks post-infusion. A group of test animals (n = 3 per group) was injected with AAV1 vectors and brains analysed for transgene expression (anti-amyloid beta protein, Chemicon, MAB1560, 6E10, specific for human Aβ). No Aβ expression was observed in naïve rat brain. Infusion of...
PMC1906782_F3_11997.jpg
Describe the main subject of this image.
Ovules and leaves were stained with DiOC. Panel A. The wild type ST4793R was used unless otherwise noted. Water stained controls showed no auto fluorescence (data not shown). The fiberless mutant SL1-7-1 was used where indicated. The magnification is indicated in parentheses under the picture. Panel B. An image of a 20...
PMC1906782_F3_11994.jpg
What does this image primarily show?
Ovules and leaves were stained with DiOC. Panel A. The wild type ST4793R was used unless otherwise noted. Water stained controls showed no auto fluorescence (data not shown). The fiberless mutant SL1-7-1 was used where indicated. The magnification is indicated in parentheses under the picture. Panel B. An image of a 20...
PMC1906782_F3_11995.jpg
What's the most prominent thing you notice in this picture?
Ovules and leaves were stained with DiOC. Panel A. The wild type ST4793R was used unless otherwise noted. Water stained controls showed no auto fluorescence (data not shown). The fiberless mutant SL1-7-1 was used where indicated. The magnification is indicated in parentheses under the picture. Panel B. An image of a 20...
PMC1906783_F6_11999.jpg
Can you identify the primary element in this image?
Microscopic analysis of roots from T2 homozygous transgenic plants (p BjMTP1::mRFP1 and GUSPlus) after exposure to 50 μM Ni2+ for 48 h. Images of cross sections taken from the top of the main root under bright field illumination, using diascopic filters at 10× (A) and 20× (B) magnification, and fluorescent images of th...
PMC1906783_F6_12000.jpg
What is the principal component of this image?
Microscopic analysis of roots from T2 homozygous transgenic plants (p BjMTP1::mRFP1 and GUSPlus) after exposure to 50 μM Ni2+ for 48 h. Images of cross sections taken from the top of the main root under bright field illumination, using diascopic filters at 10× (A) and 20× (B) magnification, and fluorescent images of th...
PMC1906783_F6_12004.jpg
What stands out most in this visual?
Microscopic analysis of roots from T2 homozygous transgenic plants (p BjMTP1::mRFP1 and GUSPlus) after exposure to 50 μM Ni2+ for 48 h. Images of cross sections taken from the top of the main root under bright field illumination, using diascopic filters at 10× (A) and 20× (B) magnification, and fluorescent images of th...
PMC1906783_F6_12002.jpg
What is the core subject represented in this visual?
Microscopic analysis of roots from T2 homozygous transgenic plants (p BjMTP1::mRFP1 and GUSPlus) after exposure to 50 μM Ni2+ for 48 h. Images of cross sections taken from the top of the main root under bright field illumination, using diascopic filters at 10× (A) and 20× (B) magnification, and fluorescent images of th...
PMC1906783_F6_12001.jpg
What is the dominant medical problem in this image?
Microscopic analysis of roots from T2 homozygous transgenic plants (p BjMTP1::mRFP1 and GUSPlus) after exposure to 50 μM Ni2+ for 48 h. Images of cross sections taken from the top of the main root under bright field illumination, using diascopic filters at 10× (A) and 20× (B) magnification, and fluorescent images of th...
PMC1906796_F1_12005.jpg
What is the main focus of this visual representation?
Representations of meniscal extrusion as seen using magnetic resonance imaging. Human knee medial compartment: (a) and (b) sagittal views, and (c) reconstructed coronal view. Partial and total meniscal extrusion at the anterior horn are shown in panels a and b, respectively. Panel c shows a partial (> 50%) meniscal ext...
PMC1906796_F1_12006.jpg
What is the dominant medical problem in this image?
Representations of meniscal extrusion as seen using magnetic resonance imaging. Human knee medial compartment: (a) and (b) sagittal views, and (c) reconstructed coronal view. Partial and total meniscal extrusion at the anterior horn are shown in panels a and b, respectively. Panel c shows a partial (> 50%) meniscal ext...
PMC1906796_F1_12007.jpg
What's the most prominent thing you notice in this picture?
Representations of meniscal extrusion as seen using magnetic resonance imaging. Human knee medial compartment: (a) and (b) sagittal views, and (c) reconstructed coronal view. Partial and total meniscal extrusion at the anterior horn are shown in panels a and b, respectively. Panel c shows a partial (> 50%) meniscal ext...
PMC1906819_F1_12010.jpg
What is the main focus of this visual representation?
Arthroscopic and magnetic resonance imaging evaluation of cartilage defects treated with autologous chondrocyte grafts (BioSeed®-C). (a) Intra-operative situation of a cartilage defect situated at the femoral condyle covered with transosseously fixed BioSeed-C (20 mm × 30 mm). Note that the healthy cartilage rim is par...
PMC1906819_F1_12011.jpg
What is being portrayed in this visual content?
Arthroscopic and magnetic resonance imaging evaluation of cartilage defects treated with autologous chondrocyte grafts (BioSeed®-C). (a) Intra-operative situation of a cartilage defect situated at the femoral condyle covered with transosseously fixed BioSeed-C (20 mm × 30 mm). Note that the healthy cartilage rim is par...
PMC1906819_F1_12009.jpg
What stands out most in this visual?
Arthroscopic and magnetic resonance imaging evaluation of cartilage defects treated with autologous chondrocyte grafts (BioSeed®-C). (a) Intra-operative situation of a cartilage defect situated at the femoral condyle covered with transosseously fixed BioSeed-C (20 mm × 30 mm). Note that the healthy cartilage rim is par...
PMC1906824_F1_12012.jpg
What is the focal point of this photograph?
Fetal Magnetic Resonance Imaging (MRI) imaging: T2-weighted sequences. Axial Half Fourier Rapid Acquisition with Relaxation Enhancement (RARE) T2-weighted images shows dilation of the middle third of the ureter and coexist homolateral upstream hydronephrosis.
PMC1906824_F2_12015.jpg
What stands out most in this visual?
Magnetic Resonance Imaging (MRI) coronal T2-weighted images (Panel A), coronal MR urography (Panel B), and intrasurgical retrograde ureteropyelogram (Panel C). On coronal T2-weighted images and coronal MRI urography, can be depicted an obstruction of the middle third of the ureter, with upstream hydro-urethronephrosis,...
PMC1906824_F2_12014.jpg
What is the principal component of this image?
Magnetic Resonance Imaging (MRI) coronal T2-weighted images (Panel A), coronal MR urography (Panel B), and intrasurgical retrograde ureteropyelogram (Panel C). On coronal T2-weighted images and coronal MRI urography, can be depicted an obstruction of the middle third of the ureter, with upstream hydro-urethronephrosis,...
PMC1906824_F2_12013.jpg
What is the main focus of this visual representation?
Magnetic Resonance Imaging (MRI) coronal T2-weighted images (Panel A), coronal MR urography (Panel B), and intrasurgical retrograde ureteropyelogram (Panel C). On coronal T2-weighted images and coronal MRI urography, can be depicted an obstruction of the middle third of the ureter, with upstream hydro-urethronephrosis,...
PMC1906865_F1_12016.jpg
What object or scene is depicted here?
Computed tomography (CT) scan of the pelvic area showing a 10 cm × 9.5 cm mass in the cul-de-sac containing heterogenous echogenicities consisting of fat, fluid, soft tissue, and calcifications.
PMC1906870_F1_12019.jpg
What is the focal point of this photograph?
Histological verification of an injection site produced by microinjected synthetic PACAP. (a) Section from control brain, injected with aCSF vehicle. (b) Injected synthetic PACAP (50 pmol) immunoreactivity in the CeA. BLA = basolateral nucleus of the amygdala, CeM = central nucleus of the amygdala medial part, CeL = ce...
PMC1910594_F3_12028.jpg
What is the main focus of this visual representation?
Patients 1. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F3_12026.jpg
What is being portrayed in this visual content?
Patients 1. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F3_12025.jpg
What is the central feature of this picture?
Patients 1. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F3_12027.jpg
What key item or scene is captured in this photo?
Patients 1. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F4_12037.jpg
What is the central feature of this picture?
Patients 2. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F4_12036.jpg
What is the main focus of this visual representation?
Patients 2. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F4_12035.jpg
Describe the main subject of this image.
Patients 2. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F5_12021.jpg
What is the focal point of this photograph?
Patients 3. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F5_12022.jpg
What key item or scene is captured in this photo?
Patients 3. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F5_12024.jpg
What is shown in this image?
Patients 3. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F7_12033.jpg
What is the principal component of this image?
Patients 5. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F7_12029.jpg
What is the dominant medical problem in this image?
Patients 5. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F7_12030.jpg
What can you see in this picture?
Patients 5. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F7_12031.jpg
What key item or scene is captured in this photo?
Patients 5. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910594_F7_12032.jpg
What is the core subject represented in this visual?
Patients 5. A: TTDE before adenosine. B: TTDE after adenosine. C: DW recording. D: coronary angiography with site of DW recording (arrow). DW: Doppler-wire. TTDE: transthoracic Doppler echocardiography.
PMC1910595_F1_12061.jpg
What is the core subject represented in this visual?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12057.jpg
What's the most prominent thing you notice in this picture?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12060.jpg
What is the main focus of this visual representation?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12052.jpg
What key item or scene is captured in this photo?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12055.jpg
What is the main focus of this visual representation?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12054.jpg
What is the focal point of this photograph?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12056.jpg
What is the main focus of this visual representation?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12053.jpg
What is the principal component of this image?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12062.jpg
What can you see in this picture?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12059.jpg
Can you identify the primary element in this image?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12051.jpg
What is the main focus of this visual representation?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12058.jpg
Describe the main subject of this image.
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910595_F1_12050.jpg
What is being portrayed in this visual content?
Microphotographs from Case 3 (a through d) to illustrate basic pattern of inflammatory reaction common to all three adenomas in this report: i.e., angiocentric infiltrates of T lymphocytes (b); colonization of tumor interstitium by arborized cells immunoreactive for S-100 protein (c) and HLA-DR (d), the respective stai...
PMC1910597_F1_12040.jpg
What does this image primarily show?
Ultrasound images of intrahepatic hyperechoic foci in patients with the LPAC syndrome. In these patients, a careful US examination detected intrahepatic hyperechoic foci with diffuse topography compatible with lipid deposits along the luminal surface of the intrahepatic biliary tree (Arrows). These multiple dots, less ...
PMC1910599_F1_12039.jpg
What is the focal point of this photograph?
Craniocaudad mammographic views showing generalized increased radioopacity within the left breast.
PMC1910599_F3_12041.jpg
Can you identify the primary element in this image?
Mediolateral oblique mammographic views showing increased radioopacity within the upper pole of the left breast.
PMC1910601_F1_12044.jpg
What is the focal point of this photograph?
MRI showing (A) cervico-thoracic involvement and (B) thoraco-lumbar involvement. T2 weighted image highlighting heterogenous involvement of the entire spine with preserved disk space and absence of fractures.
PMC1910601_F1_12045.jpg
What's the most prominent thing you notice in this picture?
MRI showing (A) cervico-thoracic involvement and (B) thoraco-lumbar involvement. T2 weighted image highlighting heterogenous involvement of the entire spine with preserved disk space and absence of fractures.
PMC1910602_F1_12047.jpg
What object or scene is depicted here?
Imaging of the abdomen (coronal view). Left: CT scan showing tumours of the ascending colon, seen at the hepatic flexure (red arrow), and of the transverse colon (white arrow), seen in the left inguinoscrotal hernia sac. Right: Diagrammatic representation of the tumour sites.
PMC1910602_F2_12046.jpg
What key item or scene is captured in this photo?
Imaging of the abdomen (cross sectional). CT scan showing tumour of the transverse colon (white arrow) presenting within a left inguinoscrotal hernia.
PMC1910610_pone-0000615-g007_12065.jpg
What is the dominant medical problem in this image?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12073.jpg
What key item or scene is captured in this photo?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12080.jpg
What is the principal component of this image?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12068.jpg
What's the most prominent thing you notice in this picture?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12072.jpg
What key item or scene is captured in this photo?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12064.jpg
What can you see in this picture?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12076.jpg
What can you see in this picture?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12067.jpg
What is the central feature of this picture?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12075.jpg
What does this image primarily show?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g007_12071.jpg
What is the central feature of this picture?
Unscheduled Activation of PERK Restricts Acinar Growth and Promotes Apoptosis in 3D Matrigel.(A) Time-dependent increase in phosphorylation of eIF2α in MCF10A cells expressing an Fv2E-ΔNPERK construct, upon treatment with the dimerizing drug, AP20187 (2 nM). AP20187 has no effect on P-eIF2α levels in β-Gal cells. Total...
PMC1910610_pone-0000615-g009_12091.jpg
What is the dominant medical problem in this image?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12090.jpg
Describe the main subject of this image.
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12089.jpg
Can you identify the primary element in this image?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12083.jpg
What object or scene is depicted here?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12082.jpg
What is the principal component of this image?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12088.jpg
What is the core subject represented in this visual?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12084.jpg
What is being portrayed in this visual content?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g009_12085.jpg
What is the core subject represented in this visual?
PERK Inhibition Results in Increased Laminin-5 Production, Secretion and Deposition.(A) Confocal images showing the equatorial cross sections through β-Gal (A-a, A-b and A-f) and PERKΔC (A-c to A-e and A-g to A-i) acini stained for Laminin-5 (green), on Day 8 in 3D. Note the increased staining and disorganized Laminin-...
PMC1910610_pone-0000615-g010_12096.jpg
What is shown in this image?
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1910610_pone-0000615-g010_12092.jpg
What is being portrayed in this visual content?
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1910610_pone-0000615-g010_12101.jpg
Describe the main subject of this image.
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1910610_pone-0000615-g010_12095.jpg
What is the principal component of this image?
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1910610_pone-0000615-g010_12099.jpg
Can you identify the primary element in this image?
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1910610_pone-0000615-g010_12098.jpg
What is the principal component of this image?
PERK Inhibition in MCF10A Cells Favors Mammary Tumor Formation.(A) Western blot for ErbB1 (EGFR) and ErbB2 (Her2) levels in adhered β-Gal or PERKΔC cells show increased levels when PERK is inhibited. GAPDH was used as loading control. (B) β-Gal or PERKΔC cells were injected orthotopically into the contralateral abdomin...
PMC1913094_pmed-0040198.g001_12104.jpg
What is the central feature of this picture?
Clinical Appearance of Acute Graft-Versus-Host Disease Involving the Skin and the Upper Intestinal MucosaLeft panel: The diffuse erythematous maculopapular rash typical of acute GVHD. Right panel: an endoscopic view of the edematous, reddened, friable gastrointestinal mucosa seen in a patient with acute GVHD.
PMC1913094_pmed-0040198.g001_12103.jpg
What is shown in this image?
Clinical Appearance of Acute Graft-Versus-Host Disease Involving the Skin and the Upper Intestinal MucosaLeft panel: The diffuse erythematous maculopapular rash typical of acute GVHD. Right panel: an endoscopic view of the edematous, reddened, friable gastrointestinal mucosa seen in a patient with acute GVHD.
PMC1913206_pone-0000618-g002_12128.jpg
Can you identify the primary element in this image?
FRAP reveals distinct anucleate cells in the cdc16-116 mutant.(a) Merged pseudo-colors image of cdc16-116 cells expressing Rad24p-GFP (green) stained with the cell wall tracer aniline blue (red). Temperature sensitive cdc16-116 cells were treated with hydroxyurea (HU) for 6 h to arrest cells at S phase, and shifted to ...