accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q92759 | TF2H4_HUMAN | TFIIH basal transcription factor complex p52 subunit | Homo | <M><E><S><T><P><S><R><G><L><N><R><V><H><L><Q><C><R><N><L><Q><E><F><L><G><G><L><S><P><G><V><L><D><R><L><Y><G><H><P><A><T><C><L><A><V><F><R><E><L><P><S><L><A><K><N><W><V><M><R><M><L><F><L><E><Q><P><L><P><Q><A><A><V><A><L><W><V><K><K><E><F><S><K><A><Q><E><E><S><T><G><L><L><S><G><L><R><I><W><H><T><Q><L><L><P><G><G><L><Q><G... | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allo... | Q92759 |
Q9H5K3 | SG196_HUMAN | Sugen kinase 196 | Homo | <M><E><K><Q><P><Q><N><S><R><R><G><L><A><P><R><E><V><P><P><A><V><G><L><L><L><I><M><A><L><M><N><T><L><L><Y><L><C><L><D><H><F><F><I><A><P><R><Q><S><T><V><D><P><T><H><C><P><Y><G><H><F><R><I><G><Q><M><K><N><C><S><P><W><L><S><C><E><E><L><R><T><E><V><R><Q><L><K><R><V><G><E><G><A><V><K><R><V><F><L><S><E><W><K><E><H><K><V><A><L... | Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-... | Q9H5K3 |
Q99717 | SMAD5_HUMAN | SMAD family member 5 | Homo | <M><T><S><M><A><S><L><F><S><F><T><S><P><A><V><K><R><L><L><G><W><K><Q><G><D><E><E><E><K><W><A><E><K><A><V><D><A><L><V><K><K><L><K><K><K><K><G><A><M><E><E><L><E><K><A><L><S><S><P><G><Q><P><S><K><C><V><T><I><P><R><S><L><D><G><R><L><Q><V><S><H><R><K><G><L><P><H><V><I><Y><C><R><V><W><R><W><P><D><L><Q><S><H><H><E><L><K><P><L... | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).<BOP> | Q99717 |
Q07343 | PDE4B_HUMAN | PDE32 | Homo | <M><K><K><S><R><S><V><M><T><V><M><A><D><D><N><V><K><D><Y><F><E><C><S><L><S><K><S><Y><S><S><S><S><N><T><L><G><I><D><L><W><R><G><R><R><C><C><S><G><N><L><Q><L><P><P><L><S><Q><R><Q><S><E><R><A><R><T><P><E><G><D><G><I><S><R><P><T><T><L><P><L><T><T><L><P><S><I><A><I><T><T><V><S><Q><E><C><F><D><V><E><N><G><P><S><P><G><R><S><P... | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes . May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.<BOP> | Q07343 |
Q05513 | KPCZ_HUMAN | nPKC-zeta | Homo | <M><P><S><R><T><G><P><K><M><E><G><S><G><G><R><V><R><L><K><A><H><Y><G><G><D><I><F><I><T><S><V><D><A><A><T><T><F><E><E><L><C><E><E><V><R><D><M><C><R><L><H><Q><Q><H><P><L><T><L><K><W><V><D><S><E><G><D><P><C><T><V><S><S><Q><M><E><L><E><E><A><F><R><L><A><R><Q><C><R><D><E><G><L><I><I><H><V><F><P><S><T><P><E><Q><P><G><L><P><C... | Involved in late synaptic long term potention phase in CA1 hippocampal cells and long term memory maintenance.<BOP> | Q05513 |
Q8WXF3 | REL3_HUMAN | Relaxin-3 A chain | Homo | <M><A><R><Y><M><L><L><L><L><L><A><V><W><V><L><T><G><E><L><W><P><G><A><E><A><R><A><A><P><Y><G><V><R><L><C><G><R><E><F><I><R><A><V><I><F><T><C><G><G><S><R><W><R><R><S><D><I><L><A><H><E><A><M><G><D><T><F><P><D><A><D><A><D><E><D><S><L><A><G><E><L><D><E><A><M><G><S><S><E><W><L><A><L><T><K><S><P><Q><A><F><Y><R><G><R><P><S><W... | May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4.<BOP> | Q8WXF3 |
Q3SXZ3 | ZN718_HUMAN | Zinc finger protein 718 | Homo | <M><E><L><L><T><F><K><D><V><A><I><E><F><S><P><E><E><W><K><C><L><D><T><S><Q><Q><N><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><S><L><G><V><S><I><S><N><P><D><L><V><T><S><L><E><Q><R><K><E><P><Y><N><L><K><I><H><E><T><A><A><R><P><P><A><V><C><S><H><F><T><Q><N><L><W><T><V><Q><G><I><E><D><S><F><H><K><L><I><P><K><G><H><E><K><R><G... | May be involved in transcriptional regulation.<BOP> | Q3SXZ3 |
P21462 | FPR1_HUMAN | N-formylpeptide chemoattractant receptor | Homo | <M><E><T><N><S><S><L><P><T><N><I><S><G><G><T><P><A><V><S><A><G><Y><L><F><L><D><I><I><T><Y><L><V><F><A><V><T><F><V><L><G><V><L><G><N><G><L><V><I><W><V><A><G><F><R><M><T><H><T><V><T><T><I><S><Y><L><N><L><A><V><A><D><F><C><F><T><S><T><L><P><F><F><M><V><R><K><A><M><G><G><H><W><P><F><G><W><F><L><C><K><F><V><F><T><I><V><D><I... | High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors . Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release . This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second m... | P21462 |
O95944 | NCTR2_HUMAN | Natural killer cell p44-related protein | Homo | <M><A><W><R><A><L><H><P><L><L><L><L><L><L><L><F><P><G><S><Q><A><Q><S><K><A><Q><V><L><Q><S><V><A><G><Q><T><L><T><V><R><C><Q><Y><P><P><T><G><S><L><Y><E><K><K><G><W><C><K><E><A><S><A><L><V><C><I><R><L><V><T><S><S><K><P><R><T><M><A><W><T><S><R><F><T><I><W><D><D><P><D><A><G><F><F><T><V><T><M><T><D><L><R><E><E><D><S><G><H><Y... | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.<BOP> | O95944 |
O14904 | WNT9A_HUMAN | Protein Wnt-14 | Homo | <M><L><D><G><S><P><L><A><R><W><L><A><A><A><F><G><L><T><L><L><L><A><A><L><R><P><S><A><A><Y><F><G><L><T><G><S><E><P><L><T><I><L><P><L><T><L><E><P><E><A><A><A><Q><A><H><Y><K><A><C><D><R><L><K><L><E><R><K><Q><R><R><M><C><R><R><D><P><G><V><A><E><T><L><V><E><A><V><S><M><S><A><L><E><C><Q><F><Q><F><R><F><E><R><W><N><C><T><L><E... | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. P... | O14904 |
Q7Z6L0 | PRRT2_HUMAN | Dispanin subfamily B member 3 | Homo | <M><A><A><S><S><S><E><I><S><E><M><K><G><V><E><E><S><P><K><V><P><G><E><G><P><G><H><S><E><A><E><T><G><P><P><Q><V><L><A><G><V><P><D><Q><P><E><A><P><Q><P><G><P><N><T><T><A><A><P><V><D><S><G><P><K><A><G><L><A><P><E><T><T><E><T><P><A><G><A><S><E><T><A><Q><A><T><D><L><S><L><S><P><G><G><E><S><K><A><N><C><S><P><E><D><P><C><Q><E... | As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE... | Q7Z6L0 |
Q9NQY0 | BIN3_HUMAN | Bridging integrator 3 | Homo | <M><S><W><I><P><F><K><I><G><Q><P><K><K><Q><I><V><P><K><T><V><E><R><D><F><E><R><E><Y><G><K><L><Q><Q><L><E><E><Q><T><R><R><L><Q><K><D><M><K><K><S><T><D><A><D><L><A><M><S><K><S><A><V><K><I><S><L><D><L><L><S><N><P><L><C><E><Q><D><Q><D><L><L><N><M><V><T><A><L><D><T><A><M><K><R><M><D><A><F><N><Q><E><K><V><N><Q><I><Q><K><T><V... | Involved in cytokinesis and septation where it has a role in the localization of F-actin.<BOP> | Q9NQY0 |
Q5VU69 | CP141_HUMAN | Cilia- and flagella-associated protein 141 | Homo | <M><S><V><E><K><M><T><K><V><E><E><S><F><Q><K><A><M><G><L><K><K><T><V><D><R><W><R><N><S><H><T><H><C><L><W><Q><M><A><L><G><Q><R><R><N><P><Y><A><T><L><R><M><Q><D><T><M><V><Q><E><L><A><L><A><K><K><Q><L><L><M><V><R><Q><A><A><L><H><Q><L><F><E><K><E><H><Q><Q><Y><Q><Q><E><L><N><Q><M><G><K><A><F><Y><V><E><R><F> | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.<BOP> | Q5VU69 |
Q9BRR9 | RHG09_HUMAN | Rho-type GTPase-activating protein 9 | Homo | <M><L><S><S><R><W><W><P><S><S><W><G><I><L><G><L><G><P><R><S><P><P><R><G><S><Q><L><C><A><L><Y><A><F><T><Y><T><G><A><D><G><Q><Q><V><S><L><A><E><G><D><R><F><L><L><L><R><K><T><N><S><D><W><W><L><A><R><R><L><E><A><P><S><T><S><R><P><I><F><V><P><A><A><Y><M><I><E><E><S><I><P><S><Q><S><P><T><T><V><I><P><G><Q><L><L><W><T><P><G><P... | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphat... | Q9BRR9 |
P09326 | CD48_HUMAN | TCT.1 | Homo | <M><C><S><R><G><W><D><S><C><L><A><L><E><L><L><L><L><P><L><S><L><L><V><T><S><I><Q><G><H><L><V><H><M><T><V><V><S><G><S><N><V><T><L><N><I><S><E><S><L><P><E><N><Y><K><Q><L><T><W><F><Y><T><F><D><Q><K><I><V><E><W><D><S><R><K><S><K><Y><F><E><S><K><F><K><G><R><V><R><L><D><P><Q><S><G><A><L><Y><I><S><K><V><Q><K><E><D><N><S><T><Y... | Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation . Participates in T-cell signaling transduction by associating with CD2 and efficiently bri... | P09326 |
Q9UHD9 | UBQL2_HUMAN | Ubiquitin-like product Chap1/Dsk2 | Homo | <M><A><E><N><G><E><S><S><G><P><P><R><P><S><R><G><P><A><A><A><Q><G><S><A><A><A><P><A><E><P><K><I><I><K><V><T><V><K><T><P><K><E><K><E><E><F><A><V><P><E><N><S><S><V><Q><Q><F><K><E><A><I><S><K><R><F><K><S><Q><T><D><Q><L><V><L><I><F><A><G><K><I><L><K><D><Q><D><T><L><I><Q><H><G><I><H><D><G><L><T><V><H><L><V><I><K><S><Q><N><R... | Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation b... | Q9UHD9 |
Q9H910 | JUPI2_HUMAN | Hematological and neurological expressed 1-like protein | Homo | <M><F><Q><V><P><D><S><E><G><G><R><A><G><S><R><A><M><K><P><P><G><G><E><S><S><N><L><F><G><S><P><E><E><A><T><P><S><S><R><P><N><R><M><A><S><N><I><F><G><P><T><E><E><P><Q><N><I><P><K><R><T><N><P><P><G><G><K><G><S><G><I><F><D><E><S><T><P><V><Q><T><R><Q><H><L><N><P><P><G><G><K><T><S><D><I><F><G><S><P><V><T><A><T><S><R><L><A><H... | (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2.<BOP> | Q9H910 |
Q14507 | EP3A_HUMAN | Human epididymis-specific protein 3-alpha | Homo | <M><T><S><S><L><K><I><W><G><I><L><L><A><L><L><C><I><L><C><R><L><C><V><Y><S><N><N><I><Y><W><R><E><F><I><K><L><H><Y><L><S><P><S><R><E><F><K><E><Y><K><C><D><V><L><M><R><E><K><E><A><L><K><G><K><S><F><H><M><F><I><Y><S><L><W><F><K><I><Q><R><A><C><I><N><E><K><G><S><D><R><Y><R><N><A><Y><V><W><A><P><G><A><L><K><V><L><E><C><H><W... | Possible function in sperm maturation.<BOP> | Q14507 |
Q9NV72 | ZN701_HUMAN | Zinc finger protein 701 | Homo | <M><G><F><L><H><V><G><Q><D><G><L><E><L><P><T><S><G><D><P><P><A><S><A><S><Q><S><A><G><I><T><G><V><S><H><R><T><Q><P><P><C><F><E><G><L><T><S><K><D><L><V><R><E><E><K><T><R><K><R><K><R><K><A><K><E><S><G><M><A><L><L><Q><G><L><L><T><F><R><D><V><A><I><E><F><S><Q><E><E><W><K><C><L><D><P><A><Q><R><T><L><Y><R><D><V><M><L><E><N><Y... | May be involved in transcriptional regulation.<BOP> | Q9NV72 |
C0HLV8 | MP31_HUMAN | Micropeptide 31 | Homo | <M><W><R><D><S><L><C><A><A><A><G><Y><A><L><G><A><G><T><R><L><R><S><V><L><S><S><R><K><L><Q><P> | Inhibits lactate dehydrogenase (LDH)-mediated conversion of lactate to pyruvate in mitochondria by competing with mitochondrial LDH for binding to NAD(+) . Also inhibits cellular lactate utilization .<BOP> | C0HLV8 |
A6NK02 | TRI75_HUMAN | Tripartite motif-containing protein 75 | Homo | <M><A><V><A><A><A><L><T><G><L><Q><A><E><A><K><C><S><I><C><L><D><Y><L><S><D><P><V><T><I><E><C><G><H><N><F><C><R><S><C><I><Q><Q><S><W><L><D><L><Q><E><L><F><P><C><P><V><C><R><H><Q><C><Q><E><G><H><F><R><S><N><T><Q><L><G><R><M><I><E><I><A><K><L><L><Q><S><T><K><S><N><K><R><K><Q><E><E><T><T><L><C><E><K><H><N><Q><P><L><S><V><F... | May play a role in female meiosis.<BOP> | A6NK02 |
Q5J8X5 | M4A13_HUMAN | Testis-expressed transmembrane protein 4 | Homo | <M><I><G><I><F><H><I><F><M><W><Y><F><L><L><V><L><Y><M><G><Q><I><K><G><A><F><G><T><Y><E><P><V><T><Y><K><T><G><C><T><L><W><G><I><F><F><I><I><A><G><V><F><L><I><R><V><T><K><Y><P><T><R><S><G><I><I><S><T><L><I><I><N><I><I><C><I><I><T><T><I><T><A><V><T><L><T><I><I><E><L><S><H><F><N><S><V><S><Y><R><N><Y><G><Q><A><K><L><G><R><E... | May be involved in signal transduction as a component of a multimeric receptor complex.<BOP> | Q5J8X5 |
Q9NP08 | HMX1_HUMAN | Homeobox protein H6 | Homo | <M><P><D><E><L><T><E><P><G><R><A><T><P><A><R><A><S><S><F><L><I><E><N><L><L><A><A><E><A><K><G><A><G><R><A><T><Q><G><D><G><S><R><E><D><E><E><E><D><D><D><D><P><E><D><E><D><A><E><Q><A><R><R><R><R><L><Q><R><R><R><Q><L><L><A><G><T><G><P><G><G><E><A><R><A><R><A><L><L><G><P><G><A><L><G><L><G><P><R><P><P><P><G><P><G><P><P><F><A... | DNA-binding protein that binds to the 5'-CAAG-3' core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear.<BOP> | Q9NP08 |
Q99543 | DNJC2_HUMAN | DnaJ homolog subfamily C member 2, N-terminally processed | Homo | <M><L><L><L><P><S><A><A><D><G><R><G><T><A><I><T><H><A><L><T><S><A><S><T><L><C><Q><V><E><P><V><G><R><W><F><E><A><F><V><K><R><R><N><R><N><A><S><A><S><F><Q><E><L><E><D><K><K><E><L><S><E><E><S><E><D><E><E><L><Q><L><E><E><F><P><M><L><K><T><L><D><P><K><D><W><K><N><Q><D><H><Y><A><V><L><G><L><G><H><V><R><Y><K><A><T><Q><R><Q><I... | Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPas... | Q99543 |
Q9UN42 | AT1B4_HUMAN | X/potassium-transporting ATPase subunit beta-m | Homo | <M><R><R><Q><L><R><S><R><R><A><P><S><F><P><Y><S><Y><R><Y><R><L><D><D><P><D><E><A><N><Q><N><Y><L><A><D><E><E><E><E><A><E><E><E><A><R><V><T><V><V><P><K><S><E><E><E><E><E><E><E><E><K><E><E><E><E><E><E><E><K><E><E><E><E><G><Q><G><Q><P><T><G><N><A><W><W><Q><K><L><Q><I><M><S><E><Y><L><W><D><P><E><R><R><M><F><L><A><R><T><G><Q... | May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit.<BOP> | Q9UN42 |
A0A075B6I3 | LVK55_HUMAN | Probable non-functional immunoglobulin lambda variable 11-55 | Homo | <M><A><L><T><P><L><L><L><L><L><L><S><H><C><T><G><S><L><S><R><P><V><L><T><Q><P><P><S><L><S><A><S><P><G><A><T><A><R><L><P><C><T><L><S><S><D><L><S><V><G><G><K><N><M><F><W><Y><Q><Q><K><L><G><S><S><P><R><L><F><L><Y><H><Y><S><D><S><D><K><Q><L><G><P><G><V><P><S><R><V><S><G><S><K><E><T><S><S><N><T><A><F><L><L><I><S><G><L><Q><P... | Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains . Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved ... | A0A075B6I3 |
Q6GMV1 | ALG1L_HUMAN | Putative glycosyltransferase ALG1-like | Homo | <M><E><R><S><A><F><M><E><L><D><A><G><S><R><L><V><M><H><L><R><E><W><P><A><L><L><V><S><S><T><G><W><T><E><F><E><Q><L><T><L><D><G><H><N><L><P><S><L><V><C><V><I><T><G><S><V><D><L><G><V><C><L><H><M><S><S><S><G><L><D><L><P><M><K><V><V><D><M><F><G><C><C><L><P><V><C><A><V><N><F><K><C><L><H><E><L><V><K><H><E><E><N><G><L><V><F><E... | Putative glycosyltransferase.<BOP> | Q6GMV1 |
Q6UX15 | LAYN_HUMAN | Layilin | Homo | <M><R><P><G><T><A><L><Q><A><V><L><L><A><V><L><L><V><G><L><R><A><A><T><G><R><L><L><S><A><S><D><L><D><L><R><G><G><Q><P><V><C><R><G><G><T><Q><R><P><C><Y><K><V><I><Y><F><H><D><T><S><R><R><L><N><F><E><E><A><K><E><A><C><R><R><D><G><G><Q><L><V><S><I><E><S><E><D><E><Q><K><L><I><E><K><F><I><E><N><L><L><P><S><D><G><D><F><W><I><G... | Receptor for hyaluronate.<BOP> | Q6UX15 |
Q6UXK2 | ISLR2_HUMAN | Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein | Homo | <M><F><P><L><R><A><L><W><L><V><W><A><L><L><G><V><A><G><S><C><P><E><P><C><A><C><V><D><K><Y><A><H><Q><F><A><D><C><A><Y><K><E><L><R><E><V><P><E><G><L><P><A><N><V><T><T><L><S><L><S><A><N><K><I><T><V><L><R><R><G><A><F><A><D><V><T><Q><V><T><S><L><W><L><A><H><N><E><V><R><T><V><E><P><G><A><L><A><V><L><S><Q><L><K><N><L><D><L><S... | Required for axon extension during neural development.<BOP> | Q6UXK2 |
Q13242 | SRSF9_HUMAN | Splicing factor, arginine/serine-rich 9 | Homo | <M><S><G><W><A><D><E><R><G><G><E><G><D><G><R><I><Y><V><G><N><L><P><T><D><V><R><E><K><D><L><E><D><L><F><Y><K><Y><G><R><I><R><E><I><E><L><K><N><R><H><G><L><V><P><F><A><F><V><R><F><E><D><P><R><D><A><E><D><A><I><Y><G><R><N><G><Y><D><Y><G><Q><C><R><L><R><V><E><F><P><R><T><Y><G><G><R><G><G><W><P><R><G><G><R><N><G><P><P><T><R... | Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.<BOP> | Q13242 |
Q9H5U6 | ZCHC4_HUMAN | Zinc finger CCHC domain-containing protein 4 | Homo | <M><A><A><S><R><N><G><F><E><A><V><E><A><E><G><S><A><G><C><R><G><S><S><G><M><E><V><V><L><P><L><D><P><A><V><P><A><P><L><C><P><H><G><P><T><L><L><F><V><K><V><T><Q><G><K><E><E><T><R><R><F><Y><A><C><S><A><C><R><D><R><K><D><C><N><F><F><Q><W><E><D><E><K><L><S><G><A><R><L><A><A><R><E><A><H><N><R><R><C><Q><P><P><L><S><R><T><Q><C... | rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA . N6-methylation of adenine(4220) in 28S rRNA is required for translation .<BOP> | Q9H5U6 |
Q96EQ8 | RN125_HUMAN | T-cell RING activation protein 1 | Homo | <M><G><S><V><L><S><T><D><S><G><K><S><A><P><A><S><A><T><A><R><A><L><E><R><R><R><D><P><E><L><P><V><T><S><F><D><C><A><V><C><L><E><V><L><H><Q><P><V><R><T><R><C><G><H><V><F><C><R><S><C><I><A><T><S><L><K><N><N><K><W><T><C><P><Y><C><R><A><Y><L><P><S><E><G><V><P><A><T><D><V><A><K><R><M><K><S><E><Y><K><N><C><A><E><C><D><T><L><V... | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53 . Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I... | Q96EQ8 |
Q9BU64 | CENPO_HUMAN | Interphase centromere complex protein 36 | Homo | <M><E><Q><A><N><P><L><R><P><D><G><E><S><K><G><G><V><L><A><H><L><E><R><L><E><T><Q><V><S><R><S><R><K><Q><S><E><E><L><Q><S><V><Q><A><Q><E><G><A><L><G><T><K><I><H><K><L><R><R><L><R><D><E><L><R><A><V><V><R><H><R><R><A><S><V><K><A><C><I><A><N><V><E><P><N><Q><T><V><E><I><N><E><Q><E><A><L><E><E><K><L><E><N><V><K><A><I><L><Q><A... | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. M... | Q9BU64 |
Q96MA6 | KAD8_HUMAN | ATP-AMP transphosphorylase 8 | Homo | <M><D><A><T><I><A><P><H><R><I><P><P><E><M><P><Q><Y><G><E><E><N><H><I><F><E><L><M><Q><N><M><L><E><Q><L><L><I><H><Q><P><E><D><P><I><P><F><M><I><Q><H><L><H><R><D><N><D><N><V><P><R><I><V><I><L><G><P><P><A><S><G><K><T><T><I><A><M><W><L><C><K><H><L><N><S><S><L><L><T><L><E><N><L><I><L><N><E><F><S><Y><T><A><T><E><A><R><R><L><Y... | Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.<BOP> | Q96MA6 |
P49448 | DHE4_HUMAN | Glutamate dehydrogenase 2, mitochondrial | Homo | <M><Y><R><Y><L><A><K><A><L><L><P><S><R><A><G><P><A><A><L><G><S><A><A><N><H><S><A><A><L><L><G><R><G><R><G><Q><P><A><A><A><S><Q><P><G><L><A><L><A><A><R><R><H><Y><S><E><L><V><A><D><R><E><D><D><P><N><F><F><K><M><V><E><G><F><F><D><R><G><A><S><I><V><E><D><K><L><V><K><D><L><R><T><Q><E><S><E><E><Q><K><R><N><R><V><R><G><I><L><R... | Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.<BOP> | P49448 |
Q9H7B4 | SMYD3_HUMAN | Zinc finger MYND domain-containing protein 1 | Homo | <M><E><P><L><K><V><E><K><F><A><T><A><K><R><G><N><G><L><R><A><V><T><P><L><R><P><G><E><L><L><F><R><S><D><P><L><A><Y><T><V><C><K><G><S><R><G><V><V><C><D><R><C><L><L><G><K><E><K><L><M><R><C><S><Q><C><R><V><A><K><Y><C><S><A><K><C><Q><K><K><A><W><P><D><H><K><R><E><C><K><C><L><K><S><C><K><P><R><Y><P><P><D><S><V><R><L><L><G><R... | Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation . Also methylates 'Lys-5' of histone H4 . Plays an important role in transcriptional activation as a member of an RNA polymerase complex . Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3'... | Q9H7B4 |
P53667 | LIMK1_HUMAN | LIM domain kinase 1 | Homo | <M><R><L><T><L><L><C><C><T><W><R><E><E><R><M><G><E><E><G><S><E><L><P><V><C><A><S><C><G><Q><R><I><Y><D><G><Q><Y><L><Q><A><L><N><A><D><W><H><A><D><C><F><R><C><C><D><C><S><A><S><L><S><H><Q><Y><Y><E><K><D><G><Q><L><F><C><K><K><D><Y><W><A><R><Y><G><E><S><C><H><G><C><S><E><Q><I><T><K><G><L><V><M><V><A><G><E><L><K><Y><H><P><E... | Has a dominant negative effect on actin cytoskeletal changes. Required for atypical chemokine receptor ACKR2-induced phosphorylation of cofilin (CFL1).<BOP> | P53667 |
P20671 | H2A1D_HUMAN | Histone H2A/g | Homo | <M><S><G><R><G><K><Q><G><G><K><A><R><A><K><A><K><T><R><S><S><R><A><G><L><Q><F><P><V><G><R><V><H><R><L><L><R><K><G><N><Y><S><E><R><V><G><A><G><A><P><V><Y><L><A><A><V><L><E><Y><L><T><A><E><I><L><E><L><A><G><N><A><A><R><D><N><K><K><T><R><I><I><P><R><H><L><Q><L><A><I><R><N><D><E><E><L><N><K><L><L><G><K><V><T><I><A><Q><G><G... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | P20671 |
Q68G74 | LHX8_HUMAN | LIM/homeobox protein Lhx8 | Homo | <M><Q><I><L><S><R><C><Q><G><L><M><S><E><E><C><G><R><T><T><A><L><A><A><G><R><T><R><K><G><A><G><E><E><G><L><V><S><P><E><G><A><G><D><E><D><S><C><S><S><S><A><P><L><S><P><S><S><S><P><R><S><M><A><S><G><S><G><C><P><P><G><K><C><V><C><N><S><C><G><L><E><I><V><D><K><Y><L><L><K><V><N><D><L><C><W><H><V><R><C><L><S><C><S><V><C><R><T... | Transcription factor involved in differentiation of certain neurons and mesenchymal cells.<BOP> | Q68G74 |
Q6UW01 | CBLN3_HUMAN | Cerebellin-3 | Homo | <M><L><G><A><K><P><H><W><L><P><G><P><L><H><S><P><G><L><P><L><V><L><V><L><L><A><L><G><A><G><W><A><Q><E><G><S><E><P><V><L><L><E><G><E><C><L><V><V><C><E><P><G><R><A><A><A><G><G><P><G><G><A><A><L><G><E><A><P><P><G><R><V><A><F><A><A><V><R><S><H><H><H><E><P><A><G><E><T><G><N><G><T><S><G><A><I><Y><F><D><Q><V><L><V><N><E><G><G... | May be involved in synaptic functions in the CNS.<BOP> | Q6UW01 |
Q9UGQ3 | GTR6_HUMAN | Glucose transporter type 6 | Homo | <M><Q><E><P><L><L><G><A><E><G><P><D><Y><D><T><F><P><E><K><P><P><P><S><P><G><D><R><A><R><V><G><T><L><Q><N><K><R><V><F><L><A><T><F><A><A><V><L><G><N><F><S><F><G><Y><A><L><V><Y><T><S><P><V><I><P><A><L><E><R><S><L><D><P><D><L><H><L><T><K><S><Q><A><S><W><F><G><S><V><F><T><L><G><A><A><A><G><G><L><S><A><M><I><L><N><D><L><L><G... | Probable sugar transporter that acts as a regulator of glycolysis in macrophages (Probable). Does not transport glucose .<BOP> | Q9UGQ3 |
Q9BUR5 | MIC26_HUMAN | Protein FAM121B | Homo | <M><F><K><V><I><Q><R><S><V><G><P><A><S><L><S><L><L><T><F><K><V><Y><A><A><P><K><K><D><S><P><P><K><N><S><V><K><V><D><E><L><S><L><Y><S><V><P><E><G><Q><S><K><Y><V><E><E><A><R><S><Q><L><E><E><S><I><S><Q><L><R><H><Y><C><E><P><Y><T><T><W><C><Q><E><T><Y><S><Q><T><K><P><K><M><Q><S><L><V><Q><W><G><L><D><S><Y><D><Y><L><Q><N><A><P... | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function . C... | Q9BUR5 |
Q400G9 | AMZ1_HUMAN | Archeobacterial metalloproteinase-like protein 1 | Homo | <M><L><Q><C><R><P><A><Q><E><F><S><F><G><P><R><A><L><K><D><A><L><V><S><T><D><A><A><L><Q><Q><L><Y><V><S><A><F><S><P><A><E><R><L><F><L><A><E><A><Y><N><P><Q><R><T><L><F><C><T><L><L><I><R><T><G><F><D><W><L><L><S><R><P><E><A><P><E><D><F><Q><T><F><H><A><S><L><Q><H><R><K><P><R><L><A><R><K><H><I><Y><L><Q><P><I><D><L><S><E><E><P... | Probable zinc metalloprotease.<BOP> | Q400G9 |
Q6XYB7 | LBX2_HUMAN | Ladybird homeobox protein homolog 2 | Homo | <M><N><S><G><R><E><P><R><T><P><R><T><L><L><S><I><A><D><I><L><A><P><R><M><V><P><R><A><P><S><A><P><Q><L><P><E><S><G><P><G><P><T><S><P><L><C><A><L><E><E><L><T><S><K><T><F><R><G><L><D><A><R><A><L><Q><P><S><E><G><R><A><G><P><D><A><L><G><P><G><P><F><G><R><K><R><R><K><S><R><T><A><F><T><A><Q><Q><V><L><E><L><E><R><R><F><V><F><Q... | Transcription factor.<BOP> | Q6XYB7 |
P19971 | TYPH_HUMAN | TdRPase | Homo | <M><A><A><L><M><T><P><G><T><G><A><P><P><A><P><G><D><F><S><G><E><G><S><Q><G><L><P><D><P><S><P><E><P><K><Q><L><P><E><L><I><R><M><K><R><D><G><G><R><L><S><E><A><D><I><R><G><F><V><A><A><V><V><N><G><S><A><Q><G><A><Q><I><G><A><M><L><M><A><I><R><L><R><G><M><D><L><E><E><T><S><V><L><T><Q><A><L><A><Q><S><G><Q><Q><L><E><W><P><E><A... | Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP> | P19971 |
P02689 | MYP2_HUMAN | Peripheral myelin protein 2 | Homo | <M><S><N><K><F><L><G><T><W><K><L><V><S><S><E><N><F><D><D><Y><M><K><A><L><G><V><G><L><A><T><R><K><L><G><N><L><A><K><P><T><V><I><I><S><K><K><G><D><I><I><T><I><R><T><E><S><T><F><K><N><T><E><I><S><F><K><L><G><Q><E><F><E><E><T><T><A><D><N><R><K><T><K><S><I><V><T><L><Q><R><G><S><L><N><Q><V><Q><R><W><D><G><K><E><T><T><I><K><R... | May play a role in lipid transport protein in Schwann cells. May bind cholesterol.<BOP> | P02689 |
P51124 | GRAM_HUMAN | Natural killer cell granular protease | Homo | <M><E><A><C><V><S><S><L><L><V><L><A><L><G><A><L><S><V><G><S><S><F><G><T><Q><I><I><G><G><R><E><V><I><P><H><S><R><P><Y><M><A><S><L><Q><R><N><G><S><H><L><C><G><G><V><L><V><H><P><K><W><V><L><T><A><A><H><C><L><A><Q><R><M><A><Q><L><R><L><V><L><G><L><H><T><L><D><S><P><G><L><T><F><H><I><K><A><A><I><Q><H><P><R><Y><K><P><V><P><A... | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.<BOP> | P51124 |
P46092 | CCR10_HUMAN | G-protein coupled receptor 2 | Homo | <M><G><T><E><A><T><E><Q><V><S><W><G><H><Y><S><G><D><E><E><D><A><Y><S><A><E><P><L><P><E><L><C><Y><K><A><D><V><Q><A><F><S><R><A><F><Q><P><S><V><S><L><T><V><A><A><L><G><L><A><G><N><G><L><V><L><A><T><H><L><A><A><R><R><A><A><R><S><P><T><S><A><H><L><L><Q><L><A><L><A><D><L><L><L><A><L><T><L><P><F><A><A><A><G><A><L><Q><G><W><S... | Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.<BOP> | P46092 |
Q9BY32 | ITPA_HUMAN | Putative oncogene protein hlc14-06-p | Homo | <M><A><A><S><L><V><G><K><K><I><V><F><V><T><G><N><A><K><K><L><E><E><V><V><Q><I><L><G><D><K><F><P><C><T><L><V><A><Q><K><I><D><L><P><E><Y><Q><G><E><P><D><E><I><S><I><Q><K><C><Q><E><A><V><R><Q><V><Q><G><P><V><L><V><E><D><T><C><L><C><F><N><A><L><G><G><L><P><G><P><Y><I><K><W><F><L><E><K><L><K><P><E><G><L><H><Q><L><L><A><G><F... | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between ... | Q9BY32 |
A0PJE2 | DHR12_HUMAN | Short-chain dehydrogenase/reductase family 40C member 1 | Homo | <M><S><L><Y><R><S><V><V><W><F><A><K><G><L><R><E><Y><T><K><S><G><Y><E><S><A><C><K><D><F><V><P><H><D><L><E><V><Q><I><P><G><R><V><F><L><V><T><G><G><N><S><G><I><G><K><A><T><A><L><E><I><A><K><R><G><G><T><V><H><L><V><C><R><D><Q><A><P><A><E><D><A><R><G><E><I><I><R><E><S><G><N><Q><N><I><F><L><H><I><V><D><L><S><D><P><K><Q><I><W... | Putative oxidoreductase.<BOP> | A0PJE2 |
Q7Z7B8 | DB128_HUMAN | Defensin, beta 128 | Homo | <M><K><L><F><L><V><L><I><I><L><L><F><E><V><L><T><D><G><A><R><L><K><K><C><F><N><K><V><T><G><Y><C><R><K><K><C><K><V><G><E><R><Y><E><I><G><C><L><S><G><K><L><C><C><A><N><D><E><E><E><K><K><H><V><S><F><K><K><P><H><Q><H><S><G><E><K><L><S><V><L><Q><D><Y><I><I><L><P><T><I><T><I><F><T><V> | Has antibacterial activity.<BOP> | Q7Z7B8 |
Q6P531 | GGT6_HUMAN | Glutathione hydrolase 6 light chain | Homo | <M><E><R><A><E><E><P><V><V><Y><Q><K><L><L><P><W><E><P><S><L><E><S><E><E><E><V><E><E><E><E><T><S><E><A><L><V><L><N><P><R><R><H><Q><D><S><S><R><N><K><A><G><G><L><P><G><T><W><A><R><V><V><A><A><L><L><L><L><A><V><G><C><S><L><A><V><R><Q><L><Q><N><Q><G><R><S><T><G><S><L><G><S><V><A><P><P><P><G><G><H><S><H><G><P><G><V><Y><H><H... | Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors.<BOP> | Q6P531 |
O43548 | TGM5_HUMAN | Transglutaminase-5 | Homo | <M><A><Q><G><L><E><V><A><L><T><D><L><Q><S><S><R><N><N><V><R><H><H><T><E><E><I><T><V><D><H><L><L><V><R><R><G><Q><A><F><N><L><T><L><Y><F><R><N><R><S><F><Q><P><G><L><D><N><I><I><F><V><V><E><T><G><P><L><P><D><L><A><L><G><T><R><A><V><F><S><L><A><R><H><H><S><P><S><P><W><I><A><W><L><E><T><N><G><A><T><S><T><E><V><S><L><C><A><P... | Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.<BOP> | O43548 |
Q2YD98 | UVSSA_HUMAN | UV-stimulated scaffold protein A | Homo | <M><D><Q><K><L><S><K><L><V><E><E><L><T><T><S><G><E><P><R><L><N><P><E><K><M><K><E><L><K><K><I><C><K><S><S><E><E><Q><L><S><R><A><Y><R><L><L><I><A><Q><L><T><Q><E><H><A><E><I><R><L><S><A><F><Q><I><V><E><E><L><F><V><R><S><H><Q><F><R><M><L><V><V><S><N><F><Q><E><F><L><E><L><T><L><G><T><D><P><A><Q><P><L><P><P><P><R><E><A><A><Q... | Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complex... | Q2YD98 |
Q9BVV7 | TIM21_HUMAN | TIM21-like protein, mitochondrial | Homo | <M><I><C><T><F><L><R><A><V><Q><Y><T><E><K><L><H><R><S><S><A><K><R><L><L><L><P><Y><I><V><L><N><K><A><C><L><K><T><E><P><S><L><R><C><G><L><Q><Y><Q><K><K><T><L><R><P><R><C><I><L><G><V><T><Q><K><T><I><W><T><Q><G><P><S><P><R><K><A><K><E><D><G><S><K><Q><V><S><V><H><R><S><Q><R><G><G><T><A><V><P><T><S><Q><K><V><K><E><A><G><R><D... | Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex)... | Q9BVV7 |
Q9BTX3 | TM208_HUMAN | Transmembrane protein 208 | Homo | <M><A><P><K><G><K><V><G><T><R><G><K><K><Q><I><F><E><E><N><R><E><T><L><K><F><Y><L><R><I><I><L><G><A><N><A><I><Y><C><L><V><T><L><V><F><F><Y><S><S><A><S><F><W><A><W><L><A><L><G><F><S><L><A><V><Y><G><A><S><Y><H><S><M><S><S><M><A><R><A><A><F><S><E><D><G><A><L><M><D><G><G><M><D><L><N><M><E><Q><G><M><A><E><H><L><K><D><V><I><L... | May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.<BOP> | Q9BTX3 |
P04155 | TFF1_HUMAN | Protein pS2 | Homo | <M><A><T><M><E><N><K><V><I><C><A><L><V><L><V><S><M><L><A><L><G><T><L><A><E><A><Q><T><E><T><C><T><V><A><P><R><E><R><Q><N><C><G><F><P><G><V><T><P><S><Q><C><A><N><K><G><C><C><F><D><D><T><V><R><G><V><P><W><C><F><Y><P><N><T><I><D><V><P><P><E><E><E><C><E><F> | Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.<BOP> | P04155 |
Q6IF36 | O8G2P_HUMAN | Olfactory receptor TPCR120 | Homo | <M><V><F><L><S><S><V><E><T><D><Q><R><K><M><S><A><G><N><H><S><S><V><T><E><F><I><L><A><G><L><S><E><Q><P><E><L><Q><L><R><L><F><L><L><F><L><G><I><Y><V><V><T><V><V><G><N><L><S><M><I><T><L><I><G><L><S><S><H><L><H><T><P><M><Y><Y><F><L><S><G><L><S><F><I><D><L><C><H><S><T><I><I><T><P><K><M><L><V><N><F><V><T><E><K><N><I><I><S><Y... | Odorant receptor.<BOP> | Q6IF36 |
Q96AY2 | EME1_HUMAN | MMS4 homolog | Homo | <M><A><L><K><K><S><S><P><S><L><D><S><G><D><S><D><S><E><E><L><P><T><F><A><F><L><K><K><E><P><S><S><T><K><R><R><Q><P><E><R><E><E><K><I><V><V><V><D><I><S><D><C><E><A><S><C><P><P><A><P><E><L><F><S><P><P><V><P><E><I><A><E><T><V><T><Q><T><Q><P><V><R><L><L><S><S><E><S><E><D><E><E><E><F><I><P><L><A><Q><R><L><T><C><K><F><L><T><H... | Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed... | Q96AY2 |
Q9Y226 | S22AD_HUMAN | Organic cation transporter-like 3 | Homo | <M><A><Q><F><V><Q><V><L><A><E><I><G><D><F><G><R><F><Q><I><Q><L><L><I><L><L><C><V><L><N><F><L><S><P><F><Y><F><F><A><H><V><F><M><V><L><D><E><P><H><H><C><A><V><A><W><V><K><N><H><T><F><N><L><S><A><A><E><Q><L><V><L><S><V><P><L><D><T><A><G><H><P><E><P><C><L><M><F><R><P><P><P><A><N><A><S><L><Q><D><I><L><S><H><R><F><N><E><T><Q... | Anion antiporter that mediates the transport of urate, orotate and nicotinate in exchange for organic or inorganic anions . Translocates urate and orotate across the apical membrane of proximal tubule epithelial cells and involved in urate renal reabsorption . Possibly involved in orotate renal reabsorption and nicotin... | Q9Y226 |
Q96R09 | OR5B2_HUMAN | Olfactory receptor OR11-240 | Homo | <M><E><N><C><T><E><V><T><K><F><I><L><L><G><L><T><S><V><P><E><L><Q><I><P><L><F><I><L><F><T><F><I><Y><L><L><T><L><C><G><N><L><G><M><M><L><L><I><L><M><D><S><C><L><H><T><P><M><Y><F><F><L><S><N><L><S><L><V><D><F><G><Y><S><S><A><V><T><P><K><V><M><A><G><F><L><R><G><D><K><V><I><S><Y><N><A><C><A><V><Q><M><F><F><F><V><A><L><A><T... | Odorant receptor.<BOP> | Q96R09 |
O95158 | NXPH4_HUMAN | Neurexophilin-4 | Homo | <M><R><L><L><P><E><W><F><L><L><L><F><G><P><W><L><L><R><K><A><V><S><A><Q><I><P><E><S><G><R><P><Q><Y><L><G><L><R><P><A><A><A><G><A><G><A><P><G><Q><Q><L><P><E><P><R><S><S><D><G><L><G><V><G><R><A><W><S><W><A><W><P><T><N><H><T><G><A><L><A><R><A><G><A><A><G><A><L><P><A><Q><R><T><K><R><K><P><S><I><K><A><A><R><A><K><K><I><F><G... | May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors.<BOP> | O95158 |
Q08AE8 | SPIR1_HUMAN | Protein spire homolog 1 | Homo | <M><A><Q><A><A><G><P><A><G><G><G><E><P><R><T><E><A><V><G><G><E><G><P><R><E><P><G><A><A><G><G><A><A><G><G><S><R><D><A><L><S><L><E><E><I><L><R><L><Y><N><Q><P><I><N><E><E><Q><A><W><A><V><C><Y><Q><C><C><G><S><L><R><A><A><A><R><R><R><Q><P><R><H><R><V><R><S><A><A><Q><I><R><V><W><R><D><G><A><V><T><L><A><P><A><A><D><D><A><G><E... | Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament . Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport . Required for asymmetric spindle positioning and asymmetr... | Q08AE8 |
P0C1H6 | H2BFM_HUMAN | Histone H2B.s | Homo | <M><A><A><A><S><A><M><A><E><A><S><S><E><T><T><S><E><E><G><Q><S><I><Q><E><P><K><E><A><N><S><T><K><A><Q><K><Q><K><R><R><G><C><R><G><S><R><R><R><H><A><N><R><R><G><D><S><F><G><D><S><F><T><P><Y><F><P><R><V><L><K><Q><V><H><Q><G><L><S><L><S><Q><E><A><V><S><V><M><D><S><M><I><H><D><I><L><D><R><I><A><T><E><A><G><Q><L><A><H><Y><T... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | P0C1H6 |
Q99583 | MNT_HUMAN | Protein ROX | Homo | <M><S><I><E><T><L><L><E><A><A><R><F><L><E><W><Q><A><Q><Q><Q><Q><R><A><R><E><E><Q><E><R><L><R><L><E><Q><E><R><E><Q><E><Q><K><K><A><N><S><L><A><R><L><A><H><T><L><P><V><E><E><P><R><M><E><A><P><P><L><P><L><S><P><P><A><P><P><P><A><P><P><P><P><L><A><T><P><A><P><L><T><V><I><P><I><P><V><V><T><N><S><P><Q><P><L><P><P><P><P><P><L... | Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.<BOP> | Q99583 |
Q5SGD2 | PPM1L_HUMAN | Protein phosphatase 2C isoform epsilon | Homo | <M><I><E><D><T><M><T><L><L><S><L><L><G><R><I><M><R><Y><F><L><L><R><P><E><T><L><F><L><L><C><I><S><L><A><L><W><S><Y><F><F><H><T><D><E><V><K><T><I><V><K><S><S><R><D><A><V><K><M><V><K><G><K><V><A><E><I><M><Q><N><D><R><L><G><G><L><D><V><L><E><A><E><F><S><K><T><W><E><F><K><N><H><N><V><A><V><Y><S><I><Q><G><R><R><D><H><M><E><D... | Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.<BOP> | Q5SGD2 |
O14649 | KCNK3_HUMAN | Two pore potassium channel KT3.1 | Homo | <M><K><R><Q><N><V><R><T><L><A><L><I><V><C><T><F><T><Y><L><L><V><G><A><A><V><F><D><A><L><E><S><E><P><E><L><I><E><R><Q><R><L><E><L><R><Q><Q><E><L><R><A><R><Y><N><L><S><Q><G><G><Y><E><E><L><E><R><V><V><L><R><L><K><P><H><K><A><G><V><Q><W><R><F><A><G><S><F><Y><F><A><I><T><V><I><T><T><I><G><Y><G><H><A><A><P><S><T><D><G><G><K... | pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.<BOP> | O14649 |
P16150 | LEUK_HUMAN | CD43 cytoplasmic tail | Homo | <M><A><T><L><L><L><L><L><G><V><L><V><V><S><P><D><A><L><G><S><T><T><A><V><Q><T><P><T><S><G><E><P><L><V><S><T><S><E><P><L><S><S><K><M><Y><T><T><S><I><T><S><D><P><K><A><D><S><T><G><D><Q><T><S><A><L><P><P><S><T><S><I><N><E><G><S><P><L><W><T><S><I><G><A><S><T><G><S><P><L><P><E><P><T><T><Y><Q><E><V><S><I><K><M><S><S><V><P><Q... | Protects cells from apoptotic signals, promoting cell survival.<BOP> | P16150 |
Q16625 | OCLN_HUMAN | Occludin | Homo | <M><S><S><R><P><L><E><S><P><P><P><Y><R><P><D><E><F><K><P><N><H><Y><A><P><S><N><D><I><Y><G><G><E><M><H><V><R><P><M><L><S><Q><P><A><Y><S><F><Y><P><E><D><E><I><L><H><F><Y><K><W><T><S><P><P><G><V><I><R><I><L><S><M><L><I><I><V><M><C><I><A><I><F><A><C><V><A><S><T><L><A><W><D><R><G><Y><G><T><S><L><L><G><G><S><V><G><Y><P><Y><G... | (Microbial infection) Acts as a coreceptor for hepatitis C virus (HCV) in hepatocytes.<BOP> | Q16625 |
Q7RTU7 | SCX_HUMAN | Class A basic helix-loop-helix protein 48 | Homo | <M><S><F><A><T><L><R><P><A><P><P><G><R><Y><L><Y><P><E><V><S><P><L><S><E><D><E><D><R><G><S><D><S><S><G><S><D><E><K><P><C><R><V><H><A><A><R><C><G><L><Q><G><A><R><R><R><A><G><G><R><R><A><G><G><G><G><P><G><G><R><P><G><R><E><P><R><Q><R><H><T><A><N><A><R><E><R><D><R><T><N><S><V><N><T><A><F><T><A><L><R><T><L><I><P><T><E><P><A... | Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.<BOP> | Q7RTU7 |
Q8NGN7 | O10D4_HUMAN | Putative olfactory receptor 10D4 | Homo | <M><R><N><H><T><M><V><T><E><F><I><L><L><G><I><P><E><T><E><G><L><E><T><A><L><L><F><L><F><S><S><F><Y><L><C><T><L><L><G><N><V><L><I><L><T><A><I><I><S><S><T><R><L><H><T><P><M><Y><F><F><L><G><N><L><S><I><F><D><L><G><F><S><S><T><T><V><P><K><M><L><F><Y><L><S><G><N><S><H><A><I><S><Y><A><G><C><V><S><Q><L><F><F><Y><H><F><L><G><C... | Odorant receptor.<BOP> | Q8NGN7 |
Q9ULV4 | COR1C_HUMAN | hCRNN4 | Homo | <M><R><R><V><V><R><Q><S><K><F><R><H><V><F><G><Q><A><V><K><N><D><Q><C><Y><D><D><I><R><V><S><R><V><T><W><D><S><S><F><C><A><V><N><P><R><F><V><A><I><I><I><E><A><S><G><G><G><A><F><L><V><L><P><L><H><K><T><G><R><I><D><K><S><Y><P><T><V><C><G><H><T><G><P><V><L><D><I><D><W><C><P><H><N><D><Q><V><I><A><S><G><S><E><D><C><T><V><M><V... | Involved in myogenic differentiation.<BOP> | Q9ULV4 |
P46091 | CML2_HUMAN | G-protein coupled receptor 1 | Homo | <M><E><D><L><E><E><T><L><F><E><E><F><E><N><Y><S><Y><D><L><D><Y><Y><S><L><E><S><D><L><E><E><K><V><Q><L><G><V><V><H><W><V><S><L><V><L><Y><C><L><A><F><V><L><G><I><P><G><N><A><I><V><I><W><F><T><G><F><K><W><K><K><T><V><T><T><L><W><F><L><N><L><A><I><A><D><F><I><F><L><L><F><L><P><L><Y><I><S><Y><V><A><M><N><F><H><W><P><F><G><I... | (Microbial infection) Coreceptor for HIV-1.<BOP> | P46091 |
Q53S33 | BOLA3_HUMAN | BolA-like protein 3 | Homo | <M><A><A><W><S><P><A><A><A><A><P><L><L><R><G><I><R><G><L><P><L><H><H><R><M><F><A><T><Q><T><E><G><E><L><R><V><T><Q><I><L><K><E><K><F><P><R><A><T><A><I><K><V><T><D><I><S><G><G><C><G><A><M><Y><E><I><K><I><E><S><E><E><F><K><E><K><R><T><V><Q><Q><H><Q><M><V><N><Q><A><L><K><E><E><I><K><E><M><H><G><L><R><I><F><T><S><V><P><K><R... | Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins. Probably acts together with NFU1 .<BOP> | Q53S33 |
Q12933 | TRAF2_HUMAN | Tumor necrosis factor type 2 receptor-associated protein 3 | Homo | <M><A><A><A><S><V><T><P><P><G><S><L><E><L><L><Q><P><G><F><S><K><T><L><L><G><T><K><L><E><A><K><Y><L><C><S><A><C><R><N><V><L><R><R><P><F><Q><A><Q><C><G><H><R><Y><C><S><F><C><L><A><S><I><L><S><S><G><P><Q><N><C><A><A><C><V><H><E><G><I><Y><E><E><G><I><S><I><L><E><S><S><S><A><F><P><D><N><A><A><R><R><E><V><E><S><L><P><A><V><C... | Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. ... | Q12933 |
Q13509 | TBB3_HUMAN | Tubulin beta-III | Homo | <M><R><E><I><V><H><I><Q><A><G><Q><C><G><N><Q><I><G><A><K><F><W><E><V><I><S><D><E><H><G><I><D><P><S><G><N><Y><V><G><D><S><D><L><Q><L><E><R><I><S><V><Y><Y><N><E><A><S><S><H><K><Y><V><P><R><A><I><L><V><D><L><E><P><G><T><M><D><S><V><R><S><G><A><F><G><H><L><F><R><P><D><N><F><I><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers . Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms . Below the cap, tubulin dimers are in GD... | Q13509 |
Q96CK0 | ZN653_HUMAN | Zinc finger protein Zip67 | Homo | <M><A><E><R><A><L><E><P><E><A><E><A><E><A><E><A><G><A><G><G><E><A><A><A><E><E><G><A><A><G><R><K><A><R><G><R><P><R><L><T><E><S><D><R><A><R><R><R><L><E><S><R><K><K><Y><D><V><R><R><V><Y><L><G><E><A><H><G><P><W><V><D><L><R><R><R><S><G><W><S><D><A><K><L><A><A><Y><L><I><S><L><E><R><G><Q><R><S><G><R><H><G><K><P><W><E><Q><V><P... | Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity.<BOP> | Q96CK0 |
Q96SD1 | DCR1C_HUMAN | SNM1-like protein | Homo | <M><S><S><F><E><G><Q><M><A><E><Y><P><T><I><S><I><D><R><F><D><R><E><N><L><R><A><R><A><Y><F><L><S><H><C><H><K><D><H><M><K><G><L><R><A><P><T><L><K><R><R><L><E><C><S><L><K><V><Y><L><Y><C><S><P><V><T><K><E><L><L><L><T><S><P><K><Y><R><F><W><K><K><R><I><I><S><I><E><I><E><T><P><T><Q><I><S><L><V><D><E><A><S><G><E><K><E><E><I><V... | Nuclease involved in DNA non-homologous end joining (NHEJ); required for double-strand break repair and V(D)J recombination . Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene... | Q96SD1 |
P0CE72 | ONCO_HUMAN | Parvalbumin beta | Homo | <M><S><I><T><D><V><L><S><A><D><D><I><A><A><A><L><Q><E><C><R><D><P><D><T><F><E><P><Q><K><F><F><Q><T><S><G><L><S><K><M><S><A><N><Q><V><K><D><V><F><R><F><I><D><N><D><Q><S><G><Y><L><D><E><E><E><L><K><F><F><L><Q><K><F><E><S><G><A><R><E><L><T><E><S><E><T><K><S><L><M><A><A><A><D><N><D><G><D><G><K><I><G><A><E><E><F><Q><E><M><V... | Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions.<BOP> | P0CE72 |
P43353 | AL3B1_HUMAN | Aldehyde dehydrogenase 7 | Homo | <M><D><P><L><G><D><T><L><R><R><L><R><E><A><F><H><A><G><R><T><R><P><A><E><F><R><A><A><Q><L><Q><G><L><G><R><F><L><Q><E><N><K><Q><L><L><H><D><A><L><A><Q><D><L><H><K><S><A><F><E><S><E><V><S><E><V><A><I><S><Q><G><E><V><T><L><A><L><R><N><L><R><A><W><M><K><D><E><R><V><P><K><N><L><A><T><Q><L><D><S><A><F><I><R><K><E><P><F><G><L... | Oxidizes medium and long chain saturated and unsaturated aldehydes . Metabolizes also benzaldehyde . Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde . May not metabolize short chain aldehydes. Can use both NADP(+) and NAD(+) as electron acceptor . May have a protective role against the cytotoxicit... | P43353 |
P25800 | RBTN1_HUMAN | T-cell translocation protein 1 | Homo | <M><M><V><L><D><K><E><D><G><V><P><M><L><S><V><Q><P><K><G><K><Q><K><G><C><A><G><C><N><R><K><I><K><D><R><Y><L><L><K><A><L><D><K><Y><W><H><E><D><C><L><K><C><A><C><C><D><C><R><L><G><E><V><G><S><T><L><Y><T><K><A><N><L><I><L><C><R><R><D><Y><L><R><L><F><G><T><T><G><N><C><A><A><C><S><K><L><I><P><A><F><E><M><V><M><R><A><R><D><N... | May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.<BOP> | P25800 |
O60232 | ZNRD2_HUMAN | Zinc ribbon domain-containing protein 2 | Homo | <M><A><L><N><G><A><E><V><D><D><F><S><W><E><P><P><T><E><A><E><T><K><V><L><Q><A><R><R><E><R><Q><D><R><I><S><R><L><M><G><D><Y><L><L><R><G><Y><R><M><L><G><E><T><C><A><D><C><G><T><I><L><L><Q><D><K><Q><R><K><I><Y><C><V><A><C><Q><E><L><D><S><D><V><D><K><D><N><P><A><L><N><A><Q><A><A><L><S><Q><A><R><E><H><Q><L><A><S><A><S><E><L... | Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.<BOP> | O60232 |
P09693 | CD3G_HUMAN | T-cell receptor T3 gamma chain | Homo | <M><E><Q><G><K><G><L><A><V><L><I><L><A><I><I><L><L><Q><G><T><L><A><Q><S><I><K><G><N><H><L><V><K><V><Y><D><Y><Q><E><D><G><S><V><L><L><T><C><D><A><E><A><K><N><I><T><W><F><K><D><G><K><M><I><G><F><L><T><E><D><K><K><K><W><N><L><G><S><N><A><K><D><P><R><G><M><Y><Q><C><K><G><S><Q><N><K><S><K><P><L><Q><V><Y><Y><R><M><C><Q><N><C... | Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contai... | P09693 |
Q9HB31 | SEBOX_HUMAN | Skin-, embryo-, brain- and oocyte-specific homeobox | Homo | <M><P><S><P><V><D><A><S><S><A><D><G><G><S><G><L><G><S><H><R><R><K><R><T><T><F><S><K><G><Q><L><L><E><L><E><R><A><F><A><A><W><P><Y><P><N><I><S><T><H><E><H><L><A><W><V><T><C><L><P><E><A><K><V><Q><V><W><F><Q><K><R><W><A><K><I><I><K><N><R><K><S><G><I><L><S><P><G><S><E><C><P><Q><S><S><C><S><L><P><D><T><L><Q><Q><P><W><D><P><Q... | Probable transcription factor involved in the control of specification of mesoderm and endoderm.<BOP> | Q9HB31 |
Q9H0C8 | ILKAP_HUMAN | Integrin-linked kinase-associated serine/threonine phosphatase 2C | Homo | <M><D><L><F><G><D><L><P><E><P><E><R><S><P><R><P><A><A><G><K><E><A><Q><K><G><P><L><L><F><D><D><L><P><P><A><S><S><T><D><S><G><S><G><G><P><L><L><F><D><D><L><P><P><A><S><S><G><D><S><G><S><L><A><T><S><I><S><Q><M><V><K><T><E><G><K><G><A><K><R><K><T><S><E><E><E><K><N><G><S><E><E><L><V><E><K><K><V><C><K><A><S><S><V><I><F><G><L... | Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhi... | Q9H0C8 |
Q16773 | KAT1_HUMAN | Kynurenine--oxoglutarate transaminase I | Homo | <M><A><K><Q><L><Q><A><R><R><L><D><G><I><D><Y><N><P><W><V><E><F><V><K><L><A><S><E><H><D><V><V><N><L><G><Q><G><F><P><D><F><P><P><P><D><F><A><V><E><A><F><Q><H><A><V><S><G><D><F><M><L><N><Q><Y><T><K><T><F><G><Y><P><P><L><T><K><I><L><A><S><F><F><G><E><L><L><G><Q><E><I><D><P><L><R><N><V><L><V><T><V><G><G><Y><G><A><L><F><T><A... | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others . Also metabolizes the cysteine conjugates... | Q16773 |
O43175 | SERA_HUMAN | Malate dehydrogenase | Homo | <M><A><F><A><N><L><R><K><V><L><I><S><D><S><L><D><P><C><C><R><K><I><L><Q><D><G><G><L><Q><V><V><E><K><Q><N><L><S><K><E><E><L><I><A><E><L><Q><D><C><E><G><L><I><V><R><S><A><T><K><V><T><A><D><V><I><N><A><A><E><K><L><Q><V><V><G><R><A><G><T><G><V><D><N><V><D><L><E><A><A><T><R><K><G><I><L><V><M><N><T><P><N><G><N><S><L><S><A><A... | Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.<BOP> | O43175 |
Q9Y4J8 | DTNA_HUMAN | Dystrophin-related protein 3 | Homo | <M><I><E><D><S><G><K><R><G><N><T><M><A><E><R><R><Q><L><F><A><E><M><R><A><Q><D><L><D><R><I><R><L><S><T><Y><R><T><A><C><K><L><R><F><V><Q><K><K><C><N><L><H><L><V><D><I><W><N><V><I><E><A><L><R><E><N><A><L><N><N><L><D><P><N><T><E><L><N><V><S><R><L><E><A><V><L><S><T><I><F><Y><Q><L><N><K><R><M><P><T><T><H><Q><I><H><V><E><Q><S... | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.<BOP> | Q9Y4J8 |
Q8NGS1 | OR1J4_HUMAN | Olfactory receptor OR9-21 | Homo | <M><K><R><E><N><Q><S><S><V><S><E><F><L><L><L><D><L><P><I><W><P><E><Q><Q><A><V><F><F><T><L><F><L><G><M><Y><L><I><T><V><L><G><N><L><L><I><I><L><L><I><R><L><D><S><H><L><H><T><P><M><F><F><F><L><S><H><L><A><L><T><D><I><S><L><S><S><V><T><V><P><K><M><L><L><S><M><Q><T><Q><D><Q><S><I><L><Y><A><G><C><V><T><Q><M><Y><F><F><I><F><F... | Odorant receptor.<BOP> | Q8NGS1 |
Q8NH67 | O52I2_HUMAN | Olfactory receptor OR11-12 | Homo | <M><C><Q><Q><I><L><R><D><C><I><L><L><I><H><H><L><C><I><N><R><K><K><V><S><L><V><M><L><G><P><A><Y><N><H><T><M><E><T><P><A><S><F><L><L><V><G><I><P><G><L><Q><S><S><H><L><W><L><A><I><S><L><S><A><M><Y><I><I><A><L><L><G><N><T><I><I><V><T><A><I><W><M><D><S><T><R><H><E><P><M><Y><C><F><L><C><V><L><A><A><V><D><I><V><M><A><S><S><V... | Odorant receptor.<BOP> | Q8NH67 |
P54619 | AAKG1_HUMAN | 5'-AMP-activated protein kinase subunit gamma-1 | Homo | <M><E><T><V><I><S><S><D><S><S><P><A><V><E><N><E><H><P><Q><E><T><P><E><S><N><N><S><V><Y><T><S><F><M><K><S><H><R><C><Y><D><L><I><P><T><S><S><K><L><V><V><F><D><T><S><L><Q><V><K><K><A><F><F><A><L><V><T><N><G><V><R><A><A><P><L><W><D><S><K><K><Q><S><F><V><G><M><L><T><I><T><D><F><I><N><I><L><H><R><Y><Y><K><S><A><L><V><Q><I><Y... | AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carboh... | P54619 |
P16671 | CD36_HUMAN | Thrombospondin receptor | Homo | <M><G><C><D><R><N><C><G><L><I><A><G><A><V><I><G><A><V><L><A><V><F><G><G><I><L><M><P><V><G><D><L><L><I><Q><K><T><I><K><K><Q><V><V><L><E><E><G><T><I><A><F><K><N><W><V><K><T><G><T><E><V><Y><R><Q><F><W><I><F><D><V><Q><N><P><Q><E><V><M><M><N><S><S><N><I><Q><V><K><Q><R><G><P><Y><T><Y><R><V><R><F><L><A><K><E><N><V><T><Q><D><A... | (Microbial infection) Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and the internalization of particles independently of TLR signaling.<BOP> | P16671 |
P07992 | ERCC1_HUMAN | DNA excision repair protein ERCC-1 | Homo | <M><D><P><G><K><D><K><E><G><V><P><Q><P><S><G><P><P><A><R><K><K><F><V><I><P><L><D><E><D><E><V><P><P><G><V><A><K><P><L><F><R><S><T><Q><S><L><P><T><V><D><T><S><A><Q><A><A><P><Q><T><Y><A><E><Y><A><I><S><Q><P><L><E><G><A><G><A><T><C><P><T><G><S><E><P><L><A><G><E><T><P><N><Q><A><L><K><P><G><A><K><S><N><S><I><I><V><S><P><R><Q... | Not functional in the nucleotide excision repair pathway.<BOP> | P07992 |
P35813 | PPM1A_HUMAN | Protein phosphatase IA | Homo | <M><G><A><F><L><D><K><P><K><M><E><K><H><N><A><Q><G><Q><G><N><G><L><R><Y><G><L><S><S><M><Q><G><W><R><V><E><M><E><D><A><H><T><A><V><I><G><L><P><S><G><L><E><S><W><S><F><F><A><V><Y><D><G><H><A><G><S><Q><V><A><K><Y><C><C><E><H><L><L><D><H><I><T><N><N><Q><D><F><K><G><S><A><G><A><P><S><V><E><N><V><K><N><G><I><R><T><G><F><L><E... | Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination o... | P35813 |
P51787 | KCNQ1_HUMAN | Voltage-gated potassium channel subunit Kv7.1 | Homo | <M><A><A><A><S><S><P><P><R><A><E><R><K><R><W><G><W><G><R><L><P><G><A><R><R><G><S><A><G><L><A><K><K><C><P><F><S><L><E><L><A><E><G><G><P><A><G><G><A><L><Y><A><P><I><A><P><G><A><P><G><P><A><P><P><A><S><P><A><A><P><A><A><P><P><V><A><S><D><L><G><P><R><P><P><V><S><L><D><P><R><V><S><I><Y><S><T><R><R><P><V><L><A><R><T><H><V><Q... | Non-functional alone but modulatory when coexpressed with the full-length isoform 1.<BOP> | P51787 |
O95150 | TNF15_HUMAN | Tumor necrosis factor ligand superfamily member 15, secreted form | Homo | <M><A><E><D><L><G><L><S><F><G><E><T><A><S><V><E><M><L><P><E><H><G><S><C><R><P><K><A><R><S><S><S><A><R><W><A><L><T><C><C><L><V><L><L><P><F><L><A><G><L><T><T><Y><L><L><V><S><Q><L><R><A><Q><G><E><A><C><V><Q><F><Q><A><L><K><G><Q><E><F><A><P><S><H><Q><Q><V><Y><A><P><L><R><A><D><G><D><K><P><R><A><H><L><T><V><V><R><Q><T><P><T... | Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.<BOP> | O95150 |
Q86YB8 | ERO1B_HUMAN | Oxidoreductin-1-L-beta | Homo | <M><S><Q><G><V><R><R><A><G><A><G><Q><G><V><A><A><A><V><Q><L><L><V><T><L><S><F><L><R><S><V><V><E><A><Q><V><T><G><V><L><D><D><C><L><C><D><I><D><S><I><D><N><F><N><T><Y><K><I><F><P><K><I><K><K><L><Q><E><R><D><Y><F><R><Y><Y><K><V><N><L><K><R><P><C><P><F><W><A><E><D><G><H><C><S><I><K><D><C><H><V><E><P><C><P><E><S><K><I><P><V... | Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but a... | Q86YB8 |
Q9GZU8 | PIP30_HUMAN | PA28G-interacting protein | Homo | <M><D><G><G><D><D><G><N><L><I><I><K><K><R><F><V><S><E><A><E><L><D><E><R><R><K><R><R><Q><E><E><W><E><K><V><R><K><P><E><D><P><E><E><C><P><E><E><V><Y><D><P><R><S><L><Y><E><R><L><Q><E><Q><K><D><R><K><Q><Q><E><Y><E><E><Q><F><K><F><K><N><M><V><R><G><L><D><E><D><E><T><N><F><L><D><E><V><S><R><Q><Q><E><L><I><E><K><Q><R><R><E><E... | Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME... | Q9GZU8 |
Q9UHY7 | ENOPH_HUMAN | MASA homolog | Homo | <M><V><V><L><S><V><P><A><E><V><T><V><I><L><L><D><I><E><G><T><T><T><P><I><A><F><V><K><D><I><L><F><P><Y><I><E><E><N><V><K><E><Y><L><Q><T><H><W><E><E><E><E><C><Q><Q><D><V><S><L><L><R><K><Q><A><E><E><D><A><H><L><D><G><A><V><P><I><P><A><A><S><G><N><G><V><D><D><L><Q><Q><M><I><Q><A><V><V><D><N><V><C><W><Q><M><S><L><D><R><K><T... | Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).<BOP> | Q9UHY7 |
Q9UII2 | ATIF1_HUMAN | Inhibitor of F(1)F(o)-ATPase | Homo | <M><A><V><T><A><L><A><A><R><T><W><L><G><V><W><G><V><R><T><M><Q><A><R><G><F><G><S><D><Q><S><E><N><V><D><R><G><A><G><S><I><R><E><A><G><G><A><F><G><K><R><E><Q><A><E><E><E><R><Y><F><R><A><Q><S><R><E><Q><L><A><A><L><K><K><H><H><E><E><E><I><V><H><H><K><K><E><I><E><R><L><Q><K><E><I><E><R><H><K><Q><K><I><K><M><L><K><H><D><D> | Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts... | Q9UII2 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.