text stringlengths 26 3.6k | page_title stringlengths 1 71 | source stringclasses 1 value | token_count int64 10 512 | id stringlengths 2 8 | url stringlengths 31 117 | topic stringclasses 4 values | section stringlengths 4 49 ⌀ | sublist stringclasses 9 values |
|---|---|---|---|---|---|---|---|---|
Disks
Some very young star-forming regions, typically younger than 5 million years, sometimes contain isolated planetary-mass objects with infrared excess and signs of accretion. Most well known is the iPMO OTS 44 discovered to have a disk and being located in Chamaeleon I. Charmaeleon I and II have other candidate iPMOs with disks. Other star-forming regions with iPMOs with disks or accretion are Lupus I, Rho Ophiuchi Cloud Complex, Sigma Orionis cluster, Orion Nebula, Taurus, NGC 1333 and IC 348. A large survey of disks around brown dwarfs and iPMOs with ALMA found that these disks are not massive enough to form earth-mass planets. There is still the possibility that the disks already have formed planets. Studies of red dwarfs have shown that some have gas-rich disks at a relative old age. These disks were dubbed Peter Pan Disks and this trend could continue into the planetary-mass regime. One Peter Pan disk is the 45 Myr old brown dwarf 2MASS J02265658-5327032 with a mass of about 13.7 , which is close to the planetary-mass regime. Recent studies of the nearby planetary-mass object 2MASS J11151597+1937266 found that this nearby iPMO is surrounded by a disk. It shows signs of accretion from the disk and also infrared excess.
Formation like a planet
Ejected planets are predicted to be mostly low-mass (<30 Figure 1 Ma et al.) and their mean mass depends on the mass of their host star. Simulations by Ma et al. did show that 17.5% of 1 stars eject a total of 16.8 per star with a typical (median) mass of 0.8 for an individual free-floating planet (FFP). For lower mass red dwarfs with a mass of 0.3 12% of stars eject a total of 5.1 per star with a typical mass of 0.3 for an individual FFP. | Rogue planet | Wikipedia | 417 | 558397 | https://en.wikipedia.org/wiki/Rogue%20planet | Physical sciences | Planetary science | Astronomy |
Hong et al. predicted that exomoons can be scattered by planet-planet interactions and become ejected exomoons. Higher mass (0.3-1 ) ejected FFP are predicted to be possible, but they are also predicted to be rare. Ejection of a planet can occur via planet-planet scatter or due a stellar flyby. Another possibility is the ejection of a fragment of a disk that then forms into a planetary-mass object. Another suggested scenario is the ejection of planets in a tilted circumbinary orbit. Interactions with the central binary and the planets with each other can lead to the ejection of the lower-mass planet in the system.
Other scenarios
If a stellar or brown dwarf embryo experiences a halted accretion, it could remain low-mass enough to become a planetary-mass object. Such a halted accretion could occur if the embryo is ejected or if its circumstellar disk experiences photoevaporation near O-stars. Objects that formed via the ejected embryo scenario would have smaller or no disk and the fraction of binaries decreases for such objects. It could also be that free-floating planetary-mass objects for from a combination of scenarios.
Fate
Most isolated planetary-mass objects will float in interstellar space forever.
Some iPMOs will have a close encounter with a planetary system. This rare encounter can have three outcomes: The iPMO will remain unbound, it could be weakly bound to the star, or it could "kick out" the exoplanet, replacing it. Simulations have shown that the vast majority of these encounters result in a capture event with the iPMO being weakly bound with a low gravitational binding energy and an elongated highly eccentric orbit. These orbits are not stable and 90% of these objects gain energy due to planet-planet encounters and are ejected back into interstellar space. Only 1% of all stars will experience this temporary capture.
Warmth
Interstellar planets generate little heat and are not heated by a star. However, in 1998, David J. Stevenson theorized that some planet-sized objects adrift in interstellar space might sustain a thick atmosphere that would not freeze out. He proposed that these atmospheres would be preserved by the pressure-induced far-infrared radiation opacity of a thick hydrogen-containing atmosphere. | Rogue planet | Wikipedia | 472 | 558397 | https://en.wikipedia.org/wiki/Rogue%20planet | Physical sciences | Planetary science | Astronomy |
During planetary-system formation, several small protoplanetary bodies may be ejected from the system. An ejected body would receive less of the stellar-generated ultraviolet light that can strip away the lighter elements of its atmosphere. Even an Earth-sized body would have enough gravity to prevent the escape of the hydrogen and helium in its atmosphere. In an Earth-sized object the geothermal energy from residual core radioisotope decay could maintain a surface temperature above the melting point of water, allowing liquid-water oceans to exist. These planets are likely to remain geologically active for long periods. If they have geodynamo-created protective magnetospheres and sea floor volcanism, hydrothermal vents could provide energy for life. These bodies would be difficult to detect because of their weak thermal microwave radiation emissions, although reflected solar radiation and far-infrared thermal emissions may be detectable from an object that is less than 1,000 astronomical units from Earth. Around five percent of Earth-sized ejected planets with Moon-sized natural satellites would retain their satellites after ejection. A large satellite would be a source of significant geological tidal heating.
List
The table below lists rogue planets, confirmed or suspected, that have been discovered. It is yet unknown whether these planets were ejected from orbiting a star or else formed on their own as sub-brown dwarfs. Whether exceptionally low-mass rogue planets (such as OGLE-2012-BLG-1323 and KMT-2019-BLG-2073) are even capable of being formed on their own is currently unknown.
Discovered via direct imaging
These objects were discovered with the direct imaging method. Many were discovered in young star-clusters or stellar associations and a few old are known (such as WISE 0855−0714). List is sorted after discovery year.
Discovered via microlensing
These objects were discovered via microlensing. Rogue planets discovered via microlensing can only be studied by the lensing event. Some of them could also be exoplanets in a wide orbit around an unseen star.
Discovered via transit | Rogue planet | Wikipedia | 420 | 558397 | https://en.wikipedia.org/wiki/Rogue%20planet | Physical sciences | Planetary science | Astronomy |
The natural environment or natural world encompasses all biotic and abiotic things occurring naturally, meaning in this case not artificial. The term is most often applied to Earth or some parts of Earth. This environment encompasses the interaction of all living species, climate, weather and natural resources that affect human survival and economic activity.
The concept of the natural environment can be distinguished as components:
Complete ecological units that function as natural systems without massive civilized human intervention, including all vegetation, microorganisms, soil, rocks, plateaus, mountains, the atmosphere and natural phenomena that occur within their boundaries and their nature.
Universal natural resources and physical phenomena that lack clear-cut boundaries, such as air, water and climate, as well as energy, radiation, electric charge and magnetism, not originating from civilized human actions.
In contrast to the natural environment is the built environment. Built environments are where humans have fundamentally transformed landscapes such as urban settings and agricultural land conversion, the natural environment is greatly changed into a simplified human environment. Even acts which seem less extreme, such as building a mud hut or a photovoltaic system in the desert, the modified environment becomes an artificial one. Though many animals build things to provide a better environment for themselves, they are not human, hence beaver dams and the works of mound-building termites are thought of as natural.
People cannot find absolutely natural environments on Earth,naturalness usually varies in a continuum, from 100% natural in one extreme to 0% natural in the other. The massive environmental changes of humanity in the Anthropocene have fundamentally effected all natural environments including: climate change, biodiversity loss and pollution from plastic and other chemicals in the air and water. More precisely, we can consider the different aspects or components of an environment, and see that their degree of naturalness is not uniform. If, for instance, in an agricultural field, the mineralogic composition and the structure of its soil are similar to those of an undisturbed forest soil, but the structure is quite different.
Composition | Natural environment | Wikipedia | 410 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Earth science generally recognizes four spheres, the lithosphere, the hydrosphere, the atmosphere and the biosphere as correspondent to rocks, water, air and life respectively. Some scientists include as part of the spheres of the Earth, the cryosphere (corresponding to ice) as a distinct portion of the hydrosphere, as well as the pedosphere (to soil) as an active and intermixed sphere. Earth science (also known as geoscience, the geographical sciences or the Earth Sciences), is an all-embracing term for the sciences related to the planet Earth. There are four major disciplines in earth sciences, namely geography, geology, geophysics and geodesy. These major disciplines use physics, chemistry, biology, chronology and mathematics to build a qualitative and quantitative understanding of the principal areas or spheres of Earth.
Geological activity
The Earth's crust or lithosphere, is the outermost solid surface of the planet and is chemically, physically and mechanically different from underlying mantle. It has been generated greatly by igneous processes in which magma cools and solidifies to form solid rock. Beneath the lithosphere lies the mantle which is heated by the decay of radioactive elements. The mantle though solid is in a state of rheic convection. This convection process causes the lithospheric plates to move, albeit slowly. The resulting process is known as plate tectonics. Volcanoes result primarily from the melting of subducted crust material or of rising mantle at mid-ocean ridges and mantle plumes.
Water on Earth
Most water is found in various kinds of natural body of water.
Oceans | Natural environment | Wikipedia | 330 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
An ocean is a major body of saline water and a component of the hydrosphere. Approximately 71% of the surface of the Earth (an area of some 362 million square kilometers) is covered by ocean, a continuous body of water that is customarily divided into several principal oceans and smaller seas. More than half of this area is over 3,000 meters (9,800 ft) deep. Average oceanic salinity is around 35 parts per thousand (ppt) (3.5%), and nearly all seawater has a salinity in the range of 30 to 38 ppt. Though generally recognized as several separate oceans, these waters comprise one global, interconnected body of salt water often referred to as the World Ocean or global ocean. The deep seabeds are more than half the Earth's surface, and are among the least-modified natural environments. The major oceanic divisions are defined in part by the continents, various archipelagos and other criteria, these divisions are : (in descending order of size) the Pacific Ocean, the Atlantic Ocean, the Indian Ocean, the Southern Ocean and the Arctic Ocean.
Rivers
A river is a natural watercourse, usually freshwater, flowing toward an ocean, a lake, a sea or another river. A few rivers simply flow into the ground and dry up completely without reaching another body of water.
The water in a river is usually in a channel, made up of a stream bed between banks. In larger rivers there is often also a wider floodplain shaped by waters over-topping the channel. Flood plains may be very wide in relation to the size of the river channel. Rivers are a part of the hydrological cycle. Water within a river is generally collected from precipitation through surface runoff, groundwater recharge, springs and the release of water stored in glaciers and snowpacks.
Small rivers may also be called by several other names, including stream, creek and brook. Their current is confined within a bed and stream banks. Streams play an important corridor role in connecting fragmented habitats and thus in conserving biodiversity. The study of streams and waterways in general is known as surface hydrology.
Lakes
A lake (from Latin lacus) is a terrain feature, a body of water that is localized to the bottom of basin. A body of water is considered a lake when it is inland, is not part of an ocean and is larger and deeper than a pond. | Natural environment | Wikipedia | 491 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Natural lakes on Earth are generally found in mountainous areas, rift zones and areas with ongoing or recent glaciation. Other lakes are found in endorheic basins or along the courses of mature rivers. In some parts of the world, there are many lakes because of chaotic drainage patterns left over from the last ice age. All lakes are temporary over geologic time scales, as they will slowly fill in with sediments or spill out of the basin containing them.
Ponds
A pond is a body of standing water, either natural or human-made, that is usually smaller than a lake. A wide variety of human-made bodies of water are classified as ponds, including water gardens designed for aesthetic ornamentation, fish ponds designed for commercial fish breeding and solar ponds designed to store thermal energy. Ponds and lakes are distinguished from streams by their current speed. While currents in streams are easily observed, ponds and lakes possess thermally driven micro-currents and moderate wind-driven currents. These features distinguish a pond from many other aquatic terrain features, such as stream pools and tide pools.
Human impact on water
Humans impact the water in different ways such as modifying rivers (through dams and stream channelization), urbanization and deforestation. These impact lake levels, groundwater conditions, water pollution, thermal pollution, and marine pollution. Humans modify rivers by using direct channel manipulation. We build dams and reservoirs and manipulate the direction of the rivers and water path. Dams can usefully create reservoirs and hydroelectric power. However, reservoirs and dams may negatively impact the environment and wildlife. Dams stop fish migration and the movement of organisms downstream. Urbanization affects the environment because of deforestation and changing lake levels, groundwater conditions, etc. Deforestation and urbanization go hand in hand. Deforestation may cause flooding, declining stream flow and changes in riverside vegetation. The changing vegetation occurs because when trees cannot get adequate water they start to deteriorate, leading to a decreased food supply for the wildlife in an area.
Atmosphere, climate and weather | Natural environment | Wikipedia | 401 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
The atmosphere of the Earth serves as a key factor in sustaining the planetary ecosystem. The thin layer of gases that envelops the Earth is held in place by the planet's gravity. Dry air consists of 78% nitrogen, 21% oxygen, 1% argon, inert gases and carbon dioxide. The remaining gases are often referred to as trace gases. The atmosphere includes greenhouse gases such as carbon dioxide, methane, nitrous oxide and ozone. Filtered air includes trace amounts of many other chemical compounds. Air also contains a variable amount of water vapor and suspensions of water droplets and ice crystals seen as clouds. Many natural substances may be present in tiny amounts in an unfiltered air sample, including dust, pollen and spores, sea spray, volcanic ash and meteoroids. Various industrial pollutants also may be present, such as chlorine (elementary or in compounds), fluorine compounds, elemental mercury, and sulphur compounds such as sulphur dioxide (SO2).
The ozone layer of the Earth's atmosphere plays an important role in reducing the amount of ultraviolet (UV) radiation that reaches the surface. As DNA is readily damaged by UV light, this serves to protect life at the surface. The atmosphere also retains heat during the night, thereby reducing the daily temperature extremes.
Layers of the atmosphere | Natural environment | Wikipedia | 271 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Principal layers
Earth's atmosphere can be divided into five main layers. These layers are mainly determined by whether temperature increases or decreases with altitude. From highest to lowest, these layers are:
Exosphere: The outermost layer of Earth's atmosphere extends from the exobase upward, mainly composed of hydrogen and helium.
Thermosphere: The top of the thermosphere is the bottom of the exosphere, called the exobase. Its height varies with solar activity and ranges from about . The International Space Station orbits in this layer, between . In another way, the thermosphere is Earth's second highest atmospheric layer, extending from approximately 260,000 feet at the mesopause to the thermopause at altitudes ranging from 1,600,000 to 3,300,000 feet.
Mesosphere: The mesosphere extends from the stratopause to . It is the layer where most meteors burn up upon entering the atmosphere.
Stratosphere: The stratosphere extends from the tropopause to about . The stratopause, which is the boundary between the stratosphere and mesosphere, typically is at .
Troposphere: The troposphere begins at the surface and extends to between at the poles and at the equator, with some variation due to weather. The troposphere is mostly heated by transfer of energy from the surface, so on average the lowest part of the troposphere is warmest and temperature decreases with altitude. The tropopause is the boundary between the troposphere and stratosphere. | Natural environment | Wikipedia | 325 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Other layers
Within the five principal layers determined by temperature there are several layers determined by other properties.
The ozone layer is contained within the stratosphere. It is mainly located in the lower portion of the stratosphere from about , though the thickness varies seasonally and geographically. About 90% of the ozone in our atmosphere is contained in the stratosphere.
The ionosphere: The part of the atmosphere that is ionized by solar radiation, stretches from and typically overlaps both the exosphere and the thermosphere. It forms the inner edge of the magnetosphere.
The homosphere and heterosphere: The homosphere includes the troposphere, stratosphere and mesosphere. The upper part of the heterosphere is composed almost completely of hydrogen, the lightest element.
The planetary boundary layer is the part of the troposphere that is nearest the Earth's surface and is directly affected by it, mainly through turbulent diffusion.
Effects of global warming
The dangers of global warming are being increasingly studied by a wide global consortium of scientists. These scientists are increasingly concerned about the potential long-term effects of global warming on our natural environment and on the planet. Of particular concern is how climate change and global warming caused by anthropogenic, or human-made releases of greenhouse gases, most notably carbon dioxide, can act interactively and have adverse effects upon the planet, its natural environment and humans' existence. It is clear the planet is warming, and warming rapidly. This is due to the greenhouse effect, which is caused by greenhouse gases, which trap heat inside the Earth's atmosphere because of their more complex molecular structure which allows them to vibrate and in turn trap heat and release it back towards the Earth. This warming is also responsible for the extinction of natural habitats, which in turn leads to a reduction in wildlife population. The most recent report from the Intergovernmental Panel on Climate Change (the group of the leading climate scientists in the world) concluded that the earth will warm anywhere from 2.7 to almost 11 degrees Fahrenheit (1.5 to 6 degrees Celsius) between 1990 and 2100.
Efforts have been increasingly focused on the mitigation of greenhouse gases that are causing climatic changes, on developing adaptative strategies to global warming, to assist humans, other animal, and plant species, ecosystems, regions and nations in adjusting to the effects of global warming. Some examples of recent collaboration to address climate change and global warming include: | Natural environment | Wikipedia | 505 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
The United Nations Framework Convention Treaty and convention on Climate Change, to stabilize greenhouse gas concentrations in the atmosphere at a level that would prevent dangerous anthropogenic interference with the climate system.
The Kyoto Protocol, which is the protocol to the international Framework Convention on Climate Change treaty, again with the objective of reducing greenhouse gases in an effort to prevent anthropogenic climate change.
The Western Climate Initiative, to identify, evaluate, and implement collective and cooperative ways to reduce greenhouse gases in the region, focusing on a market-based cap-and-trade system.
A significantly profound challenge is to identify the natural environmental dynamics in contrast to environmental changes not within natural variances. A common solution is to adapt a static view neglecting natural variances to exist. Methodologically, this view could be defended when looking at processes which change slowly and short time series, while the problem arrives when fast processes turns essential in the object of the study.
Climate
Climate looks at the statistics of temperature, humidity, atmospheric pressure, wind, rainfall, atmospheric particle count and other meteorological elements in a given region over long periods of time. Weather, on the other hand, is the present condition of these same elements over periods up to two weeks.
Climates can be classified according to the average and typical ranges of different variables, most commonly temperature and precipitation. The most commonly used classification scheme is the one originally developed by Wladimir Köppen. The Thornthwaite system, in use since 1948, uses evapotranspiration as well as temperature and precipitation information to study animal species diversity and the potential impacts of climate changes.
Weather
Weather is a set of all the phenomena occurring in a given atmospheric area at a given time. Most weather phenomena occur in the troposphere, just below the stratosphere. Weather refers, generally, to day-to-day temperature and precipitation activity, whereas climate is the term for the average atmospheric conditions over longer periods of time. When used without qualification, "weather" is understood to be the weather of Earth. | Natural environment | Wikipedia | 408 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Weather occurs due to density (temperature and moisture) differences between one place and another. These differences can occur due to the sun angle at any particular spot, which varies by latitude from the tropics. The strong temperature contrast between polar and tropical air gives rise to the jet stream. Weather systems in the mid-latitudes, such as extratropical cyclones, are caused by instabilities of the jet stream flow. Because the Earth's axis is tilted relative to its orbital plane, sunlight is incident at different angles at different times of the year. On the Earth's surface, temperatures usually range ±40 °C (100 °F to −40 °F) annually. Over thousands of years, changes in the Earth's orbit have affected the amount and distribution of solar energy received by the Earth and influenced long-term climate.
Surface temperature differences in turn cause pressure differences. Higher altitudes are cooler than lower altitudes due to differences in compressional heating. Weather forecasting is the application of science and technology to predict the state of the atmosphere for a future time and a given location. The atmosphere is a chaotic system, and small changes to one part of the system can grow to have large effects on the system as a whole. Human attempts to control the weather have occurred throughout human history, and there is evidence that civilized human activity such as agriculture and industry has inadvertently modified weather patterns.
Life
Evidence suggests that life on Earth has existed for about 3.7 billion years. All known life forms share fundamental molecular mechanisms, and based on these observations, theories on the origin of life attempt to find a mechanism explaining the formation of a primordial single cell organism from which all life originates. There are many different hypotheses regarding the path that might have been taken from simple organic molecules via pre-cellular life to protocells and metabolism.
Although there is no universal agreement on the definition of life, scientists generally accept that the biological manifestation of life is characterized by organization, metabolism, growth, adaptation, response to stimuli and reproduction. Life may also be said to be simply the characteristic state of organisms. In biology, the science of living organisms, "life" is the condition which distinguishes active organisms from inorganic matter, including the capacity for growth, functional activity and the continual change preceding death. | Natural environment | Wikipedia | 458 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
A diverse variety of living organisms (life forms) can be found in the biosphere on Earth, and properties common to these organisms—plants, animals, fungi, protists, archaea, and bacteria—are a carbon- and water-based cellular form with complex organization and heritable genetic information. Living organisms undergo metabolism, maintain homeostasis, possess a capacity to grow, respond to stimuli, reproduce and, through natural selection, adapt to their environment in successive generations. More complex living organisms can communicate through various means.
Ecosystems
An ecosystem (also called an environment) is a natural unit consisting of all plants, animals, and micro-organisms (biotic factors) in an area functioning together with all of the non-living physical (abiotic) factors of the environment.
Central to the ecosystem concept is the idea that living organisms are continually engaged in a highly interrelated set of relationships with every other element constituting the environment in which they exist. Eugene Odum, one of the founders of the science of ecology, stated: "Any unit that includes all of the organisms (i.e.: the "community") in a given area interacting with the physical environment so that a flow of energy leads to clearly defined trophic structure, biotic diversity, and material cycles (i.e.: exchange of materials between living and nonliving parts) within the system is an ecosystem."
The human ecosystem concept is then grounded in the deconstruction of the human/nature dichotomy, and the emergent premise that all species are ecologically integrated with each other, as well as with the abiotic constituents of their biotope.
A more significant number or variety of species or biological diversity of an ecosystem may contribute to greater resilience of an ecosystem because there are more species present at a location to respond to change and thus "absorb" or reduce its effects. This reduces the effect before the ecosystem's structure changes to a different state. This is not universally the case and there is no proven relationship between the species diversity of an ecosystem and its ability to provide goods and services on a sustainable level.
The term ecosystem can also pertain to human-made environments, such as human ecosystems and human-influenced ecosystems. It can describe any situation where there is relationship between living organisms and their environment. Fewer areas on the surface of the earth today exist free from human contact, although some genuine wilderness areas continue to exist without any forms of human intervention. | Natural environment | Wikipedia | 507 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Biogeochemical cycles
Global biogeochemical cycles are critical to life, most notably those of water, oxygen, carbon, nitrogen and phosphorus.
The nitrogen cycle is the transformation of nitrogen and nitrogen-containing compounds in nature. It is a cycle which includes gaseous components.
The water cycle, is the continuous movement of water on, above, and below the surface of the Earth. Water can change states among liquid, vapour, and ice at various places in the water cycle. Although the balance of water on Earth remains fairly constant over time, individual water molecules can come and go.
The carbon cycle is the biogeochemical cycle by which carbon is exchanged among the biosphere, pedosphere, geosphere, hydrosphere, and atmosphere of the Earth.
The oxygen cycle is the movement of oxygen within and between its three main reservoirs: the atmosphere, the biosphere, and the lithosphere. The main driving factor of the oxygen cycle is photosynthesis, which is responsible for the modern Earth's atmospheric composition and life.
The phosphorus cycle is the movement of phosphorus through the lithosphere, hydrosphere, and biosphere. The atmosphere does not play a significant role in the movements of phosphorus, because phosphorus and phosphorus compounds are usually solids at the typical ranges of temperature and pressure found on Earth.
Wilderness
Wilderness is generally defined as a natural environment on Earth that has not been significantly modified by human activity. The WILD Foundation goes into more detail, defining wilderness as: "The most intact, undisturbed wild natural areas left on our planet – those last truly wild places that humans do not control and have not developed with roads, pipelines or other industrial infrastructure." Wilderness areas and protected parks are considered important for the survival of certain species, ecological studies, conservation, solitude, and recreation. Wilderness is deeply valued for cultural, spiritual, moral, and aesthetic reasons. Some nature writers believe wilderness areas are vital for the human spirit and creativity. | Natural environment | Wikipedia | 401 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
The word, "wilderness", derives from the notion of wildness; in other words that which is not controllable by humans. The word etymology is from the Old English wildeornes, which in turn derives from wildeor meaning wild beast (wild + deor = beast, deer). From this point of view, it is the wildness of a place that makes it a wilderness. The mere presence or activity of people does not disqualify an area from being "wilderness". Many ecosystems that are, or have been, inhabited or influenced by activities of people may still be considered "wild". This way of looking at wilderness includes areas within which natural processes operate without very noticeable human interference.
Wildlife includes all non-domesticated plants, animals and other organisms. Domesticating wild plant and animal species for human benefit has occurred many times all over the planet, and has a major impact on the environment, both positive and negative. Wildlife can be found in all ecosystems. Deserts, rain forests, plains, and other areas—including the most developed urban sites—all have distinct forms of wildlife. While the term in popular culture usually refers to animals that are untouched by civilized human factors, most scientists agree that wildlife around the world is (now) impacted by human activities.
Challenges
It is the common understanding of natural environment that underlies environmentalism — a broad political, social and philosophical movement that advocates various actions and policies in the interest of protecting what nature remains in the natural environment, or restoring or expanding the role of nature in this environment. While true wilderness is increasingly rare, wild nature (e.g., unmanaged forests, uncultivated grasslands, wildlife, wildflowers) can be found in many locations previously inhabited by humans. | Natural environment | Wikipedia | 357 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Goals for the benefit of people and natural systems, commonly expressed by environmental scientists and environmentalists include:
Elimination of pollution and toxicants in air, water, soil, buildings, manufactured goods, and food.
Preservation of biodiversity and protection of endangered species.
Conservation and sustainable use of resources such as water, land, air, energy, raw materials, and natural resources.
Halting human-induced global warming, which represents pollution, a threat to biodiversity, and a threat to human populations.
Shifting from fossil fuels to renewable energy in electricity, heating and cooling, and transportation, which addresses pollution, global warming, and sustainability. This may include public transportation and distributed generation, which have benefits for traffic congestion and electric reliability.
Shifting from meat-intensive diets to largely plant-based diets in order to help mitigate biodiversity loss and climate change.
Establishment of nature reserves for recreational purposes and ecosystem preservation.
Sustainable and less polluting waste management including waste reduction (or even zero waste), reuse, recycling, composting, waste-to-energy, and anaerobic digestion of sewage sludge.
Reducing profligate consumption and clamping down on illegal fishing and logging.
Slowing and stabilisation of human population growth.
Reducing the import of second hand electronic appliances from developed countries to developing countries.
Criticism
In some cultures the term environment is meaningless because there is no separation between people and what they view as the natural world, or their surroundings. Specifically in the United States and Arabian countries many native cultures do not recognize the "environment", or see themselves as environmentalists. | Natural environment | Wikipedia | 319 | 558685 | https://en.wikipedia.org/wiki/Natural%20environment | Physical sciences | Earth science basics: General | Earth science |
Lactococcus lactis is a gram-positive bacterium used extensively in the production of buttermilk and cheese, but has also become famous as the first genetically modified organism to be used alive for the treatment of human disease. L. lactis cells are cocci that group in pairs and short chains, and, depending on growth conditions, appear ovoid with a typical length of 0.5 - 1.5 μm. L. lactis does not produce spores (nonsporulating) and are not motile (nonmotile). They have a homofermentative metabolism, meaning they produce lactic acid from sugars. They've also been reported to produce exclusive L-(+)-lactic acid. However, reported D-(−)-lactic acid can be produced when cultured at low pH. The capability to produce lactic acid is one of the reasons why L. lactis is one of the most important microorganisms in the dairy industry. Based on its history in food fermentation, L. lactis has generally recognized as safe (GRAS) status, with few case reports of it being an opportunistic pathogen.
Lactococcus lactis is of crucial importance for manufacturing dairy products, such as buttermilk and cheeses. When L. lactis ssp. lactis is added to milk, the bacterium uses enzymes to produce energy molecules (ATP), from lactose. The byproduct of ATP energy production is lactic acid. The lactic acid produced by the bacterium curdles the milk, which then separates to form curds that are used to produce cheese. Other uses that have been reported for this bacterium include the production of pickled vegetables, beer or wine, some breads, and other fermented foodstuffs like soymilk kefir, buttermilk, and others. L. lactis is one of the best characterized low GC Gram positive bacteria with detailed knowledge on genetics, metabolism and biodiversity. | Lactococcus lactis | Wikipedia | 415 | 559011 | https://en.wikipedia.org/wiki/Lactococcus%20lactis | Biology and health sciences | Gram-positive bacteria | Plants |
L. lactis is mainly isolated from either the dairy environment, or plant material. Dairy isolates are suggested to have evolved from plant isolates through a process in which genes without benefit in the rich milk were lost or downregulated. This process, called genome erosion or reductive evolution, has been described in several other lactic acid bacteria. The proposed transition from the plant to the dairy environment was reproduced in the laboratory through experimental evolution of a plant isolate that was cultivated in milk for a prolonged period. Consistent with the results from comparative genomics (see references above), this resulted in L. lactis losing or downregulating genes that are dispensable in milk and the upregulation of peptide transport.
Hundreds of novel small RNAs were identified by Meulen et al. in the genome of L. lactis MG1363. One of them, LLnc147, was shown to be involved in carbon uptake and metabolism.
Cheese production
L. lactis subsp. lactis (formerly Streptococcus lactis) is used in the early stages for the production of many cheeses, including brie, camembert, Cheddar, Colby, Gruyère, Parmesan, and Roquefort. The use of L. lactis in dairy factories is not without issues. Bacteriophages specific to L. lactis cause significant economic losses each year by preventing the bacteria from fully metabolizing the milk substrate. Several epidemiologic studies showed the phages mainly responsible for these losses are from the species 936, c2, and P335 (all from the family Siphoviridae).
The state Assembly of Wisconsin, also the number one cheese-producing state in the United States, voted in 2010 to name this bacterium as the official state microbe; it would have been the first and only such designation by a state legislature in the nation, however the legislation was not adopted by the Senate. The legislation was introduced in November 2009 as Assembly Bill 556 by Representatives Hebl, Vruwink, Williams, Pasch, Danou, and Fields; it was cosponsored by Senator Taylor. The bill passed the Assembly on May 15, 2010, and was dropped by the Senate on April 28. | Lactococcus lactis | Wikipedia | 469 | 559011 | https://en.wikipedia.org/wiki/Lactococcus%20lactis | Biology and health sciences | Gram-positive bacteria | Plants |
Therapeutic benefits
The feasibility of using lactic acid bacteria (LAB) as functional protein delivery vectors has been widely investigated. Lactococcus lactis has been demonstrated to be a promising candidate for the delivery of functional proteins because of its noninvasive and nonpathogenic characteristics. Many different expression systems of L. lactis have been developed and used for heterologous protein expression.
Lactose fermentation
In one study that sought to prove that some fermentation produced by L. lactis can hinder motility in pathogenic bacteria, the motilities of Pseudomonas, Vibrio, and Leptospira strains were severely disrupted by lactose utilization on the part of L. lactis. Using flagellar Salmonella as the experimental group, the research team found that a product of lactose fermentation is the cause of motility impairment in Salmonella. It is suggested that the L. lactis supernatant mainly affects Salmonella motility through disruption of flagellar rotation rather than through irreversible damage to morphology and physiology. Lactose fermentation by L. lactis produces acetate that reduces the intracellular pH of Salmonella, which in turn slows the rotation of their flagella. These results highlight the potential use of L. lactis for preventing infections by multiple bacterial species.
Secretion of Interleukin-10
Genetically engineered L. lactis can secrete the cytokine interleukin-10 (IL-10) for the treatment of inflammatory bowel diseases (IBD), since IL-10 has a central role in downregulating inflammatory cascades and matrix metalloproteinases. A study by Lothar Steidler and Wolfgang Hans shows that in situ synthesis of IL-10 by genetically engineered L. lactis requires much lower doses than systemic treatments like antibodies to tumor necrosis factor (TNF) or recombinant IL-10. | Lactococcus lactis | Wikipedia | 400 | 559011 | https://en.wikipedia.org/wiki/Lactococcus%20lactis | Biology and health sciences | Gram-positive bacteria | Plants |
The authors propose two possible routes by which IL-10 can reach its therapeutic target. Genetically engineered L. lactis may produce murine IL-10 in the lumen, and the protein may diffuse to responsive cells in the epithelium or the lamina propria. Another route involves L. lactis being taken up by M cells because of its bacterial size and shape, and the major part of the effect may be due to recombinant IL-10 production in situ in intestinal lymphoid tissue. Both routes may involve paracellular transport mechanisms that are enhanced in inflammation. After transport, IL-10 may directly downregulate inflammation. In principle, this method may be useful for intestinal delivery of other protein therapeutics that are unstable or difficult to produce in large quantities and an alternative to the systemic treatment of IBD.
Tumor-suppressor through Tumor metastasis-inhibiting peptide KISS1
Another study, led by Zhang B, created a L. lactis strain that maintains a plasmid containing a tumor metastasis-inhibiting peptide known as KISS1. L. lactis NZ9000 was demonstrated to be a cell factory for the secretion of biologically active KiSS1 protein, exerting inhibition effects on human colorectal cancer HT-29 cells.
KiSS1 secreted from recombinant L. lactis strain effectively downregulated the expression of Matrix metalloproteinases (MMP-9), a crucial key in the invasion, metastasis, and regulation of the signaling pathways controlling tumor cell growth, survival, invasion, inflammation, and angiogenesis. The reason for this is that KiSS1 expressed in L. lactis activates the MAPK pathway via GPR54 signaling, suppressing NFκB binding to the MMP-9 promoter and thus downregulating MMP-9 expression. This, in turn, reduces the survival rate, inhibits metastasis, and induces dormancy of cancer cells. | Lactococcus lactis | Wikipedia | 414 | 559011 | https://en.wikipedia.org/wiki/Lactococcus%20lactis | Biology and health sciences | Gram-positive bacteria | Plants |
In addition, it was demonstrated that tumor growth can be inhibited by the LAB strain itself, due to the ability of LAB to produce exopolysaccharides. This study shows that L. lactis NZ9000 can inhibit HT-29 proliferation and induce cell apoptosis by itself. The success of this strain's construction helped to inhibit migration and expansion of cancer cells, showing that the secretion properties of L. lactis of this particular peptide may serve as a new tool for cancer therapy in the future. | Lactococcus lactis | Wikipedia | 109 | 559011 | https://en.wikipedia.org/wiki/Lactococcus%20lactis | Biology and health sciences | Gram-positive bacteria | Plants |
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal, and Robertsonian translocation. Reciprocal translocation is a chromosome abnormality caused by exchange of parts between non-homologous chromosomes. Two detached fragments of two different chromosomes are switched. Robertsonian translocation occurs when two non-homologous chromosomes get attached, meaning that given two healthy pairs of chromosomes, one of each pair "sticks" and blends together homogeneously.
A gene fusion may be created when the translocation joins two otherwise-separated genes. It is detected on cytogenetics or a karyotype of affected cells. Translocations can be balanced (in an even exchange of material with no genetic information extra or missing, and ideally full functionality) or unbalanced (where the exchange of chromosome material is unequal resulting in extra or missing genes).
Reciprocal translocations
Reciprocal translocations are usually an exchange of material between non-homologous chromosomes and occur in about 1 in 491 live births. Such translocations are usually harmless, as they do not result in a gain or loss of genetic material, though they may be detected in prenatal diagnosis. However, carriers of balanced reciprocal translocations may create gametes with unbalanced chromosome translocations during meiotic chromosomal segregation. This can lead to infertility, miscarriages or children with abnormalities. Genetic counseling and genetic testing are often offered to families that may carry a translocation. Most balanced translocation carriers are healthy and do not have any symptoms.
It is important to distinguish between chromosomal translocations that occur in germ cells, due to errors in meiosis (i.e. during gametogenesis), and those that occur in somatic cells, due to errors in mitosis. The former results in a chromosomal abnormality featured in all cells of the offspring, as in translocation carriers. Somatic translocations, on the other hand, result in abnormalities featured only in the affected cell and its progenitors, as in chronic myelogenous leukemia with the Philadelphia chromosome translocation.
Nonreciprocal translocation
Nonreciprocal translocation involves the one-way transfer of genes from one chromosome to another nonhomologous chromosome. | Chromosomal translocation | Wikipedia | 507 | 560502 | https://en.wikipedia.org/wiki/Chromosomal%20translocation | Biology and health sciences | Genetics | Biology |
Robertsonian translocations
Robertsonian translocation is a type of translocation caused by breaks at or near the centromeres of two acrocentric chromosomes. The reciprocal exchange of parts gives rise to one large metacentric chromosome and one extremely small chromosome that may be lost from the organism with little effect because it contains few genes. The resulting karyotype in humans leaves only 45 chromosomes, since two chromosomes have fused together. This has no direct effect on the phenotype, since the only genes on the short arms of acrocentrics are common to all of them and are present in variable copy number (nucleolar organiser genes).
Robertsonian translocations have been seen involving all combinations of acrocentric chromosomes. The most common translocation in humans involves chromosomes 13 and 14 and is seen in about 0.97 / 1000 newborns. Carriers of Robertsonian translocations are not associated with any phenotypic abnormalities, but there is a risk of unbalanced gametes that lead to miscarriages or abnormal offspring. For example, carriers of Robertsonian translocations involving chromosome 21 have a higher risk of having a child with Down syndrome. This is known as a 'translocation Downs'. This is due to a mis-segregation (nondisjunction) during gametogenesis. The mother has a higher (10%) risk of transmission than the father (1%). Robertsonian translocations involving chromosome 14 also carry a slight risk of uniparental disomy 14 due to trisomy rescue.
Role in disease
Some human diseases caused by translocations are:
Cancer: Several forms of cancer are caused by acquired translocations (as opposed to those present from conception); this has been described mainly in leukemia (acute myelogenous leukemia and chronic myelogenous leukemia). Translocations have also been described in solid malignancies such as Ewing's sarcoma.
Infertility: One of the would-be parents carries a balanced translocation, where the parent is asymptomatic but conceived fetuses are not viable.
Down syndrome is caused in a minority (5% or less) of cases by a Robertsonian translocation of the chromosome 21 long arm onto the long arm of chromosome 14. | Chromosomal translocation | Wikipedia | 479 | 560502 | https://en.wikipedia.org/wiki/Chromosomal%20translocation | Biology and health sciences | Genetics | Biology |
Chromosomal translocations between the sex chromosomes can also result in a number of genetic conditions, such as
XX male syndrome: caused by a translocation of the SRY gene from the Y to the X chromosome
By chromosome
Denotation
The International System for Human Cytogenetic Nomenclature (ISCN) is used to denote a translocation between chromosomes. The designation t(A;B)(p1;q2) is used to denote a translocation between chromosome A and chromosome B. The information in the second set of parentheses, when given, gives the precise location within the chromosome for chromosomes A and B respectively—with p indicating the short arm of the chromosome, q indicating the long arm, and the numbers after p or q refers to regions, bands and sub-bands seen when staining the chromosome with a staining dye. | Chromosomal translocation | Wikipedia | 176 | 560502 | https://en.wikipedia.org/wiki/Chromosomal%20translocation | Biology and health sciences | Genetics | Biology |
Umber is a natural earth pigment consisting of iron oxide and manganese oxide; it has a brownish color that can vary among shades of yellow, red, and green. Umber is considered one of the oldest pigments known to humans, first seen in Ajanta Caves in 200 BC – 600 AD. Umber's advantages are its highly versatile color, warm tone, and quick drying abilities. While some sources indicate that umber's name comes from its geographic origin in Umbria, other scholars suggest that it derives from the Latin word umbra, which means "shadow". The belief that its name derives from the word for shadow is fitting, as the color helps create shadows. The color is primarily produced in Cyprus. Umber is typically mined from open pits or underground mines and ground into a fine powder that is washed to remove impurities. In the 20th century, the rise of synthetic dyes decreased the demand for natural pigments such as umber.
History
The earliest documented uses of umber date from between 200 BC and 600 AD in the Ajanta Caves found in India. Ocher, a family of earth pigments which includes umber, has been identified in the caves of Altamira in Spain and the Lascaux Cave in France. Some sources indicate that umber was not frequently used in medieval art because of its emphasis on bright and vivid colors. Other sources indicate, however, that umber was used in the Middle Ages to create different shades of brown, most often seen for skin tones. Umber's use in Europe increased in the late 15th century. Umber became more popular during the Renaissance when its versatility, earthy appearance, availability, and inexpensiveness were recognized.
Umber gained widespread popularity in Dutch landscape painting in the eighteenth century. Artists recognized the value of umber's high stability, inertness, and drying abilities. It became a standard color within eighteenth-century palettes throughout Europe. Umber's popularity grew during the Baroque period with the rise of the chiaroscuro style. Umber allowed painters to create an intense light and dark contrast. Underpainting was another popular technique for painting that used umber as a base color. Umber was valuable in deploying this technique, creating a range of earth like tones with various layering of color. | Umber | Wikipedia | 471 | 561853 | https://en.wikipedia.org/wiki/Umber | Physical sciences | Minerals | Earth science |
Toward the end of the 19th century, the Impressionist movement started to use cheaper and more readily available synthetic dyes and reject natural pigments like umber to create mixed hues of brown. The Impressionists chose to make their own browns from mixtures of red, yellow, green, blue and other pigments, particularly the new synthetic pigments such as cobalt blue and emerald green that had just been introduced. In the 20th century, natural umber pigments began to be replaced by pigments made with synthetic iron oxide and manganese oxide.
Criticism
Beginning in the 17th century, umber was increasingly criticized within the art community. British painter Edward Norgate, prominent with British royalty and aristocracy, called umber "a foul and greasy color." In the 18th century, Spanish painter Antonio Palomino called umber "very false." Jan Blockx, a Belgian painter, opined, "umber should not appear on the palette of the conscientious painter."
Visual properties
Umber is a natural brown pigment extracted from clay containing iron, manganese, and hydroxides. Umber has diverse hues, ranging from yellow-brown to reddish-brown and even green-brown. The color shade varies depending on the proportions of the components. When heated, umber becomes a more intense color and can look almost black. Burnt umber is produced by calcining the raw version. The raw form of umber is typically used for ceramics because it is less expensive.
These warm and earthy tones make it a valuable and versatile pigment for oil painting and other artwork. Umber's high opacity and reactivity of light allow the pigment to have strong hiding power. It is insoluble in water, resistant to alkalis and weak acids, and non-reactive with cement, solvents, oils, and most resins. Umber is known for its stability.
Notable occurrences
Umber became widely used throughout the Renaissance period for oil paintings. In the Mona Lisa, Leonardo da Vinci used umber for the brown tones throughout his subject’s hair and clothing. Da Vinci also extensively used umber in his painting the Last Supper to create shadows and outlines of the figures. Throughout the Baroque period, many renowned painters used umber.
Varieties
Raw umber
This is the color raw umber.
Burnt umber | Umber | Wikipedia | 474 | 561853 | https://en.wikipedia.org/wiki/Umber | Physical sciences | Minerals | Earth science |
Burnt umber is made by heating raw umber, which dehydrates the iron oxides and changes them partially to the more reddish hematite. It is used for both oil and water color paint.
The first recorded use of burnt umber as a color name in English was in 1650. | Umber | Wikipedia | 61 | 561853 | https://en.wikipedia.org/wiki/Umber | Physical sciences | Minerals | Earth science |
Earth pigments are naturally occurring minerals that have been used since prehistoric times as pigments. Among the primary types of earth pigments include the reddish-brown ochres, siennas, and umbers, which contain various amounts of iron oxides and manganese oxides. Other earth pigments include the green earth pigments or , blue earth pigments such as vivianite-based "blue ochre", white earth pigments such as chalk, and black earth pigments such as charcoal.
Earth pigments are known for their fast drying time in oil painting, relative inexpensiveness, and lightfastness. Cave paintings done in sienna still survive today.
Production
After mining, the mineral used for making a pigment is ground to a very fine powder (if not already in the form of clay), washed to remove water-soluble components, dried, and ground again to powder. For some pigments, notably sienna and umber, the color can be deepened by heating (calcination) in a process known as "burning", although it does not involve oxidation but instead dehydration. | Earth pigment | Wikipedia | 222 | 561873 | https://en.wikipedia.org/wiki/Earth%20pigment | Physical sciences | Minerals | Earth science |
Magnesium chloride is an inorganic compound with the formula . It forms hydrates , where n can range from 1 to 12. These salts are colorless or white solids that are highly soluble in water. These compounds and their solutions, both of which occur in nature, have a variety of practical uses. Anhydrous magnesium chloride is the principal precursor to magnesium metal, which is produced on a large scale. Hydrated magnesium chloride is the form most readily available.
Production
Magnesium chloride can be extracted from brine or sea water. In North America and South America too, it is produced primarily from Great Salt Lake brine. In the Jordan Valley, it is obtained from the Dead Sea. The mineral bischofite () is extracted (by solution mining) out of ancient seabeds, for example, the Zechstein seabed in northwest Europe. Some deposits result from high content of magnesium chloride in the primordial ocean. Some magnesium chloride is made from evaporation of seawater.
In the Dow process, magnesium chloride is regenerated from magnesium hydroxide using hydrochloric acid:
It can also be prepared from magnesium carbonate by a similar reaction.
Structure
crystallizes in the cadmium chloride motif, therefore it loses water upon heating: n = 12 (−16.4 °C), 8 (−3.4 °C), 6 (116.7 °C), 4 (181 °C), 2 (about 300 °C). In the hexahydrate, the is also octahedral, being coordinated to six water ligands. The octahydrate and the dodecahydrate can be crystallized from water below 298K. As verified by X-ray crystallography, these "higher" hydrates also feature [Mg(H2O)6]2+ ions. A decahydrate has also been crystallized.
Preparation, general properties
Anhydrous is produced industrially by heating the complex salt named hexamminemagnesium dichloride . The thermal dehydration of the hydrates (n = 6, 12) does not occur straightforwardly. | Magnesium chloride | Wikipedia | 437 | 562007 | https://en.wikipedia.org/wiki/Magnesium%20chloride | Physical sciences | Halide salts | Chemistry |
As suggested by the existence of hydrates, anhydrous is a Lewis acid, although a weak one. One derivative is tetraethylammonium tetrachloromagnesate . The adduct is another. In the coordination polymer with the formula , Mg adopts an octahedral geometry. The Lewis acidity of magnesium chloride is reflected in its deliquescence, meaning that it attracts moisture from the air to the extent that the solid turns into a liquid.
Applications
Precursor to metallic magnesium
Anhydrous is the main precursor to metallic magnesium. The reduction of into metallic Mg is performed by electrolysis in molten salt. As it is also the case for aluminium, an electrolysis in aqueous solution is not possible as the produced metallic magnesium would immediately react with water, or in other words that the water would be reduced into gaseous before Mg reduction could occur. So, the direct electrolysis of molten in the absence of water is required because the reduction potential to obtain Mg is lower than the stability domain of water on an Eh–pH diagram (Pourbaix diagram).
The production of metallic magnesium at the cathode (reduction reaction) is accompanied by the oxidation of the chloride anions at the anode with release of gaseous chlorine. This process is developed at a large industrial scale.
Dust and erosion control
Magnesium chloride is one of many substances used for dust control, soil stabilization, and wind erosion mitigation. When magnesium chloride is applied to roads and bare soil areas, both positive and negative performance issues occur which are related to many application factors.
Catalysis
Ziegler-Natta catalysts, used commercially to produce polyolefins, often contain as a catalyst support. The introduction of supports increases the activity of traditional catalysts and allowed the development of highly stereospecific catalysts for the production of polypropylene.
Magnesium chloride is also a Lewis acid catalyst in aldol reactions.
Ice control
Magnesium chloride is used for low-temperature de-icing of highways, sidewalks, and parking lots. When highways are treacherous due to icy conditions, magnesium chloride is applied to help prevent ice from bonding to the pavement, allowing snow plows to clear treated roads more efficiently. | Magnesium chloride | Wikipedia | 455 | 562007 | https://en.wikipedia.org/wiki/Magnesium%20chloride | Physical sciences | Halide salts | Chemistry |
For the purpose of preventing ice from forming on pavement, magnesium chloride is applied in three ways: anti-icing, which involves spreading it on roads to prevent snow from sticking and forming; prewetting, which means a liquid formulation of magnesium chloride is sprayed directly onto salt as it is being spread onto roadway pavement, wetting the salt so that it sticks to the road; and pretreating, when magnesium chloride and salt are mixed together before they are loaded onto trucks and spread onto paved roads. Calcium chloride damages concrete twice as fast as magnesium chloride. The amount of magnesium chloride is supposed to be controlled when it is used for de-icing as it may cause pollution to the environment.
Nutrition and medicine
Magnesium chloride is used in nutraceutical and pharmaceutical preparations. The hexahydrate is sometimes advertised as "magnesium oil".
Cuisine
Magnesium chloride (E511) is an important coagulant used in the preparation of tofu from soy milk.
In Japan it is sold as nigari (にがり, derived from the Japanese word for "bitter"), a white powder produced from seawater after the sodium chloride has been removed, and the water evaporated. In China, it is called lushui (卤水).
Nigari or Iushui is, in fact, natural magnesium chloride, meaning that it is not completely refined (it contains up to 5% magnesium sulfate and various minerals). The crystals originate from lakes in the Chinese province of Qinghai, to be then reworked in Japan.
Gardening and horticulture
Because magnesium is a mobile nutrient, magnesium chloride can be effectively used as a substitute for magnesium sulfate (Epsom salt) to help correct magnesium deficiency in plants via foliar feeding. The recommended dose of magnesium chloride is smaller than the recommended dose of magnesium sulfate (20 g/L). This is due primarily to the chlorine present in magnesium chloride, which can easily reach toxic levels if over-applied or applied too often.
It has been found that higher concentrations of magnesium in tomato and some pepper plants can make them more susceptible to disease caused by infection of the bacterium Xanthomonas campestris, since magnesium is essential for bacterial growth.
Wastewater treatment
It is used to supply the magnesium necessary to precipitate phosphorus in the form of struvite from agricultural waste as well as human urine.
Occurrence | Magnesium chloride | Wikipedia | 484 | 562007 | https://en.wikipedia.org/wiki/Magnesium%20chloride | Physical sciences | Halide salts | Chemistry |
Magnesium concentrations in natural seawater are between 1250 and 1350 mg/L, around 3.7% of the total seawater mineral content. Dead Sea minerals contain a significantly higher magnesium chloride ratio, 50.8%. Carbonates and calcium are essential for all growth of corals, coralline algae, clams, and invertebrates. Magnesium can be depleted by mangrove plants and the use of excessive limewater or by going beyond natural calcium, alkalinity, and pH values. The most common mineral form of magnesium chloride is its hexahydrate, bischofite. Anhydrous compound occurs very rarely, as chloromagnesite. Magnesium chloride-hydroxides, korshunovskite and nepskoeite, are also very rare.
Toxicology
Magnesium ions are bitter-tasting, and magnesium chloride solutions are bitter in varying degrees, depending on the concentration.
Magnesium toxicity from magnesium salts is rare in healthy individuals with a normal diet, because excess magnesium is readily excreted in urine by the kidneys. A few cases of oral magnesium toxicity have been described in persons with normal renal function ingesting large amounts of magnesium salts, but it is rare. If a large amount of magnesium chloride is eaten, it will have effects similar to magnesium sulfate, causing diarrhea, although the sulfate also contributes to the laxative effect in magnesium sulfate, so the effect from the chloride is not as severe.
Plant toxicity
Chloride () and magnesium () are both essential nutrients important for normal plant growth. Too much of either nutrient may harm a plant, although foliar chloride concentrations are more strongly related with foliar damage than magnesium. High concentrations of ions in the soil may be toxic or change water relationships such that the plant cannot easily accumulate water and nutrients. Once inside the plant, chloride moves through the water-conducting system and accumulates at the margins of leaves or needles, where dieback occurs first. Leaves are weakened or killed, which can lead to the death of the tree. | Magnesium chloride | Wikipedia | 412 | 562007 | https://en.wikipedia.org/wiki/Magnesium%20chloride | Physical sciences | Halide salts | Chemistry |
In mathematics and solid state physics, the first Brillouin zone (named after Léon Brillouin) is a uniquely defined primitive cell in reciprocal space. In the same way the Bravais lattice is divided up into Wigner–Seitz cells in the real lattice, the reciprocal lattice is broken up into Brillouin zones. The boundaries of this cell are given by planes related to points on the reciprocal lattice. The importance of the Brillouin zone stems from the description of waves in a periodic medium given by Bloch's theorem, in which it is found that the solutions can be completely characterized by their behavior in a single Brillouin zone.
The first Brillouin zone is the locus of points in reciprocal space that are closer to the origin of the reciprocal lattice than they are to any other reciprocal lattice points (see the derivation of the Wigner–Seitz cell). Another definition is as the set of points in k-space that can be reached from the origin without crossing any Bragg plane. Equivalently, this is the Voronoi cell around the origin of the reciprocal lattice.
There are also second, third, etc., Brillouin zones, corresponding to a sequence of disjoint regions (all with the same volume) at increasing distances from the origin, but these are used less frequently. As a result, the first Brillouin zone is often called simply the Brillouin zone. In general, the n-th Brillouin zone consists of the set of points that can be reached from the origin by crossing exactly n − 1 distinct Bragg planes. A related concept is that of the irreducible Brillouin zone, which is the first Brillouin zone reduced by all of the symmetries in the point group of the lattice (point group of the crystal).
The concept of a Brillouin zone was developed by Léon Brillouin (1889–1969), a French physicist.
Within the Brillouin zone, a constant-energy surface represents the loci of all the -points (that is, all the electron momentum values) that have the same energy. Fermi surface is a special constant-energy surface that separates the unfilled orbitals from the filled ones at zero kelvin.
Critical points
Several points of high symmetry are of special interest – these are called critical points.
Other lattices have different types of high-symmetry points. They can be found in the illustrations below. | Brillouin zone | Wikipedia | 496 | 562067 | https://en.wikipedia.org/wiki/Brillouin%20zone | Physical sciences | Crystallography | Physics |
A telescope is a device used to observe distant objects by their emission, absorption, or reflection of electromagnetic radiation. Originally, it was an optical instrument using lenses, curved mirrors, or a combination of both to observe distant objects – an optical telescope. Nowadays, the word "telescope" is defined as a wide range of instruments capable of detecting different regions of the electromagnetic spectrum, and in some cases other types of detectors.
The first known practical telescopes were refracting telescopes with glass lenses and were invented in the Netherlands at the beginning of the 17th century. They were used for both terrestrial applications and astronomy.
The reflecting telescope, which uses mirrors to collect and focus light, was invented within a few decades of the first refracting telescope.
In the 20th century, many new types of telescopes were invented, including radio telescopes in the 1930s and infrared telescopes in the 1960s.
Etymology
The word telescope was coined in 1611 by the Greek mathematician Giovanni Demisiani for one of Galileo Galilei's instruments presented at a banquet at the Accademia dei Lincei. In the Starry Messenger, Galileo had used the Latin term . The root of the word is from the Ancient Greek τῆλε, tele 'far' and σκοπεῖν, skopein 'to look or see'; τηλεσκόπος, teleskopos 'far-seeing'.
History
The earliest existing record of a telescope was a 1608 patent submitted to the government in the Netherlands by Middelburg spectacle maker Hans Lipperhey for a refracting telescope. The actual inventor is unknown but word of it spread through Europe. Galileo heard about it and, in 1609, built his own version, and made his telescopic observations of celestial objects.
The idea that the objective, or light-gathering element, could be a mirror instead of a lens was being investigated soon after the invention of the refracting telescope. The potential advantages of using parabolic mirrors—reduction of spherical aberration and no chromatic aberration—led to many proposed designs and several attempts to build reflecting telescopes. In 1668, Isaac Newton built the first practical reflecting telescope, of a design which now bears his name, the Newtonian reflector. | Telescope | Wikipedia | 459 | 7070301 | https://en.wikipedia.org/wiki/Telescope | Technology | Optical | null |
The invention of the achromatic lens in 1733 partially corrected color aberrations present in the simple lens and enabled the construction of shorter, more functional refracting telescopes. Reflecting telescopes, though not limited by the color problems seen in refractors, were hampered by the use of fast tarnishing speculum metal mirrors employed during the 18th and early 19th century—a problem alleviated by the introduction of silver coated glass mirrors in 1857, and aluminized mirrors in 1932. The maximum physical size limit for refracting telescopes is about , dictating that the vast majority of large optical researching telescopes built since the turn of the 20th century have been reflectors. The largest reflecting telescopes currently have objectives larger than , and work is underway on several 30–40m designs.
The 20th century also saw the development of telescopes that worked in a wide range of wavelengths from radio to gamma-rays. The first purpose-built radio telescope went into operation in 1937. Since then, a large variety of complex astronomical instruments have been developed.
In space
Since the atmosphere is opaque for most of the electromagnetic spectrum, only a few bands can be observed from the Earth's surface. These bands are visible – near-infrared and a portion of the radio-wave part of the spectrum. For this reason there are no X-ray or far-infrared ground-based telescopes as these have to be observed from orbit. Even if a wavelength is observable from the ground, it might still be advantageous to place a telescope on a satellite due to issues such as clouds, astronomical seeing and light pollution.
The disadvantages of launching a space telescope include cost, size, maintainability and upgradability.
Some examples of space telescopes from NASA are the Hubble Space Telescope that detects visible light, ultraviolet, and near-infrared wavelengths, the Spitzer Space Telescope that detects infrared radiation, and the Kepler Space Telescope that discovered thousands of exoplanets. The latest telescope that was launched was the James Webb Space Telescope on December 25, 2021, in Kourou, French Guiana. The Webb telescope detects infrared light.
By electromagnetic spectrum
The name "telescope" covers a wide range of instruments. Most detect electromagnetic radiation, but there are major differences in how astronomers must go about collecting light (electromagnetic radiation) in different frequency bands. | Telescope | Wikipedia | 471 | 7070301 | https://en.wikipedia.org/wiki/Telescope | Technology | Optical | null |
As wavelengths become longer, it becomes easier to use antenna technology to interact with electromagnetic radiation (although it is possible to make very tiny antenna). The near-infrared can be collected much like visible light; however, in the far-infrared and submillimetre range, telescopes can operate more like a radio telescope. For example, the James Clerk Maxwell Telescope observes from wavelengths from 3 μm (0.003 mm) to 2000 μm (2 mm), but uses a parabolic aluminum antenna. On the other hand, the Spitzer Space Telescope, observing from about 3 μm (0.003 mm) to 180 μm (0.18 mm) uses a mirror (reflecting optics). Also using reflecting optics, the Hubble Space Telescope with Wide Field Camera 3 can observe in the frequency range from about 0.2 μm (0.0002 mm) to 1.7 μm (0.0017 mm) (from ultra-violet to infrared light).
With photons of the shorter wavelengths, with the higher frequencies, glancing-incident optics, rather than fully reflecting optics are used. Telescopes such as TRACE and SOHO use special mirrors to reflect extreme ultraviolet, producing higher resolution and brighter images than are otherwise possible. A larger aperture does not just mean that more light is collected, it also enables a finer angular resolution.
Telescopes may also be classified by location: ground telescope, space telescope, or flying telescope. They may also be classified by whether they are operated by professional astronomers or amateur astronomers. A vehicle or permanent campus containing one or more telescopes or other instruments is called an observatory.
Radio and submillimeter
Radio telescopes are directional radio antennas that typically employ a large dish to collect radio waves. The dishes are sometimes constructed of a conductive wire mesh whose openings are smaller than the wavelength being observed.
Unlike an optical telescope, which produces a magnified image of the patch of sky being observed, a traditional radio telescope dish contains a single receiver and records a single time-varying signal characteristic of the observed region; this signal may be sampled at various frequencies. In some newer radio telescope designs, a single dish contains an array of several receivers; this is known as a focal-plane array. | Telescope | Wikipedia | 449 | 7070301 | https://en.wikipedia.org/wiki/Telescope | Technology | Optical | null |
By collecting and correlating signals simultaneously received by several dishes, high-resolution images can be computed. Such multi-dish arrays are known as astronomical interferometers and the technique is called aperture synthesis. The 'virtual' apertures of these arrays are similar in size to the distance between the telescopes. As of 2005, the record array size is many times the diameter of the Earth – using space-based very-long-baseline interferometry (VLBI) telescopes such as the Japanese HALCA (Highly Advanced Laboratory for Communications and Astronomy) VSOP (VLBI Space Observatory Program) satellite.
Aperture synthesis is now also being applied to optical telescopes using optical interferometers (arrays of optical telescopes) and aperture masking interferometry at single reflecting telescopes.
Radio telescopes are also used to collect microwave radiation, which has the advantage of being able to pass through the atmosphere and interstellar gas and dust clouds.
Some radio telescopes such as the Allen Telescope Array are used by programs such as SETI and the Arecibo Observatory to search for extraterrestrial life.
Infrared
Visible light
An optical telescope gathers and focuses light mainly from the visible part of the electromagnetic spectrum. Optical telescopes increase the apparent angular size of distant objects as well as their apparent brightness. For the image to be observed, photographed, studied, and sent to a computer, telescopes work by employing one or more curved optical elements, usually made from glass lenses and/or mirrors, to gather light and other electromagnetic radiation to bring that light or radiation to a focal point. Optical telescopes are used for astronomy and in many non-astronomical instruments, including: theodolites (including transits), spotting scopes, monoculars, binoculars, camera lenses, and spyglasses. There are three main optical types:
The refracting telescope which uses lenses to form an image.
The reflecting telescope which uses an arrangement of mirrors to form an image.
The catadioptric telescope which uses mirrors combined with lenses to form an image.
A Fresnel imager is a proposed ultra-lightweight design for a space telescope that uses a Fresnel lens to focus light.
Beyond these basic optical types there are many sub-types of varying optical design classified by the task they perform such as astrographs, comet seekers and solar telescopes.
Ultraviolet
Most ultraviolet light is absorbed by the Earth's atmosphere, so observations at these wavelengths must be performed from the upper atmosphere or from space.
X-ray | Telescope | Wikipedia | 502 | 7070301 | https://en.wikipedia.org/wiki/Telescope | Technology | Optical | null |
X-rays are much harder to collect and focus than electromagnetic radiation of longer wavelengths. X-ray telescopes can use X-ray optics, such as Wolter telescopes composed of ring-shaped 'glancing' mirrors made of heavy metals that are able to reflect the rays just a few degrees. The mirrors are usually a section of a rotated parabola and a hyperbola, or ellipse. In 1952, Hans Wolter outlined 3 ways a telescope could be built using only this kind of mirror. Examples of space observatories using this type of telescope are the Einstein Observatory, ROSAT, and the Chandra X-ray Observatory. In 2012 the NuSTAR X-ray Telescope was launched which uses Wolter telescope design optics at the end of a long deployable mast to enable photon energies of 79 keV.
Gamma ray
Higher energy X-ray and gamma ray telescopes refrain from focusing completely and use coded aperture masks: the patterns of the shadow the mask creates can be reconstructed to form an image.
X-ray and Gamma-ray telescopes are usually installed on high-flying balloons or Earth-orbiting satellites since the Earth's atmosphere is opaque to this part of the electromagnetic spectrum. An example of this type of telescope is the Fermi Gamma-ray Space Telescope which was launched in June 2008.
The detection of very high energy gamma rays, with shorter wavelength and higher frequency than regular gamma rays, requires further specialization. Such detections can be made either with the Imaging Atmospheric Cherenkov Telescopes (IACTs) or with Water Cherenkov Detectors (WCDs). Examples of IACTs are H.E.S.S. and VERITAS with the next-generation gamma-ray telescope, the Cherenkov Telescope Array (CTA), currently under construction. HAWC and LHAASO are examples of gamma-ray detectors based on the Water Cherenkov Detectors.
A discovery in 2012 may allow focusing gamma-ray telescopes. At photon energies greater than 700 keV, the index of refraction starts to increase again.
Lists of telescopes
List of optical telescopes
List of largest optical reflecting telescopes
List of largest optical refracting telescopes
List of largest optical telescopes historically
List of radio telescopes
List of solar telescopes
List of space observatories
List of telescope parts and construction
List of telescope types | Telescope | Wikipedia | 464 | 7070301 | https://en.wikipedia.org/wiki/Telescope | Technology | Optical | null |
The engineering design process, also known as the engineering method, is a common series of steps that engineers use in creating functional products and processes. The process is highly iterative – parts of the process often need to be repeated many times before another can be entered – though the part(s) that get iterated and the number of such cycles in any given project may vary.
It is a decision making process (often iterative) in which the engineering sciences, basic sciences and mathematics are applied to convert resources optimally to meet a stated objective. Among the fundamental elements of the design process are the establishment of objectives and criteria, synthesis, analysis, construction, testing and evaluation.
Common stages of the engineering design process
It's important to understand that there are various framings/articulations of the engineering design process. Different terminology employed may have varying degrees of overlap, which affects what steps get stated explicitly or deemed "high level" versus subordinate in any given model. This, of course, applies as much to any particular example steps/sequences given here.
One example framing of the engineering design process delineates the following stages: research, conceptualization, feasibility assessment, establishing design requirements, preliminary design, detailed design, production planning and tool design, and production. Others, noting that "different authors (in both research literature and in textbooks) define different phases of the design process with varying activities occurring within them," have suggested more simplified/generalized models – such as problem definition, conceptual design, preliminary design, detailed design, and design communication. Another summary of the process, from European engineering design literature, includes clarification of the task, conceptual design, embodiment design, detail design. (NOTE: In these examples, other key aspects – such as concept evaluation and prototyping – are subsets and/or extensions of one or more of the listed steps.)
Research
Various stages of the design process (and even earlier) can involve a significant amount of time spent on locating information and research. Consideration should be given to the existing applicable literature, problems and successes associated with existing solutions, costs, and marketplace needs.
The source of information should be relevant. Reverse engineering can be an effective technique if other solutions are available on the market. Other sources of information include the Internet, local libraries, available government documents, personal organizations, trade journals, vendor catalogs and individual experts available. | Engineering design process | Wikipedia | 483 | 7071096 | https://en.wikipedia.org/wiki/Engineering%20design%20process | Technology | Basics | null |
Design requirements
Establishing design requirements and conducting requirement analysis, sometimes termed problem definition (or deemed a related activity), is one of the most important elements in the design process in certain industries, and this task is often performed at the same time as a feasibility analysis. The design requirements control the design of the product or process being developed, throughout the engineering design process. These include basic things like the functions, attributes, and specifications – determined after assessing user needs. Some design requirements include hardware and software parameters, maintainability, availability, and testability.
Feasibility
In some cases, a feasibility study is carried out after which schedules, resource plans and estimates for the next phase are developed. The feasibility study is an evaluation and analysis of the potential of a proposed project to support the process of decision making. It outlines and analyses alternatives or methods of achieving the desired outcome. The feasibility study helps to narrow the scope of the project to identify the best scenario.
A feasibility report is generated following which Post Feasibility Review is performed.
The purpose of a feasibility assessment is to determine whether the engineer's project can proceed into the design phase. This is based on two criteria: the project needs to be based on an achievable idea, and it needs to be within cost constraints. It is important to have engineers with experience and good judgment to be involved in this portion of the feasibility study.
Concept generation
A concept study (conceptualization, conceptual design) is often a phase of project planning that includes producing ideas and taking into account the pros and cons of implementing those ideas. This stage of a project is done to minimize the likelihood of error, manage costs, assess risks, and evaluate the potential success of the intended project. In any event, once an engineering issue or problem is defined, potential solutions must be identified. These solutions can be found by using ideation, the mental process by which ideas are generated. In fact, this step is often termed Ideation or "Concept Generation." The following are widely used techniques: | Engineering design process | Wikipedia | 404 | 7071096 | https://en.wikipedia.org/wiki/Engineering%20design%20process | Technology | Basics | null |
trigger word – a word or phrase associated with the issue at hand is stated, and subsequent words and phrases are evoked.
morphological analysis – independent design characteristics are listed in a chart, and different engineering solutions are proposed for each solution. Normally, a preliminary sketch and short report accompany the morphological chart.
synectics – the engineer imagines him or herself as the item and asks, "What would I do if I were the system?" This unconventional method of thinking may find a solution to the problem at hand. The vital aspects of the conceptualization step is synthesis. Synthesis is the process of taking the element of the concept and arranging them in the proper way. Synthesis creative process is present in every design.
brainstorming – this popular method involves thinking of different ideas, typically as part of a small group, and adopting these ideas in some form as a solution to the problem
Various generated ideas must then undergo a concept evaluation step, which utilizes various tools to compare and contrast the relative strengths and weakness of possible alternatives.
Preliminary design
The preliminary design, or high-level design includes (also called FEED or Basic design), often bridges a gap between design conception and detailed design, particularly in cases where the level of conceptualization achieved during ideation is not sufficient for full evaluation. So in this task, the overall system configuration is defined, and schematics, diagrams, and layouts of the project may provide early project configuration. (This notably varies a lot by field, industry, and product.) During detailed design and optimization, the parameters of the part being created will change, but the preliminary design focuses on creating the general framework to build the project on.
S. Blanchard and J. Fabrycky describe it as:
“The ‘whats’ initiating conceptual design produce ‘hows’ from the conceptual design evaluation effort applied to feasible conceptual design concepts. Next, the ‘hows’ are taken into preliminary design through the means of allocated requirements. There they become ‘whats’ and drive preliminary design to address ‘hows’ at this lower level.”
Detailed design
Following FEED is the Detailed Design (Detailed Engineering) phase, which may consist of procurement of materials as well.
This phase further elaborates each aspect of the project/product by complete description through solid modeling, drawings as well as specifications. | Engineering design process | Wikipedia | 466 | 7071096 | https://en.wikipedia.org/wiki/Engineering%20design%20process | Technology | Basics | null |
Computer-aided design (CAD) programs have made the detailed design phase more efficient. For example, a CAD program can provide optimization to reduce volume without hindering a part's quality. It can also calculate stress and displacement using the finite element method to determine stresses throughout the part.
Production planning
The production planning and tool design consists of planning how to mass-produce the product and which tools should be used in the manufacturing process. Tasks to complete in this step include selecting materials, selection of the production processes, determination of the sequence of operations, and selection of tools such as jigs, fixtures, metal cutting and metal or plastics forming tools. This task also involves additional prototype testing iterations to ensure the mass-produced version meets qualification testing standards.
Comparison with the scientific method
Engineering is formulating a problem that can be solved through design. Science is formulating a question that can be solved through investigation.
The engineering design process bears some similarity to the scientific method. Both processes begin with existing knowledge, and gradually become more specific in the search for knowledge (in the case of "pure" or basic science) or a solution (in the case of "applied" science, such as engineering). The key difference between the engineering process and the scientific process is that the engineering process focuses on design, creativity and innovation while the scientific process emphasizes explanation, prediction and discovery (observation).
Degree programs
Methods are being taught and developed in Universities including:
Engineering Design, University of Bristol Faculty of Engineering
Dyson School of Design Engineering, Imperial College London
TU Delft, Industrial Design Engineering.
University of Waterloo, Systems Design Engineering | Engineering design process | Wikipedia | 323 | 7071096 | https://en.wikipedia.org/wiki/Engineering%20design%20process | Technology | Basics | null |
Maja squinado (the European spider crab, spiny spider crab or spinous spider crab) is a species of migratory crab found in the Mediterranean Sea. The appearance of the European spider crab is similar to the much larger Japanese spider crab, although the European spider crab belongs to the family Majidae, and the Japanese spider crab belongs to a different family of crabs, the Macrocheiridae.
Young
The young of M. squinado are slightly longer than 1mm after hatching, and weigh approximately 0.12 mg at this time. Within 4–8 days, the larva moults numerous times, finally ending with morphological changes that presumably include the further development and increase in size of the cephalothorax. In a second phase, the Carapace grows to a length of approx. 2mm, and weighs approx. 0.3 mg.
The larva then undergoes metamorphosis to the first juvenile instar, and changes its planktonic life to a benthic one (living on the sea floor). Its appearance is also similar to that of the adult animal. From this stage only growth and the formation of sexual maturity follows. In observations under laboratory conditions, approx. 10.5% of the hatched zoea made it to this stage. The same conditions in terms of food, temperature and the like cannot be created in a laboratory. Animals in the first juvenile stage perform their first moult about 21 days after hatching, and therefore enter the second juvenile stage.
Here there is a considerable increase in the length of the carapace to approx. 4.51 mm. The second moult marks the beginning of the third juvenile stage, the animal now has the appearance of the adult, with a carapace length of approx. 5.63 mm, but is not sexually mature.
Juvenile animals spend another 2 years moulting and growing in size. The juvenile animals live in shallow water in winter, between rocks in coastal kelp forests. They spend the summer on small rocky reefs at a depth of only about 4 m. After this time, they reach a carapace length between 6–13 cm, with no noticeable sex-specific differences. During this time they are not yet sexually mature. | Maja squinado | Wikipedia | 451 | 6914315 | https://en.wikipedia.org/wiki/Maja%20squinado | Biology and health sciences | Crabs and hermit crabs | Animals |
There are two main periods for the critical moults that follow the approximately two-year period of growth leading to sexual maturity: the first, the prepubertal, in April, and the second, the pubertal, from July to October. However, in captive animals it has been noticed that in very large individuals that are in the phase before one of the two moults, one moult may be lost entirely, or be very late. Likewise, three moults have been observed on some individual specimens. The average time interval between the two critical moults is 104 days. Typically, the carapace length in animals that are already comparatively large increases less after moulting, relative to the initial size, than that of smaller animals. This also explains why there is a smaller increase in length (approx. 27%) in the pubescent moult than in the prepubertal (approx. 36%).
Behavior
Migrations generally take place in autumn, with some crabs covering over in 8 months. All crabs are vulnerable to predation when moulting, and M. squinado becomes gregarious around that time, presumably for defense against predators. Females can produce up to four broods per year. M. squinado has been documented to feed on macroalgae and benthic invertebrates. From a 1992 study done in Galicia, seaweeds from the Laminariaceae, Corallina spp., molluscs, the gastropods Bittium spp., Trochiidae, the bivalve Mytilus spp., echinoderms, and others were observed as part of the diet of this particular species.
Fishery
M. squinado is the subject of commercial fishery, with over 5,000 tonnes caught annually, more than 70% the coast of France, over 10% off the coast of the United Kingdom, 6% from the Channel Islands, 3% from each of Spain and Ireland, 2% from Croatia, 1% from Portugal, and the remainder coming from Montenegro, Denmark, and Morocco, although official production figures are open to doubt. The European Union imposes a minimum landing size of 120 mm for M. squinado, and some individual countries have other regulations, such as a ban on landing egg-bearing females in Spain and a closed season in France and the Channel Islands.
Taxonomy | Maja squinado | Wikipedia | 479 | 6914315 | https://en.wikipedia.org/wiki/Maja%20squinado | Biology and health sciences | Crabs and hermit crabs | Animals |
A review of the species complex around M. squinado was able to differentiate between specimens from the Mediterranean Sea and those from the Atlantic, and concluded that the Atlantic specimens were a separate species, called Maja brachydactyla Balss, 1922. The specific epithet squinado derives from the Provençal name for the species – , , or — recorded by Rondelet as early as 1554. | Maja squinado | Wikipedia | 83 | 6914315 | https://en.wikipedia.org/wiki/Maja%20squinado | Biology and health sciences | Crabs and hermit crabs | Animals |
The Stereospondyli are a group of extinct temnospondyl amphibians that existed primarily during the Mesozoic period. They are known from all seven continents and were common components of many Triassic ecosystems, likely filling a similar ecological niche to modern crocodilians prior to the diversification of pseudosuchian archosaurs.
Classification and anatomy
The group was first defined by Zittel (1888) on the recognition of the distinctive vertebral anatomy of the best known stereospondyls of the time, such as Mastodonsaurus and Metoposaurus. The term 'stereospondylous' as a descriptor of vertebral anatomy was coined the following year by Fraas, referring to a vertebral position consisting largely or entirely of the intercentrum in addition to the neural arch. While the name 'Stereospondyli' is derived from the stereospondylous vertebral condition, there is a diversity of vertebral morphologies among stereospondyls, including the diplospondylous ('tupilakosaurid') condition, where the arch sits between the corresponding intercentrum and pleurocentrum, and the plagiosaurid condition, where a single large centrum ossification (identity unknown) is present, and the arch sits between subsequent vertebral positions. The concept of Stereospondyli has thus undergone repeated and frequent revisions by different workers. Defining features include a tight articulation between the parasphenoid and the pterygoid and a stapedial groove. | Stereospondyli | Wikipedia | 339 | 6915193 | https://en.wikipedia.org/wiki/Stereospondyli | Biology and health sciences | Prehistoric amphibians | Animals |
Evolutionary history
Stereospondyls first definitively appeared during the early Permian, as represented by fragmentary remains of a rhinesuchid from the Pedra de Fogo Formation of Brazil. Rhinesuchids are one of the earliest groups of stereospondyls to appear in the fossil record and are predominantly a late Permian clade, with only one species, Broomistega putterilli, from the Early Triassic of South Africa. However, almost all other groups of stereospondyls are not known from any Paleozoic deposits, which remained dominated by non-stereospondyl stereospondylomorphs. The taxonomically unresolved Peltobatrachus pustulatus, which has historically been regarded as a stereospondyl, is also known from the late Permian of Tanzania. Several more fragmentary records are known from horizons spanning the Permo-Triassic boundary in South America, such as the rhinesuchid-like Arachana nigra from Uruguay and an indeterminate mastodonsaurid from Uruguay.
Following the Permo-Triassic mass extinction, stereospondyls are abundantly represented in the fossil record, particularly from Russia, South Africa, and Australia. This led Yates & Warren (2000) to propose that stereospondyls had sheltered in a high-latitude refugium that would have been somewhat shielded from the global effects of the extinction, and that they subsequently radiated from present-day Australia or Antarctica. Recent discoveries of a diverse rhinesuchid community in South America alongside non-stereospondyl stereospondylomorphs have led to an alternative hypothesis for a radiation from western Gondwana in South America. By the end of the Early Triassic, virtually all major clades of stereospondyls had appeared in the fossil record, although some were more geographically localized (e.g., lapillopsids, rhytidosteids) than those with cosmopolitan distributions (e.g., capitosauroids, trematosauroids). | Stereospondyli | Wikipedia | 423 | 6915193 | https://en.wikipedia.org/wiki/Stereospondyli | Biology and health sciences | Prehistoric amphibians | Animals |
Stereospondyls were the latest-surviving temnospondyl group. With the diversification of crocodile-like archosaurs and an extinction event at the end of the Triassic, most other temnospondyls disappeared. Chigutisaurid brachyopoids persisted into the Jurassic in Asia and Australia, including Koolasuchus, the youngest known stereospondyl (late Early Cretaceous) from what is now Australia. There is also sparse evidence for the persistence of some trematosauroids into the Jurassic of Asia. If the recent hypothesis that Chinlestegophis, a Late Triassic stereospondyl from North America, is indeed a stem caecilian is correct, then stereospondyls would survive to the present day.
Lifestyle and ecology
Stereospondyls were particularly diverse during the Early Triassic, with small-bodied taxa such as lapillopsids and lydekkerinids that were likely more terrestrially capable present alongside larger taxa that would continue into the Middle Triassic, such as brachyopoids and trematosauroids. The vast majority of stereospondyls, particularly the large-bodied taxa, have been inferred to have been obligately aquatic based on features of the external anatomy such as a well-developed lateral line system, poorly ossified postcranial skeleton, and occasional preservation of proxies of external gills. Many taxa also reflect adaptations for an aquatic lifestyle as evidence in bone histology, which is pachyostotic in many taxa, although some studies suggest a greater terrestrial ability than historically inferred. Most of the aquatic taxa resided in freshwater environments, but some trematosauroids in particular are thought to have been euryhaline based on their preservation in marine sediments with marine organisms. While stereospondyls are often compared to modern crocodilians, the presence of multiple temnospondyls in some environments and the range of morphologies across Stereospondyli indicates that at least some clades occupied drastically different ecological niches, such as benthic ambush predators. Some groups, such as metoposaurids, are often recovered from large monotaxic bone beds interpreted as evidence of aggregation prior to mass death.
Relationships
Phylogeny
Gallery | Stereospondyli | Wikipedia | 473 | 6915193 | https://en.wikipedia.org/wiki/Stereospondyli | Biology and health sciences | Prehistoric amphibians | Animals |
Soil salinity control refers to controlling the process and progress of soil salinity to prevent soil degradation by salination and reclamation of already salty (saline) soils. Soil reclamation is also known as soil improvement, rehabilitation, remediation, recuperation, or amelioration.
The primary man-made cause of salinization is irrigation. River water or groundwater used in irrigation contains salts, which remain in the soil after the water has evaporated.
The primary method of controlling soil salinity is to permit 10–20% of the irrigation water to leach the soil, so that it will be drained and discharged through an appropriate drainage system. The salt concentration of the drainage water is normally 5 to 10 times higher than that of the irrigation water which meant that salt export will more closely match salt import and it will not accumulate.
Problems with soil salinity
Salty (saline) soils have high salt content. The predominant salt is normally sodium chloride (NaCl, "table salt"). Saline soils are therefore also sodic soils but there may be sodic soils that are not saline, but alkaline.
According to a study by UN University, about , representing 20% of the world's irrigated lands are affected, up from in the early 1990s. In the Indo-Gangetic Plain, home to over 10% of the world's population, crop yield losses for wheat, rice, sugarcane and cotton grown on salt-affected lands could be 40%, 45%, 48%, and 63%, respectively.
Salty soils are a common feature and an environmental problem in irrigated lands in arid and semi-arid regions, resulting in poor or little crop production. The causes of salty soils are often associated with high water tables, which are caused by a lack of natural subsurface drainage to the underground. Poor subsurface drainage may be caused by insufficient transport capacity of the aquifer or because water cannot exit the aquifer, for instance, if the aquifer is situated in a topographical depression.
Worldwide, the major factor in the development of saline soils is a lack of precipitation. Most naturally saline soils are found in (semi) arid regions and climates of the earth.
Primary cause
Man-made salinization is primarily caused by salt found in irrigation water. All irrigation water derived from rivers or groundwater, regardless of water purity, contains salts that remain behind in the soil after the water has evaporated. | Soil salinity control | Wikipedia | 500 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
For example, assuming irrigation water with a low salt concentration of 0.3 g/L (equal to 0.3 kg/m3 corresponding to an electric conductivity of about 0.5 FdS/m) and a modest annual supply of irrigation water of 10,000 m3/ha (almost 3 mm/day) brings 3,000 kg salt/ha each year. With the absence of sufficient natural drainage (as in waterlogged soils), and proper leaching and drainage program to remove salts, this would lead to high soil salinity and reduced crop yields in the long run.
Much of the water used in irrigation has a higher salt content than 0.3 g/L, compounded by irrigation projects using a far greater annual supply of water. Sugar cane, for example, needs about 20,000 m3/ha of water per year. As a result, irrigated areas often receive more than 3,000 kg/ha of salt per year, with some receiving as much as 10,000 kg/ha/year.
Secondary cause
The secondary cause of salinization is waterlogging in irrigated land. Irrigation causes changes to the natural water balance of irrigated lands. Large quantities of water in irrigation projects are not consumed by plants and must go somewhere. In irrigation projects, it is impossible to achieve 100% irrigation efficiency where all the irrigation water is consumed by the plants. The maximum attainable irrigation efficiency is about 70%, but usually, it is less than 60%. This means that minimum 30%, but usually more than 40% of the irrigation water is not evaporated and it must go somewhere.
Most of the water lost this way is stored underground which can change the original hydrology of local aquifers considerably. Many aquifers cannot absorb and transport these quantities of water, and so the water table rises leading to waterlogging.
Waterlogging causes three problems:
The shallow water table and lack of oxygenation of the root zone reduces the yield of most crops.
It leads to an accumulation of salts brought in with the irrigation water as their removal through the aquifer is blocked.
With the upward seepage of groundwater, more salts are brought into the soil and the salination is aggravated.
Aquifer conditions in irrigated land and the groundwater flow have an important role in soil salinization, as illustrated here: | Soil salinity control | Wikipedia | 484 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
Salt affected area
Normally, the salinization of agricultural land affects a considerable area of 20% to 30% in irrigation projects. When the agriculture in such a fraction of the land is abandoned, a new salt and water balance is attained, a new equilibrium is reached and the situation becomes stable.
In India alone, thousands of square kilometers have been severely salinized. China and Pakistan do not lag far behind (perhaps China has even more salt affected land than India). A regional distribution of the 3,230,000 km2 of saline land worldwide is shown in the following table derived from the FAO/UNESCO Soil Map of the World.
Spatial variation
Although the principles of the processes of salinization are fairly easy to understand, it is more difficult to explain why certain parts of the land suffer from the problems and other parts do not, or to predict accurately which part of the land will fall victim. The main reason for this is the variation of natural conditions in time and space, the usually uneven distribution of the irrigation water, and the seasonal or yearly changes of agricultural practices. Only in lands with undulating topography is the prediction simple: the depressional areas will degrade the most.
The preparation of salt and water balances for distinguishable sub-areas in the irrigation project, or the use of agro-hydro-salinity models, can be helpful in explaining or predicting the extent and severity of the problems.
Diagnosis
Measurement
Soil salinity is measured as the salt concentration of the soil solution in tems of g/L or electric conductivity (EC) in dS/m. The relation between these two units is about 5/3: y g/L => 5y/3 dS/m. Seawater may have a salt concentration of 30 g/L (3%) and an EC of 50 dS/m.
The standard for the determination of soil salinity is from an extract of a saturated paste of the soil, and the EC is then written as ECe. The extract is obtained by centrifugation. The salinity can more easily be measured, without centrifugation, in a 2:1 or 5:1 water:soil mixture (in terms of g water per g dry soil) than from a saturated paste. The relation between ECe and EC2:1 is about 4, hence: ECe = 4EC1:2. | Soil salinity control | Wikipedia | 488 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
Classification
Soils are considered saline when the ECe > 4. When 4 < ECe < 8, the soil is called slightly saline, when 8 < ECe < 16 it is called (moderately) saline, and when ECe > 16 severely saline.
Crop tolerance
Sensitive crops lose their vigor already in slightly saline soils; most crops are negatively affected by (moderately) saline soils, and only salinity resistant crops thrive in severely saline soils. The University of Wyoming and the Government of Alberta report data on the salt tolerance of plants.
Principles of salinity control
Drainage is the primary method of controlling soil salinity. The system should permit a small fraction of the irrigation water (about 10 to 20 percent, the drainage or leaching fraction) to be drained and discharged out of the irrigation project.
In irrigated areas where salinity is stable, the salt concentration of the drainage water is normally 5 to 10 times higher than that of the irrigation water. Salt export matches salt import and salt will not accumulate.
When reclaiming already salinized soils, the salt concentration of the drainage water will initially be much higher than that of the irrigation water (for example 50 times higher). Salt export will greatly exceed salt import, so that with the same drainage fraction a rapid desalinization occurs. After one or two years, the soil salinity is decreased so much, that the salinity of the drainage water has come down to a normal value and a new, favorable, equilibrium is reached.
In regions with pronounced dry and wet seasons, the drainage system may be operated in the wet season only, and closed during the dry season. This practice of checked or controlled drainage saves irrigation water.
The discharge of salty drainage water may pose environmental problems to downstream areas. The environmental hazards must be considered very carefully and, if necessary mitigating measures must be taken. If possible, the drainage must be limited to wet seasons only, when the salty effluent inflicts the least harm.
Drainage systems
Land drainage for soil salinity control is usually by horizontal drainage system (figure left), but vertical systems (figure right) are also employed.
The drainage system designed to evacuate salty water also lowers the water table. To reduce the cost of the system, the lowering must be reduced to a minimum. The highest permissible level of the water table (or the shallowest permissible depth) depends on the irrigation and agricultural practices and kind of crops. | Soil salinity control | Wikipedia | 498 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
In many cases a seasonal average water table depth of 0.6 to 0.8 m is deep enough. This means that the water table may occasionally be less than 0.6 m (say 0.2 m just after an irrigation or a rain storm). This automatically implies that, in other occasions, the water table will be deeper than 0.8 m (say 1.2 m). The fluctuation of the water table helps in the breathing function of the soil while the expulsion of carbon dioxide (CO2) produced by the plant roots and the inhalation of fresh oxygen (O2) is promoted.
The establishing of a not-too-deep water table offers the additional advantage that excessive field irrigation is discouraged, as the crop yield would be negatively affected by the resulting elevated water table, and irrigation water may be saved.
The statements made above on the optimum depth of the water table are very general, because in some instances the required water table may be still shallower than indicated (for example in rice paddies), while in other instances it must be considerably deeper (for example in some orchards). The establishment of the optimum depth of the water table is in the realm of agricultural drainage criteria.
Soil leaching | Soil salinity control | Wikipedia | 252 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
The vadose zone of the soil below the soil surface and the water table is subject to four main hydrological inflow and outflow factors:
Infiltration of rain and irrigation water (Irr) into the soil through the soil surface (Inf) :
Inf = Rain + Irr
Evaporation of soil water through plants and directly into the air through the soil surface (Evap)
Percolation of water from the unsaturated zone soil into the groundwater through the watertable (Perc)
Capillary rise of groundwater moving by capillary suction forces into the unsaturated zone (Cap)
In steady state (i.e. the amount of water stored in the unsaturated zone does not change in the long run) the water balance of the unsaturated zone reads: Inflow = Outflow, thus:
Inf + Cap = Evap + Perc or:
Irr + Rain + Cap = Evap + Perc
and the salt balance is
Irr.Ci + Cap.Cc = Evap.Fc.Ce + Perc.Cp + Ss
where Ci is the salt concentration of the irrigation water, Cc is the salt concentration of the capillary rise, equal to the salt concentration of the upper part of the groundwater body, Fc is the fraction of the total evaporation transpired by plants, Ce is the salt concentration of the water taken up by the plant roots, Cp is the salt concentration of the percolation water, and Ss is the increase of salt storage in the unsaturated soil. This assumes that the rainfall contains no salts. Only along the coast this may not be true. Further it is assumed that no runoff or surface drainage occurs. The amount of removed by plants (Evap.Fc.Ce) is usually negligibly small: Evap.Fc.Ce = 0 | Soil salinity control | Wikipedia | 384 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
The salt concentration Cp can be taken as a part of the salt concentration of the soil in the unsaturated zone (Cu) giving: Cp = Le.Cu, where Le is the leaching efficiency. The leaching efficiency is often in the order of 0.7 to 0.8, but in poorly structured, heavy clay soils it may be less. In the Leziria Grande polder in the delta of the Tagus river in Portugal it was found that the leaching efficiency was only 0.15.
Assuming that one wishes to avoid the soil salinity to increase and maintain the soil salinity Cu at a desired level Cd we have:
Ss = 0, Cu = Cd and Cp = Le.Cd. Hence the salt balance can be simplified to:
Perc.Le.Cd = Irr.Ci + Cap.Cc
Setting the amount percolation water required to fulfill this salt balance equal to Lr (the leaching requirement) it is found that:
Lr = (Irr.Ci + Cap.Cc) / Le.Cd .
Substituting herein Irr = Evap + Perc − Rain − Cap and re-arranging gives :
Lr = [ (Evap−Rain).Ci + Cap(Cc−Ci) ] / (Le.Cd − Ci)
With this the irrigation and drainage requirements for salinity control can be computed too.
In irrigation projects in (semi)arid zones and climates it is important to check the leaching requirement, whereby the field irrigation efficiency (indicating the fraction of irrigation water percolating to the underground) is to be taken into account.
The desired soil salinity level Cd depends on the crop tolerance to salt. The University of Wyoming, US, and the Government of Alberta, Canada, report crop tolerance data.
Strip cropping: an alternative
In irrigated lands with scarce water resources suffering from drainage (high water table) and soil salinity problems, strip cropping is sometimes practiced with strips of land where every other strip is irrigated while the strips in between are left permanently fallow. | Soil salinity control | Wikipedia | 428 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
Owing to the water application in the irrigated strips they have a higher water table which induces flow of groundwater to the unirrigated strips. This flow functions as subsurface drainage for the irrigated strips, whereby the water table is maintained at a not-too-shallow depth, leaching of the soil is possible, and the soil salinity can be controlled at an acceptably low level.
In the unirrigated (sacrificial) strips the soil is dry and the groundwater comes up by capillary rise and evaporates leaving the salts behind, so that here the soil salinizes. Nevertheless, they can have some use for livestock, sowing salinity resistant grasses or weeds. Moreover, useful salt resistant trees can be planted like Casuarina, Eucalyptus, or Atriplex, keeping in mind that the trees have deep rooting systems and the salinity of the wet subsoil is less than of the topsoil. In these ways wind erosion can be controlled. The unirrigated strips can also be used for salt harvesting.
Soil salinity models
The majority of the computer models available for water and solute transport in the soil (e.g. SWAP, DrainMod-S, UnSatChem, and Hydrus) are based on Richard's differential equation for the movement of water in unsaturated soil in combination with Fick's differential convection–diffusion equation for advection and dispersion of salts.
The models require the input of soil characteristics like the relations between variable unsaturated soil moisture content, water tension, water retention curve, unsaturated hydraulic conductivity, dispersity, and diffusivity. These relations vary greatly from place to place and time to time and are not easy to measure. Further, the models are complicated to calibrate under farmer's field conditions because the soil salinity here is spatially very variable. The models use short time steps and need at least a daily, if not hourly, database of hydrological phenomena. Altogether, this makes model application to a fairly large project the job of a team of specialists with ample facilities.
Simpler models, like SaltMod, based on monthly or seasonal water and soil balances and an empirical capillary rise function, are also available. They are useful for long-term salinity predictions in relation to irrigation and drainage practices. | Soil salinity control | Wikipedia | 501 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
LeachMod, Using the SaltMod principles helps in analyzing leaching experiments in which the soil salinity was monitored in various root zone layers while the model will optimize the value of the leaching efficiency of each layer so that a fit is obtained of observed with simulated soil salinity values.
Spatial variations owing to variations in topography can be simulated and predicted using salinity cum groundwater models, like SahysMod. | Soil salinity control | Wikipedia | 89 | 11671698 | https://en.wikipedia.org/wiki/Soil%20salinity%20control | Technology | Soil and soil management | null |
Marine ecosystems are the largest of Earth's aquatic ecosystems and exist in waters that have a high salt content. These systems contrast with freshwater ecosystems, which have a lower salt content. Marine waters cover more than 70% of the surface of the Earth and account for more than 97% of Earth's water supply and 90% of habitable space on Earth. Seawater has an average salinity of 35 parts per thousand of water. Actual salinity varies among different marine ecosystems. Marine ecosystems can be divided into many zones depending upon water depth and shoreline features. The oceanic zone is the vast open part of the ocean where animals such as whales, sharks, and tuna live. The benthic zone consists of substrates below water where many invertebrates live. The intertidal zone is the area between high and low tides. Other near-shore (neritic) zones can include mudflats, seagrass meadows, mangroves, rocky intertidal systems, salt marshes, coral reefs, lagoons. In the deep water, hydrothermal vents may occur where chemosynthetic sulfur bacteria form the base of the food web. Marine ecosystems are characterized by the biological community of organisms that they are associated with and their physical environment. Classes of organisms found in marine ecosystems include brown algae, dinoflagellates, corals, cephalopods, echinoderms, and sharks.
Marine ecosystems are important sources of ecosystem services and food and jobs for significant portions of the global population. Human uses of marine ecosystems and pollution in marine ecosystems are significantly threats to the stability of these ecosystems. Environmental problems concerning marine ecosystems include unsustainable exploitation of marine resources (for example overfishing of certain species), marine pollution, climate change, and building on coastal areas. Moreover, much of the carbon dioxide causing global warming and heat captured by global warming are absorbed by the ocean, ocean chemistry is changing through processes like ocean acidification which in turn threatens marine ecosystems.
Because of the opportunities in marine ecosystems for humans and the threats created by humans, the international community has prioritized "Life below water" as Sustainable Development Goal 14. The goal is to "Conserve and sustainably use the oceans, seas and marine resources for sustainable development".
Types or locations
Marine coastal ecosystems
Coral reefs | Marine ecosystem | Wikipedia | 462 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Coral reefs are one of the most well-known marine ecosystems in the world, with the largest being the Great Barrier Reef. These reefs are composed of large coral colonies of a variety of species living together. The corals form multiple symbiotic relationships with the organisms around them.
Mangroves
Mangroves are trees or shrubs that grow in low-oxygen soil near coastlines in tropical or subtropical latitudes. They are an extremely productive and complex ecosystem that connects the land and sea. Mangroves consist of species that are not necessarily related to each other and are often grouped for the characteristics they share rather than genetic similarity. Because of their proximity to the coast, they have all developed adaptions such as salt excretion and root aeration to live in salty, oxygen-depleted water. Mangroves can often be recognized by their dense tangle of roots that act to protect the coast by reducing erosion from storm surges, currents, wave, and tides. The mangrove ecosystem is also an important source of food for many species as well as excellent at sequestering carbon dioxide from the atmosphere with global mangrove carbon storage is estimated at 34 million metric tons per year.
Seagrass meadows
Seagrasses form dense underwater meadows which are among the most productive ecosystems in the world. They provide habitats and food for a diversity of marine life comparable to coral reefs. This includes invertebrates like shrimp and crabs, cod and flatfish, marine mammals and birds. They provide refuges for endangered species such as seahorses, turtles, and dugongs. They function as nursery habitats for shrimps, scallops and many commercial fish species. Seagrass meadows provide coastal storm protection by the way their leaves absorb energy from waves as they hit the coast. They keep coastal waters healthy by absorbing bacteria and nutrients, and slow the speed of climate change by sequestering carbon dioxide into the sediment of the ocean floor.
Seagrasses evolved from marine algae which colonized land and became land plants, and then returned to the ocean about 100 million years ago. However, today seagrass meadows are being damaged by human activities such as pollution from land runoff, fishing boats that drag dredges or trawls across the meadows uprooting the grass, and overfishing which unbalances the ecosystem. Seagrass meadows are currently being destroyed at a rate of about two football fields every hour.
Kelp forests
Kelp forests occur worldwide throughout temperate and polar coastal oceans. In 2007, kelp forests were also discovered in tropical waters near Ecuador. | Marine ecosystem | Wikipedia | 505 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Physically formed by brown macroalgae, kelp forests provide a unique habitat for marine organisms and are a source for understanding many ecological processes. Over the last century, they have been the focus of extensive research, particularly in trophic ecology, and continue to provoke important ideas that are relevant beyond this unique ecosystem. For example, kelp forests can influence coastal oceanographic patterns and provide many ecosystem services.
However, the influence of humans has often contributed to kelp forest degradation. Of particular concern are the effects of overfishing nearshore ecosystems, which can release herbivores from their normal population regulation and result in the overgrazing of kelp and other algae. This can rapidly result in transitions to barren landscapes where relatively few species persist. Already due to the combined effects of overfishing and climate change, kelp forests have all but disappeared in many especially vulnerable places, such as Tasmania's east coast and the coast of Northern California. The implementation of marine protected areas is one management strategy useful for addressing such issues, since it may limit the impacts of fishing and buffer the ecosystem from additive effects of other environmental stressors.
Estuaries
Estuaries occur where there is a noticeable change in salinity between saltwater and freshwater sources. This is typically found where rivers meet the ocean or sea. The wildlife found within estuaries is unique as the water in these areas is brackish - a mix of freshwater flowing to the ocean and salty seawater. Other types of estuaries also exist and have similar characteristics as traditional brackish estuaries. The Great Lakes are a prime example. There, river water mixes with lake water and creates freshwater estuaries. Estuaries are extremely productive ecosystems that many humans and animal species rely on for various activities. This can be seen as, of the 32 largest cities in the world, 22 are located on estuaries as they provide many environmental and economic benefits such as crucial habitat for many species, and being economic hubs for many coastal communities. Estuaries also provide essential ecosystem services such as water filtration, habitat protection, erosion control, gas regulation nutrient cycling, and it even gives education, recreation and tourism opportunities to people.
Lagoons | Marine ecosystem | Wikipedia | 441 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Lagoons are areas that are separated from larger water by natural barriers such as coral reefs or sandbars. There are two types of lagoons, coastal and oceanic/atoll lagoons. A coastal lagoon is, as the definition above, simply a body of water that is separated from the ocean by a barrier. An atoll lagoon is a circular coral reef or several coral islands that surround a lagoon. Atoll lagoons are often much deeper than coastal lagoons. Most lagoons are very shallow meaning that they are greatly affected by changed in precipitation, evaporation and wind. This means that salinity and temperature are widely varied in lagoons and that they can have water that ranges from fresh to hypersaline. Lagoons can be found in on coasts all over the world, on every continent except Antarctica and is an extremely diverse habitat being home to a wide array of species including birds, fish, crabs, plankton and more. Lagoons are also important to the economy as they provide a wide array of ecosystem services in addition to being the home of so many different species. Some of these services include fisheries, nutrient cycling, flood protection, water filtration, and even human tradition.
Salt marsh
Salt marshes are a transition from the ocean to the land, where fresh and saltwater mix. The soil in these marshes is often made up of mud and a layer of organic material called peat. Peat is characterized as waterlogged and root-filled decomposing plant matter that often causes low oxygen levels (hypoxia). These hypoxic conditions causes growth of the bacteria that also gives salt marshes the sulfurous smell they are often known for. Salt marshes exist around the world and are needed for healthy ecosystems and a healthy economy. They are extremely productive ecosystems and they provide essential services for more than 75 percent of fishery species and protect shorelines from erosion and flooding. Salt marshes can be generally divided into the high marsh, low marsh, and the upland border. The low marsh is closer to the ocean, with it being flooded at nearly every tide except low tide. The high marsh is located between the low marsh and the upland border and it usually only flooded when higher than usual tides are present. The upland border is the freshwater edge of the marsh and is usually located at elevations slightly higher than the high marsh. This region is usually only flooded under extreme weather conditions and experiences much less waterlogged conditions and salt stress than other areas of the marsh.
Intertidal zones | Marine ecosystem | Wikipedia | 501 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Intertidal zones are the areas that are visible and exposed to air during low tide and covered up by saltwater during high tide. There are four physical divisions of the intertidal zone with each one having its distinct characteristics and wildlife. These divisions are the Spray zone, High intertidal zone, Middle Intertidal zone, and Low intertidal zone. The Spray zone is a damp area that is usually only reached by the ocean and submerged only under high tides or storms. The high intertidal zone is submerged at high tide but remains dry for long periods between high tides. Due to the large variance of conditions possible in this region, it is inhabited by resilient wildlife that can withstand these changes such as barnacles, marine snails, mussels and hermit crabs. Tides flow over the middle intertidal zone two times a day and this zone has a larger variety of wildlife. The low intertidal zone is submerged nearly all the time except during the lowest tides and life is more abundant here due to the protection that the water gives.
Ocean surface
Organisms that live freely at the surface, termed neuston, include keystone organisms like the golden seaweed Sargassum that makes up the Sargasso Sea, floating barnacles, marine snails, nudibranchs, and cnidarians. Many ecologically and economically important fish species live as or rely upon neuston. Species at the surface are not distributed uniformly; the ocean's surface harbours unique neustonic communities and ecoregions found at only certain latitudes and only in specific ocean basins. But the surface is also on the front line of climate change and pollution. Life on the ocean's surface connects worlds. From shallow waters to the deep sea, the open ocean to rivers and lakes, numerous terrestrial and marine species depend on the surface ecosystem and the organisms found there. | Marine ecosystem | Wikipedia | 381 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
The ocean's surface acts like a skin between the atmosphere above and the water below, and harbours an ecosystem unique to this environment. This sun-drenched habitat can be defined as roughly one metre in depth, as nearly half of UV-B is attenuated within this first meter. Organisms here must contend with wave action and unique chemical and physical properties. The surface is utilised by a wide range of species, from various fish and cetaceans, to species that ride on ocean debris (termed rafters). Most prominently, the surface is home to a unique community of free-living organisms, termed neuston (from the Greek word, υεω, which means both to swim and to float. Floating organisms are also sometimes referred to as pleuston, though neuston is more commonly used). Despite the diversity and importance of the ocean's surface in connecting disparate habitats, and the risks it faces, not a lot is known about neustonic life.
A stream of airborne microorganisms circles the planet above weather systems but below commercial air lanes. Some peripatetic microorganisms are swept up from terrestrial dust storms, but most originate from marine microorganisms in sea spray. In 2018, scientists reported that hundreds of millions of viruses and tens of millions of bacteria are deposited daily on every square meter around the planet.
Deep sea and sea floor
The deep sea contains up to 95% of the space occupied by living organisms. Combined with the sea floor (or benthic zone), these two areas have yet to be fully explored and have their organisms documented.
Large marine ecosystems
In 1984, National Oceanic and Atmospheric Administration (NOAA) of the United States developed the concept of large marine ecosystems (sometimes abbreviated to LMEs), to identify areas of the oceans for environmental conservation purposes and to enable collaborative ecosystem-based management in transnational areas, in a way consistent with the 1982 UN Convention on the Law of the Sea. This name refers to relatively large regions on the order of or greater, characterized by their distinct bathymetry, hydrography, productivity, and trophically dependent populations. Such LMEs encompass coastal areas from river basins and estuaries to the seaward boundaries of continental shelves and the outer margins of the major ocean current systems. | Marine ecosystem | Wikipedia | 469 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Altogether, there are 66 LMEs, which contribute an estimated $3 trillion annually. This includes being responsible for 90% of global annual marine fishery biomass. LME-based conservation is based on recognition that the world's coastal ocean waters are degraded by unsustainable fishing practices, habitat degradation, eutrophication, toxic pollution, aerosol contamination, and emerging diseases, and that positive actions to mitigate these threats require coordinated actions by governments and civil society to recover depleted fish populations, restore degraded habitats and reduce coastal pollution. Five modules are considered when assessing LMEs: productivity, fish and fisheries, pollution and ecosystem health, socioeconomics, and governance. Periodically assessing the state of each module within a marine LME is encouraged to ensure maintained health of the ecosystem and future benefit to managing governments. The Global Environment Facility (GEF) aids in managing LMEs off the coasts of Africa and Asia by creating resource management agreements between environmental, fisheries, energy and tourism ministers of bordering countries. This means participating countries share knowledge and resources pertaining to local LMEs to promote longevity and recovery of fisheries and other industries dependent upon LMEs.
Large marine ecosystems include:
East Bering Sea
Gulf of Alaska
California Current
Gulf of California
Gulf of Mexico
Southeast U.S. Continental Shelf
Northeast U.S. Continental Shelf
Scotian Shelf
Newfoundland-Labrador Shelf
Insular Pacific-Hawaiian
Pacific Central-American Coastal
Caribbean Sea
Humboldt Current
Patagonian Shelf
South Brazil Shelf
East Brazil Shelf
North Brazil Shelf
West Greenland Shelf
East Greenland Shelf
Barents Sea
Norwegian Shelf
North Sea
Baltic Sea
Celtic-Biscay Shelf
Central Arctic
Iberian Coastal
Mediterranean Sea
Canary Current
Guinea Current
Benguela Current
Agulhas Current
Somali Coastal Current
Arabian Sea
Red Sea
Bay of Bengal
Gulf of Thailand
South China Sea
Sulu-Celebes Sea
Indonesian Sea
North Australian Shelf
Northeast Australian Shelf/Great Barrier Reef
East-Central Australian Shelf
Southeast Australian Shelf
Southwest Australian Shelf
West-Central Australian Shelf
Northwest Australian Shelf
New Zealand Shelf
East China Sea
Yellow Sea
Kuroshio Current
Sea of Japan
Oyashio Current
Sea of Okhotsk
West Bering Sea
Chukchi Sea
Beaufort Sea
East Siberian Sea
Laptev Sea
Kara Sea
Iceland Shelf
Faroe Plateau
Antarctica
Black Sea
Hudson Bay
Arctic Ocean
Greenland Sea
Role in ecosystem services | Marine ecosystem | Wikipedia | 453 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
In addition to providing many benefits to the natural world, marine ecosystems also provide social, economic, and biological ecosystem services to humans. Pelagic marine systems regulate the global climate, contribute to the water cycle, maintain biodiversity, provide food and energy resources, and create opportunities for recreation and tourism. Economically, marine systems support billions of dollars worth of capture fisheries, aquaculture, offshore oil and gas, and trade and shipping.
Ecosystem services fall into multiple categories, including supporting services, provisioning services, regulating services, and cultural services.
The productivity of a marine ecosystem can be measured in several ways. Measurements pertaining to zooplankton biodiversity and species composition, zooplankton biomass, water-column structure, photosynthetically active radiation, transparency, chlorophyll-a, nitrate, and primary production are used to assess changes in LME productivity and potential fisheries yield. Sensors attached to the bottom of ships or deployed on floats can measure these metrics and be used to quantitatively describe changes in productivity alongside physical changes in the water column such as temperature and salinity. This data can be used in conjunction with satellite measurements of chlorophyll and sea surface temperatures to validate measurements and observe trends on greater spatial and temporal scales.
Bottom-trawl surveys and pelagic-species acoustic surveys are used to assess changes in fish biodiversity and abundance in LMEs. Fish populations can be surveyed for stock identification, length, stomach content, age-growth relationships, fecundity, coastal pollution and associated pathological conditions, as well as multispecies trophic relationships. Fish trawls can also collect sediment and inform us about ocean-bottom conditions such as anoxia.
Threats
Human exploitation and development
Coastal marine ecosystems experience growing population pressures with nearly 40% of people in the world living within 100 km of the coast. Humans often aggregate near coastal habitats to take advantage of ecosystem services. For example, coastal capture fisheries from mangroves and coral reef habitats are estimated to be worth a minimum of $34 billion per year. Yet, many of these habitats are either marginally protected or not protected. Mangrove area has declined worldwide by more than one-third since 1950, and 60% of the world's coral reefs are now immediately or directly threatened. Human development, aquaculture, and industrialization often lead to the destruction, replacement, or degradation of coastal habitats. | Marine ecosystem | Wikipedia | 488 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
Moving offshore, pelagic marine systems are directly threatened by overfishing. Global fisheries landings peaked in the late 1980s, but are now declining, despite increasing fishing effort. Fish biomass and average trophic level of fisheries landing are decreasing, leading to declines in marine biodiversity. In particular, local extinctions have led to declines in large, long-lived, slow-growing species, and those that have narrow geographic ranges. Biodiversity declines can lead to associated declines in ecosystem services. A long-term study reports the decline of 74–92% of catch per unit effort of sharks in Australian coastline from the 1960s to 2010s. Such biodiversity losses impact not just species themselves, but humans as well, and can contribute to climate change across the globe. The National Oceanic and Atmospheric Administration (NOAA) states that managing and protecting marine ecosystems is crucial in attempting to conserve biodiversity in the face of Earth’s rapidly changing climate.
Pollution
Invasive species
Global aquarium trade
Ballast water transport
Aquaculture
Climate change
Warming temperatures (see ocean heat content, sea surface temperature, and marine heat wave)
Increased frequency/intensity of storms
Ocean acidification
Sea level rise
Society and culture
Global goals
By integrating socioeconomic metrics with ecosystem management solutions, scientific findings can be utilized to benefit both the environment and economy of local regions. Management efforts must be practical and cost-effective. In 2000, the Department of Natural Resource Economics at the University of Rhode Island has created a method for measuring and understanding the human dimensions of LMEs and for taking into consideration both socioeconomic and environmental costs and benefits of managing Large Marine Ecosystems.
International attention to address the threats of coasts has been captured in Sustainable Development Goal 14 "Life Below Water" which sets goals for international policy focused on preserving coastal ecosystems and supporting more sustainable economic practices for coastal communities. Furthermore, the United Nations has declared 2021-2030 the UN Decade on Ecosystem Restoration, but restoration of coastal ecosystems has received insufficient attention. | Marine ecosystem | Wikipedia | 387 | 5411659 | https://en.wikipedia.org/wiki/Marine%20ecosystem | Physical sciences | Oceanography | Earth science |
The term coldwater fish can have different meanings in different contexts.
In the context of fishkeeping, it refers to ornamental fish species that tolerate the temperatures of a typical indoor aquarium well and do not require a heater to remain active, as opposed to tropical fish whom need a heater to survive in the room temperatures of temperate climates;
In the context of ecology and fishing, it refers to fish species that prefer to inhabit waterbodies or depth zones with much lower temperatures than the average temperate water. Salmonids (e.g. salmon, trout, char and graylings) are a classic example of such types of fish.
Fishkeeping
Most or all ornamental fish species are able to tolerate temperatures as low as or lower than room temperature, with most stenothermic tropical species having critical thermal minimums of around 10-12 °C. Although these fish are capable of surviving in unheated aquaria, their temperature preferences may vary. For example, koi, goldfish, and pond loaches are commonly considered to be cold-water fish because of their ability to survive at very low temperatures, but their temperature preferences and/or physiological optimal temperatures are , , and , respectively. Because many of the ornamental fish considered to be “coldwater fish” are more accurately eurythermal fish and many prefer temperatures similar to, or even warmer than those preferred by certain tropical fish, the term “coldwater fish” in the aquarium context often misleads pet owners into keeping fish below their preferred temperature.
Freshwater aquarium fish | Coldwater fish | Wikipedia | 306 | 2943192 | https://en.wikipedia.org/wiki/Coldwater%20fish | Biology and health sciences | Fishes by habitat | Animals |
Southern redbelly dace
Lepomis
Shubunkin
Comet goldfish
Common goldfish
Fancy goldfish
Black telescope
Fantail goldfish
Oranda
Ryukin
Weather loach
White Cloud Mountain minnow
Celestial Pearl Danio
Buenos Aires tetra
Gold barb
Rosy barb
Odessa barb
Fathead minnow
Banded corydoras
Chinese high fin banded shark
Three-spined stickleback
Ticto barb
Pygmy sunfish
Enneacanthus
Texas cichlid
Paradise fish
Green barb
Zebra danio
Bengal danio
Leopard danio
Danio tinwini
Bulldog pleco
Rhinogobius
Desert goby
Highland swordtail (Xiphophorus malinche)
Japanese ricefish
Zacco
Black lined loach (Yasuhikotakia nigrolineata)
Red shiner (Cyprinella lutrensis)
Spotted gar
Longnose gar
Rosy red minnow
Hillstream loach
Spined loach
Stone loach
Common minnow
Vietnamese cardinal minnow
GM glowing medaka
Gobio
Amur bitterling
Rosy bitterling
Light's bitterling
Deep bodied bitterling
Rainbow shiner (Notropsis chromosus)
Black shark (not to be confused with the tropical red tailed black shark)
Golden cobra snakehead
Dwarf snakehead
Rainbow snakehead
Spotted snakehead (Channa punctata)
Pearl danio
Northern snakehead
Chinese algae eater
Variable platyfish
Note: The above contains a mix of true coldwater fish and sub-tropical fish that can survive and thrive at room temperature which ranges from and to .
Freshwater pond fish
Three-spined stickleback
Nine-spined stickleback
Common goldfish
Comet goldfish
Shubunkin
Sterlet
Koi
Golden orfe
Blue orfe
Bitterling
Gobio
Grass carp
Albino grass carp
Fathead minnow
Rosy red minnow
Mirror carp
Common carp
Golden rudd
Green tench
Golden tench
Channel catfish
Golden rainbow trout
Roach
Bluegill
Pumpkinseed
Weather loach
Stone loach
Spined loach
Common minnow
Saltwater aquarium fish
Garibaldi
Catalina goby
Zebra Catalina goby (Lythrypnus zebra)
Ornate boxfish
Shaw's boxfish
White bar boxfish
Truncate coralfish
Blue devil
Pot bellied seahorses | Coldwater fish | Wikipedia | 453 | 2943192 | https://en.wikipedia.org/wiki/Coldwater%20fish | Biology and health sciences | Fishes by habitat | Animals |
Wild fisheries
The term "coldwater" is also used to refer to wild fish species that prefer bodies of water that are colder than most temperate waters. In recreational fishing, anglers may loosely break down fish into categories of warm-water fish, cool-water fish, and cold-water fish. Warm-water fish, such as largemouth bass, sunfish and bullhead catfish, are species that tend to dwell in relatively warm tropical and temperate waters similar to the room temperatures that humans easily find comfortable. Cool-water species, such as smallmouth bass and walleye, can tolerate a wide range of temperatures, but tend to be most abundant in cooler rivers or deeper parts of ponds and lakes, where the temperature is slightly lower than room temperatures. Cold-water species, such as salmonids (e.g. salmon, trout, char, graylings, freshwater whitefishes, etc.) and gadiforms (cods, hakes, pollock, haddock, burbot and rocklings, etc.), however become stressed at warm temperatures and are most active in colder temperatures around which resemble a more subarctic or alpine condition. Because these designations are informal, different fisheries management authorities may recognize different boundaries in temperature preference between the categories. | Coldwater fish | Wikipedia | 255 | 2943192 | https://en.wikipedia.org/wiki/Coldwater%20fish | Biology and health sciences | Fishes by habitat | Animals |
Antibiotic sensitivity testing or antibiotic susceptibility testing is the measurement of the susceptibility of bacteria to antibiotics. It is used because bacteria may have resistance to some antibiotics. Sensitivity testing results can allow a clinician to change the choice of antibiotics from empiric therapy, which is when an antibiotic is selected based on clinical suspicion about the site of an infection and common causative bacteria, to directed therapy, in which the choice of antibiotic is based on knowledge of the organism and its sensitivities.
Sensitivity testing usually occurs in a medical laboratory, and uses culture methods that expose bacteria to antibiotics, or genetic methods that test to see if bacteria have genes that confer resistance. Culture methods often involve measuring the diameter of areas without bacterial growth, called zones of inhibition, around paper discs containing antibiotics on agar culture dishes that have been evenly inoculated with bacteria. The minimum inhibitory concentration, which is the lowest concentration of the antibiotic that stops the growth of bacteria, can be estimated from the size of the zone of inhibition.
Antibiotic susceptibility testing has been needed since the discovery of the beta-lactam antibiotic penicillin. Initial methods were phenotypic, and involved culture or dilution. The Etest, an antibiotic impregnated strip, has been available since the 1980s, and genetic methods such as polymerase chain reaction (PCR) testing have been available since the early 2000s. Research is ongoing into improving current methods by making them faster or more accurate, as well as developing new methods for testing, such as microfluidics. | Antibiotic sensitivity testing | Wikipedia | 327 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Uses
In clinical medicine, antibiotics are most frequently prescribed on the basis of a person's symptoms and medical guidelines. This method of antibiotic selection is called empiric therapy, and it is based on knowledge about what bacteria cause an infection, and to what antibiotics bacteria may be sensitive or resistant. For example, a simple urinary tract infection might be treated with trimethoprim/sulfamethoxazole. This is because Escherichia coli is the most likely causative bacterium, and may be sensitive to that combination antibiotic. However, bacteria can be resistant to several classes of antibiotics. This resistance might be because a type of bacteria has intrinsic resistance to some antibiotics, because of resistance following past exposure to antibiotics, or because resistance may be transmitted from other sources such as plasmids. Antibiotic sensitivity testing provides information about which antibiotics are more likely to be successful and should therefore be used to treat the infection.
Antibiotic sensitivity testing is also conducted at a population level in some countries as a form of screening. This is to assess the background rates of resistance to antibiotics (for example with methicillin-resistant Staphylococcus aureus), and may influence guidelines and public health measures.
Methods
Once a bacterium has been identified following microbiological culture, antibiotics are selected for susceptibility testing. Susceptibility testing methods are based on exposing bacteria to antibiotics and observing the effect on the growth of the bacteria (phenotypic testing), or identifying specific genetic markers (genetic testing). Methods used may be qualitative, meaning that a result indicates resistance is or is not present; or quantitative, using a minimum inhibitory concentration (MIC) to describe the concentration of antibiotic to which a bacterium is sensitive.
There are many factors that can affect the results of antibiotic sensitivity testing, including failure of the instrument, temperature, moisture, and potency of the antimicrobial agent. Quality control (QC) testing helps to ensure the accuracy of test results. Organizations such as the American Type Culture Collection and National Collection of Type Cultures provide strains of bacteria with known resistance phenotypes that can be used for quality control.
Phenotypic methods | Antibiotic sensitivity testing | Wikipedia | 448 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Testing based on exposing bacteria to antibiotics uses agar plates or dilution in agar or broth. The selection of antibiotics will depend on the organism grown, and the antibiotics that are available locally. To ensure that the results are accurate, the concentration of bacteria that is added to the agar or broth (the inoculum) must be standardized. This is accomplished by comparing the turbidity of bacteria suspended in saline or broth to McFarland standards—solutions whose turbidity is equivalent to that of a suspension containing a given concentration of bacteria. Once an appropriate concentration (most commonly an 0.5 McFarland standard) has been reached, which can be determined by visual inspection or by photometry, the inoculum is added to the growth medium.
Manual
The disc diffusion method involves selecting a strain of bacteria, placing it on an agar plate, and observing bacterial growth near antibiotic-impregnated discs. This is also called the Kirby-Bauer method, although modified methods are also used. In some cases, urine samples or positive blood culture samples are applied directly to the test medium, bypassing the preliminary step of isolating the organism. If the antibiotic inhibits microbial growth, a clear ring, or zone of inhibition, is seen around the disc. The bacteria are classified as sensitive, intermediate, or resistant to an antibiotic by comparing the diameter of the zone of inhibition to defined thresholds which correlate with MICs.
Mueller–Hinton agar is frequently used in the disc diffusion test. The Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) provide standards for the type and depth of agar, temperature of incubation, and method of analysing results. Disc diffusion is considered the cheapest and most simple of the methods used to test for susceptibility, and is easily adapted to testing newly available antibiotics or formulations. Some slow-growing and fastidious bacteria cannot be accurately tested by this method, while others, such as Streptococcus species and Haemophilus influenzae, can be tested but require specialized growth media and incubation conditions. | Antibiotic sensitivity testing | Wikipedia | 454 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Gradient methods, such as Etest, use a plastic strip placed on agar. A plastic strip impregnated with different concentrations of antibiotics is placed on a growth medium, and the growth medium is viewed after a period of incubation. The minimum inhibitory concentration can be identified based on the intersection of the teardrop-shaped zone of inhibition with the marking on the strip. Multiple strips for different antibiotics may be used. This type of test is considered a diffusion test.
In agar and broth dilution methods, bacteria are placed in multiple small tubes with different concentrations of antibiotics. Whether a bacterium is sensitive or not is determined by visual inspection or automatic optical methods, after a period of incubation. Broth dilution is considered the gold standard for phenotypic testing. The lowest concentration of antibiotics that inhibits growth is considered the MIC.
Automated
Automated systems exist that replicate manual processes, for example, by using imaging and software analysis to report the zone of inhibition in diffusion testing, or dispensing samples and determining results in dilutional testing. Automated instruments, such as the VITEK 2, BD Phoenix, and Microscan systems, are the most common methodology for AST. The specifications of each instrument vary, but the basic principle involves the introduction of a bacterial suspension into pre-formulated panels of antibiotics. The panels are incubated and the inhibition of bacterial growth by the antibiotic is automatically measured using methodologies such as turbidimetry, spectrophotometry or fluorescence detection. An expert system correlates the MICs with susceptibility results, and the results are automatically transmitted into the laboratory information system for validation and reporting. While such automated testing is less labour-intensive and more standardized than manual testing, its accuracy can be comparatively poor for certain organisms and antibiotics, so the disc diffusion test remains useful as a backup method. | Antibiotic sensitivity testing | Wikipedia | 382 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Genetic methods
Genetic testing, such as via polymerase chain reaction (PCR), DNA microarray, and loop-mediated isothermal amplification, may be used to detect whether bacteria possess genes which confer antibiotic resistance. An example is the use of PCR to detect the mecA gene for beta-lactam resistant Staphylococcus aureus. Other examples include assays for testing vancomycin resistance genes vanA and vanB in Enterococcus species, and antibiotic resistance in Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli. These tests have the benefit of being direct and rapid, as compared with observable methods, and have a high likelihood of detecting a finding when there is one to detect. However, whether resistance genes are detected does not always match the resistance profile seen with phenotypic method. The tests are also expensive and require specifically trained personnel.
Polymerase chain reaction is a method of identifying genes related to antibiotic susceptibility. In the PCR process, a bacterium's DNA is denatured and the two strands of the double helix separate. Primers specific to a sought-after gene are added to a solution containing the DNA, and a DNA polymerase is added alongside a mixture containing molecules that will be needed (for example, nucleotides and ions). If the relevant gene is present, every time this process runs, the quantity of the target gene will be doubled. After this process, the presence of the genes is demonstrated through a variety of methods including electrophoresis, southern blotting, and other DNA sequencing analysis methods.
DNA microarrays and chips use the binding of complementary DNA to a target gene or nucleic acid sequence. The benefit of this is that multiple genes can be assessed simultaneously.
Using magnetic nanoparticles studded with a beta-2-glycoprotein I peptide imitating a plasma protein, microbial pathogens could selectively be retrieved from blood culture specimens within hours, in a study published September 2024. Magnets are used to fish out the peptide-bacterial complex, followed by genetic testing. | Antibiotic sensitivity testing | Wikipedia | 446 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
MALDI-TOF
Matrix-assisted laser desorption ionisation-time of flight mass spectrometry (MALDI-TOF MS) is another method of susceptibility testing. This is a form of time-of-flight mass spectrometry, in which the molecules of a bacterium are subject to matrix-assisted laser desorption. The ionised particles are then accelerated, and spectral peaks recorded, producing an expression profile, which is capable of differentiating specific bacterial strains after being compared to known profiles. This includes, in the context of antibiotic susceptibility testing, strains such as beta-lactamase producing E. coli. MALDI-TOF is rapid and automated. There are limitations to testing in this format however; results may not match the results of phenotypic testing, and acquisition and maintenance is expensive.
Reporting
Bacteria are marked as sensitive, resistant, or having intermediate resistance to an antibiotic based on the minimum inhibitory concentration (MIC), which is the lowest concentration of the antibiotic that stops the growth of bacteria. The MIC is compared to standard threshold values (called "breakpoints") for a given bacterium and antibiotic. Breakpoints for the same organism and antibiotic may differ based on the site of infection: for example, the CLSI generally defines Streptococcus pneumoniae as sensitive to intravenous penicillin if MICs are ≤0.06 μg/ml, intermediate if MICs are 0.12 to 1 μg/ml, and resistant if MICs are ≥2 μg/ml, but for cases of meningitis, the breakpoints are considerably lower. Sometimes, whether an antibiotic is marked as resistant is also based on bacterial characteristics that are associated with known methods of resistance such as the potential for beta-lactamase production. Specific patterns of drug resistance or multidrug resistance may be noted, such as the presence of an extended-spectrum beta lactamase. Such information may be useful to the clinician, who can change the empiric treatment to a tailored treatment that is directed only at the causative bacterium. The results of antimicrobial susceptibility tests performed during a given time period can be compiled, usually in the form of a table, to form an antibiogram. Antibiograms help the clinician to select the best empiric antimicrobial therapy based on the local resistance patterns until the laboratory test results are available.
Clinical practice | Antibiotic sensitivity testing | Wikipedia | 511 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Ideal antibiotic therapy is based on determining the causal agent and its antibiotic sensitivity. Empiric treatment is often started before laboratory microbiological reports are available. This might be for common or relatively minor infections based on clinical guidelines (such as community-acquired pneumonia), or for serious infections, such as sepsis or bacterial meningitis, in which delayed treatment carries substantial risks. The effectiveness of individual antibiotics varies with the anatomical site of the infection, the ability of the antibiotic to reach the site of infection, and the ability of the bacteria to resist or inactivate the antibiotic.
Specimens for antibiotic sensitivity testing are ideally collected before treatment is started. A sample may be taken from the site of a suspected infection; such as a blood culture sample when bacteria are suspected to be present in the bloodstream (bacteraemia), a sputum sample in the case of a pneumonia, or a urine sample in the case of a urinary tract infection. Sometimes multiple samples may be taken if the source of an infection is not clear. These samples are transferred to the microbiology laboratory where they are added to culture media, in or on which the bacteria grow until they are present in sufficient quantities for identification and sensitivity testing to be carried out.
When antibiotic sensitivity testing is completed, it will report the organisms present in the sample, and which antibiotics they are susceptible to. Although antibiotic sensitivity testing is done in a laboratory (in vitro), the information provided about this is often clinically relevant to the antibiotics in a person (in vivo). Sometimes, a decision must be made for some bacteria as to whether they are the cause of an infection, or simply commensal bacteria or contaminants, such as Staphylococcus epidermidis and other opportunistic infections. Other considerations may influence the choice of antibiotics, including the need to penetrate through to an infected site (such as an abscess), or the suspicion that one or more causes of an infection were not detected in a sample.
History
Since the discovery of the beta-lactam antibiotic penicillin, the rates of antimicrobial resistance have increased. Over time, methods for testing the sensitivity of bacteria to antibiotics have developed and changed. | Antibiotic sensitivity testing | Wikipedia | 460 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
Alexander Fleming in the 1920s developed the first method of susceptibility testing. The "gutter method" that he developed was a diffusion method, involving an antibiotic that was diffused through a gutter made of agar. In the 1940s, multiple investigators, including Pope, Foster and Woodruff, Vincent and Vincent used paper discs instead. All these methods involve testing only susceptibility to penicillin. The results were difficult to interpret and not reliable, because of inaccurate results that were not standardised between laboratories.
Dilution has been used as a method to grow and identify bacteria since the 1870s, and as a method of testing the susceptibility of bacteria to antibiotics since 1929, also by Alexander Fleming. The way of determining susceptibility changed from how turbid the solution was, to the pH (in 1942), to optical instruments. The use of larger tube-based "macrodilution" testing has been superseded by smaller "microdilution" kits.
In 1966, the World Health Organisation confirmed the Kirby–Bauer method as the standard method for susceptibility testing; it is simple, cost-effective and can test multiple antibiotics.
The Etest was developed in 1980 by Bolmstrӧm and Eriksson, and MALDI-TOF developed in 2000s. An array of automated systems has been developed since and after the 1980s. PCR was the first genetic test available and first published as a method of detecting antibiotic susceptibility in 2001.
Further research
Point-of-care testing is being developed to speed up the time for testing, and to help practitioners avoid prescribing unnecessary antibiotics in the style of precision medicine. Traditional techniques typically take between 12 and 48 hours, although it can take up to five days. In contrast, rapid testing using molecular diagnostics is defined as "being feasible within an 8-h(our) working shift". Progress has been slow due to a range of reasons including cost and regulation.
Additional research is focused at the shortcomings of current testing methods. As well as the duration it takes to report phenotypic methods, they are laborious, have difficult portability and are difficult to use in resource-limited settings, and have a chance of cross-contamination. | Antibiotic sensitivity testing | Wikipedia | 463 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
As of 2017, point-of-care resistance diagnostics were available for methicillin-resistant Staphylococcus aureus (MRSA), rifampin-resistant Mycobacterium tuberculosis (TB), and vancomycin-resistant enterococci (VRE) through GeneXpert by molecular diagnostics company Cepheid.
Quantitative PCR, with the view of determining the percent of a detected bacteria that possesses a resistance gene, is being explored. Whole genome sequencing of isolated bacteria is also being explored, and likely to become more available as costs decrease and speed increases over time.
Additional methods explored include microfluidics, which uses a small amount of fluid and a variety of testing methods, such as optical, electrochemical, and magnetic. Such assays do not require much fluid to be tested, are rapid and portable.
The use of fluorescent dyes has been explored. These involve labelled proteins targeted at biomarkers, nucleic acid sequences present within cells that are found when the bacterium is resistant to an antibiotic. An isolate of bacteria is fixed in position and then dissolved. The isolate is then exposed to fluorescent dye, which will be luminescent when viewed.
Improvements to existing platforms are also being explored, including improvements in imaging systems that are able to more rapidly identify the MIC in phenotypic samples; or the use of bioluminescent enzymes that reveal bacterial growth to make changes more easily visible.
Bibliography | Antibiotic sensitivity testing | Wikipedia | 299 | 2943640 | https://en.wikipedia.org/wiki/Antibiotic%20sensitivity%20testing | Biology and health sciences | Basics_3 | Biology |
A pregnancy test is used to determine whether a female is pregnant or not. The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. Testing blood for hCG results in the earliest detection of pregnancy. Almost all pregnant women will have a positive urine pregnancy test one week after the first day of a missed menstrual period.
Types
Human chorionic gonadotropin (hCG)
Identified in the early 20th century, human chorionic gonadotropin (hCG) is a glycoprotein hormone that rises quickly in the first few weeks of pregnancy, typically reaching a peak at 8- to 10-weeks gestational age. hCG is produced by what will become the placenta. hCG testing can be performed with a blood (serum) sample (typically done in a medical facility) or with urine (which can be performed in a medical facility or at home). The assays used to detect the presence of hCG in blood or urine are generally reliable and inexpensive. Secretion of hCG can occur as soon as 6 days following ovulation and on average 8–10 days following ovulation; this is the earliest hCG can be detected in a blood sample. The hCG concentration in blood is higher than in urine. Therefore, a blood test can be positive while the urine test is still negative.
Qualitative tests (yes/no or positive/negative results) look for the presence of the beta subunit of human chorionic gonadotropin in blood or urine. For a qualitative test the thresholds for a positive test are generally determined by an hCG cut-off where at least 95% of pregnant women would get a positive result on the day of their first missed period. Qualitative urine pregnancy tests vary in sensitivity. High-sensitivity tests are more common and typically detect hCG levels between 20 and 50 milli-international units/mL (mIU/mL). Low-sensitivity tests detect hCG levels between 1500 and 2000 mIU/mL and have unique clinical applications, including confirmation of medication abortion success. Qualitative urine tests available for home use are typically designed as lateral flow tests. | Pregnancy test | Wikipedia | 476 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
Quantitative tests measure the exact amount of hCG in the sample. Blood tests can detect hCG levels as low as 1 mIU/mL, and typically clinicians will diagnose a positive pregnancy test at 5mIU/mL.
There is a multilevel urine pregnancy test (MLPT) that measures hCG levels semiquantitatively. The hCG levels are measured at <25, 25 to 99, 100 to 499, 500 to 1999, 2000 to 9999, and >10,000 mIU/mL. This test has utility for determining the success of medication abortion.
Ultrasound
Obstetric ultrasonography may also be used to detect and diagnose pregnancy. It is very common to have a positive at-home urine pregnancy test before an ultrasound. Both abdominal and vaginal ultrasound may be used, but vaginal ultrasound allows for earlier visualization of the pregnancy. With obstetric ultrasonography the gestational sac (intrauterine fluid collection) can be visualized at 4.5 to 5 weeks gestation, the yolk sac at 5 to 6 weeks gestation, and fetal pole at 5.5 to 6 weeks gestation. Ultrasound is used to diagnose multiple gestation, which cannot be diagnosed based on the presence of hCG in urine or blood. Determination of the gestational age of the embryo/fetus is an additional benefit of ultrasound compared to hCG tests.
Accuracy
A systematic review published in 1998 showed that home pregnancy test kits, when used by experienced technicians, are almost as accurate as professional laboratory testing (97.4%). When used by consumers, however, the accuracy fell to 75%: the review authors noted that many users misunderstood or failed to follow the instructions included in the kits.
False positive
False positive pregnancy test results are rare and may occur for several reasons, including:
user error in performing and interpreting the test,
biochemical pregnancy (loss of pregnancy before signs of pregnancy are apparent on ultrasound, likely very soon after implantation),
and non-pregnant production of the hCG molecule (i.e. secretion due to a tumor or the pituitary gland, some diseases of the liver, cancers, including choriocarcinoma and other germ cell tumors, IgA deficiencies, heterophile antibodies, enterocystoplasties, gestational trophoblastic diseases (GTD), and gestational trophoblastic neoplasms).
bacterial contamination and blood in urine | Pregnancy test | Wikipedia | 512 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
Spurious evaporation lines may appear on many home pregnancy tests if read after the suggested 3–5 minute window or reaction time, independent of an actual pregnancy. False positives may also appear on tests used past their expiration date.
False positive pregnancy test can happen due to 'phantom hCG' which is due to people having human antianimal or heterophilic antibodies.
False positives can also be caused by (in order of incidence) quiescent pregnancy, pituitary sulfated hCG, heterophilic antibody, familial hCG syndrome and cancer.
Due to use of medication
Urine tests can be falsely positive in those that are taking the medications: chlorpromazine, promethazine, phenothiazines, methadone, aspirin, carbamazepine and drugs that cause high urinary pH.
False negative
False negative readings can occur when testing is done too early. hCG levels rise rapidly in early pregnancy and the chances of false negative test results diminish with time (increasing gestational age). Less sensitive urine tests and qualitative blood tests may not detect pregnancy until three or four days after implantation. Menstruation occurs on average 14 days after ovulation, so the likelihood of a false negative is low once a menstrual period is late. Ovulation may not occur at a predictable time in the menstrual cycle. A number of factors may cause an unexpectedly early or late ovulation, even for people with a history of regular menstrual cycles. Medical providers often struggle to 'rule out' pregnancy for medical testing or treatment that cannot be conducted during pregnancy before they can do an accurate urine pregnancy test.
More rare, false negative results can also occur due to a "hook effect", where a sample with a very high level of hCG is tested without dilution, causing an invalid result. | Pregnancy test | Wikipedia | 396 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
Other uses
Pregnancy tests may be used to predict if a pregnancy is likely to continue or is abnormal. Miscarriage, or spontaneous abortion or pregnancy loss, is common in early pregnancy. Serial quantitative blood tests may be done, usually 48 hours apart, and interpreted based on the knowledge that hCG in a viable normal pregnancy rises rapidly in early pregnancy. For example, for a starting hCG level of 1,500 mIU/ml or less, the hCG of continuing, normal pregnancy will increase at least 49% in 48 hours. However, for pregnancies with a higher starting hCG, between 1,500 and 3,000 mIU/ml, the hCG should rise at least 40%; for a starting hCG greater than 3,000 mIU/ml, the hCG should increase at least 33%. Failure to rise by these minimums may indicate that the pregnancy is not normal, either as a failed intrauterine pregnancy or a possible ectopic pregnancy.
Ultrasound is also a common tool for determining viability and location of a pregnancy. Serial ultrasound may be used to identify non-viable pregnancies, as pregnancies that do not grow in size or develop expected structural findings on repeated ultrasounds over a 1–2 week interval may be identified as abnormal. Occasionally, a single ultrasound may be used to identify a pregnancy as non-viable; for example, an embryo that is greater than a certain size but that lacks a visible heart beat may be confidently determined to be not viable without the need for follow up ultrasound for confirmation.
Research
Research has identified at least one other possible marker that may appear earlier and exclusively during pregnancy. For example, early pregnancy factor (EPF) can be detected in blood within 48 hours of fertilization, rather than after implantation. However, its reliable use as a pregnancy test remains unclear as studies have shown its presence in physiological situations besides pregnancy, and its application to humans remains limited.
History | Pregnancy test | Wikipedia | 396 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
Records of attempts at pregnancy testing have been found as far back as the ancient Greek and ancient Egyptian cultures. The ancient Egyptians watered bags of wheat and barley with the urine of a possibly pregnant woman. Germination indicated pregnancy. The type of grain that sprouted was taken as an indicator of the fetus's sex. Hippocrates suggested that a woman who had missed her period should drink a solution of honey in water at bedtime: resulting abdominal distention and cramps would indicate the presence of a pregnancy. Avicenna and many physicians after him in the Middle Ages performed uroscopy, a nonscientific method to evaluate urine.
Selmar Aschheim and Bernhard Zondek introduced testing based on the presence of human chorionic gonadotropin (hCG) in 1928. Early studies of hCG had concluded that it was produced by the pituitary gland. In the 1930s, Doctor Georgeanna Jones discovered that hCG was produced not by the pituitary gland, but by the placenta. This discovery was important in relying on hCG as an early marker of pregnancy. In the Aschheim and Zondek test, an infantile female mouse was injected subcutaneously with urine of the woman to be tested, and the mouse later was killed and dissected. Presence of ovulation indicated that the urine contained hCG and meant that the subject was pregnant. A similar test was developed using immature rabbits. Here, too, killing the animal to check her ovaries was necessary.
At the beginning of the 1930s, Hillel Shapiro and Harry Zwarenstein, who were researchers at the University of Cape Town, discovered that if urine from a pregnant woman was injected into the South African Xenopus frog and the frog ovulated, this indicated that the subject was pregnant. This test, known as the frog test, was used throughout the world from the 1930s to 1960s, with Xenopus frogs being exported in great numbers. Shapiro's advisor, Lancelot Hogben, claimed to have developed the pregnancy test himself, but this was refuted by both Shapiro and Zwarenstein in a letter to the British Medical Journal. A later article, independently authored, granted Hogben credit for the principle of using Xenopus to determine gonadotropin levels in a pregnant woman's urine, but not for its usage as a functional pregnancy test. | Pregnancy test | Wikipedia | 492 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
Hormonal pregnancy tests such as Primodos and Duogynon were used in the 1960s and 1970s in the UK and Germany. These tests involved taking a dosed amount of hormones, and observing the response a few days later. A pregnant woman does not react, as she is producing the hormones in pregnancy; a subject who is not pregnant responds to the absence of the hormone by beginning a new menstrual cycle. While the test was (is) generally considered accurate, research advancements have replaced it with simpler techniques.
Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing and initiated a series of improvements in pregnancy testing leading to the contemporary at-home testing. Direct measurement of antigens, such as hCG, was made possible after the invention of the radioimmunoassay in 1959. Radioimmunoassays require sophisticated apparatus and special radiation precautions and are expensive.
Organon International obtained the first patent on a home pregnancy test in 1969, two years after product designer Margaret Crane noticed that the laboratory testing procedure was relatively simple and made a prototype. The product became available in Canada in 1971, and the United States in 1977, after delays caused by concerns over sexual morality and the ability of potentially pregnant women to perform the test and cope with the results without a doctor.
Another home pregnancy testing kit was based on the work of Judith Vaitukaitis and Glenn Braunstein, who developed a sensitive hCG assay at the National Institutes of Health. That test went onto the market in 1978.
In the 1970s, the discovery of monoclonal antibodies led to the development of the relatively simple and cheap immunoassays, such as agglutination-inhibition-based assays and sandwich ELISA, used in modern home pregnancy tests. Tests are now so cheap that they can be mass-produced in a general publication and used for advertising. | Pregnancy test | Wikipedia | 408 | 311410 | https://en.wikipedia.org/wiki/Pregnancy%20test | Biology and health sciences | Diagnostics | Health |
A mammary gland is an exocrine gland in humans and other mammals that produces milk to feed young offspring. Mammals get their name from the Latin word mamma, "breast". The mammary glands are arranged in organs such as the breasts in primates (for example, humans and chimpanzees), the udder in ruminants (for example, cows, goats, sheep, and deer), and the dugs of other animals (for example, dogs and cats). Lactorrhea, the occasional production of milk by the glands, can occur in any mammal, but in most mammals, lactation, the production of enough milk for nursing, occurs only in phenotypic females who have gestated in recent months or years. It is directed by hormonal guidance from sex steroids. In a few mammalian species, male lactation can occur. With humans, male lactation can occur only under specific circumstances.
Mammals are divided into 3 groups: prototherians, metatherians, and eutherians. In the case of prototherians, both males and females have functional mammary glands, but their mammary glands are without nipples. These mammary glands are modified sebaceous glands. Concerning most metatherians and eutherians, only females have functional mammary glands, with the exception of some bat species. Their mammary glands can be termed as breasts or udders. In the case of breasts, each mammary gland has its own nipple (e.g., human mammary glands). In the case of udders, pairs of mammary glands comprise a single mass, with more than one nipple (or teat) hanging from it. For instance, cows and buffalo udders have two pairs of mammary glands and four teats, whereas sheep and goat udders have one pair of mammary glands with two teats protruding from the udder. Each gland produces milk for a single teat. These mammary glands are evolutionarily derived from sweat glands.
Structure | Mammary gland | Wikipedia | 430 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
The basic components of a mature mammary gland are the alveoli (hollow cavities, a few millimeters large), which are lined with milk-secreting cuboidal cells and surrounded by myoepithelial cells. These alveoli join to form groups known as lobules. Each lobule has a lactiferous duct that drains into openings in the nipple. The myoepithelial cells contract under the stimulation of oxytocin, excreting the milk secreted by alveolar units into the lobule lumen toward the nipple. As the infant begins to suck, the oxytocin-mediated "let down reflex" ensues, and the mother's milk is secreted—not sucked—from the gland into the infant's mouth.
All the milk-secreting tissue leading to a single lactiferous duct is collectively called a "simple mammary gland"; in a "complex mammary gland", all the simple mammary glands serve one nipple. Humans normally have two complex mammary glands, one in each breast, and each complex mammary gland consists of 10–20 simple glands. The opening of each simple gland on the surface of the nipple is called a "pore." The presence of more than two nipples is known as polythelia and the presence of more than two complex mammary glands as polymastia.
Maintaining the correct polarized morphology of the lactiferous duct tree requires another essential component – mammary epithelial cells extracellular matrix (ECM) which, together with adipocytes, fibroblast, inflammatory cells, and others, constitute mammary stroma. Mammary epithelial ECM mainly contains myoepithelial basement membrane and the connective tissue. They not only help to support mammary basic structure, but also serve as a communicating bridge between mammary epithelia and their local and global environment throughout this organ's development.
Histology
A mammary gland is a specific type of apocrine gland specialized for manufacture of colostrum (first milk) when giving birth. Mammary glands can be identified as apocrine because they exhibit striking "decapitation" secretion. Many sources assert that mammary glands are modified sweat glands.
Development | Mammary gland | Wikipedia | 488 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
Mammary glands develop during different growth cycles. They exist in both sexes during the embryonic stage, forming only a rudimentary duct tree at birth. In this stage, mammary gland development depends on systemic (and maternal) hormones, but is also under the (local) regulation of paracrine communication between neighboring epithelial and mesenchymal cells by parathyroid hormone-related protein (PTHrP). This locally secreted factor gives rise to a series of outside-in and inside-out positive feedback between these two types of cells, so that mammary bud epithelial cells can proliferate and sprout down into the mesenchymal layer until they reach the fat pad to begin the first round of branching. At the same time, the embryonic mesenchymal cells around the epithelial bud receive secreting factors activated by PTHrP, such as BMP4. These mesenchymal cells can transform into a dense, mammary-specific mesenchyme, which later develop into connective tissue with fibrous threads, forming blood vessels and the lymph system. A basement membrane, mainly containing laminin and collagen, formed afterward by differentiated myoepithelial cells, keeps the polarity of this primary duct tree. These components of the extracellular matrix are strong determinants of duct morphogenesis. | Mammary gland | Wikipedia | 290 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
Biochemistry
Estrogen and growth hormone (GH) are essential for the ductal component of mammary gland development, and act synergistically to mediate it. Neither estrogen nor GH are capable of inducing ductal development without the other. The role of GH in ductal development has been found to be mostly mediated by its induction of the secretion of insulin-like growth factor 1 (IGF-1), which occurs both systemically (mainly originating from the liver) and locally in the mammary fat pad through activation of the growth hormone receptor (GHR). However, GH itself also acts independently of IGF-1 to stimulate ductal development by upregulating estrogen receptor (ER) expression in mammary gland tissue, which is a downstream effect of mammary gland GHR activation. In any case, unlike IGF-1, GH itself is not essential for mammary gland development, and IGF-1 in conjunction with estrogen can induce normal mammary gland development without the presence of GH. In addition to IGF-1, other paracrine growth factors such as epidermal growth factor (EGF), transforming growth factor beta (TGF-β), amphiregulin, fibroblast growth factor (FGF), and hepatocyte growth factor (HGF) are involved in breast development as mediators downstream to sex hormones and GH/IGF-1.
During embryonic development, IGF-1 levels are low, and gradually increase from birth to puberty. At puberty, the levels of GH and IGF-1 reach their highest levels in life and estrogen begins to be secreted in high amounts in females, which is when ductal development mostly takes place. Under the influence of estrogen, stromal and fat tissue surrounding the ductal system in the mammary glands also grows. After puberty, GH and IGF-1 levels progressively decrease, which limits further development until pregnancy, if it occurs. During pregnancy, progesterone and prolactin are essential for mediating lobuloalveolar development in estrogen-primed mammary gland tissue, which occurs in preparation of lactation and nursing. | Mammary gland | Wikipedia | 472 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
Androgens such as testosterone inhibit estrogen-mediated mammary gland development (e.g., by reducing local ER expression) through activation of androgen receptors expressed in mammary gland tissue, and in conjunction with relatively low estrogen levels, are the cause of the lack of developed mammary glands in males.
Timeline
Before birth
Mammary gland development is characterized by the unique process by which the epithelium invades the stroma. The development of the mammary gland occurs mainly after birth. During puberty, tubule formation is coupled with branching morphogenesis which establishes the basic arboreal network of ducts emanating from the nipple.
Developmentally, mammary gland epithelium is constantly produced and maintained by rare epithelial cells, dubbed as mammary progenitors which are ultimately thought to be derived from tissue-resident stem cells.
Embryonic mammary gland development can be divided into a series of specific stages. Initially, the formation of the milk lines that run between the fore and hind limbs bilaterally on each side of the midline occurs around embryonic day 10.5 (E10.5). The second stage occurs at E11.5 when placode formation begins along the mammary milk line. This will eventually give rise to the nipple. Lastly, the third stage occurs at E12.5 and involves the invagination of cells within the placode into the mesenchyme, leading to a mammary anlage (biology).
The primitive (stem) cells are detected in embryo and their numbers increase steadily during development
Growth
Postnatally, the mammary ducts elongate into the mammary fat pad. Then, starting around four weeks of age, mammary ductal growth increases significantly with the ducts invading towards the lymph node. Terminal end buds, the highly proliferative structures found at the tips of the invading ducts, expand and increase greatly during this stage. This developmental period is characterized by the emergence of the terminal end buds and lasts until an age of about 7–8 weeks. | Mammary gland | Wikipedia | 439 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
By the pubertal stage, the mammary ducts have invaded to the end of the mammary fat pad. At this point, the terminal end buds become less proliferative and decrease in size. Side branches form from the primary ducts and begin to fill the mammary fat pad. Ductal development decreases with the arrival of sexual maturity and undergoes estrous cycles (proestrus, estrus, metestrus, and diestrus). As a result of estrous cycling, the mammary gland undergoes dynamic changes where cells proliferate and then regress in an ordered fashion.
Pregnancy
During pregnancy, the ductal systems undergo rapid proliferation and form alveolar structures within the branches to be used for milk production. After delivery, lactation occurs within the mammary gland; lactation involves the secretion of milk by the luminal cells in the alveoli. Contraction of the myoepithelial cells surrounding the alveoli will cause the milk to be ejected through the ducts and into the nipple for the nursing infant. Upon weaning of the infant, lactation stops and the mammary gland turns in on itself, a process called involution. This process involves the controlled collapse of mammary epithelial cells where cells begin apoptosis in a controlled manner, reverting the mammary gland back to a pubertal state.
Postmenopausal
During postmenopause, due to much lower levels of estrogen, and due to lower levels of GH and IGF-1, which decrease with age, mammary gland tissue atrophies and the mammary glands become smaller.
Physiology | Mammary gland | Wikipedia | 349 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
Hormonal control
Lactiferous duct development occurs in females in response to circulating hormones. First development is frequently seen during pre- and postnatal stages, and later during puberty. Estrogen promotes branching differentiation, whereas in males testosterone inhibits it. A mature duct tree reaching the limit of the fat pad of the mammary gland comes into being by bifurcation of duct terminal end buds (TEB), secondary branches sprouting from primary ducts and proper duct lumen formation. These processes are tightly modulated by components of mammary epithelial ECM interacting with systemic hormones and local secreting factors. However, for each mechanism the epithelial cells' "niche" can be delicately unique with different membrane receptor profiles and basement membrane thickness from specific branching area to area, so as to regulate cell growth or differentiation sub-locally. Important players include beta-1 integrin, epidermal growth factor receptor (EGFR), laminin-1/5, collagen-IV, matrix metalloproteinase (MMPs), heparan sulfate proteoglycans, and others. Elevated circulating level of growth hormone and estrogen get to multipotent cap cells on TEB tips through a thin, leaky layer of basement membrane. These hormones promote specific gene expression. Hence cap cells can differentiate into myoepithelial and luminal (duct) epithelial cells, and the increased amount of activated MMPs can degrade surrounding ECM helping duct buds to reach further in the fat pads. On the other hand, basement membrane along the mature mammary ducts is thicker, with strong adhesion to epithelial cells via binding to integrin and non-integrin receptors. When side branches develop, it is a much more "pushing-forward" working process including extending through myoepithelial cells, degrading basement membrane and then invading into a periductal layer of fibrous stromal tissue. Degraded basement membrane fragments (laminin-5) roles to lead the way of mammary epithelial cells migration. Whereas, laminin-1 interacts with non-integrin receptor dystroglycan negatively regulates this side branching process in case of cancer. These complex "Yin-yang" balancing crosstalks between mammary ECM and epithelial cells "instruct" healthy mammary gland development until adult. | Mammary gland | Wikipedia | 507 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
There is preliminary evidence that soybean intake mildly stimulates the breast glands in pre- and postmenopausal women.
Pregnancy
Secretory alveoli develop mainly in pregnancy, when rising levels of prolactin, estrogen, and progesterone cause further branching, together with an increase in adipose tissue and a richer blood flow. In gestation, serum progesterone remains at a stably high concentration so signaling through its receptor is continuously activated. As one of the transcribed genes, Wnts secreted from mammary epithelial cells act paracrinely to induce more neighboring cells' branching. When the lactiferous duct tree is almost ready, "leaves" alveoli are differentiated from luminal epithelial cells and added at the end of each branch. In late pregnancy and for the first few days after giving birth, colostrum is secreted. Milk secretion (lactation) begins a few days later due to reduction in circulating progesterone and the presence of another important hormone prolactin, which mediates further alveologenesis, milk protein production, and regulates osmotic balance and tight junction function. Laminin and collagen in myoepithelial basement membrane interacting with beta-1 integrin on epithelial surface again, is essential in this process. Their binding ensures correct placement of prolactin receptors on the basal lateral side of alveoli cells and directional secretion of milk into lactiferous ducts. Suckling of the baby causes release of the hormone oxytocin, which stimulates contraction of the myoepithelial cells. In this combined control from ECM and systemic hormones, milk secretion can be reciprocally amplified so as to provide enough nutrition for the baby. | Mammary gland | Wikipedia | 371 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
Weaning
During weaning, decreased prolactin, missing mechanical stimulation (baby suckling), and changes in osmotic balance caused by milk stasis and leaking of tight junctions cause cessation of milk production. It is the (passive) process of a child or animal ceasing to be dependent on the mother for nourishment. In some species there is complete or partial involution of alveolar structures after weaning, in humans there is only partial involution and the level of involution in humans appears to be highly individual. The glands in the breast do secrete fluid also in nonlactating women. In some other species (such as cows), all alveoli and secretory duct structures collapse by programmed cell death (apoptosis) and autophagy for lack of growth promoting factors either from the ECM or circulating hormones. At the same time, apoptosis of blood capillary endothelial cells speeds up the regression of lactation ductal beds. Shrinkage of the mammary duct tree and ECM remodeling by various proteinase is under the control of somatostatin and other growth inhibiting hormones and local factors. This major structural change leads loose fat tissue to fill the empty space afterward. But a functional lactiferous duct tree can be formed again when a female is pregnant again.
Clinical significance
Tumorigenesis in mammary glands can be induced biochemically by abnormal expression level of circulating hormones or local ECM components, or from a mechanical change in the tension of mammary stroma. Under either of the two circumstances, mammary epithelial cells would grow out of control and eventually result in cancer. Almost all instances of breast cancer originate in the lobules or ducts of the mammary glands.
Other mammals | Mammary gland | Wikipedia | 385 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
General
The breasts of female humans vary from most other mammals that tend to have less conspicuous mammary glands. The number and positioning of mammary glands varies widely in different mammals. The protruding teats and accompanying glands can be located anywhere along the two milk lines. In general most mammals develop mammary glands in pairs along these lines, with a number approximating the number of young typically birthed at a time. The number of teats varies from 2 (in most primates) to 18 (in pigs). The Virginia opossum has 13, one of the few mammals with an odd number. The following table lists the number and position of teats and glands found in a range of mammals:
Male mammals typically have rudimentary mammary glands and nipples, with a few exceptions: male mice do not have nipples, male marsupials do not have mammary glands, and male horses lack nipples. The male dayak fruit bat has lactating mammary glands. Male lactation occurs infrequently in some species.
Mammary glands are true protein factories, and several labs have constructed transgenic animals, mainly goats and cows, to produce proteins for pharmaceutical use. Complex glycoproteins such as monoclonal antibodies or antithrombin cannot be produced by genetically engineered bacteria, and the production in live mammals is much cheaper than the use of mammalian cell cultures.
Evolution
There are many theories on how mammary glands evolved. For example, it is thought that the mammary gland is a transformed sweat gland, more closely related to apocrine sweat glands. Because mammary glands do not fossilize well, supporting such theories with fossil evidence is difficult. Many of the current theories are based on comparisons between lines of living mammals—monotremes, marsupials, and eutherians. One theory proposes that mammary glands evolved from glands that were used to keep the eggs of early mammals moist and free from infection (monotremes still lay eggs). Other theories suggest that early secretions were used directly by hatched young, or that the secretions were used by young to help them orient to their mothers.
Lactation is thought to have developed long before the evolution of the mammary gland and mammals; see evolution of lactation.
Additional images | Mammary gland | Wikipedia | 473 | 311440 | https://en.wikipedia.org/wiki/Mammary%20gland | Biology and health sciences | Integumentary system | Biology |
In mathematics, a function defined on some set with real or complex values is called bounded if the set of its values is bounded. In other words, there exists a real number such that
for all in . A function that is not bounded is said to be unbounded.
If is real-valued and for all in , then the function is said to be bounded (from) above by . If for all in , then the function is said to be bounded (from) below by . A real-valued function is bounded if and only if it is bounded from above and below.
An important special case is a bounded sequence, where is taken to be the set of natural numbers. Thus a sequence is bounded if there exists a real number such that
for every natural number . The set of all bounded sequences forms the sequence space .
The definition of boundedness can be generalized to functions taking values in a more general space by requiring that the image is a bounded set in .
Related notions
Weaker than boundedness is local boundedness. A family of bounded functions may be uniformly bounded.
A bounded operator is not a bounded function in the sense of this page's definition (unless ), but has the weaker property of preserving boundedness; bounded sets are mapped to bounded sets . This definition can be extended to any function if and allow for the concept of a bounded set. Boundedness can also be determined by looking at a graph. | Bounded function | Wikipedia | 285 | 311509 | https://en.wikipedia.org/wiki/Bounded%20function | Mathematics | Functions: General | null |
Examples
The sine function is bounded since for all .
The function , defined for all real except for −1 and 1, is unbounded. As approaches −1 or 1, the values of this function get larger in magnitude. This function can be made bounded if one restricts its domain to be, for example, or .
The function , defined for all real , is bounded, since for all .
The inverse trigonometric function arctangent defined as: or is increasing for all real numbers and bounded with radians
By the boundedness theorem, every continuous function on a closed interval, such as , is bounded. More generally, any continuous function from a compact space into a metric space is bounded.
All complex-valued functions which are entire are either unbounded or constant as a consequence of Liouville's theorem. In particular, the complex must be unbounded since it is entire.
The function which takes the value 0 for rational number and 1 for irrational number (cf. Dirichlet function) is bounded. Thus, a function does not need to be "nice" in order to be bounded. The set of all bounded functions defined on is much larger than the set of continuous functions on that interval. Moreover, continuous functions need not be bounded; for example, the functions and defined by and are both continuous, but neither is bounded. (However, a continuous function must be bounded if its domain is both closed and bounded.) | Bounded function | Wikipedia | 296 | 311509 | https://en.wikipedia.org/wiki/Bounded%20function | Mathematics | Functions: General | null |
Allicin is an organosulfur compound obtained from garlic and leeks. When fresh garlic is chopped or crushed, the enzyme alliinase converts alliin into allicin, which is responsible for the aroma of fresh garlic. Allicin is unstable and quickly changes into a series of other sulfur-containing compounds such as diallyl disulfide. Allicin is an antifeedant, i.e. the defense mechanism against attacks by pests on the garlic plant.
Allicin is an oily, slightly yellow liquid that gives garlic its distinctive odor. It is a thioester of sulfenic acid. It is also known as allyl thiosulfinate. Its biological activity can be attributed to both its antioxidant activity and its reaction with thiol-containing proteins.
Structure and occurrence
Allicin features the thiosulfinate functional group, R-S-(O)-S-R. The compound is not present in garlic unless tissue damage occurs, and is formed by the action of the enzyme alliinase on alliin. Allicin is chiral but occurs naturally only as a racemate. The racemic form can also be generated by oxidation of diallyl disulfide:
(SCH2CH=CH2)2 + 2 RCO3H + H2O → 2 CH2=CHCH2SOH + 2 RCO2H
2 CH2=CHCH2SOH → CH2=CHCH2S(O)SCH2CH=CH2 + H2O
Alliinase is irreversibly deactivated below pH 3; as such, allicin is generally not produced in the body from the consumption of fresh or powdered garlic. Furthermore, allicin can be unstable, breaking down within 16 hours at 23 °C.
Biosynthesis
The biosynthesis of allicin commences with the conversion of cysteine into S-allyl-L-cysteine. Oxidation of this thioether gives the sulfoxide (alliin). The enzyme alliinase, which contains pyridoxal phosphate (PLP), cleaves alliin, generating allylsulfenic acid (CH2=CHCH2SOH), pyruvate, and ammonium ions. At room temperature, two molecules of allylsulfenic acid condense to form allicin. | Allicin | Wikipedia | 511 | 311596 | https://en.wikipedia.org/wiki/Allicin | Physical sciences | Concepts: General | Chemistry |
Research
Allicin has been studied for its potential to treat various kinds of multiple drug resistance bacterial infections, as well as viral and fungal infections in vitro, but as of 2016, the safety and efficacy of allicin to treat infections in people was unclear.
A Cochrane review found there to be insufficient clinical evidence regarding the effects of allicin in preventing or treating common cold.
History
It was first isolated and studied in the laboratory by Chester J. Cavallito and John Hays Bailey in 1944.
Allicin was discovered as part of efforts to create thiamine derivatives in the 1940s, mainly in Japan. Allicin became a model for medicinal chemistry efforts to create other thiamine disulfides. The results included sulbutiamine, fursultiamine (thiamine tetrahydrofurfuryl disulfide) and benfothiamine. These compounds are hydrophobic, easily pass from the intestines to the bloodstream, and are reduced to thiamine by cysteine or glutathione. | Allicin | Wikipedia | 214 | 311596 | https://en.wikipedia.org/wiki/Allicin | Physical sciences | Concepts: General | Chemistry |
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Along with the anterior chamber and lens, the cornea refracts light, accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is approximately 43 dioptres. The cornea can be reshaped by surgical procedures such as LASIK.
While the cornea contributes most of the eye's focusing power, its focus is fixed. Accommodation (the refocusing of light to better view near objects) is accomplished by changing the geometry of the lens. Medical terms related to the cornea often start with the prefix "kerat-" from the Greek word κέρας, horn.
Structure
The cornea has unmyelinated nerve endings sensitive to touch, temperature and chemicals; a touch of the cornea causes an involuntary reflex to close the eyelid. Because transparency is of prime importance, the healthy cornea does not have or need blood vessels within it. Instead, oxygen dissolves in tears and then diffuses throughout the cornea to keep it healthy. Similarly, nutrients are transported via diffusion from the tear fluid through the outside surface and the aqueous humour through the inside surface. Nutrients also come via neurotrophins supplied by the nerves of the cornea. In humans, the cornea has a diameter of about 11.5 mm and a thickness of 0.5–0.6 mm in the center and 0.6–0.8 mm at the periphery. Transparency, avascularity, the presence of immature resident immune cells, and immunologic privilege makes the cornea a very special tissue.
The most abundant soluble protein in mammalian cornea is albumin.
The human cornea borders with the sclera at the corneal limbus. In lampreys, the cornea is solely an extension of the sclera, and is separate from the skin above it, but in more advanced vertebrates it is always fused with the skin to form a single structure, albeit one composed of multiple layers. In fish, and aquatic vertebrates in general, the cornea plays no role in focusing light, since it has virtually the same refractive index as water.
Microanatomy | Cornea | Wikipedia | 473 | 311888 | https://en.wikipedia.org/wiki/Cornea | Biology and health sciences | Visual system | Biology |
The human cornea has five layers (possibly six, if the Dua's layer is included). Corneas of other primates have five known layers. The corneas of cats, dogs, wolves, and other carnivores only have four. From the anterior to posterior the layers of the human cornea are: | Cornea | Wikipedia | 69 | 311888 | https://en.wikipedia.org/wiki/Cornea | Biology and health sciences | Visual system | Biology |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.