accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q5T7P2 | LCE1A_HUMAN | Late envelope protein 1 | Homo | <M><S><C><Q><Q><S><Q><Q><Q><C><Q><P><P><P><K><C><T><P><K><C><P><P><K><C><P><T><P><K><C><P><P><K><C><P><P><K><C><P><P><V><S><S><C><C><S><V><S><S><G><G><C><C><G><S><S><S><G><G><G><C><S><S><G><G><G><G><C><C><L><S><H><H><R><R><H><R><S><H><R><H><R><L><Q><S><S><G><C><C><S><Q><P><S><G><G><S><S><C><C><G><G><D><S><G><Q><H><S><G... | Precursors of the cornified envelope of the stratum corneum.<BOP> | Q5T7P2 |
O75387 | LAT3_HUMAN | Solute carrier family 43 member 1 | Homo | <M><A><P><T><L><Q><Q><A><Y><R><R><R><W><W><M><A><C><T><A><V><L><E><N><L><F><F><S><A><V><L><L><G><W><G><S><L><L><I><I><L><K><N><E><G><F><Y><S><S><T><C><P><A><E><S><S><T><N><T><T><Q><D><E><Q><R><R><W><P><G><C><D><Q><Q><D><E><M><L><N><L><G><F><T><I><G><S><F><V><L><S><A><T><T><L><P><L><G><I><L><M><D><R><F><G><P><R><P><V><R... | Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive pr... | O75387 |
Q9H344 | O51I2_HUMAN | Olfactory receptor OR11-38 | Homo | <M><G><L><F><N><V><T><H><P><A><F><F><L><L><T><G><I><P><G><L><E><S><S><H><S><W><L><S><G><P><L><C><V><M><Y><A><V><A><L><G><G><N><T><V><I><L><Q><A><V><R><V><E><P><S><L><H><E><P><M><Y><Y><F><L><S><M><L><S><F><S><D><V><A><I><S><M><A><T><L><P><T><V><L><R><T><F><C><L><N><A><R><N><I><T><F><D><A><C><L><I><Q><M><F><L><I><H><F><F... | Odorant receptor.<BOP> | Q9H344 |
P09455 | RET1_HUMAN | Cellular retinol-binding protein I | Homo | <M><P><V><D><F><T><G><Y><W><K><M><L><V><N><E><N><F><E><E><Y><L><R><A><L><D><V><N><V><A><L><R><K><I><A><N><L><L><K><P><D><K><E><I><V><Q><D><G><D><H><M><I><I><R><T><L><S><T><F><R><N><Y><I><M><D><F><Q><V><G><K><E><F><E><E><D><L><T><G><I><D><D><R><K><C><M><T><T><V><S><W><D><G><D><K><L><Q><C><V><Q><K><G><E><K><E><G><R><G><W... | Cytoplasmic retinol-binding protein . Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis .<BOP> | P09455 |
Q5T5A8 | LCE3C_HUMAN | Small proline-rich-like epidermal differentiation complex protein 3A | Homo | <M><S><C><Q><Q><N><Q><Q><Q><C><Q><P><P><P><S><C><P><S><P><K><C><P><P><K><S><P><A><Q><C><L><P><P><P><S><S><D><C><A><L><S><S><G><G><C><G><P><S><S><E><S><G><C><C><L><S><H><H><R><H><F><R><S><H><Q><C><R><R><Q><R><S><N><S><C><D><R><G><S><G><Q><Q><G><G><G><S><C><R><G><H><G><S><G><G><C><C> | A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barr... | Q5T5A8 |
Q9C056 | NKX62_HUMAN | Homeobox protein NK-6 homolog B | Homo | <M><D><T><N><R><P><G><A><F><V><L><S><S><A><P><L><A><A><L><H><N><M><A><E><M><K><T><S><L><F><P><Y><A><L><Q><G><P><A><G><F><K><A><P><A><L><G><G><L><G><A><Q><L><P><L><G><T><P><H><G><I><S><D><I><L><G><R><P><V><G><A><A><G><G><G><L><L><G><G><L><P><R><L><N><G><L><A><S><S><A><G><V><Y><F><G><P><A><A><A><V><A><R><G><Y><P><K><P><L... | Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.<BOP> | Q9C056 |
A0A0C4DH27 | TRGV8_HUMAN | T cell receptor gamma variable 8 | Homo | <M><L><L><A><L><A><L><L><L><A><F><L><P><P><A><S><Q><K><S><S><N><L><E><G><R><T><K><S><V><T><R><P><T><G><S><S><A><V><I><T><C><D><L><P><V><E><N><A><V><Y><T><H><W><Y><L><H><Q><E><G><K><A><P><Q><R><L><L><Y><Y><D><S><Y><N><S><R><V><V><L><E><S><G><I><S><R><E><K><Y><H><T><Y><A><S><T><G><K><S><L><K><F><I><L><E><N><L><I><E><R><D... | V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition . Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids present... | A0A0C4DH27 |
P16619 | CL3L1_HUMAN | LD78-beta(5-70) | Homo | <M><Q><V><S><T><A><A><L><A><V><L><L><C><T><M><A><L><C><N><Q><V><L><S><A><P><L><A><A><D><T><P><T><A><C><C><F><S><Y><T><S><R><Q><I><P><Q><N><F><I><A><D><Y><F><E><T><S><S><Q><C><S><K><P><S><V><I><F><L><T><K><R><G><R><Q><V><C><A><D><P><S><E><E><W><V><Q><K><Y><V><S><D><L><E><L><S><A> | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.<BOP> | P16619 |
Q8TC26 | TM163_HUMAN | Transmembrane protein 163 | Homo | <M><E><P><A><A><G><I><Q><R><R><S><S><Q><G><P><T><V><P><P><P><P><R><G><H><A><P><P><A><A><A><P><G><P><A><P><L><S><S><P><V><R><E><P><P><Q><L><E><E><E><R><Q><V><R><I><S><E><S><G><Q><F><S><D><G><L><E><D><R><G><L><L><E><S><S><T><R><L><K><P><H><E><A><Q><N><Y><R><K><K><A><L><W><V><S><W><F><S><I><I><V><T><L><A><L><A><V><A><A><F... | May bind zinc and other divalent cations and recruit them to vesicular organelles.<BOP> | Q8TC26 |
Q00266 | METK1_HUMAN | Methionine adenosyltransferase I/III | Homo | <M><N><G><P><V><D><G><L><C><D><H><S><L><S><E><G><V><F><M><F><T><S><E><S><V><G><E><G><H><P><D><K><I><C><D><Q><I><S><D><A><V><L><D><A><H><L><K><Q><D><P><N><A><K><V><A><C><E><T><V><C><K><T><G><M><V><L><L><C><G><E><I><T><S><M><A><M><V><D><Y><Q><R><V><V><R><D><T><I><K><H><I><G><Y><D><D><S><A><K><G><F><D><F><K><T><C><N><V><L... | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.<BOP> | Q00266 |
P32302 | CXCR5_HUMAN | Monocyte-derived receptor 15 | Homo | <M><N><Y><P><L><T><L><E><M><D><L><E><N><L><E><D><L><F><W><E><L><D><R><L><D><N><Y><N><D><T><S><L><V><E><N><H><L><C><P><A><T><E><G><P><L><M><A><S><F><K><A><V><F><V><P><V><A><Y><S><L><I><F><L><L><G><V><I><G><N><V><L><V><L><V><I><L><E><R><H><R><Q><T><R><S><S><T><E><T><F><L><F><H><L><A><V><A><D><L><L><L><V><F><I><L><P><F><A... | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.<BOP> | P32302 |
O75355 | ENTP3_HUMAN | HB6 | Homo | <M><F><T><V><L><T><R><Q><P><C><E><Q><A><G><L><K><A><L><Y><R><T><P><T><I><I><A><L><V><V><L><L><V><S><I><V><V><L><V><S><I><T><V><I><Q><I><H><K><Q><E><V><L><P><P><G><L><K><Y><G><I><V><L><D><A><G><S><S><R><T><T><V><Y><V><Y><Q><W><P><A><E><K><E><N><N><T><G><V><V><S><Q><T><F><K><C><S><V><K><G><S><G><I><S><S><Y><G><N><N><P><Q... | Has a threefold preference for the hydrolysis of ATP over ADP.<BOP> | O75355 |
Q7RTS9 | DYM_HUMAN | Dyggve-Melchior-Clausen syndrome protein | Homo | <M><G><S><N><S><S><R><I><G><D><L><P><K><N><E><Y><L><K><K><L><S><G><T><E><S><I><S><E><N><D><P><F><W><N><Q><L><L><S><F><S><F><P><A><P><T><S><S><S><E><L><K><L><L><E><E><A><T><I><S><V><C><R><S><L><V><E><N><N><P><R><T><G><N><L><G><A><L><I><K><V><F><L><S><R><T><K><E><L><K><L><S><A><E><C><Q><N><H><I><F><I><W><Q><T><H><N><A><L... | Necessary for correct organization of Golgi apparatus. Involved in bone development.<BOP> | Q7RTS9 |
Q9NRH1 | YAE1_HUMAN | Yae1 domain-containing protein 1 | Homo | <M><S><W><V><Q><A><A><S><L><I><Q><G><P><G><D><K><G><D><V><F><D><E><E><A><D><E><S><L><L><A><Q><R><E><W><Q><S><N><M><Q><R><R><V><K><E><G><Y><R><D><G><I><D><A><G><K><A><V><T><L><Q><Q><G><F><N><Q><G><Y><K><K><G><A><E><V><I><L><N><Y><G><R><L><R><G><T><L><S><A><L><L><S><W><C><H><L><H><N><N><N><S><T><L><I><N><K><I><N><N><L><L... | The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery . May be required for biogenesis of the large ribosomal subunit and initiation of translation .<BOP> | Q9NRH1 |
Q96S16 | JMJD8_HUMAN | Jumonji domain-containing protein 8 | Homo | <M><A><P><A><S><R><L><L><A><L><W><A><L><A><A><V><A><L><P><G><S><G><A><E><G><D><G><G><W><R><P><G><G><P><G><A><V><A><E><E><E><R><C><T><V><E><R><R><A><D><L><T><Y><A><E><F><V><Q><Q><Y><A><F><V><R><P><V><I><L><Q><G><L><T><D><N><S><R><F><R><A><L><C><S><R><D><R><L><L><A><S><F><G><D><R><V><V><R><L><S><T><A><N><T><Y><S><Y><H><K... | Functions as a positive regulator of TNF-induced NF-kappa-B signaling . Regulates angiogenesis and cellular metabolism through interaction with PKM .<BOP> | Q96S16 |
Q9NVH1 | DJC11_HUMAN | DnaJ homolog subfamily C member 11 | Homo | <M><A><T><A><L><S><E><E><E><L><D><N><E><D><Y><Y><S><L><L><N><V><R><R><E><A><S><S><E><E><L><K><A><A><Y><R><R><L><C><M><L><Y><H><P><D><K><H><R><D><P><E><L><K><S><Q><A><E><R><L><F><N><L><V><H><Q><A><Y><E><V><L><S><D><P><Q><T><R><A><I><Y><D><I><Y><G><K><R><G><L><E><M><E><G><W><E><V><V><E><R><R><R><T><P><A><E><I><R><E><E><F... | Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex.<BOP> | Q9NVH1 |
P13473 | LAMP2_HUMAN | LGP-96 | Homo | <M><V><C><F><R><L><F><P><V><P><G><S><G><L><V><L><V><C><L><V><L><G><A><V><R><S><Y><A><L><E><L><N><L><T><D><S><E><N><A><T><C><L><Y><A><K><W><Q><M><N><F><T><V><R><Y><E><T><T><N><K><T><Y><K><T><V><T><I><S><D><H><G><T><V><T><Y><N><G><S><I><C><G><D><D><Q><N><G><P><K><I><A><V><Q><F><G><P><G><F><S><W><I><A><N><F><T><K><A><A><S... | (Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F.<BOP> | P13473 |
B4DX44 | ZN736_HUMAN | Zinc finger protein 736 | Homo | <M><G><V><L><T><F><R><D><V><A><V><E><F><S><P><E><E><W><E><C><L><D><S><A><Q><Q><R><L><Y><R><D><V><M><L><E><N><Y><G><N><L><V><S><L><G><L><A><I><F><K><P><D><L><M><T><C><L><E><Q><R><K><E><P><W><K><V><K><R><Q><E><A><V><A><K><H><P><A><G><S><F><H><F><T><A><E><I><L><P><D><H><D><I><K><D><S><F><Q><K><V><I><L><R><K><Y><G><S><C><D... | May be involved in transcriptional regulation.<BOP> | B4DX44 |
Q9UJK0 | TSR3_HUMAN | 20S S rRNA accumulation protein 3 homolog | Homo | <M><G><R><R><R><A><A><R><G><P><G><A><E><G><G><R><P><R><H><L><P><T><R><S><L><E><A><F><A><E><E><V><G><A><A><L><Q><A><S><V><E><P><G><A><A><D><G><E><G><G><P><G><P><A><A><L><P><C><T><L><A><M><W><E><L><G><H><C><D><P><R><R><C><T><G><R><K><L><A><R><L><G><L><V><R><C><L><R><L><G><H><R><F><G><G><L><V><L><S><P><V><G><K><Q><Y><A><S... | Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA (Probable). It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA (Probable)... | Q9UJK0 |
P17031 | ZNF26_HUMAN | Zinc finger protein KOX20 | Homo | <M><A><T><S><F><R><T><A><S><C><W><G><L><L><S><F><K><D><I><S><M><E><F><T><W><D><E><W><Q><L><L><D><S><T><Q><K><Y><L><Y><R><D><V><I><L><E><N><Y><H><N><L><I><S><V><G><Y><H><G><T><K><P><D><L><I><F><K><L><E><Q><G><E><D><P><W><I><I><N><A><K><I><S><R><Q><S><C><P><D><G><W><E><E><W><Y><Q><N><N><Q><D><E><L><E><S><I><E><R><S><Y><A... | May be involved in transcriptional regulation.<BOP> | P17031 |
Q8TAM1 | BBS10_HUMAN | Bardet-Biedl syndrome 10 protein | Homo | <M><L><S><S><M><A><A><A><G><S><V><K><A><A><L><Q><V><A><E><V><L><E><A><I><V><S><C><C><V><G><P><E><G><R><Q><V><L><C><T><K><P><T><G><E><V><L><L><S><R><N><G><G><R><L><L><E><A><L><H><L><E><H><P><I><A><R><M><I><V><D><C><V><S><S><H><L><K><K><T><G><D><G><A><K><T><F><I><I><F><L><C><H><L><L><R><G><L><H><A><I><T><D><R><E><K><D><P... | Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis . Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia . Involved in adipogenic differentiation .<BOP> | Q8TAM1 |
Q8NDH3 | PEPL1_HUMAN | Aminopeptidase-like 1 | Homo | <M><A><N><V><G><L><Q><F><Q><A><S><A><G><D><S><D><P><Q><S><R><P><L><L><L><L><G><Q><L><H><H><L><H><R><V><P><W><S><H><V><R><G><K><L><Q><P><R><V><T><E><E><L><W><Q><A><A><L><S><T><L><N><P><N><P><T><D><S><C><P><L><Y><L><N><Y><A><T><V><A><A><L><P><C><R><V><S><R><H><N><S><P><S><A><A><H><F><I><T><R><L><V><R><T><C><L><P><P><G><A... | Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.<BOP> | Q8NDH3 |
Q15382 | RHEB_HUMAN | Ras homolog enriched in brain | Homo | <M><P><Q><S><K><S><R><K><I><A><I><L><G><Y><R><S><V><G><K><S><S><L><T><I><Q><F><V><E><G><Q><F><V><D><S><Y><D><P><T><I><E><N><T><F><T><K><L><I><T><V><N><G><Q><E><Y><H><L><Q><L><V><D><T><A><G><Q><D><E><Y><S><I><F><P><Q><T><Y><S><I><D><I><N><G><Y><I><L><V><Y><S><V><T><S><I><K><S><F><E><V><I><K><V><I><H><G><K><L><L><D><M><V... | Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.<BOP> | Q15382 |
Q9Y4P1 | ATG4B_HUMAN | Autophagy-related protein 4 homolog B | Homo | <M><D><A><A><T><L><T><Y><D><T><L><R><F><A><E><F><E><D><F><P><E><T><S><E><P><V><W><I><L><G><R><K><Y><S><I><F><T><E><K><D><E><I><L><S><D><V><A><S><R><L><W><F><T><Y><R><K><N><F><P><A><I><G><G><T><G><P><T><S><D><T><G><W><G><C><M><L><R><C><G><Q><M><I><F><A><Q><A><L><V><C><R><H><L><G><R><D><W><R><W><T><Q><R><K><R><Q><P><D><S... | Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins . Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy . The protease activity is required for proteolytic activation of ATG8 family prote... | Q9Y4P1 |
P52292 | IMA1_HUMAN | SRP1-alpha | Homo | <M><S><T><N><E><N><A><N><T><P><A><A><R><L><H><R><F><K><N><K><G><K><D><S><T><E><M><R><R><R><R><I><E><V><N><V><E><L><R><K><A><K><K><D><D><Q><M><L><K><R><R><N><V><S><S><F><P><D><D><A><T><S><P><L><Q><E><N><R><N><N><Q><G><T><V><N><W><S><V><D><D><I><V><K><G><I><N><S><S><N><V><E><N><Q><L><Q><A><T><Q><A><A><R><K><L><L><S><R><E... | Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repe... | P52292 |
Q15102 | PA1B3_HUMAN | PAF-AH subunit gamma | Homo | <M><S><G><E><E><N><P><A><S><K><P><T><P><V><Q><D><V><Q><G><D><G><R><W><M><S><L><H><H><R><F><V><A><D><S><K><D><K><E><P><E><V><V><F><I><G><D><S><L><V><Q><L><M><H><Q><C><E><I><W><R><E><L><F><S><P><L><H><A><L><N><F><G><I><G><G><D><G><T><Q><H><V><L><W><R><L><E><N><G><E><L><E><H><I><R><P><K><I><V><V><V><W><V><G><T><N><N><H><G... | Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF. The activity and substrate specificity of PAF-AH (I) are af... | Q15102 |
Q13156 | RFA4_HUMAN | Replication factor A protein 4 | Homo | <M><S><K><S><G><F><G><S><Y><G><S><I><S><A><A><D><G><A><S><G><G><S><D><Q><L><C><E><R><D><A><T><P><A><I><K><T><Q><R><P><K><V><R><I><Q><D><V><V><P><C><N><V><N><Q><L><L><S><S><T><V><F><D><P><V><F><K><V><R><G><I><I><V><S><Q><V><S><I><V><G><V><I><R><G><A><E><K><A><S><N><H><I><C><Y><K><I><D><D><M><T><A><K><P><I><E><A><R><Q><W... | As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by... | Q13156 |
Q9NZK5 | ADA2_HUMAN | Cat eye syndrome critical region protein 1 | Homo | <M><L><V><D><G><P><S><E><R><P><A><L><C><F><L><L><L><A><V><A><M><S><F><F><G><S><A><L><S><I><D><E><T><R><A><H><L><L><L><K><E><K><M><M><R><L><G><G><R><L><V><L><N><T><K><E><E><L><A><N><E><R><L><M><T><L><K><I><A><E><M><K><E><A><M><R><T><L><I><F><P><P><S><M><H><F><F><Q><A><K><H><L><I><E><R><S><Q><V><F><N><I><L><R><M><M><P><K... | Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation ... | Q9NZK5 |
Q13772 | NCOA4_HUMAN | Ret-activating protein ELE1 | Homo | <M><N><T><F><Q><D><Q><S><G><S><S><S><N><R><E><P><L><L><R><C><S><D><A><R><R><D><L><E><L><A><I><G><G><V><L><R><A><E><Q><Q><I><K><D><N><L><R><E><V><K><A><Q><I><H><S><C><I><S><R><H><L><E><C><L><R><S><R><E><V><W><L><Y><E><Q><V><D><L><I><Y><Q><L><K><E><E><T><L><Q><Q><Q><A><Q><Q><L><Y><S><L><L><G><Q><F><N><C><L><T><H><Q><L><E... | Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.<BOP> | Q13772 |
O75380 | NDUS6_HUMAN | NADH-ubiquinone oxidoreductase 13 kDa-A subunit | Homo | <M><A><A><A><M><T><F><C><R><L><L><N><R><C><G><E><A><A><R><S><L><P><L><G><A><R><C><F><G><V><R><V><S><P><T><G><E><K><V><T><H><T><G><Q><V><Y><D><D><K><D><Y><R><R><I><R><F><V><G><R><Q><K><E><V><N><E><N><F><A><I><D><L><I><A><E><Q><P><V><S><E><V><E><T><R><V><I><A><C><D><G><G><G><G><A><L><G><H><P><K><V><Y><I><N><L><D><K><E><T... | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP> | O75380 |
P22303 | ACES_HUMAN | Acetylcholinesterase | Homo | <M><R><P><P><Q><C><L><L><H><T><P><S><L><A><S><P><L><L><L><L><L><L><W><L><L><G><G><G><V><G><A><E><G><R><E><D><A><E><L><L><V><T><V><R><G><G><R><L><R><G><I><R><L><K><T><P><G><G><P><V><S><A><F><L><G><I><P><F><A><E><P><P><M><G><P><R><R><F><L><P><P><E><P><K><Q><P><W><S><G><V><V><D><A><T><T><F><Q><S><V><C><Y><Q><Y><V><D><T><L... | Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.<BOP> | P22303 |
Q13596 | SNX1_HUMAN | Sorting nexin-1 | Homo | <M><A><S><G><G><G><G><C><S><A><S><E><R><L><P><P><P><F><P><G><L><E><P><E><S><E><G><A><A><G><G><S><E><P><E><A><G><D><S><D><T><E><G><E><D><I><F><T><G><A><A><V><V><S><K><H><Q><S><P><K><I><T><T><S><L><L><P><I><N><N><G><S><K><E><N><G><I><H><E><E><Q><D><Q><E><P><Q><D><L><F><A><D><A><T><V><E><L><S><L><D><S><T><Q><N><N><Q><K><K... | Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) . Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde ... | Q13596 |
P13765 | DOB_HUMAN | MHC class II antigen DOB | Homo | <M><G><S><G><W><V><P><W><V><V><A><L><L><V><N><L><T><R><L><D><S><S><M><T><Q><G><T><D><S><P><E><D><F><V><I><Q><A><K><A><D><C><Y><F><T><N><G><T><E><K><V><Q><F><V><V><R><F><I><F><N><L><E><E><Y><V><R><F><D><S><D><V><G><M><F><V><A><L><T><K><L><G><Q><P><D><A><E><Q><W><N><S><R><L><D><L><L><E><R><S><R><Q><A><V><D><G><V><C><R><H... | Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.<BOP> | P13765 |
Q3LI72 | KR195_HUMAN | Keratin-associated protein 19-5 | Homo | <M><N><Y><Y><G><N><Y><Y><G><G><L><G><Y><G><Y><G><G><F><D><D><L><G><Y><G><Y><G><C><G><C><G><S><F><R><R><L><G><Y><G><G><G><Y><G><G><Y><G><Y><G><S><G><F><G><G><Y><G><Y><R><S><C><R><P><S><C><Y><G><G><Y><G><F><S><G><F><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q3LI72 |
Q6PHR2 | ULK3_HUMAN | Unc-51-like kinase 3 | Homo | <M><A><G><P><G><W><G><P><P><R><L><D><G><F><I><L><T><E><R><L><G><S><G><T><Y><A><T><V><Y><K><A><Y><A><K><K><D><T><R><E><V><V><A><I><K><C><V><A><K><K><S><L><N><K><A><S><V><E><N><L><L><T><E><I><E><I><L><K><G><I><R><H><P><H><I><V><Q><L><K><D><F><Q><W><D><S><D><N><I><Y><L><I><M><E><F><C><A><G><G><D><L><S><R><F><I><H><T><R><R... | Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GL... | Q6PHR2 |
Q6UXZ0 | TMIG1_HUMAN | null | Homo | <M><A><W><K><S><S><V><I><M><Q><M><G><R><F><L><L><L><V><I><L><F><L><P><R><E><M><T><S><S><V><L><T><V><N><G><K><T><E><N><Y><I><L><D><T><T><P><G><S><Q><A><S><L><I><C><A><V><Q><N><H><T><R><E><E><E><L><L><W><Y><R><E><E><G><R><V><D><L><K><S><G><N><K><I><N><S><S><S><V><C><V><S><S><I><S><E><N><D><N><G><I><S><F><T><C><R><L><G><R... | May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.<BOP> | Q6UXZ0 |
P78371 | TCPB_HUMAN | CCT-beta | Homo | <M><A><S><L><S><L><A><P><V><N><I><F><K><A><G><A><D><E><E><R><A><E><T><A><R><L><T><S><F><I><G><A><I><A><I><G><D><L><V><K><S><T><L><G><P><K><G><M><D><K><I><L><L><S><S><G><R><D><A><S><L><M><V><T><N><D><G><A><T><I><L><K><N><I><G><V><D><N><P><A><A><K><V><L><V><D><M><S><R><V><Q><D><D><E><V><G><D><G><T><T><S><V><T><V><L><A><A... | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis . The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance . As part of the TRiC complex may play a role in the assembly of BBSome, a comp... | P78371 |
P52799 | EFNB2_HUMAN | HTK ligand | Homo | <M><A><V><R><R><D><S><V><W><K><Y><C><W><G><V><L><M><V><L><C><R><T><A><I><S><K><S><I><V><L><E><P><I><Y><W><N><S><S><N><S><K><F><L><P><G><Q><G><L><V><L><Y><P><Q><I><G><D><K><L><D><I><I><C><P><K><V><D><S><K><T><V><G><Q><Y><E><Y><Y><K><V><Y><M><V><D><K><D><Q><A><D><R><C><T><I><K><K><E><N><T><P><L><L><N><C><A><K><P><D><Q><D... | (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.<BOP> | P52799 |
Q92947 | GCDH_HUMAN | Glutaryl-CoA dehydrogenase, mitochondrial | Homo | <M><A><L><R><G><V><S><V><R><L><L><S><R><G><P><G><L><H><V><L><R><T><W><V><S><S><A><A><Q><T><E><K><G><G><R><T><Q><S><Q><L><A><K><S><S><R><P><E><F><D><W><Q><D><P><L><V><L><E><E><Q><L><T><T><D><E><I><L><I><R><D><T><F><R><T><Y><C><Q><E><R><L><M><P><R><I><L><L><A><N><R><N><E><V><F><H><R><E><I><I><S><E><M><G><E><L><G><V><L><G... | Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.<BOP> | Q92947 |
Q7Z5L7 | PODN_HUMAN | Podocan | Homo | <M><A><Q><S><R><V><L><L><L><L><L><L><L><P><P><Q><L><H><L><G><P><V><L><A><V><R><A><P><G><F><G><R><S><G><G><H><S><L><S><P><E><E><N><E><F><A><E><E><E><P><V><L><V><L><S><P><E><E><P><G><P><G><P><A><A><V><S><C><P><R><D><C><A><C><S><Q><E><G><V><V><D><C><G><G><I><D><L><R><E><F><P><G><D><L><P><E><H><T><N><H><L><S><L><Q><N><N><Q... | Negatively regulates cell proliferation and cell migration.<BOP> | Q7Z5L7 |
P00439 | PH4H_HUMAN | Phe-4-monooxygenase | Homo | <M><S><T><A><V><L><E><N><P><G><L><G><R><K><L><S><D><F><G><Q><E><T><S><Y><I><E><D><N><C><N><Q><N><G><A><I><S><L><I><F><S><L><K><E><E><V><G><A><L><A><K><V><L><R><L><F><E><E><N><D><V><N><L><T><H><I><E><S><R><P><S><R><L><K><K><D><E><Y><E><F><F><T><H><L><D><K><R><S><L><P><A><L><T><N><I><I><K><I><L><R><H><D><I><G><A><T><V><H... | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine.<BOP> | P00439 |
Q6DKI7 | PVRIG_HUMAN | Poliovirus receptor-related immunoglobulin domain-containing protein | Homo | <M><R><T><E><A><Q><V><P><A><L><Q><P><P><E><P><G><L><E><G><A><M><G><H><R><T><L><V><L><P><W><V><L><L><T><L><C><V><T><A><G><T><P><E><V><W><V><Q><V><R><M><E><A><T><E><L><S><S><F><T><I><R><C><G><F><L><G><S><G><S><I><S><L><V><T><V><S><W><G><G><P><N><G><A><G><G><T><T><L><A><V><L><H><P><E><R><G><I><R><Q><W><A><P><A><R><Q><A><R... | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.<BOP> | Q6DKI7 |
Q96FZ7 | CHMP6_HUMAN | Vacuolar protein sorting-associated protein 20 | Homo | <M><G><N><L><F><G><R><K><K><Q><S><R><V><T><E><Q><D><K><A><I><L><Q><L><K><Q><Q><R><D><K><L><R><Q><Y><Q><K><R><I><A><Q><Q><L><E><R><E><R><A><L><A><R><Q><L><L><R><D><G><R><K><E><R><A><K><L><L><L><K><K><K><R><Y><Q><E><Q><L><L><D><R><T><E><N><Q><I><S><S><L><E><A><M><V><Q><S><I><E><F><T><Q><I><E><M><K><V><M><E><G><L><Q><F><G... | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membr... | Q96FZ7 |
Q8NGJ3 | O52E1_HUMAN | Olfactory receptor 52E1 | Homo | <M><N><T><T><L><F><H><P><Y><S><F><L><L><L><G><I><P><G><L><E><S><M><H><L><W><V><G><F><P><F><F><A><V><F><L><T><A><V><L><G><N><I><T><I><L><F><V><I><Q><T><D><S><S><L><H><H><P><M><F><Y><F><L><A><I><L><S><S><I><D><P><G><L><S><T><S><T><I><P><K><M><L><G><T><F><W><F><T><L><R><E><I><S><F><E><G><C><L><T><Q><M><F><F><I><H><L><C><T... | Odorant receptor.<BOP> | Q8NGJ3 |
Q8TDV2 | GP148_HUMAN | G-protein coupled receptor PGR6 | Homo | <M><G><D><E><L><A><P><C><P><V><G><T><T><A><W><P><A><L><I><Q><L><I><S><K><T><P><C><M><P><Q><A><A><S><N><T><S><L><G><L><G><D><L><R><V><P><S><S><M><L><Y><W><L><F><L><P><S><S><L><L><A><A><A><T><L><A><V><S><P><L><L><L><V><T><I><L><R><N><Q><R><L><R><Q><E><P><H><Y><L><L><P><A><N><I><L><L><S><D><L><A><Y><I><L><L><H><M><L><I><S... | Orphan receptor.<BOP> | Q8TDV2 |
Q6PEY0 | CXB7_HUMAN | Connexin-25 | Homo | <M><S><W><M><F><L><R><D><L><L><S><G><V><N><K><Y><S><T><G><T><G><W><I><W><L><A><V><V><F><V><F><R><L><L><V><Y><M><V><A><A><E><H><V><W><K><D><E><Q><K><E><F><E><C><N><S><R><Q><P><G><C><K><N><V><C><F><D><D><F><F><P><I><S><Q><V><R><L><W><A><L><Q><L><I><M><V><S><T><P><S><L><L><V><V><L><H><V><A><Y><H><E><G><R><E><K><R><H><R><K... | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.<BOP> | Q6PEY0 |
Q9P0K8 | FOXJ2_HUMAN | Fork head homologous X | Homo | <M><A><S><D><L><E><S><S><L><T><S><I><D><W><L><P><Q><L><T><L><R><A><T><I><E><K><L><G><S><A><S><Q><A><G><P><P><G><S><S><R><K><C><S><P><G><S><P><T><D><P><N><A><T><L><S><K><D><E><A><A><V><H><Q><D><G><K><P><R><Y><S><Y><A><T><L><I><T><Y><A><I><N><S><S><P><A><K><K><M><T><L><S><E><I><Y><R><W><I><C><D><N><F><P><Y><Y><K><N><A><G... | Transcriptional activator.<BOP> | Q9P0K8 |
Q9Y258 | CCL26_HUMAN | Thymic stroma chemokine-1 | Homo | <M><M><G><L><S><L><A><S><A><V><L><L><A><S><L><L><S><L><H><L><G><T><A><T><R><G><S><D><I><S><K><T><C><C><F><Q><Y><S><H><K><P><L><P><W><T><W><V><R><S><Y><E><F><T><S><N><S><C><S><Q><R><A><V><I><F><T><T><K><R><G><K><K><V><C><T><H><P><R><K><K><W><V><Q><K><Y><I><S><L><L><K><T><P><K><Q><L> | Chemoattractant for eosinophils and basophils . Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils . Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis .<BOP> | Q9Y258 |
Q969Q1 | TRI63_HUMAN | Tripartite motif-containing protein 63 | Homo | <M><D><Y><K><S><S><L><I><Q><D><G><N><P><M><E><N><L><E><K><Q><L><I><C><P><I><C><L><E><M><F><T><K><P><V><V><I><L><P><C><Q><H><N><L><C><R><K><C><A><N><D><I><F><Q><A><A><N><P><Y><W><T><S><R><G><S><S><V><S><M><S><G><G><R><F><R><C><P><T><C><R><H><E><V><I><M><D><R><H><G><V><Y><G><L><Q><R><N><L><L><V><E><N><I><I><D><I><Y><K><Q... | E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein s... | Q969Q1 |
Q9NXH9 | TRM1_HUMAN | tRNA(m(2,2)G26)dimethyltransferase | Homo | <M><Q><G><S><S><L><W><L><S><L><T><F><R><S><A><R><V><L><S><R><A><R><F><F><E><W><Q><S><P><G><L><P><N><T><A><A><M><E><N><G><T><G><P><Y><G><E><E><R><P><R><E><V><Q><E><T><T><V><T><E><G><A><A><K><I><A><F><P><S><A><N><E><V><F><Y><N><P><V><Q><E><F><N><R><D><L><T><C><A><V><I><T><E><F><A><R><I><Q><L><G><A><K><G><I><Q><I><K><V><P... | Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.<BOP> | Q9NXH9 |
Q99879 | H2B1M_HUMAN | Histone H2B.e | Homo | <M><P><E><P><V><K><S><A><P><V><P><K><K><G><S><K><K><A><I><N><K><A><Q><K><K><D><G><K><K><R><K><R><S><R><K><E><S><Y><S><V><Y><V><Y><K><V><L><K><Q><V><H><P><D><T><G><I><S><S><K><A><M><G><I><M><N><S><F><V><N><D><I><F><E><R><I><A><G><E><A><S><R><L><A><H><Y><N><K><R><S><T><I><T><S><R><E><I><Q><T><A><V><R><L><L><L><P><G><E><L... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | Q99879 |
P10072 | ZN875_HUMAN | Protein HKR1 | Homo | <M><R><V><N><H><T><V><S><T><M><L><P><T><C><M><V><H><R><Q><T><M><S><C><S><G><A><G><G><I><T><A><F><V><A><F><R><D><V><A><V><Y><F><T><Q><E><E><W><R><L><L><S><P><A><Q><R><T><L><H><R><E><V><M><L><E><T><Y><N><H><L><V><S><L><E><I><P><S><S><K><P><K><L><I><A><Q><L><E><R><G><E><A><P><W><R><E><E><R><K><C><P><L><D><L><C><P><E><S><K... | May be involved in transcriptional regulation.<BOP> | P10072 |
Q8N370 | LAT4_HUMAN | Solute carrier family 43 member 2 | Homo | <M><A><P><T><L><A><T><A><H><R><R><R><W><W><M><A><C><T><A><V><L><E><N><L><L><F><S><A><V><L><L><G><W><G><S><L><L><I><M><L><K><S><E><G><F><Y><S><Y><L><C><T><E><P><E><N><V><T><N><G><T><V><G><G><T><A><E><P><G><H><E><E><V><S><W><M><N><G><W><L><S><C><Q><A><Q><D><E><M><L><N><L><A><F><T><V><G><S><F><L><L><S><A><I><T><L><P><L><G... | Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids.<BOP> | Q8N370 |
P62633 | CNBP_HUMAN | Zinc finger protein 9 | Homo | <M><S><S><N><E><C><F><K><C><G><R><S><G><H><W><A><R><E><C><P><T><G><G><G><R><G><R><G><M><R><S><R><G><R><G><G><F><T><S><D><R><G><F><Q><F><V><S><S><S><L><P><D><I><C><Y><R><C><G><E><S><G><H><L><A><K><D><C><D><L><Q><E><D><A><C><Y><N><C><G><R><G><G><H><I><A><K><D><C><K><E><P><K><R><E><R><E><Q><C><C><Y><N><C><G><K><P><G><H><L... | Binds to RNA.<BOP> | P62633 |
Q96MU8 | KREM1_HUMAN | Kringle-containing protein marking the eye and the nose | Homo | <M><A><P><P><A><A><R><L><A><L><L><S><A><A><A><L><T><L><A><A><R><P><A><P><S><P><G><L><G><P><E><C><F><T><A><N><G><A><D><Y><R><G><T><Q><N><W><T><A><L><Q><G><G><K><P><C><L><F><W><N><E><T><F><Q><H><P><Y><N><T><L><K><Y><P><N><G><E><G><G><L><G><E><H><N><Y><C><R><N><P><D><G><D><V><S><P><W><C><Y><V><A><E><H><E><D><G><V><Y><W><K... | Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and... | Q96MU8 |
C9JE40 | PATL2_HUMAN | Protein PAT1 homolog a | Homo | <M><N><C><L><E><G><P><G><K><T><C><G><P><L><A><S><E><E><E><L><V><S><A><C><Q><L><E><K><E><E><E><N><E><G><E><E><E><E><E><E><E><D><E><E><D><L><D><P><D><L><D><P><D><L><E><E><E><E><N><D><L><G><D><P><A><V><L><G><A><V><H><N><T><Q><R><A><L><L><S><S><P><G><V><K><A><P><G><M><L><G><M><S><L><A><S><L><H><F><L><W><Q><T><L><D><Y><L><S... | RNA-binding protein that acts as a translational repressor.<BOP> | C9JE40 |
Q08629 | TICN1_HUMAN | Protein SPOCK | Homo | <M><P><A><I><A><V><L><A><A><A><A><A><A><W><C><F><L><Q><V><E><S><R><H><L><D><A><L><A><G><G><A><G><P><N><H><G><N><F><L><D><N><D><Q><W><L><S><T><V><S><Q><Y><D><R><D><K><Y><W><N><R><F><R><D><D><D><Y><F><R><N><W><N><P><N><K><P><F><D><Q><A><L><D><P><S><K><D><P><C><L><K><V><K><C><S><P><H><K><V><C><V><T><Q><D><Y><Q><T><A><L><C... | May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.<BOP> | Q08629 |
P16118 | F261_HUMAN | Fructose-2,6-bisphosphatase | Homo | <M><S><P><E><M><G><E><L><T><Q><T><R><L><Q><K><I><W><I><P><H><S><S><G><S><S><R><L><Q><R><R><R><G><S><S><I><P><Q><F><T><N><S><P><T><M><V><I><M><V><G><L><P><A><R><G><K><T><Y><I><S><T><K><L><T><R><Y><L><N><W><I><G><T><P><T><K><V><F><N><L><G><Q><Y><R><R><E><A><V><S><Y><K><N><Y><E><F><F><L><P><D><N><M><E><A><L><Q><I><R><K><Q... | Synthesis and degradation of fructose 2,6-bisphosphate.<BOP> | P16118 |
Q9UHY8 | FEZ2_HUMAN | Zygin-2 | Homo | <M><A><A><D><G><D><W><Q><D><F><Y><E><F><Q><E><P><A><R><S><L><L><D><Q><E><N><C><N><A><S><P><E><P><G><A><E><A><G><A><E><A><G><G><G><A><D><G><F><P><A><P><A><C><S><L><E><E><K><L><S><L><C><F><R><P><S><D><P><G><A><E><P><P><R><T><A><V><R><P><I><T><E><R><S><L><L><Q><G><D><E><I><W><N><A><L><T><D><N><Y><G><N><V><M><P><V><D><W><K... | Involved in axonal outgrowth and fasciculation.<BOP> | Q9UHY8 |
P17787 | ACHB2_HUMAN | Neuronal acetylcholine receptor subunit beta-2 | Homo | <M><A><R><R><C><G><P><V><A><L><L><L><G><F><G><L><L><R><L><C><S><G><V><W><G><T><D><T><E><E><R><L><V><E><H><L><L><D><P><S><R><Y><N><K><L><I><R><P><A><T><N><G><S><E><L><V><T><V><Q><L><M><V><S><L><A><Q><L><I><S><V><H><E><R><E><Q><I><M><T><T><N><V><W><L><T><Q><E><W><E><D><Y><R><L><T><W><K><P><E><E><F><D><N><M><K><K><V><R><L... | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.<BOP> | P17787 |
Q96EG1 | ARSG_HUMAN | N-sulfoglucosamine-3-sulfatase | Homo | <M><G><W><L><F><L><K><V><L><L><A><G><V><S><F><S><G><F><L><Y><P><L><V><D><F><C><I><S><G><K><T><R><G><Q><K><P><N><F><V><I><I><L><A><D><D><M><G><W><G><D><L><G><A><N><W><A><E><T><K><D><T><A><N><L><D><K><M><A><S><E><G><M><R><F><V><D><F><H><A><A><A><S><T><C><S><P><S><R><A><S><L><L><T><G><R><L><G><L><R><N><G><V><T><R><N><F><A... | Displays arylsulfatase activity at acidic pH towards artificial substrates, such as p-nitrocatechol sulfate and also, but with a lower activity towards p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate . Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin .<BO... | Q96EG1 |
P31150 | GDIA_HUMAN | Protein XAP-4 | Homo | <M><D><E><E><Y><D><V><I><V><L><G><T><G><L><T><E><C><I><L><S><G><I><M><S><V><N><G><K><K><V><L><H><M><D><R><N><P><Y><Y><G><G><E><S><S><S><I><T><P><L><E><E><L><Y><K><R><F><Q><L><L><E><G><P><P><E><S><M><G><R><G><R><D><W><N><V><D><L><I><P><K><F><L><M><A><N><G><Q><L><V><K><M><L><L><Y><T><E><V><T><R><Y><L><D><F><K><V><V><E><G... | Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from me... | P31150 |
A6NJL1 | ZSA5B_HUMAN | Zinc finger and SCAN domain-containing protein 5B | Homo | <M><A><A><N><W><T><L><S><W><G><Q><G><G><P><C><N><S><P><G><S><D><T><P><R><S><V><A><S><P><E><T><Q><L><G><N><H><D><R><N><P><E><T><W><H><M><N><F><R><M><F><S><C><P><E><E><S><D><P><I><Q><A><L><R><K><L><T><E><L><C><H><L><W><L><R><P><D><L><H><T><K><E><Q><I><L><D><M><L><V><M><E><Q><F><M><I><S><M><P><Q><E><L><Q><V><L><V><K><V><N... | May be involved in transcriptional regulation.<BOP> | A6NJL1 |
Q92521 | PIGB_HUMAN | Phosphatidylinositol-glycan biosynthesis class B protein | Homo | <M><R><R><P><L><S><K><C><G><M><E><P><G><G><G><D><A><S><L><T><L><H><G><L><Q><N><R><S><H><G><K><I><K><L><R><K><R><K><S><T><L><Y><F><N><T><Q><E><K><S><A><R><R><R><G><D><L><L><G><E><N><I><Y><L><L><L><F><T><I><A><L><R><I><L><N><C><F><L><V><Q><T><S><F><V><P><D><E><Y><W><Q><S><L><E><V><S><H><H><M><V><F><N><Y><G><Y><L><T><W><E... | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.<BOP> | Q92521 |
Q9C0H2 | TTYH3_HUMAN | Protein tweety homolog 3 | Homo | <M><A><G><V><S><Y><A><A><P><W><W><V><S><L><L><H><R><L><P><H><F><D><L><S><W><E><A><T><S><S><Q><F><R><P><E><D><T><D><Y><Q><Q><A><L><L><L><L><G><A><A><A><L><A><C><L><A><L><D><L><L><F><L><L><F><Y><S><F><W><L><C><C><R><R><R><K><S><E><E><H><L><D><A><D><C><C><C><T><A><W><C><V><I><I><A><T><L><V><C><S><A><G><I><A><V><G><F><Y><G... | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction.<BOP> | Q9C0H2 |
Q8NCV1 | ADAD2_HUMAN | Testis nuclear RNA-binding protein-like | Homo | <M><A><S><A><S><Q><G><A><D><D><D><G><S><R><R><K><P><R><L><A><A><S><L><Q><I><S><P><Q><P><R><P><W><R><P><L><P><A><Q><A><Q><S><A><W><G><P><A><P><A><P><A><T><Y><R><A><E><G><G><W><P><Q><V><S><V><L><R><D><S><G><P><G><A><G><A><G><V><G><E><L><G><A><A><R><A><W><E><N><L><G><E><Q><M><G><K><A><P><R><V><P><V><P><P><A><G><L><S><L><P... | Required for male fertility and normal male germ cell differentiation.<BOP> | Q8NCV1 |
O60412 | OR7C2_HUMAN | Olfactory receptor OR19-22 | Homo | <M><E><R><G><N><Q><T><E><V><G><N><F><L><L><L><G><F><A><E><D><S><D><M><Q><L><L><L><H><G><L><F><L><S><M><Y><L><V><T><I><I><G><N><L><L><I><I><L><T><I><S><S><D><S><H><L><H><T><P><M><Y><F><F><L><S><N><L><S><F><A><D><I><C><F><T><S><T><T><V><P><K><M><L><V><N><I><Q><T><Q><S><K><M><I><T><F><A><G><C><L><T><Q><I><F><F><F><I><A><F... | Odorant receptor.<BOP> | O60412 |
O95208 | EPN2_HUMAN | EPS-15-interacting protein 2 | Homo | <M><T><T><S><S><I><R><R><Q><M><K><N><I><V><N><N><Y><S><E><A><E><I><K><V><R><E><A><T><S><N><D><P><W><G><P><S><S><S><L><M><T><E><I><A><D><L><T><Y><N><V><V><A><F><S><E><I><M><S><M><V><W><K><R><L><N><D><H><G><K><N><W><R><H><V><Y><K><A><L><T><L><L><D><Y><L><I><K><T><G><S><E><R><V><A><Q><Q><C><R><E><N><I><F><A><I><Q><T><L><K... | Plays a role in the formation of clathrin-coated invaginations and endocytosis.<BOP> | O95208 |
P47890 | OR1G1_HUMAN | Olfactory receptor OR17-8 | Homo | <M><E><G><K><N><L><T><S><I><S><E><C><F><L><L><G><F><S><E><Q><L><E><E><Q><K><P><L><F><G><S><F><L><F><M><Y><L><V><T><V><A><G><N><L><L><I><I><L><V><I><I><T><D><T><Q><L><H><T><P><M><Y><F><F><L><A><N><L><S><L><A><D><A><C><F><V><S><T><T><V><P><K><M><L><A><N><I><Q><I><Q><S><Q><A><I><S><Y><S><G><C><L><L><Q><L><Y><F><F><M><L><F... | Odorant receptor.<BOP> | P47890 |
Q96C74 | ROP1L_HUMAN | AKAP-associated sperm protein | Homo | <M><P><L><P><D><T><M><F><C><A><Q><Q><I><H><I><P><P><E><L><P><D><I><L><K><Q><F><T><K><A><A><I><R><T><Q><P><A><D><V><L><R><W><S><A><G><Y><F><S><A><L><S><R><G><D><P><L><P><V><K><D><R><M><E><M><P><T><A><T><Q><K><T><D><T><G><L><T><Q><G><L><L><K><V><L><H><K><Q><C><H><H><K><R><Y><V><E><L><T><D><L><E><Q><K><W><K><N><L><C><L><P... | Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.<BOP> | Q96C74 |
O43173 | SIA8C_HUMAN | Sialyltransferase St8Sia III | Homo | <M><R><N><C><K><M><A><R><V><A><S><V><L><G><L><V><M><L><S><V><A><L><L><I><L><S><L><I><S><Y><V><S><L><K><K><E><N><I><F><T><T><P><K><Y><A><S><P><G><A><P><R><M><Y><M><F><H><A><G><F><R><S><Q><F><A><L><K><F><L><D><P><S><F><V><P><I><T><N><S><L><T><Q><E><L><Q><E><K><P><S><K><W><K><F><N><R><T><A><F><L><H><Q><R><Q><E><I><L><Q><H... | Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for sub... | O43173 |
Q6UXB1 | IGFL3_HUMAN | Insulin growth factor-like family member 3 | Homo | <M><R><P><R><C><C><I><L><A><L><V><C><W><I><T><V><F><L><L><Q><C><S><K><G><T><T><D><A><P><V><G><S><G><L><W><L><C><Q><P><T><P><R><C><G><N><K><I><Y><N><P><S><E><Q><C><C><Y><D><D><A><I><L><S><L><K><E><T><R><R><C><G><S><T><C><T><F><W><P><C><F><E><L><C><C><P><E><S><F><G><P><Q><Q><K><F><L><V><K><L><R><V><L><G><M><K><S><Q><C><H... | Potential ligand of the IGFLR1 cell membrane receptor.<BOP> | Q6UXB1 |
P07195 | LDHB_HUMAN | Renal carcinoma antigen NY-REN-46 | Homo | <M><A><T><L><K><E><K><L><I><A><P><V><A><E><E><E><A><T><V><P><N><N><K><I><T><V><V><G><V><G><Q><V><G><M><A><C><A><I><S><I><L><G><K><S><L><A><D><E><L><A><L><V><D><V><L><E><D><K><L><K><G><E><M><M><D><L><Q><H><G><S><L><F><L><Q><T><P><K><I><V><A><D><K><D><Y><S><V><T><A><N><S><K><I><V><V><V><T><A><G><V><R><Q><Q><E><G><E><S><R... | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).<BOP> | P07195 |
Q86UX7 | URP2_HUMAN | Unc-112-related protein 2 | Homo | <M><A><G><M><K><T><A><S><G><D><Y><I><D><S><S><W><E><L><R><V><F><V><G><E><E><D><P><E><A><E><S><V><T><L><R><V><T><G><E><S><H><I><G><G><V><L><L><K><I><V><E><Q><I><N><R><K><Q><D><W><S><D><H><A><I><W><W><E><Q><K><R><Q><W><L><L><Q><T><H><W><T><L><D><K><Y><G><I><L><A><D><A><R><L><F><F><G><P><Q><H><R><P><V><I><L><R><L><P><N><R... | Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.<BOP> | Q86UX7 |
Q96DG6 | CMBL_HUMAN | Carboxymethylenebutenolidase homolog | Homo | <M><A><N><E><A><Y><P><C><P><C><D><I><G><H><R><L><E><Y><G><G><L><G><R><E><V><Q><V><E><H><I><K><A><Y><V><T><K><S><P><V><D><A><G><K><A><V><I><V><I><Q><D><I><F><G><W><Q><L><P><N><T><R><Y><I><A><D><M><I><S><G><N><G><Y><T><T><I><V><P><D><F><F><V><G><Q><E><P><W><D><P><S><G><D><W><S><I><F><P><E><W><L><K><T><R><N><A><Q><K><I><D... | Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.<BOP> | Q96DG6 |
O95865 | DDAH2_HUMAN | S-phase protein | Homo | <M><G><T><P><G><E><G><L><G><R><C><S><H><A><L><I><R><G><V><P><E><S><L><A><S><G><E><G><A><G><A><G><L><P><A><L><D><L><A><K><A><Q><R><E><H><G><V><L><G><G><K><L><R><Q><R><L><G><L><Q><L><L><E><L><P><P><E><E><S><L><P><L><G><P><L><L><G><D><T><A><V><I><Q><G><D><T><A><L><I><T><R><P><W><S><P><A><R><R><P><E><V><D><G><V><R><K><A><L... | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.<BOP> | O95865 |
P60228 | EIF3E_HUMAN | eIF-3 p48 | Homo | <M><A><E><Y><D><L><T><T><R><I><A><H><F><L><D><R><H><L><V><F><P><L><L><E><F><L><S><V><K><E><I><Y><N><E><K><E><L><L><Q><G><K><L><D><L><L><S><D><T><N><M><V><D><F><A><M><D><V><Y><K><N><L><Y><S><D><D><I><P><H><A><L><R><E><K><R><T><T><V><V><A><Q><L><K><Q><L><Q><A><E><T><E><P><I><V><K><M><F><E><D><P><E><T><T><R><Q><M><Q><S><T... | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiatio... | P60228 |
P52823 | STC1_HUMAN | Stanniocalcin-1 | Homo | <M><L><Q><N><S><A><V><L><L><V><L><V><I><S><A><S><A><T><H><E><A><E><Q><N><D><S><V><S><P><R><K><S><R><V><A><A><Q><N><S><A><E><V><V><R><C><L><N><S><A><L><Q><V><G><C><G><A><F><A><C><L><E><N><S><T><C><D><T><D><G><M><Y><D><I><C><K><S><F><L><Y><S><A><A><K><F><D><T><Q><G><K><A><F><V><K><E><S><L><K><C><I><A><N><G><V><T><S><K><V... | Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.<BOP> | P52823 |
P11684 | UTER_HUMAN | Urinary protein 1 | Homo | <M><K><L><A><V><T><L><T><L><V><T><L><A><L><C><C><S><S><A><S><A><E><I><C><P><S><F><Q><R><V><I><E><T><L><L><M><D><T><P><S><S><Y><E><A><A><M><E><L><F><S><P><D><Q><D><M><R><E><A><G><A><Q><L><K><K><L><V><D><T><L><P><Q><K><P><R><E><S><I><I><K><L><M><E><K><I><A><Q><S><S><L><C><N> | Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.<BOP> | P11684 |
Q9NQ34 | TMM9B_HUMAN | Transmembrane protein 9B | Homo | <M><A><T><L><W><G><G><L><L><R><L><G><S><L><L><S><L><S><C><L><A><L><S><V><L><L><L><A><Q><L><S><D><A><A><K><N><F><E><D><V><R><C><K><C><I><C><P><P><Y><K><E><N><S><G><H><I><Y><N><K><N><I><S><Q><K><D><C><D><C><L><H><V><V><E><P><M><P><V><R><G><P><D><V><E><A><Y><C><L><R><C><E><C><K><Y><E><E><R><S><S><V><T><I><K><V><T><I><I><I... | Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways.<BOP> | Q9NQ34 |
Q3MII6 | TBC25_HUMAN | TBC1 domain family member 25 | Homo | <M><A><T><A><S><G><A><S><D><L><S><G><S><G><A><P><P><P><G><V><G><A><Q><A><A><A><A><A><E><E><E><E><R><E><V><V><R><V><R><V><K><K><C><E><S><F><L><P><P><E><F><R><S><F><A><V><D><P><Q><I><T><S><L><D><V><L><Q><H><I><L><I><R><A><F><D><L><S><G><K><K><N><F><G><I><S><Y><L><G><R><D><R><L><G><Q><E><V><Y><L><S><L><L><S><D><W><D><L><S... | Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.<BOP> | Q3MII6 |
Q9H093 | NUAK2_HUMAN | SNF1/AMP kinase-related kinase | Homo | <M><E><S><L><V><F><A><R><R><S><G><P><T><P><S><A><A><E><L><A><R><P><L><A><E><G><L><I><K><S><P><K><P><L><M><K><K><Q><A><V><K><R><H><H><H><K><H><N><L><R><H><R><Y><E><F><L><E><T><L><G><K><G><T><Y><G><K><V><K><K><A><R><E><S><S><G><R><L><V><A><I><K><S><I><R><K><D><K><I><K><D><E><Q><D><L><M><H><I><R><R><E><I><E><I><M><S><S><L... | Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activ... | Q9H093 |
Q05996 | ZP2_HUMAN | Processed zona pellucida sperm-binding protein 2 | Homo | <M><A><C><R><Q><R><G><G><S><W><S><P><S><G><W><F><N><A><G><W><S><T><Y><R><S><I><S><L><F><F><A><L><V><T><S><G><N><S><I><D><V><S><Q><L><V><N><P><A><F><P><G><T><V><T><C><D><E><R><E><I><T><V><E><F><P><S><S><P><G><T><K><K><W><H><A><S><V><V><D><P><L><G><L><D><M><P><N><C><T><Y><I><L><D><P><E><K><L><T><L><R><A><T><Y><D><N><C><T... | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy . The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor .<BOP> | Q05996 |
A6NHG4 | DDTL_HUMAN | D-dopachrome tautomerase-like protein | Homo | <M><P><F><L><E><L><D><T><N><L><P><A><N><R><V><P><A><G><L><E><K><R><L><C><A><A><A><A><S><I><L><G><K><P><A><D><R><V><N><V><T><V><R><P><G><L><A><M><A><L><S><G><S><T><E><P><C><A><Q><L><S><I><S><S><I><G><V><V><G><T><A><E><D><N><R><S><H><S><A><H><F><F><E><F><L><T><K><E><L><A><L><G><Q><D><R><F><P><T><V><L><S><T><S><P><A><A><H... | May have lyase activity.<BOP> | A6NHG4 |
Q9UNN8 | EPCR_HUMAN | Endothelial cell protein C receptor | Homo | <M><L><T><T><L><L><P><I><L><L><L><S><G><W><A><F><C><S><Q><D><A><S><D><G><L><Q><R><L><H><M><L><Q><I><S><Y><F><R><D><P><Y><H><V><W><Y><Q><G><N><A><S><L><G><G><H><L><T><H><V><L><E><G><P><D><T><N><T><T><I><I><Q><L><Q><P><L><Q><E><P><E><S><W><A><R><T><Q><S><G><L><Q><S><Y><L><L><Q><F><H><G><L><V><R><L><V><H><Q><E><R><T><L><A... | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.<BOP> | Q9UNN8 |
Q05823 | RN5A_HUMAN | Ribonuclease L | Homo | <M><E><S><R><D><H><N><N><P><Q><E><G><P><T><S><S><S><G><R><R><A><A><V><E><D><N><H><L><L><I><K><A><V><Q><N><E><D><V><D><L><V><Q><Q><L><L><E><G><G><A><N><V><N><F><Q><E><E><E><G><G><W><T><P><L><H><N><A><V><Q><M><S><R><E><D><I><V><E><L><L><L><R><H><G><A><D><P><V><L><R><K><K><N><G><A><T><P><F><I><L><A><A><I><A><G><S><V><K><L... | Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apopto... | Q05823 |
P34896 | GLYC_HUMAN | Serine methylase | Homo | <M><T><M><P><V><N><G><A><H><K><D><A><D><L><W><S><S><H><D><K><M><L><A><Q><P><L><K><D><S><D><V><E><V><Y><N><I><I><K><K><E><S><N><R><Q><R><V><G><L><E><L><I><A><S><E><N><F><A><S><R><A><V><L><E><A><L><G><S><C><L><N><N><K><Y><S><E><G><Y><P><G><Q><R><Y><Y><G><G><T><E><F><I><D><E><L><E><T><L><C><Q><K><R><A><L><Q><A><Y><K><L><D... | Interconversion of serine and glycine .<BOP> | P34896 |
Q96EQ0 | SGTB_HUMAN | Small glutamine-rich protein with tetratricopeptide repeats 2 | Homo | <M><S><S><I><K><H><L><V><Y><A><V><I><R><F><L><R><E><Q><S><Q><M><D><T><Y><T><S><D><E><Q><E><S><L><E><V><A><I><Q><C><L><E><T><V><F><K><I><S><P><E><D><T><H><L><A><V><S><Q><P><L><T><E><M><F><T><S><S><F><C><K><N><D><V><L><P><L><S><N><S><V><P><E><D><V><G><K><A><D><Q><L><K><D><E><G><N><N><H><M><K><E><E><N><Y><A><A><A><V><D><C... | Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.<BOP> | Q96EQ0 |
O75792 | RNH2A_HUMAN | Ribonuclease HI subunit A | Homo | <M><D><L><S><E><L><E><R><D><N><T><G><R><C><R><L><S><S><P><V><P><A><V><C><R><K><E><P><C><V><L><G><V><D><E><A><G><R><G><P><V><L><G><P><M><V><Y><A><I><C><Y><C><P><L><P><R><L><A><D><L><E><A><L><K><V><A><D><S><K><T><L><L><E><S><E><R><E><R><L><F><A><K><M><E><D><T><D><F><V><G><W><A><L><D><V><L><S><P><N><L><I><S><T><S><M><L><G... | Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.<BOP> | O75792 |
Q15517 | CDSN_HUMAN | S protein | Homo | <M><G><S><S><R><A><P><W><M><G><R><V><G><G><H><G><M><M><A><L><L><L><A><G><L><L><L><P><G><T><L><A><K><S><I><G><T><F><S><D><P><C><K><D><P><T><R><I><T><S><P><N><D><P><C><L><T><G><K><G><D><S><S><G><F><S><S><Y><S><G><S><S><S><S><G><S><S><I><S><S><A><R><S><S><G><G><G><S><S><G><S><S><S><G><S><S><I><A><Q><G><G><S><A><G><S><F><K... | Important for the epidermal barrier integrity.<BOP> | Q15517 |
Q8NGZ6 | OR6F1_HUMAN | Olfactory receptor OR1-38 | Homo | <M><D><T><G><N><K><T><L><P><Q><D><F><L><L><L><G><F><P><G><S><Q><T><L><Q><L><S><L><F><M><L><F><L><V><M><Y><I><L><T><V><S><G><N><V><A><I><L><M><L><V><S><T><S><H><Q><L><H><T><P><M><Y><F><F><L><S><N><L><S><F><L><E><I><W><Y><T><T><A><A><V><P><K><A><L><A><I><L><L><G><R><S><Q><T><I><S><F><T><S><C><L><L><Q><M><Y><F><V><F><S><L... | Odorant receptor.<BOP> | Q8NGZ6 |
Q9Y543 | HES2_HUMAN | Hairy and enhancer of split 2 | Homo | <M><G><L><P><R><R><A><G><D><A><A><E><L><R><K><S><L><K><P><L><L><E><K><R><R><R><A><R><I><N><Q><S><L><S><Q><L><K><G><L><I><L><P><L><L><G><R><E><N><S><N><C><S><K><L><E><K><A><D><V><L><E><M><T><V><R><F><L><Q><E><L><P><A><S><S><W><P><T><A><A><P><L><P><C><D><S><Y><R><E><G><Y><S><A><C><V><A><R><L><A><R><V><L><P><A><C><R><V><L... | Transcriptional repressor of genes that require a bHLH protein for their transcription.<BOP> | Q9Y543 |
O95045 | UPP2_HUMAN | Uridine phosphorylase 2 | Homo | <M><A><S><V><I><P><A><S><N><R><S><M><R><S><D><R><N><T><Y><V><G><K><R><F><V><H><V><K><N><P><Y><L><D><L><M><D><E><D><I><L><Y><H><L><D><L><G><T><K><T><H><N><L><P><A><M><F><G><D><V><K><F><V><C><V><G><G><S><P><N><R><M><K><A><F><A><L><F><M><H><K><E><L><G><F><E><E><A><E><E><D><I><K><D><I><C><A><G><T><D><R><Y><C><M><Y><K><T><G... | Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate . The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable). Shows broad substrate specificity and accepts ur... | O95045 |
Q8NGX2 | O2T35_HUMAN | Olfactory receptor OR1-66 | Homo | <M><G><M><E><G><L><L><Q><N><S><T><N><F><V><L><T><G><L><I><T><H><P><A><F><P><G><L><L><F><A><V><V><F><S><I><F><V><V><A><I><T><A><N><L><V><M><I><L><L><I><H><M><D><S><R><L><H><T><P><M><Y><F><L><L><S><Q><L><S><I><M><D><T><I><Y><I><C><I><T><V><P><K><M><L><Q><D><L><L><S><K><D><K><T><I><S><F><L><G><C><A><V><Q><I><F><Y><L><T><L... | Odorant receptor.<BOP> | Q8NGX2 |
P09211 | GSTP1_HUMAN | GSTP1-1 | Homo | <M><P><P><Y><T><V><V><Y><F><P><V><R><G><R><C><A><A><L><R><M><L><L><A><D><Q><G><Q><S><W><K><E><E><V><V><T><V><E><T><W><Q><E><G><S><L><K><A><S><C><L><Y><G><Q><L><P><K><F><Q><D><G><D><L><T><L><Y><Q><S><N><T><I><L><R><H><L><G><R><T><L><G><L><Y><G><K><D><Q><Q><E><A><A><L><V><D><M><V><N><D><G><V><E><D><L><R><C><K><Y><I><S><L... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) . Participates in the formation of novel hepoxilin regioisomers . Regulates negatively CDK5 activity ... | P09211 |
Q9NX63 | MIC19_HUMAN | Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 | Homo | <M><G><G><T><T><S><T><R><R><V><T><F><E><A><D><E><N><E><N><I><T><V><V><K><G><I><R><L><S><E><N><V><I><D><R><M><K><E><S><S><P><S><G><S><K><S><Q><R><Y><S><G><A><Y><G><A><S><V><S><D><E><E><L><K><R><R><V><A><E><E><L><A><L><E><Q><A><K><K><E><S><E><D><Q><K><R><L><K><Q><A><K><E><L><D><R><E><R><A><A><A><N><E><Q><L><T><R><A><I><L... | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG... | Q9NX63 |
Q86VX2 | COMD7_HUMAN | COMM domain-containing protein 7 | Homo | <M><G><R><L><H><C><T><E><D><P><V><P><E><A><V><G><G><D><M><Q><Q><L><N><Q><L><G><A><Q><Q><F><S><A><L><T><E><V><L><F><H><F><L><T><E><P><K><E><V><E><R><F><L><A><Q><L><S><E><F><A><T><T><N><Q><I><S><L><G><S><L><R><S><I><V><K><S><L><L><L><V><P><N><G><A><L><K><K><S><L><T><A><K><Q><V><Q><A><D><F><I><T><L><G><L><S><E><E><K><A><T... | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes . Associates with the NF-kappa-B complex and suppresses its transcriptional activity .<BOP> | Q86VX2 |
Q9UBT2 | SAE2_HUMAN | Ubiquitin-like modifier-activating enzyme 2 | Homo | <M><A><L><S><R><G><L><P><R><E><L><A><E><A><V><A><G><G><R><V><L><V><V><G><A><G><G><I><G><C><E><L><L><K><N><L><V><L><T><G><F><S><H><I><D><L><I><D><L><D><T><I><D><V><S><N><L><N><R><Q><F><L><F><Q><K><K><H><V><G><R><S><K><A><Q><V><A><K><E><S><V><L><Q><F><Y><P><K><A><N><I><V><A><Y><H><D><S><I><M><N><P><D><Y><N><V><E><F><F><R... | The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.<BOP> | Q9UBT2 |
Q8IY26 | PLPP6_HUMAN | Type 1 polyisoprenoid diphosphate phosphatase | Homo | <M><P><S><P><R><R><S><M><E><G><R><P><L><G><V><S><A><S><S><S><S><S><S><P><G><S><P><A><H><G><G><G><G><G><G><S><R><F><E><F><Q><S><L><L><S><S><R><A><T><A><V><D><P><T><C><A><R><L><R><A><S><E><S><P><V><H><R><R><G><S><F><P><L><A><A><A><G><P><S><Q><S><P><A><P><P><L><P><E><E><D><R><M><D><L><N><P><S><F><L><G><I><A><L><R><S><L><L... | Magnesium-independent polyisoprenoid diphosphatase that catalyzes the sequential dephosphorylation of presqualene, farnesyl, geranyl and geranylgeranyl diphosphates . Functions in the innate immune response through the dephosphorylation of presqualene diphosphate which acts as a potent inhibitor of the signaling pathwa... | Q8IY26 |
Q8NBI6 | XXLT1_HUMAN | UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase | Homo | <M><G><L><L><R><G><G><L><P><C><A><R><A><M><A><R><L><G><A><V><R><S><H><Y><C><A><L><L><L><A><A><A><L><A><V><C><A><F><Y><Y><L><G><S><G><R><E><T><F><S><S><A><T><K><R><L><K><E><A><R><A><G><A><P><A><A><P><S><P><P><A><L><E><L><A><R><G><S><V><A><P><A><P><G><A><K><A><K><S><L><E><G><G><G><A><G><P><V><D><Y><H><L><L><M><M><F><T><K... | Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose . Known targets include Notch proteins and coagulation factors, such as F9 .<BOP> | Q8NBI6 |
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