image
stringlengths
20
66
question
stringclasses
16 values
answer
stringlengths
3
10.7k
PMC1919353_F1_12245.jpg
Describe the main subject of this image.
Testicular tumor. A, Sectioned surface of testicular tumor shows an expansile hemorrhagic nodule displacing surrounding testicular tissue (gross). B, Angiosarcoma with classic architectural pattern composed of proliferation of anastomosing blood-filled channels, and focal solid pattern (hematoxylin-eosin, original magn...
PMC1919353_F2_12249.jpg
What can you see in this picture?
Testicular tumor. A, Immunoperoxidase staining for CD34 demonstrates strong positive reactivity in malignant endothelial cells lining the vascular channels (immunoperoxidase, original magnification ×200). B, Immunoperoxidase staining for CD31 demonstrates strong positive reactivity in malignant endothelial cells lining...
PMC1919353_F2_12248.jpg
What object or scene is depicted here?
Testicular tumor. A, Immunoperoxidase staining for CD34 demonstrates strong positive reactivity in malignant endothelial cells lining the vascular channels (immunoperoxidase, original magnification ×200). B, Immunoperoxidase staining for CD31 demonstrates strong positive reactivity in malignant endothelial cells lining...
PMC1919354_F1_12243.jpg
Can you identify the primary element in this image?
Photomicrography of the kidney shows dilated premature cysts, immature mesenchyme and glomerulus (H&E ×20). Inset showing primitive glomerulus with cuboidal lining epithelium of Bowman's capsule and cartilaginous focus (H&E ×400).
PMC1919354_F1_12241.jpg
What is the focal point of this photograph?
Photomicrography of the kidney shows dilated premature cysts, immature mesenchyme and glomerulus (H&E ×20). Inset showing primitive glomerulus with cuboidal lining epithelium of Bowman's capsule and cartilaginous focus (H&E ×400).
PMC1919354_F1_12242.jpg
What's the most prominent thing you notice in this picture?
Photomicrography of the kidney shows dilated premature cysts, immature mesenchyme and glomerulus (H&E ×20). Inset showing primitive glomerulus with cuboidal lining epithelium of Bowman's capsule and cartilaginous focus (H&E ×400).
PMC1920549_pone-0000633-g006_12256.jpg
What stands out most in this visual?
Preferential extension of the TC-substrate contact side that is the closest to the GA.(A-C) Time sequence of top views of three-dimensional images of fluorescently labeled GA (arrow in B) in a TC sitting on the TCR-binding substrate. Scale bar, 10 µm. Time interval, 1 min. (D-F) Transmitted-light images of the same cel...
PMC1920549_pone-0000633-g006_12255.jpg
What key item or scene is captured in this photo?
Preferential extension of the TC-substrate contact side that is the closest to the GA.(A-C) Time sequence of top views of three-dimensional images of fluorescently labeled GA (arrow in B) in a TC sitting on the TCR-binding substrate. Scale bar, 10 µm. Time interval, 1 min. (D-F) Transmitted-light images of the same cel...
PMC1920549_pone-0000633-g006_12258.jpg
What is the main focus of this visual representation?
Preferential extension of the TC-substrate contact side that is the closest to the GA.(A-C) Time sequence of top views of three-dimensional images of fluorescently labeled GA (arrow in B) in a TC sitting on the TCR-binding substrate. Scale bar, 10 µm. Time interval, 1 min. (D-F) Transmitted-light images of the same cel...
PMC1920549_pone-0000633-g006_12252.jpg
What stands out most in this visual?
Preferential extension of the TC-substrate contact side that is the closest to the GA.(A-C) Time sequence of top views of three-dimensional images of fluorescently labeled GA (arrow in B) in a TC sitting on the TCR-binding substrate. Scale bar, 10 µm. Time interval, 1 min. (D-F) Transmitted-light images of the same cel...
PMC1920555_pone-0000648-g003_12267.jpg
What is the dominant medical problem in this image?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920555_pone-0000648-g003_12262.jpg
What is the central feature of this picture?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920555_pone-0000648-g003_12265.jpg
What stands out most in this visual?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920555_pone-0000648-g003_12264.jpg
What is the dominant medical problem in this image?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920555_pone-0000648-g003_12266.jpg
Can you identify the primary element in this image?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920555_pone-0000648-g003_12263.jpg
What is the core subject represented in this visual?
Examples of standardized seedling morphological phenotypes for quantitative assessment.(a) no scored phenotype; (b) extra leaf, concave cotyledons, aerial organs on growth medium; (c) missing leaf; (d) narrow leaves, delayed development; (e) shoot meristemless, delayed development; (f) necrotic spots on leaves; (g) pur...
PMC1920558_pone-0000652-g007_12273.jpg
What is the principal component of this image?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.
PMC1920558_pone-0000652-g007_12272.jpg
What can you see in this picture?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.
PMC1920558_pone-0000652-g007_12270.jpg
What key item or scene is captured in this photo?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.
PMC1920558_pone-0000652-g007_12271.jpg
What is the principal component of this image?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.
PMC1920558_pone-0000652-g007_12274.jpg
Can you identify the primary element in this image?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained T40/IDE total digest showing spherical (A) annular (B, I–II) and beaded (C, III) protofibrils. The bar represents 10 nm.
PMC1920592_F1_12275.jpg
What stands out most in this visual?
Round region of heterogeneously increased density in anterior abdominal wall just superior to symphysis pubis. This region measures approximately 3 cm in diameter. Postoperative inflammatory changes are noted just inferior to this region.
PMC1924508_F7_12284.jpg
Can you identify the primary element in this image?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12289.jpg
What object or scene is depicted here?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12288.jpg
What can you see in this picture?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12285.jpg
What key item or scene is captured in this photo?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12286.jpg
What is shown in this image?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12290.jpg
Describe the main subject of this image.
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F7_12283.jpg
What is being portrayed in this visual content?
Fluorescence micrographs showing representative NuMA staining patterns in individual nuclei for eight different phenotypes. In previous work [5] the radial nuclear distribution of NuMA was analyzed from 3D multichannel fluorescence images of thousands of individual nuclei. The human mammary epithelial cells were either...
PMC1924508_F8_12279.jpg
What key item or scene is captured in this photo?
LBF analysis of the distribution of NuMA from 3D images. (a) Fluorescence micrograph of Texas red-immunolabeled NuMA from a single optical section, in differentiated non-neoplastic S1 cells. (b) The corresponding processed image section showing a composite view of the detected local bright features (light gray) of NuMA...
PMC1924508_F8_12282.jpg
What is the dominant medical problem in this image?
LBF analysis of the distribution of NuMA from 3D images. (a) Fluorescence micrograph of Texas red-immunolabeled NuMA from a single optical section, in differentiated non-neoplastic S1 cells. (b) The corresponding processed image section showing a composite view of the detected local bright features (light gray) of NuMA...
PMC1924509_F1_12276.jpg
What is the core subject represented in this visual?
Consecutive time-lapse images of MTs taken at 4 sec. intervals. Examples of growing (G) and shortening (S) MTs are marked. Tip locations of these MTs are manually tracked over time by marking on consecutive frames to calculate the growth and shortening statistics.
PMC1924509_F1_12278.jpg
Can you identify the primary element in this image?
Consecutive time-lapse images of MTs taken at 4 sec. intervals. Examples of growing (G) and shortening (S) MTs are marked. Tip locations of these MTs are manually tracked over time by marking on consecutive frames to calculate the growth and shortening statistics.
PMC1924514_F1_12292.jpg
What is being portrayed in this visual content?
The result of applying 3D median filtering using a kernel size of 5 × 5 × 5 pixels. (A) Shows the original data, of size 234 × 256 pixels, where each pixel is 27 nm. (B) Shows the median filtered data. The filtering eliminates the fine structure in the image, which can be considered noise for the purpose of contour ext...
PMC1924514_F9_12293.jpg
What is the dominant medical problem in this image?
The 3D torus architecture of the IBM Blue Gene/L machine. There are dedicated interconnections between nearest neighbors on a 3D toroidal grid. This minimizes communication overhead between nearest neighbors, and is an ideal solution for 3D image processing tasks.
PMC1924602_pone-0000657-g003_12296.jpg
What is shown in this image?
Renal interstitial cells located between tubuli or at the border of glomeruli express cadherin-9.Cadherin-9-positive cells were identified by immunohistochemical staining with the affinity-purified anti-cadherin-9 polyclonal antibody. The sections were counterstained with hematoxylin-eosin. Arrows point to some of the ...
PMC1924602_pone-0000657-g003_12295.jpg
What is the dominant medical problem in this image?
Renal interstitial cells located between tubuli or at the border of glomeruli express cadherin-9.Cadherin-9-positive cells were identified by immunohistochemical staining with the affinity-purified anti-cadherin-9 polyclonal antibody. The sections were counterstained with hematoxylin-eosin. Arrows point to some of the ...
PMC1924602_pone-0000657-g008_12297.jpg
Describe the main subject of this image.
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12298.jpg
What's the most prominent thing you notice in this picture?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12300.jpg
What is the central feature of this picture?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12303.jpg
What is the dominant medical problem in this image?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12301.jpg
What is the focal point of this photograph?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12302.jpg
What is being portrayed in this visual content?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924602_pone-0000657-g008_12299.jpg
What is the main focus of this visual representation?
Cadherin-9 is a marker for renal fibroblasts.(A) Immunohistochemical staining of two consecutive kidney cryostat sections with antisera against cadherin-9 and FSP1, a well-known renal fibroblast marker, showed that cadherin-9 positive cells also express FSP1. Staining of FSP1, however, could be also observed in the cad...
PMC1924855_F6_12311.jpg
What does this image primarily show?
Electroporation of SHP-2 shRNA construct into soleus muscle of adult mice leads to disassembly of NMJs. Adult mice soleus muscles were electroporated in vivo with a mixture of pSUPER.shSHP2 and NLS-GFP constructs (A, C), or pSUPER vector and NLS-GFP as control (B, D). After six weeks muscles were dissected, whole mount...
PMC1924855_F6_12310.jpg
What is shown in this image?
Electroporation of SHP-2 shRNA construct into soleus muscle of adult mice leads to disassembly of NMJs. Adult mice soleus muscles were electroporated in vivo with a mixture of pSUPER.shSHP2 and NLS-GFP constructs (A, C), or pSUPER vector and NLS-GFP as control (B, D). After six weeks muscles were dissected, whole mount...
PMC1924856_F1_12305.jpg
What is the core subject represented in this visual?
a. Cytology consistent with papillary thyroid cancer including nuclear size variation, microfollicle cellular arrangement and an intranuclear pseudo-inclusion (arrow). Papanicolaou stain at 400× magnification. b. Final histology showed a papillary carcinoma, follicular variant. There are characteristic nuclear features...
PMC1924856_F1_12304.jpg
What does this image primarily show?
a. Cytology consistent with papillary thyroid cancer including nuclear size variation, microfollicle cellular arrangement and an intranuclear pseudo-inclusion (arrow). Papanicolaou stain at 400× magnification. b. Final histology showed a papillary carcinoma, follicular variant. There are characteristic nuclear features...
PMC1924856_F2_12306.jpg
What is the main focus of this visual representation?
CT scan of the chest that cuts from the apices (1) to the lung bases (4) and shows tremendous tumor burden as well as a basilar prominence of metastases typical of papillary thyroid carcinoma lung metastases.
PMC1924856_F2_12309.jpg
What is being portrayed in this visual content?
CT scan of the chest that cuts from the apices (1) to the lung bases (4) and shows tremendous tumor burden as well as a basilar prominence of metastases typical of papillary thyroid carcinoma lung metastases.
PMC1924856_F2_12308.jpg
What is the central feature of this picture?
CT scan of the chest that cuts from the apices (1) to the lung bases (4) and shows tremendous tumor burden as well as a basilar prominence of metastases typical of papillary thyroid carcinoma lung metastases.
PMC1924869_ppat-0030099-g006_12316.jpg
Can you identify the primary element in this image?
Phagocytosis of iRBCs under Flow(A) Differential interference contrast image of RAW macrophages in a 50-μm channel after lysis of attached RBCs. Arrows show the malarial pigment, hemozoin.(B) Fluorescence image of parasite nuclei ingested by macrophages.(C) DiIC staining of RBC membranes.(D) Parasite DNA fluorescence (...
PMC1924869_ppat-0030099-g006_12315.jpg
What is being portrayed in this visual content?
Phagocytosis of iRBCs under Flow(A) Differential interference contrast image of RAW macrophages in a 50-μm channel after lysis of attached RBCs. Arrows show the malarial pigment, hemozoin.(B) Fluorescence image of parasite nuclei ingested by macrophages.(C) DiIC staining of RBC membranes.(D) Parasite DNA fluorescence (...
PMC1924875_pcbi-0030140-g006_12317.jpg
What is the core subject represented in this visual?
NORSnet Captured Unstructured Regions Related to High Net Charge/Low HydrophobicityDFF45 (white, yellow, and red) becomes structured upon complex formation with DFF40 (purple; [55]). The interface includes a buried hydrophobic patch surrounded by hydrophilic interactions. Usually, charged residues disrupt the formation...
PMC1925057_F1_12323.jpg
Can you identify the primary element in this image?
Case 1 A 41-year-old man presented with upper gastrointestinal bleed. Endoscopy revealed blood coming out from ampulla Fig 1a Axial section of Dual phase CT scan shows hyperdensity (white arrow) within the gallbladder 1b Flush aortogram shows origin of the right hepatic artery directly from the coeliac trunk and spasm ...
PMC1925057_F1_12321.jpg
What stands out most in this visual?
Case 1 A 41-year-old man presented with upper gastrointestinal bleed. Endoscopy revealed blood coming out from ampulla Fig 1a Axial section of Dual phase CT scan shows hyperdensity (white arrow) within the gallbladder 1b Flush aortogram shows origin of the right hepatic artery directly from the coeliac trunk and spasm ...
PMC1925057_F2_12319.jpg
Describe the main subject of this image.
Case 2 A 55-year-old woman presented with obstructive jaundice and cholangitis for 2 months. Past history of cholecystectomy done 1 year ago. Fig 2a CECT showed mildly dilated intrahepatic radicals (white arrow) with enlarged lymph nodes (black arrow) along the hepatic artery. On exploration mass in CBD with multiple p...
PMC1925057_F2_12320.jpg
Describe the main subject of this image.
Case 2 A 55-year-old woman presented with obstructive jaundice and cholangitis for 2 months. Past history of cholecystectomy done 1 year ago. Fig 2a CECT showed mildly dilated intrahepatic radicals (white arrow) with enlarged lymph nodes (black arrow) along the hepatic artery. On exploration mass in CBD with multiple p...
PMC1925057_F3_12328.jpg
What does this image primarily show?
Case 3 A 56-year-old woman presented with obstructive jaundice (2 months) associated with cholangitis and previous cholecystectomy (8 years ago). Fig 3 a) MRCP done showed dilated intrahepatic radicals with stricture below confluence (white arrow). 3 b) PTBD done to relieve cholangitis shows stricture below confluence ...
PMC1925057_F3_12327.jpg
What key item or scene is captured in this photo?
Case 3 A 56-year-old woman presented with obstructive jaundice (2 months) associated with cholangitis and previous cholecystectomy (8 years ago). Fig 3 a) MRCP done showed dilated intrahepatic radicals with stricture below confluence (white arrow). 3 b) PTBD done to relieve cholangitis shows stricture below confluence ...
PMC1925057_F3_12326.jpg
What does this image primarily show?
Case 3 A 56-year-old woman presented with obstructive jaundice (2 months) associated with cholangitis and previous cholecystectomy (8 years ago). Fig 3 a) MRCP done showed dilated intrahepatic radicals with stricture below confluence (white arrow). 3 b) PTBD done to relieve cholangitis shows stricture below confluence ...
PMC1925057_F3_12325.jpg
What is the central feature of this picture?
Case 3 A 56-year-old woman presented with obstructive jaundice (2 months) associated with cholangitis and previous cholecystectomy (8 years ago). Fig 3 a) MRCP done showed dilated intrahepatic radicals with stricture below confluence (white arrow). 3 b) PTBD done to relieve cholangitis shows stricture below confluence ...
PMC1925058_F1_12329.jpg
Can you identify the primary element in this image?
Laparoscopic view of a necrotic haemorrhagic epiploic appendage.
PMC1925108_F2_12333.jpg
What does this image primarily show?
Expression of von Willebrand factor (vWF), CD31/PECAM-1 and Prox1 in large vessel control cells. Granular intracellular localization of vWF, membranous localization of CD31 and nuclear localization of Prox1 was detected by immunocytology in HUVEC and HAEC. Nuclei were counter-stained with DAPI. One representative stain...
PMC1925108_F2_12330.jpg
What is being portrayed in this visual content?
Expression of von Willebrand factor (vWF), CD31/PECAM-1 and Prox1 in large vessel control cells. Granular intracellular localization of vWF, membranous localization of CD31 and nuclear localization of Prox1 was detected by immunocytology in HUVEC and HAEC. Nuclei were counter-stained with DAPI. One representative stain...
PMC1925108_F2_12332.jpg
What is shown in this image?
Expression of von Willebrand factor (vWF), CD31/PECAM-1 and Prox1 in large vessel control cells. Granular intracellular localization of vWF, membranous localization of CD31 and nuclear localization of Prox1 was detected by immunocytology in HUVEC and HAEC. Nuclei were counter-stained with DAPI. One representative stain...
PMC1925108_F8_12334.jpg
What stands out most in this visual?
Isolation and characterization of LECs from lymphangiomas. Lymphendothelial cells (LECs) from lymphangioma explants isolated by „cell sweeping” were photographed under phase contrast microscopy. a) The cells from patient-A show the typical cobblestone morphology and are contact inhibited (passage 7, magnification, × 40...
PMC1925108_F8_12335.jpg
Describe the main subject of this image.
Isolation and characterization of LECs from lymphangiomas. Lymphendothelial cells (LECs) from lymphangioma explants isolated by „cell sweeping” were photographed under phase contrast microscopy. a) The cells from patient-A show the typical cobblestone morphology and are contact inhibited (passage 7, magnification, × 40...
PMC1925108_F8_12337.jpg
What is shown in this image?
Isolation and characterization of LECs from lymphangiomas. Lymphendothelial cells (LECs) from lymphangioma explants isolated by „cell sweeping” were photographed under phase contrast microscopy. a) The cells from patient-A show the typical cobblestone morphology and are contact inhibited (passage 7, magnification, × 40...
PMC1925116_F1_12344.jpg
What does this image primarily show?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12342.jpg
What is the principal component of this image?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12347.jpg
What is the principal component of this image?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12341.jpg
Describe the main subject of this image.
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12340.jpg
What key item or scene is captured in this photo?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12345.jpg
Can you identify the primary element in this image?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925116_F1_12338.jpg
What's the most prominent thing you notice in this picture?
Top row: DWI sequences of MRI brain obtained at day #3 after admission showing abnormal signal in the cerebellum (a), globus pallidus bilaterally (c), motor cortex (d and e). Bottom row: DWI sequences of MRI brain at day #18 after admission showing more attenuated and confluent cerebellar lesions (f), new hyperintensit...
PMC1925147_pone-0000685-g001_12348.jpg
What is being portrayed in this visual content?
Slit lamp image of the right cornea from a 50-year old affected member of family 105, demonstrating a “bull's eye” morphology of central and peripheral corneal clouding associated with a relatively spared mid-peripheral zone.Central subepithelial crystalline deposits and prominent corneal arcus are also present.
PMC1929081_F4_12363.jpg
Describe the main subject of this image.
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12354.jpg
What key item or scene is captured in this photo?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12361.jpg
What is the focal point of this photograph?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12367.jpg
What key item or scene is captured in this photo?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12360.jpg
What can you see in this picture?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12352.jpg
What is the principal component of this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12359.jpg
Describe the main subject of this image.
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12358.jpg
What is the principal component of this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12356.jpg
What is the principal component of this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12355.jpg
What key item or scene is captured in this photo?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12365.jpg
What is the principal component of this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12368.jpg
Can you identify the primary element in this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12351.jpg
What is the main focus of this visual representation?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12366.jpg
What is the focal point of this photograph?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12353.jpg
Describe the main subject of this image.
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929081_F4_12357.jpg
What is the dominant medical problem in this image?
Diffusion Tensor Imaging: Whole-Brain Fractional Anisotropy Maps of normal control.
PMC1929085_F5_12370.jpg
What is the focal point of this photograph?
Histological sections from a 35 year-old patient with bilateral palpable breast masses. A representative hematoxylin and eosin section of the left breast mass core needle biopsy specimen is shown at 600 × magnification. The tumor is composed of diffuse sheets of small polygonal cells with nuclear molding, scant cytopla...
PMC1929085_F6_12369.jpg
What is the principal component of this image?
Sections of the left breast mass core needle biopsy specimen shown in Figure 5 were positive for chromogranin A immunostaining.
PMC1929085_F7_12371.jpg
What key item or scene is captured in this photo?
Sections of the left breast mass core needle biopsy specimen shown in Figure 5 were positive for synaptophysin immunostaining. Identical histological features were seen on the contralateral breast core biopsy specimen. The immunostain results suggested a neuroendocrine carcinoma, rather than a primary breast adenocarci...
PMC1929103_F4_12384.jpg
What object or scene is depicted here?
Tumour formation in the mouse mammary gland. One million human mammary epithelial cells (HMECs) expressing oestrogen receptor alpha (ERα), BMI1, TERT and MYC were injected into the inguinal mammary fat pads of NOD/SCID mice; 2 × 105 HMFs were injected simultaneously with the HMECs to promote engraftment. (a-c) In the a...
PMC1929103_F4_12382.jpg
What object or scene is depicted here?
Tumour formation in the mouse mammary gland. One million human mammary epithelial cells (HMECs) expressing oestrogen receptor alpha (ERα), BMI1, TERT and MYC were injected into the inguinal mammary fat pads of NOD/SCID mice; 2 × 105 HMFs were injected simultaneously with the HMECs to promote engraftment. (a-c) In the a...
PMC1929103_F4_12383.jpg
What key item or scene is captured in this photo?
Tumour formation in the mouse mammary gland. One million human mammary epithelial cells (HMECs) expressing oestrogen receptor alpha (ERα), BMI1, TERT and MYC were injected into the inguinal mammary fat pads of NOD/SCID mice; 2 × 105 HMFs were injected simultaneously with the HMECs to promote engraftment. (a-c) In the a...
PMC1929103_F4_12385.jpg
Can you identify the primary element in this image?
Tumour formation in the mouse mammary gland. One million human mammary epithelial cells (HMECs) expressing oestrogen receptor alpha (ERα), BMI1, TERT and MYC were injected into the inguinal mammary fat pads of NOD/SCID mice; 2 × 105 HMFs were injected simultaneously with the HMECs to promote engraftment. (a-c) In the a...