accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P06307 | CCKN_HUMAN | Cholecystokinin-5 | Homo | <M><N><S><G><V><C><L><C><V><L><M><A><V><L><A><A><G><A><L><T><Q><P><V><P><P><A><D><P><A><G><S><G><L><Q><R><A><E><E><A><P><R><R><Q><L><R><V><S><Q><R><T><D><G><E><S><R><A><H><L><G><A><L><L><A><R><Y><I><Q><Q><A><R><K><A><P><S><G><R><M><S><I><V><K><N><L><Q><N><L><D><P><S><H><R><I><S><D><R><D><Y><M><G><W><M><D><F><G><R><R><S... | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.<BOP> | P06307 |
O95070 | YIF1A_HUMAN | YIP1-interacting factor homolog A | Homo | <M><A><Y><H><S><G><Y><G><A><H><G><S><K><H><R><A><R><A><A><P><D><P><P><P><L><F><D><D><T><S><G><G><Y><S><S><Q><P><G><G><Y><P><A><T><G><A><D><V><A><F><S><V><N><H><L><L><G><D><P><M><A><N><V><A><M><A><Y><G><S><S><I><A><S><H><G><K><D><M><V><H><K><E><L><H><R><F><V><S><V><S><K><L><K><Y><F><F><A><V><D><T><A><Y><V><A><K><K><L><G... | Possible role in transport between endoplasmic reticulum and Golgi.<BOP> | O95070 |
Q9BRK3 | MXRA8_HUMAN | Limitrin | Homo | <M><A><L><P><S><R><I><L><L><W><K><L><V><L><L><Q><S><S><A><V><L><L><H><S><G><S><S><V><P><A><A><A><G><S><S><V><V><S><E><S><A><V><S><W><E><A><G><A><R><A><V><L><R><C><Q><S><P><R><M><V><W><T><Q><D><R><L><H><D><R><Q><R><V><L><H><W><D><L><R><G><P><G><G><G><P><A><R><R><L><L><D><L><Y><S><A><G><E><Q><R><V><Y><E><A><R><D><R><G><R... | (Microbial infection) Contributes to arthritogenic alphavirus pathogenesis and acts as a receptor for these viruses.<BOP> | Q9BRK3 |
O95154 | ARK73_HUMAN | AFB1 aldehyde reductase 2 | Homo | <M><S><R><Q><L><S><R><A><R><P><A><T><V><L><G><A><M><E><M><G><R><R><M><D><A><P><T><S><A><A><V><T><R><A><F><L><E><R><G><H><T><E><I><D><T><A><F><V><Y><S><E><G><Q><S><E><T><I><L><G><G><L><G><L><R><L><G><G><S><D><C><R><V><K><I><D><T><K><A><I><P><L><F><G><N><S><L><K><P><D><S><L><R><F><Q><L><E><T><S><L><K><R><L><Q><C><P><R><V... | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.<BOP> | O95154 |
Q68DH5 | LMBD2_HUMAN | LMBR1 domain-containing protein 2 | Homo | <M><S><G><A><A><L><G><L><E><I><V><F><V><F><F><L><A><L><F><L><L><H><R><Y><G><D><F><K><K><Q><H><R><L><V><I><I><G><T><L><L><A><W><Y><L><C><F><L><I><V><F><I><L><P><L><D><V><S><T><T><I><Y><N><R><C><K><H><A><A><A><N><S><S><P><P><E><N><S><N><I><T><G><L><Y><A><T><A><N><P><V><P><S><Q><H><P><C><F><K><P><W><S><Y><I><P><D><G><I><M... | Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway . May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable).<BOP> | Q68DH5 |
Q96IU4 | ABHEB_HUMAN | CCG1-interacting factor B | Homo | <M><A><A><S><V><E><Q><R><E><G><T><I><Q><V><Q><G><Q><A><L><F><F><R><E><A><L><P><G><S><G><Q><A><R><F><S><V><L><L><L><H><G><I><R><F><S><S><E><T><W><Q><N><L><G><T><L><H><R><L><A><Q><A><G><Y><R><A><V><A><I><D><L><P><G><L><G><H><S><K><E><A><A><A><P><A><P><I><G><E><L><A><P><G><S><F><L><A><A><V><V><D><A><L><E><L><G><P><P><V><V... | Acts as an atypical protein-lysine deacetylase in vitro . Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues . Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hy... | Q96IU4 |
P14384 | CBPM_HUMAN | Carboxypeptidase M | Homo | <M><D><F><P><C><L><W><L><G><L><L><L><P><L><V><A><A><L><D><F><N><Y><H><R><Q><E><G><M><E><A><F><L><K><T><V><A><Q><N><Y><S><S><V><T><H><L><H><S><I><G><K><S><V><K><G><R><N><L><W><V><L><V><V><G><R><F><P><K><E><H><R><I><G><I><P><E><F><K><Y><V><A><N><M><H><G><D><E><T><V><G><R><E><L><L><L><H><L><I><D><Y><L><V><T><S><D><G><K><D... | Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.<BOP> | P14384 |
Q99962 | SH3G2_HUMAN | SH3 domain-containing GRB2-like protein 2 | Homo | <M><S><V><A><G><L><K><K><Q><F><H><K><A><T><Q><K><V><S><E><K><V><G><G><A><E><G><T><K><L><D><D><D><F><K><E><M><E><R><K><V><D><V><T><S><R><A><V><M><E><I><M><T><K><T><I><E><Y><L><Q><P><N><P><A><S><R><A><K><L><S><M><I><N><T><M><S><K><I><R><G><Q><E><K><G><P><G><Y><P><Q><A><E><A><L><L><A><E><A><M><L><K><F><G><R><E><L><G><D><D... | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.<BOP> | Q99962 |
P43304 | GPDM_HUMAN | mtGPD | Homo | <M><A><F><Q><K><A><V><K><G><T><I><L><V><G><G><G><A><L><A><T><V><L><G><L><S><Q><F><A><H><Y><R><R><K><Q><M><N><L><A><Y><V><K><A><A><D><C><I><S><E><P><V><N><R><E><P><P><S><R><E><A><Q><L><L><T><L><Q><N><T><S><E><F><D><I><L><V><I><G><G><G><A><T><G><S><G><C><A><L><D><A><V><T><R><G><L><K><T><A><L><V><E><R><D><D><F><S><S><G><T... | Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.<BOP> | P43304 |
P43166 | CAH7_HUMAN | Carbonic anhydrase VII | Homo | <M><T><G><H><H><G><W><G><Y><G><Q><D><D><G><P><S><H><W><H><K><L><Y><P><I><A><Q><G><D><R><Q><S><P><I><N><I><I><S><S><Q><A><V><Y><S><P><S><L><Q><P><L><E><L><S><Y><E><A><C><M><S><L><S><I><T><N><N><G><H><S><V><Q><V><D><F><N><D><S><D><D><R><T><V><V><T><G><G><P><L><E><G><P><Y><R><L><K><Q><F><H><F><H><W><G><K><K><H><D><V><G><S... | Reversible hydration of carbon dioxide.<BOP> | P43166 |
Q6NV75 | GP153_HUMAN | G-protein coupled receptor PGR1 | Homo | <M><S><D><E><R><R><L><P><G><S><A><V><G><W><L><V><C><G><G><L><S><L><L><A><N><A><W><G><I><L><S><V><G><A><K><Q><K><K><W><K><P><L><E><F><L><L><C><T><L><A><A><T><H><M><L><N><V><A><V><P><I><A><T><Y><S><V><V><Q><L><R><R><Q><R><P><D><F><E><W><N><E><G><L><C><K><V><F><V><S><T><F><Y><T><L><T><L><A><T><C><F><S><V><T><S><L><S><Y><H... | Orphan receptor.<BOP> | Q6NV75 |
Q5VTH2 | FLTOP_HUMAN | Cilia- and flagella-associated protein 126 | Homo | <M><A><T><N><Y><S><A><N><Q><Y><E><K><A><F><S><S><K><Y><L><Q><N><W><S><P><T><K><P><T><K><E><S><I><S><S><H><E><G><Y><T><Q><I><I><A><N><D><R><G><H><L><L><P><S><V><P><R><S><K><A><N><P><W><G><S><F><M><G><T><W><Q><M><P><L><K><I><P><P><A><R><V><T><L><T><S><R><T><T><A><G><A><A><S><L><T><K><W><I><Q><K><N><P><D><L><L><K><A><S><N... | Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.<BOP> | Q5VTH2 |
Q7L0Y3 | TM10C_HUMAN | tRNA (guanine(9)-N(1))-methyltransferase | Homo | <M><A><A><F><L><K><M><S><V><S><V><N><F><F><R><P><F><T><R><F><L><V><P><F><T><L><H><R><K><R><N><N><L><T><I><L><Q><R><Y><M><S><S><K><I><P><A><V><T><Y><P><K><N><E><S><T><P><P><S><E><E><L><E><L><D><K><W><K><T><T><M><K><S><S><V><Q><E><E><C><V><S><T><I><S><S><S><K><D><E><D><P><L><A><A><T><R><E><F><I><E><M><W><R><L><L><G><R><E... | Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation . Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends . Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribo... | Q7L0Y3 |
Q7Z7J7 | LHPL4_HUMAN | Lipoma HMGIC fusion partner-like 4 protein | Homo | <M><L><P><S><Q><E><A><S><K><L><Y><H><E><H><Y><M><R><N><S><R><A><I><G><V><L><W><A><I><F><T><I><C><F><A><I><I><N><V><V><V><F><I><Q><P><Y><W><V><G><D><S><V><S><T><P><K><P><G><Y><F><G><L><F><H><Y><C><V><G><S><G><L><A><G><R><E><L><T><C><R><G><S><F><T><D><F><S><T><I><P><S><S><A><F><K><A><A><A><F><F><V><L><L><S><M><V><L><I><L... | Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs.<BOP> | Q7Z7J7 |
Q14651 | PLSI_HUMAN | Intestine-specific plastin | Homo | <M><E><N><S><T><T><T><I><S><R><E><E><L><E><E><L><Q><E><A><F><N><K><I><D><I><D><N><S><G><Y><V><S><D><Y><E><L><Q><D><L><F><K><E><A><S><L><P><L><P><G><Y><K><V><R><E><I><V><E><K><I><L><S><V><A><D><S><N><K><D><G><K><I><S><F><E><E><F><V><S><L><M><Q><E><L><K><S><K><D><I><S><K><T><F><R><K><I><I><N><K><R><E><G><I><T><A><I><G><G... | Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.<BOP> | Q14651 |
Q8NCP5 | ZBT44_HUMAN | Zinc finger protein 851 | Homo | <M><G><V><K><T><F><T><H><S><S><S><S><H><S><Q><E><M><L><G><K><L><N><M><L><R><N><D><G><H><F><C><D><I><T><I><R><V><Q><D><K><I><F><R><A><H><K><V><V><L><A><A><C><S><D><F><F><R><T><K><L><V><G><Q><A><E><D><E><N><K><N><V><L><D><L><H><H><V><T><V><T><G><F><I><P><L><L><E><Y><A><Y><T><A><T><L><S><I><N><T><E><N><I><I><D><V><L><A><A... | May be involved in transcriptional regulation.<BOP> | Q8NCP5 |
Q9BRY0 | S39A3_HUMAN | Zrt- and Irt-like protein 3 | Homo | <M><V><K><L><L><V><A><K><I><L><C><M><V><G><V><F><F><F><M><L><L><G><S><L><L><P><V><K><I><I><E><T><D><F><E><K><A><H><R><S><K><K><I><L><S><L><C><N><T><F><G><G><G><V><F><L><A><T><C><F><N><A><L><L><P><A><V><R><E><K><L><Q><K><V><L><S><L><G><H><I><S><T><D><Y><P><L><A><E><T><I><L><L><L><G><F><F><M><T><V><F><L><E><Q><L><I><L><T... | Acts as a zinc-influx transporter.<BOP> | Q9BRY0 |
Q9BY27 | DGC6L_HUMAN | DiGeorge syndrome critical region 6-like protein | Homo | <M><E><R><Y><A><A><A><L><E><E><V><A><D><G><A><R><Q><Q><E><R><H><Y><Q><L><L><S><A><L><Q><S><L><V><K><E><L><P><S><S><F><Q><Q><R><L><S><Y><T><T><L><S><D><L><A><L><A><L><L><D><G><T><V><F><E><I><V><Q><G><L><L><E><I><Q><H><L><T><E><K><S><L><Y><N><Q><R><L><R><L><Q><N><E><H><R><V><L><R><Q><A><L><R><Q><K><H><Q><E><A><Q><Q><A><C... | May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.<BOP> | Q9BY27 |
P20962 | PTMS_HUMAN | Parathymosin | Homo | <M><S><E><K><S><V><E><A><A><A><E><L><S><A><K><D><L><K><E><K><K><E><K><V><E><E><K><A><S><R><K><E><R><K><K><E><V><V><E><E><E><E><N><G><A><E><E><E><E><E><E><T><A><E><D><G><E><E><E><D><E><G><E><E><E><D><E><E><E><E><E><E><D><D><E><G><P><A><L><K><R><A><A><E><E><E><D><E><A><D><P><K><R><Q><K><T><E><N><G><A><S><A> | Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.<BOP> | P20962 |
Q8NGT9 | OR2A1_HUMAN | Olfactory receptor OR7-19 | Homo | <M><G><E><N><Q><T><M><V><T><E><F><L><L><L><G><F><L><L><G><P><R><I><Q><M><L><L><F><G><L><F><S><L><F><Y><I><F><T><L><L><G><N><G><A><I><L><G><L><I><S><L><D><S><R><L><H><T><P><M><Y><F><F><L><S><H><L><A><V><V><D><I><A><Y><T><R><N><T><V><P><Q><M><L><A><N><L><L><H><P><A><K><P><I><S><F><A><G><C><M><T><Q><T><F><L><C><L><S><F><G... | Odorant receptor.<BOP> | Q8NGT9 |
Q8WXI3 | ASB10_HUMAN | Ankyrin repeat and SOCS box protein 10 | Homo | <M><L><M><S><W><S><P><E><E><C><K><G><Q><G><E><P><L><D><D><R><H><P><L><C><A><R><L><V><E><K><P><S><R><G><S><E><E><H><L><K><S><G><P><G><P><I><V><T><R><T><A><S><G><P><A><L><A><F><W><Q><A><V><L><A><G><D><V><G><C><V><S><R><I><L><A><D><S><S><T><G><L><A><P><D><S><V><F><D><T><S><D><P><E><R><W><R><D><F><R><F><N><I><R><A><L><R><L... | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q8WXI3 |
Q8N726 | ARF_HUMAN | p14ARF | Homo | <M><V><R><R><F><L><V><T><L><R><I><R><R><A><C><G><P><P><R><V><R><V><F><V><V><H><I><P><R><L><T><G><E><W><A><A><P><G><A><P><A><A><V><A><L><V><L><M><L><L><R><S><Q><R><L><G><Q><Q><P><L><P><R><R><P><G><H><D><D><G><Q><R><P><S><G><G><A><A><A><A><P><R><R><G><A><Q><L><R><R><P><R><H><S><H><P><T><R><A><R><R><C><P><G><G><L><P><G><H... | May be involved in regulation of autophagy and caspase-independent cell death; the short-lived mitochondrial isoform is stabilized by C1QBP.<BOP> | Q8N726 |
Q13477 | MADCA_HUMAN | Mucosal addressin cell adhesion molecule 1 | Homo | <M><D><F><G><L><A><L><L><L><A><G><L><L><G><L><L><L><G><Q><S><L><Q><V><K><P><L><Q><V><E><P><P><E><P><V><V><A><V><A><L><G><A><S><R><Q><L><T><C><R><L><A><C><A><D><R><G><A><S><V><Q><W><R><G><L><D><T><S><L><G><A><V><Q><S><D><T><G><R><S><V><L><T><V><R><N><A><S><L><S><A><A><G><T><R><V><C><V><G><S><C><G><G><R><T><F><Q><H><T><V... | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the m... | Q13477 |
Q8WTP8 | AEN_HUMAN | Interferon-stimulated 20 kDa exonuclease-like 1 | Homo | <M><V><P><R><E><A><P><E><S><A><Q><C><L><C><P><S><L><T><I><P><N><A><K><D><V><L><R><K><R><H><K><R><R><S><R><Q><H><Q><R><F><M><A><R><K><A><L><L><Q><E><Q><G><L><L><S><M><P><P><E><P><G><S><S><P><L><P><T><P><F><G><A><A><T><A><T><E><A><A><S><S><G><K><Q><C><L><R><A><G><S><G><S><A><P><C><S><R><R><P><A><P><G><K><A><S><G><P><L><P... | Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.<BOP> | Q8WTP8 |
Q9Y2D9 | ZN652_HUMAN | Zinc finger protein 652 | Homo | <M><S><H><T><A><S><S><C><Q><E><L><V><E><N><C><A><V><H><V><A><G><M><A><Q><E><D><S><R><R><G><Q><V><P><S><S><F><Y><H><G><A><N><Q><E><L><D><L><S><T><K><V><Y><K><R><E><S><G><S><P><Y><S><V><L><V><D><T><K><M><S><K><P><H><L><H><E><T><E><E><Q><P><Y><F><R><E><T><R><A><V><S><D><V><H><A><V><K><E><D><R><E><N><S><D><D><T><E><E><E><E... | Functions as a transcriptional repressor.<BOP> | Q9Y2D9 |
Q7Z3T1 | OR2W3_HUMAN | Olfactory receptor OR1-49 | Homo | <M><D><G><T><N><G><S><T><Q><T><H><F><I><L><L><G><F><S><D><R><P><H><L><E><R><I><L><F><V><V><I><L><I><A><Y><L><L><T><L><V><G><N><T><T><I><I><L><V><S><R><L><D><P><H><L><H><T><P><M><Y><F><F><L><A><H><L><S><F><L><D><L><S><F><T><T><S><S><I><P><Q><L><L><Y><N><L><N><G><C><D><K><T><I><S><Y><M><G><C><A><I><Q><L><F><L><F><L><G><L... | Odorant receptor.<BOP> | Q7Z3T1 |
Q5VUJ5 | AGAP7_HUMAN | Centaurin-gamma-like family member 4 | Homo | <M><G><N><I><L><T><C><R><V><H><P><S><V><S><L><E><F><D><Q><Q><Q><G><S><V><C><P><S><E><S><E><I><Y><E><A><G><A><E><D><R><M><A><G><A><P><M><A><A><A><V><Q><P><A><E><V><T><V><E><V><G><E><D><L><H><M><H><H><V><R><D><R><E><M><P><E><A><L><E><F><N><P><S><A><N><P><E><A><S><T><I><F><Q><R><N><S><Q><T><D><V><V><E><I><R><R><S><N><C><T... | Putative GTPase-activating protein.<BOP> | Q5VUJ5 |
Q86YJ7 | AN13B_HUMAN | Ankyrin repeat domain-containing protein 13B | Homo | <M><I><P><A><N><A><S><A><R><K><G><P><E><G><K><Y><P><L><H><Y><L><V><W><H><N><R><H><R><E><L><E><K><E><V><R><A><G><Q><V><D><I><E><Q><L><D><P><R><G><R><T><P><L><H><L><A><T><T><L><G><H><L><E><C><A><R><V><L><L><A><H><G><A><D><V><G><R><E><N><R><S><G><W><T><V><L><Q><E><A><V><S><T><R><D><L><E><L><V><Q><L><V><L><R><Y><R><D><Y><Q... | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.<BOP> | Q86YJ7 |
O95292 | VAPB_HUMAN | Vesicle-associated membrane protein-associated protein B/C | Homo | <M><A><K><V><E><Q><V><L><S><L><E><P><Q><H><E><L><K><F><R><G><P><F><T><D><V><V><T><T><N><L><K><L><G><N><P><T><D><R><N><V><C><F><K><V><K><T><T><A><P><R><R><Y><C><V><R><P><N><S><G><I><I><D><A><G><A><S><I><N><V><S><V><M><L><Q><P><F><D><Y><D><P><N><E><K><S><K><H><K><F><M><V><Q><S><M><F><A><P><T><D><T><S><D><M><E><A><V><W><K... | Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<BOP> | O95292 |
Q9H467 | CUED2_HUMAN | CUE domain-containing protein 2 | Homo | <M><E><L><E><R><I><V><S><A><A><L><L><A><F><V><Q><T><H><L><P><E><A><D><L><S><G><L><D><E><V><I><F><S><Y><V><L><G><V><L><E><D><L><G><P><S><G><P><S><E><E><N><F><D><M><E><A><F><T><E><M><M><E><A><Y><V><P><G><F><A><H><I><P><R><G><T><I><G><D><M><M><Q><K><L><S><G><Q><L><S><D><A><R><N><K><E><N><L><Q><P><Q><S><S><G><V><Q><G><Q><V... | Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.<BOP> | Q9H467 |
Q9Y6Z7 | COL10_HUMAN | Collectin-34 | Homo | <M><N><G><F><A><S><L><L><R><R><N><Q><F><I><L><L><V><L><F><L><L><Q><I><Q><S><L><G><L><D><I><D><S><R><P><T><A><E><V><C><A><T><H><T><I><S><P><G><P><K><G><D><D><G><E><K><G><D><P><G><E><E><G><K><H><G><K><V><G><R><M><G><P><K><G><I><K><G><E><L><G><D><M><G><D><Q><G><N><I><G><K><T><G><P><I><G><K><K><G><D><K><G><E><K><G><L><L><G... | Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine . Acts as a chemoattractant, probably involved in the regulation of cell migration .<BOP> | Q9Y6Z7 |
Q30KR1 | DB109_HUMAN | Defensin, beta 109B | Homo | <M><R><L><H><L><L><L><L><I><L><L><L><F><S><I><L><L><S><P><V><R><G><G><L><G><P><A><E><G><H><C><L><N><L><F><G><V><C><R><T><D><V><C><N><I><V><E><D><Q><I><G><A><C><R><R><R><M><K><C><C><R><A><W><W><I><L><M><P><I><P><T><P><L><I><M><S><D><Y><Q><E><P><L><K><P><N><L><K> | Has antibacterial activity.<BOP> | Q30KR1 |
A0A0C4DH39 | HV158_HUMAN | Immunoglobulin heavy variable 1-58 | Homo | <M><D><W><I><W><R><I><L><F><L><V><G><A><A><T><G><A><H><S><Q><M><Q><L><V><Q><S><G><P><E><V><K><K><P><G><T><S><V><K><V><S><C><K><A><S><G><F><T><F><T><S><S><A><V><Q><W><V><R><Q><A><R><G><Q><R><L><E><W><I><G><W><I><V><V><G><S><G><N><T><N><Y><A><Q><K><F><Q><E><R><V><T><I><T><R><D><M><S><T><S><T><A><Y><M><E><L><S><S><L><R><S... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0C4DH39 |
P51523 | ZNF84_HUMAN | Zinc finger protein HPF2 | Homo | <M><T><M><L><Q><E><S><F><S><F><D><D><L><S><V><D><F><T><Q><K><E><W><Q><L><L><D><P><S><Q><K><N><L><Y><K><D><V><M><L><E><N><Y><S><S><L><V><S><L><G><Y><E><V><M><K><P><D><V><I><F><K><L><E><Q><G><E><E><P><W><V><G><D><G><E><I><P><S><S><D><S><P><E><V><W><K><V><D><G><N><M><M><W><H><Q><D><N><Q><D><K><L><K><I><I><K><R><G><H><E><C... | May be involved in transcriptional regulation.<BOP> | P51523 |
P69905 | HBA_HUMAN | Hemopressin | Homo | <M><V><L><S><P><A><D><K><T><N><V><K><A><A><W><G><K><V><G><A><H><A><G><E><Y><G><A><E><A><L><E><R><M><F><L><S><F><P><T><T><K><T><Y><F><P><H><F><D><L><S><H><G><S><A><Q><V><K><G><H><G><K><K><V><A><D><A><L><T><N><A><V><A><H><V><D><D><M><P><N><A><L><S><A><L><S><D><L><H><A><H><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L... | Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 . Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling .<BOP> | P69905 |
A0A0B4J1X8 | HV343_HUMAN | Immunoglobulin heavy variable 3-43 | Homo | <M><E><F><G><L><S><W><V><F><L><V><A><I><L><K><G><V><Q><C><E><V><Q><L><V><E><S><G><G><V><V><V><Q><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><D><D><Y><T><M><H><W><V><R><Q><A><P><G><K><G><L><E><W><V><S><L><I><S><W><D><G><G><S><T><Y><Y><A><D><S><V><K><G><R><F><T><I><S><R><D><N><S><K><N><S><L><Y><L><Q><M><N><S><L><R><T... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0B4J1X8 |
P33908 | MA1A1_HUMAN | Processing alpha-1,2-mannosidase IA | Homo | <M><P><V><G><G><L><L><P><L><F><S><S><P><A><G><G><V><L><G><G><G><L><G><G><G><G><G><R><K><G><S><G><P><A><A><L><R><L><T><E><K><F><V><L><L><L><V><F><S><A><F><I><T><L><C><F><G><A><I><F><F><L><P><D><S><S><K><L><L><S><G><V><L><F><H><S><S><P><A><L><Q><P><A><A><D><H><K><P><G><P><G><A><R><A><E><D><A><A><E><G><R><A><R><R><R><E><E... | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).<BOP> | P33908 |
P26992 | CNTFR_HUMAN | Ciliary neurotrophic factor receptor subunit alpha | Homo | <M><A><A><P><V><P><W><A><C><C><A><V><L><A><A><A><A><A><V><V><Y><A><Q><R><H><S><P><Q><E><A><P><H><V><Q><Y><E><R><L><G><S><D><V><T><L><P><C><G><T><A><N><W><D><A><A><V><T><W><R><V><N><G><T><D><L><A><P><D><L><L><N><G><S><Q><L><V><L><H><G><L><E><L><G><H><S><G><L><Y><A><C><F><H><R><D><S><W><H><L><R><H><Q><V><L><L><H><V><G><L... | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1 . Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1 .<BOP> | P26992 |
A0A5A6 | TVBK3_HUMAN | T cell receptor beta variable 11-3 | Homo | <M><G><T><R><L><L><C><W><V><A><F><C><L><L><V><E><E><L><I><E><A><G><V><V><Q><S><P><R><Y><K><I><I><E><K><K><Q><P><V><A><F><W><C><N><P><I><S><G><H><N><T><L><Y><W><Y><L><Q><N><L><G><Q><G><P><E><L><L><I><R><Y><E><N><E><E><A><V><D><D><S><Q><L><P><K><D><R><F><S><A><E><R><L><K><G><V><D><S><T><L><K><I><Q><P><A><E><L><G><D><S><A... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A5A6 |
O96017 | CHK2_HUMAN | Checkpoint kinase 2 | Homo | <M><S><R><E><S><D><V><E><A><Q><Q><S><H><G><S><S><A><C><S><Q><P><H><G><S><V><T><Q><S><Q><G><S><S><S><Q><S><Q><G><I><S><S><S><S><T><S><T><M><P><N><S><S><Q><S><S><H><S><S><S><G><T><L><S><S><L><E><T><V><S><T><Q><E><L><Y><S><I><P><E><D><Q><E><P><E><D><Q><E><P><E><E><P><T><P><A><P><W><A><R><L><W><A><L><Q><D><G><F><A><N><L><E... | (Microbial infection) Phosphorylates herpes simplex virus 1/HHV-1 protein ICP0 and thus activates its SUMO-targeted ubiquitin ligase activity.<BOP> | O96017 |
Q9H2I8 | LRMDA_HUMAN | Leucine-rich melanocyte differentiation-associated protein | Homo | <M><E><K><Y><L><S><L><S><G><N><H><S><S><N><K><R><S><L><E><G><L><S><A><F><R><S><L><E><E><L><I><L><D><N><N><Q><L><G><D><D><L><V><L><P><G><L><P><R><L><H><T><L><T><L><N><K><N><R><I><T><D><L><E><N><L><L><D><H><L><A><E><V><T><P><A><L><E><Y><L><S><L><L><G><N><V><A><C><P><N><E><L><V><S><L><E><K><D><E><E><D><Y><K><R><Y><R><C><F... | Required for melanocyte differentiation.<BOP> | Q9H2I8 |
Q8NBR0 | P5I13_HUMAN | Damage-stimulated cytoplasmic protein 1 | Homo | <M><A><P><P><P><P><S><P><Q><L><L><L><L><A><A><L><A><R><L><L><G><P><S><E><V><M><A><G><P><A><E><E><A><G><A><H><C><P><E><S><L><W><P><L><P><P><Q><V><S><P><R><V><T><Y><T><R><V><S><P><G><Q><A><E><D><V><T><F><L><Y><H><P><C><A><H><P><W><L><K><L><Q><L><A><L><L><A><Y><A><C><M><A><N><P><S><L><T><P><D><F><S><L><T><Q><D><R><P><L><V... | May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed.<BOP> | Q8NBR0 |
P52429 | DGKE_HUMAN | Diglyceride kinase epsilon | Homo | <M><E><A><E><R><R><P><A><P><G><S><P><S><E><G><L><F><A><D><G><H><L><I><L><W><T><L><C><S><V><L><L><P><V><F><I><T><F><W><C><S><L><Q><R><S><R><R><Q><L><H><R><R><D><I><F><R><K><S><K><H><G><W><R><D><T><D><L><F><S><Q><P><T><Y><C><C><V><C><A><Q><H><I><L><Q><G><A><F><C><D><C><C><G><L><R><V><D><E><G><C><L><R><K><A><D><K><R><F><Q... | Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and oppo... | P52429 |
A6NHG9 | O5H14_HUMAN | Olfactory receptor 5H14 | Homo | <M><E><E><E><N><A><T><L><L><T><E><F><V><L><T><G><F><L><Y><Q><P><Q><W><K><I><P><L><F><L><A><F><L><V><I><Y><L><I><T><I><M><G><N><L><G><L><I><A><V><I><W><K><D><P><H><L><H><I><P><M><Y><L><L><L><G><N><L><A><F><V><D><A><L><L><S><S><S><V><T><L><K><M><L><I><N><F><L><A><K><S><K><M><I><S><L><S><E><C><K><I><Q><L><F><S><F><A><I><S... | Odorant receptor.<BOP> | A6NHG9 |
Q96PM9 | Z385A_HUMAN | Retinal zinc finger protein | Homo | <M><I><L><G><S><L><S><R><A><G><P><L><P><L><L><R><Q><P><P><I><M><Q><P><P><L><D><L><K><Q><I><L><P><F><P><L><E><P><A><P><T><L><G><L><F><S><N><Y><S><T><M><D><P><V><Q><K><A><V><L><S><H><T><F><G><G><P><L><L><K><T><K><R><P><V><I><S><C><N><I><C><Q><I><R><F><N><S><Q><S><Q><A><E><A><H><Y><K><G><N><R><H><A><R><R><V><K><G><I><E><A... | RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, b... | Q96PM9 |
P47871 | GLR_HUMAN | Glucagon receptor | Homo | <M><P><P><C><Q><P><Q><R><P><L><L><L><L><L><L><L><L><A><C><Q><P><Q><V><P><S><A><Q><V><M><D><F><L><F><E><K><W><K><L><Y><G><D><Q><C><H><H><N><L><S><L><L><P><P><P><T><E><L><V><C><N><R><T><F><D><K><Y><S><C><W><P><D><T><P><A><N><T><T><A><N><I><S><C><P><W><Y><L><P><W><H><H><K><V><Q><H><R><F><V><F><K><R><C><G><P><D><G><Q><W><V... | G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes... | P47871 |
Q9NVA4 | T184C_HUMAN | Transmembrane protein 34 | Homo | <M><P><C><T><C><T><W><R><N><W><R><Q><W><I><R><P><L><V><A><V><I><Y><L><V><S><I><V><V><A><V><P><L><C><V><W><E><L><Q><K><L><E><V><G><I><H><T><K><A><W><F><I><A><G><I><F><L><L><L><T><I><P><I><S><L><W><V><I><L><Q><H><L><V><H><Y><T><Q><P><E><L><Q><K><P><I><I><R><I><L><W><M><V><P><I><Y><S><L><D><S><W><I><A><L><K><Y><P><G><I><A... | Possible tumor suppressor which may play a role in cell growth.<BOP> | Q9NVA4 |
Q9H511 | KLH31_HUMAN | Kelch-like protein KLHL | Homo | <M><A><P><K><K><K><I><V><K><K><N><K><G><D><I><N><E><M><T><I><I><V><E><D><S><P><L><N><K><L><N><A><L><N><G><L><L><E><G><G><N><G><L><S><C><I><S><S><E><L><T><D><A><S><Y><G><P><N><L><L><E><G><L><S><K><M><R><Q><E><N><F><L><C><D><L><V><I><G><T><K><T><K><S><F><D><V><H><K><S><V><M><A><S><C><S><E><Y><F><Y><N><I><L><K><K><D><P><S... | Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).<BOP> | Q9H511 |
P01906 | DQA2_HUMAN | MHC class II DQA2 | Homo | <M><I><L><N><K><A><L><L><L><G><A><L><A><L><T><A><V><M><S><P><C><G><G><E><D><I><V><A><D><H><V><A><S><Y><G><V><N><F><Y><Q><S><H><G><P><S><G><Q><Y><T><H><E><F><D><G><D><E><E><F><Y><V><D><L><E><T><K><E><T><V><W><Q><L><P><M><F><S><K><F><I><S><F><D><P><Q><S><A><L><R><N><M><A><V><G><K><H><T><L><E><F><M><M><R><Q><S><N><S><T><A... | Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by deg... | P01906 |
A8MTA8 | F166B_HUMAN | Protein FAM166B | Homo | <M><A><V><A><S><T><F><I><P><G><L><N><P><Q><N><P><H><Y><I><P><G><Y><T><G><H><C><P><L><L><R><F><S><V><G><Q><T><Y><G><Q><V><T><G><Q><L><L><R><G><P><P><G><L><A><W><P><P><V><H><R><T><L><L><P><P><I><R><P><P><R><S><P><E><V><P><R><E><S><L><P><V><R><R><G><Q><E><R><L><S><S><S><M><I><P><G><Y><T><G><F><V><P><R><A><Q><F><I><F><A><K... | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.<BOP> | A8MTA8 |
Q9NRK6 | ABCBA_HUMAN | Mitochondrial ATP-binding cassette 2 | Homo | <M><R><G><P><P><A><W><P><L><R><L><L><E><P><P><S><P><A><E><P><G><R><L><L><P><V><A><C><V><W><A><A><A><S><R><V><P><G><S><L><S><P><F><T><G><L><R><P><A><R><L><W><G><A><G><P><A><L><L><W><G><V><G><A><A><R><R><W><R><S><G><C><R><G><G><G><P><G><A><S><R><G><V><L><G><L><A><R><L><L><G><L><W><A><R><G><P><G><S><C><R><C><G><A><F><A><G... | Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner . May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria . Plays a role... | Q9NRK6 |
Q8WWI5 | CTL1_HUMAN | Solute carrier family 44 member 1 | Homo | <M><G><C><C><S><S><A><S><S><A><A><Q><S><S><K><R><E><W><K><P><L><E><D><R><S><C><T><D><I><P><W><L><L><L><F><I><L><F><C><I><G><M><G><F><I><C><G><F><S><I><A><T><G><A><A><A><R><L><V><S><G><Y><D><S><Y><G><N><I><C><G><Q><K><N><T><K><L><E><A><I><P><N><S><G><M><D><H><T><Q><R><K><Y><V><F><F><L><D><P><C><N><L><D><L><I><N><R><K><I... | Choline transporter. Involved in membrane synthesis and myelin production.<BOP> | Q8WWI5 |
Q9NQE9 | HINT3_HUMAN | Histidine triad nucleotide-binding protein 3 | Homo | <M><A><E><E><Q><V><N><R><S><A><G><L><A><P><D><C><E><A><S><A><T><A><E><T><T><V><S><S><V><G><T><C><E><A><A><G><K><S><P><E><P><K><D><Y><D><S><T><C><V><F><C><R><I><A><G><R><Q><D><P><G><T><E><L><L><H><C><E><N><E><D><L><I><C><F><K><D><I><K><P><A><A><T><H><H><Y><L><V><V><P><K><K><H><I><G><N><C><R><T><L><R><K><D><Q><V><E><L><V... | Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 . Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase . Hydrolyzes... | Q9NQE9 |
P31146 | COR1A_HUMAN | Tryptophan aspartate-containing coat protein | Homo | <M><S><R><Q><V><V><R><S><S><K><F><R><H><V><F><G><Q><P><A><K><A><D><Q><C><Y><E><D><V><R><V><S><Q><T><T><W><D><S><G><F><C><A><V><N><P><K><F><V><A><L><I><C><E><A><S><G><G><G><A><F><L><V><L><P><L><G><K><T><G><R><V><D><K><N><A><P><T><V><C><G><H><T><A><P><V><L><D><I><A><W><C><P><H><N><D><N><V><I><A><S><G><S><E><D><C><T><V><M... | May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion b... | P31146 |
A0A286YF77 | SCGR6_HUMAN | Keratin-associated protein 28-6 | Homo | <M><G><C><C><G><C><G><G><C><G><G><G><C><G><G><C><G><G><G><C><S><G><G><C><G><G><G><C><G><G><G><C><G><S><C><T><T><C><R><C><Y><R><V><G><C><C><S><S><C><C><P><C><C><R><G><C><C><G><G><C><C><S><T><P><V><I><C><C><C><R><R><T><C><H><S><C><G><C><G><C><G><C><G><K><G><C><C><Q><Q><K><G><C><C><Q><Q><K><G><C><C><K><K><Q><C><C><C> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | A0A286YF77 |
O75312 | ZPR1_HUMAN | Zinc finger protein 259 | Homo | <M><A><A><S><G><A><V><E><P><G><P><P><G><A><A><V><A><P><S><P><A><P><A><P><P><P><A><P><D><H><L><F><R><P><I><S><A><E><D><E><E><Q><Q><P><T><E><I><E><S><L><C><M><N><C><Y><C><N><G><M><T><R><L><L><L><T><K><I><P><F><F><R><E><I><I><V><S><S><F><S><C><E><H><C><G><W><N><N><T><E><I><Q><S><A><G><R><I><Q><D><Q><G><V><R><Y><T><L><S><V... | Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. It is involved in the positive regulation of cell cycle progression . Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Caja... | O75312 |
Q5FVE4 | ACBG2_HUMAN | PRTD-NY3 | Homo | <M><T><G><T><P><K><T><Q><E><G><A><K><D><L><E><V><D><M><N><K><T><E><V><T><P><R><L><W><T><T><C><R><D><G><E><V><L><L><R><L><S><K><H><G><P><G><H><E><T><P><M><T><I><P><E><F><F><R><E><S><V><N><R><F><G><T><Y><P><A><L><A><S><K><N><G><K><K><W><E><I><L><N><F><N><Q><Y><Y><E><A><C><R><K><A><A><K><S><L><I><K><L><G><L><E><R><F><H><G... | Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids . Has increased ability to activate oleic and... | Q5FVE4 |
P13861 | KAP2_HUMAN | cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo | <M><S><H><I><Q><I><P><P><G><L><T><E><L><L><Q><G><Y><T><V><E><V><L><R><Q><Q><P><P><D><L><V><E><F><A><V><E><Y><F><T><R><L><R><E><A><R><A><P><A><S><V><L><P><A><A><T><P><R><Q><S><L><G><H><P><P><P><E><P><G><P><D><R><V><A><D><A><K><G><D><S><E><S><E><E><D><E><D><L><E><V><P><V><P><S><R><F><N><R><R><V><S><V><C><A><E><T><Y><N><P... | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.<BOP> | P13861 |
A0A0B4J249 | TVA5_HUMAN | T cell receptor alpha variable 5 | Homo | <M><K><T><F><A><G><F><S><F><L><F><L><W><L><Q><L><D><C><M><S><R><G><E><D><V><E><Q><S><L><F><L><S><V><R><E><G><D><S><S><V><I><N><C><T><Y><T><D><S><S><S><T><Y><L><Y><W><Y><K><Q><E><P><G><A><G><L><Q><L><L><T><Y><I><F><S><N><M><D><M><K><Q><D><Q><R><L><T><V><L><L><N><K><K><D><K><H><L><S><L><R><I><A><D><T><Q><T><G><D><S><A><I... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A0B4J249 |
Q96JP0 | FEM1C_HUMAN | FEM1-gamma | Homo | <M><D><L><K><T><A><V><F><N><A><A><R><D><G><K><L><R><L><L><T><K><L><L><A><S><K><S><K><E><E><V><S><S><L><I><S><E><K><T><N><G><A><T><P><L><L><M><A><A><R><Y><G><H><L><D><M><V><E><F><L><L><E><Q><C><S><A><S><I><E><V><G><G><S><V><N><F><D><G><E><T><I><E><G><A><P><P><L><W><A><A><S><A><A><G><H><L><K><V><V><Q><S><L><L><N><H><G><A... | Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation . The C-degron recognized by the DesCEND pat... | Q96JP0 |
Q5VV42 | CDKAL_HUMAN | tRNA-t(6)A37 methylthiotransferase | Homo | <M><P><S><A><S><C><D><T><L><L><D><D><I><E><D><I><V><S><Q><E><D><S><K><P><Q><D><R><H><F><V><R><K><D><V><V><P><K><V><R><R><R><N><T><Q><K><Y><L><Q><E><E><E><N><S><P><P><S><D><S><T><I><P><G><I><Q><K><I><W><I><R><T><W><G><C><S><H><N><N><S><D><G><E><Y><M><A><G><Q><L><A><A><Y><G><Y><K><I><T><E><N><A><S><D><A><D><L><W><L><L><N... | Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.<BOP> | Q5VV42 |
Q96AP7 | ESAM_HUMAN | Endothelial cell-selective adhesion molecule | Homo | <M><I><S><L><P><G><P><L><V><T><N><L><L><R><F><L><F><L><G><L><S><A><L><A><P><P><S><R><A><Q><L><Q><L><H><L><P><A><N><R><L><Q><A><V><E><G><G><E><V><V><L><P><A><W><Y><T><L><H><G><E><V><S><S><S><Q><P><W><E><V><P><F><V><M><W><F><F><K><Q><K><E><K><E><D><Q><V><L><S><Y><I><N><G><V><T><T><S><K><P><G><V><S><L><V><Y><S><M><P><S><R... | Can mediate aggregation most likely through a homophilic molecular interaction.<BOP> | Q96AP7 |
Q8TBJ4 | PLPR1_HUMAN | Plasticity-related gene 3 protein | Homo | <M><A><V><G><N><N><T><Q><R><S><Y><S><I><I><P><C><F><I><F><V><E><L><V><I><M><A><G><T><V><L><L><A><Y><Y><F><E><C><T><D><T><F><Q><V><H><I><Q><G><F><F><C><Q><D><G><D><L><M><K><P><Y><P><G><T><E><E><E><S><F><I><T><P><L><V><L><Y><C><V><L><A><A><T><P><T><A><I><I><F><I><G><E><I><S><M><Y><F><I><K><S><T><R><E><S><L><I><A><Q><E><K... | May play a role in neurite outgrowth and neurogenesis.<BOP> | Q8TBJ4 |
P57738 | TCTA_HUMAN | T-cell leukemia translocation-associated gene protein | Homo | <M><A><E><S><W><S><G><Q><A><L><Q><A><L><P><A><T><V><L><G><A><L><G><S><E><F><L><R><E><W><E><A><Q><D><M><R><V><T><L><F><K><L><L><L><L><W><L><V><L><S><L><L><G><I><Q><L><A><W><G><F><Y><G><N><T><V><T><G><L><Y><H><R><P><G><L><G><G><Q><N><G><S><T><P><D><G><S><T><H><F><P><S><W><E><M><A><A><N><E><P><L><K><T><H><R><E> | May be required for cellular fusion during osteoclastogenesis.<BOP> | P57738 |
Q9NY37 | ASIC5_HUMAN | Human intestine Na(+) channel | Homo | <M><E><Q><T><E><K><S><K><V><Y><A><E><N><G><L><L><E><K><I><K><L><C><L><S><K><K><P><L><P><S><P><T><E><R><K><K><F><D><H><D><F><A><I><S><T><S><F><H><G><I><H><N><I><V><Q><N><R><S><K><I><R><R><V><L><W><L><V><V><V><L><G><S><V><S><L><V><T><W><Q><I><Y><I><R><L><L><N><Y><F><T><W><P><T><T><T><S><I><E><V><Q><Y><V><E><K><M><E><F><P... | Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.<BOP> | Q9NY37 |
Q8N6I1 | EID2_HUMAN | EID-1-like inhibitor of differentiation 2 | Homo | <M><S><K><L><P><A><D><S><S><V><P><Q><T><G><A><A><N><G><D><R><D><V><P><Q><A><E><V><G><R><G><R><R><E><P><A><P><A><Q><P><E><E><A><G><E><G><A><M><A><A><A><R><G><G><P><V><P><A><A><R><E><G><R><M><A><A><A><R><A><A><P><A><A><A><A><R><G><A><P><V><A><A><A><A><L><A><R><A><A><A><A><G><R><E><S><P><A><A><A><A><A><R><E><A><R><M><A><E... | Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-i... | Q8N6I1 |
Q7RTS3 | PTF1A_HUMAN | p48 DNA-binding subunit of transcription factor PTF1 | Homo | <M><D><A><V><L><L><E><H><F><P><G><G><L><D><A><F><P><S><S><Y><F><D><E><D><D><F><F><T><D><Q><S><S><R><D><P><L><E><D><G><D><E><L><L><A><D><E><Q><A><E><V><E><F><L><S><H><Q><L><H><E><Y><C><Y><R><D><G><A><C><L><L><L><Q><P><A><P><P><A><A><P><L><A><L><A><P><P><S><S><G><G><L><G><E><P><D><D><G><G><G><G><G><Y><C><C><E><T><G><A><P... | Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesi... | Q7RTS3 |
Q9UDX4 | S14L3_HUMAN | Tocopherol-associated protein 2 | Homo | <M><S><G><R><V><G><D><L><S><P><K><Q><A><E><T><L><A><K><F><R><E><N><V><Q><D><V><L><P><A><L><P><N><P><D><D><Y><F><L><L><R><W><L><R><A><R><N><F><D><L><Q><K><S><E><A><L><L><R><K><Y><M><E><F><R><K><T><M><D><I><D><H><I><L><D><W><Q><P><P><E><V><I><Q><K><Y><M><P><G><G><L><C><G><Y><D><R><D><G><C><P><V><W><Y><D><I><I><G><P><L><D... | Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.<BOP> | Q9UDX4 |
O43869 | OR2T1_HUMAN | Olfactory receptor OR1-61 | Homo | <M><W><Q><E><Y><Y><F><L><N><V><F><F><P><L><L><K><V><C><C><L><T><I><N><S><H><V><V><I><L><L><P><W><E><C><Y><H><L><I><W><K><I><L><P><Y><I><G><T><T><V><G><S><M><E><E><Y><N><T><S><S><T><D><F><T><F><M><G><L><F><N><R><K><E><T><S><G><L><I><F><A><I><I><S><I><I><F><F><T><A><L><M><A><N><G><V><M><I><F><L><I><Q><T><D><L><R><L><H><T... | Odorant receptor.<BOP> | O43869 |
O15551 | CLD3_HUMAN | Rat ventral prostate.1 protein homolog | Homo | <M><S><M><G><L><E><I><T><G><T><A><L><A><V><L><G><W><L><G><T><I><V><C><C><A><L><P><M><W><R><V><S><A><F><I><G><S><N><I><I><T><S><Q><N><I><W><E><G><L><W><M><N><C><V><V><Q><S><T><G><Q><M><Q><C><K><V><Y><D><S><L><L><A><L><P><Q><D><L><Q><A><A><R><A><L><I><V><V><A><I><L><L><A><A><F><G><L><L><V><A><L><V><G><A><Q><C><T><N><C><V... | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<BOP> | O15551 |
Q8NAT1 | PMGT2_HUMAN | Glycosyltransferase-like domain-containing protein 2 | Homo | <M><H><L><S><A><V><F><N><A><L><L><V><S><V><L><A><A><V><L><W><K><H><V><R><L><R><E><H><A><A><T><L><E><E><E><L><A><L><S><R><Q><A><T><E><P><A><P><A><L><R><I><D><Y><P><K><A><L><Q><I><L><M><E><G><G><T><H><M><V><C><T><G><R><T><H><T><D><R><I><C><R><F><K><W><L><C><Y><S><N><E><A><E><E><F><I><F><F><H><G><N><T><S><V><M><L><P><N><L... | O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosam... | Q8NAT1 |
P20783 | NTF3_HUMAN | Neurotrophic factor | Homo | <M><S><I><L><F><Y><V><I><F><L><A><Y><L><R><G><I><Q><G><N><N><M><D><Q><R><S><L><P><E><D><S><L><N><S><L><I><I><K><L><I><Q><A><D><I><L><K><N><K><L><S><K><Q><M><V><D><V><K><E><N><Y><Q><S><T><L><P><K><A><E><A><P><R><E><P><E><R><G><G><P><A><K><S><A><F><Q><P><V><I><A><M><D><T><E><L><L><R><Q><Q><R><R><Y><N><S><P><R><V><L><L><S... | Seems to promote the survival of visceral and proprioceptive sensory neurons.<BOP> | P20783 |
Q13231 | CHIT1_HUMAN | Chitinase-1 | Homo | <M><V><R><S><V><A><W><A><G><F><M><V><L><L><M><I><P><W><G><S><A><A><K><L><V><C><Y><F><T><N><W><A><Q><Y><R><Q><G><E><A><R><F><L><P><K><D><L><D><P><S><L><C><T><H><L><I><Y><A><F><A><G><M><T><N><H><Q><L><S><T><T><E><W><N><D><E><T><L><Y><Q><E><F><N><G><L><K><K><M><N><P><K><L><K><T><L><L><A><I><G><G><W><N><F><G><T><Q><K><F><T... | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.<BOP> | Q13231 |
Q9NVF7 | FBX28_HUMAN | F-box only protein 28 | Homo | <M><A><A><A><A><E><E><R><M><A><E><E><G><G><G><G><Q><G><D><G><G><S><S><L><A><S><G><S><T><Q><R><Q><P><P><P><P><A><P><Q><H><P><Q><P><G><S><Q><A><L><P><A><P><A><L><A><P><D><Q><L><P><Q><N><N><T><L><V><A><L><P><I><V><A><I><E><N><I><L><S><F><M><S><Y><D><E><I><S><Q><L><R><L><V><C><K><R><M><D><L><V><C><Q><R><M><L><N><Q><G><F><L... | Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.<BOP> | Q9NVF7 |
Q96K19 | RN170_HUMAN | RING-type E3 ubiquitin transferase RNF170 | Homo | <M><A><K><Y><Q><G><E><V><Q><S><L><K><L><D><D><D><S><V><I><E><G><V><S><D><Q><V><L><V><A><V><V><V><S><F><A><L><I><A><T><L><V><Y><A><L><F><R><N><V><H><Q><N><I><H><P><E><N><Q><E><L><V><R><V><L><R><E><Q><L><Q><T><E><Q><D><A><P><A><A><T><R><Q><Q><F><Y><T><D><M><Y><C><P><I><C><L><H><Q><A><S><F><P><V><E><T><N><C><G><H><L><F><C... | E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.<BOP> | Q96K19 |
Q02383 | SEMG2_HUMAN | Semenogelin II | Homo | <M><K><S><I><I><L><F><V><L><S><L><L><L><I><L><E><K><Q><A><A><V><M><G><Q><K><G><G><S><K><G><Q><L><P><S><G><S><S><Q><F><P><H><G><Q><K><G><Q><H><Y><F><G><Q><K><D><Q><Q><H><T><K><S><K><G><S><F><S><I><Q><H><T><Y><H><V><D><I><N><D><H><D><W><T><R><K><S><Q><Q><Y><D><L><N><A><L><H><K><A><T><K><S><K><Q><H><L><G><G><S><Q><Q><L><L... | Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa.<BOP> | Q02383 |
Q8TDQ7 | GNPI2_HUMAN | Glucosamine-6-phosphate isomerase SB52 | Homo | <M><R><L><V><I><L><D><N><Y><D><L><A><S><E><W><A><A><K><Y><I><C><N><R><I><I><Q><F><K><P><G><Q><D><R><Y><F><T><L><G><L><P><T><G><S><T><P><L><G><C><Y><K><K><L><I><E><Y><H><K><N><G><H><L><S><F><K><Y><V><K><T><F><N><M><D><E><Y><V><G><L><P><R><N><H><P><E><S><Y><H><S><Y><M><W><N><N><F><F><K><H><I><D><I><D><P><N><N><A><H><I><L... | Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway. Deamination is coupled to aldo-keto isomer... | Q8TDQ7 |
Q5TFQ8 | SIRBL_HUMAN | Signal-regulatory protein beta-1 isoform 3 | Homo | <M><P><V><P><A><S><W><P><H><L><P><S><P><F><L><L><M><T><L><L><L><G><R><L><T><G><V><A><G><E><E><E><L><Q><V><I><Q><P><D><K><S><I><S><V><A><A><G><E><S><A><T><L><H><C><T><V><T><S><L><I><P><V><G><P><I><Q><W><F><R><G><A><G><P><G><R><E><L><I><Y><N><Q><K><E><G><H><F><P><R><V><T><T><V><S><D><L><T><K><R><N><N><M><D><F><S><I><R><I... | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.<BOP> | Q5TFQ8 |
P00414 | COX3_HUMAN | Cytochrome c oxidase polypeptide III | Homo | <M><T><H><Q><S><H><A><Y><H><M><V><K><P><S><P><W><P><L><T><G><A><L><S><A><L><L><M><T><S><G><L><A><M><W><F><H><F><H><S><M><T><L><L><M><L><G><L><L><T><N><T><L><T><M><Y><Q><W><W><R><D><V><T><R><E><S><T><Y><Q><G><H><H><T><P><P><V><Q><K><G><L><R><Y><G><M><I><L><F><I><T><S><E><V><F><F><F><A><G><F><F><W><A><F><Y><H><S><S><L><A... | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | P00414 |
O00567 | NOP56_HUMAN | Nucleolar protein 5A | Homo | <M><V><L><L><H><V><L><F><E><H><A><V><G><Y><A><L><L><A><L><K><E><V><E><E><I><S><L><L><Q><P><Q><V><E><E><S><V><L><N><L><G><K><F><H><S><I><V><R><L><V><A><F><C><P><F><A><S><S><Q><V><A><L><E><N><A><N><A><V><S><E><G><V><V><H><E><D><L><R><L><L><L><E><T><H><L><P><S><K><K><K><K><V><L><L><G><V><G><D><P><K><I><G><A><A><I><Q><E><E... | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.<BOP> | O00567 |
P38117 | ETFB_HUMAN | Electron transfer flavoprotein subunit beta | Homo | <M><A><E><L><R><V><L><V><A><V><K><R><V><I><D><Y><A><V><K><I><R><V><K><P><D><R><T><G><V><V><T><D><G><V><K><H><S><M><N><P><F><C><E><I><A><V><E><E><A><V><R><L><K><E><K><K><L><V><K><E><V><I><A><V><S><C><G><P><A><Q><C><Q><E><T><I><R><T><A><L><A><M><G><A><D><R><G><I><H><V><E><V><P><P><A><E><A><E><R><L><G><P><L><Q><V><A><R><V... | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase . It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for n... | P38117 |
Q13823 | NOG2_HUMAN | Autoantigen NGP-1 | Homo | <M><V><K><P><K><Y><K><G><R><S><T><I><N><P><S><K><A><S><T><N><P><D><R><V><Q><G><A><G><G><Q><N><M><R><D><R><A><T><I><R><R><L><N><M><Y><R><Q><K><E><R><R><N><S><R><G><K><I><I><K><P><L><Q><Y><Q><S><T><V><A><S><G><T><V><A><R><V><E><P><N><I><K><W><F><G><N><T><R><V><I><K><Q><S><S><L><Q><K><F><Q><E><E><M><D><T><V><M><K><D><P><Y... | GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation . May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels .<BOP> | Q13823 |
P0DPB6 | RPAC2_HUMAN | hRPA19 | Homo | <M><E><E><D><Q><E><L><E><R><K><I><S><G><L><K><T><S><M><A><E><G><E><R><K><T><A><L><E><M><V><Q><A><A><G><T><D><R><H><C><V><T><F><V><L><H><E><E><D><H><T><L><G><N><S><L><R><Y><M><I><M><K><N><P><E><V><E><F><C><G><Y><T><T><T><H><P><S><E><S><K><I><N><L><R><I><Q><T><R><G><T><L><P><A><V><E><P><F><Q><R><G><L><N><E><L><M><N><V><C... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.<BOP> | P0DPB6 |
Q9H320 | VCX1_HUMAN | Variably charged protein X-B1 | Homo | <M><S><P><K><P><R><A><S><G><P><P><A><K><A><T><E><A><G><K><R><K><S><S><S><Q><P><S><P><S><D><P><K><K><K><T><T><K><V><A><K><K><G><K><A><V><R><R><G><R><R><G><K><K><G><A><A><T><K><M><A><A><V><T><A><P><E><A><E><S><A><P><A><A><P><G><P><S><D><Q><P><S><Q><E><L><P><Q><H><E><L><P><P><E><E><P><V><S><E><G><T><Q><H><D><P><L><S><Q><E... | May mediate a process in spermatogenesis or may play a role in sex ratio distortion.<BOP> | Q9H320 |
Q5VZM2 | RRAGB_HUMAN | Ras-related GTP-binding protein B | Homo | <M><E><E><S><D><S><E><K><T><T><E><K><E><N><L><G><P><R><M><D><P><P><L><G><E><P><E><G><S><L><G><W><V><L><P><N><T><A><M><K><K><K><V><L><L><M><G><K><S><G><S><G><K><T><S><M><R><S><I><I><F><A><N><Y><I><A><R><D><T><R><R><L><G><A><T><I><L><D><R><I><H><S><L><Q><I><N><S><S><L><S><T><Y><S><L><V><D><S><V><G><N><T><K><T><F><D><V><E... | Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade . Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form . In its active form participa... | Q5VZM2 |
P18627 | LAG3_HUMAN | Secreted lymphocyte activation gene 3 protein | Homo | <M><W><E><A><Q><F><L><G><L><L><F><L><Q><P><L><W><V><A><P><V><K><P><L><Q><P><G><A><E><V><P><V><V><W><A><Q><E><G><A><P><A><Q><L><P><C><S><P><T><I><P><L><Q><D><L><S><L><L><R><R><A><G><V><T><W><Q><H><Q><P><D><S><G><P><P><A><A><A><P><G><H><P><L><A><P><G><P><H><P><A><A><P><S><S><W><G><P><R><P><R><R><Y><T><V><L><S><V><G><P><G... | May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.<BOP> | P18627 |
A0A0C4DH35 | HV335_HUMAN | Probable non-functional immunoglobulin heavy variable 3-35 | Homo | <M><E><F><G><L><S><W><V><F><L><A><A><I><L><K><G><V><Q><C><E><V><Q><L><V><E><S><G><G><G><L><V><Q><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><S><N><S><D><M><N><W><V><H><Q><A><P><G><K><G><L><E><W><V><S><G><V><S><W><N><G><S><R><T><H><Y><A><D><S><V><K><G><R><F><I><I><S><R><D><N><S><R><N><T><L><Y><L><Q><T><N><S><L><R><A... | Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin heavy chains . Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved ... | A0A0C4DH35 |
Q5JSS6 | MEIG1_HUMAN | Meiosis expressed gene 1 protein homolog | Homo | <M><A><S><S><D><V><K><P><K><S><V><S><H><A><K><K><W><S><E><E><I><E><N><L><Y><R><F><Q><Q><A><G><Y><R><D><E><T><E><Y><R><Q><V><K><Q><V><S><M><V><D><R><W><P><E><T><G><Y><V><K><K><L><Q><R><R><D><N><T><F><Y><Y><Y><N><K><Q><R><E><C><D><D><K><E><V><H><K><V><K><I><Y><A><Y> | Essential for spermiogenesis.<BOP> | Q5JSS6 |
Q6ZVK8 | NUD18_HUMAN | Nucleoside diphosphate-linked moiety X motif 18 | Homo | <M><A><S><E><G><L><A><G><A><L><A><S><V><L><A><G><Q><G><S><S><V><H><S><C><D><S><A><P><A><G><E><P><P><A><P><V><R><L><R><K><N><V><C><Y><V><V><L><A><V><F><L><S><E><Q><D><E><V><L><L><I><Q><E><A><K><R><E><C><R><G><S><W><Y><L><P><A><G><R><M><E><P><G><E><T><I><V><E><A><L><Q><R><E><V><K><E><E><A><G><L><H><C><E><P><E><T><L><L><S... | Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or mi... | Q6ZVK8 |
Q8IXM3 | RM41_HUMAN | Mitochondrial large ribosomal subunit protein mL41 | Homo | <M><G><V><L><A><A><A><A><R><C><L><V><R><G><A><D><R><M><S><K><W><T><S><K><R><G><P><R><S><F><R><G><R><K><G><R><G><A><K><G><I><G><F><L><T><S><G><W><R><F><V><Q><I><K><E><M><V><P><E><F><V><V><P><D><L><T><G><F><K><L><K><P><Y><V><S><Y><L><A><P><E><S><E><E><T><P><L><T><A><A><Q><L><F><S><E><A><V><A><P><A><I><E><K><D><F><K><D><G... | Component of the mitochondrial ribosome large subunit . Also involved in apoptosis and cell cycle . Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at... | Q8IXM3 |
Q96MB7 | HARB1_HUMAN | Harbinger transposase-derived nuclease | Homo | <M><A><I><P><I><T><V><L><D><C><D><L><L><L><Y><G><R><G><H><R><T><L><D><R><F><K><L><D><D><V><T><D><E><Y><L><M><S><M><Y><G><F><P><R><Q><F><I><Y><Y><L><V><E><L><L><G><A><N><L><S><R><P><T><Q><R><S><R><A><I><S><P><E><T><Q><V><L><A><A><L><G><F><Y><T><S><G><S><F><Q><T><R><M><G><D><A><I><G><I><S><Q><A><S><M><S><R><C><V><A><N><V... | Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.<BOP> | Q96MB7 |
Q14520 | HABP2_HUMAN | Hyaluronan-binding protein 2 27 kDa light chain alternate form | Homo | <M><F><A><R><M><S><D><L><H><V><L><L><L><M><A><L><V><G><K><T><A><C><G><F><S><L><M><S><L><L><E><S><L><D><P><D><W><T><P><D><Q><Y><D><Y><S><Y><E><D><Y><N><Q><E><E><N><T><S><S><T><L><T><H><A><E><N><P><D><W><Y><Y><T><E><D><Q><A><D><P><C><Q><P><N><P><C><E><H><G><G><D><C><L><V><H><G><S><T><F><T><C><S><C><L><A><P><F><S><G><N><K... | Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inact... | Q14520 |
Q9H8H0 | NOL11_HUMAN | Nucleolar protein 11 | Homo | <M><A><A><L><E><E><E><F><T><L><S><S><V><V><L><S><A><G><P><E><G><L><L><G><V><E><Q><S><D><K><T><D><Q><F><L><V><T><D><S><G><R><T><V><I><L><Y><K><V><S><D><Q><K><P><L><G><S><W><S><V><K><Q><G><Q><I><I><T><C><P><A><V><C><N><F><Q><T><G><E><Y><V><V><V><H><D><N><K><V><L><R><I><W><N><N><E><D><V><N><L><D><K><V><F><K><A><T><L><S><A... | Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b.<BOP> | Q9H8H0 |
Q86V86 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 | Homo | <M><L><L><S><K><F><G><S><L><A><H><L><C><G><P><G><G><V><D><H><L><P><V><K><I><L><Q><P><A><K><A><D><K><E><S><F><E><K><A><Y><Q><V><G><A><V><L><G><S><G><G><F><G><T><V><Y><A><G><S><R><I><A><D><G><L><P><V><A><V><K><H><V><V><K><E><R><V><T><E><W><G><S><L><G><G><A><T><V><P><L><E><V><V><L><L><R><K><V><G><A><A><G><G><A><R><G><V><I... | Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell ... | Q86V86 |
P01599 | KV117_HUMAN | Ig kappa chain V-I region WEA | Homo | <M><D><M><R><V><P><A><Q><L><L><G><L><L><L><L><W><F><P><G><A><R><C><D><I><Q><M><T><Q><S><P><S><S><L><S><A><S><V><G><D><R><V><T><I><T><C><R><A><S><Q><G><I><R><N><D><L><G><W><Y><Q><Q><K><P><G><K><A><P><K><R><L><I><Y><A><A><S><S><L><Q><S><G><V><P><S><R><F><S><G><S><G><S><G><T><E><F><T><L><T><I><S><S><L><Q><P><E><D><F><A><T... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01599 |
P40121 | CAPG_HUMAN | Actin regulatory protein CAP-G | Homo | <M><Y><T><A><I><P><Q><S><G><S><P><F><P><G><S><V><Q><D><P><G><L><H><V><W><R><V><E><K><L><K><P><V><P><V><A><Q><E><N><Q><G><V><F><F><S><G><D><S><Y><L><V><L><H><N><G><P><E><E><V><S><H><L><H><L><W><I><G><Q><Q><S><S><R><D><E><Q><G><A><C><A><V><L><A><V><H><L><N><T><L><L><G><E><R><P><V><Q><H><R><E><V><Q><G><N><E><S><D><L><F><M... | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.<BOP> | P40121 |
Q96AB6 | NTAN1_HUMAN | Protein NH2-terminal asparagine deamidase | Homo | <M><P><L><L><V><E><G><R><R><V><R><L><P><Q><S><A><G><D><L><V><R><A><H><P><P><L><E><E><R><A><R><L><L><R><G><Q><S><V><Q><Q><V><G><P><Q><G><L><L><Y><V><Q><Q><R><E><L><A><V><T><S><P><K><D><G><S><I><S><I><L><G><S><D><D><A><T><T><C><H><I><V><V><L><R><H><T><G><N><G><A><T><C><L><T><H><C><D><G><T><D><T><K><A><E><V><P><L><I><M><N... | N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal... | Q96AB6 |
Q9BYI3 | HYCCI_HUMAN | Protein FAM126A | Homo | <M><F><T><S><E><K><G><V><V><E><E><W><L><S><E><F><K><T><L><P><E><T><S><L><P><N><Y><A><T><N><L><K><D><K><S><S><L><V><S><S><L><Y><K><V><I><Q><E><P><Q><S><E><L><L><E><P><V><C><H><Q><L><F><E><F><Y><R><S><G><E><E><Q><L><L><Q><F><T><L><Q><F><L><P><E><L><I><W><C><Y><L><A><V><S><A><S><R><N><V><H><S><S><G><C><I><E><A><L><L><L><G... | Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane . The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis . FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generatio... | Q9BYI3 |
Q3SY17 | S2552_HUMAN | Solute carrier family 25 member 52 | Homo | <M><I><D><S><E><A><H><E><K><R><P><P><I><L><T><S><S><K><Q><D><I><S><P><H><I><T><N><V><G><E><M><K><H><Y><L><C><G><C><C><A><A><F><N><N><V><A><I><T><Y><P><I><Q><K><V><L><F><R><Q><Q><L><Y><G><I><K><T><R><D><A><V><L><Q><L><R><R><D><G><F><R><N><L><Y><R><G><I><L><P><P><L><M><Q><K><T><T><T><L><A><L><M><F><G><L><Y><E><D><L><S><C... | Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria . Compared to SLC25A51, SLC25A52-mediated transport is not essential for the import of NAD(+) in mitochondria .<BOP> | Q3SY17 |
Q2WGJ8 | TM249_HUMAN | Transmembrane protein 249 | Homo | <M><P><K><G><R><A><G><S><L><P><T><T><S><I><G><W><R><F><Q><L><W><F><L><G><L><T><C><P><E><R><H><L><A><R><R><L><K><N><N><S><F><Y><P><F><V><Q><Q><E><P><N><V><F><V><L><E><Y><Y><L><D><T><L><W><K><G><M><L><L><F><I><I><S><V><V><L><V><S><F><S><S><L><R><E><V><Q><K><Q><E><T><W><V><F><L><V><Y><G><V><G><V><G><L><W><L><V><I><S><S><L... | Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation.<BOP> | Q2WGJ8 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.