Datasets:
xNoper
/
pubmed-sections-test

Dataset card Data Studio Files
xet
 Community
1
article_sections
listlengths
1
17
abstract
stringlengths
18
2.93k
[ "most commonly affects people of african descent . in nigeria , sickle cell anaemia affects about 1 - 3% of the nigerian population . individuals who have only one copy of the mutation are said to have sickle cell trait.12 these people are usually healthy but can transmit the disease to their children.3 sickle cell...
a couple , both carriers of the sickle cell anaemia trait ( genotype hbas ) with an offspring already affected with the genetic disease underwent a pre - implantation genetic diagnosis / polymerase chain reaction screening of biopsied blastomeres . dna analysis of single blastomeres was carried out to find out indicate...
[ "pulse rate , also called heart rate , is the number of heartbeats per unit of time , commonly used as beats per minute ( bpm ) . pulse rate is varied in accordance with the body 's need for oxygen changes , such as during exercise or sleep . since various health - related phenotypes are closely correlated with pul...
pulse rate is known to be related to diverse phenotypes , such as cardiovascular diseases , lifespan , arrhythmia , hypertension , lipids , diabetes , and menopause . we have reported two genomewide significant genetic loci responsible for the variation in pulse rate as a part of the korea association resource ( kare )...
[ "this complication usually occurs during abdominal aortic surgery and is an unusual complication following live donor nephrectomy . live kidney donors are healthy individuals who willingly undergo major surgery to improve the well - being of another individual . therefore , it is of utmost importance to minimize th...
we present the first case report of chylous ascites following total robot - assisted donor nephrectomy . a 39-year - old female underwent a transperitoneal left - sided total robot - assisted donor nephrectomy . the procedure was uneventful and the patient was discharged without any symptoms . at postoperative day 29 ,...
[ "obesity is a worldwide phenomenon , with an incidence increasing in parallel with obesity - associated diseases such as insulin resistance , type 2 diabetes mellitus , and hypertension . the combination of obesity and hypertension places patients at a higher risk of hypertensive end - organ damage and vascular eve...
this study aimed to investigate the effects of gender on the association between epicardial fat thickness ( eft ) and circadian blood pressure ( bp ) changes in patients with recently diagnosed essential hypertension ( eh ) . a total of 441 patients with eh ( male / female : 236/205 , mean age : 50.7 13.8 ) and 83 con...
[ "during the past 2 decades , laparoscopic surgery has gained worldwide popularity resulting from its well - known characteristics of less postoperative pain , fewer complications , earlier discharge , and better cosmesis . smaller skin incisions in laparoscopic surgery were related to fewer unwanted side effects , ...
background and objectives : keyless abdominal rope - lifting surgery is a novel , gasless , single - incision laparoscopic surgical technique . in this study we aimed to compare the postoperative pain from keyless abdominal rope - lifting surgery with carbon dioxide laparoscopy performed for benign ovarian cysts.method...
[ "pancreatitis , the commonest adverse event following endoscopic retrograde cholangiopancreatography ( ercp ) , has been found to occur at widely varying rates , in 1% to 15.1% of pateints.14 post - ercp pancreatitis ( pep ) has been found at lower rates in recent studies because noninvasive methods , such as magne...
backgroundpancreatitis remains the most common complication of endoscopic retrograde cholangiopancreatography ( ercp ) , resulting in substantial morbidity and occasional mortality . there are notable controversies and conflicting reports about risk factors of post - ercp pancreatitis ( pep).aimto evaluate the potentia...
[ "sole aim and the prerequisite for dentistry is an effective pain control during dental procedures . to achieve this goal local anesthesia is being used since long . in 1943 , lofgren synthesized the first modern anaesthesia.1 it is lidocaine , which was an amide derivative of diethyl amino acetic acid . it is beca...
background : articaine in an anesthetic agent , which is used less frequently in dentistry . it differs from other agents due to the presence of a thiophene ring in its molecular structure . few groups of researchers claim that it is superior to lignocaine . hence , the purpose of this study was to compare the efficacy...
[ "the ras association domain family ( rassf ) consists of 10 members : rassf1 - 10 . importantly , all isoforms contain a ras association ( ra ) domain either in their c - terminal ( rassf1 - 6 ) or n - terminal ( rassf7 - 10 ) regions . to date , no known catalytic activity has been described for this family , and ...
the rassf proteins are a family of polypeptides , each containing a conserved ras association domain , suggesting that these scaffold proteins may be effectors of activated ras or ras - related small gtpases . rassf proteins are characterized by their ability to inhibit cell growth and proliferation while promoting cel...
[ "it is one of the most commonly used medicines in the treatment of rheumatoid arthritis or psoriatic arthritis . we report the case of an adult woman with psoriatic arthritis who developed acute severe hepatitis following long - term treatment with mtx .", "the periodic biological monitoring of liver enzymes : al...
methotrexate ( mtx ) is one of the most commonly used medicines in the treatment of psoriatic arthritis . the drug can produce steatosis and cirrhosis . autoimmune hepatitis is a rare and serious adverse effect . we describe the case of a 53-year - old woman who developed autoimmune hepatitis after a long - term use of...
[ "mirizzi syndrome is a rare complication of cholecystolithiasis characterized by jaundice due to compression of the common hepatic duct . the diagnosis may not be immediately apparent , and management is controversial with open surgery still recommended by some authors .", "a case is detailed herein of a 67-year ...
background : mirizzi syndrome is a rare complication of cholecystolithiasis characterized by jaundice due to compression of the common hepatic duct . the diagnosis may not be immediately apparent , and management is controversial with open surgery still recommended by some authors.method:a case is detailed herein of a ...
[ "dirofilaria immitis ( the canine heartworm ) is a filarial nematode naturally hosted by dogs , cats , foxes , muskrat , raccoons , and bears . adult worms live in the right heart of these animals and produce a debilitating disease . this filarial nematode is transmited by mosquitoes . when an infected mosquito tak...
dirofilariasis is a rare disease in humans . we report here a case of a 48-year - old male who was diagnosed with pulmonary dirofilariasis in korea . on chest radiographs , a coin lesion of 1 cm in diameter was shown . although it looked like a benign inflammatory nodule , malignancy could not be excluded . so , the no...
[ "the maxillary posterior area contains cancellous bones with low bone density and thin cortical bones , the quantity and quality of which are lower than those of the mandibular bone . this is due to the small implant - to - bone contact area and the inferior bone quality.123 moreover , the severe bone loss caused b...
purposethe aim of this study was to investigate the stress distribution of 2-short implants ( 2sis ) installed in a severely atrophic maxillary molar site.materials and methodsthree different diameters of internal connection implants were modeled : narrow platform ( np ) , regular platform ( rp ) , and wide platform ( ...
[ "hydatid disease ( echionococcosis ; hydatidosis ) is a parasitic disease , endemic in many sheep raising countries ( australia , south america , mediterranean countries , russia , middle east , and central asia ) . adult cestodes of echinococcus granulosus inhabit the small intestine of a definitive host ( dogs , ...
although serbia is recognized as an endemic country for echinococcosis , no information about precise incidence in humans has been available . the aim of this study was to investigate the skeletal manifestations of hydatid disease in serbia . this retrospective study was conducted by reviewing the medical database of i...
[ "workers ' health may be protected by his / her own preventive behavior , despite numerous health hazards in the workplace . however , worker behavior is constrained by various workplace pressures such as working conditions , including what is considered to be accepted working behavior and overall morale of the wor...
the management system of occupational diseases in korea can be assessed from the perspective of a surveillance system . workers ' compensation insurance reports are used to produce official statistics on occupational diseases in korea . national working conditions surveys are used to monitor the magnitude of work - rel...
[ "a cross - sectional retrospective study was carried out according to world health organization guidelines over 6 months and included 197 general practitioners ( gps ) and 19,700 prescriptions.this study revealed that the overall index of rational drug prescribing ( irdp ) indicator for gps was below the optimal p...
backgroundthe appropriate use of medicines is essential for the provision of quality health services , patient safety , and the rational use of health resources . in sudan , general practitioners ( gps ) provide 80 % of insured patients health services . pharmaceutical service costs have been increasing since 2010.obj...
[ "blunt traumatic infrarenal aortic injuries are rare , with a few case reports in the literature . a more common occurrence is an intimal flap which may form after blunt injury to the aorta , and most of these will resolve with anticoagulation alone [ 1 , 2 ] . blunt aortic injury which initially presents as an int...
blunt traumatic infrarenal aortic injuries are unusual , and the formation of a delayed pseudoaneurysm of the aorta is even more rare . in this report , a young woman developed a small intimal flap of the infrarenal aorta after a motor vehicle accident which progressed into a 3 cm pseudoaneurysm after 3 months . opera...
[ "strains carrying proa - tev - rpt1 were grown in 6 l of sd medium to od600 0.8 to 1.2 . cells were harvested , washed once with ice - cold water and drop - frozen in liquid nitrogen . frozen yeast samples were then ground using an mm301 grinding mill ( restch ) under liquid nitrogen following manufacturer s instru...
substrates of the proteasome are recognized and unfolded by the regulatory particle ( rp ) , then translocated into the core particle ( cp ) to be degraded1 . a hetero - hexameric atpase ring , containing subunits rpt1-rpt6 , is situated within the base subassembly of the rp1 . the atpase ring sits atop the cp , with t...
[ "worldwide , head injury is the single largest cause of death and disability following an injury . the burden of head injury is greatest in low- and middle - income countries ( lamic ) , where 85% of the world 's population live . the world health organization estimates that almost 90% of deaths due to injuries occ...
introduction : it is well - known that severe traumatic brain injuries ( tbi ) have a poor outcome . however , what is not well - known is the outcome for those who survive but remain unconscious at the time of discharge from the hospital.aims and objectives : to assess the outcome of severe tbi patients who have a mot...
[ "their marbling has been increased over many decades to meet domestic consumer preferences . in both countries , highly marbled beef is greatly prized for traditional meat cooking methods such as sukiyaki for japanese and gogigui for korean . because of these demands , the use of heifers and steers instead of bulls...
this review addresses the characteristics and health benefit of highly marbled wagyu and hanwoo beef . marbling of wagyu and hanwoo beef has been increased in japan and korea to meet domestic consumer preferences . wagyu and hanwoo cattle have high potential of accumulating intramuscular fat ( imf ) and producing highl...
[ "\n n - acetyl - l - cysteine ( nac ) is an endogenous aminothiol present both in human plasma and in urine . n-(2-mercaptopropionyl)glycine ( mpg ) , also known as tiopronin , is a synthetic aminothiol antioxidant . nac has been in clinical use for more than 40 years , primarily as a mucolytic agent in a variety o...
a simple spectrophotometric method for the determination of n - acetyl - l - cysteine ( nac ) and n-(2-mercaptopropionyl)glycine ( mpg ) in pharmaceutical preparations was developed , validated , and used . the proposed equilibrium method is based on a coupled two - step redox and complexation reaction . in the fir...
[ "vascular malformation is known as one of the major therapeutic problem even to the most experienced clinicians . these malformations grow proportionately with age , and may involve multiple anatomical spaces and encase critical neuromuscular structures , associated with nerve damage , massive bleeding , and deform...
arteriovenous malformation is treated by variety of techniques over the years . sclerotherapy is considered an effective and conservative technique for the treatment of benign vascular lesions and replaced the traditional role of surgical therapy , especially for the venous lesions that are surgically difficult or at i...
[ "in the 1980s , the prevalence of rickets in extremely low birth weight ( elbw ) infants was around 50% and was 17% for fractures ( 1 , 2 ) . after introduction of a high mineral containing diet in the late 1980s , the prevalence decreased to 30% or lower ( 3 , 4 ) . there is little information , however , beyond 1...
risk factors for rickets of prematurity have not been re - examined since introduction of high mineral formula , particularly in elbw infants . we analyzed the incidence and the risk factors of rickets in extremely low birth weight ( elbw ) infants . as a retrospective case - control study from 2004 to 2008 , risk fact...
[ "kyphosis is a progressive curvature of the thoracic spine , which results in rounding or bowing of the back . a curved spine accompanied by restricted neck motion and poor lung reserve present challenges for an ophthalmic surgeon , who is used to patients neck and head resting flat on the operating table and the e...
we describe a 49-year - old man with advanced kyphosis and dense cataract , who could only recline to about 40 from the vertical axis despite a maximal reverse trendelenburg position and pillows under the head , neck , shoulders and knees . with a single corneal retraction suture at 6 o'clock , the eye could be rotated...
[ "using water as solvent in the organic reactions is one of the most important targets to organic chemists because of the easy availability , nontoxicity , and ecofriendly nature of the water [ 17 ] . in this endeavour , a number of chemical reactions such as diels alder , hetero diels - alder , 1,3-dipolar cycloadd...
a novel catalytic system consisting of i2-sds - h2o has been developed which cleaves 2,3-diaza-1,3-butadiene , 1-aza-1,3-butadienes , oximes and in presence of indoles in the medium uses the corresponding aldehyde products to produce bis(indolyl)alkanes in situ . this one pot simple and mild dual catalytic system works...
[ "parental drug misuse and its effects on children and families are policy priorities in the uk and elsewhere ( flavin & paltrow , 2010 ; hm government , 2010 ) . polydrug use is the norm among drug users in the uk , and benzodiazepine use is common ( bird & robertson , 2011 ; department of health ( england ) , 2007...
aimsto explore the ways in which opioid - dependent parents accounted for their use of opioids and benzodiazepines during and after pregnancy.methodslongitudinal qualitative interviews [ n = 45 ] with 19 opioid - dependent adults recruited in scotland , uk , were held during the antenatal and post - natal period . in...
[ "in industrialized countries , cardiovascular disease ( cvd ) remains the predominant cause of morbidity and mortality . it is current scientific opinion that cvd occurs as a part of a series of events that form a continuum . the first stage of this continuum corresponds to the presence of risks factors that predis...
background . dyslipidemia and diabetes are two of the most well established risk factors for the development of cardiovascular disease ( cvd ) . both of them usually activate a complex range of pathogenic pathways leading to organ damage . here we hypothesized that dyslipidemia and diabetes could affect osteoproteger...
[ "compounds 14 , 7 , 8 , and 11 were \n synthesized following our previously reported synthetic routes . saturated derivatives 5 and 6 , unique to this work , were synthesized via the hydrogenation \n of diastereomers 1 and 2 , respectively . \n palmyrolide alcohol ( 9 ) and acid ( 10 ) were \n prepared exploiting t...
a small library of synthetic ( )-palmyrolide a diastereomers , analogues , and acyclic precursors have been examined with respect to their interaction with voltage - gated sodium channels ( vgscs ) . toward this goal , the ability of ( )-palmyrolide a and analogues to antagonize veratridine - stimulated na+ i...
[ "the online version of this article ( doi:10.1007/s00414 - 009 - 0352 - 9 ) contains supplementary material , which is available to authorized users .", "microbes can negatively interfere with the postmortem assessment of alcohol abuse and in this way pose problems for forensic investigators . however , microbial...
human fingertip microflora is transferred to touched objects and may provide forensically relevant information on individual hosts , such as on geographic origins , if endogenous microbial skin species / strains would be retrievable from physical fingerprints and would carry geographically restricted dna diversity . we...
[ "assisted / supported mechanical ventilation is designed to interact with patient muscle activity and ' share ' the work of breathing . if properly done , assisted / , the ventilatory 's flow and pressure delivery must synchronize with patient effort during all three phases of breath delivery : breath initiation , ...
patient - ventilator trigger dys - synchronies are common with the use of assisted forms of mechanical ventilatory support , including non - invasive mechanical ventilatory support ( niv ) . future system designs need to address this in order to improve the effectiveness of niv .
[ "postanginal septicaemia in the early 20 century ; originally associated with a mortality reaching 90% it involves a classic triad of oropahryngeal sepsis , internal jugular vein ( ijv ) thrombophlebitis and metastatic abscess formation ( 1 ) . clinical findings can therefore vary considerably from neck pain and s...
oropharyngeal infections are routinely encountered within general practice and accident and emergency departments . most settle with simple analgesia and antibiotics ; occasionally such patients may develop lemierre s syndrome ( ls ) a rare and potentially fatal sequela that can be easily overlooked . we aim to highlig...
[ "helicobacter pylori is a gram - negative , spiral and microaerophilic microorganism that was first isolated from the stomach of patients afflicted with peptic ulcer ( 1 , 2 ) . this bacterium can cause gastritis and peptic ulcer in the short - term and carcinoma of the stomach in the long - term ( 3 , 4 ) . polyme...
background : tympanosclerosis is a condition caused by calcification of tissues in the middle ear mucosa that sometimes results hearing loss . helicobacter pylori is one of the pathological and etiologic factors in the development of tympanosclerosis.objectives:the purpose of this study was to show the role of h. pylor...
[ "trigeminal neuralgia ( tn ) is a disorder of cranial nerve ( cn ) v that results in severe episodes of shock - like or lancinating pain in one or more of its three divisions ( v1v3 ) . idiopathic tn and cases due to vascular compression of cn v are categorized as classical tn . patients diagnosed with symptomatic ...
since its introduction by leksell , gamma knife radiosurgery ( gkrs ) has become increasingly popular as a management approach for patients diagnosed with trigeminal neuralgia ( tn ) . for this reason , we performed a modern review of the literature analyzing the efficacy of gkrs in the treatment of patients who suffer...
[ "a 55-year - old caucasian female was undergoing elective coronary artery bypass surgery following a recent myocardial infarction . intravenous midazolam was given to the patient in the holding area , and the right radial artery was cannulated . in the operating room , intraoperative monitors , included five - lead...
a carbon dioxide ( co2 ) embolism during endoscopic vein harvesting is a rare but potentially fatal complication . early and accurate diagnosis is crucial for limiting the extent of the embolism and stabilizing the resulting cardiovascular compromise . we report a case of co2 embolization during endoscopic vein harvest...
[ "drywood termites cause significant damage to wood in structures in the united states , with two species , incisitermes minor ( hagen ) and cryptotermes brevis ( walker ) , being responsible for the majority of damage ( su and scheffrahn , 1990 ; grace , 2009 ) . the economic cost of control and repair of damage is...
hydrocarbon mixtures extracted from fecal pellets of drywood termites are species - specific and can be characterized to identify the termites responsible for damage , even when termites are no longer present or are unable to be recovered easily . in structures infested by drywood termites , it is common to find fecal ...
[ "there \n is a need for computer methods that can calculate the aqueous solvation \n free energies of solute molecules accurately and efficiently . explicit - solvent models provide a physically \n accurate and atomistically detailed model of solvent , but they can \n be computationally expensive . boltzmann \n ( p...
previous work describes a computational solvation model called semi - explicit assembly ( sea ) . the sea water model computes the free energies of solvation of nonpolar and polar solutes in water with good efficiency and accuracy . however , sea gives systematic errors in the solvation free energies of ions ...
[ "hydatidosisis term used to refer to infection with the parasite larva in humans and echinococcosis restricted to infection with the adult stage in carnivorous animals ( 1 ) . recently , the genetics , structure and function of the human cytosolic gst enzyme with emphasis on their roles in the cellular metabolism h...
abstractbackgroundthe aim of this study was to detect the glutathione s - transferase(gst ) enzyme activity of healthy / cystic liver as a diagnostic biomarker for hydatidosis . in order to compare with liver tissue , the level of the gsts enzyme activity of parasite was also determined.methodsparasites were collected ...
[ "the risk of stroke and myocardial infarction is considerably increased in subjects with diabetes . already at the time of diagnosis of type 2 diabetes , many patients have manifest cardiovascular disease ( cvd ) . this could be due to a long presymtomatic period with increased glucose level as evident by the incre...
backgroundimpaired fibrinolysis is found in impaired glucose tolerance and type 2 diabetes , associated with components of the metabolic syndrome . there are no data concerning fibrinolysis in subjects with normal glucose tolerance that convert to diabetes.methodswe studied the activities of tissue plasminogen activato...
[ "selective serotonin reuptake inhibitors ( ssris ) , serotonin and norepinephrine reuptake inhibitors , and noradrenergic and specific serotonergic antidepressants are categorized as first - line treatments in many countries , including japan.1,2 thus , health care providers have the opportunity to choose an antide...
backgroundapproved doses of antidepressants in japan are usually lower than those in the usa and european union , but to date meta - analyses comparing antidepressants have all used the higher doses approved in the usa and european union and often have used indirect comparisons . the purpose of this study was to conduc...
[ "we all have a very different understanding of how we define a need for help . this is most clearly felt when encountering individuals who , despite outside temperatures below zero , prefer sleeping rough in the street over the warm place in an overnight homeless shelter that a social worker or other care worker ...
this paper examines the new teaching concept providing medical care on the fringe of society : participant observation and change in perspectives in the context of the interdisciplinary field of querschnittsbereich 2/q 2 ( the transdisciplinary section under ao , the german regulations for licensed physicians ) that ...
[ "foodborne liver and intestinal flukes are important groups of parasites from the public health point of view [ 1 - 4 ] . lao peoples democratic republic ( lao pdr ) is located in the middle of the indochina peninsula , and the mekong river runs through the whole length of the country from north to south . until th...
in this study , we found that haplorchis taichui , a heterophyid intestinal fluke , is highly prevalent , with heavy worm loads , among riparian people in saravane and champasak province , lao pdr . fecal specimens were collected from 1,460 people ( 717 men and 743 women ) in 12 riparian ( mekong river ) districts and ...
[ "for patients and families , the issue of data quality is personal . when treatment decisions or research conclusions are based on incomplete or inaccurate information a misdiagnosis , an incomplete medication list , the wrong demographic data ", "thanks in part to the power of health information technology , in...
introduction : for patients and families , the issue of data quality is personal . when treatment decisions or research conclusions are based on incomplete or inaccurate information a misdiagnosis , an incomplete medication list , the wrong demographic data care safety , quality , and outcomes suffer and patients an...
[ "adverse drug reactions ( adrs ) , including interactions , in older people are a common cause of admission to hospital1 and are also a common cause of disease in hospitalized patients . frail elderly patients appear to be particularly at risk of adrs . in some cases , this is because insufficient account is taken ...
rhabdomyolysis is a clinical and laboratory syndrome that is caused by various etiologies , involving the skeletal muscle . clarithromycin , like other macrolides , is an inhibitor of cyp450 3a4 , the major enzyme responsible for the metabolism of several drugs , in particular some statins . rhabdomyolysis related to m...
[ "supravalvar mitral ring is a circumferential ridge or membrane arising from the left atrial wall overlying the mitral valve and frequently attached to the mitral valve.1 variable in thickness and extent , the ring ranges from a thin membrane to a thick discrete fibrous ridge.2 the membranous variety may be difficu...
supravalvar mitral ring is a rare congenital heart defect of surgical importance . the condition is characterized by an abnormal ridge of the connective tissue on the atrial side of the mitral valve . it often substantially obstructs the mitral valve inflow . we herein introduce a case of a supravalvar mitral ring in a...
[ "in the recent millennium , the constant trend of change in the demands of the community as well as transforming the trend of knowledge production has highlighted the necessity for researchers to adopt a more comprehensive approach . increasingly , many academic disciplines are utilizing qualitative research ( qr )...
considering the nature of qualitative studies , the interaction between researchers and participants can be ethically challenging for the former , as they are personally involved in different stages of the study . therefore , formulation of specific ethical guidelines in this respect seems to be essential . the present...
[ "since the discovery of penicillin in 1928 by a scottish scientist alexander fleming followed by the release of many other earlier drugs onto the market to treat infection , the development of drug resistance in various sectors including aquaculture has been reported [ 13 ] . the misuse and abuse of the antimicrobi...
the administration of antimicrobials in aquaculture provides a selective pressure creating a reservoir of multiple resistant bacteria in the cultured fish and shrimps as well as the aquaculture environment . the objective of this study was to determine the extent of antibiotic resistance in aquaculture products and aqu...
[ "with an incidence rate of 0.92% , maternal puerperal lower extremity nerve injuries are rare . lateral femoral cutaneous neuropathy ( meralgia paraesthetica ) is the most common , followed by femoral neuropathy . nerve injuries are more likely to occur in nulliparae , in cases of prolonged stages of labour and ass...
we describe the case of a 32-year - old woman who developed bilateral heel numbness after obstetric epidural analgesia . we diagnosed her with bilateral neuropathy of the medial calcaneal nerve , most likely due to longstanding pressure on both heels . risk factors for the development of this neuropathy were prolonged ...
[ "haemotropic mycoplasmas ( haemoplasmas ) are bacterial organisms without cell walls that attach to and grow on the surface of red blood cells . three feline haemoplasma species are described : mycoplasma haemofelis ( mhf ) , candidatus mycoplasma haemominutum ( cmhm ) , and candidatus mycoplasma turicensis ( c...
this study investigated the prevalence of feline haemoplasma infections in a number of stray cat colonies in milan , northern italy . blood samples from 260 stray cats were evaluated , with conventional pcr , for the presence of dna associated with mycoplasma haemofelis ( mhf ) and candidatus mycoplasma haemominutum ...
[ "in a case - control study , 140 patients including two equal groups of traumatic due to traffic injuries and non - traumatic patients were evaluated . using the persian version of the conners adult adhd rating scale ( caars ) self - report ( screening version ) the study was performed in two university hospitals i...
objectivenowadays , it is well known that the attention - deficit / hyperactivity disorder ( adhd ) is not confined to children and adolescents . recent data showed that a considerable portion of the general adult population may be affected by adhd . on the other hand , the impact of adhd on driving performance , a maj...
[ "crh is a 41-amino - acid peptide hormone synthesized in the paraventricular nucleus of the hypothalamus . its function in the central nervous system is to stimulate the hypothalamic - pituitary - adrenal ( hpa ) axis as part of the stress response . crh is also produced in peripheral tissues including the placenta...
corticotropin releasing hormone ( crh ) production by the human placenta increases exponentially as pregnancy advances , and the rate of increase predicts gestational length . crh gene expression is regulated by camp in trophoblasts through a cyclic amp - response element ( cre ) , which changes its transcription facto...
[ "the three compounds lincomycin ( a natural antibiotic produced by streptomyces lincolnensis and discovered in 1961 ) , clindamycin , and pirlimycin ( two semi - synthetic derivatives of lincomycin ) comprise a group of clinically important antibiotics known as lincosamides . the structure of lincomycin ( fig . 1a...
lincosamides are a class of antibiotics used both in clinical and veterinary practice for a wide range of pathogens . this group of drugs inhibits the activity of the bacterial ribosome by binding to the 23s rna of the large ribosomal subunit and blocking protein synthesis . currently , three x - ray structures of the ...
[ "the rising prevalence of alzheimer s disease and related dementias ( henceforth referred to as dementia ) is emerging as a leading global health system challenge . effective early diagnosis and management models are required to mitigate its impact on patients , caregivers , and health - care systems . enhancing pr...
backgroundprimary care - based memory clinics ( pcmcs ) have been established in several jurisdictions to improve the care for persons with alzheimer s disease and related dementias . we sought to identify key quality indicators ( qis ) , quality improvement mechanisms , and potential barriers and facilitators to the e...
[ "symptomatic supravesical obstructive uropathy in a patient with dual functioning kidneys is classically characterized by bilateral hydroureters / hydronephrosis and an empty urinary bladder . this obstruction may be secondary to metastatic abdomino - pelvic and retroperitoneal malignancies , ureteric calculi and r...
bilateral hydronephrosis is classic for supravesical obstructive uropathy causing uraemia with dual functioning kidneys . recently , a patient presented with uraemia and metastatic urinary bladder carcinoma but only unilateral right - sided hydronephrosis . a right ureteral stent was placed retrograde and no further in...
[ "in 1985 , smith pioneered phage display technology , an in vitro methodology and system for presenting , selecting and evolving proteins and peptides displayed on the surface of phage virion . since then , phage display has developed rapidly and become an increasingly popular tool for both basic research such as t...
as epitope mimics , mimotopes have been widely utilized in the study of epitope prediction and the development of new diagnostics , therapeutics , and vaccines . screening the random peptide libraries constructed with phage display or any other surface display technologies provides an efficient and convenient approach ...
[ "reversible focal lesions in the splenium of the corpus callosum ( scc ) have been found in patients with various conditions including seizures , antiepileptic drug toxicity or withdrawal , viral encephalitis , hypoglycemia , wernicke 's encephalopathy , marchiafava - bignami disease , sympathomimetic - induced kal...
this is the first case of virus - associated encephalitis / encephalopathy in which the pathogen was hantaan virus . a 53-yr - old man presented fever , renal failure and a hemorrhagic tendency and he was diagnosed with hemorrhagic fever with renal failure syndrome ( hfrs ) . in the course of his illness , mild neurolo...
[ "as is the most common cause of left ventricular outflow obstruction in children and adults . it is most common type of valvular heart disease in europe and north america , occurring in 27% of the population over 65 years of age . medical therapy alone is not effective for the long - term management of aortic valve...
aortic valve replacement ( avr ) remains the cornerstone of treatment for symptomatic critical aortic stenosis ( as ) . it is a class i indication that symptomatic patients with critical as undergo either surgical or transcatheter aortic valve replacement ( tavr ) . we present a patient with critical as and new angina ...
[ "the various blood cell lineages in mammals arise from a multipotent haematopoietic stem cell via particular differentiation pathways . one of these pathways , erythropoiesis , leads to the production of red blood cells ( rbcs ) , which transport oxygen and carbon dioxide around the body by means of the intracellul...
haemoglobinopathies such as thalassaemia and sickle cell disease present a major health burden . currently , the main forms of treatment for these diseases are packed red blood cell transfusions and the administration of drugs which act to nonspecifically reactivate the production of foetal haemoglobin . these treatmen...
[ "he had a left ventricular ejection fraction of 42% and regional wall motion abnormalities compatible with multi - vessel territories . coronary angiography findings revealed total occlusion at the proximal left anterior descending artery ( lad ) , 50 - 75% stenosis at the mid to distal left circumflex artery , and...
although compressed gas ( co2 ) blowers have been used safely to aid accurate grafting during off - pump coronary bypass surgery , hemodynamic collapse due to gas embolism into the right coronary artery may occur . supportive measures to facilitate gas clearance by increasing the coronary perfusion pressure have been r...
[ "multiple sclerosis ( ms ) is a chronic progressive inflammatory and neurodegenerative disease of human central nervous system ( cns ) which usually affects young adults , with a reported median age of onset of approximately 30 years.1 in approximately 85% of patients with ms , the disease is initially recognized b...
multiple sclerosis ( ms ) is a progressive immune - mediated neurodegenerative disease of human central nervous system ( cns ) , which causes irreversible disability in young adults . the cause and cure for ms remain unknown . pathophysiology of ms includes two arms : inflammatory demyelination and neurodegeneration . ...
[ "several imaging modalities including pa , occlusal and panoramic radiography , cone beam computed tomography ( cbct ) and ct are used before and after implant treatment as well as in the maintenance sessions . after successful implant placement , periapical radiography is usually a suitable imaging modality for lo...
objectives : this study aimed to compare the diagnostic accuracy of inverted and unprocessed digitized periapical radiographs for detection of peri - implant defects.materials and methods : a total of 30 osteotomy sites were prepared in three groups of control , study group 1 with 0.425 mm defects and study group 2 wit...
[ "upper gastrointestinal bleeding ( ugib ) is a major cause of mortality and morbidity accounting for about 56.5/100,000 hospitalization with a mortality rate of 8.2% . aorto - esophageal fistula ( aef ) , an abnormal anatomical communication between the aorta and esophagus is a rare cause of ugib . as the thoracic ...
aorto - esophageal fistula is a rare cause of upper gastrointestinal bleeding . thoracic aneurysm , the most common cause of this condition , will slowly increase over time and can erode the wall of the aorta creating a fistula and leading to torrential bleeding . high clinical suspicion is required for timely diagnosi...
[ "the discovery of the silicon pn junction is a landmark in the development of modern microelectronics . silicon and other inorganic semiconductors are the predominant materials in electronic manufacturing today ; however , the development of organic - based electronic components has been a focus of intensive resear...
in this study , we synthesized the new kinds of semiconducting polymeric gels having negative ( n - type ) and positive ( p - type ) counter ions as charge carriers . the polyacrylamide gel was doped with pyranine ( 8-hydroxypyrene-1,3,6-trisulfonic acid , trisodium salt ) , havingions as side groups and na+ as counter...
[ "in june 2014 , a 61-year - old female was admitted to keimyung university dongsan medical center because of a severe dry cough that had lasted for over 20 days . according to her medical history , she had undergone a hysterectomy in 2005 , and the pathologic diagnosis was leiomyoma of the uterus . in 2006 , chest ...
pulmonary benign metastasizing leiomyoma ( pbml ) is defined as metastasis of a leiomyoma to lung tissue . it was first reported in 1937 . p bml is known as a benign disease , but can undergo malignant transformation . only 1 case of the malignant transformation of pbml to leiomyosarcoma has been reported previously . ...
[ "copd is a common , usually progressive disease characterized by chronic inflammation of the airways and persistent airflow limitation . its prevalence is increasing worldwide , and it is expected to be the third largest global cause of mortality by the year 2030.1 in japan , a large epidemiological study ( the nip...
backgroundthe incidence of chronic obstructive pulmonary disease ( copd ) is increasing worldwide . in japan and other countries , epidemiological studies have found that many patients with copd are underdiagnosed and untreated , and thus , early detection and treatment of copd has been emphasized . screening questionn...
[ "the human cytomegalovirus ( cmv ) or human herpesvirus 5 is one of the major causes of congenital infections . its clinical manifestations range from asymptomatic forms ( 90% of cases ) to severe fetal damage and , in rare cases , death due to abortion . furthermore , 10%15% of the children who are asymptomatic at...
the fetal consequences of cmv infection make it one of the most serious infections contracted during pregnancy , but the scientific community is divided over the proposed implementation of preventive screening for anti - cmv antibodies . the aim of this study was to assess the incidence and risk of infection during pre...
[ "bladder cancer is the second most commonly diagnosed genitourinary malignancy in the usa , with an estimated 74,000 newly diagnosed cases and 16,000 deaths in 2015 . the incidence of bladder cancer rises with age , peaking between age 50 and 70 years , and is three times more common in men than in women . commonly...
introduction : non - muscle invasive bladder cancer ( nmibc ) comprises about 70% of all newly diagnosed bladder cancer , and includes tumors with stage ta , t1 and carcinoma in situ ( cis . ) since , nmibc patients with progression to muscle - invasive disease tend to have worse prognosis than with patients with prima...
[ "personalized medicine is defined by the use of genomic signatures of patients to assign effective therapies in order to achieve the best medical outcomes for individual patients , thus improving public health . despite the variety of clinical , morphological , and molecular parameters used to classify human malign...
numerous studies have demonstrated sex differences in drug reactions to the same drug treatment , steering away from the traditional view of one - size - fits - all medicine . a premise of this study is that the sex of a patient influences difference in disease characteristics and risk factors . in this study , we inte...
[ "in the last decade , preimplantation genetic diagnosis ( pgd ) has become an important alternative to prenatal diagnosis for couples at high risk of transmitting inherited disorders to their children . fluorescence in situ hybridization ( fish ) has been offered for gender selection in x - linked diseases ( 1 , 2 ...
ornithine transcarbamylase ( otc ) deficiency is an x - linked co - dominant disorder . a couple , with a previous history of a neonatal death and a therapeutical termination due to otc deficiency , was referred to our center for preimplantation genetic diagnosis ( pgd ) . the female partner has a nonsense mutation in ...
[ "musculoskeletal stiffness and limited range of motion ( rom ) can restrict functional joint \n movement , particularly during ankle supination following neurological diseases1 . ankle dorsiflexion rom restrictions impair \n dynamic balance and gait , which may contribute to secondary injuries ; reduced ankle rom a...
[ purpose ] the present study assessed the effects of using an unstable inclined board on the active and passive ankle range of motion in patients with ankle stiffness . [ subjects ] the study included 10 young female patients with ankle stiffness . [ methods ] the patients were divided into the following two gro...
[ "renal tubular involvement in sjgren 's syndrome ( ss ) usually manifests with fanconi syndrome , distal ( type 1 ) renal tubular acidosis ( rta ) , nephrogenic diabetes insipidus , and hypokalemia . , we describe a case a young female with ss who presented with features of gitelman syndrome and hypokalemic paralys...
we report a case of a young female patient who presented with weakness of upper and lower limbs . on evaluation , she had hypokalemia , hypomagnesemia , metabolic alkalosis and hypocalciuria . anti - ro ( ssa ) antibody was positive . she had an acquired gitelman syndrome due to primary sjgren 's syndrome ( ss ) . ss p...
[ "inadequate organization has been identified as an important cause of inappropriate courses of treatment for patients in the health care system [ 1 , 2 ] . a response to this challenge has been to focus on integrated health care and co - ordination between the actors involved in the process [ 37 ] . an illustrative...
objectivesthe aim of follow - up visits by the general practitioner and district nurse ( within a week after discharge from hospital ) is to reduce hospital readmissions and improve the overall wellbeing of the patient . there is strong evidence that these programmes are effective , but are difficult to implement becau...
[ "alzheimer s disease ( ad ) is a progressive neurodegenerative disorder starting with mild memory loss and manifesting in severe cognitive decline . neuropathologically , the disease is characterized by an extensive deposition of amyloid ( a ) peptides in extracellular amyloid plaques and by intracellular neurofib...
alzheimer s disease ( ad ) is one key medical challenge of the aging society and despite a great amount of effort and a huge collection of acquired data on molecular mechanisms that are associated with the onset and progression of this devastating disorder , no causal therapy is in sight . the two main hypotheses of ad...
[ "the union rate and hardware - related complications remain a major concern in these patients , especially following multilevel spinal fusion surgeries . developing an adjunct therapy that essentially supplements the mainstay surgical management is of great importance to these patients . multitudinous research to g...
abstractelderly patients with chronic nonresolving symptoms due to degenerative spine pathologies are prone to have poor surgical outcomes and hardware - related complications , especially following multilevel instrumented lumbar fusion surgeries . with intention of analyzing if teriparatide can be an effective adjunct...
[ "according to the world health organization 's recent update , diabetes , hypertension , and obesity are one of the top five continuing risk factors for cardiovascular deaths in the world . obesity is increasing substantially and is one of the major contributors of disease prevalence due to its pathophysiological l...
background . this study was carried out to establish the prevalence of cardiovascular risks such as hypertension , obesity , and diabetes in eastern nepal . this study also establishes the prevalence of metabolic syndrome ( ms ) and its relationships to these cardiovascular risk factors and lifestyle . methods . 14,4...
[ "balance is very important in daily activities of the elderly and greatly affects their \n quality of life . due to age - related changes , balance ability deteriorates . osteoarthritis is \n a degenerative disease that causes severe pain in elderly patients with low pain thresholds . \n research has shown that it ...
[ purpose ] the aim of this study was to examine the effects of horse - riding simulator exercise on balance in elderly with knee osteoarthritis . [ subjects and methods ] fifty elderly patients with knee osteoarthritis were recruited , a horse - riding simulator group performed exercise three times a week for ei...
[ ", medulloblastomas can be classified in 4 different molecular subtypes : wnt , shh , group 3 and group 4 . each of these molecular subtypes has specific underlying molecular features , gene expression , demographic characteristics and prognosis . sonic hedgehog ( shh ) medulloblastomas are characterized by activat...
abstractthe mechanisms leading to brain tumor formation are poorly understood . using ptch1+/ mice as a medulloblastoma model , sequential mutations were found to shape tumor evolution . initially , medulloblastoma preneoplastic lesions display loss of heterozygosity of the ptch1 wild - type allele , an event associate...
[ "a 33-year - old woman , ( gravida 3 , para 2 ) , at 34 weeks of gestation , presented with episodes of lightheadedness , and dyspnea . she was asymptomatic until 18 weeks of gestation , when she started having episodes of palpitations associated with presyncope . initially , the episodes were infrequent ( less tha...
ventricular tachycardia although not common , can occasionally complicate pregnancy . its presence may indicate an underlying cardiac structural abnormality , or undiagnosed congenital arrhythmic disease . however , some pregnant patients with ventricular tachycardia have structurally normal hearts . two cases of ventr...
[ "common sources include backyard burning , incineration of plastics , and chlorine bleaching of pulp in paper mills . documented health effects include acute and chronic effects , including chloracne , various types of cancers , reproductive diseases , circulatory and respiratory diseases , and diabetes . the tradi...
sphingomonas wittichii rw1 is a bacterium of interest due to its ability to degrade polychlorinated dioxins , which represent priority pollutants in the usa and worldwide . although its genome has been fully sequenced , many questions exist regarding changes in protein expression of s. wittichii rw1 in response to di...
[ "among dermatological disorders , erythematous dermatitis , or eczema , and psoriasis are the most common.1 dermatitis is defined as a superficial skin inflammation , characterized by poorly delimited erythema , and usually itchy crusts and scales.2 conventional measures to prevent eczema include avoidance of irrit...
backgroundboswellic acids ( bas ) show anti - inflammatory properties in a variety of inflammatory diseases , including rheumatoid arthritis , osteoarthritis , and asthma . a topical administration route is currently used to deliver active compounds in psoriatic and eczematous patients . in this double - blind study we...
[ "cell lines , cultures and transfections : a madin - darby bovine kidney cell \n line ( mdbk ) ( hsrrb , osaka , japan ) was cultured in dulbecco s modified eagle s medium ( dmem ) \n with 10% fetal calf serum ( fcs ) . a human cervical carcinoma cell line ( hela ) ( riken cell \n bank , tsukuba , japan ) was cultu...
clinically , many chemotherapeutics and ionizing radiation ( ir ) have been applied for the treatment of various types of human and animal malignancies . these treatments kill tumor cells by causing dna double - strand breaks ( dsbs ) . core factors of classical nonhomologous dna - end joining ( c - nhej ) play a...
[ "folic acid modification of magnetic nanoparticles could be used to facilitate uptake to specific cancer cells for cancer therapy and diagnosis . our results showed that the uptake of folic - acid modified nanoparticles by 5rp7 cancer cells was also much higher than that of 3t3 cells . this modification can be used...
background : magnetic nanoparticles show great promise for use as tools in a wide variety of biomedical applications . the purpose of this study was to investigate the potential effects of methacrylamido - folic acid ( ma - fol)-modified magnetic nanoparticles on 5rp7 ( h - ras - transformed rat embryonic fibroblasts )...
[ "this is a retrospective cross - sectional survey involving students at the higher institute of sport and physical education in the city of sfax . data on age , weight , height , and smoking habits are collected routinely when students join the institute , and then the sport in which the student is injured in the l...
introductionfor obvious reasons , athletes are at greater risk of sustaining a lumber ( lower ) spine injury due to physical activity . to our knowledge , no previous studies have examined the prevalence of low back pain ( lbp ) in a tunisian sports and physical education institute.aimto assess the prevalence of lbp in...
[ "in modern society , health is a n important component , which requires sustained development ( 1 ) . in recent decades , a person s health has become one of the most important human rights among social groups throughout the world ( 2 ) . the meaning of health has been extended beyond borders , and different defini...
introductionhealth is an exclusive and subjective phenomenon , and one of the most important situations with regard to perception of health , arises when patients suffer from a chronic disease.this study was conducted within the qualitative research framework and aimed to explore the meanings of health as perceived by ...
[ "however , proper amount of daily water intake in a healthy individual is controversial . there is a prevalent thought that we all have to drink eight glasses of water daily , we try to clarify this topic from the perspective of avicenna and traditional persian medicine ( tpm ) .", "the most important traditional...
background : fluid intake is an essential factor in having a normal homeostasis . however , proper amount of daily water intake in a healthy individual is controversial . there is a prevalent thought that we all have to drink eight glasses of water daily , however , it lacks enough supportive evidence at least for heal...
[ "a 34year - old male presented for general examination on day 49 of a 50-day self - imposed fast , seeking approval to continue his fasting behavior . during this period , the patient reported only consuming water , tea , coffee ( with no milk or sugar ) , and a daily multivitamin tablet ( centrum performance ; pfi...
a 34-year - old obese male ( 96.8 kg ; bmi , 30.2 kg m1 ) volitionally undertook a 50-day fast with the stated goal of losing body mass . during this time , only tea , coffee , water , and a daily multivitamin were consumed . severe and linear loss of body mass is recorded during these 50 days ( final 75.4 kg ; bmi , 2...
[ "tangential tractions on the vitreomacular interface are usually responsible for the development of idiopathic macular holes . the prevalence is 3.3/1000 and it shows a strong female predominance.1 in the past , it was known as a rare , untreatable disorder leading to central loss of vision . in 1991 , kelly and we...
purpose : the evaluation of anatomic and visual outcomes in macular hole cases treated with internal limiting membrane ( ilm ) peeling , brilliant blue ( bb ) , and 23-gauge pars plana vitrectomy ( ppv).materials and methods : fifty eyes of 48 patients who presented between july 2007 and december 2009 with the diagnosi...
[ "the study included 340 whites from italy with type 2 diabetes ( according to american diabetes association 2003 criteria ) and coronary artery disease ( cad ) , as indicated by previous myocardial infarction ( mi ) or > 50% stenosis of at least one major vessel at coronary angiography , or both . these individuals...
objectiveinsulin resistance ( ir ) and cardiovascular disease may share a common genetic background . we investigated the role of ir - associated enpp1 k121q polymorphism ( rs1044498 ) on cardiovascular disease in high - risk individuals.research design and methodsa prospective study ( average follow - up , 37 months )...
[ "in the past two decades , molecular biology research has revealed the intimate mechanisms of epidemiologically significant diseases , such as cancer , infections and immunological disorders . as the next step beyond seeking the mechanisms involved , scientists are now increasingly making it possible to regulate hu...
synthetic rna - based regulatory systems are used to program higher - level biological functions that could be exploited , among many applications , for in vivo diagnostic and therapeutic applications . chen and colleagues have recently reported a significant technological advance by producing an rna modular device bas...
[ "the wilms ' tumor suppressor gene ( wt1 ) , located at chromosome 11p13 , has 10 exons , spans -50 kb , and encodes a zinc - finger - transcription factor presumed to regulate the expression of numerous target genes through dna binding ( 1 ) . wt1 was initially identified as a gene inactivated in wilms ' tumor , a...
here we report two cases of isolated diffuse mesangial sclerosis ( idms ) with early onset end - stage renal failure . these female patients did not show abnormalities of the gonads or external genitalia . direct sequencing of wt1 pcr products from genomic dna identified wt1 mutations in exons 8 ( 366 arg > his ) and 9...
[ "titanium dioxide ( tio2 ) is a component of many sunscreens , soaps , shampoos , toothpastes , cosmetics , paper products , plastics , ink , paint , and building materials 1 in both its bulk form and its nanoform . it is also used in human food as a colorant and inactive ingredient , where it can also be present i...
abstracttitanium dioxide nanoparticles are photoactive and produce reactive oxygen species under natural sunlight . reactive oxygen species can be detrimental to many organisms , causing oxidative damage , cell injury , and death . most studies investigating tio2 nanoparticle toxicity did not consider photoactivation a...
[ "we report 2 patients infected with panton - valentine leukocidin ( pvl)positive mrsa t034 . each patient had a medical history typical of that reported for community - acquired mrsa of other lineages , which in most cases are pvl positive ( 8) . the first patient , a previously healthy 36-year - old male physiothe...
panton - valentine leukocidin ( pvl)positive methicillin - resistant staphylococcus aureus ( mrsa ) , sequence type 398 is believed to be of animal origin . we report 2 cases of infection due to pvl positive mrsa , spa type t034 , in patients in sweden who had had no animal contact .
[ "the selective melatonin receptor agonism effect of ramelteon is useful for insomnia.1 ) here we wanted to present a refractory chronic migraine case , who had significant improvements in migraine after using ramelteon .", "the precipitating factors were the stress , increase in physical activities and sudden col...
the selective melatonin receptor agonism effect of ramelteon is useful for insomnia . here we wanted to present a refractory chronic migraine case , who had significant improvements in migraine after using ramelteon . the possible mechanism for the ramelteon in the migraine relief might be related to melatonin effects ...
[ "it was previously suggested that atherothrombotic infarction ( ati ) and lacunar infarction ( li ) , as two different subtypes of ischemic stroke , might also differ in the set of the relevant risk factors , with ati being more associated to the atherogenic risk factors in contrast to li . . however , decreased ...
we analyzed ( a ) insulin sensitivity ( is ) and ( b ) glutathione peroxidase ( gsh - px ) , glutathione reductase ( gr ) , and superoxide dismutase ( sod ) antioxidant enzyme activity in type 2 diabetic ( t2d ) patients with atherothrombotic infarction ( ati ) ( group a ) , lacunar infarction ( li ) ( b ) , or without...
[ "the formation of spores is a survival mechanism of microorganisms when exposed to unfavorable environmental conditions ( e.g. , heavy metal stress , nutrient limitations ) leading to a dormant or resting growth state [ 1 , 2 ] . a variety of bacteria identified in diverse habitats including soil is able to for...
spore formation is a survival mechanism of microorganisms when facing unfavorable environmental conditions resulting in dormant states . we investigated the occurrence of bacterial endospores in soils from various locations including grasslands ( pasture , meadow ) , allotment gardens , and forests , as well as fluvi...
[ "alzheimer 's disease ( ad ) is a common neurodegenerative disease in the central nervous system . the pathological features of ad include senile plaques formed by extracellular amyloid ( a ) aggregation , neurofibrillary tangles formed by abnormal accumulation of hyperphosphorylated tau protein , synaptic impairm...
background : amyloid ( a ) deposits and the endoplasmic reticulum stress ( ers ) are both well established in the development and progression of alzheimer 's disease ( ad ) . however , the mechanism and role of a-induced ers in ad - associated pathological progression remain to be elucidated.methods:the five familial ...
[ "according to the world health organization , diabetes mellitus ( dm ) is one of the most common chronic diseases in the world , affecting 9.3 % of all adults older than 25 years . diabetes poses a high risk for the development of cardiovascular diseases ( cvd ) , because it heralds an accelerated process of athe...
backgroundthe influence of diabetes mellitus on myocardial ischemic preconditioning is not clearly defined . experimental studies are conflicting and human studies are scarce and inconclusive.objectivesidentify whether diabetes mellitus intervenes on ischemic preconditioning in symptomatic coronary artery disease patie...
[ "most malignant heart tumors are sarcomas : myxosarcoma , liposarcoma , angiosarcoma , fibrosarcoma , leiomyosarcoma , osteosarcoma , synovial sarcoma , rhabdomyosarcoma , undifferentiated sarcoma , reticulum cell sarcoma , neurofibrosarcoma , and malignant fibrous histiocytoma . arrhythmias can develop from intraa...
backgroundtotal artificial heart ( tah ) implantation in patients with aggressive tumor infiltration of the heart can be challenging.case reportwe report on a patient with a rare primary undifferentiated high - grade spindle cell sarcoma of the mitral valve and in the left atrium , first diagnosed in 2014 . the referri...
[ "cannabis is a prominent political , health , and law enforcement issue in north america that is currently receiving a great deal of attention . as we watch the effects of the legalization of cannabis in colorado , washington , alaska , oregon , and the district of columbia , other jurisdictions are debating the fu...
cannabis is the most commonly used illicit substance among youth . recent policy developments and ongoing debate related to this drug underscore the urgent need to clear the smoke and better understand what the scientific evidence says about the health and behavioral effects of cannabis use , particularly on youth wh...
[ "hypertension ( htn ) is the most common comorbidity in the world with significant public health implications [ 1 , 2 ] . the overall u.s . prevalence of hypertension among adults ages 18 years in 20052008 was 30.9% and was highest among persons ages 65 years ( 69.7% ) and non - hispanic blacks ( 44% ) . ...
hypertension ( htn ) is the most common co - morbidity in the world , and its sequelae , heart failure ( hf ) is one of most common causes of mortality and morbidity in the world . current understanding of pathophysiology and management of htn in hf is mainly based on studies , which have mainly included whites . among...
[ "radiological investigations and therapeutics have become an integral part of the management of critically ill patients in the intensive care unit ( icu ) . patients admitted to the icu routinely undergo bedside imaging procedures such as chest radiographs for diagnosing heart , lung and other pathology , and for c...
background and aims : with the expanding use of diagnostic and therapeutic radiological modalities in critically ill patients , doctors working in intensive care units ( icus ) are increasingly exposed to ionizing radiation . this risk of radiation exposure occurs not only during bedside radiologic procedures , but als...
[ "despite the huge burden of hepatitis b worldwide , with an estimated 350 million people chronically infected , very few patients in low- and middle - income countries are currently receiving antiviral treatment . this is largely to blame on lack of access to viral load quantification , because this is considered a...
viral hepatitis claims one million lives each year . scaling up treatment for hepatitis b and c in resource - limited settings is not possible without access to reliable diagnostic tools . this article gives an overview of current technologies and the pipeline for easy - to - use assays for serological and virological ...