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[ "high resolution transmission electron microscopy and high angle annular dark - field scanning transmission electron microscopy were employed to investigate the microstructure and the epitaxial growth of the structures . room temperature ferroelectric and ferrimagnetic domains of the heterostructures were imaged by...
epitaxial heterostructures combining ferroelectric ( fe ) and ferromagnetic ( fim ) oxides are a possible route to explore coupling mechanisms between the two independent order parameters , polarization and magnetization of the component phases . we report on the fabrication and properties of arrays of hybrid epitaxial...
[ "malnutrition is a common and serious problem among geriatric patients , particularly for those who are diagnosed with lung cancer caused by declined functional reserve of visceral organs , decreased stability of the internal environment , and effects of acute or chronic diseases . malnutrition can lead to increase...
purposethis study assessed the nutritional status of elderly chinese lung cancer inpatients using a revised version of the mini - nutritional assessment ( mna ) tool.patients and methods : the revised version of the mna tool was used to assess the nutritional status of 180 elderly chinese lung cancer inpatients prior t...
[ "population aging can be considered as the most evident and dynamic aspect of modern demography , influencing the economy and public health in a significant way . the world has experienced a modest increase in the population above 60 years of age over the last six decades from 8% to 10% . however , there were 204 ...
introduction dizziness is a symptom that can lead to falls , which , in turn , undermine ons independence and autonomy , leading to several comorbidities . the practice of physical exercise , however , can help prevent falls . objective the objective of this study is to confirm the association between physical ex...
[ "we measured the differences in stiffness between extrafloral nectaries of v. faba and the tissue that surrounds them . we mounted 20 stipules from 20 , 18-day - old plants on adhesive tape that was attached ( sticky side up ) to the surface of a piece of flat styrofoam . we did a penetrometer test to measure the i...
abstractextrafloral nectaries play an important role in plant defense against herbivores by providing nectar rewards that attract ants and other carnivorous insects . however , extrafloral nectaries can themselves be targets of herbivory , in addition to being exploited by nectar - robbing insects that do not provide d...
[ "health systems based on primary health care ( phc ) distribute health care more equitably , are more cost effective and have better overall health outcomes and impact than health systems based on specialist care ( 1 ) . this is the foundation of the health for all concept of alma - ata , adopted by the world heal...
background.health-care systems based on primary health care ( phc ) are more equitable and cost effective . family medicine trains medical doctors in comprehensive phc with knowledge and skills that are needed to increase quality of care . family medicine is a relatively new specialty in sub - saharan africa.objective....
[ "of those deaths , an estimated 7.3 million were due to coronary heart disease and 6.2 million due to stroke . a disproportionate amount of those deaths , over 80% , take place in low- and middle - income countries and occur at similar rates among men and women . not surprisingly , elevated blood pressure levels ar...
excess intake of dietary salt is estimated to be one of the leading risks to health worldwide . major national and international health organizations , along with many governments around the world , have called for reductions in the consumption of dietary salt . this paper discusses behavioural and population intervent...
[ "the associated edema which may develop within an hour is the leading cause of potential life - threatening airway compromise . the disease may show variation in terms of its presentation and clinical course , which needs to be addressed carefully before making any airway management plan . literature is convincing ...
airway management of adult patients with acute supraglottitis is challenging . the sign and symptoms of the disease may show marked variation in terms of severity and progression . thorough evaluation is required before selecting any particular approach . we report the case of an adult patient with acute supraglottitis...
[ "a 15-year - old boy had complained of motility limitation in the right eye since a young age . his visual acuity was 20/20 in each eye , although an ocular motility examination revealed markedly limited abduction and mildly limited adduction in his right eye ( fig . 1 ) . on attempted adduction of the right eye , ...
we report a case of pseudo - duane 's retraction syndrome with entrapment of the medial rectus muscle in an old medial orbital wall fracture presenting identical clinical symptoms as duane 's retraction syndrome . a 15-year - old boy presented with persistent limited right eye movement since a young age . examination s...
[ "lumbar spine instability has been reported to be the leading cause of chronic back \n pain1 . an a abnormal vertebral joint \n creates mechanical lesions and pains in the lumbar spine , decreasing stability and \n increasing the range of motion , resulting in functional degeneration2 . these negative patterns have...
[ purpose ] the purpose of this study was to provide the data for constructing an integrated exercise program to help restore muscle strength and stability through extension strength exercise in adult females with lumbar disc herniation . [ subjects and methods ] an 8-week exercise program for lumbar muscle exten...
[ "this article presents statistics on health care utilization , prices , expenses , employment , and work hours , as well as on national economic activity . some of these statistics are based on sample surveys conducted monthly or quarterly by government agencies or private organizations , and are available 1 to 3 m...
this regular feature of the journal includes a discussion of each of the following four topics : community hospital statistics ; employment , hours , and earnings in the private health sector ; health care prices ; and national economic indicators . these statistics are valuable in their own right for understanding the...
[ "urinary retention and voiding dysfunction ( vd ) symptoms ( hesitancy , straining to void , difficulty in starting micturition , diminished stream , and sensations of incomplete emptying of the bladder ) are common and problematic features occurring after surgery for stress urinary incontinence ( sui ) , especiall...
objectives : to determine whether the completion of a voiding dysfunction ( vd ) questionnaire could have a good predictive value for uroflowmetry findings , in a population of stress urinary incontinence ( sui ) women.materials and methods : from a urodynamic database of 415 sui women , 93 with isolated sui who underw...
[ "scurvy is a disease that played an important role in history and used to be the number one killer of sailors . it is still diagnosed in third - world countries because of malnutrition and in epidemic form in refugee camps .", "a 35-year - old patient was seen at the emergency department of a level 1 trauma centr...
scurvy is a disease that played an important role in ancient history and used to be a notorious cause of death in sailors . nowadays , scurvy is not a common diagnosis in the civilized world , but this case report indicates that this old - fashioned disease is not extinct at all and still exists but in a different pati...
[ "human movement can be classified into walking and running , the latter of which easily \n fatigues the lower limb muscles1,2,3,4 . during running , the lower limbs must cope with the repeated \n transient impact of vertical ground reaction force ( grf ) , which is an abrupt collision force \n equal to about 1.5- t...
[ purpose ] the present study aimed to determine changes in muscle activity while moving on a treadmill at various speeds . [ subjects ] the activities of the left vastus lateralis , vastus medialis , hip adductors , lateral head of gastrocnemius , medial head gastrocnemius , soleus , and tibialis anterior of 10 ...
[ "", "the online version of this article ( doi:10.1007/s13300 - 015 - 0133-z ) contains supplementary material , which is available to authorized users .", "chronic kidney disease ( ckd ) is a common condition in patients with type 2 diabetes ( t2 dm ) . an estimated 2035% of patients with t2 dm have moderate to...
introductionchronic kidney disease ( ckd ) is common in patients with type 2 diabetes ( t2 dm ) and makes them particularly susceptible to safety / tolerability issues related to many classes of oral antihyperglycemic agents ( oaha ) . dipeptidyl peptidase-4 inhibitors ( dpp-4is ) like sitagliptin are generally well to...
[ "the use of the kuntscher nail has been the most important advancement in trauma surgery .", "he had an acetabulum fracture and a femoral shaft fracture treated 30 years ago with a reamed kuntscher femoral nail . lateral hip approach was performed and after attempting to remove the nail with the specific tools be...
introduction : the use of the kuntscher nail has been the most important advancement in trauma surgery . one of the problems is the difficulty to remove it . a new extraction technique is described in the present case report.case report : a 46-year - old man was referred for hip osteoarthritis . he had an acetabulum fr...
[ "the anticancer agent 5-fluoro-2-deoxyuridine ( floxuridine ) has been shown to be clinically effective in the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver . however , the adverse effects associated with chemotherapeutics are still unresolved , and many efforts have been mad...
dipeptide monoester prodrugs of floxuridine were synthesized , and their chemical stability in buffers , resistance to glycosidic bond metabolism , affinity for pept1 , enzymatic activation and permeability in cancer cells were determined and compared to those of mono amino acid monoester floxuridine prodrugs . prodrug...
[ "the mammalian order primate that includes humans , apes , and monkeys in addition to several other organisms can be traced to the late cretaceous period . the rhesus macaque is in many ways an ideal model organism , being closely related to humans ( sharing a common ancestor about 25 million years ago ) and also s...
mobile genetic elements ( mges ) are fragments of dna that can move around within the genome through retrotransposition . these are responsible for various important events such as gene inactivation , transduction , regulation of gene expression and genome expansion . the present work involves the identification and st...
[ "the prevalence of ulcerative colitis ( uc ) has increased each year for the past several decades . a large - scale population - based cohort study shows that the flare - up rate in women is 1.2 times higher than that in men . accordingly , female gender appears to be a risk factor for frequent uc flare - up . fema...
a 36-year - old woman who had been diagnosed with ulcerative colitis at the age of 17 years was referred to our hospital because of severe abdominal pain and repeated bloody diarrhea that persisted during pregnancy despite combination therapy with high - dose corticosteroids and weekly granulocyte and monocyte adsorpti...
[ "only a few cases of pulmonary vascular tumors diagnosed using endobronchial ultrasound - guided transbronchial needle aspiration ( ebus - tbna ) have been reported in the literature . they frequently present as filling defects in the pulmonary vasculature on computed tomography ( ct ) making it challenging to dist...
leiomyosarcoma of the pulmonary vasculature is an extremely rare condition that has not been previously diagnosed by endobronchial ultrasound ( ebus ) bronchoscopy . we present the case of a 43-year - old white male with a history of leiomyosarcoma who was diagnosed with pulmonary embolism 2 years ago . as the filling ...
[ "transitional cell carcinoma ( tcc ) of the urinary bladder can present as a non - muscle invasive or as a muscle - invasive lesion . the majority of patients ( approximately 75% ) present with non - muscle invasive tumors , which are limited to the mucosa ( ta ) or the lamina propria ( t1 ) ( 1 ) . . however , cis...
we developed nomograms to predict disease recurrence in patients with ta , t1 transitional cell carcinoma of the bladder . thirty - eight training hospitals participated in this retrospective multicenter study . between 1998 and 2002 , a total of 1,587 patients with newly diagnosed non - muscle invasive bladder cancer ...
[ "endobronchial tuberculosis ( ebtb ) is a form of tuberculous infection that involves mainly the trachea and/or bronchi . the disease is often mistaken for more common lung diseases like pneumonia , asthma , lung cancer and other lung diseases . endobronchial stenosis is a common complication of ebtb despite the us...
endobroncheal tuberculosis is defined as tuberculous infection of the tracheobronchial tree with microbial and histopathological evidence . the disease is usually mistaken for other lung diseases including lung cancer . bronchial stenosis is a common complication of this type of tuberculosis despite the use of effectiv...
[ "the present study was conducted in the psychiatry outpatient department of a tertiary care hospital during one year after obtaining clearance from institutional ethical committee . their sociodemographic profile , characteristics of migraine , psychiatric history , detailed physical examination as well as mental s...
background : migraine is a common disorder which has psychiatric sequelae.objective:the objective of this study was to determine the clinical pattern and psychiatric comorbidity of migraine.materials and methods:100 cases of migraine seen over a period of one year were analysed to know the sociodemographic characterist...
[ "medullary thyroid carcinoma ( mtc ) is a rare neuroendocrine cancer that originates from thyroid parafollicular calcitonin-(ct- ) producing cells . mtc accounts for approximately 4% of all thyroid malignancies ; approximately 75% of these cases occur in the sporadic form , and 25% occur in the hereditary form [ 13...
parafollicular c - cell - derived medullary thyroid cancer ( mtc ) comprises 3% to 4% of all thyroid cancers . while cytotoxic treatments have been shown to have limited efficacy , targeted molecular therapies that inhibit rearranged during transfection ( ret ) and other tyrosine kinase receptors that are mainly involv...
[ "all of the effects of antimicrobial agents against microbes , including the delineation of microbial resistance , are based upon the results of in vitro susceptibility testing . most of these susceptibility tests only measure bacteriostatic activity even though the agent being tested may have bactericidal activity...
the global emergence of antibacterial resistance among common and atypical respiratory pathogens in the last decade necessitates the strategic application of antibacterial agents . the use of bactericidal rather than bacteriostatic agents as first - line therapy is recommended because the eradication of microorganisms ...
[ "sponges play an important role in the benthic - pelagic coupling on coral reefs ( lesser 2006 ) . the sponge community sequesters and processes organic matter and as such conserve energy and nutrients for the reef ecosystem . it is generally assumed that sponges on the fore - reef slope mainly trap allochthonous o...
the diet of cavity sponges on the narrow fringing reefs of curaao , caribbean was studied . the origin and resources of the bulk food of these sponges , i.e. , dissolved organic matter ( dom ) , were identified using stable carbon and nitrogen isotopes and fatty acid biomarkers . we found that phytoplankton and its der...
[ "the asialoglycoprotein receptor ( asgpr ) ( also known as the ashwell receptor ) mediates the capture and endocytosis of galactose- ( gal ) and n - acetylgalactosamine- ( galnac ) terminating glycoproteins . the relevance of this function has been the subject of much debate ; the primary role may be the removal of...
background . the asialoglycoprotein receptor ( asgpr ) is a hepatic receptor that mediates removal of potentially hazardous glycoconjugates from blood in health and disease . the receptor comprises two proteins , asialoglycoprotein receptor 1 and 2 ( asgr1 and asgr2 ) , encoded by the genes asgr1 and asgr2 . design a...
[ "the prevalence of obesity in the united states has increased over the past several decades . according to the national health and nutrition examination survey ( nhanes ) results , between the years of 1988 and 1994 , 22.9% of adults aged 20 years and older exceeded the criteria for adult obesity [ body mass index ...
the prevalence of childhood obesity in the united states increased more than three - fold from 1976 1980 to 2007 2008 . the presidential youth fitness program s fitnessgram is the current method recommended by the president s council on fitness , sports & nutrition for assessing health - related fitness factors , inc...
[ "brown tumor is a non - neoplastic giant cell lesion characterized by increased circulating levels of parathyroid hormone ( pth ) . it is usually an uncommon lesion occurring with the frequency of 4.5% in primary hyperparathyroidism ( hpt ) and 1.5 - 1.7% in cases of secondary hpt , with overall incidence of 0.1% ....
brown tumor is a giant cell lesion associated with hyperparathyroidism . it is a non - neoplastic condition and represents terminal stage of the remodeling process in hyperparathyroid state . we report a case of brown tumor with multiple lesions in craniofacial region associated with ectopic parathyroid adenoma reveale...
[ "during april october 2009 , bird bandings were conducted in the protected area of finca ribavellosa in la rioja , spain ( 4214n , 254w ) . ticks were collected from birds and classified through taxonomic keys ( 7 ) and molecular methods ( 8) . dna was individually extracted by using 2 incubations of 20 minutes ea...
we amplified gene sequences from anaplasma phagocytophilum , borrelia garinii , b. valaisiana , b. turdi , rickettsia monacensis , r. helvetica , r. sibirica sibirica , and rickettsia spp . ( including candidatus rickettsia vini ) in ticks removed from birds in spain . the findings support the role of passerine birds a...
[ "central nervous system drugs ( 58.7 % ) were the most prescribed class of inappropriate medications in korean long - term care facilities.inappropriate medication use was associated with the number of co - medications and long - term care insurance grade 3 , which means less dependence and a requirement of low - ...
backgroundelderly residents of long - term care facilities are more vulnerable to being prescribed inappropriate medications because of the high incidence of co - medication in this population resulting from the presence of multiple chronic diseases and also age - related changes in pharmacokinetics and pharmacodynamic...
[ "in patients with chronic hepatitis and in those with liver cirrhosis , detection of increasing incidences of hepatocellular carcinoma ( hcc ) requires careful monitoring every 36 months using ultrasound sonography ( us ) , computed tomography ( ct ) , magnetic resonance imaging ( mri ) , and frequent blood tests ...
key clinical messageautologous formalin - fixed tumor vaccine ( aftv ) suppressed re - recurrence for more than 32 months of multiple - recurrent hepatocellular carcinoma based on hepatitis c virus - induced liver cirrhosis in a case with previous recurrence interval , 51- , 28- , 12- , and 4-months . we detected glyp...
[ "in this and the next issue of critical care , john haddad presents a comprehensive review on the contributions of transcription factors to lung injury . the topic is large and ever changing , and the complete coverage of nuclear factor-b ( nf-b ) and hypoxia - inducible factor ( hif)-1 is spread over two issues ...
the role of oxidative stress in regulating transcription factors and specific gene responses in critical illness is a new and emerging area . a better understanding of the proinflammatory oxidant stimuli of reactive oxygen species generation and how this generates the clinical phenotype of acute lung injury by regulati...
[ "we enrolled 13 consecutive patients between march 2005 and march 2009 and who met the following inclusion criteria : 1 ) they were diagnosed with acral lentiginous melanoma by punch biopsy ; 2 ) their skin lesion confined to the foot ; 3 ) there was no skin or soft tissue disease on the ipsilateral lower leg . we ...
backgroundwe report on our experience with using a distally based island flap for soft tissue reconstruction of the foot in limb salvage surgery for malignant melanoma patients.methodsa distally based sural flap was used for 10 cases for the hindfoot reconstruction , and a lateral supramalleolar flap was used for 3 cas...
[ "techniques and equipment to accomplish endotracheal ( et ) intubation were the precursor to modern day invasive mechanical ventilation . in recent years , however , the popularity of the et tube has waned . clinically , the et tube is seen as an impediment to spontaneous breathing , a transit route for bacteria to...
concerns about the work of breathing imposed by the endotracheal tube have led clinicians to routinely use pressure support to overcome this resistive component . more recently , ventilator manufacturers have introduced systems to automatically overcome endotracheal tube resistance , regardless of tube diameter or pati...
[ "bed rest , heart failure , depletion of intravascular volume , and aging often induce hypotension when the body or trunk is upright.15 generally , a tachycardic response occurs due to vagal withdrawal according to the downward blood shift that occurs under orthostatic stress in healthy humans,6 although orthostati...
backgrounddownward shifts in blood volume with changing position generally cause tachycardic responses . age - related decreases in vagal nerve activity could contribute to orthostatic hypotension in older individuals . fowler s position is a reclined position with the back between 30 and 60 , used to facilitate breath...
[ "alzheimer 's disease ( ad ) is a progressive , neurodegenerative brain disorder which affects over 37 million people worldwide with an estimated global cost of over $ 600 billion in 2010 [ 1 , 2 ] . ad is a growing socioeconomic and financial burden due to its strong correlation with ageing ; around 1 in 3 peo...
lipid rafts are membrane microdomains , enriched in cholesterol and sphingolipids , into which specific subsets of proteins and lipids partition , creating cell - signalling platforms that are vital for neuronal functions . lipid rafts play at least three crucial roles in alzheimer 's disease ( ad ) , namely , in promo...
[ "in dentistry , the concept of aesthetics is extremely subjective and is related to beauty , harmony and the needs of the patient . the interactions between new restorative materials and techniques allow the reproduction of dental structures , restoring form and function in such a way that restorative procedures be...
enamel hypoplasia is a developmental defect of the enamel that is produced by a disturbance in the formation of the organic enamel matrix , clinically visible as enamel defects . disorders that occur during the stages of enamel development and maturation reduce the amount or thickness of the enamel , resulting in white...
[ "gastrointestinal lipomas are rare , mostly small and detected incidentally during endoscopic examination ( 1 ) . these tumours are benign proliferations of mature fatty tissue arising in the submucosa and predominately arise in the large intestine ( 51 - 70% ) preferentially on the right side . the majority of sym...
lipomas of the alimentary tract are rare tumours that can mimic malignant lesions . they are often small and asymptomatic although larger tumours can present with intusussception or as abdominal masses . we present a case of a transverse colon submucosal lipoma masquerading as a colonic adenocarcinoma leading to resect...
[ "pekinensis ) is a diploid ( 2n = 2x = 20 ) dicot with a genomic size of 550 mb ( http://www.brassica.info/resource/ ) . the species originated in china and now has become one of the most important and widely cultivated leaf vegetables in asia . the tight leafy head is the main edible part . after a long history o...
simple sequence repeats ( ssrs ) are among the most important markers for population analysis and have been widely used in plant genetic mapping and molecular breeding . expressed sequence tag - ssr ( est - ssr ) markers , located in the coding regions , are potentially more efficient for qtl mapping , gene targeting ,...
[ "much of the current success in clinical positron emission tomography ( pet ) can be attributed to the development of 2-(f ) fluoro-2-deoxy - d - glucose ( f18-fdg ) . it is the most commonly used radiopharmaceutical in the pet , with a half - life of 110 min . before the release of f18-fdg for human use , the qual...
background : the bacterial endotoxin test ( bet ) performed using gel clot method is a 60-min test and typically performed after the decay of the 2-(18f ) fluoro-2-deoxy - d - glucose ( f18-fdg ) sample to determine the endotoxin content . the objective of this study protocol was to perform bet testing of f18-fdg by ge...
[ "prostate cancer becomes one of the most common cancers in developed and developing countries [ 13 ] . it is because life expectancy rised ; age is one of the prostate cancer risk factors . moreover there is wide availability of prostate - specific antigen ( psa ) serum test , which makes possible to diagnose clini...
prostate cancer , due to wide availability of psa tests , is very often diagnosed in early stage , nowadays . this makes management of this disease even harder in every day oncology care . there is a wide range of treatment options including surgery , radiotherapy and active surveillance , but essential question is whi...
[ "only 2030% of patients with group a beta hemolytic streptococcus ( gabhs ) pharyngitis presents with classical symptoms of the disease . reliance on clinical judgment alone has a poor predictive value and results in 80% to 95% overestimation of disease [ 2 , 3 ] . diagnostic strategies for acute gabhs pharyngitis ...
background . uncertainty exists concerning the necessity of 10-day antibiotic treatment of group a beta hemolytic streptococcus ( gabhs ) pharyngitis . objective . to assess the incidence of gabhs recurrence and suppurative and nonsuppurative complications in relation to compliance . methods . ( design ) . prospectiv...
[ "myofascial pain syndrome ( mps ) can be caused by frequent muscle or fascial stiffness as a \n result of prolonged tension and muscle fatigue due to repetitive stress of muscles or \n overuse of particular muscles1 , 2 . mps activates trigger points in 54% of women and 45% of men , and is regarded as \n the most c...
[ purpose ] this study compared the differences in electrophysiological characteristics of normal muscles versus muscles with latent or active myofascial trigger points , and identified the neuromuscular physiological characteristics of muscles with active myofascial trigger points , thereby providing a quantitat...
[ " primary or secondary neurondocrine ( ne ) tumours of the female genital tract are rare . cervical small cell carcinoma and ovarian carcinoids are the most common gynaecological ne tumours .", "neuroendocrine tumours comprise a set of neoplasms that arises from the diffuse neuroendocrine cell system . these tum...
backgroundboth primary and secondary gynaecological neuroendocrine ( ne ) tumours are uncommon , and the literature is scarce concerning their imaging features.methodsthis article reviews the epidemiological , clinical and imaging features with pathological correlation of gynaecological ne tumours.resultsthe clinical f...
[ "adenoid cystic carcinoma ( adcc ) is a malignant salivary gland tumor that was first described by billroth in 1859 under the name cylindroma attributing to its cribriform appearance formed by the tumor cells with cylindrical pseudolumina or pseudospaces . the term adenoid cystic carcinoma was introduced by ewing...
adenoid cystic carcinoma is an uncommon , slow growing malignant salivary gland tumor that is characterized by wide local infiltration , perineural spread , propensity to local recurrence and distant metastasis . in this paper , the authors present a case of adenoid cystic carcinoma affecting the palate and involving t...
[ "the quantity of trauma victims and the management involved in attending them leads to a great workload in most hospitals and places an enormous amount of pressure on the health care system . furthermore , traumatic injuries have been reported as the leading cause of death in the first 40 years of life and appear t...
abstractobjectivesthe aim of this retrospective study was to compare the peculiarities of maxillofacial injuries caused by interpersonal violence with other etiologic factors.material and methodsmedical records of 3,724 patients with maxillofacial injuries in so paulo state ( brazil ) were retrospectively analyzed . th...
[ "the influence of protecting \n groups on the reactivity and selectivity \n of glycosyl donors is a widely recognized and exploited phenomenon . the corresponding influence of protecting groups on the anomeric \n equilibrium , while evident for many years , is less widely studied and exploited . recent examples of ...
a method for the investigation of the influence of protecting groups on the anomeric equilibrium in the sialic acid glycosides has been developed on the basis of the equilibration of o - sialyl hydroxylamines by reversible homolytic scission of the glycosidic bond following the dictates of the fischer ingold...
[ "familial hemiplegic migraine ( fhm ) is an autosomal dominant rare type of migraine with aura characterized by some degree of hemiparesis . fhm1 , fhm2 and fhm3 are caused by mutations in the ion - channel genes cacna1a , atp1a2 and scn1a , respectively [ 24 ] . the majority of fhm families have pure fhm , but cer...
we present a norwegian family with familial hemiplegic migraine ( fhm ) with possibly four affected in three generations . the family had a point mutation in the atp1a2 gene that caused a change of the amino acid valine to methionine ( v628 m ) . the symptoms were pure fhm with intra- and interindividual variability ,...
[ "a few days later , four more cases occurred among postal workers at the brentwood mail processing facility in the washington area . the appearance of new cases in different locations around the country suggested contamination with b. anthracis of several postal facilities . in each location , the population pote...
backgroundthe investigation of potential exposure to anthrax spores in a trenton , new jersey , mail - processing facility required rapid assessment of informatics needs and adaptation of existing informatics tools to new physical and information - processing environments . because the affected building and its compute...
[ "duodenal ulcer perforation is still a common complication of chronic peptic ulcer disease . despite the wide spread use of anti - secretory and h. pylori eradication therapy most of the literature pertaining to the situation in the developed world , showed that the disease is largely confined to the elderly patien...
introduction : perforated duodenal ulcer ( pdu ) is still seen frequently in the study center inspite of the free use of effective medical curative therapy . we then set out to ascertain the pattern of presentation , peculiar risk factors in the study environment , re - evaluate our method of management , and to see if...
[ "hemophilia b is a chronic hereditary disease characterized by a deficiency in factor ix ( fix ) activity . it is less common than hemophilia a which is due to factor viii ( fviii ) deficiency . according to the world federation of hemophilia global survey of 2014 , 178,500 persons were identified with hemophilia a...
regular prophylactic treatment in severe hemophilia should be considered an optimal treatment . there is no general agreement on the optimal prophylaxis regimen , and adherence to prophylaxis is a main challenge due to medical , psychosocial , and cost controversies . improved approaches in prophylaxis regimen of hemop...
[ "protease inhibitors have been purified from an array of leguminous and nonleguminous species encompassing torresea cearensis , erythrina caffra , dolichos lablab , crotalaria paulina , medicago scutellata [ 5 , 6 ] , canavalia gladiata , pisum sativum , dimorphandra mollis , swartzia pickellii , psophocarpus tetra...
a purification protocol that comprised ion exchange chromatography on deae - cellulose , affinity chromatography on affi - gel blue gel , ion exchange chromatography on sp - sepharose , and gel filtration by fplc on superdex 75 was complied to isolate two trypsin inhibitors from phaseolus vulgaris cv white cloud bean ...
[ "although about two - thirds of patients with epilepsy ( pwe ) treated with antiepileptic drugs ( aeds ) reach seizure - freedom , about one - third remains drug - resistant to the current therapies.1 despite the introduction of new aeds with a better pharmacokinetic and safety profile compared to old generation ae...
brivaracetam ( brv ) , a high - affinity synaptic vesicle protein 2a ligand , reported to be 1030-fold more potent than levetiracetam ( lev ) , is highly effective in a wide range of experimental models of focal and generalized seizures . brv and lev similarly bind to synaptic vesicle protein 2a , while differentiating...
[ "\n acute intussusception is one of the most common causes of acute abdomen in infants . management includes both surgical and non - surgical methods , with gradually increasing importance recently being accorded to the latter . conservative measures , including hydrostatic reduction , are the methods of choice for...
we present a case of infantile intussusception treated successfully using hydrostatic reduction , highlighting the importance of non - surgical techniques as the first line of management for this entity . physicians should strive for mastery over such techniques by extensive training to prevent unwanted surgical proced...
[ "aging , a multifactorial process of enormous complexity , is characterized by impairment of physiochemical and biological aspects of cellular functions ( harman 1992 ) . oxidative stress , an unavoidable consequence in the metabolism of oxygen in aerobic cells , is a major factor in the aging process and , in the ...
aging has been defined as the changes that occur in living organisms with the passage of time that lead to functional impairment and ultimately to death . free radical - induced oxidative damage has long been thought to be the most important consequence of the aging process . in the present study , an attempt has been ...
[ "cleft lip and palate ( clp ) patients are going through an extensive treatment with \n orthodontic and surgical correction of the position of teeth and hard and soft \n tissues . the aim of the primary surgery is to close the clefts of the lip and the \n soft palate . the aim of the secondary surgery is to close t...
abstractobjectivesto compare cleft lip and palate patients ' satisfaction with aesthetics and functional parameters after conventional advancement of the maxilla or by the use of distraction osteogenesis.material and methodscase series observational study . group of distraction osteogenesis ( do ) consisted of 15...
[ "a rising trend in the incidence and prevalence of inflammatory bowel disease ( ibd ) in asia has been recognized for the past two decades . the thiopurine drugs azathioprine ( aza ) and mercaptopurine are widely used for the treatment of ibd and have proven to be effective in both inducing and maintaining remissio...
the immunosuppressant azathioprine ( aza ) is widely used in the treatment of inflammatory bowel disease ( ibd ) for both inducing and maintaining remission . however , the adverse effects of aza can often necessitate a dose reduction or discontinuation . bone marrow suppression is one of the most serious complications...
[ "diabetic macular edema ( dme ) is a common complication of diabetic retinopathy ( dr ) and a leading cause of visual loss in this population [ 1 , 2 ] . major components of dme are retinal microvascular dysfunction and blood - retinal barrier ( brb ) breakdown with consequent increase in vascular permeability that...
purpose . we investigated two factors linked to diabetic macular edema ( dme ) , vitreous and serum levels of vascular endothelial growth factor ( vegf ) and uric acid ( ua ) in patients with dme , and compared the results with changes in optical coherence tomography ( oct ) and visual acuity ( va ) . methods . a pro...
[ "diabetes is the most frequent cause of end - stage renal disease in industrialised countries [ 1 , 2 ] . clinically , diabetic nephropathy is characterized by the development of albuminuria and a subsequent decline in glomerular filtration rate . this severe complication significantly influences the risk of cardio...
background . the innate immune system may have adverse effects in diabetes and cardiovascular disease . the complement system seems to play a key role through erroneous complement activation via hyperglycaemia - induced neoepitopes . recently mannan - binding lectin ( mbl ) was shown to worsen diabetic kidney changes...
[ "how to choose surgical approach in severe multilevel cervical cord compression case is a hot debate on spine surgery . some surgeons think anterior surgery should be of the primary choice , because of direct decompression , restoring intervertebral height and reconstruction of stability7,12 ) . some surgeons prefe...
objectiveto investigate the causes for failed anterior cervical surgery and the outcomes of secondary laminoplasty.methodsseventeen patients failed anterior multilevel cervical surgery and the following conservative treatments between feb 2003 and may 2011 underwent secondary laminoplasty . outcomes were evaluated by t...
[ "population aging is the process by which older individuals become a proportionally larger share of the total population . it was the most distinctive global demographic event that the world witnessed in the past century and is an important event for the twenty - first century too . it was initially experienced by ...
medications probably are the single most important health care technology in preventing illness , disability , and death in the geriatric population . age - related changes in drug disposition and pharmacodynamic responses have significant clinical implications ; increased use of a number of medications raises the risk...
[ "day care or ambulatory anaesthesia is as old as the history of anaesthesia itself . in the last few decades , it has gained significant popularity mainly because of the enormous cost savings and has therefore been accepted by the hospitals , patients and the insurance companies alike . however , the quality and ex...
background and aims : day care surgery offers respite from hospitalisation for specific surgical procedures and has many advantages . however , occasionally patients who undergo such surgery require hospitalisation for unanticipated complications . we aimed to determine their incidence and to identify factors associate...
[ "the relationship between the clotting cascade and the promotion or inhibition of the anti - inflammatory response continues to be defined through basic research . the potential key role of proteins that were originally believed to be exclusively involved in coagulation in the inflammatory response provides an exci...
the relationship between blood coagulation factors and the promotion or inhibition of the anti - inflammatory response continues to be defined through basic research . the potential key role of blood coagulation factors in the response during sepsis provides an exciting potential mechanism(s ) for modification through ...
[ "myelofibrosis ( mf ) belongs to the category of myeloproliferative neoplasms ( mpns ) and may present as a primary disorder ( primary myelofibrosis [ pmf ] ) or evolve from polycythaemia vera ( pv ) or essential thrombocythaemia ( et ) to post - pv or post - et mf.1 it is characterised by the clonal proliferation ...
myelofibrosis ( mf ) is a bcr - abl1negative myeloproliferative neoplasm that is mainly characterised by reactive bone marrow fibrosis , extramedullary haematopoiesis , anaemia , hepatosplenomegaly , constitutional symptoms , leukaemic progression , and shortened survival . as such , this malignancy is still orphan of ...
[ "a 45-year - old iranian woman was referred to the private clinic in the city of hamadan for implant consultation . her past medical history was not notable , and there was no evidence of systemic disease . she had no history of trauma to the mandible . in the extra - oral examination , intra - oral examination rev...
periapical cemento - osseous dysplasia ( pcod ) is a subtype of cemento - osseous dysplasia that usually occurs in middle - aged black women . this report described a case of a 45-year - old iranian woman who was diagnosed with pcod on the basis of cone beam computed tomographic ( cbct ) findings . cbct enabled detaile...
[ "endodontically treated teeth often loose substantial tooth structure from previous \n caries , pre - existing restorations , and/or endodontic treatment , which reduce tooth bulk and thickness of healthy dentin \n resulting in increased chances of fracture under function . controversy exists as to whether endodont...
objectivethis study investigated the effect of different ferrule heights on endodontically treated premolars.materials and methodsfifty sound mandibular first premolars were endodontically treated and then restored with 7-mm fiber post ( frc postec plus # 1 ivoclar - vivadent ) luted with self - polymerized resin...
[ "dichlorvos ( dimethyl-2 , 2-dichloro vinyl phosphate ) is an organophosphorous ( op ) insecticide with moderate human toxicity , used for insect control in food storage areas , greenhouses , barns and control of insects on livestock . parenteral dichlorvos administration with suicidal intention is rarely reported ...
current case report describes a 37-year - old female patient who was admitted to the hospital following subcutaneous injection of dichlorvos with an insulin syringe . the only peripheral cholinergic sign observed on admission was excessive salivation with bilateral pyramidal tract signs . locally she had necrosis of sk...
[ "transesophageal echocardiography ( tee ) is considered to be safe and relatively noninvasive diagnostic tool,1 ) however severe complications have been reported . the incidence of major tee - related complications range from 0.2% to 0.5% and mortality is reported to be < 0.01%.2345 ) among these complications , pr...
transesophageal echocardiography ( tee ) is considered relatively safe but semi - invasive . the hypopharyngeal and esophageal injury is infrequent complication of tee but could be serious , even life - threatening . we present a case of a 74-year - old man who experienced a deep neck infection secondary to hypopharyng...
[ "it has been reported that the prevalence and incidence of dementia in the united states have been either stable or even declining over the last 2 decades of the 1990s . this question is particularly relevant to the case of japan which is an economically advanced country like the us , but is believed to have a diff...
there is a paucity of data regarding trends in dementia and its subtype prevalence in japan . our aims in the current paper are to : ( 1 ) summarize epidemiological studies of dementia in japan including relevant details of study protocol and diagnostic criteria , ( 2 ) compare the age - specific prevalence of all - ca...
[ "chronic low back pain ( clbp ) refers to chronic pain around the lumbar vertebra sustained \n for over three months without serious pathological characteristics , regardless of the \n existence of sciatalgia1 . clbp causes pain \n and changes in the muscles , as well as decreases in contractile force and muscle ac...
[ purpose ] the purpose of this case study was to identify the effects of joint mobilization using kaltenborn - evjenth orthopedic manual therapy ( keomt ) and proprioceptive neuromuscular facilitation ( pnf ) techniques on a patient with chronic low back pain ( clbp ) and a lumbar transitional vertebra . [ metho...
[ " to learn about the normal anatomy of the neural tube on mri to recognise the mr appearance of neural tube defects to understand the value of mri in assessing ntds", "technological developments in diagnostic imaging have improved the diagnosis and treatment of congenital anomalies immensely , and this progress...
objectiveto assess the role of magnetic resonance imaging ( mri ) in the prenatal diagnosis of neural tube defects ( ntds).backgroundntds comprise a heterogeneous group of congenital anomalies that derive from the failure of the neural tube to close . advances in ultrasonography and mri have considerably improved the d...
[ "patient acuity has been increasing , patient turnover is higher , and patients are frequently of advanced age with several comorbid disorders . limited resources and the pressure for higher efficiency can result in the suboptimal delivery of healthcare . during treatment within the healthcare system , a significan...
abstractcurrently , no reported studies have evaluated intraoperative handover among anesthesia providers . studies on anesthetic handover in the us recovery room setting observed that handover processes are insufficient and , in many instances , significant intraoperative events are disregarded . an online survey tool...
[ "slc / ccl21 , normally expressed in high endothelial venules and in t cell zones of spleen and lymph nodes , strongly attracts t cells and dendritic cells ( dc ) [ 1 - 8 ] . slc / ccl21 recruits both nave lymphocytes and antigen stimulated dc into t cell zones of secondary lymphoid organs , co - localizing these e...
backgroundslc / ccl21 , normally expressed in high endothelial venules and in t cell zones of spleen and lymph nodes , strongly attracts t cells and dendritic cells ( dc ) . we have previously shown that slc / ccl21-mediated anti - tumor responses are accompanied by significant induction of ifn and the cxc chemokines ,...
[ "neonatal bacterial meningitis continues to be \n the most common serious infection of the central nervous system ( cns ) in \n newborns with high morbidity and mortality despite the availability of \n effective bactericidal antibiotics over the last sixty years [ 1 , 2 ] . this high morbidity and mortality are due...
iber is a regulator present in meningitic escherichia coli strain e44 that carries a loss - of - function mutation in the stationary - phase ( sp ) regulatory gene rpos . in order to determine whether iber is an sp regulator in e44 , two - dimensional gel electrophoresis and lc - ms were used to compare the proteomes...
[ "today , education has been assigned as an industry for human resource development for different walks of life . the students constitute the heart of the education system and they are the most affected ones by the strengths and weaknesses of the education system . the students form an identical subgroup compared to...
the objective of this study was to examine the coping patterns followed by the junior college students . further , an extensive effort was done to study the gender differences in coping patterns used by the students . this study was conducted in christ college , bangalore and on the first and second - year students of ...
[ "dermatomyositis ( dm ) is an uncommon idiopathic inflammatory myopathy that primarily affects skeletal muscle and skin with well - characterized cutaneous findings . it has been well documented that dm carries an increased risk of malignancy and can present as a paraneoplastic syndrome to multiple types of underly...
breast cancer is the most common cancer in women in the usa , with the lifetime incidence of 1 in 8 women . dermatomyositis ( dm ) is an uncommon idiopathic inflammatory myopathy that can manifest as a paraneoplastic syndrome of an underlying malignancy . here , we report a case of a patient who presented with breast c...
[ "taken together , malaria ( caused by plasmodium species ) , human african trypanosomiasis ( hat , caused by trypanosoma brucei ) , chagas disease ( caused by t. \n cruzi ) , and leishmaniasis ( caused by leishmania species ) represent diseases with an estimated combined burden of \n over 87 million disability - ad...
tropical protozoal infections are a significant cause of morbidity and mortality worldwide ; four in particular ( human african trypanosomiasis ( hat ) , chagas disease , cutaneous leishmaniasis , and malaria ) have an estimated combined burden of over 87 million disability - adjusted life years . new drugs a...
[ "\n acute appendicitis is considered as the most frequent cause of acute abdomen in young patients with a slight predominance in males . although its clinical diagnosis is simple , 20 - 30% of appendicitis cases are reported to be gangrenous or perforated because of delayed diagnosis , which can lead to increased m...
although complicated acute appendicitis is occasionally observed in general practice , the diagnosis of appendiceal abscess by colonoscopy is unusual . we report a case of appendiceal abscess with spontaneous drainage into the lumen of colon diagnosed during colonoscopy and resolved by the time of surgery .
[ "they possess binding sites specific to carbohydrates and have the capacity to interact with molecules of biological fluids and those present in cellular surfaces . lectins can substitute natural linkers and activate cellular responses through different roads of intracellular signalling or endocytosis of formed com...
the cramoll 1,4 is a well - studied lectin . however , few studies about its biodistribution have been done before . in this study , we radiolabeled the cramol 1,4 with tc-99 m and analyzed the biodistribution . the results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance m...
[ "the comingling of swine from numerous premises with varied management practices and their interaction with large numbers of exhibitors and visitors make agricultural fairs an ideal setting for the intra- and inter - species transmission of influenza a viruses ( iavs ) between swine and human populations . the freq...
influenza a virus infections occurring in exhibition swine populations at agricultural fairs during 2012 served as a source of h3n2 variant influenza a viruses transmitted to humans resulting in more than 300 documented cases . prior to the outbreak , this investigation was initiated to identify fair - level risk facto...
[ "", "turmeric ( curcuma longa l. ) of family zingiberaceae is industrially as well as pharmaceutically important crop extensively cultivated in india . it is a vegetatively propagated , polyploid crop commonly known as golden spice . because of its multipurpose use as food preservative , spice , therapeutic age...
turmeric is an economically valued crop , because of its utility in the food , pharmaceutical industries and ayurvedic medicine , attracts the attention in many areas of research work . in the present study , we executed resequencing through transcriptome assembly of the turmeric cultivar suvarna ( cl_suv_10 ) . resequ...
[ "the sense of coherence ( soc ) , which was proposed by antonovsky is based on the salutogenic model of health . the soc is composed of three factors ; ( 1 ) the stimuli derived from internal and external environments in the course of living are structured , predictable , and explicable ( comprehensibility ) ; ( 2 ...
background : people with a strong sense of coherence ( soc ) have a high ability to cope with stress and maintain good physical and mental health.aims:the aim of this study was to investigate the relationship between depressive state , job stress , and soc among nurses in a japanese general hospital.materials and metho...
[ "huntington 's disease ( hd ) is an autosomal dominant , progressive neurodegenerative disorder characterized by chorea , subcortical dementia and psychiatric symptoms . the causal hd gene has been identified as it15 , which has cag repeats in the open reading frame ( orf , in exon 1 ) just following the 5end of th...
huntington 's disease is characterized by choreic movements , psychiatric disorders , striatal atrophy with selective small neuronal loss , and autosomal dominant inheritance . the genetic abnormality is cag expansion in huntingtin gene . newer therapeutic strategies are evolving to treat this progressive disorder . th...
[ " walking ability is impaired in patients with peripheral arterial disease ( pad ) due to decreased blood flow to the skeletal muscle tissue used during walking . it has been demonstrated that walking distance is associated with the degree of impairment in the affected leg as measured by the ankle - brachial index...
this randomized trial proposed to determine if there were differences in calf muscle sto2 parameters in patients before and after 12 weeks of a traditional walking or walking - with - poles exercise program . data were collected on 85 patients who were randomized to a traditional walking program ( n = 40 ) or walking -...
[ "access to automated dna sequencing technology has made possible the rapid generation and analysis of gene transcripts expressed in organisms via expressed sequence tags ( ests ) . this information has helped to identify those genes expressed in particular stages of development and in specialized tissues or organs ...
backgroundmost organisms have developed ways to recognize and interact with other species . symbiotic interactions range from pathogenic to mutualistic . some molecular mechanisms of interspecific interaction are well understood , but many remain to be discovered . expressed sequence tags ( ests ) from cultures of inte...
[ "the transition - metal - catalyzed \n amination of aryl halides has become \n one of the most powerful methods to construct arylamines . the development of methods to couple aryl halides \n with amines has been studied extensively in the past decade . palladium - catalyzed reactions occur with a broad scope of bot...
first - row metal complexes often undergo undesirable one - electron redox processes during two - electron steps of catalytic cycles . we report the amination of aryl chlorides and bromides with primary aliphatic amines catalyzed by a well - defined , single - component nickel precursor ( binap)ni(2-nc - ph )...
[ "children diagnosed with jia were referred by pediatricians to our immuno - ophthalmology unit for ophthalmic examination . children 10 years old or younger presenting to our clinic with intraocular inflammation were referred for pediatric consult to verify a possible jia association . included in this study is a c...
objective : assess the incidence of intraocular inflammation ( uveitis ) and ocular complications in children with various types of jia in a single cohort of patients.patients:included are 172 children ( 35 boys and 137 girls ) diagnosed with jia . all underwent thorough initial ophthalmologic examination and were foll...
[ "increasing cytosolic calcium ion ( ca ) concentration is essential for the contraction of smooth muscle cells . the increase results from the influx of ca through the plasma membrane and release of ca from intracellular stores , mainly the sarcoplasmic reticulum ( sr ) [ 14 ] . phenylephrine ( pe ) or angiotensin ...
contraction of vascular smooth muscle cells depends on the induction of cytosolic calcium ion ( ca2 + ) due to either ca2 + influx through voltage - gated ca2 + channels or to receptor - mediated ca2 + release from the sarcoplasmic reticulum . the present study investigated the vasorelaxation effect of cinnamomi ramulu...
[ "after an information campaign in horse journals and at meetings , 278 samples of maple tree leaves , sprouts , and seeds collected by horse owners in 2014 were sent to utrecht university ( uu ) and rikiltwageningen ur ( figs 1 , 2 , 3 ) . the samples were taken from the ground , packed in plastic , and immediately...
backgroundatypical myopathy ( am ) in horses is caused by the plant toxin hypoglycin a , which in europe typically is found in the sycamore maple tree ( acer pseudoplatanus ) . owners are concerned about whether their horses are in danger if they graze near maple trees.hypothesis/objectivesto measure hypoglycin a in th...
[ "cell migration requires the rearrangement of adhesions and cytoskeleton in response to extracellular stimuli to form a leading edge that allows directed locomotion . in most cell types , migration - related adhesive structures are composed of integrin heterodimers and intracellular associated proteins clustered in...
summarythe wiskott - aldrich syndrome protein ( wasp ) is an adaptor protein that is essential for podosome formation in hematopoietic cells [ 1 ] . given that 80% of identified wiskott - aldrich syndrome patients result from mutations in the binding site for wasp - interacting - protein ( wip ) [ 2 ] , we examined the...
[ "ventriculoperitoneal ( vp ) shunting is commonly utilized as a diversion procedure for patients with hydrocephalus . multiple techniques for initial placement of the catheters have been described , including conventional minilaparotomy , peel - away introducer sheaths , as well as full laparoscopic approaches . vp...
a 31-year - old female with a history of pseudotumor cerebri presented with headache and abdominal discomfort after placement of a ventriculoperitoneal ( vp ) shunt . the vp shunt was placed after prior failure and revision of a lumbar peritoneal shunt . computed tomography demonstrated shunt migration into the subcuta...
[ "ventilator - associated pneumonia ( vap ) is defined as pneumonia occurring more than 48 hours after patients have been intubated and received mechanical ventilation . vap is the most common nosocomial infection in the intensive care unit ( icu ) with an incidence ranging from 8% to 28% in intubated mechanically v...
background : ventilator - associated pneumonia ( vap ) is a common complication of ventilatory support for patients with acute respiratory failure and is associated with increased morbidity and mortality.aim of the study : the present study was undertaken to do quantitative cultures of aerobic bacteria , perform the an...
[ "alpha1-adrenergic receptors ( 1-ars ) are a heterogeneous family of g - protein - coupled receptors that present in most human and animal tissues , and there are considerable variations in the expression levels of 1-ar subtypes in various tissues of different species [ 14 ] . 1-ars play important roles in regulati...
alpha1d - adrenergic receptor ( 1d - ar ) plays important roles in regulating physiological and pathological responses mediated by catecholamines , particularly in the cardiovascular and urinary systems . the present study was designed to investigate the expression profile of 1d - ar in the diabetic kidneys and its mod...
[ "while the occurrence of dental caries has decreased during the last decades , researchers had focused on non - carious lesions , including erosion \n . dental erosion is an acid - induced tooth loss not involving microorganisms caused by external and/or internal acids \n . recent studies indicate a meaningful incr...
objective this in vitro study assessed the anti - erosive effect of experimental mouthrinses containing tif4 and naf on dentin erosive loss.material and methods bovine dentin specimens were randomly allocated into the groups ( n=15 ) : 1 ) sncl2/naf / amf ( erosion protection/gaba , ph 4.5 , positive control ) ; 2 ) ex...
[ "allergic diseases are among the most common chronic diseases throughout the world and the prevalence of atopic diseases in childhood has significantly increased during the past several decades [ 2 , 3 ] . although there is a general consensus on the importance of a genetic predisposition for atopic diseases , on...
background and objective . allergy - like symptoms such as wheezing and eczema are common in young children and an early diagnosis is important to initiate correct management . the objective of this study was to evaluate the diagnostic performance of phadiatop infant , an in vitro test for determination of early sens...
[ "mainly for safety reasons , many patients and their families are looking for a seizure detection system that is efficient , comfortable , and easy to use . this implies that such a system should have a high detection sensitivity ( detect as many seizures as possible ) and low false alarm rate ; it should be unobtr...
purposethe aim of our study was to test the efficacy of the varia system ( video , accelerometry , and radar - induced activity recording ) and validation of accelerometry - based detection algorithms for nocturnal tonic clonic and clonic seizures developed by our team.methodswe present the results of two patients wit...
[ "angiomyolipoma ( aml ) is a benign mesenchymal tumour consisting of varying amounts of mature adipose tissue , smooth muscle , and thick walled blood vessels . it is relatively rare benign tumour appearing in about 0.3% of general population and accounts for 3% of solid renal masses . extra renal amls ( eramls ) a...
angiomyolipoma ( aml ) is a rare mesenchymal tumour arising from perivascular epithelioid cells . it is most commonly seen in kidney , but rarely aml can arise in extra renal sites . adrenal aml is a very rare clinical entity , and very few cases have been reported so far . we present our experience with a 43-year - ol...
[ "a 67-year - old male presented to the emergency eye centre ( eec ) complaining of a painful right eye of 5-day duration . clinical examination revealed a visual acuity ( va ) of 6/9 with minimal conjunctival injection , anterior chamber ( ac ) cells 1 + and posterior synechiae ( ps ) . a diagnosis of anterior uvei...
a 67-year - old former gold miner with rheumatoid arthritis , treated with steroids and methotrexate , presented to eye casualty with a painful right eye . examination revealed an anterior uveitis and despite an initial response to topical steroids , the intraocular inflammation worsened with anterior and posterior uve...
[ "in 1978 , primary health care was seen as the solution to the inadequate illness management systems that had developed throughout the world . it was hoped that phc would address some of the major inequalities in health that were observed by a balanced system of treatment and disease prevention . the world health o...
background : most countries use educated nurses called nurse practitioners ( nps ) besides the family physicians for diagnosis , treatment , and specifically health education of the family . the main goal of this study was to redefine the role of nps for better use of their capabilities in the so - called family phy...
[ "despite advancements in renal replacement therapy , acute kidney injury ( aki ) is a frequent complication with severe implications for the critically ill patient . published mortality rates for intensive care unit patients with aki range between 30 and 70% , and aki alone remains an independent risk factor for mo...
acute kidney injury ( aki ) is a common complication during inpatient hospitalization , and clinical outcomes remain poor despite advancements in renal replacement therapy . aki in the setting of multiple organ failure ( mof ) remains a formidable challenge to clinicians and incurs an unacceptably high mortality rate ....