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PMC1929103_F4_12378.jpg
What can you see in this picture?
Tumour formation in the mouse mammary gland. One million human mammary epithelial cells (HMECs) expressing oestrogen receptor alpha (ERα), BMI1, TERT and MYC were injected into the inguinal mammary fat pads of NOD/SCID mice; 2 × 105 HMFs were injected simultaneously with the HMECs to promote engraftment. (a-c) In the a...
PMC1929103_F8_12373.jpg
What is shown in this image?
Response to anti-oestrogen therapy. (a) Tumour cells were recovered from a mouse, then grown in the presence of oestradiol (E) or fulvestrant (F). (b,c) Mammary glands of mice that received an oestrogen pellet before injection of the tumour cells, followed by either no additional treatment (b) or weekly subcutaneous in...
PMC1929103_F8_12377.jpg
Describe the main subject of this image.
Response to anti-oestrogen therapy. (a) Tumour cells were recovered from a mouse, then grown in the presence of oestradiol (E) or fulvestrant (F). (b,c) Mammary glands of mice that received an oestrogen pellet before injection of the tumour cells, followed by either no additional treatment (b) or weekly subcutaneous in...
PMC1929103_F8_12372.jpg
What is the focal point of this photograph?
Response to anti-oestrogen therapy. (a) Tumour cells were recovered from a mouse, then grown in the presence of oestradiol (E) or fulvestrant (F). (b,c) Mammary glands of mice that received an oestrogen pellet before injection of the tumour cells, followed by either no additional treatment (b) or weekly subcutaneous in...
PMC1929103_F9_12393.jpg
What's the most prominent thing you notice in this picture?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12397.jpg
What is shown in this image?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12389.jpg
What key item or scene is captured in this photo?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12394.jpg
What is the central feature of this picture?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12388.jpg
What is the dominant medical problem in this image?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12391.jpg
Describe the main subject of this image.
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929103_F9_12390.jpg
What key item or scene is captured in this photo?
Metastasis formation after injection of transformed cells into the mammary gland. Metastases were observed from 30 to 90 days after injection of oestrogen receptor alpha (ERα)/BMI1/TERT/MYC-transformed human mammary epithelial cells (HMECs). (a-e) Peritoneal metastases 90 days after injection. (f-j) liver metastases 30...
PMC1929122_F1_12405.jpg
What is the core subject represented in this visual?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12402.jpg
What is being portrayed in this visual content?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12401.jpg
What is shown in this image?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12406.jpg
What is the focal point of this photograph?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12404.jpg
What is the core subject represented in this visual?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12407.jpg
What is shown in this image?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929122_F1_12403.jpg
Can you identify the primary element in this image?
Volumetric MRI and coregistered FDG-PET: (a) MRI Extracted whole brain is segmented into (b) MRI right and left cerebral hemispheres, in turn thresholded into (c) MRI right and left cerebral cortices. Coregistration of the (d) FDG-PET whole brain allows accurate anatomical definition on the metabolic studies of, for ex...
PMC1929154_F6_12410.jpg
What can you see in this picture?
Expression of ectoderm markers in normal, lithium-treated, and zinc-treated embryos. Shown are whole-mount in situ hybridizations (WISHs) of ectodermal marker genes on blastula stage (columns 1, 3, and 5) and gastrula stage (columns 2, 4, and 6) sea urchin embryos. The genes under considerations are indicated on the ri...
PMC1929154_F6_12409.jpg
What does this image primarily show?
Expression of ectoderm markers in normal, lithium-treated, and zinc-treated embryos. Shown are whole-mount in situ hybridizations (WISHs) of ectodermal marker genes on blastula stage (columns 1, 3, and 5) and gastrula stage (columns 2, 4, and 6) sea urchin embryos. The genes under considerations are indicated on the ri...
PMC1931589_F4_12415.jpg
What is the focal point of this photograph?
Beaded appearance of P2Y1 receptor immunostaining. Sagital sections of P21 rat cerebellar cortex were processed for triple immunofluorescence analysis and visualized by confocal microscopy. Rabbit anti-P2Y1 (red Cy3 immunofluorescence) was used in combination with mouse anti-synaptophysin, a marker for synaptic structu...
PMC1931589_F4_12414.jpg
What is the principal component of this image?
Beaded appearance of P2Y1 receptor immunostaining. Sagital sections of P21 rat cerebellar cortex were processed for triple immunofluorescence analysis and visualized by confocal microscopy. Rabbit anti-P2Y1 (red Cy3 immunofluorescence) was used in combination with mouse anti-synaptophysin, a marker for synaptic structu...
PMC1931589_F4_12413.jpg
Can you identify the primary element in this image?
Beaded appearance of P2Y1 receptor immunostaining. Sagital sections of P21 rat cerebellar cortex were processed for triple immunofluorescence analysis and visualized by confocal microscopy. Rabbit anti-P2Y1 (red Cy3 immunofluorescence) was used in combination with mouse anti-synaptophysin, a marker for synaptic structu...
PMC1931604_F2_12421.jpg
What is the principal component of this image?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12424.jpg
What is the dominant medical problem in this image?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12422.jpg
What object or scene is depicted here?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12423.jpg
What is the principal component of this image?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12418.jpg
What is the core subject represented in this visual?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12417.jpg
What can you see in this picture?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F2_12419.jpg
What can you see in this picture?
VP22 enhanced microdystrophin gene expression and distribution in mdx mice. (A) The effect of VP22 was reflected in the level of microdystrophin expression in pAMICDYS (a) and pAVP22-MICDYS (b) injected the left TA muscles. Microdystrophin -positive fibers were detected in both groups, but the number of microdystrophin...
PMC1931604_F4_12428.jpg
What's the most prominent thing you notice in this picture?
VP22-mediated microdystrophin gene expression was more efficient in reducing central nucleation in mdx mice. Histological analysis the left TA of mdx mice injected by pAMICDYS, pAVP22-MICDYS and the right TA injected by PBS. Shown are H&E-stained TA muscle cross sections from post-injection 2 weeks (A, B, C), post-inje...
PMC1931604_F4_12429.jpg
What is shown in this image?
VP22-mediated microdystrophin gene expression was more efficient in reducing central nucleation in mdx mice. Histological analysis the left TA of mdx mice injected by pAMICDYS, pAVP22-MICDYS and the right TA injected by PBS. Shown are H&E-stained TA muscle cross sections from post-injection 2 weeks (A, B, C), post-inje...
PMC1931604_F4_12430.jpg
What's the most prominent thing you notice in this picture?
VP22-mediated microdystrophin gene expression was more efficient in reducing central nucleation in mdx mice. Histological analysis the left TA of mdx mice injected by pAMICDYS, pAVP22-MICDYS and the right TA injected by PBS. Shown are H&E-stained TA muscle cross sections from post-injection 2 weeks (A, B, C), post-inje...
PMC1931604_F4_12431.jpg
What's the most prominent thing you notice in this picture?
VP22-mediated microdystrophin gene expression was more efficient in reducing central nucleation in mdx mice. Histological analysis the left TA of mdx mice injected by pAMICDYS, pAVP22-MICDYS and the right TA injected by PBS. Shown are H&E-stained TA muscle cross sections from post-injection 2 weeks (A, B, C), post-inje...
PMC1931604_F4_12434.jpg
Describe the main subject of this image.
VP22-mediated microdystrophin gene expression was more efficient in reducing central nucleation in mdx mice. Histological analysis the left TA of mdx mice injected by pAMICDYS, pAVP22-MICDYS and the right TA injected by PBS. Shown are H&E-stained TA muscle cross sections from post-injection 2 weeks (A, B, C), post-inje...
PMC1931604_F6_12437.jpg
What object or scene is depicted here?
Immunohistochemical staining of microdystrophin in the diaphragm muscle from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The diaphragm muscle with C57BL/10 mouse (A); the diaphragm muscle with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were...
PMC1931604_F6_12436.jpg
Can you identify the primary element in this image?
Immunohistochemical staining of microdystrophin in the diaphragm muscle from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The diaphragm muscle with C57BL/10 mouse (A); the diaphragm muscle with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were...
PMC1931604_F6_12435.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical staining of microdystrophin in the diaphragm muscle from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The diaphragm muscle with C57BL/10 mouse (A); the diaphragm muscle with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were...
PMC1931604_F7_12425.jpg
What is shown in this image?
Immunohistochemical staining of microdystrophin in myocardium from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The myocardium with C57BL/10 mouse (A); the myocardium with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were only detected in grou...
PMC1931604_F7_12426.jpg
What key item or scene is captured in this photo?
Immunohistochemical staining of microdystrophin in myocardium from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The myocardium with C57BL/10 mouse (A); the myocardium with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were only detected in grou...
PMC1931604_F7_12427.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical staining of microdystrophin in myocardium from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The myocardium with C57BL/10 mouse (A); the myocardium with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were only detected in grou...
PMC1931605_F3_12446.jpg
Can you identify the primary element in this image?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12442.jpg
What does this image primarily show?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12448.jpg
What is the main focus of this visual representation?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12439.jpg
What is the core subject represented in this visual?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12445.jpg
What stands out most in this visual?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12447.jpg
Describe the main subject of this image.
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12444.jpg
What object or scene is depicted here?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12440.jpg
What stands out most in this visual?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1931605_F3_12449.jpg
What stands out most in this visual?
TRPM5 is specifically expressed in brush cells of the respiratory system. Detection of solitary TRPM5-expressing cells in the mouse respiratory epithelium of nose (indicated by arrows in (A)), trachea (B) and bronchus (C). Overlays of TRPM5 fluorescence with the corresponding DIC images are shown. The inset in (C) show...
PMC1933421_F6_12460.jpg
What is the dominant medical problem in this image?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12465.jpg
What key item or scene is captured in this photo?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12466.jpg
What stands out most in this visual?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12463.jpg
What is the principal component of this image?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12464.jpg
What is the focal point of this photograph?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12459.jpg
Describe the main subject of this image.
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12458.jpg
What is the principal component of this image?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12467.jpg
What stands out most in this visual?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F6_12470.jpg
What is the principal component of this image?
Manipulation of PKD activity causes retina degeneration. A) Eyes of control flies have externally a smooth and regular appearance (left column). Tangential sections reveal the underlying, semi-crystalline architecture of the facets (center column). Seven photoreceptor cells can be distinguished by the centrally located...
PMC1933421_F7_12451.jpg
What is the principal component of this image?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933421_F7_12450.jpg
What is the core subject represented in this visual?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933421_F7_12453.jpg
What is the focal point of this photograph?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933421_F7_12452.jpg
What can you see in this picture?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933421_F7_12456.jpg
What is the dominant medical problem in this image?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933421_F7_12454.jpg
What is the main focus of this visual representation?
Dependence of retinal degeneration on light and age. Flies were raised in twelve-hour day-night cycle (left column; labelled with black and white bar) or in complete darkness (right column; black bar) and aged for several days at 25°C. Time points shown: 3d, 0–3 days after hatching; 14d, 10–14 days after hatching. Enla...
PMC1933423_F6_12474.jpg
Can you identify the primary element in this image?
Co-localization of hairy1, sap18and sin3a mRNA expression in the prospective somitic territory and somites. (A) Whole mount in situ hybridization with the probe indicated on top was performed in chick embryos in somitogenesis developmental stages (upper panel). The lower panel is an amplified view of the rostral PSM an...
PMC1933423_F6_12472.jpg
What is shown in this image?
Co-localization of hairy1, sap18and sin3a mRNA expression in the prospective somitic territory and somites. (A) Whole mount in situ hybridization with the probe indicated on top was performed in chick embryos in somitogenesis developmental stages (upper panel). The lower panel is an amplified view of the rostral PSM an...
PMC1933423_F6_12471.jpg
What stands out most in this visual?
Co-localization of hairy1, sap18and sin3a mRNA expression in the prospective somitic territory and somites. (A) Whole mount in situ hybridization with the probe indicated on top was performed in chick embryos in somitogenesis developmental stages (upper panel). The lower panel is an amplified view of the rostral PSM an...
PMC1933425_F4_12476.jpg
Describe the main subject of this image.
Immunocytochemical detection. The immunocytochemical detection of PrP on CCRF-CEM cells with the phage antibody MA3.B4 is shown. In A and B the immunostaining at two different magnification, in C and D the reactivity of CCRF-CEM cells with two distinct irrelevant phage antibodies (anti glucose oxidase and anti tetanus ...
PMC1933425_F4_12478.jpg
Describe the main subject of this image.
Immunocytochemical detection. The immunocytochemical detection of PrP on CCRF-CEM cells with the phage antibody MA3.B4 is shown. In A and B the immunostaining at two different magnification, in C and D the reactivity of CCRF-CEM cells with two distinct irrelevant phage antibodies (anti glucose oxidase and anti tetanus ...
PMC1933425_F4_12477.jpg
What is being portrayed in this visual content?
Immunocytochemical detection. The immunocytochemical detection of PrP on CCRF-CEM cells with the phage antibody MA3.B4 is shown. In A and B the immunostaining at two different magnification, in C and D the reactivity of CCRF-CEM cells with two distinct irrelevant phage antibodies (anti glucose oxidase and anti tetanus ...
PMC1933451_ppat-0030101-g001_12480.jpg
What is the core subject represented in this visual?
Dead C. elegans Nematodes Infected by C. albicans Filamentation is instrumental for Candida virulence in mammals and is also involved in the killing of C. elegans [20]. The four panels show consequences of infecting C. elegans glp-4;sek-1 animals with C. albicans and then moving them into pathogen-free liquid medium. T...
PMC1933451_ppat-0030101-g001_12481.jpg
What is the central feature of this picture?
Dead C. elegans Nematodes Infected by C. albicans Filamentation is instrumental for Candida virulence in mammals and is also involved in the killing of C. elegans [20]. The four panels show consequences of infecting C. elegans glp-4;sek-1 animals with C. albicans and then moving them into pathogen-free liquid medium. T...
PMC1933451_ppat-0030101-g001_12482.jpg
What object or scene is depicted here?
Dead C. elegans Nematodes Infected by C. albicans Filamentation is instrumental for Candida virulence in mammals and is also involved in the killing of C. elegans [20]. The four panels show consequences of infecting C. elegans glp-4;sek-1 animals with C. albicans and then moving them into pathogen-free liquid medium. T...
PMC1933541_F1_12483.jpg
What is the principal component of this image?
Endosopic view of the opening site of CBD in the duodenal bulb. Slit – like ectopic openings of common bile duct (upper hole) and pancreatic duct (lower hole) with guide-wires inserted for the better demonstration.
PMC1933541_F2_12484.jpg
What key item or scene is captured in this photo?
View of deformed bulbus due to chronic ulceration. Wall deformity and narrowing of the lumen (arrow heads). Arrows indicate openings of CBD (upper) and PD (lower).
PMC1933541_F3_12486.jpg
What is the principal component of this image?
Cholangiography of a typical case. Characteristic appearance of CBD with tapered and hook-shaped distal ending in a patient with ectopic opening to the duodenal bulb. Note the dilation at CBD and intrahepatic bile ducts.
PMC1933541_F4_12485.jpg
What is being portrayed in this visual content?
Cholangiography of a case without dilation in CBD. CBD and PD in normal diameter entering to the duodenal bulb separately. The hook – shape and tapering of the distal end of the CBD is now slightly perceived when it's in normal diameter
PMC1933541_F5_12488.jpg
What key item or scene is captured in this photo?
Cholangiography of a case with "Real Stricture". A dilated CBD and PD separately opened to the duodenal bulb. Note the distal end of the CBD narrowed critically. Despite the absence of a stone, a 11.5 mm diameter inflated extraction balloon wasn't pulled-out.(real stricture).
PMC1933541_F6_12487.jpg
What is the central feature of this picture?
Pneumobilia. Computarized Tomography appearance of air in the intrahepatic bile ducts.
PMC1933546_F1_12489.jpg
What object or scene is depicted here?
Immunohistochemical study of the expression of Sialyl Lewis x in canine malignant mammary tumours. A. Solid carcinoma; >75% of sLex expression; ×400 B. Carcinosarcoma; 25–50% of cells stained; ×400.
PMC1933546_F1_12490.jpg
What does this image primarily show?
Immunohistochemical study of the expression of Sialyl Lewis x in canine malignant mammary tumours. A. Solid carcinoma; >75% of sLex expression; ×400 B. Carcinosarcoma; 25–50% of cells stained; ×400.
PMC1933593_pone-0000699-g003_12493.jpg
What is the principal component of this image?
Imaging performance and resolution.a) Transmitted light image of a neuron in acute rat brain slice. Video-rate acquisition permits patch-clamping without the use of a separate camera. b) Fluorescence image of a cortical L2/3 pyramidal cell filled with the fluorescent dye FM 4–64. Inset: zoom onto the 10×10 µm area outl...
PMC1933593_pone-0000699-g003_12492.jpg
What is the focal point of this photograph?
Imaging performance and resolution.a) Transmitted light image of a neuron in acute rat brain slice. Video-rate acquisition permits patch-clamping without the use of a separate camera. b) Fluorescence image of a cortical L2/3 pyramidal cell filled with the fluorescent dye FM 4–64. Inset: zoom onto the 10×10 µm area outl...
PMC1933593_pone-0000699-g003_12491.jpg
What is shown in this image?
Imaging performance and resolution.a) Transmitted light image of a neuron in acute rat brain slice. Video-rate acquisition permits patch-clamping without the use of a separate camera. b) Fluorescence image of a cortical L2/3 pyramidal cell filled with the fluorescent dye FM 4–64. Inset: zoom onto the 10×10 µm area outl...
PMC1934365_F2_12495.jpg
What is the main focus of this visual representation?
CT scan showing extensive involvement of the main pulmonary artery and into the right trunk.
PMC1934393_pgen-0030118-g001_12500.jpg
What is being portrayed in this visual content?
Comparison of Skull ImagePresented is a volume rendering of skull forms of C57BL/6 wild-type mice of different sexes and ages (left panel) and DDR2−/−, DDR1−/−, and DDR2+/− mice (right panel). Displayed are distances and representative features of the skeleton of the head viewed from the right side. D 1 represents the ...
PMC1934393_pgen-0030118-g001_12499.jpg
Describe the main subject of this image.
Comparison of Skull ImagePresented is a volume rendering of skull forms of C57BL/6 wild-type mice of different sexes and ages (left panel) and DDR2−/−, DDR1−/−, and DDR2+/− mice (right panel). Displayed are distances and representative features of the skeleton of the head viewed from the right side. D 1 represents the ...
PMC1934393_pgen-0030118-g001_12498.jpg
Describe the main subject of this image.
Comparison of Skull ImagePresented is a volume rendering of skull forms of C57BL/6 wild-type mice of different sexes and ages (left panel) and DDR2−/−, DDR1−/−, and DDR2+/− mice (right panel). Displayed are distances and representative features of the skeleton of the head viewed from the right side. D 1 represents the ...
PMC1934393_pgen-0030118-g001_12501.jpg
What is the core subject represented in this visual?
Comparison of Skull ImagePresented is a volume rendering of skull forms of C57BL/6 wild-type mice of different sexes and ages (left panel) and DDR2−/−, DDR1−/−, and DDR2+/− mice (right panel). Displayed are distances and representative features of the skeleton of the head viewed from the right side. D 1 represents the ...
PMC1934393_pgen-0030118-g001_12497.jpg
What key item or scene is captured in this photo?
Comparison of Skull ImagePresented is a volume rendering of skull forms of C57BL/6 wild-type mice of different sexes and ages (left panel) and DDR2−/−, DDR1−/−, and DDR2+/− mice (right panel). Displayed are distances and representative features of the skeleton of the head viewed from the right side. D 1 represents the ...
PMC1934902_F3_12503.jpg
What's the most prominent thing you notice in this picture?
CT scan of chest showing enlarged para-aortic lymph node.
PMC1934902_F4_12504.jpg
What is the main focus of this visual representation?
Biopsy of preaortic lymph node showing monomorphic moulded neoplastic lymphoid cells with large pale macrophage "stars".
PMC1934909_F1_12505.jpg
What's the most prominent thing you notice in this picture?
CT scan showing a roundish, hypodense left fronto-parietal mass with a thinness satellite parietal bone (arrow). A contrast enhanced CT scan reveals any septa inside the tumour which give it a polycystic aspect.
PMC1934920_F1_12506.jpg
What does this image primarily show?
Thin layer preparation, vaginal melanoma. Note the dispersed proliferation of highly atypical medium sized cells with ovoid or kidney-shaped, nucleolated nuclei. The neoplastic cells display a scarce to moderate amount of greyish granular cytoplasm with peripheral condensation and cytoplasmic projections suggestive of ...
PMC1934920_F1_12507.jpg
What stands out most in this visual?
Thin layer preparation, vaginal melanoma. Note the dispersed proliferation of highly atypical medium sized cells with ovoid or kidney-shaped, nucleolated nuclei. The neoplastic cells display a scarce to moderate amount of greyish granular cytoplasm with peripheral condensation and cytoplasmic projections suggestive of ...
PMC1934920_F4_12509.jpg
What is the focal point of this photograph?
Vaginal melanoma, cross-section of surgical sample. A 5 × 4 × 4 cm whitish solid mass can be observed lined by partly ulcerated vaginal mucosa. The left cervical fornix is visible in the upper center of the picture.
PMC1934920_F5_12508.jpg
What is being portrayed in this visual content?
Vaginal melanoma: histopathological section showing an infiltrating dispersed cell population with alveolar pattern of growth (Hematoxylin and Eosin, 250×, original magnification).
PMC1934933_pone-0000714-g001_12515.jpg
Describe the main subject of this image.
3D time-lapse series of muscle development in a Ciona intestinalis embryo visualized by electroporation with the sna>Venus plasmid.(A) gastrula, (B) neural plate, (C) neurula, (D) early tailbud, (E) mid tailbud, and (F) late tailbud stages from a single embryo are shown. The anterior of the embryo is to the left, poste...
PMC1934933_pone-0000714-g001_12514.jpg
What is the focal point of this photograph?
3D time-lapse series of muscle development in a Ciona intestinalis embryo visualized by electroporation with the sna>Venus plasmid.(A) gastrula, (B) neural plate, (C) neurula, (D) early tailbud, (E) mid tailbud, and (F) late tailbud stages from a single embryo are shown. The anterior of the embryo is to the left, poste...