Split (3)

train · 7.69k rows

accession stringlengths 6 10	name stringlengths 8 11	Full Name stringlengths 2 102 ⌀	taxon stringclasses 1 value	sequence stringlengths 48 2.3k	function stringlengths 15 1.34k	AlphaFoldDB stringlengths 6 10
P06307	CCKN_HUMAN	Cholecystokinin-5	Homo	<M><N><S><G><V><C><L><C><V><L><M><A><V><L><A><A><G><A><L><T><Q><P><V><P><P><A><D><P><A><G><S><G><L><Q><R><A><E><E><A><P><R><R><Q><L><R><V><S><Q><R><T><D><G><E><S><R><A><H><L><G><A><L><L><A><R><Y><I><Q><Q><A><R><K><A><P><S><G><R><M><S><I><V><K><N><L><Q><N><L><D><P><S><H><R><I><S><D><R><D><Y><M><G><W><M><D><F><G><R><R><S><A><E><E><Y><E><Y><P><S>	This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.<BOP>	P06307
O95070	YIF1A_HUMAN	YIP1-interacting factor homolog A	Homo	<M><A><Y><H><S><G><Y><G><A><H><G><S><K><H><R><A><R><A><A><P><D><P><P><P><L><F><D><D><T><S><G><G><Y><S><S><Q><P><G><G><Y><P><A><T><G><A><D><V><A><F><S><V><N><H><L><L><G><D><P><M><A><N><V><A><M><A><Y><G><S><S><I><A><S><H><G><K><D><M><V><H><K><E><L><H><R><F><V><S><V><S><K><L><K><Y><F><F><A><V><D><T><A><Y><V><A><K><K><L><G><L><L><V><F><P><Y><T><H><Q><N><W><E><V><Q><Y><S><R><D><A><P><L><P><P><R><Q><D><L><N><A><P><D><L><Y><I><P><T><M><A><F><I><T><Y><V><L><L><A><G><M><A><L><G><I><Q><K><R><F><S><P><E><V><L><G><L><C><A><S><T><A><L><V><W><V><V><M><E><V><L><A><L><L><L><G><L><Y><L><A><T><V><R><S><D><L><S><T><F><H><L><L><A><Y><S><G><Y><K><Y><V><G><M><I><L><S><V><L><T><G><L><L><F><G><S><D><G><Y><Y><V><A><L><A><W><T><S><S><A><L><M><Y><F><I><V><R><S><L><R><T><A><A><L><G><P><D><S><M><G><G><P><V><P><R><Q><R><L><Q><L><Y><L><T><L><G><A><A><A><F><Q><P><L><I><I><Y><W><L><T><F><H><L><V><R>	Possible role in transport between endoplasmic reticulum and Golgi.<BOP>	O95070
Q9BRK3	MXRA8_HUMAN	Limitrin	Homo	<M><A><L><P><S><R><I><L><L><W><K><L><V><L><L><Q><S><S><A><V><L><L><H><S><G><S><S><V><P><A><A><A><G><S><S><V><V><S><E><S><A><V><S><W><E><A><G><A><R><A><V><L><R><C><Q><S><P><R><M><V><W><T><Q><D><R><L><H><D><R><Q><R><V><L><H><W><D><L><R><G><P><G><G><G><P><A><R><R><L><L><D><L><Y><S><A><G><E><Q><R><V><Y><E><A><R><D><R><G><R><L><E><L><S><A><S><A><F><D><D><G><N><F><S><L><L><I><R><A><V><E><E><T><D><A><G><L><Y><T><C><N><L><H><H><H><Y><C><H><L><Y><E><S><L><A><V><R><L><E><V><T><D><G><P><P><A><T><P><A><Y><W><D><G><E><K><E><V><L><A><V><A><R><G><A><P><A><L><L><T><C><V><N><R><G><H><V><W><T><D><R><H><V><E><E><A><Q><Q><V><V><H><W><D><R><Q><P><P><G><V><P><H><D><R><A><D><R><L><L><D><L><Y><A><S><G><E><R><R><A><Y><G><P><L><F><L><R><D><R><V><A><V><G><A><D><A><F><E><R><G><D><F><S><L><R><I><E><P><L><E><V><A><D><E><G><T><Y><S><C><H><L><H><H><H><Y><C><G><L><H><E><R><R><V><F><H><L><T><V><A><E><P><H><A><E><P><P><P><R><G><S><P><G><N><G><S><S><H><S><G><A><P><G><P><D><P><T><L><A><R><G><H><N><V><I><N><V><I><V><P><E><S><R><A><H><F><F><Q><Q><L><G><Y><V><L><A><T><L><L><L><F><I><L><L><L><V><T><V><L><L><A><A><R><R><R><R><G><G><Y><E><Y><S><D><Q><K><S><G><K><S><K><G><K><D><V><N><L><A><E><F><A><V><A><A><G><D><Q><M><L><Y><R><S><E><D><I><Q><L><D><Y><K><N><N><I><L><K><E><R><A><E><L><A><H><S><P><L><P><A><K><Y><I><D><L><D><K><G><F><R><K><E><N><C><K>	(Microbial infection) Contributes to arthritogenic alphavirus pathogenesis and acts as a receptor for these viruses.<BOP>	Q9BRK3
O95154	ARK73_HUMAN	AFB1 aldehyde reductase 2	Homo	<M><S><R><Q><L><S><R><A><R><P><A><T><V><L><G><A><M><E><M><G><R><R><M><D><A><P><T><S><A><A><V><T><R><A><F><L><E><R><G><H><T><E><I><D><T><A><F><V><Y><S><E><G><Q><S><E><T><I><L><G><G><L><G><L><R><L><G><G><S><D><C><R><V><K><I><D><T><K><A><I><P><L><F><G><N><S><L><K><P><D><S><L><R><F><Q><L><E><T><S><L><K><R><L><Q><C><P><R><V><D><L><F><Y><L><H><M><P><D><H><S><T><P><V><E><E><T><L><R><A><C><H><Q><L><H><Q><E><G><K><F><V><E><L><G><L><S><N><Y><A><A><W><E><V><A><E><I><C><T><L><C><K><S><N><G><W><I><L><P><T><V><Y><Q><G><M><Y><N><A><I><T><R><Q><V><E><T><E><L><F><P><C><L><R><H><F><G><L><R><F><Y><A><F><N><P><L><A><G><G><L><L><T><G><K><Y><K><Y><E><D><K><N><G><K><Q><P><V><G><R><F><F><G><N><T><W><A><E><M><Y><R><N><R><Y><W><K><E><H><H><F><E><G><I><A><L><V><E><K><A><L><Q><A><A><Y><G><A><S><A><P><S><M><T><S><A><T><L><R><W><M><Y><H><H><S><Q><L><Q><G><A><H><G><D><A><V><I><L><G><M><S><S><L><E><Q><L><E><Q><N><L><A><A><A><E><E><G><P><L><E><P><A><V><V><D><A><F><N><Q><A><W><H><L><V><T><H><E><C><P><N><Y><F><R>	Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.<BOP>	O95154
Q68DH5	LMBD2_HUMAN	LMBR1 domain-containing protein 2	Homo	<M><S><G><A><A><L><G><L><E><I><V><F><V><F><F><L><A><L><F><L><L><H><R><Y><G><D><F><K><K><Q><H><R><L><V><I><I><G><T><L><L><A><W><Y><L><C><F><L><I><V><F><I><L><P><L><D><V><S><T><T><I><Y><N><R><C><K><H><A><A><A><N><S><S><P><P><E><N><S><N><I><T><G><L><Y><A><T><A><N><P><V><P><S><Q><H><P><C><F><K><P><W><S><Y><I><P><D><G><I><M><P><I><F><W><R><V><V><Y><W><T><S><Q><F><L><T><W><I><L><L><P><F><M><Q><S><Y><A><R><S><G><G><F><S><I><T><G><K><I><K><T><A><L><I><E><N><A><I><Y><Y><G><T><Y><L><L><I><F><G><A><F><L><I><Y><V><A><V><N><P><H><L><H><L><E><W><N><Q><L><Q><T><I><G><I><A><A><A><N><T><W><G><L><F><L><L><V><L><L><L><G><Y><G><L><V><E><I><P><R><S><Y><W><N><G><A><K><R><G><Y><L><L><M><K><T><Y><F><K><A><A><K><L><M><T><E><K><A><D><A><E><E><N><L><E><D><A><M><E><E><V><R><K><V><N><E><S><I><K><Y><N><H><P><L><R><K><C><V><D><T><I><L><K><K><C><P><T><E><Y><Q><E><K><M><G><R><N><M><D><D><Y><E><D><F><D><E><K><H><S><I><Y><P><S><E><K><S><L><V><K><L><H><K><Q><V><I><Y><S><V><Q><R><H><R><R><T><Q><V><Q><W><Q><I><L><L><E><Q><A><F><Y><L><E><D><V><A><K><N><E><T><S><A><T><H><Q><F><V><H><T><F><Q><S><P><E><P><E><N><R><F><I><Q><Y><F><Y><N><P><T><F><E><W><Y><W><E><C><L><L><R><P><W><F><Y><K><I><L><A><V><V><L><S><I><F><S><V><I><V><V><W><S><E><C><T><F><F><S><T><T><P><V><L><S><L><F><A><V><F><I><Q><L><A><E><K><T><Y><N><Y><I><Y><I><E><I><A><C><F><L><S><I><F><F><L><S><I><C><V><Y><S><T><V><F><R><I><R><V><F><N><Y><Y><Y><L><A><S><H><H><Q><T><D><A><Y><S><L><L><F><S><G><M><L><F><C><R><L><T><P><P><L><C><L><N><F><L><G><L><T><H><M><D><S><S><I><S><H><K><N><T><Q><P><T><A><Y><T><S><I><M><G><S><M><K><V><L><S><F><I><A><D><G><F><Y><I><Y><Y><P><M><L><V><V><I><L><C><I><A><T><Y><F><S><L><G><T><R><C><L><N><L><L><G><F><Q><Q><F><M><G><D><D><D><M><T><S><D><L><V><N><E><G><K><E><L><I><R><K><E><K><R><K><R><Q><R><Q><E><E><G><E><N><R><R><R><E><W><K><E><R><Y><G><H><N><R><E><D><S><T><R><N><R><N><I><H><T><D><P><K><E><S><N><F><S><D><V><N><T><N><R><S><A><F><K><Y><T><R><A><N><N><R><T><E><R><D><R><I><E><L><L><Q><D><A><E><P><L><D><F><N><A><E><T><F><T><D><D><P><L><E><S><E><S><G><R><Y><Q><P><G><G><R><Y><L><S><M><S><R><S><D><I><F><N><D><V>	Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway . May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable).<BOP>	Q68DH5
Q96IU4	ABHEB_HUMAN	CCG1-interacting factor B	Homo	<M><A><A><S><V><E><Q><R><E><G><T><I><Q><V><Q><G><Q><A><L><F><F><R><E><A><L><P><G><S><G><Q><A><R><F><S><V><L><L><L><H><G><I><R><F><S><S><E><T><W><Q><N><L><G><T><L><H><R><L><A><Q><A><G><Y><R><A><V><A><I><D><L><P><G><L><G><H><S><K><E><A><A><A><P><A><P><I><G><E><L><A><P><G><S><F><L><A><A><V><V><D><A><L><E><L><G><P><P><V><V><I><S><P><S><L><S><G><M><Y><S><L><P><F><L><T><A><P><G><S><Q><L><P><G><F><V><P><V><A><P><I><C><T><D><K><I><N><A><A><N><Y><A><S><V><K><T><P><A><L><I><V><Y><G><D><Q><D><P><M><G><Q><T><S><F><E><H><L><K><Q><L><P><N><H><R><V><L><I><M><K><G><A><G><H><P><C><Y><L><D><K><P><E><E><W><H><T><G><L><L><D><F><L><Q><G><L><Q>	Acts as an atypical protein-lysine deacetylase in vitro . Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues . Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate . May activate transcription .<BOP>	Q96IU4
P14384	CBPM_HUMAN	Carboxypeptidase M	Homo	<M><D><F><P><C><L><W><L><G><L><L><L><P><L><V><A><A><L><D><F><N><Y><H><R><Q><E><G><M><E><A><F><L><K><T><V><A><Q><N><Y><S><S><V><T><H><L><H><S><I><G><K><S><V><K><G><R><N><L><W><V><L><V><V><G><R><F><P><K><E><H><R><I><G><I><P><E><F><K><Y><V><A><N><M><H><G><D><E><T><V><G><R><E><L><L><L><H><L><I><D><Y><L><V><T><S><D><G><K><D><P><E><I><T><N><L><I><N><S><T><R><I><H><I><M><P><S><M><N><P><D><G><F><E><A><V><K><K><P><D><C><Y><Y><S><I><G><R><E><N><Y><N><Q><Y><D><L><N><R><N><F><P><D><A><F><E><Y><N><N><V><S><R><Q><P><E><T><V><A><V><M><K><W><L><K><T><E><T><F><V><L><S><A><N><L><H><G><G><A><L><V><A><S><Y><P><F><D><N><G><V><Q><A><T><G><A><L><Y><S><R><S><L><T><P><D><D><D><V><F><Q><Y><L><A><H><T><Y><A><S><R><N><P><N><M><K><K><G><D><E><C><K><N><K><M><N><F><P><N><G><V><T><N><G><Y><S><W><Y><P><L><Q><G><G><M><Q><D><Y><N><Y><I><W><A><Q><C><F><E><I><T><L><E><L><S><C><C><K><Y><P><R><E><E><K><L><P><S><F><W><N><N><N><K><A><S><L><I><E><Y><I><K><Q><V><H><L><G><V><K><G><Q><V><F><D><Q><N><G><N><P><L><P><N><V><I><V><E><V><Q><D><R><K><H><I><C><P><Y><R><T><N><K><Y><G><E><Y><Y><L><L><L><L><P><G><S><Y><I><I><N><V><T><V><P><G><H><D><P><H><I><T><K><V><I><I><P><E><K><S><Q><N><F><S><A><L><K><K><D><I><L><L><P><F><Q><G><Q><L><D><S><I><P><V><S><N><P><S><C><P><M><I><P><L><Y><R><N><L><P><D><H><S><A><A><T><K><P><S><L><F><L><F><L><V><S><L><L><H><I><F><F><K>	Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.<BOP>	P14384
Q99962	SH3G2_HUMAN	SH3 domain-containing GRB2-like protein 2	Homo	<M><S><V><A><G><L><K><K><Q><F><H><K><A><T><Q><K><V><S><E><K><V><G><G><A><E><G><T><K><L><D><D><D><F><K><E><M><E><R><K><V><D><V><T><S><R><A><V><M><E><I><M><T><K><T><I><E><Y><L><Q><P><N><P><A><S><R><A><K><L><S><M><I><N><T><M><S><K><I><R><G><Q><E><K><G><P><G><Y><P><Q><A><E><A><L><L><A><E><A><M><L><K><F><G><R><E><L><G><D><D><C><N><F><G><P><A><L><G><E><V><G><E><A><M><R><E><L><S><E><V><K><D><S><L><D><I><E><V><K><Q><N><F><I><D><P><L><Q><N><L><H><D><K><D><L><R><E><I><Q><H><H><L><K><K><L><E><G><R><R><L><D><F><D><Y><K><K><K><R><Q><G><K><I><P><D><E><E><L><R><Q><A><L><E><K><F><D><E><S><K><E><I><A><E><S><S><M><F><N><L><L><E><M><D><I><E><Q><V><S><Q><L><S><A><L><V><Q><A><Q><L><E><Y><H><K><Q><A><V><Q><I><L><Q><Q><V><T><V><R><L><E><E><R><I><R><Q><A><S><S><Q><P><R><R><E><Y><Q><P><K><P><R><M><S><L><E><F><P><T><G><D><S><T><Q><P><N><G><G><L><S><H><T><G><T><P><K><P><S><G><V><Q><M><D><Q><P><C><C><R><A><L><Y><D><F><E><P><E><N><E><G><E><L><G><F><K><E><G><D><I><I><T><L><T><N><Q><I><D><E><N><W><Y><E><G><M><L><H><G><H><S><G><F><F><P><I><N><Y><V><E><I><L><V><A><L><P><H>	Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.<BOP>	Q99962
P43304	GPDM_HUMAN	mtGPD	Homo	<M><A><F><Q><K><A><V><K><G><T><I><L><V><G><G><G><A><L><A><T><V><L><G><L><S><Q><F><A><H><Y><R><R><K><Q><M><N><L><A><Y><V><K><A><A><D><C><I><S><E><P><V><N><R><E><P><P><S><R><E><A><Q><L><L><T><L><Q><N><T><S><E><F><D><I><L><V><I><G><G><G><A><T><G><S><G><C><A><L><D><A><V><T><R><G><L><K><T><A><L><V><E><R><D><D><F><S><S><G><T><S><S><R><S><T><K><L><I><H><G><G><V><R><Y><L><Q><K><A><I><M><K><L><D><I><E><Q><Y><R><M><V><K><E><A><L><H><E><R><A><N><L><L><E><I><A><P><H><L><S><A><P><L><P><I><M><L><P><V><Y><K><W><W><Q><L><P><Y><Y><W><V><G><I><K><L><Y><D><L><V><A><G><S><N><C><L><K><S><S><Y><V><L><S><K><S><R><A><L><E><H><F><P><M><L><Q><K><D><K><L><V><G><A><I><V><Y><Y><D><G><Q><H><N><D><A><R><M><N><L><A><I><A><L><T><A><A><R><Y><G><A><A><T><A><N><Y><M><E><V><V><S><L><L><K><K><T><D><P><Q><T><G><K><V><R><V><S><G><A><R><C><K><D><V><L><T><G><Q><E><F><D><V><R><A><K><C><V><I><N><A><T><G><P><F><T><D><S><V><R><K><M><D><D><K><D><A><A><A><I><C><Q><P><S><A><G><V><H><I><V><M><P><G><Y><Y><S><P><E><S><M><G><L><L><D><P><A><T><S><D><G><R><V><I><F><F><L><P><W><Q><K><M><T><I><A><G><T><T><D><T><P><T><D><V><T><H><H><P><I><P><S><E><E><D><I><N><F><I><L><N><E><V><R><N><Y><L><S><C><D><V><E><V><R><R><G><D><V><L><A><A><W><S><G><I><R><P><L><V><T><D><P><K><S><A><D><T><Q><S><I><S><R><N><H><V><V><D><I><S><E><S><G><L><I><T><I><A><G><G><K><W><T><T><Y><R><S><M><A><E><D><T><I><N><A><A><V><K><T><H><N><L><K><A><G><P><S><R><T><V><G><L><F><L><Q><G><G><K><D><W><S><P><T><L><Y><I><R><L><V><Q><D><Y><G><L><E><S><E><V><A><Q><H><L><A><A><T><Y><G><D><K><A><F><E><V><A><K><M><A><S><V><T><G><K><R><W><P><I><V><G><V><R><L><V><S><E><F><P><Y><I><E><A><E><V><K><Y><G><I><K><E><Y><A><C><T><A><V><D><M><I><S><R><R><T><R><L><A><F><L><N><V><Q><A><A><E><E><A><L><P><R><I><V><E><L><M><G><R><E><L><N><W><D><D><Y><K><K><Q><E><Q><L><E><T><A><R><K><F><L><Y><Y><E><M><G><Y><K><S><R><S><E><Q><L><T><D><R><S><E><I><S><L><L><P><S><D><I><D><R><Y><K><K><R><F><H><K><F><D><A><D><Q><K><G><F><I><T><I><V><D><V><Q><R><V><L><E><S><I><N><V><Q><M><D><E><N><T><L><H><E><I><L><N><E><V><D><L><N><K><N><G><Q><V><E><L><N><E><F><L><Q><L><M><S><A><I><Q><K><G><R><V><S><G><S><R><L><A><I><L><M><K><T><A><E><E><N><L><D><R><R><V><P><I><P><V><D><R><S><C><G><G><L>	Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.<BOP>	P43304
P43166	CAH7_HUMAN	Carbonic anhydrase VII	Homo	<M><T><G><H><H><G><W><G><Y><G><Q><D><D><G><P><S><H><W><H><K><L><Y><P><I><A><Q><G><D><R><Q><S><P><I><N><I><I><S><S><Q><A><V><Y><S><P><S><L><Q><P><L><E><L><S><Y><E><A><C><M><S><L><S><I><T><N><N><G><H><S><V><Q><V><D><F><N><D><S><D><D><R><T><V><V><T><G><G><P><L><E><G><P><Y><R><L><K><Q><F><H><F><H><W><G><K><K><H><D><V><G><S><E><H><T><V><D><G><K><S><F><P><S><E><L><H><L><V><H><W><N><A><K><K><Y><S><T><F><G><E><A><A><S><A><P><D><G><L><A><V><V><G><V><F><L><E><T><G><D><E><H><P><S><M><N><R><L><T><D><A><L><Y><M><V><R><F><K><G><T><K><A><Q><F><S><C><F><N><P><K><C><L><L><P><A><S><R><H><Y><W><T><Y><P><G><S><L><T><T><P><P><L><S><E><S><V><T><W><I><V><L><R><E><P><I><C><I><S><E><R><Q><M><G><K><F><R><S><L><L><F><T><S><E><D><D><E><R><I><H><M><V><N><N><F><R><P><P><Q><P><L><K><G><R><V><V><K><A><S><F><R><A>	Reversible hydration of carbon dioxide.<BOP>	P43166
Q6NV75	GP153_HUMAN	G-protein coupled receptor PGR1	Homo	<M><S><D><E><R><R><L><P><G><S><A><V><G><W><L><V><C><G><G><L><S><L><L><A><N><A><W><G><I><L><S><V><G><A><K><Q><K><K><W><K><P><L><E><F><L><L><C><T><L><A><A><T><H><M><L><N><V><A><V><P><I><A><T><Y><S><V><V><Q><L><R><R><Q><R><P><D><F><E><W><N><E><G><L><C><K><V><F><V><S><T><F><Y><T><L><T><L><A><T><C><F><S><V><T><S><L><S><Y><H><R><M><W><M><V><C><W><P><V><N><Y><R><L><S><N><A><K><K><Q><A><V><H><T><V><M><G><I><W><M><V><S><F><I><L><S><A><L><P><A><V><G><W><H><D><T><S><E><R><F><Y><T><H><G><C><R><F><I><V><A><E><I><G><L><G><F><G><V><C><F><L><L><L><V><G><G><S><V><A><M><G><V><I><C><T><A><I><A><L><F><Q><T><L><A><V><Q><V><G><R><Q><A><D><R><R><A><F><T><V><P><T><I><V><V><E><D><A><Q><G><K><R><R><S><S><I><D><G><S><E><P><A><K><T><S><L><Q><T><T><G><L><V><T><T><I><V><F><I><Y><D><C><L><M><G><F><P><V><L><V><V><S><F><S><S><L><R><A><D><A><S><A><P><W><M><A><L><C><V><L><W><C><S><V><A><Q><A><L><L><L><P><V><F><L><W><A><C><D><R><Y><R><A><D><L><K><A><V><R><E><K><C><M><A><L><M><A><N><D><E><E><S><D><D><E><T><S><L><E><G><G><I><S><P><D><L><V><L><E><R><S><L><D><Y><G><Y><G><G><D><F><V><A><L><D><R><M><A><K><Y><E><I><S><A><L><E><G><G><L><P><Q><L><Y><P><L><R><P><L><Q><E><D><K><M><Q><Y><L><Q><V><P><P><T><R><R><F><S><H><D><D><A><D><V><W><A><A><V><P><L><P><A><F><L><P><R><W><G><S><G><E><D><L><A><A><L><A><H><L><V><L><P><A><G><P><E><R><R><R><A><S><L><L><A><F><A><E><D><A><P><P><S><R><A><R><R><R><S><A><E><S><L><L><S><L><R><P><S><A><L><D><S><G><P><R><G><A><R><D><S><P><P><G><S><P><R><R><R><P><G><P><G><P><R><S><A><S><A><S><L><L><P><D><A><F><A><L><T><A><F><E><C><E><P><Q><A><L><R><R><P><P><G><P><F><P><A><A><P><A><A><P><D><G><A><D><P><G><E><A><P><T><P><P><S><S><A><Q><R><S><P><G><P><R><P><S><A><H><S><H><A><G><S><L><R><P><G><L><S><A><S><W><G><E><P><G><G><L><R><A><A><G><G><G><G><S><T><S><S><F><L><S><S><P><S><E><S><S><G><Y><A><T><L><H><S><D><S><L><G><S><A><S>	Orphan receptor.<BOP>	Q6NV75
Q5VTH2	FLTOP_HUMAN	Cilia- and flagella-associated protein 126	Homo	<M><A><T><N><Y><S><A><N><Q><Y><E><K><A><F><S><S><K><Y><L><Q><N><W><S><P><T><K><P><T><K><E><S><I><S><S><H><E><G><Y><T><Q><I><I><A><N><D><R><G><H><L><L><P><S><V><P><R><S><K><A><N><P><W><G><S><F><M><G><T><W><Q><M><P><L><K><I><P><P><A><R><V><T><L><T><S><R><T><T><A><G><A><A><S><L><T><K><W><I><Q><K><N><P><D><L><L><K><A><S><N><G><L><C><P><E><I><L><G><K><P><H><D><P><D><S><Q><K><K><L><R><K><K><S><I><T><K><T><V><Q><Q><A><R><S><P><T><I><I><P><S><S><P><A><A><N><L><N><S><P><D><E><L><Q><S><S><H><P><S><A><G><H><T><P><G><P><Q><R><P><A><K><S>	Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.<BOP>	Q5VTH2
Q7L0Y3	TM10C_HUMAN	tRNA (guanine(9)-N(1))-methyltransferase	Homo	<M><A><A><F><L><K><M><S><V><S><V><N><F><F><R><P><F><T><R><F><L><V><P><F><T><L><H><R><K><R><N><N><L><T><I><L><Q><R><Y><M><S><S><K><I><P><A><V><T><Y><P><K><N><E><S><T><P><P><S><E><E><L><E><L><D><K><W><K><T><T><M><K><S><S><V><Q><E><E><C><V><S><T><I><S><S><S><K><D><E><D><P><L><A><A><T><R><E><F><I><E><M><W><R><L><L><G><R><E><V><P><E><H><I><T><E><E><E><L><K><T><L><M><E><C><V><S><N><T><A><K><K><K><Y><L><K><Y><L><Y><T><K><E><K><V><K><K><A><R><Q><I><K><K><E><M><K><A><A><A><R><E><E><A><K><N><I><K><L><L><E><T><T><E><E><D><K><Q><K><N><F><L><F><L><R><L><W><D><R><N><M><D><I><A><M><G><W><K><G><A><Q><A><M><Q><F><G><Q><P><L><V><F><D><M><A><Y><E><N><Y><M><K><R><K><E><L><Q><N><T><V><S><Q><L><L><E><S><E><G><W><N><R><R><N><V><D><P><F><H><I><Y><F><C><N><L><K><I><D><G><A><L><H><R><E><L><V><K><R><Y><Q><E><K><W><D><K><L><L><L><T><S><T><E><K><S><H><V><D><L><F><P><K><D><S><I><I><Y><L><T><A><D><S><P><N><V><M><T><T><F><R><H><D><K><V><Y><V><I><G><S><F><V><D><K><S><M><Q><P><G><T><S><L><A><K><A><K><R><L><N><L><A><T><E><C><L><P><L><D><K><Y><L><Q><W><E><I><G><N><K><N><L><T><L><D><Q><M><I><R><I><L><L><C><L><K><N><N><G><N><W><Q><E><A><L><Q><F><V><P><K><R><K><H><T><G><F><L><E><I><S><Q><H><S><Q><E><F><I><N><R><L><K><K><A><K><T>	Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation . Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends . Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity . The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; TRMT10C/MRPP1 acting as the catalytic N(1)-methyltransferase subunit . The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 sub	Q7L0Y3
Q7Z7J7	LHPL4_HUMAN	Lipoma HMGIC fusion partner-like 4 protein	Homo	<M><L><P><S><Q><E><A><S><K><L><Y><H><E><H><Y><M><R><N><S><R><A><I><G><V><L><W><A><I><F><T><I><C><F><A><I><I><N><V><V><V><F><I><Q><P><Y><W><V><G><D><S><V><S><T><P><K><P><G><Y><F><G><L><F><H><Y><C><V><G><S><G><L><A><G><R><E><L><T><C><R><G><S><F><T><D><F><S><T><I><P><S><S><A><F><K><A><A><A><F><F><V><L><L><S><M><V><L><I><L><G><C><I><T><C><F><S><L><F><F><F><C><N><T><A><T><V><Y><K><I><C><A><W><M><Q><L><L><A><A><L><C><L><V><L><G><C><M><I><F><P><D><G><W><D><A><E><T><I><R><D><M><C><G><A><K><T><G><K><Y><S><L><G><D><C><S><V><R><W><A><Y><I><L><A><I><I><G><I><L><N><A><L><I><L><S><F><L><A><F><V><L><G><N><R><Q><T><D><L><L><Q><E><E><L><K><P><E><N><K><D><F><V><G><S><T><V><S><S><V><L><R><P><G><G><D><V><S><G><W><G><V><L><P><C><P><V><A><H><S><Q><G><P>	Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs.<BOP>	Q7Z7J7
Q14651	PLSI_HUMAN	Intestine-specific plastin	Homo	<M><E><N><S><T><T><T><I><S><R><E><E><L><E><E><L><Q><E><A><F><N><K><I><D><I><D><N><S><G><Y><V><S><D><Y><E><L><Q><D><L><F><K><E><A><S><L><P><L><P><G><Y><K><V><R><E><I><V><E><K><I><L><S><V><A><D><S><N><K><D><G><K><I><S><F><E><E><F><V><S><L><M><Q><E><L><K><S><K><D><I><S><K><T><F><R><K><I><I><N><K><R><E><G><I><T><A><I><G><G><T><S><T><I><S><S><E><G><T><Q><H><S><Y><S><E><E><E><K><V><A><F><V><N><W><I><N><K><A><L><E><N><D><P><D><C><K><H><L><I><P><M><N><P><N><D><D><S><L><F><K><S><L><A><D><G><I><L><L><C><K><M><I><N><L><S><E><P><D><T><I><D><E><R><A><I><N><K><K><K><L><T><P><F><T><I><S><E><N><L><N><L><A><L><N><S><A><S><A><I><G><C><T><V><V><N><I><G><A><S><D><L><K><E><G><K><P><H><L><V><L><G><L><L><W><Q><I><I><K><V><G><L><F><A><D><I><E><I><S><R><N><E><A><L><I><A><L><L><N><E><G><E><E><L><E><E><L><M><K><L><S><P><E><E><L><L><L><R><W><V><N><Y><H><L><T><N><A><G><W><H><T><I><S><N><F><S><Q><D><I><K><D><S><R><A><Y><F><H><L><L><N><Q><I><A><P><K><G><G><E><D><G><P><A><I><A><I><D><L><S><G><I><N><E><T><N><D><L><K><R><A><G><L><M><L><Q><E><A><D><K><L><G><C><K><Q><F><V><T><P><A><D><V><V><S><G><N><P><K><L><N><L><A><F><V><A><N><L><F><N><T><Y><P><C><L><H><K><P><N><N><N><D><I><D><M><N><L><L><E><G><E><S><K><E><E><R><T><F><R><N><W><M><N><S><L><G><V><N><P><Y><I><N><H><L><Y><S><D><L><A><D><A><L><V><I><F><Q><L><Y><E><M><I><R><V><P><V><N><W><S><H><V><N><K><P><P><Y><P><A><L><G><G><N><M><K><K><I><E><N><C><N><Y><A><V><E><L><G><K><N><K><A><K><F><S><L><V><G><I><A><G><Q><D><L><N><E><G><N><S><T><L><T><L><A><L><V><W><Q><L><M><R><R><Y><T><L><N><V><L><S><D><L><G><E><G><E><K><V><N><D><E><I><I><I><K><W><V><N><Q><T><L><K><S><A><N><K><K><T><S><I><S><S><F><K><D><K><S><I><S><T><S><L><P><V><L><D><L><I><D><A><I><A><P><N><A><V><R><Q><E><M><I><R><R><E><N><L><S><D><E><D><K><L><N><N><A><K><Y><A><I><S><V><A><R><K><I><G><A><R><I><Y><A><L><P><D><D><L><V><E><V><K><P><K><M><V><M><T><V><F><A><C><L><M><G><K><G><L><N><R><I><K>	Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.<BOP>	Q14651
Q8NCP5	ZBT44_HUMAN	Zinc finger protein 851	Homo	<M><G><V><K><T><F><T><H><S><S><S><S><H><S><Q><E><M><L><G><K><L><N><M><L><R><N><D><G><H><F><C><D><I><T><I><R><V><Q><D><K><I><F><R><A><H><K><V><V><L><A><A><C><S><D><F><F><R><T><K><L><V><G><Q><A><E><D><E><N><K><N><V><L><D><L><H><H><V><T><V><T><G><F><I><P><L><L><E><Y><A><Y><T><A><T><L><S><I><N><T><E><N><I><I><D><V><L><A><A><A><S><Y><M><Q><M><F><S><V><A><S><T><C><S><E><F><M><K><S><S><I><L><W><N><T><P><N><S><Q><P><E><K><G><L><D><A><G><Q><E><N><N><S><N><C><N><F><T><S><R><D><G><S><I><S><P><V><S><S><E><C><S><V><V><E><R><T><I><P><V><C><R><E><S><R><R><K><R><K><S><Y><I><V><M><S><P><E><S><P><V><K><C><G><T><Q><T><S><S><P><Q><V><L><N><S><S><A><S><Y><S><E><N><R><N><Q><P><V><D><S><S><L><A><F><P><W><T><F><P><F><G><I><D><R><R><I><Q><P><E><K><V><K><Q><A><E><N><T><R><T><L><E><L><P><G><P><S><E><T><G><R><R><M><A><D><Y><V><T><C><E><S><T><K><T><T><L><P><L><G><T><E><E><D><V><R><V><K><V><E><R><L><S><D><E><E><V><H><E><E><V><S><Q><P><V><S><A><S><Q><S><S><L><S><D><Q><Q><T><V><P><G><S><E><Q><V><Q><E><D><L><L><I><S><P><Q><S><S><S><I><G><S><V><D><E><G><V><S><E><G><L><P><T><L><Q><S><T><S><S><T><N><A><P><P><D><D><D><D><R><L><E><N><V><Q><Y><P><Y><Q><L><Y><I><A><P><S><T><S><S><T><E><R><P><S><P><N><G><P><D><R><P><F><Q><C><P><T><C><G><V><R><F><T><R><I><Q><N><L><K><Q><H><M><L><I><H><S><G><I><K><P><F><Q><C><D><R><C><G><K><K><F><T><R><A><Y><S><L><K><M><H><R><L><K><H><E><G><K><R><C><F><R><C><Q><I><C><S><A><T><F><T><S><F><G><E><Y><K><H><H><M><R><V><S><R><H><I><I><R><K><P><R><I><Y><E><C><K><T><C><G><A><M><L><T><N><S><G><N><L><I><V><H><L><R><S><L><N><H><E><A><S><E><L><A><N><Y><F><Q><S><S><D><F><L><V><P><D><Y><L><N><Q><E><Q><E><E><T><L><V><Q><Y><D><L><G><E><H><G><F><E><S><N><S><S><V><Q><M><P><V><I><S><Q><Y><H><S><K><G><K><E><P>	May be involved in transcriptional regulation.<BOP>	Q8NCP5
Q9BRY0	S39A3_HUMAN	Zrt- and Irt-like protein 3	Homo	<M><V><K><L><L><V><A><K><I><L><C><M><V><G><V><F><F><F><M><L><L><G><S><L><L><P><V><K><I><I><E><T><D><F><E><K><A><H><R><S><K><K><I><L><S><L><C><N><T><F><G><G><G><V><F><L><A><T><C><F><N><A><L><L><P><A><V><R><E><K><L><Q><K><V><L><S><L><G><H><I><S><T><D><Y><P><L><A><E><T><I><L><L><L><G><F><F><M><T><V><F><L><E><Q><L><I><L><T><F><R><K><E><K><P><S><F><I><D><L><E><T><F><N><A><G><S><D><V><G><S><D><S><E><Y><E><S><P><F><M><G><G><A><R><G><H><A><L><Y><V><E><P><H><G><H><G><P><S><L><S><V><Q><G><L><S><R><A><S><P><V><R><L><L><S><L><A><F><A><L><S><A><H><S><V><F><E><G><L><A><L><G><L><Q><E><E><G><E><K><V><V><S><L><F><V><G><V><A><V><H><E><T><L><V><A><V><A><L><G><I><S><M><A><R><S><A><M><P><L><R><D><A><A><K><L><A><V><T><V><S><A><M><I><P><L><G><I><G><L><G><L><G><I><E><S><A><Q><G><V><P><G><S><V><A><S><V><L><L><Q><G><L><A><G><G><T><F><L><F><I><T><F><L><E><I><L><A><K><E><L><E><E><K><S><D><R><L><L><K><V><L><F><L><V><L><G><Y><T><V><L><A><G><M><V><F><L><K><W>	Acts as a zinc-influx transporter.<BOP>	Q9BRY0
Q9BY27	DGC6L_HUMAN	DiGeorge syndrome critical region 6-like protein	Homo	<M><E><R><Y><A><A><A><L><E><E><V><A><D><G><A><R><Q><Q><E><R><H><Y><Q><L><L><S><A><L><Q><S><L><V><K><E><L><P><S><S><F><Q><Q><R><L><S><Y><T><T><L><S><D><L><A><L><A><L><L><D><G><T><V><F><E><I><V><Q><G><L><L><E><I><Q><H><L><T><E><K><S><L><Y><N><Q><R><L><R><L><Q><N><E><H><R><V><L><R><Q><A><L><R><Q><K><H><Q><E><A><Q><Q><A><C><R><P><H><N><L><P><V><V><Q><A><A><Q><Q><R><E><L><E><A><V><E><H><R><I><R><E><E><Q><R><A><M><D><Q><K><I><I><L><E><L><D><R><K><V><A><D><Q><Q><S><T><L><E><K><A><G><V><A><G><F><Y><V><T><T><N><P><Q><E><L><M><L><Q><M><N><L><L><E><L><I><R><K><L><Q><Q><R><G><C><R><A><G><N><A><A><L><G><L><G><G><P><W><Q><S><P><A><A><Q><C><D><Q><K><G><S><P><V><P><P>	May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.<BOP>	Q9BY27
P20962	PTMS_HUMAN	Parathymosin	Homo	<M><S><E><K><S><V><E><A><A><A><E><L><S><A><K><D><L><K><E><K><K><E><K><V><E><E><K><A><S><R><K><E><R><K><K><E><V><V><E><E><E><E><N><G><A><E><E><E><E><E><E><T><A><E><D><G><E><E><E><D><E><G><E><E><E><D><E><E><E><E><E><E><D><D><E><G><P><A><L><K><R><A><A><E><E><E><D><E><A><D><P><K><R><Q><K><T><E><N><G><A><S><A>	Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.<BOP>	P20962
Q8NGT9	OR2A1_HUMAN	Olfactory receptor OR7-19	Homo	<M><G><E><N><Q><T><M><V><T><E><F><L><L><L><G><F><L><L><G><P><R><I><Q><M><L><L><F><G><L><F><S><L><F><Y><I><F><T><L><L><G><N><G><A><I><L><G><L><I><S><L><D><S><R><L><H><T><P><M><Y><F><F><L><S><H><L><A><V><V><D><I><A><Y><T><R><N><T><V><P><Q><M><L><A><N><L><L><H><P><A><K><P><I><S><F><A><G><C><M><T><Q><T><F><L><C><L><S><F><G><H><S><E><C><L><L><L><V><L><M><S><Y><D><R><Y><V><A><I><C><H><P><L><R><Y><S><V><I><M><T><W><R><V><C><I><T><L><A><V><T><S><W><T><C><G><S><L><L><A><L><A><H><V><V><L><I><L><R><L><P><F><S><G><P><H><E><I><N><H><F><F><C><E><I><L><S><V><L><R><L><A><C><A><D><T><W><L><N><Q><V><V><I><F><A><A><C><V><F><F><L><V><G><P><P><S><L><V><L><V><S><Y><S><H><I><L><A><A><I><L><R><I><Q><S><G><E><G><R><R><K><A><F><S><T><C><S><S><H><L><C><V><V><G><L><F><F><G><S><A><I><I><M><Y><M><A><P><K><S><R><H><P><E><E><Q><Q><K><V><F><F><L><F><Y><S><F><F><N><P><T><L><N><P><L><I><Y><S><L><R><N><G><E><V><K><G><A><L><R><R><A><L><G><K><E><S><H><S>	Odorant receptor.<BOP>	Q8NGT9
Q8WXI3	ASB10_HUMAN	Ankyrin repeat and SOCS box protein 10	Homo	<M><L><M><S><W><S><P><E><E><C><K><G><Q><G><E><P><L><D><D><R><H><P><L><C><A><R><L><V><E><K><P><S><R><G><S><E><E><H><L><K><S><G><P><G><P><I><V><T><R><T><A><S><G><P><A><L><A><F><W><Q><A><V><L><A><G><D><V><G><C><V><S><R><I><L><A><D><S><S><T><G><L><A><P><D><S><V><F><D><T><S><D><P><E><R><W><R><D><F><R><F><N><I><R><A><L><R><L><W><S><L><T><Y><E><E><E><L><T><T><P><L><H><V><A><A><S><R><G><H><T><E><V><L><R><L><L><L><R><R><R><A><R><P><D><S><A><P><G><G><R><T><A><L><H><E><A><C><A><A><G><H><T><A><C><V><H><V><L><L><V><A><G><A><D><P><N><I><A><D><Q><D><G><K><R><P><L><H><L><C><R><G><P><G><T><L><E><C><A><E><L><L><L><R><F><G><A><R><V><D><G><R><S><E><E><E><E><E><T><P><L><H><V><A><A><R><L><G><H><V><E><L><A><D><L><L><L><R><R><G><A><C><P><D><A><R><N><A><E><G><W><T><P><L><L><A><A><C><D><V><R><C><Q><S><I><T><D><A><E><A><T><T><A><R><C><L><Q><L><C><S><L><L><L><S><A><G><A><D><A><D><A><A><D><Q><D><K><Q><R><P><L><H><L><A><C><R><R><G><H><A><A><V><V><E><L><L><L><S><C><G><V><S><A><N><T><M><D><Y><G><G><H><T><P><L><H><C><A><L><Q><G><P><A><A><A><L><A><Q><S><P><E><H><V><V><R><A><L><L><N><H><G><A><V><R><V><W><P><G><A><L><P><K><V><L><E><R><W><S><T><C><P><R><T><I><E><V><L><M><N><T><Y><S><V><V><Q><L><P><E><E><A><V><G><L><V><T><P><E><T><L><Q><K><H><Q><R><F><Y><S><S><L><F><A><L><V><R><Q><P><R><S><L><Q><H><L><S><R><C><A><L><R><S><H><L><E><G><S><L><P><Q><A><L><P><R><L><P><L><P><P><R><L><L><R><Y><L><Q><L><D><F><E><G><V><L><Y>	May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP>	Q8WXI3
Q8N726	ARF_HUMAN	p14ARF	Homo	<M><V><R><R><F><L><V><T><L><R><I><R><R><A><C><G><P><P><R><V><R><V><F><V><V><H><I><P><R><L><T><G><E><W><A><A><P><G><A><P><A><A><V><A><L><V><L><M><L><L><R><S><Q><R><L><G><Q><Q><P><L><P><R><R><P><G><H><D><D><G><Q><R><P><S><G><G><A><A><A><A><P><R><R><G><A><Q><L><R><R><P><R><H><S><H><P><T><R><A><R><R><C><P><G><G><L><P><G><H><A><G><G><A><A><P><G><R><G><A><A><G><R><A><R><C><L><G><P><S><A><R><G><P><G>	May be involved in regulation of autophagy and caspase-independent cell death; the short-lived mitochondrial isoform is stabilized by C1QBP.<BOP>	Q8N726
Q13477	MADCA_HUMAN	Mucosal addressin cell adhesion molecule 1	Homo	<M><D><F><G><L><A><L><L><L><A><G><L><L><G><L><L><L><G><Q><S><L><Q><V><K><P><L><Q><V><E><P><P><E><P><V><V><A><V><A><L><G><A><S><R><Q><L><T><C><R><L><A><C><A><D><R><G><A><S><V><Q><W><R><G><L><D><T><S><L><G><A><V><Q><S><D><T><G><R><S><V><L><T><V><R><N><A><S><L><S><A><A><G><T><R><V><C><V><G><S><C><G><G><R><T><F><Q><H><T><V><Q><L><L><V><Y><A><F><P><D><Q><L><T><V><S><P><A><A><L><V><P><G><D><P><E><V><A><C><T><A><H><K><V><T><P><V><D><P><N><A><L><S><F><S><L><L><V><G><G><Q><E><L><E><G><A><Q><A><L><G><P><E><V><Q><E><E><E><E><E><P><Q><G><D><E><D><V><L><F><R><V><T><E><R><W><R><L><P><P><L><G><T><P><V><P><P><A><L><Y><C><Q><A><T><M><R><L><P><G><L><E><L><S><H><R><Q><A><I><P><V><L><H><S><P><T><S><P><E><P><P><D><T><T><S><P><E><S><P><D><T><T><S><P><E><S><P><D><T><T><S><Q><E><P><P><D><T><T><S><P><E><P><P><D><K><T><S><P><E><P><A><P><Q><Q><G><S><T><H><T><P><R><S><P><G><S><T><R><T><R><R><P><E><I><S><Q><A><G><P><T><Q><G><E><V><I><P><T><G><S><S><K><P><A><G><D><Q><L><P><A><A><L><W><T><S><S><A><V><L><G><L><L><L><L><A><L><P><T><Y><H><L><W><K><R><C><R><H><L><A><E><D><D><T><H><P><P><A><S><L><R><L><L><P><Q><V><S><A><W><A><G><L><R><G><T><G><Q><V><G><I><S><P><S>	Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.<BOP>	Q13477
Q8WTP8	AEN_HUMAN	Interferon-stimulated 20 kDa exonuclease-like 1	Homo	<M><V><P><R><E><A><P><E><S><A><Q><C><L><C><P><S><L><T><I><P><N><A><K><D><V><L><R><K><R><H><K><R><R><S><R><Q><H><Q><R><F><M><A><R><K><A><L><L><Q><E><Q><G><L><L><S><M><P><P><E><P><G><S><S><P><L><P><T><P><F><G><A><A><T><A><T><E><A><A><S><S><G><K><Q><C><L><R><A><G><S><G><S><A><P><C><S><R><R><P><A><P><G><K><A><S><G><P><L><P><S><K><C><V><A><I><D><C><E><M><V><G><T><G><P><R><G><R><V><S><E><L><A><R><C><S><I><V><S><Y><H><G><N><V><L><Y><D><K><Y><I><R><P><E><M><P><I><A><D><Y><R><T><R><W><S><G><I><T><R><Q><H><M><R><K><A><V><P><F><Q><V><A><Q><K><E><I><L><K><L><L><K><G><K><V><V><V><G><H><A><L><H><N><D><F><Q><A><L><K><Y><V><H><P><R><S><Q><T><R><D><T><T><Y><V><P><N><F><L><S><E><P><G><L><H><T><R><A><R><V><S><L><K><D><L><A><L><Q><L><L><H><K><K><I><Q><V><G><Q><H><G><H><S><S><V><E><D><A><T><T><A><M><E><L><Y><R><L><V><E><V><Q><W><E><Q><Q><E><A><R><S><L><W><T><C><P><E><D><R><E><P><D><S><S><T><D><M><E><Q><Y><M><E><D><Q><Y><W><P><D><D><L><A><H><G><S><R><G><G><A><R><E><A><Q><D><R><R><N>	Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.<BOP>	Q8WTP8
Q9Y2D9	ZN652_HUMAN	Zinc finger protein 652	Homo	<M><S><H><T><A><S><S><C><Q><E><L><V><E><N><C><A><V><H><V><A><G><M><A><Q><E><D><S><R><R><G><Q><V><P><S><S><F><Y><H><G><A><N><Q><E><L><D><L><S><T><K><V><Y><K><R><E><S><G><S><P><Y><S><V><L><V><D><T><K><M><S><K><P><H><L><H><E><T><E><E><Q><P><Y><F><R><E><T><R><A><V><S><D><V><H><A><V><K><E><D><R><E><N><S><D><D><T><E><E><E><E><E><E><V><S><Y><K><R><E><Q><I><I><V><E><V><N><L><N><N><Q><T><L><N><V><S><K><G><E><K><G><V><S><S><Q><S><K><E><T><P><V><L><K><T><S><S><E><E><E><E><E><E><S><E><E><E><A><T><D><D><S><N><D><Y><G><E><N><E><K><Q><K><K><K><E><K><I><V><E><K><V><S><V><T><Q><R><R><T><R><R><A><A><S><V><A><A><A><T><T><S><P><T><P><R><T><T><R><G><R><R><K><S><V><E><P><P><K><R><K><K><R><A><T><K><E><P><K><A><P><V><Q><K><A><K><C><E><E><K><E><T><L><T><C><E><K><C><P><R><V><F><N><T><R><W><Y><L><E><K><H><M><N><V><T><H><R><R><M><Q><I><C><D><K><C><G><K><K><F><V><L><E><S><E><L><S><L><H><Q><Q><T><D><C><E><K><N><I><Q><C><V><S><C><N><K><S><F><K><K><L><W><S><L><H><E><H><I><K><I><V><H><G><Y><A><E><K><K><F><S><C><E><I><C><E><K><K><F><Y><T><M><A><H><V><R><K><H><M><V><A><H><T><K><D><M><P><F><T><C><E><T><C><G><K><S><F><K><R><S><M><S><L><K><V><H><S><L><Q><H><S><G><E><K><P><F><R><C><E><N><C><D><E><R><F><Q><Y><K><Y><Q><L><R><S><H><M><S><I><H><I><G><H><K><Q><F><M><C><Q><W><C><G><K><D><F><N><M><K><Q><Y><F><D><E><H><M><K><T><H><T><G><E><K><P><F><I><C><E><I><C><G><K><S><F><T><S><R><P><N><M><K><R><H><R><R><T><H><T><G><E><K><P><Y><P><C><D><V><C><G><Q><R><F><R><F><S><N><M><L><K><A><H><K><E><K><C><F><R><V><T><S><P><V><N><V><P><P><A><V><Q><I><P><L><T><T><S><P><A><T><P><V><P><S><V><V><N><T><A><T><T><P><T><P><P><I><N><M><N><P><V><S><T><L><P><P><R><P><I><P><H><P><F><S><H><L><H><I><H><P><H><P><H><H><P><H><H><L><P><I><P><P><V><P><H><L><P><P><P><P><A><L><F><K><S><E><P><L><N><H><R><G><Q><S><E><D><N><F><L><R><H><L><A><E><K><N><S><S><A><Q><H><H>	Functions as a transcriptional repressor.<BOP>	Q9Y2D9
Q7Z3T1	OR2W3_HUMAN	Olfactory receptor OR1-49	Homo	<M><D><G><T><N><G><S><T><Q><T><H><F><I><L><L><G><F><S><D><R><P><H><L><E><R><I><L><F><V><V><I><L><I><A><Y><L><L><T><L><V><G><N><T><T><I><I><L><V><S><R><L><D><P><H><L><H><T><P><M><Y><F><F><L><A><H><L><S><F><L><D><L><S><F><T><T><S><S><I><P><Q><L><L><Y><N><L><N><G><C><D><K><T><I><S><Y><M><G><C><A><I><Q><L><F><L><F><L><G><L><G><G><V><E><C><L><L><L><A><V><M><A><Y><D><R><C><V><A><I><C><K><P><L><H><Y><M><V><I><M><N><P><R><L><C><R><G><L><V><S><V><T><W><G><C><G><V><A><N><S><L><A><M><S><P><V><T><L><R><L><P><R><C><G><H><H><E><V><D><H><F><L><R><E><M><P><A><L><I><R><M><A><C><V><S><T><V><A><I><E><G><T><V><F><V><L><A><V><G><V><V><L><S><P><L><V><F><I><L><L><S><Y><S><Y><I><V><R><A><V><L><Q><I><R><S><A><S><G><R><Q><K><A><F><G><T><C><G><S><H><L><T><V><V><S><L><F><Y><G><N><I><I><Y><M><Y><M><Q><P><G><A><S><S><S><Q><D><Q><G><M><F><L><M><L><F><Y><N><I><V><T><P><L><L><N><P><L><I><Y><T><L><R><N><R><E><V><K><G><A><L><G><R><L><L><L><G><K><R><E><L><G><K><E>	Odorant receptor.<BOP>	Q7Z3T1
Q5VUJ5	AGAP7_HUMAN	Centaurin-gamma-like family member 4	Homo	<M><G><N><I><L><T><C><R><V><H><P><S><V><S><L><E><F><D><Q><Q><Q><G><S><V><C><P><S><E><S><E><I><Y><E><A><G><A><E><D><R><M><A><G><A><P><M><A><A><A><V><Q><P><A><E><V><T><V><E><V><G><E><D><L><H><M><H><H><V><R><D><R><E><M><P><E><A><L><E><F><N><P><S><A><N><P><E><A><S><T><I><F><Q><R><N><S><Q><T><D><V><V><E><I><R><R><S><N><C><T><N><H><V><S><T><V><H><F><S><Q><Q><Y><S><L><C><S><T><I><F><L><D><D><S><T><A><I><Q><H><Y><L><T><M><T><I><I><S><V><T><L><E><I><P><H><H><I><T><Q><R><D><A><D><R><S><L><S><I><P><D><E><Q><L><H><S><F><A><V><S><T><V><H><I><T><K><N><R><N><G><G><G><S><L><N><N><Y><S><S><S><I><P><S><T><P><S><T><S><Q><E><D><P><Q><F><S><V><P><P><T><A><N><T><P><T><P><V><C><K><R><S><M><R><W><S><N><L><F><T><S><E><K><G><S><D><P><D><K><E><R><K><A><P><E><N><H><A><D><T><I><G><S><G><R><A><I><P><I><K><Q><G><M><L><L><K><R><S><G><K><W><L><K><T><W><K><K><K><Y><V><T><L><C><S><N><G><V><L><T><Y><Y><S><S><L><G><D><Y><M><K><Y><I><H><K><K><E><I><D><L><Q><T><S><T><I><K><V><P><G><K><W><P><S><L><A><T><L><A><C><T><P><I><S><S><S><K><S><D><G><L><S><K><D><M><D><T><G><L><G><D><S><I><C><F><S><P><S><I><S><S><T><T><I><P><K><L><N><P><P><P><S><P><H><A><N><K><K><K><H><L><K><K><K><S><T><N><N><F><M><I><V><S><A><T><G><Q><T><W><H><F><E><A><T><T><Y><E><E><R><D><A><W><V><Q><A><I><Q><S><Q><I><L><A><S><L><Q><S><C><E><S><S><K><S><K><S><Q><L><T><S><Q><S><E><A><M><A><L><Q><S><I><Q><N><M><R><G><N><A><H><C><V><D><C><E><T><Q><N><P><K><W><A><S><L><N><L><G><V><L><M><C><I><E><C><S><G><I><H><R><S><L><G><T><R><L><S><R><V><R><S><L><E><L><D><D><W><P><V><E><L><R><K><V><M><S><S><I><G><N><D><L><A><N><S><I><W><E><G><S><S><Q><G><R><T><K><P><T><E><K><S><T><R><E><E><K><E><R><W><I><R><S><K><Y><E><E><K><L><F><L><A><P><L><P><C><T><E><L><S><L><G><Q><Q><L><L><R><A><T><A><D><E><D><L><Q><T><A><I><L><L><L><A><H><G><S><R><E><E><V><N><E><T><C><G><E><G><D><G><C><T><A><L><H><L><A><C><R><K><G><N><V><V><L><A><Q><L><L><I><W><Y><G><V><D><V><M><A><R><D><A><H><G><N><T><A><L><T><Y><A><R><Q><A><S><S><Q><E><C><I><N><V><L><L><Q><Y><G><C><P><D><E><C><V>	Putative GTPase-activating protein.<BOP>	Q5VUJ5
Q86YJ7	AN13B_HUMAN	Ankyrin repeat domain-containing protein 13B	Homo	<M><I><P><A><N><A><S><A><R><K><G><P><E><G><K><Y><P><L><H><Y><L><V><W><H><N><R><H><R><E><L><E><K><E><V><R><A><G><Q><V><D><I><E><Q><L><D><P><R><G><R><T><P><L><H><L><A><T><T><L><G><H><L><E><C><A><R><V><L><L><A><H><G><A><D><V><G><R><E><N><R><S><G><W><T><V><L><Q><E><A><V><S><T><R><D><L><E><L><V><Q><L><V><L><R><Y><R><D><Y><Q><R><V><V><K><R><L><A><G><I><P><V><L><L><E><K><L><R><K><A><Q><D><F><Y><V><E><M><K><W><E><F><T><S><W><V><P><L><V><S><K><I><C><P><S><D><T><Y><K><V><W><K><S><G><Q><N><L><R><V><D><T><T><L><L><G><F><D><H><M><T><W><Q><R><G><N><R><S><F><V><F><R><G><Q><D><T><S><A><V><V><M><E><I><D><H><D><R><R><V><V><Y><T><E><T><L><A><L><A><G><Q><D><R><E><L><L><L><A><A><A><Q><P><T><E><E><Q><V><L><S><R><L><T><A><P><V><V><T><T><Q><L><D><T><K><N><I><S><F><E><R><N><K><T><G><I><L><G><W><R><S><E><K><T><E><M><V><N><G><Y><E><A><K><V><Y><G><A><S><N><V><E><L><I><T><R><T><R><T><E><H><L><S><E><Q><H><K><G><K><V><K><G><C><K><T><P><L><Q><S><F><L><G><I><A><E><Q><H><G><G><P><Q><N><G><T><L><I><T><Q><T><L><S><Q><A><N><P><T><A><I><T><A><E><E><Y><F><N><P><N><F><E><L><G><N><R><D><M><G><R><P><M><E><L><T><T><K><T><Q><K><F><K><A><K><L><W><L><C><E><E><H><P><L><S><L><C><E><Q><V><A><P><I><I><D><L><M><A><V><S><N><A><L><F><A><K><L><R><D><F><I><T><L><R><L><P><P><G><F><P><V><K><I><E><I><P><I><F><H><I><L><N><A><R><I><T><F><G><N><L><N><G><C><D><E><P><V><P><S><V><R><G><S><P><S><S><E><T><P><S><P><G><S><D><S><S><S><V><S><S><S><S><S><T><T><S><C><R><G><C><E><I><S><P><A><L><F><E><A><P><R><G><Y><S><M><M><G><G><Q><R><E><A><A><T><R><D><D><D><D><D><L><L><Q><F><A><I><Q><Q><S><L><L><E><A><G><S><E><Y><D><Q><V><T><I><W><E><A><L><T><N><S><K><P><G><T><H><P><M><S><Y><E><G><R><R><Q><D><R><S><A><P><P><T><P><Q><R><Q><P><A><P><P><A><S><V><P><S><P><R><P><S><S><G><P><G><S><G><G><H><V><F><R><S><Y><D><E><Q><L><R><L><A><M><E><L><S><A><Q><E><Q><E><E><R><R><R><R><A><R><Q><E><E><E><E><L><E><R><I><L><R><L><S><L><T><E><Q>	Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.<BOP>	Q86YJ7
O95292	VAPB_HUMAN	Vesicle-associated membrane protein-associated protein B/C	Homo	<M><A><K><V><E><Q><V><L><S><L><E><P><Q><H><E><L><K><F><R><G><P><F><T><D><V><V><T><T><N><L><K><L><G><N><P><T><D><R><N><V><C><F><K><V><K><T><T><A><P><R><R><Y><C><V><R><P><N><S><G><I><I><D><A><G><A><S><I><N><V><S><V><M><L><Q><P><F><D><Y><D><P><N><E><K><S><K><H><K><F><M><V><Q><S><M><F><A><P><T><D><T><S><D><M><E><A><V><W><K><E><A><K><P><E><D><L><M><D><S><K><L><R><C><V><F><E><L><P><A><E><N><D><K><P><H><D><V><E><I><N><K><I><I><S><T><T><A><S><K><T><E><T><P><I><V><S><K><S><L><S><S><S><L><D><D><T><E><V><K><K><V><M><E><E><C><K><R><L><Q><G><E><V><Q><R><L><R><E><E><N><K><Q><F><K><E><E><D><G><L><R><M><R><K><T><V><Q><S><N><S><P><I><S><A><L><A><P><T><G><K><E><E><G><L><S><T><R><L><L><A><L><V><V><L><F><F><I><V><G><V><I><I><G><K><I><A><L>	Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<BOP>	O95292
Q9H467	CUED2_HUMAN	CUE domain-containing protein 2	Homo	<M><E><L><E><R><I><V><S><A><A><L><L><A><F><V><Q><T><H><L><P><E><A><D><L><S><G><L><D><E><V><I><F><S><Y><V><L><G><V><L><E><D><L><G><P><S><G><P><S><E><E><N><F><D><M><E><A><F><T><E><M><M><E><A><Y><V><P><G><F><A><H><I><P><R><G><T><I><G><D><M><M><Q><K><L><S><G><Q><L><S><D><A><R><N><K><E><N><L><Q><P><Q><S><S><G><V><Q><G><Q><V><P><I><S><P><E><P><L><Q><R><P><E><M><L><K><E><E><T><R><S><S><A><A><A><A><A><D><T><Q><D><E><A><T><G><A><E><E><E><L><L><P><G><V><D><V><L><L><E><V><F><P><T><C><S><V><E><Q><A><Q><W><V><L><A><K><A><R><G><D><L><E><E><A><V><Q><M><L><V><E><G><K><E><E><G><P><A><A><W><E><G><P><N><Q><D><L><P><R><R><L><R><G><P><Q><K><D><E><L><K><S><F><I><L><Q><K><Y><M><M><V><D><S><A><E><D><Q><K><I><H><R><P><M><A><P><K><E><A><P><K><K><L><I><R><Y><I><D><N><Q><V><V><S><T><K><G><E><R><F><K><D><V><R><N><P><E><A><E><E><M><K><A><T><Y><I><N><L><K><P><A><R><K><Y><R><F><H>	Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.<BOP>	Q9H467
Q9Y6Z7	COL10_HUMAN	Collectin-34	Homo	<M><N><G><F><A><S><L><L><R><R><N><Q><F><I><L><L><V><L><F><L><L><Q><I><Q><S><L><G><L><D><I><D><S><R><P><T><A><E><V><C><A><T><H><T><I><S><P><G><P><K><G><D><D><G><E><K><G><D><P><G><E><E><G><K><H><G><K><V><G><R><M><G><P><K><G><I><K><G><E><L><G><D><M><G><D><Q><G><N><I><G><K><T><G><P><I><G><K><K><G><D><K><G><E><K><G><L><L><G><I><P><G><E><K><G><K><A><G><T><V><C><D><C><G><R><Y><R><K><F><V><G><Q><L><D><I><S><I><A><R><L><K><T><S><M><K><F><V><K><N><V><I><A><G><I><R><E><T><E><E><K><F><Y><Y><I><V><Q><E><E><K><N><Y><R><E><S><L><T><H><C><R><I><R><G><G><M><L><A><M><P><K><D><E><A><A><N><T><L><I><A><D><Y><V><A><K><S><G><F><F><R><V><F><I><G><V><N><D><L><E><R><E><G><Q><Y><M><F><T><D><N><T><P><L><Q><N><Y><S><N><W><N><E><G><E><P><S><D><P><Y><G><H><E><D><C><V><E><M><L><S><S><G><R><W><N><D><T><E><C><H><L><T><M><Y><F><V><C><E><F><I><K><K><K><K>	Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine . Acts as a chemoattractant, probably involved in the regulation of cell migration .<BOP>	Q9Y6Z7
Q30KR1	DB109_HUMAN	Defensin, beta 109B	Homo	<M><R><L><H><L><L><L><L><I><L><L><L><F><S><I><L><L><S><P><V><R><G><G><L><G><P><A><E><G><H><C><L><N><L><F><G><V><C><R><T><D><V><C><N><I><V><E><D><Q><I><G><A><C><R><R><R><M><K><C><C><R><A><W><W><I><L><M><P><I><P><T><P><L><I><M><S><D><Y><Q><E><P><L><K><P><N><L><K>	Has antibacterial activity.<BOP>	Q30KR1
A0A0C4DH39	HV158_HUMAN	Immunoglobulin heavy variable 1-58	Homo	<M><D><W><I><W><R><I><L><F><L><V><G><A><A><T><G><A><H><S><Q><M><Q><L><V><Q><S><G><P><E><V><K><K><P><G><T><S><V><K><V><S><C><K><A><S><G><F><T><F><T><S><S><A><V><Q><W><V><R><Q><A><R><G><Q><R><L><E><W><I><G><W><I><V><V><G><S><G><N><T><N><Y><A><Q><K><F><Q><E><R><V><T><I><T><R><D><M><S><T><S><T><A><Y><M><E><L><S><S><L><R><S><E><D><T><A><V><Y><Y><C><A><A>	V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen .<BOP>	A0A0C4DH39
P51523	ZNF84_HUMAN	Zinc finger protein HPF2	Homo	<M><T><M><L><Q><E><S><F><S><F><D><D><L><S><V><D><F><T><Q><K><E><W><Q><L><L><D><P><S><Q><K><N><L><Y><K><D><V><M><L><E><N><Y><S><S><L><V><S><L><G><Y><E><V><M><K><P><D><V><I><F><K><L><E><Q><G><E><E><P><W><V><G><D><G><E><I><P><S><S><D><S><P><E><V><W><K><V><D><G><N><M><M><W><H><Q><D><N><Q><D><K><L><K><I><I><K><R><G><H><E><C><D><A><F><G><K><N><F><N><L><N><M><N><F><V><P><L><R><K><S><N><S><E><G><D><L><D><G><L><I><L><K><H><H><L><D><L><L><I><P><K><G><D><Y><G><K><A><E><S><D><D><F><N><V><F><D><N><F><F><L><H><S><K><P><E><D><T><D><T><W><L><K><Y><Y><D><C><D><K><Y><K><E><S><Y><K><K><S><Q><I><I><I><Y><H><R><N><R><L><G><E><K><L><Y><E><C><S><E><C><R><K><R><F><S><K><K><P><S><L><I><K><H><Q><S><R><H><I><R><D><I><A><F><G><C><G><N><C><G><K><T><F><P><Q><K><S><Q><F><I><T><H><H><R><T><H><T><G><E><K><P><Y><N><C><S><Q><C><G><K><A><F><S><Q><K><S><Q><L><T><S><H><Q><R><T><H><T><G><E><K><P><Y><E><C><G><E><C><G><K><A><F><S><R><K><S><H><L><I><S><H><W><R><T><H><T><G><E><K><P><Y><G><C><N><E><C><G><R><A><F><S><E><K><S><N><L><I><N><H><Q><R><I><H><T><G><E><K><P><F><E><C><R><E><C><G><K><A><F><S><R><K><S><Q><L><V><T><H><H><R><T><H><T><G><T><K><P><F><G><C><S><D><C><R><K><A><F><F><E><K><S><E><L><I><R><H><Q><T><I><H><T><G><E><K><P><Y><E><C><S><E><C><R><K><A><F><R><E><R><S><S><L><I><N><H><Q><R><T><H><T><G><E><K><P><H><G><C><I><Q><C><G><K><A><F><S><Q><K><S><H><L><I><S><H><Q><M><T><H><T><G><E><K><P><F><I><C><S><K><C><G><K><A><F><S><R><K><S><Q><L><V><R><H><Q><R><T><H><T><G><E><K><P><Y><E><C><S><E><C><G><K><A><F><S><E><K><L><S><L><T><N><H><Q><R><I><H><T><G><E><K><P><Y><V><C><S><E><C><G><K><A><F><C><Q><K><S><H><L><I><S><H><Q><R><T><H><T><G><E><K><P><Y><E><C><S><E><C><G><K><A><F><G><E><K><S><S><L><A><T><H><Q><R><T><H><T><G><E><K><P><Y><E><C><R><D><C><E><K><A><F><S><Q><K><S><Q><L><N><T><H><Q><R><I><H><T><G><E><K><P><Y><E><C><S><L><C><R><K><A><F><F><E><K><S><E><L><I><R><H><L><R><T><H><T><G><E><K><P><Y><E><C><N><E><C><R><K><A><F><R><E><K><S><S><L><I><N><H><Q><R><I><H><T><G><E><K><P><F><E><C><S><E><C><G><K><A><F><S><R><K><S><H><L><I><P><H><Q><R><T><H><T><G><E><K><P><Y><G><C><S><E><C><R><K><A><F><S><Q><K><S><Q><L><V><N><H><Q><R><I><H><T><G><E><K><P><Y><R><C><I><E><C><G><K><A><F><S><Q><K><S><Q><L><I><N><H><Q><R><T><H><T><V><K><K><S>	May be involved in transcriptional regulation.<BOP>	P51523
P69905	HBA_HUMAN	Hemopressin	Homo	<M><V><L><S><P><A><D><K><T><N><V><K><A><A><W><G><K><V><G><A><H><A><G><E><Y><G><A><E><A><L><E><R><M><F><L><S><F><P><T><T><K><T><Y><F><P><H><F><D><L><S><H><G><S><A><Q><V><K><G><H><G><K><K><V><A><D><A><L><T><N><A><V><A><H><V><D><D><M><P><N><A><L><S><A><L><S><D><L><H><A><H><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L><V><T><L><A><A><H><L><P><A><E><F><T><P><A><V><H><A><S><L><D><K><F><L><A><S><V><S><T><V><L><T><S><K><Y><R>	Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 . Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling .<BOP>	P69905
A0A0B4J1X8	HV343_HUMAN	Immunoglobulin heavy variable 3-43	Homo	<M><E><F><G><L><S><W><V><F><L><V><A><I><L><K><G><V><Q><C><E><V><Q><L><V><E><S><G><G><V><V><V><Q><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><D><D><Y><T><M><H><W><V><R><Q><A><P><G><K><G><L><E><W><V><S><L><I><S><W><D><G><G><S><T><Y><Y><A><D><S><V><K><G><R><F><T><I><S><R><D><N><S><K><N><S><L><Y><L><Q><M><N><S><L><R><T><E><D><T><A><L><Y><Y><C><A><K><D>	V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen .<BOP>	A0A0B4J1X8
P33908	MA1A1_HUMAN	Processing alpha-1,2-mannosidase IA	Homo	<M><P><V><G><G><L><L><P><L><F><S><S><P><A><G><G><V><L><G><G><G><L><G><G><G><G><G><R><K><G><S><G><P><A><A><L><R><L><T><E><K><F><V><L><L><L><V><F><S><A><F><I><T><L><C><F><G><A><I><F><F><L><P><D><S><S><K><L><L><S><G><V><L><F><H><S><S><P><A><L><Q><P><A><A><D><H><K><P><G><P><G><A><R><A><E><D><A><A><E><G><R><A><R><R><R><E><E><G><A><P><G><D><P><E><A><A><L><E><D><N><L><A><R><I><R><E><N><H><E><R><A><L><R><E><A><K><E><T><L><Q><K><L><P><E><E><I><Q><R><D><I><L><L><E><K><K><K><V><A><Q><D><Q><L><R><D><K><A><P><F><R><G><L><P><P><V><D><F><V><P><P><I><G><V><E><S><R><E><P><A><D><A><A><I><R><E><K><R><A><K><I><K><E><M><M><K><H><A><W><N><N><Y><K><G><Y><A><W><G><L><N><E><L><K><P><I><S><K><G><G><H><S><S><S><L><F><G><N><I><K><G><A><T><I><V><D><A><L><D><T><L><F><I><M><E><M><K><H><E><F><E><E><A><K><S><W><V><E><E><N><L><D><F><N><V><N><A><E><I><S><V><F><E><V><N><I><R><F><V><G><G><L><L><S><A><Y><Y><L><S><G><E><E><I><F><R><K><K><A><V><E><L><G><V><K><L><L><P><A><F><H><T><P><S><G><I><P><W><A><L><L><N><M><K><S><G><I><G><R><N><W><P><W><A><S><G><G><S><S><I><L><A><E><F><G><T><L><H><L><E><F><M><H><L><S><H><L><S><G><N><P><I><F><A><E><K><V><M><N><I><R><T><V><L><N><K><L><E><K><P><Q><G><L><Y><P><N><Y><L><N><P><S><S><G><Q><W><G><Q><H><H><V><S><V><G><G><L><G><D><S><F><Y><E><Y><L><L><K><A><W><L><M><S><D><K><T><D><L><E><A><K><K><M><Y><F><D><A><V><Q><A><I><E><T><H><L><I><R><K><S><S><S><G><L><T><Y><I><A><E><W><K><G><G><L><L><E><H><K><M><G><H><L><T><C><F><A><G><G><M><F><A><L><G><A><D><A><A><P><E><G><M><A><Q><H><Y><L><E><L><G><A><E><I><A><R><T><C><H><E><S><Y><N><R><T><F><M><K><L><G><P><E><A><F><R><F><D><G><G><V><E><A><I><A><T><R><Q><N><E><K><Y><Y><I><L><R><P><E><V><M><E><T><Y><M><Y><M><W><R><L><T><H><D><P><K><Y><R><K><W><A><W><E><A><V><E><A><L><E><N><H><C><R><V><N><G><G><Y><S><G><L><R><D><V><Y><L><L><H><E><S><Y><D><D><V><Q><Q><S><F><F><L><A><E><T><L><K><Y><L><Y><L><I><F><S><D><D><D><L><L><P><L><E><H><W><I><F><N><S><E><A><H><L><L><P><I><L><P><K><D><K><K><E><V><E><I><R><E><E>	Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).<BOP>	P33908
P26992	CNTFR_HUMAN	Ciliary neurotrophic factor receptor subunit alpha	Homo	<M><A><A><P><V><P><W><A><C><C><A><V><L><A><A><A><A><A><V><V><Y><A><Q><R><H><S><P><Q><E><A><P><H><V><Q><Y><E><R><L><G><S><D><V><T><L><P><C><G><T><A><N><W><D><A><A><V><T><W><R><V><N><G><T><D><L><A><P><D><L><L><N><G><S><Q><L><V><L><H><G><L><E><L><G><H><S><G><L><Y><A><C><F><H><R><D><S><W><H><L><R><H><Q><V><L><L><H><V><G><L><P><P><R><E><P><V><L><S><C><R><S><N><T><Y><P><K><G><F><Y><C><S><W><H><L><P><T><P><T><Y><I><P><N><T><F><N><V><T><V><L><H><G><S><K><I><M><V><C><E><K><D><P><A><L><K><N><R><C><H><I><R><Y><M><H><L><F><S><T><I><K><Y><K><V><S><I><S><V><S><N><A><L><G><H><N><A><T><A><I><T><F><D><E><F><T><I><V><K><P><D><P><P><E><N><V><V><A><R><P><V><P><S><N><P><R><R><L><E><V><T><W><Q><T><P><S><T><W><P><D><P><E><S><F><P><L><K><F><F><L><R><Y><R><P><L><I><L><D><Q><W><Q><H><V><E><L><S><D><G><T><A><H><T><I><T><D><A><Y><A><G><K><E><Y><I><I><Q><V><A><A><K><D><N><E><I><G><T><W><S><D><W><S><V><A><A><H><A><T><P><W><T><E><E><P><R><H><L><T><T><E><A><Q><A><A><E><T><T><T><S><T><T><S><S><L><A><P><P><P><T><T><K><I><C><D><P><G><E><L><G><S><G><G><G><P><S><A><P><F><L><V><S><V><P><I><T><L><A><L><A><A><A><A><A><T><A><S><S><L><L><I>	Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1 . Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1 .<BOP>	P26992
A0A5A6	TVBK3_HUMAN	T cell receptor beta variable 11-3	Homo	<M><G><T><R><L><L><C><W><V><A><F><C><L><L><V><E><E><L><I><E><A><G><V><V><Q><S><P><R><Y><K><I><I><E><K><K><Q><P><V><A><F><W><C><N><P><I><S><G><H><N><T><L><Y><W><Y><L><Q><N><L><G><Q><G><P><E><L><L><I><R><Y><E><N><E><E><A><V><D><D><S><Q><L><P><K><D><R><F><S><A><E><R><L><K><G><V><D><S><T><L><K><I><Q><P><A><E><L><G><D><S><A><V><Y><L><C><A><S><S><L>	V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens . Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation . The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement	A0A5A6
O96017	CHK2_HUMAN	Checkpoint kinase 2	Homo	<M><S><R><E><S><D><V><E><A><Q><Q><S><H><G><S><S><A><C><S><Q><P><H><G><S><V><T><Q><S><Q><G><S><S><S><Q><S><Q><G><I><S><S><S><S><T><S><T><M><P><N><S><S><Q><S><S><H><S><S><S><G><T><L><S><S><L><E><T><V><S><T><Q><E><L><Y><S><I><P><E><D><Q><E><P><E><D><Q><E><P><E><E><P><T><P><A><P><W><A><R><L><W><A><L><Q><D><G><F><A><N><L><E><C><V><N><D><N><Y><W><F><G><R><D><K><S><C><E><Y><C><F><D><E><P><L><L><K><R><T><D><K><Y><R><T><Y><S><K><K><H><F><R><I><F><R><E><V><G><P><K><N><S><Y><I><A><Y><I><E><D><H><S><G><N><G><T><F><V><N><T><E><L><V><G><K><G><K><R><R><P><L><N><N><N><S><E><I><A><L><S><L><S><R><N><K><V><F><V><F><F><D><L><T><V><D><D><Q><S><V><Y><P><K><A><L><R><D><E><Y><I><M><S><K><T><L><G><S><G><A><C><G><E><V><K><L><A><F><E><R><K><T><C><K><K><V><A><I><K><I><I><S><K><R><K><F><A><I><G><S><A><R><E><A><D><P><A><L><N><V><E><T><E><I><E><I><L><K><K><L><N><H><P><C><I><I><K><I><K><N><F><F><D><A><E><D><Y><Y><I><V><L><E><L><M><E><G><G><E><L><F><D><K><V><V><G><N><K><R><L><K><E><A><T><C><K><L><Y><F><Y><Q><M><L><L><A><V><Q><Y><L><H><E><N><G><I><I><H><R><D><L><K><P><E><N><V><L><L><S><S><Q><E><E><D><C><L><I><K><I><T><D><F><G><H><S><K><I><L><G><E><T><S><L><M><R><T><L><C><G><T><P><T><Y><L><A><P><E><V><L><V><S><V><G><T><A><G><Y><N><R><A><V><D><C><W><S><L><G><V><I><L><F><I><C><L><S><G><Y><P><P><F><S><E><H><R><T><Q><V><S><L><K><D><Q><I><T><S><G><K><Y><N><F><I><P><E><V><W><A><E><V><S><E><K><A><L><D><L><V><K><K><L><L><V><V><D><P><K><A><R><F><T><T><E><E><A><L><R><H><P><W><L><Q><D><E><D><M><K><R><K><F><Q><D><L><L><S><E><E><N><E><S><T><A><L><P><Q><V><L><A><Q><P><S><T><S><R><K><R><P><R><E><G><E><A><E><G><A><E><T><T><K><R><P><A><V><C><A><A><V><L>	(Microbial infection) Phosphorylates herpes simplex virus 1/HHV-1 protein ICP0 and thus activates its SUMO-targeted ubiquitin ligase activity.<BOP>	O96017
Q9H2I8	LRMDA_HUMAN	Leucine-rich melanocyte differentiation-associated protein	Homo	<M><E><K><Y><L><S><L><S><G><N><H><S><S><N><K><R><S><L><E><G><L><S><A><F><R><S><L><E><E><L><I><L><D><N><N><Q><L><G><D><D><L><V><L><P><G><L><P><R><L><H><T><L><T><L><N><K><N><R><I><T><D><L><E><N><L><L><D><H><L><A><E><V><T><P><A><L><E><Y><L><S><L><L><G><N><V><A><C><P><N><E><L><V><S><L><E><K><D><E><E><D><Y><K><R><Y><R><C><F><V><L><Y><K><L><P><N><L><K><F><L><D><A><Q><K><V><T><R><Q><E><R><E><E><A><L><V><R><G><V><F><M><K><V><V><K><P><K><A><S><S><E><D><V><A><S><S><P><E><R><H><Y><T><P><L><P><S><A><S><R><E><L><T><S><H><Q><G><V><L><G><K><C><R><Y><V><Y><Y><G><K><N><S><E><G><N><R><F><I><R><D><D><Q><L>	Required for melanocyte differentiation.<BOP>	Q9H2I8
Q8NBR0	P5I13_HUMAN	Damage-stimulated cytoplasmic protein 1	Homo	<M><A><P><P><P><P><S><P><Q><L><L><L><L><A><A><L><A><R><L><L><G><P><S><E><V><M><A><G><P><A><E><E><A><G><A><H><C><P><E><S><L><W><P><L><P><P><Q><V><S><P><R><V><T><Y><T><R><V><S><P><G><Q><A><E><D><V><T><F><L><Y><H><P><C><A><H><P><W><L><K><L><Q><L><A><L><L><A><Y><A><C><M><A><N><P><S><L><T><P><D><F><S><L><T><Q><D><R><P><L><V><L><T><A><W><G><L><A><L><E><M><A><W><V><E><P><A><W><A><A><H><W><L><M><R><R><R><R><R><K><Q><R><K><K><K><A><W><I><Y><C><E><S><L><S><G><P><A><P><S><E><P><T><P><G><R><G><R><L><C><R><R><G><C><V><Q><A><L><A><L><A><F><A><L><R><S><W><R><P><P><G><T><E><V><T><S><Q><G><P><R><Q><P><S><S><S><G><A><K><R><R><R><L><R><A><A><L><G><P><Q><P><T><R><S><A><L><R><F><P><S><A><S><P><G><S><L><K><A><K><Q><S><M><A><G><I><P><G><R><E><S><N><A><P><S><V><P><T><V><S><L><L><P><G><A><P><G><G><N><A><S><S><R><T><E><A><Q><V><P><N><G><Q><G><S><P><G><G><C><V><C><S><S><Q><A><S><P><A><P><R><A><A><A><P><P><R><A><A><R><G><P><T><P><R><T><E><E><A><A><W><A><A><M><A><L><T><F><L><L><V><L><L><T><L><A><T><L><C><T><R><L><H><R><N><F><R><R><G><E><S><I><Y><W><G><P><T><A><D><S><Q><D><T><V><A><A><V><L><K><R><R><L><L><Q><P><S><R><R><V><K><R><S><R><R><R><P><L><L><P><P><T><P><D><S><G><P><E><G><E><S><S><E>	May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed.<BOP>	Q8NBR0
P52429	DGKE_HUMAN	Diglyceride kinase epsilon	Homo	<M><E><A><E><R><R><P><A><P><G><S><P><S><E><G><L><F><A><D><G><H><L><I><L><W><T><L><C><S><V><L><L><P><V><F><I><T><F><W><C><S><L><Q><R><S><R><R><Q><L><H><R><R><D><I><F><R><K><S><K><H><G><W><R><D><T><D><L><F><S><Q><P><T><Y><C><C><V><C><A><Q><H><I><L><Q><G><A><F><C><D><C><C><G><L><R><V><D><E><G><C><L><R><K><A><D><K><R><F><Q><C><K><E><I><M><L><K><N><D><T><K><V><L><D><A><M><P><H><H><W><I><R><G><N><V><P><L><C><S><Y><C><M><V><C><K><Q><Q><C><G><C><Q><P><K><L><C><D><Y><R><C><I><W><C><Q><K><T><V><H><D><E><C><M><K><N><S><L><K><N><E><K><C><D><F><G><E><F><K><N><L><I><I><P><P><S><Y><L><T><S><I><N><Q><M><R><K><D><K><K><T><D><Y><E><V><L><A><S><K><L><G><K><Q><W><T><P><L><I><I><L><A><N><S><R><S><G><T><N><M><G><E><G><L><L><G><E><F><R><I><L><L><N><P><V><Q><V><F><D><V><T><K><T><P><P><I><K><A><L><Q><L><C><T><L><L><P><Y><Y><S><A><R><V><L><V><C><G><G><D><G><T><V><G><W><V><L><D><A><V><D><D><M><K><I><K><G><Q><E><K><Y><I><P><Q><V><A><V><L><P><L><G><T><G><N><D><L><S><N><T><L><G><W><G><T><G><Y><A><G><E><I><P><V><A><Q><V><L><R><N><V><M><E><A><D><G><I><K><L><D><R><W><K><V><Q><V><T><N><K><G><Y><Y><N><L><R><K><P><K><E><F><T><M><N><N><Y><F><S><V><G><P><D><A><L><M><A><L><N><F><H><A><H><R><E><K><A><P><S><L><F><S><S><R><I><L><N><K><A><V><Y><L><F><Y><G><T><K><D><C><L><V><Q><E><C><K><D><L><N><K><K><V><E><L><E><L><D><G><E><R><V><A><L><P><S><L><E><G><I><I><V><L><N><I><G><Y><W><G><G><G><C><R><L><W><E><G><M><G><D><E><T><Y><P><L><A><R><H><D><D><G><L><L><E><V><V><G><V><Y><G><S><F><H><C><A><Q><I><Q><V><K><L><A><N><P><F><R><I><G><Q><A><H><T><V><R><L><I><L><K><C><S><M><M><P><M><Q><V><D><G><E><P><W><A><Q><G><P><C><T><V><T><I><T><H><K><T><H><A><M><M><L><Y><F><S><G><E><Q><T><D><D><D><I><S><S><T><S><D><Q><E><D><I><K><A><T><E>	Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes . Also plays an important role in the biosynthesis of complex lipids . Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle . Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently .<BOP>	P52429
A6NHG9	O5H14_HUMAN	Olfactory receptor 5H14	Homo	<M><E><E><E><N><A><T><L><L><T><E><F><V><L><T><G><F><L><Y><Q><P><Q><W><K><I><P><L><F><L><A><F><L><V><I><Y><L><I><T><I><M><G><N><L><G><L><I><A><V><I><W><K><D><P><H><L><H><I><P><M><Y><L><L><L><G><N><L><A><F><V><D><A><L><L><S><S><S><V><T><L><K><M><L><I><N><F><L><A><K><S><K><M><I><S><L><S><E><C><K><I><Q><L><F><S><F><A><I><S><V><T><T><E><C><F><L><L><A><T><M><A><Y><D><R><Y><V><A><I><C><K><P><L><L><Y><P><A><I><M><T><N><G><L><C><I><R><L><L><I><L><S><Y><V><G><G><L><L><H><A><L><I><H><E><G><F><L><F><R><L><T><F><C><N><S><N><I><I><Q><H><F><Y><C><D><I><I><P><L><L><K><I><S><Y><T><D><S><S><I><N><F><L><M><V><F><I><F><A><G><S><I><Q><V><F><T><I><G><T><V><L><I><S><Y><I><F><V><L><Y><T><I><L><K><K><K><S><V><K><G><M><R><K><A><F><S><T><C><G><A><H><L><L><S><V><S><L><Y><Y><G><P><L><A><F><M><Y><M><G><S><A><S><P><Q><A><D><D><Q><D><M><M><E><S><L><F><Y><T><V><I><V><P><L><L><N><P><M><I><Y><S><L><R><N><K><Q><V><I><A><S><F><T><K><M><F><K><R><N><D><V>	Odorant receptor.<BOP>	A6NHG9
Q96PM9	Z385A_HUMAN	Retinal zinc finger protein	Homo	<M><I><L><G><S><L><S><R><A><G><P><L><P><L><L><R><Q><P><P><I><M><Q><P><P><L><D><L><K><Q><I><L><P><F><P><L><E><P><A><P><T><L><G><L><F><S><N><Y><S><T><M><D><P><V><Q><K><A><V><L><S><H><T><F><G><G><P><L><L><K><T><K><R><P><V><I><S><C><N><I><C><Q><I><R><F><N><S><Q><S><Q><A><E><A><H><Y><K><G><N><R><H><A><R><R><V><K><G><I><E><A><A><K><T><R><G><R><E><P><G><V><R><E><P><G><D><P><A><P><P><G><S><T><P><T><N><G><D><G><V><A><P><R><P><V><S><M><E><N><G><L><G><P><A><P><G><S><P><E><K><Q><P><G><S><P><S><P><P><S><I><P><E><T><G><Q><G><V><T><K><G><E><G><G><T><P><A><P><A><S><L><P><G><G><S><K><E><E><E><E><K><A><K><R><L><L><Y><C><A><L><C><K><V><A><V><N><S><L><S><Q><L><E><A><H><N><K><G><T><K><H><K><T><I><L><E><A><R><S><G><L><G><P><I><K><A><Y><P><R><L><G><P><P><T><P><G><E><P><E><A><P><A><Q><D><R><T><F><H><C><E><I><C><N><V><K><V><N><S><E><V><Q><L><K><Q><H><I><S><S><R><R><H><R><D><G><V><A><G><K><P><N><P><L><L><S><R><H><K><K><S><R><G><A><G><E><L><A><G><T><L><T><F><S><K><E><L><P><K><S><L><A><G><G><L><L><P><S><P><L><A><V><A><A><V><M><A><A><A><A><G><S><P><L><S><L><R><P><A><P><A><A><P><L><L><Q><G><P><P><I><T><H><P><L><L><H><P><A><P><G><P><I><R><T><A><H><G><P><I><L><F><S><P><Y>	RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation.<BOP>	Q96PM9
P47871	GLR_HUMAN	Glucagon receptor	Homo	<M><P><P><C><Q><P><Q><R><P><L><L><L><L><L><L><L><L><A><C><Q><P><Q><V><P><S><A><Q><V><M><D><F><L><F><E><K><W><K><L><Y><G><D><Q><C><H><H><N><L><S><L><L><P><P><P><T><E><L><V><C><N><R><T><F><D><K><Y><S><C><W><P><D><T><P><A><N><T><T><A><N><I><S><C><P><W><Y><L><P><W><H><H><K><V><Q><H><R><F><V><F><K><R><C><G><P><D><G><Q><W><V><R><G><P><R><G><Q><P><W><R><D><A><S><Q><C><Q><M><D><G><E><E><I><E><V><Q><K><E><V><A><K><M><Y><S><S><F><Q><V><M><Y><T><V><G><Y><S><L><S><L><G><A><L><L><L><A><L><A><I><L><G><G><L><S><K><L><H><C><T><R><N><A><I><H><A><N><L><F><A><S><F><V><L><K><A><S><S><V><L><V><I><D><G><L><L><R><T><R><Y><S><Q><K><I><G><D><D><L><S><V><S><T><W><L><S><D><G><A><V><A><G><C><R><V><A><A><V><F><M><Q><Y><G><I><V><A><N><Y><C><W><L><L><V><E><G><L><Y><L><H><N><L><L><G><L><A><T><L><P><E><R><S><F><F><S><L><Y><L><G><I><G><W><G><A><P><M><L><F><V><V><P><W><A><V><V><K><C><L><F><E><N><V><Q><C><W><T><S><N><D><N><M><G><F><W><W><I><L><R><F><P><V><F><L><A><I><L><I><N><F><F><I><F><V><R><I><V><Q><L><L><V><A><K><L><R><A><R><Q><M><H><H><T><D><Y><K><F><R><L><A><K><S><T><L><T><L><I><P><L><L><G><V><H><E><V><V><F><A><F><V><T><D><E><H><A><Q><G><T><L><R><S><A><K><L><F><F><D><L><F><L><S><S><F><Q><G><L><L><V><A><V><L><Y><C><F><L><N><K><E><V><Q><S><E><L><R><R><R><W><H><R><W><R><L><G><K><V><L><W><E><E><R><N><T><S><N><H><R><A><S><S><S><P><G><H><G><P><P><S><K><E><L><Q><F><G><R><G><G><G><S><Q><D><S><S><A><E><T><P><L><A><G><G><L><P><R><L><A><E><S><P><F>	G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.<BOP>	P47871
Q9NVA4	T184C_HUMAN	Transmembrane protein 34	Homo	<M><P><C><T><C><T><W><R><N><W><R><Q><W><I><R><P><L><V><A><V><I><Y><L><V><S><I><V><V><A><V><P><L><C><V><W><E><L><Q><K><L><E><V><G><I><H><T><K><A><W><F><I><A><G><I><F><L><L><L><T><I><P><I><S><L><W><V><I><L><Q><H><L><V><H><Y><T><Q><P><E><L><Q><K><P><I><I><R><I><L><W><M><V><P><I><Y><S><L><D><S><W><I><A><L><K><Y><P><G><I><A><I><Y><V><D><T><C><R><E><C><Y><E><A><Y><V><I><Y><N><F><M><G><F><L><T><N><Y><L><T><N><R><Y><P><N><L><V><L><I><L><E><A><K><D><Q><Q><K><H><F><P><P><L><C><C><C><P><P><W><A><M><G><E><V><L><L><F><R><C><K><L><G><V><L><Q><Y><T><V><V><R><P><F><T><T><I><V><A><L><I><C><E><L><L><G><I><Y><D><E><G><N><F><S><F><S><N><A><W><T><Y><L><V><I><I><N><N><M><S><Q><L><F><A><M><Y><C><L><L><L><F><Y><K><V><L><K><E><E><L><S><P><I><Q><P><V><G><K><F><L><C><V><K><L><V><V><F><V><S><F><W><Q><A><V><V><I><A><L><L><V><K><V><G><V><I><S><E><K><H><T><W><E><W><Q><T><V><E><A><V><A><T><G><L><Q><D><F><I><I><C><I><E><M><F><L><A><A><I><A><H><H><Y><T><F><S><Y><K><P><Y><V><Q><E><A><E><E><G><S><C><F><D><S><F><L><A><M><W><D><V><S><D><I><R><D><D><I><S><E><Q><V><R><H><V><G><R><T><V><R><G><H><P><R><K><K><L><F><P><E><D><Q><D><Q><N><E><H><T><S><L><L><S><S><S><S><Q><D><A><I><S><I><A><S><S><M><P><P><S><P><M><G><H><Y><Q><G><F><G><H><T><V><T><P><Q><T><T><P><T><T><A><K><I><S><D><E><I><L><S><D><T><I><G><E><K><K><E><P><S><D><K><S><V><D><S>	Possible tumor suppressor which may play a role in cell growth.<BOP>	Q9NVA4
Q9H511	KLH31_HUMAN	Kelch-like protein KLHL	Homo	<M><A><P><K><K><K><I><V><K><K><N><K><G><D><I><N><E><M><T><I><I><V><E><D><S><P><L><N><K><L><N><A><L><N><G><L><L><E><G><G><N><G><L><S><C><I><S><S><E><L><T><D><A><S><Y><G><P><N><L><L><E><G><L><S><K><M><R><Q><E><N><F><L><C><D><L><V><I><G><T><K><T><K><S><F><D><V><H><K><S><V><M><A><S><C><S><E><Y><F><Y><N><I><L><K><K><D><P><S><I><Q><R><V><D><L><N><D><I><S><P><L><G><L><A><T><V><I><A><Y><A><Y><T><G><K><L><T><L><S><L><Y><T><I><G><S><I><I><S><A><A><V><Y><L><Q><I><H><T><L><V><K><M><C><S><D><F><L><I><R><E><M><S><V><E><N><C><M><Y><V><V><N><I><A><E><T><Y><S><L><K><N><A><K><A><A><A><Q><K><F><I><R><D><N><F><L><E><F><A><E><S><D><Q><F><M><K><L><T><F><E><Q><I><N><E><L><L><I><D><D><D><L><Q><L><P><S><E><I><V><A><F><Q><I><A><M><K><W><L><E><F><D><Q><K><R><V><K><Y><A><A><D><L><L><S><N><I><R><F><G><T><I><S><A><Q><D><L><V><N><Y><V><Q><S><V><P><R><M><M><Q><D><A><D><C><H><R><L><L><V><D><A><M><N><Y><H><L><L><P><Y><H><Q><N><T><L><Q><S><R><R><T><R><I><R><G><G><C><R><V><L><V><T><V><G><G><R><P><G><L><T><E><K><S><L><S><R><D><I><L><Y><R><D><P><E><N><G><W><S><K><L><T><E><M><P><A><K><S><F><N><Q><C><V><A><V><M><D><G><F><L><Y><V><A><G><G><E><D><Q><N><D><A><R><N><Q><A><K><H><A><V><S><N><F><C><R><Y><D><P><R><F><N><T><W><I><H><L><A><S><M><N><Q><K><R><T><H><F><S><L><S><V><F><N><G><L><V><Y><A><A><G><G><R><N><A><E><G><S><L><A><S><L><E><C><Y><V><P><S><T><N><Q><W><Q><P><K><T><P><L><E><V><A><R><C><C><H><A><S><A><V><A><D><G><R><V><L><V><T><G><G><Y><I><A><N><A><Y><S><R><S><V><C><A><Y><D><P><A><S><D><S><W><Q><E><L><P><N><L><S><T><P><R><G><W><H><C><A><V><T><L><S><D><R><V><Y><V><M><G><G><S><Q><L><G><P><R><G><E><R><V><D><V><L><T><V><E><C><Y><S><P><A><T><G><Q><W><S><Y><A><A><P><L><Q><V><G><V><S><T><A><G><V><S><A><L><H><G><R><A><Y><L><V><G><G><W><N><E><G><E><K><K><Y><K><K><C><I><Q><C><F><S><P><E><L><N><E><W><T><E><D><D><E><L><P><E><A><T><V><G><V><S><C><C><T><L><S><M><P><N><N><V><T><R><E><S><R><A><S><S><V><S><S><V><P><V><S><I>	Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).<BOP>	Q9H511
P01906	DQA2_HUMAN	MHC class II DQA2	Homo	<M><I><L><N><K><A><L><L><L><G><A><L><A><L><T><A><V><M><S><P><C><G><G><E><D><I><V><A><D><H><V><A><S><Y><G><V><N><F><Y><Q><S><H><G><P><S><G><Q><Y><T><H><E><F><D><G><D><E><E><F><Y><V><D><L><E><T><K><E><T><V><W><Q><L><P><M><F><S><K><F><I><S><F><D><P><Q><S><A><L><R><N><M><A><V><G><K><H><T><L><E><F><M><M><R><Q><S><N><S><T><A><A><T><N><E><V><P><E><V><T><V><F><S><K><F><P><V><T><L><G><Q><P><N><T><L><I><C><L><V><D><N><I><F><P><P><V><V><N><I><T><W><L><S><N><G><H><S><V><T><E><G><V><S><E><T><S><F><L><S><K><S><D><H><S><F><F><K><I><S><Y><L><T><F><L><P><S><A><D><E><I><Y><D><C><K><V><E><H><W><G><L><D><E><P><L><L><K><H><W><E><P><E><I><P><A><P><M><S><E><L><T><E><T><L><V><C><A><L><G><L><S><V><G><L><M><G><I><V><V><G><T><V><F><I><I><Q><G><L><R><S><V><G><A><S><R><H><Q><G><L><L>	Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To	P01906
A8MTA8	F166B_HUMAN	Protein FAM166B	Homo	<M><A><V><A><S><T><F><I><P><G><L><N><P><Q><N><P><H><Y><I><P><G><Y><T><G><H><C><P><L><L><R><F><S><V><G><Q><T><Y><G><Q><V><T><G><Q><L><L><R><G><P><P><G><L><A><W><P><P><V><H><R><T><L><L><P><P><I><R><P><P><R><S><P><E><V><P><R><E><S><L><P><V><R><R><G><Q><E><R><L><S><S><S><M><I><P><G><Y><T><G><F><V><P><R><A><Q><F><I><F><A><K><N><C><S><Q><V><W><A><E><A><L><S><D><F><T><H><L><H><E><K><Q><G><S><E><E><L><P><K><E><A><K><G><R><K><D><T><E><K><D><Q><V><P><E><P><E><G><Q><L><E><E><P><T><L><E><V><V><E><Q><A><S><P><Y><S><M><D><D><R><D><P><R><K><F><F><M><S><G><F><T><G><Y><V><P><C><A><R><F><L><F><G><S><S><F><P><V><L><T><N><Q><A><L><Q><E><F><G><Q><K><H><S><P><G><S><A><Q><D><P><K><H><L><P><P><L><P><R><T><Y><P><Q><N><L><G><L><L><P><N><Y><G><G><Y><V><P><G><Y><K><F><Q><F><G><H><T><F><G><H><L><T><H><D><A><L><G><L><S><T><F><Q><K><Q><L><L><A>	Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.<BOP>	A8MTA8
Q9NRK6	ABCBA_HUMAN	Mitochondrial ATP-binding cassette 2	Homo	<M><R><G><P><P><A><W><P><L><R><L><L><E><P><P><S><P><A><E><P><G><R><L><L><P><V><A><C><V><W><A><A><A><S><R><V><P><G><S><L><S><P><F><T><G><L><R><P><A><R><L><W><G><A><G><P><A><L><L><W><G><V><G><A><A><R><R><W><R><S><G><C><R><G><G><G><P><G><A><S><R><G><V><L><G><L><A><R><L><L><G><L><W><A><R><G><P><G><S><C><R><C><G><A><F><A><G><P><G><A><P><R><L><P><R><A><R><F><P><G><G><P><A><A><A><A><W><A><G><D><E><A><W><R><R><G><P><A><A><P><P><G><D><K><G><R><L><R><P><A><A><A><G><L><P><E><A><R><K><L><L><G><L><A><Y><P><E><R><R><R><L><A><A><A><V><G><F><L><T><M><S><S><V><I><S><M><S><A><P><F><F><L><G><K><I><I><D><V><I><Y><T><N><P><T><V><D><Y><S><D><N><L><T><R><L><C><L><G><L><S><A><V><F><L><C><G><A><A><A><N><A><I><R><V><Y><L><M><Q><T><S><G><Q><R><I><V><N><R><L><R><T><S><L><F><S><S><I><L><R><Q><E><V><A><F><F><D><K><T><R><T><G><E><L><I><N><R><L><S><S><D><T><A><L><L><G><R><S><V><T><E><N><L><S><D><G><L><R><A><G><A><Q><A><S><V><G><I><S><M><M><F><F><V><S><P><N><L><A><T><F><V><L><S><V><V><P><P><V><S><I><I><A><V><I><Y><G><R><Y><L><R><K><L><T><K><V><T><Q><D><S><L><A><Q><A><T><Q><L><A><E><E><R><I><G><N><V><R><T><V><R><A><F><G><K><E><M><T><E><I><E><K><Y><A><S><K><V><D><H><V><M><Q><L><A><R><K><E><A><F><A><R><A><G><F><F><G><A><T><G><L><S><G><N><L><I><V><L><S><V><L><Y><K><G><G><L><L><M><G><S><A><H><M><T><V><G><E><L><S><S><F><L><M><Y><A><F><W><V><G><I><S><I><G><G><L><S><S><F><Y><S><E><L><M><K><G><L><G><A><G><G><R><L><W><E><L><L><E><R><E><P><K><L><P><F><N><E><G><V><I><L><N><E><K><S><F><Q><G><A><L><E><F><K><N><V><H><F><A><Y><P><A><R><P><E><V><P><I><F><Q><D><F><S><L><S><I><P><S><G><S><V><T><A><L><V><G><P><S><G><S><G><K><S><T><V><L><S><L><L><L><R><L><Y><D><P><A><S><G><T><I><S><L><D><G><H><D><I><R><Q><L><N><P><V><W><L><R><S><K><I><G><T><V><S><Q><E><P><I><L><F><S><C><S><I><A><E><N><I><A><Y><G><A><D><D><P><S><S><V><T><A><E><E><I><Q><R><V><A><E><V><A><N><A><V><A><F><I><R><N><F><P><Q><G><F><N><T><V><V><G><E><K><G><V><L><L><S><G><G><Q><K><Q><R><I><A><I><A><R><A><L><L><K><N><P><K><I><L><L><L><D><E><A><T><S><A><L><D><A><E><N><E><Y><L><V><Q><E><A><L><D><R><L><M><D><G><R><T><V><L><V><I><A><H><R><L><S><T><I><K><N><A><N><M><V><A><V><L><D><Q><G><K><I><T><E><Y><G><K><H><E><E><L><L><S><K><P><N><G><I><Y><R><K><L><M><N><K><Q><S><F><I><S><A>	Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner . May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria . Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress . In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria .<BOP>	Q9NRK6
Q8WWI5	CTL1_HUMAN	Solute carrier family 44 member 1	Homo	<M><G><C><C><S><S><A><S><S><A><A><Q><S><S><K><R><E><W><K><P><L><E><D><R><S><C><T><D><I><P><W><L><L><L><F><I><L><F><C><I><G><M><G><F><I><C><G><F><S><I><A><T><G><A><A><A><R><L><V><S><G><Y><D><S><Y><G><N><I><C><G><Q><K><N><T><K><L><E><A><I><P><N><S><G><M><D><H><T><Q><R><K><Y><V><F><F><L><D><P><C><N><L><D><L><I><N><R><K><I><K><S><V><A><L><C><V><A><A><C><P><R><Q><E><L><K><T><L><S><D><V><Q><K><F><A><E><I><N><G><S><A><L><C><S><Y><N><L><K><P><S><E><Y><T><T><S><P><K><S><S><V><L><C><P><K><L><P><V><P><A><S><A><P><I><P><F><F><H><R><C><A><P><V><N><I><S><C><Y><A><K><F><A><E><A><L><I><T><F><V><S><D><N><S><V><L><H><R><L><I><S><G><V><M><T><S><K><E><I><I><L><G><L><C><L><L><S><L><V><L><S><M><I><L><M><V><I><I><R><Y><I><S><R><V><L><V><W><I><L><T><I><L><V><I><L><G><S><L><G><G><T><G><V><L><W><W><L><Y><A><K><Q><R><R><S><P><K><E><T><V><T><P><E><Q><L><Q><I><A><E><D><N><L><R><A><L><L><I><Y><A><I><S><A><T><V><F><T><V><I><L><F><L><I><M><L><V><M><R><K><R><V><A><L><T><I><A><L><F><H><V><A><G><K><V><F><I><H><L><P><L><L><V><F><Q><P><F><W><T><F><F><A><L><V><L><F><W><V><Y><W><I><M><T><L><L><F><L><G><T><T><G><S><P><V><Q><N><E><Q><G><F><V><E><F><K><I><S><G><P><L><Q><Y><M><W><W><Y><H><V><V><G><L><I><W><I><S><E><F><I><L><A><C><Q><Q><M><T><V><A><G><A><V><V><T><Y><Y><F><T><R><D><K><R><N><L><P><F><T><P><I><L><A><S><V><N><R><L><I><R><Y><H><L><G><T><V><A><K><G><S><F><I><I><T><L><V><K><I><P><R><M><I><L><M><Y><I><H><S><Q><L><K><G><K><E><N><A><C><A><R><C><V><L><K><S><C><I><C><C><L><W><C><L><E><K><C><L><N><Y><L><N><Q><N><A><Y><T><A><T><A><I><N><S><T><N><F><C><T><S><A><K><D><A><F><V><I><L><V><E><N><A><L><R><V><A><T><I><N><T><V><G><D><F><M><L><F><L><G><K><V><L><I><V><C><S><T><G><L><A><G><I><M><L><L><N><Y><Q><Q><D><Y><T><V><W><V><L><P><L><I><I><V><C><L><F><A><F><L><V><A><H><C><F><L><S><I><Y><E><M><V><V><D><V><L><F><L><C><F><A><I><D><T><K><Y><N><D><G><S><P><G><R><E><F><Y><M><D><K><V><L><M><E><F><V><E><N><S><R><K><A><M><K><E><A><G><K><G><G><V><A><D><S><R><E><L><K><P><M><A><S><G><A><S><S><A>	Choline transporter. Involved in membrane synthesis and myelin production.<BOP>	Q8WWI5
Q9NQE9	HINT3_HUMAN	Histidine triad nucleotide-binding protein 3	Homo	<M><A><E><E><Q><V><N><R><S><A><G><L><A><P><D><C><E><A><S><A><T><A><E><T><T><V><S><S><V><G><T><C><E><A><A><G><K><S><P><E><P><K><D><Y><D><S><T><C><V><F><C><R><I><A><G><R><Q><D><P><G><T><E><L><L><H><C><E><N><E><D><L><I><C><F><K><D><I><K><P><A><A><T><H><H><Y><L><V><V><P><K><K><H><I><G><N><C><R><T><L><R><K><D><Q><V><E><L><V><E><N><M><V><T><V><G><K><T><I><L><E><R><N><N><F><T><D><F><T><N><V><R><M><G><F><H><M><P><P><F><C><S><I><S><H><L><H><L><H><V><L><A><P><V><D><Q><L><G><F><L><S><K><L><V><Y><R><V><N><S><Y><W><F><I><T><A><D><H><L><I><E><K><L><R><T>	Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 . Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase . Hydrolyzes 3-indolepropionic acyl-adenylate and fluorogenic purine nucleoside tryptamine phosphoramidates in vitro .<BOP>	Q9NQE9
P31146	COR1A_HUMAN	Tryptophan aspartate-containing coat protein	Homo	<M><S><R><Q><V><V><R><S><S><K><F><R><H><V><F><G><Q><P><A><K><A><D><Q><C><Y><E><D><V><R><V><S><Q><T><T><W><D><S><G><F><C><A><V><N><P><K><F><V><A><L><I><C><E><A><S><G><G><G><A><F><L><V><L><P><L><G><K><T><G><R><V><D><K><N><A><P><T><V><C><G><H><T><A><P><V><L><D><I><A><W><C><P><H><N><D><N><V><I><A><S><G><S><E><D><C><T><V><M><V><W><E><I><P><D><G><G><L><M><L><P><L><R><E><P><V><V><T><L><E><G><H><T><K><R><V><G><I><V><A><W><H><T><T><A><Q><N><V><L><L><S><A><G><C><D><N><V><I><M><V><W><D><V><G><T><G><A><A><M><L><T><L><G><P><E><V><H><P><D><T><I><Y><S><V><D><W><S><R><D><G><G><L><I><C><T><S><C><R><D><K><R><V><R><I><I><E><P><R><K><G><T><V><V><A><E><K><D><R><P><H><E><G><T><R><P><V><R><A><V><F><V><S><E><G><K><I><L><T><T><G><F><S><R><M><S><E><R><Q><V><A><L><W><D><T><K><H><L><E><E><P><L><S><L><Q><E><L><D><T><S><S><G><V><L><L><P><F><F><D><P><D><T><N><I><V><Y><L><C><G><K><G><D><S><S><I><R><Y><F><E><I><T><S><E><A><P><F><L><H><Y><L><S><M><F><S><S><K><E><S><Q><R><G><M><G><Y><M><P><K><R><G><L><E><V><N><K><C><E><I><A><R><F><Y><K><L><H><E><R><R><C><E><P><I><A><M><T><V><P><R><K><S><D><L><F><Q><E><D><L><Y><P><P><T><A><G><P><D><P><A><L><T><A><E><E><W><L><G><G><R><D><A><G><P><L><L><I><S><L><K><D><G><Y><V><P><P><K><S><R><E><L><R><V><N><R><G><L><D><T><G><R><R><R><A><A><P><E><A><S><G><T><P><S><S><D><A><V><S><R><L><E><E><E><M><R><K><L><Q><A><T><V><Q><E><L><Q><K><R><L><D><R><L><E><E><T><V><Q><A><K>	May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.<BOP>	P31146
A0A286YF77	SCGR6_HUMAN	Keratin-associated protein 28-6	Homo	<M><G><C><C><G><C><G><G><C><G><G><G><C><G><G><C><G><G><G><C><S><G><G><C><G><G><G><C><G><G><G><C><G><S><C><T><T><C><R><C><Y><R><V><G><C><C><S><S><C><C><P><C><C><R><G><C><C><G><G><C><C><S><T><P><V><I><C><C><C><R><R><T><C><H><S><C><G><C><G><C><G><C><G><K><G><C><C><Q><Q><K><G><C><C><Q><Q><K><G><C><C><K><K><Q><C><C><C>	In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.<BOP>	A0A286YF77
O75312	ZPR1_HUMAN	Zinc finger protein 259	Homo	<M><A><A><S><G><A><V><E><P><G><P><P><G><A><A><V><A><P><S><P><A><P><A><P><P><P><A><P><D><H><L><F><R><P><I><S><A><E><D><E><E><Q><Q><P><T><E><I><E><S><L><C><M><N><C><Y><C><N><G><M><T><R><L><L><L><T><K><I><P><F><F><R><E><I><I><V><S><S><F><S><C><E><H><C><G><W><N><N><T><E><I><Q><S><A><G><R><I><Q><D><Q><G><V><R><Y><T><L><S><V><R><A><L><E><D><M><N><R><E><V><V><K><T><D><S><A><A><T><R><I><P><E><L><D><F><E><I><P><A><F><S><Q><K><G><A><L><T><T><V><E><G><L><I><T><R><A><I><S><G><L><E><Q><D><Q><P><A><R><R><A><N><K><D><A><T><A><E><R><I><D><E><F><I><V><K><L><K><E><L><K><Q><V><A><S><P><F><T><L><I><I><D><D><P><S><G><N><S><F><V><E><N><P><H><A><P><Q><K><D><D><A><L><V><I><T><H><Y><N><R><T><R><Q><Q><E><E><M><L><G><L><Q><E><E><A><P><A><E><K><P><E><E><E><D><L><R><N><E><V><L><Q><F><S><T><N><C><P><E><C><N><A><P><A><Q><T><N><M><K><L><V><Q><I><P><H><F><K><E><V><I><I><M><A><T><N><C><E><N><C><G><H><R><T><N><E><V><K><S><G><G><A><V><E><P><L><G><T><R><I><T><L><H><I><T><D><A><S><D><M><T><R><D><L><L><K><S><E><T><C><S><V><E><I><P><E><L><E><F><E><L><G><M><A><V><L><G><G><K><F><T><T><L><E><G><L><L><K><D><I><R><E><L><V><T><K><N><P><F><T><L><G><D><S><S><N><P><G><Q><T><E><R><L><Q><E><F><S><Q><K><M><D><Q><I><I><E><G><N><M><K><A><H><F><I><M><D><D><P><A><G><N><S><Y><L><Q><N><V><Y><A><P><E><D><D><P><E><M><K><V><E><R><Y><K><R><T><F><D><Q><N><E><E><L><G><L><N><D><M><K><T><E><G><Y><E><A><G><L><A><P><Q><R>	Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression . Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.<BOP>	O75312
Q5FVE4	ACBG2_HUMAN	PRTD-NY3	Homo	<M><T><G><T><P><K><T><Q><E><G><A><K><D><L><E><V><D><M><N><K><T><E><V><T><P><R><L><W><T><T><C><R><D><G><E><V><L><L><R><L><S><K><H><G><P><G><H><E><T><P><M><T><I><P><E><F><F><R><E><S><V><N><R><F><G><T><Y><P><A><L><A><S><K><N><G><K><K><W><E><I><L><N><F><N><Q><Y><Y><E><A><C><R><K><A><A><K><S><L><I><K><L><G><L><E><R><F><H><G><V><G><I><L><G><F><N><S><A><E><W><F><I><T><A><V><G><A><I><L><A><G><G><L><C><V><G><I><Y><A><T><N><S><A><E><V><C><Q><Y><V><I><T><H><A><K><V><N><I><L><L><V><E><N><D><Q><Q><L><Q><K><I><L><S><I><P><Q><S><S><L><E><P><L><K><A><I><I><Q><Y><R><L><P><M><K><K><N><N><N><L><Y><S><W><D><D><F><M><E><L><G><R><S><I><P><D><T><Q><L><E><Q><V><I><E><S><Q><K><A><N><Q><C><A><V><L><I><Y><T><S><G><T><T><G><I><P><K><G><V><M><L><S><H><D><N><I><T><W><I><A><G><A><V><T><K><D><F><K><L><T><D><K><H><E><T><V><V><S><Y><L><P><L><S><H><I><A><A><Q><M><M><D><I><W><V><P><I><K><I><G><A><L><T><Y><F><A><Q><A><D><A><L><K><G><T><L><V><S><T><L><K><E><V><K><P><T><V><F><I><G><V><P><Q><I><W><E><K><I><H><E><M><V><K><K><N><S><A><K><S><M><G><L><K><K><K><A><F><V><W><A><R><N><I><G><F><K><V><N><S><K><K><M><L><G><K><Y><N><T><P><V><S><Y><R><M><A><K><T><L><V><F><S><K><V><K><T><S><L><G><L><D><H><C><H><S><F><I><S><G><T><A><P><L><N><Q><E><T><A><E><F><F><L><S><L><D><I><P><I><G><E><L><Y><G><L><S><E><S><S><G><P><H><T><I><S><N><Q><N><N><Y><R><L><L><S><C><G><K><I><L><T><G><C><K><N><M><L><F><Q><Q><N><K><D><G><I><G><E><I><C><L><W><G><R><H><I><F><M><G><Y><L><E><S><E><T><E><T><T><E><A><I><D><D><E><G><W><L><H><S><G><D><L><G><Q><L><D><G><L><G><F><L><Y><V><T><G><H><I><K><E><I><L><I><T><A><G><G><E><N><V><P><P><I><P><V><E><T><L><V><K><K><K><I><P><I><I><S><N><A><M><L><V><G><D><K><L><K><F><L><S><M><L><L><T><L><K><C><E><M><N><Q><M><S><G><E><P><L><D><K><L><N><F><E><A><I><N><F><C><R><G><L><G><S><Q><A><S><T><V><T><E><I><V><K><Q><Q><D><P><L><V><Y><K><A><I><Q><Q><G><I><N><A><V><N><Q><E><A><M><N><N><A><Q><R><I><E><K><W><V><I><L><E><K><D><F><S><I><Y><G><G><E><L><G><P><M><M><K><L><K><R><H><F><V><A><Q><K><Y><K><K><Q><I><D><H><M><Y><H>	Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids . Has increased ability to activate oleic and linoleic acid . May play a role in spermatogenesis .<BOP>	Q5FVE4
P13861	KAP2_HUMAN	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo	<M><S><H><I><Q><I><P><P><G><L><T><E><L><L><Q><G><Y><T><V><E><V><L><R><Q><Q><P><P><D><L><V><E><F><A><V><E><Y><F><T><R><L><R><E><A><R><A><P><A><S><V><L><P><A><A><T><P><R><Q><S><L><G><H><P><P><P><E><P><G><P><D><R><V><A><D><A><K><G><D><S><E><S><E><E><D><E><D><L><E><V><P><V><P><S><R><F><N><R><R><V><S><V><C><A><E><T><Y><N><P><D><E><E><E><E><D><T><D><P><R><V><I><H><P><K><T><D><E><Q><R><C><R><L><Q><E><A><C><K><D><I><L><L><F><K><N><L><D><Q><E><Q><L><S><Q><V><L><D><A><M><F><E><R><I><V><K><A><D><E><H><V><I><D><Q><G><D><D><G><D><N><F><Y><V><I><E><R><G><T><Y><D><I><L><V><T><K><D><N><Q><T><R><S><V><G><Q><Y><D><N><R><G><S><F><G><E><L><A><L><M><Y><N><T><P><R><A><A><T><I><V><A><T><S><E><G><S><L><W><G><L><D><R><V><T><F><R><R><I><I><V><K><N><N><A><K><K><R><K><M><F><E><S><F><I><E><S><V><P><L><L><K><S><L><E><V><S><E><R><M><K><I><V><D><V><I><G><E><K><I><Y><K><D><G><E><R><I><I><T><Q><G><E><K><A><D><S><F><Y><I><I><E><S><G><E><V><S><I><L><I><R><S><R><T><K><S><N><K><D><G><G><N><Q><E><V><E><I><A><R><C><H><K><G><Q><Y><F><G><E><L><A><L><V><T><N><K><P><R><A><A><S><A><Y><A><V><G><D><V><K><C><L><V><M><D><V><Q><A><F><E><R><L><L><G><P><C><M><D><I><M><K><R><N><I><S><H><Y><E><E><Q><L><V><K><M><F><G><S><S><V><D><L><G><N><L><G><Q>	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.<BOP>	P13861
A0A0B4J249	TVA5_HUMAN	T cell receptor alpha variable 5	Homo	<M><K><T><F><A><G><F><S><F><L><F><L><W><L><Q><L><D><C><M><S><R><G><E><D><V><E><Q><S><L><F><L><S><V><R><E><G><D><S><S><V><I><N><C><T><Y><T><D><S><S><S><T><Y><L><Y><W><Y><K><Q><E><P><G><A><G><L><Q><L><L><T><Y><I><F><S><N><M><D><M><K><Q><D><Q><R><L><T><V><L><L><N><K><K><D><K><H><L><S><L><R><I><A><D><T><Q><T><G><D><S><A><I><Y><F><C><A><E><S>	V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens . Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation . The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement	A0A0B4J249
Q96JP0	FEM1C_HUMAN	FEM1-gamma	Homo	<M><D><L><K><T><A><V><F><N><A><A><R><D><G><K><L><R><L><L><T><K><L><L><A><S><K><S><K><E><E><V><S><S><L><I><S><E><K><T><N><G><A><T><P><L><L><M><A><A><R><Y><G><H><L><D><M><V><E><F><L><L><E><Q><C><S><A><S><I><E><V><G><G><S><V><N><F><D><G><E><T><I><E><G><A><P><P><L><W><A><A><S><A><A><G><H><L><K><V><V><Q><S><L><L><N><H><G><A><S><V><N><N><T><T><L><T><N><S><T><P><L><R><A><A><C><F><D><G><H><L><E><I><V><K><Y><L><V><E><H><K><A><D><L><E><V><S><N><R><H><G><H><T><C><L><M><I><S><C><Y><K><G><H><K><E><I><A><Q><Y><L><L><E><K><G><A><D><V><N><R><K><S><V><K><G><N><T><A><L><H><D><C><A><E><S><G><S><L><D><I><M><K><M><L><L><M><Y><C><A><K><M><E><K><D><G><Y><G><M><T><P><L><L><S><A><S><V><T><G><H><T><N><I><V><D><F><L><T><H><H><A><Q><T><S><K><T><E><R><I><N><A><L><E><L><L><G><A><T><F><V><D><K><K><R><D><L><L><G><A><L><K><Y><W><K><K><A><M><N><M><R><Y><S><D><R><T><N><I><I><S><K><P><V><P><Q><T><L><I><M><A><Y><D><Y><A><K><E><V><N><S><A><E><E><L><E><G><L><I><A><D><P><D><E><M><R><M><Q><A><L><L><I><R><E><R><I><L><G><P><S><H><P><D><T><S><Y><Y><I><R><Y><R><G><A><V><Y><A><D><S><G><N><F><K><R><C><I><N><L><W><K><Y><A><L><D><M><Q><Q><S><N><L><D><P><L><S><P><M><T><A><S><S><L><L><S><F><A><E><L><F><S><F><M><L><Q><D><R><A><K><G><L><L><G><T><T><V><T><F><D><D><L><M><G><I><L><C><K><S><V><L><E><I><E><R><A><I><K><Q><T><Q><C><P><A><D><P><L><Q><L><N><K><A><L><S><I><I><L><H><L><I><C><L><L><E><K><V><P><C><T><L><E><Q><D><H><F><K><K><Q><T><I><Y><R><F><L><K><L><H><P><R><G><K><N><N><F><S><P><L><H><L><A><V><D><K><N><T><T><C><V><G><R><Y><P><V><C><K><F><P><S><L><Q><V><T><A><I><L><I><E><C><G><A><D><V><N><V><R><D><S><D><D><N><S><P><L><H><I><A><A><L><N><N><H><P><D><I><M><N><L><L><I><K><S><G><A><H><F><D><A><T><N><L><H><K><Q><T><A><S><D><L><L><D><E><K><E><I><A><K><N><L><I><Q><P><I><N><H><T><T><L><Q><C><L><A><A><R><V><I><V><N><H><R><I><Y><Y><K><G><H><I><P><E><K><L><E><T><F><V><S><L><H><R>	Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation . The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms . The CRL2(FEM1C) complex specifically recognizes proteins with an arginine at the C-terminus: recognizes and binds proteins ending with -Lys/Arg-Xaa-Arg and -Lys/Arg-Xaa-Xaa-Arg C-degrons, such as SIL1 or OR51B2, leading to their ubiquitination and degradation . The CRL2(FEM1C) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding . Promotes ubiquitination and degradation of SLBP .<BOP>	Q96JP0
Q5VV42	CDKAL_HUMAN	tRNA-t(6)A37 methylthiotransferase	Homo	<M><P><S><A><S><C><D><T><L><L><D><D><I><E><D><I><V><S><Q><E><D><S><K><P><Q><D><R><H><F><V><R><K><D><V><V><P><K><V><R><R><R><N><T><Q><K><Y><L><Q><E><E><E><N><S><P><P><S><D><S><T><I><P><G><I><Q><K><I><W><I><R><T><W><G><C><S><H><N><N><S><D><G><E><Y><M><A><G><Q><L><A><A><Y><G><Y><K><I><T><E><N><A><S><D><A><D><L><W><L><L><N><S><C><T><V><K><N><P><A><E><D><H><F><R><N><S><I><K><K><A><Q><E><E><N><K><K><I><V><L><A><G><C><V><P><Q><A><Q><P><R><Q><D><Y><L><K><G><L><S><I><I><G><V><Q><Q><I><D><R><V><V><E><V><V><E><E><T><I><K><G><H><S><V><R><L><L><G><Q><K><K><D><N><G><R><R><L><G><G><A><R><L><D><L><P><K><I><R><K><N><P><L><I><E><I><I><S><I><N><T><G><C><L><N><A><C><T><Y><C><K><T><K><H><A><R><G><N><L><A><S><Y><P><I><D><E><L><V><D><R><A><K><Q><S><F><Q><E><G><V><C><E><I><W><L><T><S><E><D><T><G><A><Y><G><R><D><I><G><T><N><L><P><T><L><L><W><K><L><V><E><V><I><P><E><G><A><M><L><R><L><G><M><T><N><P><P><Y><I><L><E><H><L><E><E><M><A><K><I><L><N><H><P><R><V><Y><A><F><L><H><I><P><V><Q><S><A><S><D><S><V><L><M><E><M><K><R><E><Y><C><V><A><D><F><K><R><V><V><D><F><L><K><E><K><V><P><G><I><T><I><A><T><D><I><I><C><G><F><P><G><E><T><D><Q><D><F><Q><E><T><V><K><L><V><E><E><Y><K><F><P><S><L><F><I><N><Q><F><Y><P><R><P><G><T><P><A><A><K><M><E><Q><V><P><A><Q><V><K><K><Q><R><T><K><D><L><S><R><V><F><H><S><Y><S><P><Y><D><H><K><I><G><E><R><Q><Q><V><L><V><T><E><E><S><F><D><S><K><F><Y><V><A><H><N><Q><F><Y><E><Q><V><L><V><P><K><N><P><A><F><M><G><K><M><V><E><V><D><I><Y><E><S><G><K><H><F><M><K><G><Q><P><V><S><D><A><K><V><Y><T><P><S><I><S><K><P><L><A><K><G><E><V><S><G><L><T><K><D><F><R><N><G><L><G><N><Q><L><S><S><G><S><H><T><S><A><A><S><Q><C><D><S><A><S><S><R><M><V><L><P><M><P><R><L><H><Q><D><C><A><L><R><M><S><V><G><L><A><L><L><G><L><L><F><A><F><F><V><K><V><Y><N>	Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.<BOP>	Q5VV42
Q96AP7	ESAM_HUMAN	Endothelial cell-selective adhesion molecule	Homo	<M><I><S><L><P><G><P><L><V><T><N><L><L><R><F><L><F><L><G><L><S><A><L><A><P><P><S><R><A><Q><L><Q><L><H><L><P><A><N><R><L><Q><A><V><E><G><G><E><V><V><L><P><A><W><Y><T><L><H><G><E><V><S><S><S><Q><P><W><E><V><P><F><V><M><W><F><F><K><Q><K><E><K><E><D><Q><V><L><S><Y><I><N><G><V><T><T><S><K><P><G><V><S><L><V><Y><S><M><P><S><R><N><L><S><L><R><L><E><G><L><Q><E><K><D><S><G><P><Y><S><C><S><V><N><V><Q><D><K><Q><G><K><S><R><G><H><S><I><K><T><L><E><L><N><V><L><V><P><P><A><P><P><S><C><R><L><Q><G><V><P><H><V><G><A><N><V><T><L><S><C><Q><S><P><R><S><K><P><A><V><Q><Y><Q><W><D><R><Q><L><P><S><F><Q><T><F><F><A><P><A><L><D><V><I><R><G><S><L><S><L><T><N><L><S><S><S><M><A><G><V><Y><V><C><K><A><H><N><E><V><G><T><A><Q><C><N><V><T><L><E><V><S><T><G><P><G><A><A><V><V><A><G><A><V><V><G><T><L><V><G><L><G><L><L><A><G><L><V><L><L><Y><H><R><R><G><K><A><L><E><E><P><A><N><D><I><K><E><D><A><I><A><P><R><T><L><P><W><P><K><S><S><D><T><I><S><K><N><G><T><L><S><S><V><T><S><A><R><A><L><R><P><P><H><G><P><P><R><P><G><A><L><T><P><T><P><S><L><S><S><Q><A><L><P><S><P><R><L><P><T><T><D><G><A><H><P><Q><P><I><S><P><I><P><G><G><V><S><S><S><G><L><S><R><M><G><A><V><P><V><M><V><P><A><Q><S><Q><A><G><S><L><V>	Can mediate aggregation most likely through a homophilic molecular interaction.<BOP>	Q96AP7
Q8TBJ4	PLPR1_HUMAN	Plasticity-related gene 3 protein	Homo	<M><A><V><G><N><N><T><Q><R><S><Y><S><I><I><P><C><F><I><F><V><E><L><V><I><M><A><G><T><V><L><L><A><Y><Y><F><E><C><T><D><T><F><Q><V><H><I><Q><G><F><F><C><Q><D><G><D><L><M><K><P><Y><P><G><T><E><E><E><S><F><I><T><P><L><V><L><Y><C><V><L><A><A><T><P><T><A><I><I><F><I><G><E><I><S><M><Y><F><I><K><S><T><R><E><S><L><I><A><Q><E><K><T><I><L><T><G><E><C><C><Y><L><N><P><L><L><R><R><I><I><R><F><T><G><V><F><A><F><G><L><F><A><T><D><I><F><V><N><A><G><Q><V><V><T><G><H><L><T><P><Y><F><L><T><V><C><K><P><N><Y><T><S><A><D><C><Q><A><H><H><Q><F><I><N><N><G><N><I><C><T><G><D><L><E><V><I><E><K><A><R><R><S><F><P><S><K><H><A><A><L><S><I><Y><S><A><L><Y><A><T><M><Y><I><T><S><T><I><K><T><K><S><S><R><L><A><K><P><V><L><C><L><G><T><L><C><T><A><F><L><T><G><L><N><R><V><S><E><Y><R><N><H><C><S><D><V><I><A><G><F><I><L><G><T><A><V><A><L><F><L><G><M><C><V><V><H><N><F><K><G><T><Q><G><S><P><S><K><P><K><P><E><D><P><R><G><V><P><L><M><A><F><P><R><I><E><S><P><L><E><T><L><S><A><Q><N><H><S><A><S><M><T><E><V><T>	May play a role in neurite outgrowth and neurogenesis.<BOP>	Q8TBJ4
P57738	TCTA_HUMAN	T-cell leukemia translocation-associated gene protein	Homo	<M><A><E><S><W><S><G><Q><A><L><Q><A><L><P><A><T><V><L><G><A><L><G><S><E><F><L><R><E><W><E><A><Q><D><M><R><V><T><L><F><K><L><L><L><L><W><L><V><L><S><L><L><G><I><Q><L><A><W><G><F><Y><G><N><T><V><T><G><L><Y><H><R><P><G><L><G><G><Q><N><G><S><T><P><D><G><S><T><H><F><P><S><W><E><M><A><A><N><E><P><L><K><T><H><R><E>	May be required for cellular fusion during osteoclastogenesis.<BOP>	P57738
Q9NY37	ASIC5_HUMAN	Human intestine Na(+) channel	Homo	<M><E><Q><T><E><K><S><K><V><Y><A><E><N><G><L><L><E><K><I><K><L><C><L><S><K><K><P><L><P><S><P><T><E><R><K><K><F><D><H><D><F><A><I><S><T><S><F><H><G><I><H><N><I><V><Q><N><R><S><K><I><R><R><V><L><W><L><V><V><V><L><G><S><V><S><L><V><T><W><Q><I><Y><I><R><L><L><N><Y><F><T><W><P><T><T><T><S><I><E><V><Q><Y><V><E><K><M><E><F><P><A><V><T><F><C><N><L><N><R><F><Q><T><D><A><V><A><K><F><G><V><I><F><F><L><W><H><I><V><S><K><V><L><H><L><Q><E><I><T><A><N><S><T><G><S><R><E><A><T><D><F><A><A><S><H><Q><N><F><S><I><V><E><F><I><R><N><K><G><F><Y><L><N><N><S><T><L><L><D><C><E><F><F><G><K><P><C><S><P><K><D><F><A><H><V><F><T><E><Y><G><N><C><F><T><F><N><H><G><E><T><L><Q><A><K><R><K><V><S><V><S><G><R><G><L><S><L><L><F><N><V><N><Q><E><A><F><T><D><N><P><A><L><G><F><V><D><A><G><I><I><F><V><I><H><S><P><K><K><V><P><Q><F><D><G><L><G><L><L><S><P><V><G><M><H><A><R><V><T><I><R><Q><V><K><T><V><H><Q><E><Y><P><W><G><E><C><N><P><N><I><K><L><Q><N><F><S><S><Y><S><T><S><G><C><L><K><E><C><K><A><Q><H><I><K><K><Q><C><G><C><V><P><F><L><L><P><G><Y><G><I><E><C><D><L><Q><K><Y><F><S><C><V><S><P><V><L><D><H><I><E><F><K><D><L><C><T><V><G><T><H><N><S><S><C><P><V><S><C><E><E><I><E><Y><P><A><T><I><S><Y><S><S><F><P><S><Q><K><A><L><K><Y><L><S><K><K><L><N><Q><S><R><K><Y><I><R><E><N><L><V><K><I><E><I><N><Y><S><D><L><N><Y><K><I><T><Q><Q><Q><K><A><V><S><V><S><E><L><L><A><D><L><G><G><Q><L><G><L><F><C><G><A><S><L><I><T><I><I><E><I><I><E><Y><L><F><T><N><F><Y><W><I><C><I><F><F><L><L><K><I><S><E><M><T><Q><W><T><P><P><P><Q><N><H><L><G><N><K><N><R><I><E><E><C>	Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.<BOP>	Q9NY37
Q8N6I1	EID2_HUMAN	EID-1-like inhibitor of differentiation 2	Homo	<M><S><K><L><P><A><D><S><S><V><P><Q><T><G><A><A><N><G><D><R><D><V><P><Q><A><E><V><G><R><G><R><R><E><P><A><P><A><Q><P><E><E><A><G><E><G><A><M><A><A><A><R><G><G><P><V><P><A><A><R><E><G><R><M><A><A><A><R><A><A><P><A><A><A><A><R><G><A><P><V><A><A><A><A><L><A><R><A><A><A><A><G><R><E><S><P><A><A><A><A><A><R><E><A><R><M><A><E><V><A><R><L><L><G><E><P><V><D><E><E><G><P><E><G><R><P><R><S><R><H><G><N><G><G><L><A><A><L><P><Y><L><R><L><R><H><P><L><S><V><L><G><I><N><Y><Q><Q><F><L><R><H><Y><L><E><N><Y><P><I><A><P><G><R><I><Q><E><L><E><E><R><R><R><R><F><V><E><A><C><R><A><R><E><A><A><F><D><A><E><Y><Q><R><N><P><H><R><V><D><L><D><I><L><T><F><T><I><A><L><T><A><S><E><V><I><N><P><L><I><E><E><L><G><C><D><K><F><I><N><R><E>	Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.<BOP>	Q8N6I1
Q7RTS3	PTF1A_HUMAN	p48 DNA-binding subunit of transcription factor PTF1	Homo	<M><D><A><V><L><L><E><H><F><P><G><G><L><D><A><F><P><S><S><Y><F><D><E><D><D><F><F><T><D><Q><S><S><R><D><P><L><E><D><G><D><E><L><L><A><D><E><Q><A><E><V><E><F><L><S><H><Q><L><H><E><Y><C><Y><R><D><G><A><C><L><L><L><Q><P><A><P><P><A><A><P><L><A><L><A><P><P><S><S><G><G><L><G><E><P><D><D><G><G><G><G><G><Y><C><C><E><T><G><A><P><P><G><G><F><P><Y><S><P><G><S><P><P><S><C><L><A><Y><P><C><A><G><A><A><V><L><S><P><G><A><R><L><R><G><L><S><G><A><A><A><A><A><A><R><R><R><R><R><V><R><S><E><A><E><L><Q><Q><L><R><Q><A><A><N><V><R><E><R><R><R><M><Q><S><I><N><D><A><F><E><G><L><R><S><H><I><P><T><L><P><Y><E><K><R><L><S><K><V><D><T><L><R><L><A><I><G><Y><I><N><F><L><S><E><L><V><Q><A><D><L><P><L><R><G><G><G><A><G><G><C><G><G><P><G><G><G><G><R><L><G><G><D><S><P><G><S><Q><A><Q><K><V><I><I><C><H><R><G><T><R><S><P><S><P><S><D><P><D><Y><G><L><P><P><L><A><G><H><S><L><S><W><T><D><E><K><Q><L><K><E><Q><N><I><I><R><T><A><K><V><W><T><P><E><D><P><R><K><L><N><S><K><S><S><F><N><N><I><E><N><E><P><P><F><E><F><V><S>	Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.<BOP>	Q7RTS3
Q9UDX4	S14L3_HUMAN	Tocopherol-associated protein 2	Homo	<M><S><G><R><V><G><D><L><S><P><K><Q><A><E><T><L><A><K><F><R><E><N><V><Q><D><V><L><P><A><L><P><N><P><D><D><Y><F><L><L><R><W><L><R><A><R><N><F><D><L><Q><K><S><E><A><L><L><R><K><Y><M><E><F><R><K><T><M><D><I><D><H><I><L><D><W><Q><P><P><E><V><I><Q><K><Y><M><P><G><G><L><C><G><Y><D><R><D><G><C><P><V><W><Y><D><I><I><G><P><L><D><P><K><G><L><L><F><S><V><T><K><Q><D><L><L><K><T><K><M><R><D><C><E><R><I><L><H><E><C><D><L><Q><T><E><R><L><G><K><K><I><E><T><I><V><M><I><F><D><C><E><G><L><G><L><K><H><F><W><K><P><L><V><E><V><Y><Q><E><F><F><G><L><L><E><E><N><Y><P><E><T><L><K><F><M><L><I><V><K><A><T><K><L><F><P><V><G><Y><N><L><M><K><P><F><L><S><E><D><T><R><R><K><I><I><V><L><G><N><N><W><K><E><G><L><L><K><L><I><S><P><E><E><L><P><A><Q><F><G><G><T><L><T><D><P><D><G><N><P><K><C><L><T><K><I><N><Y><G><G><E><I><P><K><S><M><Y><V><R><D><Q><V><K><T><Q><Y><E><H><S><V><Q><I><N><R><G><S><S><H><Q><V><E><Y><E><I><L><F><P><G><C><V><L><R><W><Q><F><S><S><D><G><A><D><I><G><F><G><V><F><L><K><T><K><M><G><E><R><Q><R><A><G><E><M><T><D><V><L><P><S><Q><R><Y><N><A><H><M><V><P><E><D><G><N><L><T><C><S><E><A><G><V><Y><V><L><R><F><D><N><T><Y><S><F><V><H><A><K><K><V><S><F><T><V><E><V><L><L><P><D><E><G><M><Q><K><Y><D><K><E><L><T><P><V>	Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.<BOP>	Q9UDX4
O43869	OR2T1_HUMAN	Olfactory receptor OR1-61	Homo	<M><W><Q><E><Y><Y><F><L><N><V><F><F><P><L><L><K><V><C><C><L><T><I><N><S><H><V><V><I><L><L><P><W><E><C><Y><H><L><I><W><K><I><L><P><Y><I><G><T><T><V><G><S><M><E><E><Y><N><T><S><S><T><D><F><T><F><M><G><L><F><N><R><K><E><T><S><G><L><I><F><A><I><I><S><I><I><F><F><T><A><L><M><A><N><G><V><M><I><F><L><I><Q><T><D><L><R><L><H><T><P><M><Y><F><L><L><S><H><L><S><L><I><D><M><M><Y><I><S><T><I><V><P><K><M><L><V><N><Y><L><L><D><Q><R><T><I><S><F><V><G><C><T><A><Q><H><F><L><Y><L><T><L><V><G><A><E><F><F><L><L><G><L><M><A><Y><D><R><Y><V><A><I><C><N><P><L><R><Y><P><V><L><M><S><R><R><V><C><W><M><I><I><A><G><S><W><F><G><G><S><L><D><G><F><L><L><T><P><I><T><M><S><F><P><F><C><N><S><R><E><I><N><H><F><F><C><E><A><P><A><V><L><K><L><A><C><A><D><T><A><L><Y><E><T><V><M><Y><V><C><C><V><L><M><L><L><I><P><F><S><V><V><L><A><S><Y><A><R><I><L><T><T><V><Q><C><M><S><S><V><E><G><R><K><K><A><F><A><T><C><S><S><H><M><T><V><V><S><L><F><Y><G><A><A><M><Y><T><Y><M><L><P><H><S><Y><H><K><P><A><Q><D><K><V><L><S><V><F><Y><T><I><L><T><P><M><L><N><P><L><I><Y><S><L><R><N><K><D><V><T><G><A><L><K><R><A><L><G><R><F><K><G><P><Q><R><V><S><G><G><V><F>	Odorant receptor.<BOP>	O43869
O15551	CLD3_HUMAN	Rat ventral prostate.1 protein homolog	Homo	<M><S><M><G><L><E><I><T><G><T><A><L><A><V><L><G><W><L><G><T><I><V><C><C><A><L><P><M><W><R><V><S><A><F><I><G><S><N><I><I><T><S><Q><N><I><W><E><G><L><W><M><N><C><V><V><Q><S><T><G><Q><M><Q><C><K><V><Y><D><S><L><L><A><L><P><Q><D><L><Q><A><A><R><A><L><I><V><V><A><I><L><L><A><A><F><G><L><L><V><A><L><V><G><A><Q><C><T><N><C><V><Q><D><D><T><A><K><A><K><I><T><I><V><A><G><V><L><F><L><L><A><A><L><L><T><L><V><P><V><S><W><S><A><N><T><I><I><R><D><F><Y><N><P><V><V><P><E><A><Q><K><R><E><M><G><A><G><L><Y><V><G><W><A><A><A><A><L><Q><L><L><G><G><A><L><L><C><C><S><C><P><P><R><E><K><K><Y><T><A><T><K><V><V><Y><S><A><P><R><S><T><G><P><G><A><S><L><G><T><G><Y><D><R><K><D><Y><V>	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<BOP>	O15551
Q8NAT1	PMGT2_HUMAN	Glycosyltransferase-like domain-containing protein 2	Homo	<M><H><L><S><A><V><F><N><A><L><L><V><S><V><L><A><A><V><L><W><K><H><V><R><L><R><E><H><A><A><T><L><E><E><E><L><A><L><S><R><Q><A><T><E><P><A><P><A><L><R><I><D><Y><P><K><A><L><Q><I><L><M><E><G><G><T><H><M><V><C><T><G><R><T><H><T><D><R><I><C><R><F><K><W><L><C><Y><S><N><E><A><E><E><F><I><F><F><H><G><N><T><S><V><M><L><P><N><L><G><S><R><R><F><Q><P><A><L><L><D><L><S><T><V><E><D><H><N><T><Q><Y><F><N><F><V><E><L><P><A><A><A><L><R><F><M><P><K><P><V><F><V><P><D><V><A><L><I><A><N><R><F><N><P><D><N><L><M><H><V><F><H><D><D><L><L><P><L><F><Y><T><L><R><Q><F><P><G><L><A><H><E><A><R><L><F><F><M><E><G><W><G><E><G><A><H><F><D><L><Y><K><L><L><S><P><K><Q><P><L><L><R><A><Q><L><K><T><L><G><R><L><L><C><F><S><H><A><F><V><G><L><S><K><I><T><T><W><Y><Q><Y><G><F><V><Q><P><Q><G><P><K><A><N><I><L><V><S><G><N><E><I><R><Q><F><A><R><F><M><T><E><K><L><N><V><S><H><T><G><V><P><L><G><E><E><Y><I><L><V><F><S><R><T><Q><N><R><L><I><L><N><E><A><E><L><L><L><A><L><A><Q><E><F><Q><M><K><T><V><T><V><S><L><E><D><H><T><F><A><D><V><V><R><L><V><S><N><A><S><M><L><V><S><M><H><G><A><Q><L><V><T><T><L><F><L><P><R><G><A><T><V><V><E><L><F><P><Y><A><V><N><P><D><H><Y><T><P><Y><K><T><L><A><M><L><P><G><M><D><L><Q><Y><V><A><W><R><N><M><M><P><E><N><T><V><T><H><P><E><R><P><W><D><Q><G><G><I><T><H><L><D><R><A><E><Q><A><R><I><L><Q><S><R><E><V><P><R><H><L><C><C><R><N><P><E><W><L><F><R><I><Y><Q><D><T><K><V><D><I><P><S><L><I><Q><T><I><R><R><V><V><K><G><R><P><G><P><R><K><Q><K><W><T><V><G><L><Y><P><G><K><V><R><E><A><R><C><Q><A><S><V><H><G><A><S><E><A><R><L><T><V><S><W><Q><I><P><W><N><L><K><Y><L><K><V><R><E><V><K><Y><E><V><W><L><Q><E><Q><G><E><N><T><Y><V><P><Y><I><L><A><L><Q><N><H><T><F><T><E><N><I><K><P><F><T><T><Y><L><V><W><V><R><C><I><F><N><K><I><L><L><G><P><F><A><D><V><L><V><C><N><T>	O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.<BOP>	Q8NAT1
P20783	NTF3_HUMAN	Neurotrophic factor	Homo	<M><S><I><L><F><Y><V><I><F><L><A><Y><L><R><G><I><Q><G><N><N><M><D><Q><R><S><L><P><E><D><S><L><N><S><L><I><I><K><L><I><Q><A><D><I><L><K><N><K><L><S><K><Q><M><V><D><V><K><E><N><Y><Q><S><T><L><P><K><A><E><A><P><R><E><P><E><R><G><G><P><A><K><S><A><F><Q><P><V><I><A><M><D><T><E><L><L><R><Q><Q><R><R><Y><N><S><P><R><V><L><L><S><D><S><T><P><L><E><P><P><P><L><Y><L><M><E><D><Y><V><G><S><P><V><V><A><N><R><T><S><R><R><K><R><Y><A><E><H><K><S><H><R><G><E><Y><S><V><C><D><S><E><S><L><W><V><T><D><K><S><S><A><I><D><I><R><G><H><Q><V><T><V><L><G><E><I><K><T><G><N><S><P><V><K><Q><Y><F><Y><E><T><R><C><K><E><A><R><P><V><K><N><G><C><R><G><I><D><D><K><H><W><N><S><Q><C><K><T><S><Q><T><Y><V><R><A><L><T><S><E><N><N><K><L><V><G><W><R><W><I><R><I><D><T><S><C><V><C><A><L><S><R><K><I><G><R><T>	Seems to promote the survival of visceral and proprioceptive sensory neurons.<BOP>	P20783
Q13231	CHIT1_HUMAN	Chitinase-1	Homo	<M><V><R><S><V><A><W><A><G><F><M><V><L><L><M><I><P><W><G><S><A><A><K><L><V><C><Y><F><T><N><W><A><Q><Y><R><Q><G><E><A><R><F><L><P><K><D><L><D><P><S><L><C><T><H><L><I><Y><A><F><A><G><M><T><N><H><Q><L><S><T><T><E><W><N><D><E><T><L><Y><Q><E><F><N><G><L><K><K><M><N><P><K><L><K><T><L><L><A><I><G><G><W><N><F><G><T><Q><K><F><T><D><M><V><A><T><A><N><N><R><Q><T><F><V><N><S><A><I><R><F><L><R><K><Y><S><F><D><G><L><D><L><D><W><E><Y><P><G><S><Q><G><S><P><A><V><D><K><E><R><F><T><T><L><V><Q><D><L><A><N><A><F><Q><Q><E><A><Q><T><S><G><K><E><R><L><L><L><S><A><A><V><P><A><G><Q><T><Y><V><D><A><G><Y><E><V><D><K><I><A><Q><N><L><D><F><V><N><L><M><A><Y><D><F><H><G><S><W><E><K><V><T><G><H><N><S><P><L><Y><K><R><Q><E><E><S><G><A><A><A><S><L><N><V><D><A><A><V><Q><Q><W><L><Q><K><G><T><P><A><S><K><L><I><L><G><M><P><T><Y><G><R><S><F><T><L><A><S><S><S><D><T><R><V><G><A><P><A><T><G><S><G><T><P><G><P><F><T><K><E><G><G><M><L><A><Y><Y><E><V><C><S><W><K><G><A><T><K><Q><R><I><Q><D><Q><K><V><P><Y><I><F><R><D><N><Q><W><V><G><F><D><D><V><E><S><F><K><T><K><V><S><Y><L><K><Q><K><G><L><G><G><A><M><V><W><A><L><D><L><D><D><F><A><G><F><S><C><N><Q><G><R><Y><P><L><I><Q><T><L><R><Q><E><L><S><L><P><Y><L><P><S><G><T><P><E><L><E><V><P><K><P><G><Q><P><S><E><P><E><H><G><P><S><P><G><Q><D><T><F><C><Q><G><K><A><D><G><L><Y><P><N><P><R><E><R><S><S><F><Y><S><C><A><A><G><R><L><F><Q><Q><S><C><P><T><G><L><V><F><S><N><S><C><K><C><C><T><W><N>	Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<BOP>	Q13231
Q9NVF7	FBX28_HUMAN	F-box only protein 28	Homo	<M><A><A><A><A><E><E><R><M><A><E><E><G><G><G><G><Q><G><D><G><G><S><S><L><A><S><G><S><T><Q><R><Q><P><P><P><P><A><P><Q><H><P><Q><P><G><S><Q><A><L><P><A><P><A><L><A><P><D><Q><L><P><Q><N><N><T><L><V><A><L><P><I><V><A><I><E><N><I><L><S><F><M><S><Y><D><E><I><S><Q><L><R><L><V><C><K><R><M><D><L><V><C><Q><R><M><L><N><Q><G><F><L><K><V><E><R><Y><H><N><L><C><Q><K><Q><V><K><A><Q><L><P><R><R><E><S><E><R><R><N><H><S><L><A><R><H><A><D><I><L><A><A><V><E><T><R><L><S><L><L><N><M><T><F><M><K><Y><V><D><S><N><L><C><C><F><I><P><G><K><V><I><D><E><I><Y><R><V><L><R><Y><V><N><S><T><R><A><P><Q><R><A><H><E><V><L><Q><E><L><R><D><I><S><S><M><A><M><E><Y><F><D><E><K><I><V><P><I><L><K><R><K><L><P><G><S><D><V><S><G><R><L><M><G><S><P><P><V><P><G><P><S><A><A><L><T><T><M><Q><L><F><S><K><Q><N><P><S><R><Q><E><V><T><K><L><Q><Q><Q><V><K><T><N><G><A><G><V><T><V><L><R><R><E><I><S><E><L><R><T><K><V><Q><E><Q><Q><K><Q><L><Q><D><Q><D><Q><K><L><L><E><Q><T><Q><I><I><G><E><Q><N><A><R><L><A><E><L><E><R><K><L><R><E><V><M><E><S><A><V><G><N><S><S><G><S><G><Q><N><E><E><S><P><R><K><R><K><K><A><T><E><A><I><D><S><L><R><K><S><K><R><L><R><N><R><K>	Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.<BOP>	Q9NVF7
Q96K19	RN170_HUMAN	RING-type E3 ubiquitin transferase RNF170	Homo	<M><A><K><Y><Q><G><E><V><Q><S><L><K><L><D><D><D><S><V><I><E><G><V><S><D><Q><V><L><V><A><V><V><V><S><F><A><L><I><A><T><L><V><Y><A><L><F><R><N><V><H><Q><N><I><H><P><E><N><Q><E><L><V><R><V><L><R><E><Q><L><Q><T><E><Q><D><A><P><A><A><T><R><Q><Q><F><Y><T><D><M><Y><C><P><I><C><L><H><Q><A><S><F><P><V><E><T><N><C><G><H><L><F><C><G><A><C><I><I><A><Y><W><R><Y><G><S><W><L><G><A><I><S><C><P><I><C><R><Q><T><V><T><L><L><L><T><V><F><G><E><D><D><Q><S><Q><D><V><L><R><L><H><Q><D><I><N><D><Y><N><R><R><F><S><G><Q><P><R><S><I><M><E><R><I><M><D><L><P><T><L><L><R><H><A><F><R><E><M><F><S><V><G><G><L><F><W><M><F><R><I><R><I><I><L><C><L><M><G><A><F><F><Y><L><I><S><P><L><D><F><V><P><E><A><L><F><G><I><L><G><F><L><D><D><F><F><V><I><F><L><L><L><I><Y><I><S><I><M><Y><R><E><V><I><T><Q><R><L><T><R>	E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.<BOP>	Q96K19
Q02383	SEMG2_HUMAN	Semenogelin II	Homo	<M><K><S><I><I><L><F><V><L><S><L><L><L><I><L><E><K><Q><A><A><V><M><G><Q><K><G><G><S><K><G><Q><L><P><S><G><S><S><Q><F><P><H><G><Q><K><G><Q><H><Y><F><G><Q><K><D><Q><Q><H><T><K><S><K><G><S><F><S><I><Q><H><T><Y><H><V><D><I><N><D><H><D><W><T><R><K><S><Q><Q><Y><D><L><N><A><L><H><K><A><T><K><S><K><Q><H><L><G><G><S><Q><Q><L><L><N><Y><K><Q><E><G><R><D><H><D><K><S><K><G><H><F><H><M><I><V><I><H><H><K><G><G><Q><A><H><H><G><T><Q><N><P><S><Q><D><Q><G><N><S><P><S><G><K><G><L><S><S><Q><C><S><N><T><E><K><R><L><W><V><H><G><L><S><K><E><Q><A><S><A><S><G><A><Q><K><G><R><T><Q><G><G><S><Q><S><S><Y><V><L><Q><T><E><E><L><V><V><N><K><Q><Q><R><E><T><K><N><S><H><Q><N><K><G><H><Y><Q><N><V><V><D><V><R><E><E><H><S><S><K><L><Q><T><S><L><H><P><A><H><Q><D><R><L><Q><H><G><P><K><D><I><F><T><T><Q><D><E><L><L><V><Y><N><K><N><Q><H><Q><T><K><N><L><S><Q><D><Q><E><H><G><R><K><A><H><K><I><S><Y><P><S><S><R><T><E><E><R><Q><L><H><H><G><E><K><S><V><Q><K><D><V><S><K><G><S><I><S><I><Q><T><E><E><K><I><H><G><K><S><Q><N><Q><V><T><I><H><S><Q><D><Q><E><H><G><H><K><E><N><K><I><S><Y><Q><S><S><S><T><E><E><R><H><L><N><C><G><E><K><G><I><Q><K><G><V><S><K><G><S><I><S><I><Q><T><E><E><Q><I><H><G><K><S><Q><N><Q><V><R><I><P><S><Q><A><Q><E><Y><G><H><K><E><N><K><I><S><Y><Q><S><S><S><T><E><E><R><R><L><N><S><G><E><K><D><V><Q><K><G><V><S><K><G><S><I><S><I><Q><T><E><E><K><I><H><G><K><S><Q><N><Q><V><T><I><P><S><Q><D><Q><E><H><G><H><K><E><N><K><M><S><Y><Q><S><S><S><T><E><E><R><R><L><N><Y><G><G><K><S><T><Q><K><D><V><S><Q><S><S><I><S><F><Q><I><E><K><L><V><E><G><K><S><Q><I><Q><T><P><N><P><N><Q><D><Q><W><S><G><Q><N><A><K><G><K><S><G><Q><S><A><D><S><K><Q><D><L><L><S><H><E><Q><K><G><R><Y><K><Q><E><S><S><E><S><H><N><I><V><I><T><E><H><E><V><A><Q><D><D><H><L><T><Q><Q><Y><N><E><D><R><N><P><I><S><T>	Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.<BOP>	Q02383
Q8TDQ7	GNPI2_HUMAN	Glucosamine-6-phosphate isomerase SB52	Homo	<M><R><L><V><I><L><D><N><Y><D><L><A><S><E><W><A><A><K><Y><I><C><N><R><I><I><Q><F><K><P><G><Q><D><R><Y><F><T><L><G><L><P><T><G><S><T><P><L><G><C><Y><K><K><L><I><E><Y><H><K><N><G><H><L><S><F><K><Y><V><K><T><F><N><M><D><E><Y><V><G><L><P><R><N><H><P><E><S><Y><H><S><Y><M><W><N><N><F><F><K><H><I><D><I><D><P><N><N><A><H><I><L><D><G><N><A><A><D><L><Q><A><E><C><D><A><F><E><N><K><I><K><E><A><G><G><I><D><L><F><V><G><G><I><G><P><D><G><H><I><A><F><N><E><P><G><S><S><L><V><S><R><T><R><L><K><T><L><A><M><D><T><I><L><A><N><A><K><Y><F><D><G><D><L><S><K><V><P><T><M><A><L><T><V><G><V><G><T><V><M><D><A><R><E><V><M><I><L><I><T><G><A><H><K><A><F><A><L><Y><K><A><I><E><E><G><V><N><H><M><W><T><V><S><A><F><Q><Q><H><P><R><T><I><F><V><C><D><E><D><A><T><L><E><L><R><V><K><T><V><K><Y><F><K><G><L><M><H><V><H><N><K><L><V><D><P><L><F><S><M><K><D><G><N>	Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomerization mediating the metabolic flux from UDP-GlcNAc toward Fru-6P. At high ammonium level can drive amination and isomerization of Fru-6P toward hexosamines and UDP-GlcNAc synthesis. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and their effects on hyaluronan synthesis that occur during tissue remodeling.<BOP>	Q8TDQ7
Q5TFQ8	SIRBL_HUMAN	Signal-regulatory protein beta-1 isoform 3	Homo	<M><P><V><P><A><S><W><P><H><L><P><S><P><F><L><L><M><T><L><L><L><G><R><L><T><G><V><A><G><E><E><E><L><Q><V><I><Q><P><D><K><S><I><S><V><A><A><G><E><S><A><T><L><H><C><T><V><T><S><L><I><P><V><G><P><I><Q><W><F><R><G><A><G><P><G><R><E><L><I><Y><N><Q><K><E><G><H><F><P><R><V><T><T><V><S><D><L><T><K><R><N><N><M><D><F><S><I><R><I><S><N><I><T><P><A><D><A><G><T><Y><Y><C><V><K><F><R><K><G><S><P><D><H><V><E><F><K><S><G><A><G><T><E><L><S><V><R><A><K><P><S><A><P><V><V><S><G><P><A><A><R><A><T><P><Q><H><T><V><S><F><T><C><E><S><H><G><F><S><P><R><D><I><T><L><K><W><F><K><N><G><N><E><L><S><D><F><Q><T><N><V><D><P><A><G><D><S><V><S><Y><S><I><H><S><T><A><K><V><V><L><T><R><E><D><V><H><S><Q><V><I><C><E><V><A><H><V><T><L><Q><G><D><P><L><R><G><T><A><N><L><S><E><T><I><R><V><P><P><T><L><E><V><T><Q><Q><P><V><R><A><E><N><Q><V><N><V><T><C><Q><V><R><K><F><Y><P><Q><R><L><Q><L><T><W><L><E><N><G><N><V><S><R><T><E><T><A><S><T><L><T><E><N><K><D><G><T><Y><N><W><M><S><W><L><L><V><N><V><S><A><H><R><D><D><V><K><L><T><C><Q><V><E><H><D><G><Q><P><A><V><S><K><S><H><D><L><K><V><S><A><H><P><K><E><Q><G><S><N><T><A><P><G><P><A><L><A><S><A><A><P><L><L><I><A><F><L><L><G><P><K><V><L><L><V><V><G><V><S><V><I><Y><V><Y><W><K><Q><K><A>	Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.<BOP>	Q5TFQ8
P00414	COX3_HUMAN	Cytochrome c oxidase polypeptide III	Homo	<M><T><H><Q><S><H><A><Y><H><M><V><K><P><S><P><W><P><L><T><G><A><L><S><A><L><L><M><T><S><G><L><A><M><W><F><H><F><H><S><M><T><L><L><M><L><G><L><L><T><N><T><L><T><M><Y><Q><W><W><R><D><V><T><R><E><S><T><Y><Q><G><H><H><T><P><P><V><Q><K><G><L><R><Y><G><M><I><L><F><I><T><S><E><V><F><F><F><A><G><F><F><W><A><F><Y><H><S><S><L><A><P><T><P><Q><L><G><G><H><W><P><P><T><G><I><T><P><L><N><P><L><E><V><P><L><L><N><T><S><V><L><L><A><S><G><V><S><I><T><W><A><H><H><S><L><M><E><N><N><R><N><Q><M><I><Q><A><L><L><I><T><I><L><L><G><L><Y><F><T><L><L><Q><A><S><E><Y><F><E><S><P><F><T><I><S><D><G><I><Y><G><S><T><F><F><V><A><T><G><F><H><G><L><H><V><I><I><G><S><T><F><L><T><I><C><F><I><R><Q><L><M><F><H><F><T><S><K><H><H><F><G><F><E><A><A><A><W><Y><W><H><F><V><D><V><V><W><L><F><L><Y><V><S><I><Y><W><W><G><S>	Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from	P00414
O00567	NOP56_HUMAN	Nucleolar protein 5A	Homo	<M><V><L><L><H><V><L><F><E><H><A><V><G><Y><A><L><L><A><L><K><E><V><E><E><I><S><L><L><Q><P><Q><V><E><E><S><V><L><N><L><G><K><F><H><S><I><V><R><L><V><A><F><C><P><F><A><S><S><Q><V><A><L><E><N><A><N><A><V><S><E><G><V><V><H><E><D><L><R><L><L><L><E><T><H><L><P><S><K><K><K><K><V><L><L><G><V><G><D><P><K><I><G><A><A><I><Q><E><E><L><G><Y><N><C><Q><T><G><G><V><I><A><E><I><L><R><G><V><R><L><H><F><H><N><L><V><K><G><L><T><D><L><S><A><C><K><A><Q><L><G><L><G><H><S><Y><S><R><A><K><V><K><F><N><V><N><R><V><D><N><M><I><I><Q><S><I><S><L><L><D><Q><L><D><K><D><I><N><T><F><S><M><R><V><R><E><W><Y><G><Y><H><F><P><E><L><V><K><I><I><N><D><N><A><T><Y><C><R><L><A><Q><F><I><G><N><R><R><E><L><N><E><D><K><L><E><K><L><E><E><L><T><M><D><G><A><K><A><K><A><I><L><D><A><S><R><S><S><M><G><M><D><I><S><A><I><D><L><I><N><I><E><S><F><S><S><R><V><V><S><L><S><E><Y><R><Q><S><L><H><T><Y><L><R><S><K><M><S><Q><V><A><P><S><L><S><A><L><I><G><E><A><V><G><A><R><L><I><A><H><A><G><S><L><T><N><L><A><K><Y><P><A><S><T><V><Q><I><L><G><A><E><K><A><L><F><R><A><L><K><T><R><G><N><T><P><K><Y><G><L><I><F><H><S><T><F><I><G><R><A><A><A><K><N><K><G><R><I><S><R><Y><L><A><N><K><C><S><I><A><S><R><I><D><C><F><S><E><V><P><T><S><V><F><G><E><K><L><R><E><Q><V><E><E><R><L><S><F><Y><E><T><G><E><I><P><R><K><N><L><D><V><M><K><E><A><M><V><Q><A><E><E><A><A><A><E><I><T><R><K><L><E><K><Q><E><K><K><R><L><K><K><E><K><K><R><L><A><A><L><A><L><A><S><S><E><N><S><S><S><T><P><E><E><C><E><E><M><S><E><K><P><K><K><K><K><K><Q><K><P><Q><E><V><P><Q><E><N><G><M><E><D><P><S><I><S><F><S><K><P><K><K><K><K><S><F><S><K><E><E><L><M><S><S><D><L><E><E><T><A><G><S><T><S><I><P><K><R><K><K><S><T><P><K><E><E><T><V><N><D><P><E><E><A><G><H><R><S><G><S><K><K><K><R><K><F><S><K><E><E><P><V><S><S><G><P><E><E><A><V><G><K><S><S><S><K><K><K><K><K><F><H><K><A><S><Q><E><D>	Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.<BOP>	O00567
P38117	ETFB_HUMAN	Electron transfer flavoprotein subunit beta	Homo	<M><A><E><L><R><V><L><V><A><V><K><R><V><I><D><Y><A><V><K><I><R><V><K><P><D><R><T><G><V><V><T><D><G><V><K><H><S><M><N><P><F><C><E><I><A><V><E><E><A><V><R><L><K><E><K><K><L><V><K><E><V><I><A><V><S><C><G><P><A><Q><C><Q><E><T><I><R><T><A><L><A><M><G><A><D><R><G><I><H><V><E><V><P><P><A><E><A><E><R><L><G><P><L><Q><V><A><R><V><L><A><K><L><A><E><K><E><K><V><D><L><V><L><L><G><K><Q><A><I><D><D><D><C><N><Q><T><G><Q><M><T><A><G><F><L><D><W><P><Q><G><T><F><A><S><Q><V><T><L><E><G><D><K><L><K><V><E><R><E><I><D><G><G><L><E><T><L><R><L><K><L><P><A><V><V><T><A><D><L><R><L><N><E><P><R><Y><A><T><L><P><N><I><M><K><A><K><K><K><K><I><E><V><I><K><P><G><D><L><G><V><D><L><T><S><K><L><S><V><I><S><V><E><D><P><P><Q><R><T><A><G><V><K><V><E><T><T><E><D><L><V><A><K><L><K><E><I><G><R><I>	Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase . It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism . ETFB binds an AMP molecule that probably has a purely structural role .<BOP>	P38117
Q13823	NOG2_HUMAN	Autoantigen NGP-1	Homo	<M><V><K><P><K><Y><K><G><R><S><T><I><N><P><S><K><A><S><T><N><P><D><R><V><Q><G><A><G><G><Q><N><M><R><D><R><A><T><I><R><R><L><N><M><Y><R><Q><K><E><R><R><N><S><R><G><K><I><I><K><P><L><Q><Y><Q><S><T><V><A><S><G><T><V><A><R><V><E><P><N><I><K><W><F><G><N><T><R><V><I><K><Q><S><S><L><Q><K><F><Q><E><E><M><D><T><V><M><K><D><P><Y><K><V><V><M><K><Q><S><K><L><P><M><S><L><L><H><D><R><I><R><P><H><N><L><K><V><H><I><L><D><T><E><S><F><E><T><T><F><G><P><K><S><Q><R><K><R><P><N><L><F><A><S><D><M><Q><S><L><I><E><N><A><E><M><S><T><E><S><Y><D><Q><G><K><D><R><D><L><V><T><E><D><T><G><V><R><N><E><A><Q><E><E><I><Y><K><K><G><Q><S><K><R><I><W><G><E><L><Y><K><V><I><D><S><S><D><V><V><V><Q><V><L><D><A><R><D><P><M><G><T><R><S><P><H><I><E><T><Y><L><K><K><E><K><P><W><K><H><L><I><F><V><L><N><K><C><D><L><V><P><T><W><A><T><K><R><W><V><A><V><L><S><Q><D><Y><P><T><L><A><F><H><A><S><L><T><N><P><F><G><K><G><A><F><I><Q><L><L><R><Q><F><G><K><L><H><T><D><K><K><Q><I><S><V><G><F><I><G><Y><P><N><V><G><K><S><S><V><I><N><T><L><R><S><K><K><V><C><N><V><A><P><I><A><G><E><T><K><V><W><Q><Y><I><T><L><M><R><R><I><F><L><I><D><C><P><G><V><V><Y><P><S><E><D><S><E><T><D><I><V><L><K><G><V><V><Q><V><E><K><I><K><S><P><E><D><H><I><G><A><V><L><E><R><A><K><P><E><Y><I><S><K><T><Y><K><I><D><S><W><E><N><A><E><D><F><L><E><K><L><A><F><R><T><G><K><L><L><K><G><G><E><P><D><L><Q><T><V><G><K><M><V><L><N><D><W><Q><R><G><R><I><P><F><F><V><K><P><P><N><A><E><P><L><V><A><P><Q><L><L><P><S><S><S><L><E><V><V><P><E><A><A><Q><N><N><P><G><E><E><V><T><E><T><A><G><E><G><S><E><S><I><I><K><E><E><T><E><E><N><S><H><C><D><A><N><T><E><M><Q><Q><I><L><T><R><V><R><Q><N><F><G><K><I><N><V><V><P><Q><F><S><G><D><D><L><V><P><V><E><V><S><D><L><E><E><E><L><E><S><F><S><D><E><E><E><E><E><Q><E><Q><Q><R><D><D><A><E><E><S><S><S><E><P><E><E><E><N><V><G><N><D><T><K><A><V><I><K><A><L><D><E><K><I><A><K><Y><Q><K><F><L><D><K><A><K><A><K><K><F><S><A><V><R><I><S><K><G><L><S><E><K><I><F><A><K><P><E><E><Q><R><K><T><L><E><E><D><V><D><D><R><A><P><S><K><K><G><K><K><R><K><A><Q><R><E><E><E><Q><E><H><S><N><K><A><P><R><A><L><T><S><K><E><R><R><R><A><V><R><Q><Q><R><P><K><K><V><G><V><R><Y><Y><E><T><H><N><V><K><N><R><N><R><N><K><K><K><T><N><D><S><E><G><Q><K><H><K><R><K><K><F><R><Q><K><Q>	GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation . May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels .<BOP>	Q13823
P0DPB6	RPAC2_HUMAN	hRPA19	Homo	<M><E><E><D><Q><E><L><E><R><K><I><S><G><L><K><T><S><M><A><E><G><E><R><K><T><A><L><E><M><V><Q><A><A><G><T><D><R><H><C><V><T><F><V><L><H><E><E><D><H><T><L><G><N><S><L><R><Y><M><I><M><K><N><P><E><V><E><F><C><G><Y><T><T><T><H><P><S><E><S><K><I><N><L><R><I><Q><T><R><G><T><L><P><A><V><E><P><F><Q><R><G><L><N><E><L><M><N><V><C><Q><H><V><L><D><K><F><E><A><S><I><K><D><Y><K><D><Q><K><A><S><R><N><E><S><T><F>	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.<BOP>	P0DPB6
Q9H320	VCX1_HUMAN	Variably charged protein X-B1	Homo	<M><S><P><K><P><R><A><S><G><P><P><A><K><A><T><E><A><G><K><R><K><S><S><S><Q><P><S><P><S><D><P><K><K><K><T><T><K><V><A><K><K><G><K><A><V><R><R><G><R><R><G><K><K><G><A><A><T><K><M><A><A><V><T><A><P><E><A><E><S><A><P><A><A><P><G><P><S><D><Q><P><S><Q><E><L><P><Q><H><E><L><P><P><E><E><P><V><S><E><G><T><Q><H><D><P><L><S><Q><E><A><E><L><E><E><P><L><S><Q><E><S><E><V><E><E><P><L><S><Q><E><S><Q><V><E><E><P><L><S><Q><E><S><E><V><E><E><P><L><S><Q><E><S><Q><V><E><E><P><L><S><Q><E><S><E><V><E><E><P><L><S><Q><E><S><Q><V><E><E><P><L><S><Q><E><S><E><M><E><E><P><L><S><Q><E><S><Q><V><E><E><P><P><S><Q><E><S><E><M><E><E><L><P><S><V>	May mediate a process in spermatogenesis or may play a role in sex ratio distortion.<BOP>	Q9H320
Q5VZM2	RRAGB_HUMAN	Ras-related GTP-binding protein B	Homo	<M><E><E><S><D><S><E><K><T><T><E><K><E><N><L><G><P><R><M><D><P><P><L><G><E><P><E><G><S><L><G><W><V><L><P><N><T><A><M><K><K><K><V><L><L><M><G><K><S><G><S><G><K><T><S><M><R><S><I><I><F><A><N><Y><I><A><R><D><T><R><R><L><G><A><T><I><L><D><R><I><H><S><L><Q><I><N><S><S><L><S><T><Y><S><L><V><D><S><V><G><N><T><K><T><F><D><V><E><H><S><H><V><R><F><L><G><N><L><V><L><N><L><W><D><C><G><G><Q><D><T><F><M><E><N><Y><F><T><S><Q><R><D><N><I><F><R><N><V><E><V><L><I><Y><V><F><D><V><E><S><R><E><L><E><K><D><M><H><Y><Y><Q><S><C><L><E><A><I><L><Q><N><S><P><D><A><K><I><F><C><L><V><H><K><M><D><L><V><Q><E><D><Q><R><D><L><I><F><K><E><R><E><E><D><L><R><R><L><S><R><P><L><E><C><S><C><F><R><T><S><I><W><D><E><T><L><Y><K><A><W><S><S><I><V><Y><Q><L><I><P><N><V><Q><Q><L><E><M><N><L><R><N><F><A><E><I><I><E><A><D><E><V><L><L><F><E><R><A><T><F><L><V><I><S><H><Y><Q><C><K><E><Q><R><D><A><H><R><F><E><K><I><S><N><I><I><K><Q><F><K><L><S><C><S><K><L><A><A><S><F><Q><S><M><E><V><R><N><S><N><F><A><A><F><I><D><I><F><T><S><N><T><Y><V><M><V><V><M><S><D><P><S><I><P><S><A><A><T><L><I><N><I><R><N><A><R><K><H><F><E><K><L><E><R><V><D><G><P><K><Q><C><L><L><M><R>	Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade . Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form . In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB . Involved in the RCC1/Ran-GTPase pathway .<BOP>	Q5VZM2
P18627	LAG3_HUMAN	Secreted lymphocyte activation gene 3 protein	Homo	<M><W><E><A><Q><F><L><G><L><L><F><L><Q><P><L><W><V><A><P><V><K><P><L><Q><P><G><A><E><V><P><V><V><W><A><Q><E><G><A><P><A><Q><L><P><C><S><P><T><I><P><L><Q><D><L><S><L><L><R><R><A><G><V><T><W><Q><H><Q><P><D><S><G><P><P><A><A><A><P><G><H><P><L><A><P><G><P><H><P><A><A><P><S><S><W><G><P><R><P><R><R><Y><T><V><L><S><V><G><P><G><G><L><R><S><G><R><L><P><L><Q><P><R><V><Q><L><D><E><R><G><R><Q><R><G><D><F><S><L><W><L><R><P><A><R><R><A><D><A><G><E><Y><R><A><A><V><H><L><R><D><R><A><L><S><C><R><L><R><L><R><L><G><Q><A><S><M><T><A><S><P><P><G><S><L><R><A><S><D><W><V><I><L><N><C><S><F><S><R><P><D><R><P><A><S><V><H><W><F><R><N><R><G><Q><G><R><V><P><V><R><E><S><P><H><H><H><L><A><E><S><F><L><F><L><P><Q><V><S><P><M><D><S><G><P><W><G><C><I><L><T><Y><R><D><G><F><N><V><S><I><M><Y><N><L><T><V><L><G><L><E><P><P><T><P><L><T><V><Y><A><G><A><G><S><R><V><G><L><P><C><R><L><P><A><G><V><G><T><R><S><F><L><T><A><K><W><T><P><P><G><G><G><P><D><L><L><V><T><G><D><N><G><D><F><T><L><R><L><E><D><V><S><Q><A><Q><A><G><T><Y><T><C><H><I><H><L><Q><E><Q><Q><L><N><A><T><V><T><L><A><I><I><T><V><T><P><K><S><F><G><S><P><G><S><L><G><K><L><L><C><E><V><T><P><V><S><G><Q><E><R><F><V><W><S><S><L><D><T><P><S><Q><R><S><F><S><G><P><W><L><E><A><Q><E><A><Q><L><L><S><Q><P><W><Q><C><Q><L><Y><Q><G><E><R><L><L><G><A><A><V><Y><F><T><E><L><S><S><P><G><A><Q><R><S><G><R><A><P><G><A><L><P><A><G><H><L><L><L><F><L><I><L><G><V><L><S><L><L><L><L><V><T><G><A><F><G><F><H><L><W><R><R><Q><W><R><P><R><R><F><S><A><L><E><Q><G><I><H><P><P><Q><A><Q><S><K><I><E><E><L><E><Q><E><P><E><P><E><P><E><P><E><P><E><P><E><P><E><P><E><P><E><Q><L>	May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.<BOP>	P18627
A0A0C4DH35	HV335_HUMAN	Probable non-functional immunoglobulin heavy variable 3-35	Homo	<M><E><F><G><L><S><W><V><F><L><A><A><I><L><K><G><V><Q><C><E><V><Q><L><V><E><S><G><G><G><L><V><Q><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><S><N><S><D><M><N><W><V><H><Q><A><P><G><K><G><L><E><W><V><S><G><V><S><W><N><G><S><R><T><H><Y><A><D><S><V><K><G><R><F><I><I><S><R><D><N><S><R><N><T><L><Y><L><Q><T><N><S><L><R><A><E><D><T><A><V><Y><Y><C><V><R>	Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin heavy chains . Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection	A0A0C4DH35
Q5JSS6	MEIG1_HUMAN	Meiosis expressed gene 1 protein homolog	Homo	<M><A><S><S><D><V><K><P><K><S><V><S><H><A><K><K><W><S><E><E><I><E><N><L><Y><R><F><Q><Q><A><G><Y><R><D><E><T><E><Y><R><Q><V><K><Q><V><S><M><V><D><R><W><P><E><T><G><Y><V><K><K><L><Q><R><R><D><N><T><F><Y><Y><Y><N><K><Q><R><E><C><D><D><K><E><V><H><K><V><K><I><Y><A><Y>	Essential for spermiogenesis.<BOP>	Q5JSS6
Q6ZVK8	NUD18_HUMAN	Nucleoside diphosphate-linked moiety X motif 18	Homo	<M><A><S><E><G><L><A><G><A><L><A><S><V><L><A><G><Q><G><S><S><V><H><S><C><D><S><A><P><A><G><E><P><P><A><P><V><R><L><R><K><N><V><C><Y><V><V><L><A><V><F><L><S><E><Q><D><E><V><L><L><I><Q><E><A><K><R><E><C><R><G><S><W><Y><L><P><A><G><R><M><E><P><G><E><T><I><V><E><A><L><Q><R><E><V><K><E><E><A><G><L><H><C><E><P><E><T><L><L><S><V><E><E><R><G><P><S><W><V><R><F><V><F><L><A><R><P><T><G><G><I><L><K><T><S><K><E><A><D><A><E><S><L><Q><A><A><W><Y><P><R><T><S><L><P><T><P><L><R><A><H><D><I><L><H><L><V><E><L><A><A><Q><Y><R><Q><Q><A><R><H><P><L><I><L><P><Q><E><L><P><C><D><L><V><C><Q><R><L><V><A><T><F><T><S><A><Q><T><V><W><V><L><V><G><T><V><G><M><P><H><L><P><V><T><A><C><G><L><D><P><M><E><Q><R><G><G><M><K><M><A><V><L><R><L><L><Q><E><C><L><T><L><H><H><L><V><V><E><I><K><G><L><L><G><L><Q><H><L><G><R><D><H><S><D><G><I><C><L><N><V><L><V><T><V><A><F><R><S><P><G><I><Q><D><E><P><P><K><V><R><G><E><N><F><S><W><W><K><V><M><E><E><D><L><Q><S><Q><L><L><Q><R><L><Q><G><S><S><V><V><P><V><N><R>	Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools.<BOP>	Q6ZVK8
Q8IXM3	RM41_HUMAN	Mitochondrial large ribosomal subunit protein mL41	Homo	<M><G><V><L><A><A><A><A><R><C><L><V><R><G><A><D><R><M><S><K><W><T><S><K><R><G><P><R><S><F><R><G><R><K><G><R><G><A><K><G><I><G><F><L><T><S><G><W><R><F><V><Q><I><K><E><M><V><P><E><F><V><V><P><D><L><T><G><F><K><L><K><P><Y><V><S><Y><L><A><P><E><S><E><E><T><P><L><T><A><A><Q><L><F><S><E><A><V><A><P><A><I><E><K><D><F><K><D><G><T><F><D><P><D><N><L><E><K><Y><G><F><E><P><T><Q><E><G><K><L><F><Q><L><Y><P><R><N><F><L><R>	Component of the mitochondrial ribosome large subunit . Also involved in apoptosis and cell cycle . Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins .<BOP>	Q8IXM3
Q96MB7	HARB1_HUMAN	Harbinger transposase-derived nuclease	Homo	<M><A><I><P><I><T><V><L><D><C><D><L><L><L><Y><G><R><G><H><R><T><L><D><R><F><K><L><D><D><V><T><D><E><Y><L><M><S><M><Y><G><F><P><R><Q><F><I><Y><Y><L><V><E><L><L><G><A><N><L><S><R><P><T><Q><R><S><R><A><I><S><P><E><T><Q><V><L><A><A><L><G><F><Y><T><S><G><S><F><Q><T><R><M><G><D><A><I><G><I><S><Q><A><S><M><S><R><C><V><A><N><V><T><E><A><L><V><E><R><A><S><Q><F><I><R><F><P><A><D><E><A><S><I><Q><A><L><K><D><E><F><Y><G><L><A><G><M><P><G><V><M><G><V><V><D><C><I><H><V><A><I><K><A><P><N><A><E><D><L><S><Y><V><N><R><K><G><L><H><S><L><N><C><L><M><V><C><D><I><R><G><T><L><M><T><V><E><T><N><W><P><G><S><L><Q><D><C><A><V><L><Q><Q><S><S><L><S><S><Q><F><E><A><G><M><H><K><D><S><W><L><L><G><D><S><S><F><F><L><R><T><W><L><M><T><P><L><H><I><P><E><T><P><A><E><Y><R><Y><N><M><A><H><S><A><T><H><S><V><I><E><K><T><F><R><T><L><C><S><R><F><R><C><L><D><G><S><K><G><A><L><Q><Y><S><P><E><K><S><S><H><I><I><L><A><C><C><V><L><H><N><I><S><L><E><H><G><M><D><V><W><S><S><P><M><T><G><P><M><E><Q><P><P><E><E><E><Y><E><H><M><E><S><L><D><L><E><A><D><R><I><R><Q><E><L><M><L><T><H><F><S>	Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.<BOP>	Q96MB7
Q14520	HABP2_HUMAN	Hyaluronan-binding protein 2 27 kDa light chain alternate form	Homo	<M><F><A><R><M><S><D><L><H><V><L><L><L><M><A><L><V><G><K><T><A><C><G><F><S><L><M><S><L><L><E><S><L><D><P><D><W><T><P><D><Q><Y><D><Y><S><Y><E><D><Y><N><Q><E><E><N><T><S><S><T><L><T><H><A><E><N><P><D><W><Y><Y><T><E><D><Q><A><D><P><C><Q><P><N><P><C><E><H><G><G><D><C><L><V><H><G><S><T><F><T><C><S><C><L><A><P><F><S><G><N><K><C><Q><K><V><Q><N><T><C><K><D><N><P><C><G><R><G><Q><C><L><I><T><Q><S><P><P><Y><Y><R><C><V><C><K><H><P><Y><T><G><P><S><C><S><Q><V><V><P><V><C><R><P><N><P><C><Q><N><G><A><T><C><S><R><H><K><R><R><S><K><F><T><C><A><C><P><D><Q><F><K><G><K><F><C><E><I><G><S><D><D><C><Y><V><G><D><G><Y><S><Y><R><G><K><M><N><R><T><V><N><Q><H><A><C><L><Y><W><N><S><H><L><L><L><Q><E><N><Y><N><M><F><M><E><D><A><E><T><H><G><I><G><E><H><N><F><C><R><N><P><D><A><D><E><K><P><W><C><F><I><K><V><T><N><D><K><V><K><W><E><Y><C><D><V><S><A><C><S><A><Q><D><V><A><Y><P><E><E><S><P><T><E><P><S><T><K><L><P><G><F><D><S><C><G><K><T><E><I><A><E><R><K><I><K><R><I><Y><G><G><F><K><S><T><A><G><K><H><P><W><Q><A><S><L><Q><S><S><L><P><L><T><I><S><M><P><Q><G><H><F><C><G><G><A><L><I><H><P><C><W><V><L><T><A><A><H><C><T><D><I><K><T><R><H><L><K><V><V><L><G><D><Q><D><L><K><K><E><E><F><H><E><Q><S><F><R><V><E><K><I><F><K><Y><S><H><Y><N><E><R><D><E><I><P><H><N><D><I><A><L><L><K><L><K><P><V><D><G><H><C><A><L><E><S><K><Y><V><K><T><V><C><L><P><D><G><S><F><P><S><G><S><E><C><H><I><S><G><W><G><V><T><E><T><G><K><G><S><R><Q><L><L><D><A><K><V><K><L><I><A><N><T><L><C><N><S><R><Q><L><Y><D><H><M><I><D><D><S><M><I><C><A><G><N><L><Q><K><P><G><Q><D><T><C><Q><G><D><S><G><G><P><L><T><C><E><K><D><G><T><Y><Y><V><Y><G><I><V><S><W><G><L><E><C><G><K><R><P><G><V><Y><T><Q><V><T><K><F><L><N><W><I><K><A><T><I><K><S><E><S><G><F>	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII . May function as a tumor suppressor negatively regulating cell proliferation and cell migration .<BOP>	Q14520
Q9H8H0	NOL11_HUMAN	Nucleolar protein 11	Homo	<M><A><A><L><E><E><E><F><T><L><S><S><V><V><L><S><A><G><P><E><G><L><L><G><V><E><Q><S><D><K><T><D><Q><F><L><V><T><D><S><G><R><T><V><I><L><Y><K><V><S><D><Q><K><P><L><G><S><W><S><V><K><Q><G><Q><I><I><T><C><P><A><V><C><N><F><Q><T><G><E><Y><V><V><V><H><D><N><K><V><L><R><I><W><N><N><E><D><V><N><L><D><K><V><F><K><A><T><L><S><A><E><V><Y><R><I><L><S><V><Q><G><T><E><P><L><V><L><F><K><E><G><A><V><R><G><L><E><A><L><L><A><D><P><Q><Q><K><I><E><T><V><I><S><D><E><E><V><I><K><W><T><K><F><F><V><V><F><R><H><P><V><L><I><F><I><T><E><K><H><G><N><Y><F><A><Y><V><Q><M><F><N><S><R><I><L><T><K><Y><T><L><L><L><G><Q><D><E><N><S><V><I><K><S><F><T><A><S><V><D><R><K><F><I><S><L><M><S><L><S><S><D><G><C><I><Y><E><T><L><I><P><I><R><P><A><D><P><E><K><N><Q><S><L><V><K><S><L><L><L><K><A><V><V><S><G><N><A><R><N><G><V><A><L><T><A><L><D><Q><D><H><V><A><V><L><G><S><P><L><A><A><S><K><E><C><L><S><V><W><N><I><K><F><Q><T><L><Q><T><S><K><E><L><P><Q><G><T><S><G><Q><L><W><Y><Y><G><E><H><L><F><M><L><H><G><K><S><L><T><V><I><P><Y><K><C><E><V><S><S><L><A><G><A><L><G><K><L><K><H><S><Q><D><P><G><T><H><V><V><S><H><F><V><N><W><E><T><P><Q><G><C><G><L><G><F><Q><N><S><E><Q><S><R><R><I><L><R><R><R><K><I><E><V><S><L><Q><P><E><V><P><P><S><K><Q><L><L><S><T><I><M><K><D><S><E><K><H><I><E><V><E><V><R><K><F><L><A><L><K><Q><T><P><D><F><H><T><V><I><G><D><T><V><T><G><L><L><E><R><C><K><A><E><P><S><F><Y><P><R><N><C><L><M><Q><L><I><Q><T><H><V><L><S><Y><S><L><C><P><D><L><M><E><I><A><L><K><K><K><D><V><Q><L><L><Q><L><C><L><Q><Q><F><P><D><I><P><E><S><V><T><C><A><C><L><K><I><F><L><S><I><G><D><D><S><L><Q><E><T><D><V><N><M><E><S><V><F><D><Y><S><I><N><S><V><H><D><E><K><M><E><E><Q><T><E><I><L><Q><N><G><F><N><P><E><E><D><K><C><N><N><C><D><Q><E><L><N><K><K><P><Q><D><E><T><K><E><S><T><S><C><P><V><V><Q><K><R><A><A><L><L><N><A><I><L><H><S><A><Y><S><E><T><F><L><L><P><H><L><K><D><I><P><A><Q><H><I><T><L><F><L><K><Y><L><Y><F><L><Y><L><K><C><S><E><N><A><T><M><T><L><P><G><I><H><P><P><T><L><N><Q><I><M><D><W><I><C><L><L><L><D><A><N><F><T><V><V><V><M><M><P><E><A><K><R><L><L><I><N><L><Y><K><L><V><K><S><Q><I><S><V><Y><S><E><L><N><K><I><E><V><S><F><R><E><L><Q><K><L><N><Q><E><K><N><N><R><G><L><Y><S><I><E><V><L><E><L><F>	Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b.<BOP>	Q9H8H0
Q86V86	PIM3_HUMAN	Serine/threonine-protein kinase pim-3	Homo	<M><L><L><S><K><F><G><S><L><A><H><L><C><G><P><G><G><V><D><H><L><P><V><K><I><L><Q><P><A><K><A><D><K><E><S><F><E><K><A><Y><Q><V><G><A><V><L><G><S><G><G><F><G><T><V><Y><A><G><S><R><I><A><D><G><L><P><V><A><V><K><H><V><V><K><E><R><V><T><E><W><G><S><L><G><G><A><T><V><P><L><E><V><V><L><L><R><K><V><G><A><A><G><G><A><R><G><V><I><R><L><L><D><W><F><E><R><P><D><G><F><L><L><V><L><E><R><P><E><P><A><Q><D><L><F><D><F><I><T><E><R><G><A><L><D><E><P><L><A><R><R><F><F><A><Q><V><L><A><A><V><R><H><C><H><S><C><G><V><V><H><R><D><I><K><D><E><N><L><L><V><D><L><R><S><G><E><L><K><L><I><D><F><G><S><G><A><L><L><K><D><T><V><Y><T><D><F><D><G><T><R><V><Y><S><P><P><E><W><I><R><Y><H><R><Y><H><G><R><S><A><T><V><W><S><L><G><V><L><L><Y><D><M><V><C><G><D><I><P><F><E><Q><D><E><E><I><L><R><G><R><L><L><F><R><R><R><V><S><P><E><C><Q><Q><L><I><R><W><C><L><S><L><R><P><S><E><R><P><S><L><D><Q><I><A><A><H><P><W><M><L><G><A><D><G><G><V><P><E><S><C><D><L><R><L><C><T><L><D><P><D><D><V><A><S><T><T><S><S><S><E><S><L>	Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.<BOP>	Q86V86
P01599	KV117_HUMAN	Ig kappa chain V-I region WEA	Homo	<M><D><M><R><V><P><A><Q><L><L><G><L><L><L><L><W><F><P><G><A><R><C><D><I><Q><M><T><Q><S><P><S><S><L><S><A><S><V><G><D><R><V><T><I><T><C><R><A><S><Q><G><I><R><N><D><L><G><W><Y><Q><Q><K><P><G><K><A><P><K><R><L><I><Y><A><A><S><S><L><Q><S><G><V><P><S><R><F><S><G><S><G><S><G><T><E><F><T><L><T><I><S><S><L><Q><P><E><D><F><A><T><Y><Y><C><L><Q><H><N><S><Y><P>	V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen .<BOP>	P01599
P40121	CAPG_HUMAN	Actin regulatory protein CAP-G	Homo	<M><Y><T><A><I><P><Q><S><G><S><P><F><P><G><S><V><Q><D><P><G><L><H><V><W><R><V><E><K><L><K><P><V><P><V><A><Q><E><N><Q><G><V><F><F><S><G><D><S><Y><L><V><L><H><N><G><P><E><E><V><S><H><L><H><L><W><I><G><Q><Q><S><S><R><D><E><Q><G><A><C><A><V><L><A><V><H><L><N><T><L><L><G><E><R><P><V><Q><H><R><E><V><Q><G><N><E><S><D><L><F><M><S><Y><F><P><R><G><L><K><Y><Q><E><G><G><V><E><S><A><F><H><K><T><S><T><G><A><P><A><A><I><K><K><L><Y><Q><V><K><G><K><K><N><I><R><A><T><E><R><A><L><N><W><D><S><F><N><T><G><D><C><F><I><L><D><L><G><Q><N><I><F><A><W><C><G><G><K><S><N><I><L><E><R><N><K><A><R><D><L><A><L><A><I><R><D><S><E><R><Q><G><K><A><Q><V><E><I><V><T><D><G><E><E><P><A><E><M><I><Q><V><L><G><P><K><P><A><L><K><E><G><N><P><E><E><D><L><T><A><D><K><A><N><A><Q><A><A><A><L><Y><K><V><S><D><A><T><G><Q><M><N><L><T><K><V><A><D><S><S><P><F><A><L><E><L><L><I><S><D><D><C><F><V><L><D><N><G><L><C><G><K><I><Y><I><W><K><G><R><K><A><N><E><K><E><R><Q><A><A><L><Q><V><A><E><G><F><I><S><R><M><Q><Y><A><P><N><T><Q><V><E><I><L><P><Q><G><H><E><S><P><I><F><K><Q><F><F><K><D><W><K>	Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.<BOP>	P40121
Q96AB6	NTAN1_HUMAN	Protein NH2-terminal asparagine deamidase	Homo	<M><P><L><L><V><E><G><R><R><V><R><L><P><Q><S><A><G><D><L><V><R><A><H><P><P><L><E><E><R><A><R><L><L><R><G><Q><S><V><Q><Q><V><G><P><Q><G><L><L><Y><V><Q><Q><R><E><L><A><V><T><S><P><K><D><G><S><I><S><I><L><G><S><D><D><A><T><T><C><H><I><V><V><L><R><H><T><G><N><G><A><T><C><L><T><H><C><D><G><T><D><T><K><A><E><V><P><L><I><M><N><S><I><K><S><F><S><D><H><A><Q><C><G><R><L><E><V><H><L><V><G><G><F><S><D><D><R><Q><L><S><Q><K><L><T><H><Q><L><L><S><E><F><D><R><Q><E><D><D><I><H><L><V><T><L><C><V><T><E><L><N><D><R><E><E><N><E><N><H><F><P><V><I><Y><G><I><A><V><N><I><K><T><A><E><I><Y><R><A><S><F><Q><D><R><G><P><E><E><Q><L><R><A><A><R><T><L><A><G><G><P><M><I><S><I><Y><D><A><E><T><E><Q><L><R><I><G><P><Y><S><W><T><P><F><P><H><V><D><F><W><L><H><Q><D><D><K><Q><I><L><E><N><L><S><T><S><P><L><A><E><P><P><H><F><V><E><H><I><R><S><T><L><M><F><L><K><K><H><P><S><P><A><H><T><L><F><S><G><N><K><A><L><L><Y><K><K><N><E><D><G><L><W><E><K><I><S><S><P><G><S>	N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn.<BOP>	Q96AB6
Q9BYI3	HYCCI_HUMAN	Protein FAM126A	Homo	<M><F><T><S><E><K><G><V><V><E><E><W><L><S><E><F><K><T><L><P><E><T><S><L><P><N><Y><A><T><N><L><K><D><K><S><S><L><V><S><S><L><Y><K><V><I><Q><E><P><Q><S><E><L><L><E><P><V><C><H><Q><L><F><E><F><Y><R><S><G><E><E><Q><L><L><Q><F><T><L><Q><F><L><P><E><L><I><W><C><Y><L><A><V><S><A><S><R><N><V><H><S><S><G><C><I><E><A><L><L><L><G><V><Y><N><L><E><I><V><D><K><Q><G><H><T><K><V><L><S><F><T><I><P><S><L><S><K><P><S><V><Y><H><E><P><S><S><I><G><S><M><A><L><T><E><S><A><L><S><Q><H><G><L><S><K><V><V><Y><S><G><P><H><P><Q><R><E><M><L><T><A><Q><N><R><F><E><V><L><T><F><L><L><L><C><Y><N><A><A><L><T><Y><M><P><S><V><S><L><Q><S><L><C><Q><I><C><S><R><I><C><V><C><G><Y><P><R><Q><H><V><R><K><Y><K><G><I><S><S><R><I><P><V><S><S><G><F><M><V><Q><M><L><T><G><I><Y><F><A><F><Y><N><G><E><W><D><L><A><Q><K><A><L><D><D><I><I><Y><R><A><Q><L><E><L><Y><P><E><P><L><L><V><A><N><A><I><K><A><S><L><P><H><G><P><M><K><S><N><K><E><G><T><R><C><I><Q><V><E><I><T><P><T><S><S><R><I><S><R><N><A><V><T><S><M><S><I><R><G><H><R><W><K><R><H><G><N><T><E><L><T><G><Q><E><E><L><M><E><I><S><E><V><D><E><G><F><Y><S><R><A><A><S><S><T><S><Q><S><G><L><S><N><S><S><H><N><C><S><N><K><P><S><I><G><K><N><H><R><R><S><G><G><S><K><T><G><G><K><E><K><E><T><T><G><E><S><C><K><D><H><F><A><R><K><Q><T><Q><R><A><Q><S><E><N><L><E><L><L><S><L><K><R><L><T><L><T><T><S><Q><S><L><P><K><P><S><S><H><G><L><A><K><T><A><A><T><V><F><S><K><S><F><E><Q><V><S><G><V><T><V><P><H><N><P><S><S><A><V><G><C><G><A><G><T><D><A><N><R><F><S><A><C><S><L><Q><E><E><K><L><I><Y><V><S><E><R><T><E><L><P><M><K><H><Q><S><G><Q><Q><R><P><P><S><I><S><I><T><L><S><T><D>	Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane . The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis . FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P . Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system . May also have a role in the beta-catenin/Lef signaling pathway (Probable).<BOP>	Q9BYI3
Q3SY17	S2552_HUMAN	Solute carrier family 25 member 52	Homo	<M><I><D><S><E><A><H><E><K><R><P><P><I><L><T><S><S><K><Q><D><I><S><P><H><I><T><N><V><G><E><M><K><H><Y><L><C><G><C><C><A><A><F><N><N><V><A><I><T><Y><P><I><Q><K><V><L><F><R><Q><Q><L><Y><G><I><K><T><R><D><A><V><L><Q><L><R><R><D><G><F><R><N><L><Y><R><G><I><L><P><P><L><M><Q><K><T><T><T><L><A><L><M><F><G><L><Y><E><D><L><S><C><L><L><R><K><H><V><R><A><P><E><F><A><T><H><G><V><A><A><V><L><A><G><T><A><E><A><I><F><T><P><L><E><R><V><Q><T><L><L><Q><N><H><K><H><H><D><K><F><T><N><T><Y><Q><A><F><K><A><L><K><C><H><G><I><G><E><Y><Y><R><G><L><V><P><I><L><F><R><N><G><L><S><N><V><L><F><F><G><L><R><G><P><I><K><E><H><L><P><T><A><T><T><H><S><A><H><L><V><N><D><F><I><G><G><G><L><L><G><A><M><L><G><F><L><C><F><P><I><N><V><V><K><T><R><L><Q><S><Q><I><G><G><E><F><Q><S><F><P><K><V><F><Q><K><I><W><L><E><R><D><R><K><L><I><N><L><F><R><G><A><H><L><N><Y><H><R><S><L><I><S><W><G><I><I><N><A><T><Y><E><F><L><L><K><F><I>	Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria . Compared to SLC25A51, SLC25A52-mediated transport is not essential for the import of NAD(+) in mitochondria .<BOP>	Q3SY17
Q2WGJ8	TM249_HUMAN	Transmembrane protein 249	Homo	<M><P><K><G><R><A><G><S><L><P><T><T><S><I><G><W><R><F><Q><L><W><F><L><G><L><T><C><P><E><R><H><L><A><R><R><L><K><N><N><S><F><Y><P><F><V><Q><Q><E><P><N><V><F><V><L><E><Y><Y><L><D><T><L><W><K><G><M><L><L><F><I><I><S><V><V><L><V><S><F><S><S><L><R><E><V><Q><K><Q><E><T><W><V><F><L><V><Y><G><V><G><V><G><L><W><L><V><I><S><S><L><P><R><R><R><L><V><L><N><H><T><R><G><V><Y><H><F><S><I><Q><G><R><T><V><C><Q><G><P><L><H><L><V><Y><V><R><L><A><L><S><S><D><A><H><G><R><C><F><F><H><L><V><L><G><G><H><R><L><E><P><L><V><L><V><Q><L><S><E><H><Y><E><Q><M><E><Y><L><G><R><Y><I><A><R><K><L><N><I><N><Y><F><D><Y><L><A><T><S><Y><R><H><V><V><R><H><W><P><P><P><G><A><G><T><V><M><G><K><S><P><M><G><H><K><P><S><S><S><Q><S><S><L><E><V>	Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.<BOP>	Q2WGJ8

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