accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q96I34 | PP16A_HUMAN | Myosin phosphatase-targeting subunit 3 | Homo | <M><A><E><H><L><E><L><L><A><E><M><P><M><V><G><R><M><S><T><Q><E><R><L><K><H><A><Q><K><R><R><A><Q><Q><V><K><M><W><A><Q><A><E><K><E><A><Q><G><K><K><G><P><G><E><R><P><R><K><E><A><A><S><Q><G><L><L><K><Q><V><L><F><P><P><S><V><V><L><L><E><A><A><A><R><N><D><L><E><E><V><R><Q><F><L><G><S><G><V><S><P><D><L><A><N><E><D><G><L><T><A... | Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.<BOP> | Q96I34 |
P01178 | NEU1_HUMAN | Neurophysin 1 | Homo | <M><A><G><P><S><L><A><C><C><L><L><G><L><L><A><L><T><S><A><C><Y><I><Q><N><C><P><L><G><G><K><R><A><A><P><D><L><D><V><R><K><C><L><P><C><G><P><G><G><K><G><R><C><F><G><P><N><I><C><C><A><E><E><L><G><C><F><V><G><T><A><E><A><L><R><C><Q><E><E><N><Y><L><P><S><P><C><Q><S><G><Q><K><A><C><G><S><G><G><R><C><A><V><L><G><L><C><C><S><P... | Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) .<BOP> | P01178 |
Q9NNX1 | TUFT1_HUMAN | Tuftelin | Homo | <M><N><G><T><R><N><W><C><T><L><V><D><V><H><P><E><D><Q><A><A><G><S><V><D><I><L><R><L><T><L><Q><G><E><L><T><G><D><E><L><E><H><I><A><Q><K><A><G><R><K><T><Y><A><M><V><S><S><H><S><A><G><H><S><L><A><S><E><L><V><E><S><H><D><G><H><E><E><I><I><K><V><Y><L><K><G><R><S><G><D><K><M><I><H><E><K><N><I><N><Q><L><K><S><E><V><Q><Y><I><Q... | Involved in the mineralization and structural organization of enamel.<BOP> | Q9NNX1 |
Q3ZCQ8 | TIM50_HUMAN | Mitochondrial import inner membrane translocase subunit TIM50 | Homo | <M><A><A><S><A><A><V><F><S><R><L><R><S><G><L><R><L><G><S><R><G><L><C><T><R><L><A><T><P><P><R><R><A><P><D><Q><A><A><E><I><G><S><R><G><S><T><K><A><Q><G><P><Q><Q><Q><P><G><S><E><G><P><S><Y><A><K><K><V><A><L><W><L><A><G><L><L><G><A><G><G><T><V><S><V><V><Y><I><F><G><N><N><P><V><D><E><N><G><A><K><I><P><D><E><F><D><N><D><P><I... | May participate in the release of snRNPs and SMN from the Cajal body.<BOP> | Q3ZCQ8 |
Q70Z44 | 5HT3D_HUMAN | Serotonin receptor 3D | Homo | <M><Q><K><H><S><P><G><P><P><A><L><A><L><L><S><Q><S><L><L><T><T><G><N><G><D><T><L><I><I><N><C><P><G><F><G><Q><H><R><V><D><P><A><A><F><Q><A><V><F><D><R><K><A><I><G><P><V><T><N><Y><S><V><A><T><H><V><N><I><S><F><T><L><S><A><I><W><N><C><Y><S><R><I><H><T><F><N><C><H><H><A><R><P><W><H><N><Q><F><V><Q><W><N><P><D><E><C><G><G><I... | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively ... | Q70Z44 |
O00230 | CORT_HUMAN | Cortistatin-17 | Homo | <M><P><L><S><P><G><L><L><L><L><L><L><S><G><A><T><A><T><A><A><L><P><L><E><G><G><P><T><G><R><D><S><E><H><M><Q><E><A><A><G><I><R><K><S><S><L><L><T><F><L><A><W><W><F><E><W><T><S><Q><A><S><A><G><P><L><I><G><E><E><A><R><E><V><A><R><R><Q><E><G><A><P><P><Q><Q><S><A><R><R><D><R><M><P><C><R><N><F><F><W><K><T><F><S><S><C><K> | Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs.<BOP> | O00230 |
P35611 | ADDA_HUMAN | Erythrocyte adducin subunit alpha | Homo | <M><N><G><D><S><R><A><A><V><V><T><S><P><P><P><T><T><A><P><H><K><E><R><Y><F><D><R><V><D><E><N><N><P><E><Y><L><R><E><R><N><M><A><P><D><L><R><Q><D><F><N><M><M><E><Q><K><K><R><V><S><M><I><L><Q><S><P><A><F><C><E><E><L><E><S><M><I><Q><E><Q><F><K><K><G><K><N><P><T><G><L><L><A><L><Q><Q><I><A><D><F><M><T><T><N><V><P><N><V><Y><P... | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.<BOP> | P35611 |
Q9UH99 | SUN2_HUMAN | Sad1/unc-84 protein-like 2 | Homo | <M><S><R><R><S><Q><R><L><T><R><Y><S><Q><G><D><D><D><G><S><S><S><S><G><G><S><S><V><A><G><S><Q><S><T><L><F><K><D><S><P><L><R><T><L><K><R><K><S><S><N><M><K><R><L><S><P><A><P><Q><L><G><P><S><S><D><A><H><T><S><Y><Y><S><E><S><L><V><H><E><S><W><F><P><P><R><S><S><L><E><E><L><H><G><D><A><N><W><G><E><D><L><R><V><R><R><R><R><G><T... | As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and i... | Q9UH99 |
P35368 | ADA1B_HUMAN | Alpha-1B adrenoreceptor | Homo | <M><N><P><D><L><D><T><G><H><N><T><S><A><P><A><H><W><G><E><L><K><N><A><N><F><T><G><P><N><Q><T><S><S><N><S><T><L><P><Q><L><D><I><T><R><A><I><S><V><G><L><V><L><G><A><F><I><L><F><A><I><V><G><N><I><L><V><I><L><S><V><A><C><N><R><H><L><R><T><P><T><N><Y><F><I><V><N><L><A><M><A><D><L><L><L><S><F><T><V><L><P><F><S><A><A><L><E><V... | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.<BOP> | P35368 |
Q92503 | S14L1_HUMAN | SEC14-like protein 1 | Homo | <M><V><Q><K><Y><Q><S><P><V><R><V><Y><K><Y><P><F><E><L><I><M><A><A><Y><E><R><R><F><P><T><C><P><L><I><P><M><F><V><G><S><D><T><V><N><E><F><K><S><E><D><G><A><I><H><V><I><E><R><R><C><K><L><D><V><D><A><P><R><L><L><K><K><I><A><G><V><D><Y><V><Y><F><V><Q><K><N><S><L><N><S><R><E><R><T><L><H><I><E><A><Y><N><E><T><F><S><N><R><V><I... | May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation . May also regulate the SLC1... | Q92503 |
O94923 | GLCE_HUMAN | Heparosan-N-sulfate-glucuronate 5-epimerase | Homo | <M><R><C><L><A><A><R><V><N><Y><K><T><L><I><I><I><C><A><L><F><T><L><V><T><V><L><L><W><N><K><C><S><S><D><K><A><I><Q><F><P><R><R><S><S><S><G><F><R><V><D><G><F><E><K><R><A><A><A><S><E><S><N><N><Y><M><N><H><V><A><K><Q><Q><S><E><E><A><F><P><Q><E><Q><Q><K><A><P><P><V><V><G><G><F><N><S><N><V><G><S><K><V><L><G><L><K><Y><E><E><I... | Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.<BOP> | O94923 |
O75493 | CAH11_HUMAN | Carbonic anhydrase-related protein 2 | Homo | <M><G><A><A><A><R><L><S><A><P><R><A><L><V><L><W><A><A><L><G><A><A><A><H><I><G><P><A><P><D><P><E><D><W><W><S><Y><K><D><N><L><Q><G><N><F><V><P><G><P><P><F><W><G><L><V><N><A><A><W><S><L><C><A><V><G><K><R><Q><S><P><V><D><V><E><L><K><R><V><L><Y><D><P><F><L><P><P><L><R><L><S><T><G><G><E><K><L><R><G><T><L><Y><N><T><G><R><H><V... | Does not have a catalytic activity.<BOP> | O75493 |
Q7L2R6 | ZN765_HUMAN | Zinc finger protein 765 | Homo | <M><A><L><P><Q><G><L><L><T><F><R><D><V><A><I><E><F><S><Q><E><E><W><K><C><L><D><P><A><Q><R><T><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><S><L><D><I><S><S><K><C><M><M><K><E><F><S><S><T><A><Q><G><N><R><E><V><F><H><A><G><T><S><Q><R><H><E><S><H><H><N><G><D><F><C><F><Q><D><I><D><K><D><I><H><D><I><E><F><Q><W><Q><E><D><E><R><N... | May be involved in transcriptional regulation.<BOP> | Q7L2R6 |
Q96LA6 | FCRL1_HUMAN | Immune receptor translocation-associated protein 5 | Homo | <M><L><P><R><L><L><L><L><I><C><A><P><L><C><E><P><A><E><L><F><L><I><A><S><P><S><H><P><T><E><G><S><P><V><T><L><T><C><K><M><P><F><L><Q><S><S><D><A><Q><F><Q><F><C><F><F><R><D><T><R><A><L><G><P><G><W><S><S><S><P><K><L><Q><I><A><A><M><W><K><E><D><T><G><S><Y><W><C><E><A><Q><T><M><A><S><K><V><L><R><S><R><R><S><Q><I><N><V><H><R... | May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.<BOP> | Q96LA6 |
Q7L4E1 | MIGA2_HUMAN | Protein FAM73B | Homo | <M><A><F><R><R><A><E><G><T><S><M><I><Q><A><L><A><M><T><V><A><E><I><P><V><F><L><Y><T><T><F><G><Q><S><A><F><S><Q><L><R><L><T><P><G><L><R><K><V><L><F><A><T><A><L><G><T><V><A><L><A><L><A><A><H><Q><L><K><R><R><R><R><R><K><K><Q><V><G><P><E><M><G><G><E><Q><L><G><T><V><P><L><P><I><L><L><A><R><K><V><P><S><V><K><K><G><Y><S><S><R... | Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD.<BOP> | Q7L4E1 |
A0A0C4DH28 | TRGV4_HUMAN | T cell receptor gamma variable 4 | Homo | <M><Q><W><A><L><A><V><L><L><A><F><L><S><P><A><S><Q><K><S><S><N><L><E><G><R><T><K><S><V><I><R><Q><T><G><S><S><A><E><I><T><C><D><L><A><E><G><S><T><G><Y><I><H><W><Y><L><H><Q><E><G><K><A><P><Q><R><L><L><Y><Y><D><S><Y><T><S><S><V><V><L><E><S><G><I><S><P><G><K><Y><D><T><Y><G><S><T><R><K><N><L><R><M><I><L><R><N><L><I><E><N><D... | V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition . Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids present... | A0A0C4DH28 |
Q6ZUV0 | BACHL_HUMAN | Acyl-CoA thioesterase 7-like | Homo | <M><I><K><E><A><G><A><I><I><S><T><R><H><C><N><P><Q><N><G><D><R><C><V><A><A><L><A><R><V><E><C><T><H><F><L><W><P><M><C><I><G><E><V><A><H><V><S><A><E><I><T><Y><T><S><K><H><S><V><E><V><Q><V><N><M><M><S><E><N><I><L><T><G><A><K><K><L><T><N><K><A><T><L><W><Y><A><P><L><S><L><T><N><V><D><K><V><L><E><E><P><P><V><V><Y><F><R><Q><E... | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.<BOP> | Q6ZUV0 |
Q8IZI9 | IFNL3_HUMAN | Interleukin-28C | Homo | <M><T><G><D><C><M><P><V><L><V><L><M><A><A><V><L><T><V><T><G><A><V><P><V><A><R><L><R><G><A><L><P><D><A><R><G><C><H><I><A><Q><F><K><S><L><S><P><Q><E><L><Q><A><F><K><R><A><K><D><A><L><E><E><S><L><L><L><K><D><C><K><C><R><S><R><L><F><P><R><T><W><D><L><R><Q><L><Q><V><R><E><R><P><V><A><L><E><A><E><L><A><L><T><L><K><V><L><E><A... | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/S... | Q8IZI9 |
Q5EBM4 | ZN542_HUMAN | Zinc finger protein 542 pseudogene | Homo | <M><L><E><N><Y><Q><N><L><V><W><L><G><L><S><I><S><K><S><V><I><S><L><L><E><K><R><K><L><P><W><I><M><A><K><E><E><I><R><G><P><L><P><G><Y><F><K><V><S><E><M><T><I><S><Q><E><P><K><A><K><T><R><T><L><F><G><K><D><V><P><G><A><E><I><K><E><L><S><A><K><R><A><I><N><E><V><L><S><Q><F><D><T><V><I><K><C><T><R><N><V><C><K><E><C><G><N><L><Y... | May be involved in transcriptional regulation.<BOP> | Q5EBM4 |
P55273 | CDN2D_HUMAN | p19-INK4d | Homo | <M><L><L><E><E><V><R><A><G><D><R><L><S><G><A><A><A><R><G><D><V><Q><E><V><R><R><L><L><H><R><E><L><V><H><P><D><A><L><N><R><F><G><K><T><A><L><Q><V><M><M><F><G><S><T><A><I><A><L><E><L><L><K><Q><G><A><S><P><N><V><Q><D><T><S><G><T><S><P><V><H><D><A><A><R><T><G><F><L><D><T><L><K><V><L><V><E><H><G><A><D><V><N><V><P><D><G><T><G... | Interacts strongly with CDK4 and CDK6 and inhibits them.<BOP> | P55273 |
Q13427 | PPIG_HUMAN | Rotamase G | Homo | <M><G><I><K><V><Q><R><P><R><C><F><F><D><I><A><I><N><N><Q><P><A><G><R><V><V><F><E><L><F><S><D><V><C><P><K><T><C><E><N><F><R><C><L><C><T><G><E><K><G><T><G><K><S><T><Q><K><P><L><H><Y><K><S><C><L><F><H><R><V><V><K><D><F><M><V><Q><G><G><D><F><S><E><G><N><G><R><G><G><E><S><I><Y><G><G><F><F><E><D><E><S><F><A><V><K><H><N><K><E... | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding . May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.<BOP> | Q13427 |
Q15697 | ZN174_HUMAN | Zinc finger and SCAN domain-containing protein 8 | Homo | <M><A><A><K><M><E><I><T><L><S><S><N><T><E><A><S><S><K><Q><E><R><H><I><I><A><K><L><E><E><K><R><G><P><P><L><Q><K><N><C><P><D><P><E><L><C><R><Q><S><F><R><R><F><C><Y><Q><E><V><S><G><P><Q><E><A><L><S><Q><L><R><Q><L><C><R><Q><W><L><Q><P><E><L><H><T><K><E><Q><I><L><E><L><L><V><M><E><Q><F><L><T><I><L><P><P><E><I><Q><A><R><V><R... | Transcriptional repressor.<BOP> | Q15697 |
Q9Y5U4 | INSI2_HUMAN | Insulin-induced gene 2 protein | Homo | <M><A><E><G><E><T><E><S><P><G><P><K><K><C><G><P><Y><I><S><S><V><T><S><Q><S><V><N><L><M><I><R><G><V><V><L><F><F><I><G><V><F><L><A><L><V><L><N><L><L><Q><I><Q><R><N><V><T><L><F><P><P><D><V><I><A><S><I><F><S><S><A><W><W><V><P><P><C><C><G><T><A><S><A><V><I><G><L><L><Y><P><C><I><D><R><H><L><G><E><P><H><K><F><K><R><E><W><S><S... | Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR . Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, th... | Q9Y5U4 |
O75367 | H2AY_HUMAN | Medulloblastoma antigen MU-MB-50.205 | Homo | <M><S><S><R><G><G><K><K><K><S><T><K><T><S><R><S><A><K><A><G><V><I><F><P><V><G><R><M><L><R><Y><I><K><K><G><H><P><K><Y><R><I><G><V><G><A><P><V><Y><M><A><A><V><L><E><Y><L><T><A><E><I><L><E><L><A><G><N><A><A><R><D><N><K><K><G><R><V><T><P><R><H><I><L><L><A><V><A><N><D><E><E><L><N><Q><L><L><K><G><V><T><I><A><S><G><G><V><L><P... | In contrast to isoform 1, does not bind poly-ADP-ribose . Represses SOD3 gene expression .<BOP> | O75367 |
P20061 | TCO1_HUMAN | Transcobalamin I | Homo | <M><R><Q><S><H><Q><L><P><L><V><G><L><L><L><F><S><F><I><P><S><Q><L><C><E><I><C><E><V><S><E><E><N><Y><I><R><L><K><P><L><L><N><T><M><I><Q><S><N><Y><N><R><G><T><S><A><V><N><V><V><L><S><L><K><L><V><G><I><Q><I><Q><T><L><M><Q><K><M><I><Q><Q><I><K><Y><N><V><K><S><R><L><S><D><V><S><S><G><E><L><A><L><I><I><L><A><L><G><V><C><R><N... | Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.<BOP> | P20061 |
P01772 | HV333_HUMAN | Ig heavy chain V-III region KOL | Homo | <M><E><F><G><L><S><W><V><F><L><V><A><L><L><R><G><V><Q><C><Q><V><Q><L><V><E><S><G><G><G><V><V><Q><P><G><R><S><L><R><L><S><C><A><A><S><G><F><T><F><S><S><Y><G><M><H><W><V><R><Q><A><P><G><K><G><L><E><W><V><A><V><I><W><Y><D><G><S><N><K><Y><Y><A><D><S><V><K><G><R><F><T><I><S><R><D><N><S><K><N><T><L><Y><L><Q><M><N><S><L><R><A... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01772 |
Q16384 | SSX1_HUMAN | Synovial sarcoma, X breakpoint 1 | Homo | <M><N><G><D><D><T><F><A><K><R><P><R><D><D><A><K><A><S><E><K><R><S><K><A><F><D><D><I><A><T><Y><F><S><K><K><E><W><K><K><M><K><Y><S><E><K><I><S><Y><V><Y><M><K><R><N><Y><K><A><M><T><K><L><G><F><K><V><T><L><P><P><F><M><C><N><K><Q><A><T><D><F><Q><G><N><D><F><D><N><D><H><N><R><R><I><Q><V><E><H><P><Q><M><T><F><G><R><L><H><R><I... | Could act as a modulator of transcription.<BOP> | Q16384 |
P52747 | ZN143_HUMAN | Selenocysteine tRNA gene transcription-activating factor | Homo | <M><L><L><A><Q><I><N><R><D><S><Q><G><M><T><E><F><P><G><G><G><M><E><A><Q><H><V><T><L><C><L><T><E><A><V><T><V><A><D><G><D><N><L><E><N><M><E><G><V><S><L><Q><A><V><T><L><A><D><G><S><T><A><Y><I><Q><H><N><S><K><D><A><K><L><I><D><G><Q><V><I><Q><L><E><D><G><S><A><A><Y><V><Q><H><V><P><I><P><K><S><T><G><D><S><L><R><L><E><D><G><Q... | Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.<BOP> | P52747 |
A0A075B6N3 | TVBX1_HUMAN | T cell receptor beta variable 24-1 | Homo | <M><A><S><L><L><F><F><C><G><A><F><Y><L><L><G><T><G><S><M><D><A><D><V><T><Q><T><P><R><N><R><I><T><K><T><G><K><R><I><M><L><E><C><S><Q><T><K><G><H><D><R><M><Y><W><Y><R><Q><D><P><G><L><G><L><Q><L><I><Y><Y><S><F><D><V><K><D><I><N><K><G><E><I><S><D><G><Y><S><V><S><R><Q><A><Q><A><K><F><S><L><S><L><E><S><A><I><P><N><Q><T><A><L... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A075B6N3 |
Q8N9L1 | ZIC4_HUMAN | Zinc finger protein of the cerebellum 4 | Homo | <M><R><Y><K><T><S><L><V><M><R><K><R><L><R><L><Y><R><N><T><L><K><E><S><S><S><S><S><G><H><H><G><P><Q><L><T><A><A><S><S><P><S><V><F><P><G><L><H><E><E><P><P><Q><A><S><P><S><R><P><L><N><G><L><L><R><L><G><L><P><G><D><M><Y><A><R><P><E><P><F><P><P><G><P><A><A><R><S><D><A><L><A><A><A><A><A><L><H><G><Y><G><G><M><N><L><T><V><N><L... | Binds to DNA.<BOP> | Q8N9L1 |
O75563 | SKAP2_HUMAN | Src-associated adapter protein with PH and SH3 domains | Homo | <M><P><N><P><S><S><T><S><S><P><Y><P><L><P><E><E><I><R><N><L><L><A><D><V><E><T><F><V><A><D><I><L><K><G><E><N><L><S><K><K><A><K><E><K><R><E><S><L><I><K><K><I><K><D><V><K><S><I><Y><L><Q><E><F><Q><D><K><G><D><A><E><D><G><E><E><Y><D><D><P><F><A><G><P><P><D><T><I><S><L><A><S><E><R><Y><D><K><D><D><E><A><P><S><D><G><A><Q><F><P... | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.<BOP> | O75563 |
Q9H3V2 | MS4A5_HUMAN | Testis-expressed transmembrane protein 4 | Homo | <M><D><S><S><T><A><H><S><P><V><F><L><V><F><P><P><E><I><T><A><S><E><Y><E><S><T><E><L><S><A><T><T><F><S><T><Q><S><P><L><Q><K><L><F><A><R><K><M><K><I><L><G><T><I><Q><I><L><F><G><I><M><T><F><S><F><G><V><I><F><L><F><T><L><L><K><P><Y><P><R><F><P><F><I><F><L><S><G><Y><P><F><W><G><S><V><L><F><I><N><S><G><A><F><L><I><A><V><K><R... | May be involved in signal transduction as a component of a multimeric receptor complex.<BOP> | Q9H3V2 |
Q96PD5 | PGRP2_HUMAN | Peptidoglycan recognition protein long | Homo | <M><A><Q><G><V><L><W><I><L><L><G><L><L><L><W><S><D><P><G><T><A><S><L><P><L><L><M><D><S><V><I><Q><A><L><A><E><L><E><Q><K><V><P><A><A><K><T><R><H><T><A><S><A><W><L><M><S><A><P><N><S><G><P><H><N><R><L><Y><H><F><L><L><G><A><W><S><L><N><A><T><E><L><D><P><C><P><L><S><P><E><L><L><G><L><T><K><E><V><A><R><H><D><V><R><E><G><K><E... | May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.<BOP> | Q96PD5 |
Q8N141 | ZFP82_HUMAN | Zinc finger protein 545 | Homo | <M><A><L><R><S><V><M><F><S><D><V><S><I><D><F><S><P><E><E><W><E><Y><L><D><L><E><Q><K><D><L><Y><R><D><V><M><L><E><N><Y><S><N><L><V><S><L><G><C><F><I><S><K><P><D><V><I><S><S><L><E><Q><G><K><E><P><W><K><V><V><R><K><G><R><R><Q><Y><P><D><L><E><T><K><Y><E><T><K><K><L><S><L><E><N><D><I><Y><E><I><N><L><S><Q><W><K><I><M><E><R><I... | May be involved in transcriptional regulation.<BOP> | Q8N141 |
Q5JXM2 | MET24_HUMAN | Probable methyltransferase-like protein 24 | Homo | <M><A><R><E><R><P><P><G><R><G><C><G><V><L><R><R><C><L><L><G><A><V><L><L><F><G><L><R><L><C><A><E><L><R><R><A><G><P><G><S><P><T><R><S><A><P><P><G><P><A><W><R><P><P><G><P><H><L><P><P><A><P><G><Q><P><R><G><A><S><R><R><Q><V><T><Y><V><R><S><G><R><R><A><P><P><G><G><G><G><S><G><T><P><E><P><G><C><C><A><P><R><G><R><P><R><R><K><G... | Probable methyltransferase.<BOP> | Q5JXM2 |
P17032 | ZN37A_HUMAN | Zinc finger protein KOX21 | Homo | <M><I><T><S><Q><G><S><V><S><F><R><D><V><T><V><G><F><T><Q><E><E><W><Q><H><L><D><P><A><Q><R><T><L><Y><R><D><V><M><L><E><N><Y><S><H><L><V><S><V><G><Y><C><I><P><K><P><E><V><I><L><K><L><E><K><G><E><E><P><W><I><L><E><E><K><F><P><S><Q><S><H><L><E><L><I><N><T><S><R><N><Y><S><I><M><K><F><N><E><F><N><K><G><G><K><C><F><C><D><E><K... | May be involved in transcriptional regulation.<BOP> | P17032 |
B2RBV5 | MRUPP_HUMAN | Unnamed protein product | Homo | <M><R><P><V><D><A><D><E><A><R><E><P><R><E><E><P><G><S><P><L><S><P><A><P><R><A><G><R><E><N><L><A><S><L><E><R><E><R><A><R><A><H><W><R><A><R><R><K><L><L><E><I><Q><S><L><L><D><A><I><K><S><E><V><E><A><E><E><R><G><A><R><A><P><A><P><R><P><R><A><E><A><E><E><R><V><A><R><L><C><A><E><A><E><R><K><A><A><E><A><A><R><M><G><R><R><I><V... | May play a role in cell proliferation.<BOP> | B2RBV5 |
Q8NGE8 | OR4D9_HUMAN | Olfactory receptor OR11-253 | Homo | <M><D><Q><R><N><Y><T><R><V><K><E><F><T><F><L><G><I><T><Q><S><R><E><L><S><Q><V><L><F><T><F><L><F><L><V><Y><M><T><T><L><M><G><N><F><L><I><M><V><T><V><T><C><E><S><H><L><H><T><P><M><Y><F><L><L><R><N><L><S><I><L><D><I><C><F><S><S><I><T><A><P><K><V><L><I><D><L><L><S><E><T><K><T><I><S><F><S><G><C><V><T><Q><M><F><F><F><H><L><L... | Odorant receptor.<BOP> | Q8NGE8 |
Q9NQ31 | AKIP1_HUMAN | Proline-rich protein BCA3 | Homo | <M><D><N><C><L><A><A><A><A><L><N><G><V><D><R><R><S><L><Q><R><S><A><R><L><A><L><E><V><L><E><R><A><K><R><R><A><V><D><W><H><A><L><E><R><P><K><G><C><M><G><V><L><A><R><E><A><P><H><L><E><K><Q><P><A><A><G><P><Q><R><V><L><P><G><E><R><E><E><R><P><P><T><L><S><A><S><F><R><T><M><A><E><F><M><D><Y><T><S><S><Q><C><G><K><Y><Y><S><S><V... | Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.<BOP> | Q9NQ31 |
P0C5Z0 | H2AB2_HUMAN | H2A Barr body-deficient | Homo | <M><P><R><R><R><R><R><R><G><S><S><G><A><G><G><R><G><R><T><C><S><R><T><V><R><A><E><L><S><F><S><V><S><Q><V><E><R><S><L><R><E><G><H><Y><A><Q><R><L><S><R><T><A><P><V><Y><L><A><A><V><I><E><Y><L><T><A><K><V><L><E><L><A><G><N><E><A><Q><N><S><G><E><R><N><I><T><P><L><L><L><D><M><V><V><H><N><D><R><L><L><S><T><L><F><N><T><T><T><I... | Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in tr... | P0C5Z0 |
Q53ET0 | CRTC2_HUMAN | Transducer of regulated cAMP response element-binding protein 2 | Homo | <M><A><T><S><G><A><N><G><P><G><S><A><T><A><S><A><S><N><P><R><K><F><S><E><K><I><A><L><Q><K><Q><R><Q><A><E><E><T><A><A><F><E><E><V><M><M><D><I><G><S><T><R><L><Q><A><Q><K><L><R><L><A><Y><T><R><S><S><H><Y><G><G><S><L><P><N><V><N><Q><I><G><S><G><L><A><E><F><Q><S><P><L><H><S><P><L><D><S><S><R><S><T><R><H><H><G><L><V><E><R><V... | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CR... | Q53ET0 |
Q8TBA6 | GOGA5_HUMAN | RET-fused gene 5 protein | Homo | <M><S><W><F><V><D><L><A><G><K><A><E><D><L><L><N><R><V><D><Q><G><A><A><T><A><L><S><R><K><D><N><A><S><N><I><Y><S><K><N><T><D><Y><T><E><L><H><Q><Q><N><T><D><L><I><Y><Q><T><G><P><K><S><T><Y><I><S><S><A><A><D><N><I><R><N><Q><K><A><T><I><L><A><G><T><A><N><V><K><V><G><S><R><T><P><V><E><A><S><H><P><V><E><N><A><S><V><P><R><P><S... | Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.<BOP> | Q8TBA6 |
A2IDD5 | CCD78_HUMAN | hsCCDC78 | Homo | <M><E><H><A><A><T><T><G><P><R><P><G><P><P><S><R><R><V><E><N><V><V><L><R><A><K><D><W><L><P><G><A><P><G><G><T><A><V><W><A><T><S><L><E><A><E><V><P><P><D><L><A><L><N><K><E><Q><Q><L><Q><I><S><K><E><L><V><D><I><Q><I><T><T><H><H><L><H><E><Q><H><E><A><E><I><F><Q><L><K><S><E><I><L><R><L><E><S><R><V><L><E><L><E><L><R><G><D><G><T... | Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification... | A2IDD5 |
Q3LI66 | KRA62_HUMAN | Keratin-associated protein 6-2 | Homo | <M><C><G><S><Y><Y><G><N><Y><Y><G><D><H><G><Y><G><C><C><G><Y><E><G><L><G><Y><G><Y><G><S><L><R><C><G><Y><S><S><C><C><G><Y><G><H><G><Y><G><S><R><F><F><C><G><C><G><Y><G><C><G><S><G><Y><Y><Y> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q3LI66 |
Q6K0P9 | IFIX_HUMAN | Interferon-inducible protein X | Homo | <M><A><N><N><Y><K><K><I><V><L><L><K><G><L><E><V><I><N><D><Y><H><F><R><I><V><K><S><L><L><S><N><D><L><K><L><N><P><K><M><K><E><E><Y><D><K><I><Q><I><A><D><L><M><E><E><K><F><P><G><D><A><G><L><G><K><L><I><E><F><F><K><E><I><P><T><L><G><D><L><A><E><T><L><K><R><E><K><L><K><V><A><N><K><I><E><S><I><P><V><K><G><I><I><P><S><K><K><T... | Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer... | Q6K0P9 |
Q9NRB3 | CHSTC_HUMAN | Sulfotransferase Hlo | Homo | <M><T><K><A><R><L><F><R><L><W><L><V><L><G><S><V><F><M><I><L><L><I><I><V><Y><W><D><S><A><G><A><A><H><F><Y><L><H><T><S><F><S><R><P><H><T><G><P><P><L><P><T><P><G><P><D><R><D><R><E><L><T><A><D><S><D><V><D><E><F><L><D><K><F><L><S><A><G><V><K><Q><S><D><L><P><R><K><E><T><E><Q><P><P><A><P><G><S><M><E><E><S><V><R><G><Y><D><W><S... | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward par... | Q9NRB3 |
Q96AJ9 | VTI1A_HUMAN | Vti1-rp2 | Homo | <M><S><S><D><F><E><G><Y><E><Q><D><F><A><V><L><T><A><E><I><T><S><K><I><A><R><V><P><R><L><P><P><D><E><K><K><Q><M><V><A><N><V><E><K><Q><L><E><E><A><K><E><L><L><E><Q><M><D><L><E><V><R><E><I><P><P><Q><S><R><G><M><Y><S><N><R><M><R><S><Y><K><Q><E><M><G><K><L><E><T><D><F><K><R><S><R><I><A><Y><S><D><E><V><R><N><E><L><L><G><D><D... | V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi... | Q96AJ9 |
Q7RTN6 | STRAA_HUMAN | Serologically defined breast cancer antigen NY-BR-96 | Homo | <M><S><F><L><V><S><K><P><E><R><I><R><R><W><V><S><E><K><F><I><V><E><G><L><R><D><L><E><L><F><G><E><Q><P><P><G><D><T><R><R><K><T><N><D><A><S><S><E><S><I><A><S><F><S><K><Q><E><V><M><S><S><F><L><P><E><G><G><C><Y><E><L><L><T><V><I><G><K><G><F><E><D><L><M><T><V><N><L><A><R><Y><K><P><T><G><E><Y><V><T><V><R><R><I><N><L><E><A><C... | Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.<BOP> | Q7RTN6 |
Q6ZVT0 | TTL10_HUMAN | Tubulin--tyrosine ligase-like protein 10 | Homo | <M><D><H><S><C><T><R><F><I><H><R><R><G><P><P><T><R><T><R><A><G><F><K><R><G><K><R><P><R><I><Q><Q><R><P><R><A><R><V><S><G><T><I><P><A><S><R><L><H><P><A><P><A><S><Q><P><G><P><C><P><A><P><G><H><C><P><V><G><P><A><H><E><R><P><M><G><S><S><Q><E><E><G><L><R><C><Q><P><S><Q><P><D><H><D><A><D><G><H><C><G><P><D><L><E><G><A><E><R><A... | Inactive polyglycylase.<BOP> | Q6ZVT0 |
Q8NH85 | OR5R1_HUMAN | Olfactory receptor OR11-185 | Homo | <M><A><E><V><N><I><I><Y><V><T><V><F><I><L><K><G><I><T><N><R><P><E><L><Q><A><P><C><F><G><V><F><L><V><I><Y><L><V><T><V><L><G><N><L><G><L><I><T><L><I><K><I><D><T><R><L><H><T><P><M><Y><Y><F><L><S><H><L><A><F><V><D><L><C><Y><S><S><A><I><T><P><K><M><M><V><N><F><V><V><E><R><N><T><I><P><F><H><A><C><A><T><Q><L><G><C><F><L><T><F... | Odorant receptor.<BOP> | Q8NH85 |
Q14236 | EPAG_HUMAN | DIAPH2 antisense gene protein 1 | Homo | <M><N><L><Y><L><H><P><K><L><W><P><Q><L><A><G><T><K><T><L><H><V><A><D><A><Q><R><V><R><K><I><T><V><H><D><G><I><W><D><A><E><L><P><R><A><K><R><N><H><S><Y><H><L><R><Y><H><G><S><S><Y><S><R><C><F><L><E><R><Y><R><C><K><T><I><G><V><F><R><R><S><N><Q><P><D><C><L><E><T><R><S><E><K><A><K><N><R><D><G><V><V><Q><E><K><S><V><R><T><L><F... | May function as an early signal that helps mediate the activation of T-cells.<BOP> | Q14236 |
Q9Y3A5 | SBDS_HUMAN | Shwachman-Bodian-Diamond syndrome protein | Homo | <M><S><I><F><T><P><T><N><Q><I><R><L><T><N><V><A><V><V><R><M><K><R><A><G><K><R><F><E><I><A><C><Y><K><N><K><V><V><G><W><R><S><G><V><E><K><D><L><D><E><V><L><Q><T><H><S><V><F><V><N><V><S><K><G><Q><V><A><K><K><E><D><L><I><S><A><F><G><T><D><D><Q><T><E><I><C><K><Q><I><L><T><K><G><E><V><Q><V><S><D><K><E><R><H><T><Q><L><E><Q><M... | Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where i... | Q9Y3A5 |
P18846 | ATF1_HUMAN | Protein TREB36 | Homo | <M><E><D><S><H><K><S><T><T><S><E><T><A><P><Q><P><G><S><A><V><Q><G><A><H><I><S><H><I><A><Q><Q><V><S><S><L><S><E><S><E><E><S><Q><D><S><S><D><S><I><G><S><S><Q><K><A><H><G><I><L><A><R><R><P><S><Y><R><K><I><L><K><D><L><S><S><E><D><T><R><G><R><K><G><D><G><E><N><S><G><V><S><A><A><V><T><S><M><S><V><P><T><P><I><Y><Q><T><S><S><G... | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxificati... | P18846 |
Q9UI10 | EI2BD_HUMAN | eIF-2B GDP-GTP exchange factor subunit delta | Homo | <M><A><A><V><A><V><A><V><R><E><D><S><G><S><G><M><K><A><E><L><P><P><G><P><G><A><V><G><R><E><M><T><K><E><E><K><L><Q><L><R><K><E><K><K><Q><Q><K><K><K><R><K><E><E><K><G><A><E><P><E><T><G><S><A><V><S><A><A><Q><C><Q><V><G><P><T><R><E><L><P><E><S><G><I><Q><L><G><T><P><R><E><K><V><P><A><G><R><S><K><A><E><L><R><A><E><R><R><A><K... | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.<BOP> | Q9UI10 |
O76054 | S14L2_HUMAN | Supernatant protein factor | Homo | <M><S><G><R><V><G><D><L><S><P><R><Q><K><E><A><L><A><K><F><R><E><N><V><Q><D><V><L><P><A><L><P><N><P><D><D><Y><F><L><L><R><W><L><R><A><R><S><F><D><L><Q><K><S><E><A><M><L><R><K><H><V><E><F><R><K><Q><K><D><I><D><N><I><I><S><W><Q><P><P><E><V><I><Q><Q><Y><L><S><G><G><M><C><G><Y><D><L><D><G><C><P><V><W><Y><D><I><I><G><P><L><D... | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-t... | O76054 |
P26885 | FKBP2_HUMAN | Rotamase | Homo | <M><R><L><S><W><F><R><V><L><T><V><L><S><I><C><L><S><A><V><A><T><A><T><G><A><E><G><K><R><K><L><Q><I><G><V><K><K><R><V><D><H><C><P><I><K><S><R><K><G><D><V><L><H><M><H><Y><T><G><K><L><E><D><G><T><E><F><D><S><S><L><P><Q><N><Q><P><F><V><F><S><L><G><T><G><Q><V><I><K><G><W><D><Q><G><L><L><G><M><C><E><G><E><K><R><K><L><V><I><P... | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.<BOP> | P26885 |
Q13106 | ZN154_HUMAN | Zinc finger protein 154 | Homo | <M><A><A><A><T><L><R><T><P><T><Q><G><T><V><T><F><E><D><V><A><V><H><F><S><W><E><E><W><G><L><L><D><E><A><Q><R><C><L><Y><R><D><V><M><L><E><N><L><A><L><L><T><S><L><D><V><H><H><Q><K><Q><H><L><G><E><K><H><F><R><S><N><V><G><R><A><L><F><V><K><T><C><T><F><H><V><S><G><E><P><S><T><C><R><E><V><G><K><D><F><L><A><K><L><G><F><L><H><Q... | May be involved in transcriptional regulation.<BOP> | Q13106 |
Q99623 | PHB2_HUMAN | Repressor of estrogen receptor activity | Homo | <M><A><Q><N><L><K><D><L><A><G><R><L><P><A><G><P><R><G><M><G><T><A><L><K><L><L><L><G><A><G><A><V><A><Y><G><V><R><E><S><V><F><T><V><E><G><G><H><R><A><I><F><F><N><R><I><G><G><V><Q><Q><D><T><I><L><A><E><G><L><H><F><R><I><P><W><F><Q><Y><P><I><I><Y><D><I><R><A><R><P><R><K><I><S><S><P><T><G><S><K><D><L><Q><M><V><N><I><S><L><R... | (Microbial infection) Involved in human enterovirus 71/EV-71 infection by enhancing the autophagy mechanism during the infection.<BOP> | Q99623 |
Q9UI30 | TR112_HUMAN | tRNA methyltransferase 112 homolog | Homo | <M><K><L><L><T><H><N><L><L><S><S><H><V><R><G><V><G><S><R><G><F><P><L><R><L><Q><A><T><E><V><R><I><C><P><V><E><F><N><P><N><F><V><A><R><M><I><P><K><V><E><W><S><A><F><L><E><A><A><D><N><L><R><L><I><Q><V><P><K><G><P><V><E><G><Y><E><E><N><E><E><F><L><R><T><M><H><H><L><L><L><E><V><E><V><I><E><G><T><L><Q><C><P><E><S><G><R><M><F... | Acts as an activator of both rRNA/tRNA and protein methyltransferases . Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA . The heterodimer with N6AMT1/HEMK2 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor . The heterodimer with N6A... | Q9UI30 |
Q9P2X7 | DEC1_HUMAN | Candidate tumor suppressor CTS9 | Homo | <M><T><M><N><V><L><E><A><G><K><W><K><S><I><V><P><A><P><G><E><G><L><L><A><V><L><H><M><M><V><F><T><D><A><L><H><R><E><R><S><V><K><W><Q><A><G><V><C><Y><N><G><G><K><D><F><A><V><S><L><A><R><P><K><A><A><E><G><I><A><D> | Candidate tumor suppressor.<BOP> | Q9P2X7 |
Q5JPI3 | CC038_HUMAN | Uncharacterized protein C3orf38 | Homo | <M><E><M><S><G><L><S><F><S><E><M><E><G><C><R><N><L><L><G><L><L><D><N><D><E><I><M><A><L><C><D><T><V><T><N><R><L><V><Q><P><Q><D><R><Q><D><A><V><H><A><I><L><A><Y><S><Q><S><A><E><E><L><L><R><R><R><K><V><H><R><E><V><I><F><K><Y><L><A><T><Q><G><I><V><I><P><P><A><T><E><K><H><N><L><I><Q><H><A><K><D><Y><W><Q><K><Q><P><Q><L><K><L... | May be involved in apoptosis regulation.<BOP> | Q5JPI3 |
Q9NZP2 | OR6C2_HUMAN | HSA3 | Homo | <M><K><N><H><T><V><I><R><T><F><I><L><L><G><L><T><G><D><P><H><L><Q><V><L><L><F><I><F><L><F><L><T><Y><M><L><S><V><T><G><N><L><T><I><I><T><L><T><L><V><D><H><H><L><K><T><P><M><Y><F><F><L><R><N><F><S><F><L><E><V><S><F><T><T><V><C><I><P><R><F><L><Y><N><I><S><M><G><D><N><T><I><T><Y><N><A><C><A><S><Q><I><F><F><V><I><L><F><G><A... | Odorant receptor.<BOP> | Q9NZP2 |
Q96PM5 | ZN363_HUMAN | p53-induced RING-H2 protein | Homo | <M><A><A><T><A><R><E><D><G><A><S><G><Q><E><R><G><Q><R><G><C><E><H><Y><D><R><G><C><L><L><K><A><P><C><C><D><K><L><Y><T><C><R><L><C><H><D><N><N><E><D><H><Q><L><D><R><F><K><V><K><E><V><Q><C><I><N><C><E><K><I><Q><H><A><Q><Q><T><C><E><E><C><S><T><L><F><G><E><Y><Y><C><D><I><C><H><L><F><D><K><D><K><K><Q><Y><H><C><E><N><C><G><I... | Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription facto... | Q96PM5 |
Q9H9Y4 | GPN2_HUMAN | ATP-binding domain 1 family member B | Homo | <M><A><G><A><A><P><T><T><A><F><G><Q><A><V><I><G><P><P><G><S><G><K><T><T><Y><C><L><G><M><S><E><F><L><R><A><L><G><R><R><V><A><V><V><N><L><D><P><A><N><E><G><L><P><Y><E><C><A><V><D><V><G><E><L><V><G><L><G><D><V><M><D><A><L><R><L><G><P><N><G><G><L><L><Y><C><M><E><Y><L><E><A><N><L><D><W><L><R><A><K><L><D><P><L><R><G><H><Y><F... | Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.<BOP> | Q9H9Y4 |
P50440 | GATM_HUMAN | Transamidinase | Homo | <M><L><R><V><R><C><L><R><G><G><S><R><G><A><E><A><V><H><Y><I><G><S><R><L><G><R><T><L><T><G><W><V><Q><R><T><F><Q><S><T><Q><A><A><T><A><S><S><R><N><S><C><A><A><D><D><K><A><T><E><P><L><P><K><D><C><P><V><S><S><Y><N><E><W><D><P><L><E><E><V><I><V><G><R><A><E><N><A><C><V><P><P><F><T><I><E><V><K><A><N><T><Y><E><K><Y><W><P><F><Y... | Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.<BOP> | P50440 |
Q969E1 | LEAP2_HUMAN | Liver-expressed antimicrobial peptide 2 | Homo | <M><W><H><L><K><L><C><A><V><L><M><I><F><L><L><L><L><G><Q><I><D><G><S><P><I><P><E><V><S><S><A><K><R><R><P><R><R><M><T><P><F><W><R><G><V><S><L><R><P><I><G><A><S><C><R><D><D><S><E><C><I><T><R><L><C><R><K><R><R><C><S><L><S><V><A><Q><E> | Has an antimicrobial activity.<BOP> | Q969E1 |
P09681 | GIP_HUMAN | Incretin hormone | Homo | <M><V><A><T><K><T><F><A><L><L><L><L><S><L><F><L><A><V><G><L><G><E><K><K><E><G><H><F><S><A><L><P><S><L><P><V><G><S><H><A><K><V><S><S><P><Q><P><R><G><P><R><Y><A><E><G><T><F><I><S><D><Y><S><I><A><M><D><K><I><H><Q><Q><D><F><V><N><W><L><L><A><Q><K><G><K><K><N><D><W><K><H><N><I><T><Q><R><E><A><R><A><L><E><L><A><S><Q><A><N><R... | Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.<BOP> | P09681 |
Q96A23 | CPNE4_HUMAN | Copine-8 | Homo | <M><K><K><M><S><N><I><Y><E><S><A><A><N><T><L><G><I><F><N><S><P><C><L><T><K><V><E><L><R><V><A><C><K><G><I><S><D><R><D><A><L><S><K><P><D><P><C><V><I><L><K><M><Q><S><H><G><Q><W><F><E><V><D><R><T><E><V><I><R><T><C><I><N><P><V><Y><S><K><L><F><T><V><D><F><Y><F><E><E><V><Q><R><L><R><F><E><V><H><D><I><S><S><N><H><N><G><L><K><E... | Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.<BOP> | Q96A23 |
Q8IZR5 | CKLF4_HUMAN | Chemokine-like factor superfamily member 4 | Homo | <M><R><S><G><E><E><L><D><G><F><E><G><E><A><S><S><T><S><M><I><S><G><A><S><S><P><Y><Q><P><T><T><E><P><V><S><Q><R><R><G><L><A><G><L><R><C><D><P><D><Y><L><R><G><A><L><G><R><L><K><V><A><Q><V><I><L><A><L><I><A><F><I><C><I><E><T><I><M><A><C><S><P><C><E><G><L><Y><F><F><E><F><V><S><C><S><A><F><V><V><T><G><V><L><L><I><M><F><S><L... | Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.<BOP> | Q8IZR5 |
P23142 | FBLN1_HUMAN | Fibulin-1 | Homo | <M><E><R><A><A><P><S><R><R><V><P><L><P><L><L><L><L><G><G><L><A><L><L><A><A><G><V><D><A><D><V><L><L><E><A><C><C><A><D><G><H><R><M><A><T><H><Q><K><D><C><S><L><P><Y><A><T><E><S><K><E><C><R><M><V><Q><E><Q><C><C><H><S><Q><L><E><E><L><H><C><A><T><G><I><S><L><A><N><E><Q><D><R><C><A><T><P><H><G><D><N><A><S><L><E><A><T><F><V><K... | Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basem... | P23142 |
Q9Y253 | POLH_HUMAN | Xeroderma pigmentosum variant type protein | Homo | <M><A><T><G><Q><D><R><V><V><A><L><V><D><M><D><C><F><F><V><Q><V><E><Q><R><Q><N><P><H><L><R><N><K><P><C><A><V><V><Q><Y><K><S><W><K><G><G><G><I><I><A><V><S><Y><E><A><R><A><F><G><V><T><R><S><M><W><A><D><D><A><K><K><L><C><P><D><L><L><L><A><Q><V><R><E><S><R><G><K><A><N><L><T><K><Y><R><E><A><S><V><E><V><M><E><I><M><S><R><F><A... | DNA polymerase specifically involved in the DNA repair by translesion synthesis (TLS) . Due to low processivity on both damaged and normal DNA, cooperates with the heterotetrameric (REV3L, REV7, POLD2 and POLD3) POLZ complex for complete bypass of DNA lesions. Inserts one or 2 nucleotide(s) opposite the lesion, the pri... | Q9Y253 |
P32314 | FOXN2_HUMAN | Human T-cell leukemia virus enhancer factor | Homo | <M><G><P><V><I><G><M><T><P><D><K><R><A><E><T><P><G><A><E><K><I><A><G><L><S><Q><I><Y><K><M><G><S><L><P><E><A><V><D><A><A><R><P><K><A><T><L><V><D><S><E><S><A><D><D><E><L><T><N><L><N><W><L><H><E><S><T><N><L><L><T><N><F><S><L><G><S><E><G><L><P><I><V><S><P><L><Y><D><I><E><G><D><D><V><P><S><F><G><P><A><C><Y><Q><N><P><E><K><K... | Binds to the purine-rich region in HTLV-I LTR.<BOP> | P32314 |
Q96MP8 | KCTD7_HUMAN | BTB/POZ domain-containing protein KCTD7 | Homo | <M><V><V><V><T><G><R><E><P><D><S><R><R><Q><D><G><A><M><S><S><S><D><A><E><D><D><F><L><E><P><A><T><P><T><A><T><Q><A><G><H><A><L><P><L><L><P><Q><E><F><P><E><V><V><P><L><N><I><G><G><A><H><F><T><T><R><L><S><T><L><R><C><Y><E><D><T><M><L><A><A><M><F><S><G><R><H><Y><I><P><T><D><S><E><G><R><Y><F><I><D><R><D><G><T><H><F><G><D><V... | May be involved in the control of excitability of cortical neurons.<BOP> | Q96MP8 |
Q8IXF9 | AQ12A_HUMAN | Aquaporin-12A | Homo | <M><A><G><L><N><V><S><L><S><F><F><F><A><T><F><A><L><C><E><A><A><R><R><A><S><K><A><L><L><P><V><G><A><Y><E><V><F><A><R><E><A><M><R><T><L><V><E><L><G><P><W><A><G><D><F><G><P><D><L><L><L><T><L><L><F><L><L><F><L><A><H><G><V><T><L><D><G><A><S><A><N><P><T><V><S><L><Q><E><F><L><M><A><E><Q><S><L><P><G><T><L><L><K><L><A><A><Q><G... | Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.<BOP> | Q8IXF9 |
Q86SK9 | SCD5_HUMAN | Stearoyl-CoA desaturase 2 | Homo | <M><P><G><P><A><T><D><A><G><K><I><P><F><C><D><A><K><E><E><I><R><A><G><L><E><S><S><E><G><G><G><G><P><E><R><P><G><A><R><G><Q><R><Q><N><I><V><W><R><N><V><V><L><M><S><L><L><H><L><G><A><V><Y><S><L><V><L><I><P><K><A><K><P><L><T><L><L><W><A><Y><F><C><F><L><L><A><A><L><G><V><T><A><G><A><H><R><L><W><S><H><R><S><Y><R><A><K><L><P... | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA . Gives rise to a ... | Q86SK9 |
Q3SY84 | K2C71_HUMAN | Type-II keratin Kb34 | Homo | <M><S><R><Q><F><T><C><K><S><G><A><A><A><K><G><G><F><S><G><C><S><A><V><L><S><G><G><S><S><S><S><F><R><A><G><S><K><G><L><S><G><G><F><G><S><R><S><L><Y><S><L><G><G><V><R><S><L><N><V><A><S><G><S><G><K><S><G><G><Y><G><F><G><R><G><R><A><S><G><F><A><G><S><M><F><G><S><V><A><L><G><P><V><C><P><T><V><C><P><P><G><G><I><H><Q><V><T><V... | Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.<BOP> | Q3SY84 |
Q0P5N6 | ARL16_HUMAN | ADP-ribosylation factor-like protein 16 | Homo | <M><R><V><A><G><G><R><A><L><S><R><G><A><E><L><R><V><P><G><G><A><K><H><G><M><C><L><L><L><G><A><T><G><V><G><K><T><L><L><V><K><R><L><Q><E><V><S><S><R><D><G><K><G><D><L><G><E><P><P><P><T><R><P><T><V><G><T><N><L><T><D><I><V><A><Q><R><K><I><T><I><R><E><L><G><G><C><M><G><P><I><W><S><S><Y><Y><G><N><C><R><S><L><L><F><V><M><D><A... | May suppress the RNA sensing activity of DDX58 in a GTP-dependent.<BOP> | Q0P5N6 |
Q9UBI9 | HDC_HUMAN | Headcase protein homolog | Homo | <M><P><N><P><K><N><S><K><G><G><R><K><N><K><R><A><N><S><S><G><D><E><Q><E><N><G><A><G><A><L><A><A><A><G><A><A><G><A><A><A><G><G><A><L><A><A><A><A><G><C><G><A><A><A><A><G><A><P><G><A><G><G><A><A><G><A><G><G><A><G><T><G><A><A><N><A><A><A><A><A><G><A><A><A><A><G><D><A><K><N><E><A><P><C><A><T><P><L><I><C><S><F><G><R><P><V><D... | May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs.<BOP> | Q9UBI9 |
P29084 | T2EB_HUMAN | General transcription factor IIE subunit 2 | Homo | <M><D><P><S><L><L><R><E><R><E><L><F><K><K><R><A><L><S><T><P><V><V><E><K><R><S><A><S><S><E><S><S><S><S><S><S><K><K><K><K><T><K><V><E><H><G><G><S><S><G><S><K><Q><N><S><D><H><S><N><G><S><F><N><L><K><A><L><S><G><S><S><G><Y><K><F><G><V><L><A><K><I><V><N><Y><M><K><T><R><H><Q><R><G><D><T><H><P><L><T><L><D><E><I><L><D><E><T><Q... | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.<BOP> | P29084 |
Q7Z402 | TMC7_HUMAN | Transmembrane channel-like protein 7 | Homo | <M><S><E><S><S><G><S><A><L><Q><P><G><R><P><S><R><Q><P><A><V><H><P><E><N><L><S><L><D><S><S><C><F><S><S><P><P><V><N><F><L><Q><E><L><P><S><Y><R><S><I><A><R><R><R><T><T><V><H><S><R><D><K><Q><S><G><T><L><L><K><P><T><D><S><Y><S><S><Q><L><E><D><R><I><A><E><N><L><S><S><H><S><L><R><N><Y><A><L><N><I><S><E><K><R><R><L><R><D><I><Q... | Probable ion channel.<BOP> | Q7Z402 |
Q96ID5 | IGS21_HUMAN | Immunoglobulin superfamily member 21 | Homo | <M><R><T><A><P><S><L><R><R><C><V><C><L><L><L><A><A><I><L><D><L><A><R><G><Y><L><T><V><N><I><E><P><L><P><P><V><V><A><G><D><A><V><T><L><K><C><N><F><K><T><D><G><R><M><R><E><I><V><W><Y><R><V><T><D><G><G><T><I><K><Q><K><I><F><T><F><D><A><M><F><S><T><N><Y><S><H><M><E><N><Y><R><K><R><E><D><L><V><Y><Q><S><T><V><R><L><P><E><V><R... | Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.<BOP> | Q96ID5 |
Q53FV1 | ORML2_HUMAN | Adoplin-2 | Homo | <M><N><V><G><V><A><H><S><E><V><N><P><N><T><R><V><M><N><S><R><G><I><W><L><A><Y><I><I><L><V><G><L><L><H><M><V><L><L><S><I><P><F><F><S><I><P><V><V><W><T><L><T><N><V><I><H><N><L><A><T><Y><V><F><L><H><T><V><K><G><T><P><F><E><T><P><D><Q><G><K><A><R><L><L><T><H><W><E><Q><M><D><Y><G><L><Q><F><T><S><S><R><K><F><L><S><I><S><P><I... | Negative regulator of sphingolipid synthesis.<BOP> | Q53FV1 |
Q9H089 | LSG1_HUMAN | Large subunit GTPase 1 homolog | Homo | <M><G><R><R><R><A><P><A><G><G><S><L><G><R><A><L><M><R><H><Q><T><Q><R><S><R><S><H><R><H><T><D><S><W><L><H><T><S><E><L><N><D><G><Y><D><W><G><R><L><N><L><Q><S><V><T><E><Q><S><S><L><D><D><F><L><A><T><A><E><L><A><G><T><E><F><V><A><E><K><L><N><I><K><F><V><P><A><E><A><R><T><G><L><L><S><F><E><E><S><Q><R><I><K><K><L><H><E><E><N... | GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).<BOP> | Q9H089 |
Q9Y6N5 | SQOR_HUMAN | Sulfide quinone oxidoreductase | Homo | <M><V><P><L><V><A><V><V><S><G><P><R><A><Q><L><F><A><C><L><L><R><L><G><T><Q><Q><V><G><P><L><Q><L><H><T><G><A><S><H><A><A><R><N><H><Y><E><V><L><V><L><G><G><G><S><G><G><I><T><M><A><A><R><M><K><R><K><V><G><A><E><N><V><A><I><V><E><P><S><E><R><H><F><Y><Q><P><I><W><T><L><V><G><A><G><A><K><Q><L><S><S><S><G><R><P><T><A><S><V><I... | Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro) . It is believed the in vivo electron acceptor is glutath... | Q9Y6N5 |
Q9UNP4 | SIAT9_HUMAN | Sialyltransferase 9 | Homo | <M><R><T><K><A><A><G><C><A><E><R><R><P><L><Q><P><R><T><E><A><A><A><A><P><A><G><R><A><M><P><S><E><Y><T><Y><V><K><L><R><S><D><C><S><R><P><S><L><Q><W><Y><T><R><A><Q><S><K><M><R><R><P><S><L><L><L><K><D><I><L><K><C><T><L><L><V><F><G><V><W><I><L><Y><I><L><K><L><N><Y><T><T><E><E><C><D><M><K><K><M><H><Y><V><D><P><D><H><V><K><R... | Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesi... | Q9UNP4 |
O43908 | NKG2F_HUMAN | NKG2-F-activating NK receptor | Homo | <M><N><K><Q><R><G><T><Y><S><E><V><S><L><A><Q><D><P><K><R><Q><Q><R><K><L><K><G><N><K><I><S><I><S><G><T><K><Q><E><I><F><Q><V><E><L><N><L><Q><N><A><S><S><D><H><Q><G><N><D><K><T><Y><H><C><K><G><L><L><P><P><P><E><K><L><T><A><E><V><L><G><I><I><C><I><V><L><M><A><T><V><L><K><T><I><V><L><I><P><C><I><G><V><L><E><Q><N><N><F><S><L... | May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.<BOP> | O43908 |
Q9UBN6 | TR10D_HUMAN | TRAIL receptor with a truncated death domain | Homo | <M><G><L><W><G><Q><S><V><P><T><A><S><S><A><R><A><G><R><Y><P><G><A><R><T><A><S><G><T><R><P><W><L><L><D><P><K><I><L><K><F><V><V><F><I><V><A><V><L><L><P><V><R><V><D><S><A><T><I><P><R><Q><D><E><V><P><Q><Q><T><V><A><P><Q><Q><Q><R><R><S><L><K><E><E><E><C><P><A><G><S><H><R><S><E><Y><T><G><A><C><N><P><C><T><E><G><V><D><Y><T><I... | Receptor for the cytotoxic ligand TRAIL . Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis . Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMe... | Q9UBN6 |
P61550 | ENVT1_HUMAN | Transmembrane protein | Homo | <M><G><P><E><A><W><V><R><P><L><K><T><A><P><K><P><G><E><A><I><R><L><I><L><F><I><Y><L><S><C><F><F><L><P><V><M><S><S><E><P><S><Y><S><F><L><L><T><S><F><T><T><G><R><V><F><A><N><T><T><W><R><A><G><T><S><K><E><V><S><F><A><V><D><L><C><V><L><F><P><E><P><A><R><T><H><E><E><Q><H><N><L><P><V><I><G><A><G><S><V><D><L><A><A><G><F><G><H... | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.<BOP> | P61550 |
Q7LDI9 | GAK6_HUMAN | HERV-K_7p22.1 provirus ancestral Gag polyprotein | Homo | <M><G><Q><T><K><S><K><I><K><S><K><Y><A><S><Y><L><S><F><I><K><I><L><L><K><R><G><G><V><K><V><S><T><K><N><L><I><K><L><F><Q><I><I><E><Q><F><C><P><W><F><P><E><Q><G><T><L><D><L><K><D><W><K><R><I><G><K><E><L><K><Q><A><G><R><K><G><N><I><I><P><L><T><V><W><N><D><W><A><I><I><K><A><A><L><E><P><F><Q><T><E><E><D><S><V><S><V><S><D><A... | The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding ... | Q7LDI9 |
Q567U6 | CCD93_HUMAN | Coiled-coil domain-containing protein 93 | Homo | <M><G><L><P><R><G><P><E><G><Q><G><L><P><E><V><E><T><R><E><D><E><E><Q><N><V><K><L><T><E><I><L><E><L><L><V><A><A><G><Y><F><R><A><R><I><K><G><L><S><P><F><D><K><V><V><G><G><M><T><W><C><I><T><T><C><N><F><D><V><D><V><D><L><L><F><Q><E><N><S><T><I><G><Q><K><I><A><L><S><E><K><I><V><S><V><L><P><R><M><K><C><P><H><Q><L><E><P><H><Q... | (Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.<BOP> | Q567U6 |
Q8WVB3 | HEXD_HUMAN | N-acetyl-beta-galactosaminidase | Homo | <M><S><G><S><T><P><F><Q><M><R><L><V><H><L><D><L><K><G><A><P><P><K><V><S><Y><L><S><E><I><F><P><L><F><R><A><L><G><A><N><G><L><L><I><E><Y><E><D><M><F><P><Y><E><G><P><L><R><L><L><R><A><K><Y><A><Y><S><P><S><E><I><K><E><I><L><H><L><A><G><L><N><E><L><E><V><I><P><L><V><Q><T><F><G><H><M><E><F><V><L><K><H><T><A><F><A><H><L><R><E... | Has hexosaminidase activity. Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates. Has a preference for galactosaminide over glucosaminide substrates .<BOP> | Q8WVB3 |
Q15418 | KS6A1_HUMAN | Ribosomal S6 kinase 1 | Homo | <M><P><L><A><Q><L><K><E><P><W><P><L><M><E><L><V><P><L><D><P><E><N><G><Q><T><S><G><E><E><A><G><L><Q><P><S><K><D><E><G><V><L><K><E><I><S><I><T><H><H><V><K><A><G><S><E><K><A><D><P><S><H><F><E><L><L><K><V><L><G><Q><G><S><F><G><K><V><F><L><V><R><K><V><T><R><P><D><S><G><H><L><Y><A><M><K><V><L><K><K><A><T><L><K><V><R><D><R><V... | (Microbial infection) Promotes the late transcription and translation of viral lytic genes during Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, when constitutively activated.<BOP> | Q15418 |
Q9GZP4 | PITH1_HUMAN | PITH domain-containing protein 1 | Homo | <M><S><H><G><H><S><H><G><G><G><G><C><R><C><A><A><E><R><E><E><P><P><E><Q><R><G><L><A><Y><G><L><Y><L><R><I><D><L><E><R><L><Q><C><L><N><E><S><R><E><G><S><G><R><G><V><F><K><P><W><E><E><R><T><D><R><S><K><F><V><E><S><D><A><D><E><E><L><L><F><N><I><P><F><T><G><N><V><K><L><K><G><I><I><I><M><G><E><D><D><D><S><H><P><S><E><M><R><L... | Promotes megakaryocyte differentiation by up-regulating RUNX1 expression . Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene .<BOP> | Q9GZP4 |
Q14449 | GRB14_HUMAN | GRB14 adapter protein | Homo | <M><T><T><S><L><Q><D><G><Q><S><A><A><S><R><A><A><A><R><D><S><P><L><A><A><Q><V><C><G><A><A><Q><G><R><G><D><A><H><D><L><A><P><A><P><W><L><H><A><R><A><L><L><P><L><P><D><G><T><R><G><C><A><A><D><R><R><K><K><K><D><L><D><V><P><E><M><P><S><I><P><N><P><F><P><E><L><C><C><S><P><F><T><S><V><L><S><A><D><L><F><P><K><A><N><S><R><K><K... | Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in respons... | Q14449 |
P49903 | SPS1_HUMAN | Selenophosphate synthase 1 | Homo | <M><S><T><R><E><S><F><N><P><E><S><Y><E><L><D><K><S><F><R><L><T><R><F><T><E><L><K><G><T><G><C><K><V><P><Q><D><V><L><Q><K><L><L><E><S><L><Q><E><N><H><F><Q><E><D><E><Q><F><L><G><A><V><M><P><R><L><G><I><G><M><D><T><C><V><I><P><L><R><H><G><G><L><S><L><V><Q><T><T><D><Y><I><Y><P><I><V><D><D><P><Y><M><M><G><R><I><A><C><A><N><V... | Synthesizes selenophosphate from selenide and ATP.<BOP> | P49903 |
A6NNA5 | DRGX_HUMAN | Paired-related homeobox protein-like 1 | Homo | <M><F><Y><F><H><C><P><P><Q><L><E><G><T><A><T><F><G><N><H><S><S><G><D><F><D><D><G><F><L><R><R><K><Q><R><R><N><R><T><T><F><T><L><Q><Q><L><E><A><L><E><A><V><F><A><Q><T><H><Y><P><D><V><F><T><R><E><E><L><A><M><K><I><N><L><T><E><A><R><V><Q><V><W><F><Q><N><R><R><A><K><W><R><K><T><E><R><G><A><S><D><Q><E><P><G><A><K><E><P><M><A... | Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain.<BOP> | A6NNA5 |
Q9H221 | ABCG8_HUMAN | Sterolin-2 | Homo | <M><A><G><K><A><A><E><E><R><G><L><P><K><G><A><T><P><Q><D><T><S><G><L><Q><D><R><L><F><S><S><E><S><D><N><S><L><Y><F><T><Y><S><G><Q><P><N><T><L><E><V><R><D><L><N><Y><Q><V><D><L><A><S><Q><V><P><W><F><E><Q><L><A><Q><F><K><M><P><W><T><S><P><S><C><Q><N><S><C><E><L><G><I><Q><N><L><S><F><K><V><R><S><G><Q><M><L><A><I><I><G><S><S... | ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile . Required for normal s... | Q9H221 |
Q86UC2 | RSPH3_HUMAN | Radial spoke head-like protein 2 | Homo | <M><T><V><K><P><A><K><A><A><S><L><A><R><N><L><A><K><R><R><R><T><Y><L><G><G><A><A><G><R><S><Q><E><P><E><V><P><C><A><A><V><L><P><G><K><P><G><D><R><N><C><P><E><F><P><P><P><D><R><T><L><G><C><W><A><T><D><A><A><P><A><A><G><L><C><G><A><G><S><E><P><S><I><A><P><T><S><C><A><G><N><L><P><S><R><P><P><P><L><L><S><P><L><L><A><S><R><N... | Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia.<BOP> | Q86UC2 |
Q9UPY5 | XCT_HUMAN | xCT | Homo | <M><V><R><K><P><V><V><S><T><I><S><K><G><G><Y><L><Q><G><N><V><N><G><R><L><P><S><L><G><N><K><E><P><P><G><Q><E><K><V><Q><L><K><R><K><V><T><L><L><R><G><V><S><I><I><I><G><T><I><I><G><A><G><I><F><I><S><P><K><G><V><L><Q><N><T><G><S><V><G><M><S><L><T><I><W><T><V><C><G><V><L><S><L><F><G><A><L><S><Y><A><E><L><G><T><T><I><K><K><S... | Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.<BOP> | Q9UPY5 |
Q9Y5K1 | SPO11_HUMAN | Cancer/testis antigen 35 | Homo | <M><A><F><A><P><M><G><P><E><A><S><F><F><D><V><L><D><R><H><R><E><S><L><L><A><A><L><R><R><G><G><R><E><P><P><T><G><G><S><R><L><A><S><S><S><E><V><L><A><S><I><E><N><I><I><Q><D><I><I><T><S><L><A><R><N><E><A><P><A><F><T><I><D><N><R><S><S><W><E><N><I><K><F><E><D><S><V><G><L><Q><M><V><S><H><C><T><T><R><K><I><K><S><D><S><P><K><S... | Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavag... | Q9Y5K1 |
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