accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q9H0R1 | AP5M1_HUMAN | Putative HIV-1 infection-related protein | Homo | <M><A><Q><R><A><V><W><L><I><S><H><E><P><G><T><P><L><C><G><T><V><R><F><S><R><R><Y><P><T><V><E><K><R><A><R><V><F><N><G><A><S><Y><V><P><V><P><E><D><G><P><F><L><K><A><L><L><F><E><L><R><L><L><D><D><D><K><D><F><V><E><S><R><D><S><C><S><R><I><N><K><T><S><I><Y><G><L><L><I><G><G><E><E><L><W><P><V><V><A><F><L><K><N><D><M><I><Y><A... | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:18395520, it may play a role in cell death.<BOP> | Q9H0R1 |
Q9BZ23 | PANK2_HUMAN | Pantothenate kinase 2, mitochondrial mature form | Homo | <M><R><R><L><G><P><F><H><P><R><V><H><W><A><A><P><P><S><L><S><S><G><L><H><R><L><L><F><L><R><G><T><R><I><P><S><S><T><T><L><S><P><P><R><H><D><S><L><S><L><D><G><G><T><V><N><P><P><R><V><R><E><P><T><G><R><E><A><F><G><P><S><P><A><S><S><D><W><L><P><A><R><W><R><N><G><R><G><G><R><P><R><A><R><L><C><S><G><W><T><A><A><E><E><A><R><R... | Cytoplasmic isoform that catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.<BOP> | Q9BZ23 |
Q8NH63 | O51H1_HUMAN | Olfactory receptor OR11-25 | Homo | <M><T><N><L><N><A><S><Q><A><N><H><R><N><F><I><L><T><G><I><P><G><T><P><D><K><N><P><W><L><A><F><P><L><G><F><L><Y><T><L><T><L><L><G><N><G><T><I><L><A><V><I><K><V><E><P><S><L><H><E><P><T><Y><Y><F><L><S><I><L><A><L><T><D><V><S><L><S><M><S><T><L><P><S><M><L><S><I><Y><W><F><N><A><P><Q><I><V><F><D><A><C><I><M><Q><M><F><F><I><H... | Odorant receptor.<BOP> | Q8NH63 |
O43680 | TCF21_HUMAN | Podocyte-expressed 1 | Homo | <M><S><T><G><S><L><S><D><V><E><D><L><Q><E><V><E><M><L><E><C><D><G><L><K><M><D><S><N><K><E><F><V><T><S><N><E><S><T><E><E><S><S><N><C><E><N><G><S><P><Q><K><G><R><G><G><L><G><K><R><R><K><A><P><T><K><K><S><P><L><S><G><V><S><Q><E><G><K><Q><V><Q><R><N><A><A><N><A><R><E><R><A><R><M><R><V><L><S><K><A><F><S><R><L><K><T><T><L><P... | Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. May play a role in the specification or differentiation of one or more subsets of epicardial cell types.<BOP> | O43680 |
Q76EJ3 | S35D2_HUMAN | UDP-galactose transporter-related protein 8 | Homo | <M><T><A><G><G><Q><A><E><A><E><G><A><G><G><E><P><G><A><A><R><L><P><S><R><V><A><R><L><L><S><A><L><F><Y><G><T><C><S><F><L><I><V><L><V><N><K><A><L><L><T><T><Y><G><F><P><S><P><I><F><L><G><I><G><Q><M><A><A><T><I><M><I><L><Y><V><S><K><L><N><K><I><I><H><F><P><D><F><D><K><K><I><P><V><K><L><F><P><L><P><L><L><Y><V><G><N><H><I><S... | Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sul... | Q76EJ3 |
O14791 | APOL1_HUMAN | Apolipoprotein L-I | Homo | <M><E><G><A><A><L><L><R><V><S><V><L><C><I><W><M><S><A><L><F><L><G><V><G><V><R><A><E><E><A><G><A><R><V><Q><Q><N><V><P><S><G><T><D><T><G><D><P><Q><S><K><P><L><G><D><W><A><A><G><T><M><D><P><E><S><S><I><F><I><E><D><A><I><K><Y><F><K><E><K><V><S><T><Q><N><L><L><L><L><L><T><D><N><E><A><W><N><G><F><V><A><A><A><E><L><P><R><N><E... | May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.<BOP> | O14791 |
Q96EP9 | NTCP4_HUMAN | Solute carrier family 10 member 4 | Homo | <M><D><G><N><D><N><V><T><L><L><F><A><P><L><L><R><D><N><Y><T><L><A><P><N><A><S><S><L><G><P><G><T><D><L><A><L><A><P><A><S><S><A><G><P><G><P><G><L><S><L><G><P><G><P><S><F><G><F><S><P><G><P><T><P><T><P><E><P><T><T><S><G><L><A><G><G><A><A><S><H><G><P><S><P><F><P><R><P><W><A><P><H><A><L><P><F><W><D><T><P><L><N><H><G><L><N><V... | Transporter for bile acids.<BOP> | Q96EP9 |
Q969Z0 | FAKD4_HUMAN | Transforming growth factor beta regulator 4 | Homo | <M><A><A><H><L><V><K><R><C><T><C><L><L><R><E><A><A><R><Q><A><P><A><M><A><P><V><G><R><L><R><L><A><W><V><A><H><K><T><L><T><S><S><A><T><S><P><I><S><H><L><P><G><S><L><M><E><P><V><E><K><E><R><A><S><T><P><Y><I><E><K><Q><V><D><H><L><I><K><K><A><T><R><P><E><E><L><L><E><L><L><G><G><S><H><D><L><D><S><N><Q><A><A><M><V><L><I><R><L... | Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression .<BOP> | Q969Z0 |
O14713 | ITBP1_HUMAN | Integrin cytoplasmic domain-associated protein 1 | Homo | <M><F><R><K><G><K><K><R><H><S><S><S><S><S><Q><S><S><E><I><S><T><K><S><K><S><V><D><S><S><L><G><G><L><S><R><S><S><T><V><A><S><L><D><T><D><S><T><K><S><S><G><Q><S><N><N><N><S><D><T><C><A><E><F><R><I><K><Y><V><G><A><I><E><K><L><K><L><S><E><G><K><G><L><E><G><P><L><D><L><I><N><Y><I><D><V><A><Q><Q><D><G><K><L><P><F><V><P><P><E... | Key regulator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the co... | O14713 |
P52757 | CHIO_HUMAN | Rho GTPase-activating protein 3 | Homo | <M><A><A><S><S><N><S><S><L><S><G><S><S><V><S><S><D><A><E><E><Y><Q><P><P><I><W><K><S><Y><L><Y><Q><L><Q><Q><E><A><P><R><P><K><R><I><I><C><P><R><E><V><E><N><R><P><K><Y><Y><G><R><E><F><H><G><I><I><S><R><E><Q><A><D><E><L><L><G><G><V><E><G><A><Y><I><L><R><E><S><Q><R><Q><P><G><C><Y><T><L><A><L><R><F><G><N><Q><T><L><N><Y><R><L... | GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.<BOP> | P52757 |
Q96N58 | ZN578_HUMAN | Zinc finger protein 578 | Homo | <M><L><H><E><E><A><A><Q><K><R><K><G><K><E><P><G><M><A><L><P><Q><G><R><L><T><F><R><D><V><A><I><E><F><S><L><A><E><W><K><F><L><N><P><A><Q><R><A><L><Y><R><E><V><M><L><E><N><Y><R><N><L><E><A><V><D><I><S><S><K><R><M><M><K><E><V><L><S><T><G><Q><G><N><T><E><V><I><H><T><G><M><L><Q><R><H><E><S><Y><H><T><G><D><F><C><F><Q><E><I><E... | May be involved in transcriptional regulation.<BOP> | Q96N58 |
Q8NH80 | O10D3_HUMAN | Olfactory receptor OR11-293 | Homo | <M><E><V><K><N><C><C><M><V><T><E><F><I><L><L><G><I><P><H><T><E><G><L><E><M><T><L><F><V><L><F><L><P><F><Y><A><C><T><L><L><G><N><V><S><I><L><V><A><V><M><S><S><A><R><L><H><T><P><M><Y><F><F><L><G><N><L><S><V><F><D><M><G><F><S><S><V><T><C><P><K><M><L><L><Y><L><M><G><L><S><R><L><I><S><Y><K><D><C><V><C><Q><L><F><F><F><H><F><L... | Odorant receptor.<BOP> | Q8NH80 |
Q96PN8 | TSSK3_HUMAN | Serine/threonine-protein kinase 22C | Homo | <M><E><D><F><L><L><S><N><G><Y><Q><L><G><K><T><I><G><E><G><T><Y><S><K><V><K><E><A><F><S><K><K><H><Q><R><K><V><A><I><K><V><I><D><K><M><G><G><P><E><E><F><I><Q><R><F><L><P><R><E><L><Q><I><V><R><T><L><D><H><K><N><I><I><Q><V><Y><E><M><L><E><S><A><D><G><K><I><C><L><V><M><E><L><A><E><G><G><D><V><F><D><C><V><L><N><G><G><P><L><P... | May be involved in a signaling pathway during male germ cell development or mature sperm function.<BOP> | Q96PN8 |
P81277 | PRRP_HUMAN | Prolactin-releasing peptide PrRP20 | Homo | <M><K><V><L><R><A><W><L><L><C><L><L><M><L><G><L><A><L><R><G><A><A><S><R><T><H><R><H><S><M><E><I><R><T><P><D><I><N><P><A><W><Y><A><S><R><G><I><R><P><V><G><R><F><G><R><R><R><A><T><L><G><D><V><P><K><P><G><L><R><P><R><L><T><C><F><P><L><E><G><G><A><M><S><S><Q><D><G> | Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.<BOP> | P81277 |
O75351 | VPS4B_HUMAN | Suppressor of K(+) transport growth defect 1 | Homo | <M><S><S><T><S><P><N><L><Q><K><A><I><D><L><A><S><K><A><A><Q><E><D><K><A><G><N><Y><E><E><A><L><Q><L><Y><Q><H><A><V><Q><Y><F><L><H><V><V><K><Y><E><A><Q><G><D><K><A><K><Q><S><I><R><A><K><C><T><E><Y><L><D><R><A><E><K><L><K><E><Y><L><K><N><K><E><K><K><A><Q><K><P><V><K><E><G><Q><P><S><P><A><D><E><K><G><N><D><S><D><G><E><G><E... | (Microbial infection) In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).<BOP> | O75351 |
Q8IUE0 | TF2LY_HUMAN | TGIF-like on the Y | Homo | <M><E><A><A><A><D><G><P><A><E><T><Q><S><P><V><E><K><D><S><P><A><K><T><Q><S><P><A><Q><D><T><S><I><M><S><R><N><N><A><D><T><G><R><V><L><A><L><P><E><H><K><K><K><R><K><G><N><L><P><A><E><S><V><K><I><L><R><D><W><M><Y><K><H><R><F><K><A><Y><P><S><E><E><E><K><Q><M><L><S><E><K><T><N><L><S><L><L><R><I><S><N><W><F><I><N><A><R><R><R... | May have a transcription role in testis. May act as a competitor/regulator of TGIF2LX.<BOP> | Q8IUE0 |
P19429 | TNNI3_HUMAN | Cardiac troponin I | Homo | <M><A><D><G><S><S><D><A><A><R><E><P><R><P><A><P><A><P><I><R><R><R><S><S><N><Y><R><A><Y><A><T><E><P><H><A><K><K><K><S><K><I><S><A><S><R><K><L><Q><L><K><T><L><L><L><Q><I><A><K><Q><E><L><E><R><E><A><E><E><R><R><G><E><K><G><R><A><L><S><T><R><C><Q><P><L><E><L><A><G><L><G><F><A><E><L><Q><D><L><C><R><Q><L><H><A><R><V><D><K><V... | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.<BOP> | P19429 |
Q6NTE8 | MRNIP_HUMAN | MRN-interacting protein | Homo | <M><A><S><L><Q><R><S><R><V><L><R><C><C><S><C><R><L><F><Q><A><H><Q><V><K><K><S><V><K><W><T><C><K><A><C><G><E><K><Q><S><F><L><Q><A><Y><G><E><G><S><G><A><D><C><R><R><H><V><Q><K><L><N><L><L><Q><G><Q><V><S><E><L><P><L><R><S><L><E><E><T><V><S><A><S><E><E><E><N><V><G><H><Q><Q><A><G><N><V><K><Q><Q><E><K><S><Q><P><S><E><S><R><W... | Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex . Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair .<BOP> | Q6NTE8 |
Q16658 | FSCN1_HUMAN | p55 | Homo | <M><T><A><N><G><T><A><E><A><V><Q><I><Q><F><G><L><I><N><C><G><N><K><Y><L><T><A><E><A><F><G><F><K><V><N><A><S><A><S><S><L><K><K><K><Q><I><W><T><L><E><Q><P><P><D><E><A><G><S><A><A><V><C><L><R><S><H><L><G><R><Y><L><A><A><D><K><D><G><N><V><T><C><E><R><E><V><P><G><P><D><C><R><F><L><I><V><A><H><D><D><G><R><W><S><L><Q><S><E><A... | Actin-binding protein that contains 2 major actin binding sites . Organizes filamentous actin into parallel bundles . Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers . Important for the formation of a diverse set of cell protrusions, such ... | Q16658 |
Q7Z5Y7 | KCD20_HUMAN | Potassium channel tetramerization domain containing 20 | Homo | <M><N><V><H><R><G><S><D><S><D><R><L><L><R><Q><E><A><S><C><L><V><D><D><T><L><A><V><A><Q><E><K><E><A><N><S><L><A><S><S><G><P><H><N><L><T><Y><P><L><G><P><R><N><E><D><L><S><L><D><Y><A><S><Q><P><A><N><L><Q><F><P><H><I><M><P><L><A><E><D><I><K><G><S><C><F><Q><S><G><N><K><R><N><H><E><P><F><I><A><P><E><R><F><G><N><S><S><V><G><F... | Promotes the phosphorylation of AKT family members.<BOP> | Q7Z5Y7 |
P55082 | MFAP3_HUMAN | Microfibril-associated glycoprotein 3 | Homo | <M><K><L><H><C><C><L><F><T><L><V><A><S><I><I><V><P><A><A><F><V><L><E><D><V><D><F><D><Q><M><V><S><L><E><A><N><R><S><S><Y><N><A><S><F><P><S><S><F><E><L><S><A><S><S><H><S><D><D><D><V><I><I><A><K><E><G><T><S><V><S><I><E><C><L><L><T><A><S><H><Y><E><D><V><H><W><H><N><S><K><G><Q><Q><L><D><G><R><S><R><G><G><K><W><L><V><S><D><N... | Component of the elastin-associated microfibrils.<BOP> | P55082 |
Q9BX68 | HINT2_HUMAN | PKCI-1-related HIT protein | Homo | <M><A><A><A><V><V><L><A><A><G><L><R><A><A><R><R><A><V><A><A><T><G><V><R><G><G><Q><V><R><G><A><A><G><V><T><D><G><N><E><V><A><K><A><Q><Q><A><T><P><G><G><A><A><P><T><I><F><S><R><I><L><D><K><S><L><P><A><D><I><L><Y><E><D><Q><Q><C><L><V><F><R><D><V><A><P><Q><A><P><V><H><F><L><V><I><P><K><K><P><I><P><R><I><S><Q><A><E><E><E><D... | Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 . Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) . Hydrolyzes fluorogenic purine nucleoside tryptamine... | Q9BX68 |
Q9Y2C3 | B3GT5_HUMAN | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5 | Homo | <M><A><F><P><K><M><R><L><M><Y><I><C><L><L><V><L><G><A><L><C><L><Y><F><S><M><Y><S><L><N><P><F><K><E><Q><S><F><V><Y><K><K><D><G><N><F><L><K><L><P><D><T><D><C><R><Q><T><P><P><F><L><V><L><L><V><T><S><S><H><K><Q><L><A><E><R><M><A><I><R><Q><T><W><G><K><E><R><M><V><K><G><K><Q><L><K><T><F><F><L><L><G><T><T><S><S><A><A><E><T><K... | Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor.<BOP> | Q9Y2C3 |
P21730 | C5AR1_HUMAN | C5a anaphylatoxin chemotactic receptor | Homo | <M><D><S><F><N><Y><T><T><P><D><Y><G><H><Y><D><D><K><D><T><L><D><L><N><T><P><V><D><K><T><S><N><T><L><R><V><P><D><I><L><A><L><V><I><F><A><V><V><F><L><V><G><V><L><G><N><A><L><V><V><W><V><T><A><F><E><A><K><R><T><I><N><A><I><W><F><L><N><L><A><V><A><D><F><L><S><C><L><A><L><P><I><L><F><T><S><I><V><Q><H><H><H><W><P><F><G><G><A... | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a . The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events . Receptor activation stimulates chemota... | P21730 |
Q8IYL2 | TRM44_HUMAN | Methyltransferase-like protein 19 | Homo | <M><A><E><V><G><R><T><G><I><S><Y><P><G><A><L><L><P><Q><G><F><W><A><A><V><E><V><W><L><E><R><P><Q><V><A><N><K><R><L><C><G><A><R><L><E><A><R><W><S><A><A><L><P><C><A><E><A><R><G><P><G><T><S><A><G><S><E><Q><K><E><R><G><P><G><P><G><Q><G><S><P><G><G><G><P><G><P><R><S><L><S><G><P><E><Q><G><T><A><C><C><E><L><E><E><A><Q><G><Q><C... | Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.<BOP> | Q8IYL2 |
Q8N8R3 | MCATL_HUMAN | Solute carrier family 25 member 29 | Homo | <M><A><L><D><F><L><A><G><C><A><G><G><V><A><G><V><L><V><G><H><P><F><D><T><V><K><V><R><L><Q><V><Q><S><V><E><K><P><Q><Y><R><G><T><L><H><C><F><K><S><I><I><K><Q><E><S><V><L><G><L><Y><K><G><L><G><S><P><L><M><G><L><T><F><I><N><A><L><V><F><G><V><Q><G><N><T><L><R><A><L><G><H><D><S><P><L><N><Q><F><L><A><G><A><A><A><G><A><I><Q><C... | Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine . Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15 . Does not transport carnitine nor acylcarnitines . Functions by both counter-exchange and uniport m... | Q8N8R3 |
Q92882 | OSTF1_HUMAN | Osteoclast-stimulating factor 1 | Homo | <M><S><K><P><P><P><K><P><V><K><P><G><Q><V><K><V><F><R><A><L><Y><T><F><E><P><R><T><P><D><E><L><Y><F><E><E><G><D><I><I><Y><I><T><D><M><S><D><T><N><W><W><K><G><T><S><K><G><R><T><G><L><I><P><S><N><Y><V><A><E><Q><A><E><S><I><D><N><P><L><H><E><A><A><K><R><G><N><L><S><W><L><R><E><C><L><D><N><R><V><G><V><N><G><L><D><K><A><G><S... | Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<BOP> | Q92882 |
Q8N4L4 | SPEM1_HUMAN | Spermatid maturation protein 1 | Homo | <M><A><M><V><E><R><P><R><P><E><W><A><S><Y><H><N><C><N><S><N><S><C><Q><D><L><G><N><S><V><L><L><L><L><G><L><I><I><C><I><N><I><S><I><N><I><V><T><L><L><W><S><R><F><R><G><V><L><Y><Q><V><F><H><D><T><I><C><E><K><E><A><P><K><S><S><L><L><R><K><Q><T><Q><P><P><K><K><Q><S><S><P><A><V><H><L><R><C><T><M><D><P><V><M><M><T><V><S><P><P... | Required for proper cytoplasm removal during spermatogenesis.<BOP> | Q8N4L4 |
Q9BXK5 | B2L13_HUMAN | Protein Mil1 | Homo | <M><A><S><S><S><T><V><P><L><G><F><H><Y><E><T><K><Y><V><V><L><S><Y><L><G><L><L><S><Q><E><K><L><Q><E><Q><H><L><S><S><P><Q><G><V><Q><L><D><I><A><S><Q><S><L><D><Q><E><I><L><L><K><V><K><T><E><I><E><E><E><L><K><S><L><D><K><E><I><S><E><A><F><T><S><T><G><F><D><R><H><T><S><P><V><F><S><P><A><N><P><E><S><S><M><E><D><C><L><A><H><L... | May promote the activation of caspase-3 and apoptosis.<BOP> | Q9BXK5 |
P56278 | MTCP1_HUMAN | Mature T-cell proliferation-1 type B1 | Homo | <M><A><G><E><D><V><G><A><P><P><D><H><L><W><V><H><Q><E><G><I><Y><R><D><E><Y><Q><R><T><W><V><A><V><V><E><E><E><T><S><F><L><R><A><R><V><Q><Q><I><Q><V><P><L><G><D><A><A><R><P><S><H><L><L><T><S><Q><L><P><L><M><W><Q><L><Y><P><E><E><R><Y><M><D><N><N><S><R><L><W><Q><I><Q><H><H><L><M><V><R><G><V><Q><E><L><L><L><K><L><L><P><D><D... | Enhances the phosphorylation and activation of AKT1 and AKT2.<BOP> | P56278 |
Q96LW7 | CAR19_HUMAN | Bcl10-interacting CARD protein | Homo | <M><T><D><Q><T><Y><C><D><R><L><V><Q><D><T><P><F><L><T><G><H><G><R><L><S><E><Q><Q><V><D><R><I><I><L><Q><L><N><R><Y><Y><P><Q><I><L><T><N><K><E><A><E><K><F><R><N><P><K><A><S><L><R><V><R><L><C><D><L><L><S><H><L><Q><R><S><G><E><R><D><C><Q><E><F><Y><R><A><L><Y><I><H><A><Q><P><L><H><S><R><L><P><S><R><H><A><L><R><K><F><H><I><T... | Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.<BOP> | Q96LW7 |
P30711 | GSTT1_HUMAN | Glutathione transferase T1-1 | Homo | <M><G><L><E><L><Y><L><D><L><L><S><Q><P><C><R><A><V><Y><I><F><A><K><K><N><D><I><P><F><E><L><R><I><V><D><L><I><K><G><Q><H><L><S><D><A><F><A><Q><V><N><P><L><K><K><V><P><A><L><K><D><G><D><F><T><L><T><E><S><V><A><I><L><L><Y><L><T><R><K><Y><K><V><P><D><Y><W><Y><P><Q><D><L><Q><A><R><A><R><V><D><E><Y><L><A><W><Q><H><T><T><L><R... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.<BOP> | P30711 |
O00358 | FOXE1_HUMAN | Thyroid transcription factor 2 | Homo | <M><T><A><E><S><G><P><P><P><P><Q><P><E><V><L><A><T><V><K><E><E><R><G><E><T><A><A><G><A><G><V><P><G><E><A><T><G><R><G><A><G><G><R><R><R><K><R><P><L><Q><R><G><K><P><P><Y><S><Y><I><A><L><I><A><M><A><I><A><H><A><P><E><R><R><L><T><L><G><G><I><Y><K><F><I><T><E><R><F><P><F><Y><R><D><N><P><K><K><W><Q><N><S><I><R><H><N><L><T><L... | Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May in... | O00358 |
O60547 | GMDS_HUMAN | GDP-D-mannose dehydratase | Homo | <M><A><H><A><P><A><R><C><P><S><A><R><G><S><G><D><G><E><M><G><K><P><R><N><V><A><L><I><T><G><I><T><G><Q><D><G><S><Y><L><A><E><F><L><L><E><K><G><Y><E><V><H><G><I><V><R><R><S><S><S><F><N><T><G><R><I><E><H><L><Y><K><N><P><Q><A><H><I><E><G><N><M><K><L><H><Y><G><D><L><T><D><S><T><C><L><V><K><I><I><N><E><V><K><P><T><E><I><Y><N... | Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.<BOP> | O60547 |
Q99801 | NKX31_HUMAN | Homeobox protein NK-3 homolog A | Homo | <M><L><R><V><P><E><P><R><P><G><E><A><K><A><E><G><A><A><P><P><T><P><S><K><P><L><T><S><F><L><I><Q><D><I><L><R><D><G><A><Q><R><Q><G><G><R><T><S><S><Q><R><Q><R><D><P><E><P><E><P><E><P><E><P><E><G><G><R><S><R><A><G><A><Q><N><D><Q><L><S><T><G><P><R><A><A><P><E><E><A><E><T><L><A><E><T><E><P><E><R><H><L><G><S><Y><L><L><D><S><E... | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controllin... | Q99801 |
P49721 | PSB2_HUMAN | Proteasome component C7-I | Homo | <M><E><Y><L><I><G><I><Q><G><P><D><Y><V><L><V><A><S><D><R><V><A><A><S><N><I><V><Q><M><K><D><D><H><D><K><M><F><K><M><S><E><K><I><L><L><L><C><V><G><E><A><G><D><T><V><Q><F><A><E><Y><I><Q><K><N><V><Q><L><Y><K><M><R><N><G><Y><E><L><S><P><T><A><A><A><N><F><T><R><R><N><L><A><D><C><L><R><S><R><T><P><Y><H><V><N><L><L><L><A><G><Y... | Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and th... | P49721 |
Q9NRD0 | FBX8_HUMAN | F-box/SEC7 protein FBS | Homo | <M><G><Q><G><L><W><R><V><V><R><N><Q><Q><L><Q><Q><E><G><Y><S><E><Q><G><Y><L><T><R><E><Q><S><R><R><M><A><A><S><N><I><S><N><T><N><H><R><K><Q><V><Q><G><G><I><D><I><Y><H><L><L><K><A><R><K><S><K><E><Q><E><G><F><I><N><L><E><M><L><P><P><E><L><S><F><T><I><L><S><Y><L><N><A><T><D><L><C><L><A><S><C><V><W><Q><D><L><A><N><D><E><L><L... | May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).<BOP> | Q9NRD0 |
Q96PH1 | NOX5_HUMAN | NADPH oxidase 5 | Homo | <M><N><T><S><G><D><P><A><Q><T><G><P><E><G><C><R><G><T><M><S><A><E><E><D><A><R><W><L><R><W><V><T><Q><Q><F><K><T><I><A><G><E><D><G><E><I><S><L><Q><E><F><K><A><A><L><H><V><K><E><S><F><F><A><E><R><F><F><A><L><F><D><S><D><R><S><G><T><I><T><L><Q><E><L><Q><E><A><L><T><L><L><I><H><G><S><P><M><D><K><L><K><F><L><F><Q><V><Y><D><I... | Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen spe... | Q96PH1 |
Q9NQX6 | ZN331_HUMAN | Zinc finger protein 463 | Homo | <M><A><Q><G><L><V><T><F><A><D><V><A><I><D><F><S><Q><E><E><W><A><C><L><N><S><A><Q><R><D><L><Y><W><D><V><M><L><E><N><Y><S><N><L><V><S><L><D><L><E><S><A><Y><E><N><K><S><L><P><T><E><K><N><I><H><E><I><R><A><S><K><R><N><S><D><R><R><S><K><S><L><G><R><N><W><I><C><E><G><T><L><E><R><P><Q><R><S><R><G><R><Y><V><N><Q><M><I><I><N><Y... | May be involved in transcriptional regulation. May play a role in spermatogenesis.<BOP> | Q9NQX6 |
O75940 | SPF30_HUMAN | Survival motor neuron domain-containing protein 1 | Homo | <M><S><E><D><L><A><K><Q><L><A><S><Y><K><A><Q><L><Q><Q><V><E><A><A><L><S><G><N><G><E><N><E><D><L><L><K><L><K><K><D><L><Q><E><V><I><E><L><T><K><D><L><L><S><T><Q><P><S><E><T><L><A><S><S><D><S><F><A><S><T><Q><P><T><H><S><W><K><V><G><D><K><C><M><A><V><W><S><E><D><G><Q><C><Y><E><A><E><I><E><E><I><D><E><E><N><G><T><A><A><I><T... | Involved in spliceosome assembly.<BOP> | O75940 |
Q8TF50 | ZN526_HUMAN | Zinc finger protein 526 | Homo | <M><A><E><V><V><A><E><V><A><E><M><P><T><Q><M><S><P><G><A><V><E><M><S><T><P><M><S><A><E><M><M><E><M><S><T><E><V><T><E><M><T><P><G><E><A><L><A><S><S><L><F><F><Q><H><H><Q><F><M><C><S><E><C><G><S><L><Y><N><T><L><E><E><V><L><S><H><Q><E><Q><H><M><L><A><V><S><E><E><E><A><L><T><T><Q><N><V><G><L><E><P><E><L><V><P><G><A><E><G><P... | May be involved in transcriptional regulation.<BOP> | Q8TF50 |
Q9HB21 | PKHA1_HUMAN | Tandem PH domain-containing protein 1 | Homo | <M><P><Y><V><D><R><Q><N><R><I><C><G><F><L><D><I><E><E><N><E><N><S><G><K><F><L><R><R><Y><F><I><L><D><T><R><E><D><S><F><V><W><Y><M><D><N><P><Q><N><L><P><S><G><S><S><R><V><G><A><I><K><L><T><Y><I><S><K><V><S><D><A><T><K><L><R><P><K><A><E><F><C><F><V><M><N><A><G><M><R><K><Y><F><L><Q><A><N><D><Q><Q><D><L><V><E><W><V><N><V><L... | Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.<BOP> | Q9HB21 |
Q8TCD1 | CR032_HUMAN | Putative NF-kappa-B-activating protein 200 | Homo | <M><V><C><I><P><C><I><V><I><P><V><L><L><W><I><Y><K><K><F><L><E><P><Y><I><Y><P><L><V><S><P><F><V><S><R><I><W><P><K><K><A><I><Q><E><S><N><D><T><N><K><G><K><V><N><F><K><G><A><D><M><N><G><L><P><T><K><G><P><T><E><I><C><D><K><K><K><D> | May activate the NF-kappa-B signaling pathway.<BOP> | Q8TCD1 |
Q8TAX9 | GSDMB_HUMAN | Gasdermin-B, C-terminal | Homo | <M><F><S><V><F><E><E><I><T><R><I><V><V><K><E><M><D><A><G><G><D><M><I><A><V><R><S><L><V><D><A><D><R><F><R><C><F><H><L><V><G><E><K><R><T><F><F><G><C><R><H><Y><T><T><G><L><T><L><M><D><I><L><D><T><D><G><D><K><W><L><D><E><L><D><S><G><L><Q><G><Q><K><A><E><F><Q><I><L><D><N><V><D><S><T><G><E><L><I><V><R><L><P><K><E><I><T><I><S... | Pore-forming protein produced by cleavage by granzyme A (GZMA), which causes membrane permeabilization and pyroptosis in target cells of cytotoxic T and natural killer (NK) cells . Key downstream mediator of granzyme-mediated cell death: (1) granzyme A (GZMA), delivered to target cells from cytotoxic T- and NK-cells, (... | Q8TAX9 |
P60323 | NANO3_HUMAN | Nanos homolog 3 | Homo | <M><G><T><F><D><L><W><T><D><Y><L><G><L><A><H><L><V><R><A><L><S><G><K><E><G><P><E><T><R><L><S><P><Q><P><E><P><E><P><M><L><E><P><D><Q><K><R><S><L><E><S><S><P><A><P><E><R><L><C><S><F><C><K><H><N><G><E><S><R><A><I><Y><Q><S><H><V><L><K><D><E><A><G><R><V><L><C><P><I><L><R><D><Y><V><C><P><Q><C><G><A><T><R><E><R><A><H><T><R><R... | Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -indepe... | P60323 |
P51801 | CLCKB_HUMAN | ClC-K2 | Homo | <M><E><E><F><V><G><L><R><E><G><S><S><G><N><P><V><T><L><Q><E><L><W><G><P><C><P><R><I><R><R><G><I><R><G><G><L><E><W><L><K><Q><K><L><F><R><L><G><E><D><W><Y><F><L><M><T><L><G><V><L><M><A><L><V><S><C><A><M><D><L><A><V><E><S><V><V><R><A><H><Q><W><L><Y><R><E><I><G><D><S><H><L><L><R><Y><L><S><W><T><V><Y><P><V><A><L><V><S><F><S... | Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms.<BOP> | P51801 |
O60563 | CCNT1_HUMAN | Cyclin-T1 | Homo | <M><E><G><E><R><K><N><N><N><K><R><W><Y><F><T><R><E><Q><L><E><N><S><P><S><R><R><F><G><V><D><P><D><K><E><L><S><Y><R><Q><Q><A><A><N><L><L><Q><D><M><G><Q><R><L><N><V><S><Q><L><T><I><N><T><A><I><V><Y><M><H><R><F><Y><M><I><Q><S><F><T><Q><F><P><G><N><S><V><A><P><A><A><L><F><L><A><A><K><V><E><E><Q><P><K><K><L><E><H><V><I><K><V... | (Microbial infection) In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing... | O60563 |
P41217 | OX2G_HUMAN | OX-2 membrane glycoprotein | Homo | <M><E><R><L><V><I><R><M><P><F><S><H><L><S><T><Y><S><L><V><W><V><M><A><A><V><V><L><C><T><A><Q><V><Q><V><V><T><Q><D><E><R><E><Q><L><Y><T><P><A><S><L><K><C><S><L><Q><N><A><Q><E><A><L><I><V><T><W><Q><K><K><K><A><V><S><P><E><N><M><V><T><F><S><E><N><H><G><V><V><I><Q><P><A><Y><K><D><K><I><N><I><T><Q><L><G><L><Q><N><S><T><I><T... | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.<BOP> | P41217 |
P11308 | ERG_HUMAN | Transforming protein ERG | Homo | <M><A><S><T><I><K><E><A><L><S><V><V><S><E><D><Q><S><L><F><E><C><A><Y><G><T><P><H><L><A><K><T><E><M><T><A><S><S><S><S><D><Y><G><Q><T><S><K><M><S><P><R><V><P><Q><Q><D><W><L><S><Q><P><P><A><R><V><T><I><K><M><E><C><N><P><S><Q><V><N><G><S><R><N><S><P><D><E><C><S><V><A><K><G><G><K><M><V><G><S><P><D><T><V><G><M><N><Y><G><S><Y... | Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.<BOP> | P11308 |
Q96G03 | PGM2_HUMAN | Phosphoglucomutase-2 | Homo | <M><A><A><P><E><G><S><G><L><G><E><D><A><R><L><D><Q><E><T><A><Q><W><L><R><W><D><K><N><S><L><T><L><E><A><V><K><R><L><I><A><E><G><N><K><E><E><L><R><K><C><F><G><A><R><M><E><F><G><T><A><G><L><R><A><A><M><G><P><G><I><S><R><M><N><D><L><T><I><I><Q><T><T><Q><G><F><C><R><Y><L><E><K><Q><F><S><D><L><K><Q><K><G><I><V><I><S><F><D><A... | Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. Catalyzes the interconversion of glucose-1-phosphate into glucose-6-phosphate but with a lower catalytic efficiency . In vitro, has also a low glucose 1,6-bisphosphate syn... | Q96G03 |
P14415 | AT1B2_HUMAN | Sodium/potassium-dependent ATPase subunit beta-2 | Homo | <M><V><I><Q><K><E><K><K><S><C><G><Q><V><V><E><E><W><K><E><F><V><W><N><P><R><T><H><Q><F><M><G><R><T><G><T><S><W><A><F><I><L><L><F><Y><L><V><F><Y><G><F><L><T><A><M><F><T><L><T><M><W><V><M><L><Q><T><V><S><D><H><T><P><K><Y><Q><D><R><L><A><T><P><G><L><M><I><R><P><K><T><E><N><L><D><V><I><V><N><V><S><D><T><E><S><W><D><Q><H><V... | Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.<BOP> | P14415 |
P0C7T3 | O56A5_HUMAN | Olfactory receptor 56A5 | Homo | <M><T><L><P><S><N><N><S><T><S><P><V><F><E><F><F><L><I><C><F><P><S><F><Q><S><W><Q><H><W><L><S><L><P><L><S><L><L><F><L><L><A><M><G><A><N><A><T><L><L><I><T><I><Y><L><E><A><S><L><H><Q><P><L><Y><Y><L><L><S><L><L><S><L><L><D><I><V><L><C><L><T><V><I><P><K><V><L><A><I><F><W><F><D><L><R><S><I><S><F><P><A><C><F><L><Q><V><F><I><M... | Odorant receptor.<BOP> | P0C7T3 |
Q969S6 | TM203_HUMAN | Transmembrane protein 203 | Homo | <M><L><F><S><L><R><E><L><V><Q><W><L><G><F><A><T><F><E><I><F><V><H><L><L><A><L><L><V><F><S><V><L><L><A><L><R><V><D><G><L><V><P><G><L><S><W><W><N><V><F><V><P><F><F><A><A><D><G><L><S><T><Y><F><T><T><I><V><S><V><R><L><F><Q><D><G><E><K><R><L><A><V><L><R><L><F><W><V><L><T><V><L><S><L><K><F><V><F><E><M><L><L><C><Q><K><L><A><E... | Involved in the regulation of cellular calcium homeotasis . Required for spermatogenesis .<BOP> | Q969S6 |
P51817 | PRKX_HUMAN | Protein kinase PKX1 | Homo | <M><E><A><P><G><L><A><Q><A><A><A><A><E><S><D><S><R><K><V><A><E><E><T><P><D><G><A><P><A><L><C><P><S><P><E><A><L><S><P><E><P><P><V><Y><S><L><Q><D><F><D><T><L><A><T><V><G><T><G><T><F><G><R><V><H><L><V><K><E><K><T><A><K><H><F><F><A><L><K><V><M><S><I><P><D><V><I><R><L><K><Q><E><Q><H><V><H><N><E><K><S><V><L><K><E><V><S><H><P... | Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphory... | P51817 |
Q9BYR3 | KRA44_HUMAN | Ultrahigh sulfur keratin-associated protein 4.4 | Homo | <M><V><N><S><C><C><G><S><V><C><S><D><Q><G><C><G><L><E><N><C><C><R><P><S><Y><C><Q><T><T><C><C><R><T><T><C><C><R><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><T><T><C><C><R><T><T><C><C><H><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><S><V><C><C><Q><P><T><C><C><R><P><Q><C><C><Q><T><T><C><C><R><T><T><C><C><R><P><S><C><C><R... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BYR3 |
Q96K30 | RITA1_HUMAN | RBPJ-interacting and tubulin-associated protein | Homo | <M><K><T><P><V><E><L><A><V><S><G><M><Q><T><L><G><L><Q><H><R><C><R><G><G><Y><R><V><K><A><R><T><S><Y><V><D><E><T><L><F><G><S><P><A><G><T><R><P><T><P><P><D><F><D><P><P><W><V><E><K><A><N><R><T><R><G><V><G><K><E><A><S><K><A><L><G><A><K><G><S><C><E><T><T><P><S><R><G><S><T><P><T><L><T><P><R><K><K><N><K><Y><R><P><I><S><H><T><P... | Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-reg... | Q96K30 |
Q15910 | EZH2_HUMAN | Lysine N-methyltransferase 6 | Homo | <M><G><Q><T><G><K><K><S><E><K><G><P><V><C><W><R><K><R><V><K><S><E><Y><M><R><L><R><Q><L><K><R><F><R><R><A><D><E><V><K><S><M><F><S><S><N><R><Q><K><I><L><E><R><T><E><I><L><N><Q><E><W><K><Q><R><R><I><Q><P><V><H><I><L><T><S><V><S><S><L><R><G><T><R><E><C><S><V><T><S><D><L><D><F><P><T><Q><V><I><P><L><K><T><L><N><A><V><A><S><V... | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, res... | Q15910 |
Q6E0U4 | DMKN_HUMAN | null | Homo | <M><K><F><Q><G><P><L><A><C><L><L><L><A><L><C><L><G><S><G><E><A><G><P><L><Q><S><G><E><E><S><T><G><T><N><I><G><E><A><L><G><H><G><L><G><D><A><L><S><E><G><V><G><K><A><I><G><K><E><A><G><G><A><A><G><S><K><V><S><E><A><L><G><Q><G><T><R><E><A><V><G><T><G><V><R><Q><V><P><G><F><G><V><A><D><A><L><G><N><R><V><G><E><A><A><H><A><L><G... | May act as a soluble regulator of keratinocyte differentiation.<BOP> | Q6E0U4 |
Q5W5W9 | RES18_HUMAN | Regulated endocrine-specific protein 18 | Homo | <M><A><V><D><V><E><F><G><V><A><G><W><W><E><A><A><A><P><L><S><P><S><A><V><A><A><T><F><T><E><T><W><P><G><S><E><R><A><E><P><G><R><I><Q><H><P><L><W><P><G><S><S><E><G><L><Q><L><L><V><C><F><L><L><L><N><S><C><P><G><G><C><S><D><T><S><A><H><D><G><Q><D><Q><V><G><V><G><Q><L><W><P><L><Q><G><F><A><T><P><V><F><Q><H><L><Q><V><V><L><Q... | May play an important regulatory role in corticotrophs.<BOP> | Q5W5W9 |
O14625 | CXL11_HUMAN | Small-inducible cytokine B11 | Homo | <M><S><V><K><G><M><A><I><A><L><A><V><I><L><C><A><T><V><V><Q><G><F><P><M><F><K><R><G><R><C><L><C><I><G><P><G><V><K><A><V><K><V><A><D><I><E><K><A><S><I><M><Y><P><S><N><N><C><D><K><I><E><V><I><I><T><L><K><E><N><K><G><Q><R><C><L><N><P><K><S><K><Q><A><R><L><I><I><K><K><V><E><R><K><N><F> | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.<BOP> | O14625 |
P01303 | NPY_HUMAN | C-flanking peptide of NPY | Homo | <M><L><G><N><K><R><L><G><L><S><G><L><T><L><A><L><S><L><L><V><C><L><G><A><L><A><E><A><Y><P><S><K><P><D><N><P><G><E><D><A><P><A><E><D><M><A><R><Y><Y><S><A><L><R><H><Y><I><N><L><I><T><R><Q><R><Y><G><K><R><S><S><P><E><T><L><I><S><D><L><L><M><R><E><S><T><E><N><V><P><R><T><R><L><E><D><P><A><M><W> | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.<BOP> | P01303 |
P24666 | PPAC_HUMAN | Red cell acid phosphatase 1 | Homo | <M><A><E><Q><A><T><K><S><V><L><F><V><C><L><G><N><I><C><R><S><P><I><A><E><A><V><F><R><K><L><V><T><D><Q><N><I><S><E><N><W><R><V><D><S><A><A><T><S><G><Y><E><I><G><N><P><P><D><Y><R><G><Q><S><C><M><K><R><H><G><I><P><M><S><H><V><A><R><Q><I><T><K><E><D><F><A><T><F><D><Y><I><L><C><M><D><E><S><N><L><R><D><L><N><R><K><S><N><Q><V... | Does not possess phosphatase activity.<BOP> | P24666 |
Q96P69 | GPR78_HUMAN | G-protein coupled receptor 78 | Homo | <M><G><P><G><E><A><L><L><A><G><L><L><V><M><V><L><A><V><A><L><L><S><N><A><L><V><L><L><C><C><A><Y><S><A><E><L><R><T><R><A><S><G><V><L><L><V><N><L><S><L><G><H><L><L><L><A><A><L><D><M><P><F><T><L><L><G><V><M><R><G><R><T><P><S><A><P><G><A><C><Q><V><I><G><F><L><D><T><F><L><A><S><N><A><A><L><S><V><A><A><L><S><A><D><Q><W><L><A... | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.<BOP> | Q96P69 |
A1KXE4 | F168B_HUMAN | p20 | Homo | <M><N><P><V><Y><S><P><G><S><S><G><V><P><Y><A><N><A><K><G><I><G><Y><P><A><G><F><P><M><G><Y><A><A><A><A><P><A><Y><S><P><N><M><Y><P><G><A><N><P><T><F><Q><T><G><Y><T><P><G><T><P><Y><K><V><S><C><S><P><T><S><G><A><V><P><P><Y><S><S><S><P><N><P><Y><Q><T><A><V><Y><P><V><R><S><A><Y><P><Q><Q><S><P><Y><A><Q><Q><G><T><Y><Y><T><Q><P... | Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC27.<BOP> | A1KXE4 |
Q8NH70 | O4A16_HUMAN | Olfactory receptor OR11-117 | Homo | <M><R><P><S><S><N><V><T><E><F><V><L><L><G><L><T><Q><D><P><D><V><K><K><T><L><F><V><M><F><L><L><I><Y><I><V><T><M><V><G><N><L><L><I><W><V><T><T><I><G><S><P><S><L><G><S><L><M><Y><F><F><L><A><Y><L><S><L><M><D><A><I><Y><S><T><A><M><S><P><K><L><M><I><D><L><L><C><D><K><I><A><I><S><L><S><A><C><M><G><Q><L><F><I><E><H><L><L><G><G... | Odorant receptor.<BOP> | Q8NH70 |
Q6ZV50 | RFX8_HUMAN | Regulatory factor X 8 | Homo | <M><A><E><G><V><P><A><S><P><S><S><G><E><G><S><R><G><P><H><S><G><V><I><Q><W><L><V><D><N><F><C><I><C><E><E><C><S><V><P><R><C><L><M><Y><E><I><Y><V><E><T><C><G><Q><N><T><E><N><Q><V><N><P><A><T><F><G><K><L><V><R><L><V><F><P><D><L><G><T><R><R><L><G><T><R><G><S><A><R><Y><H><Y><D><G><I><C><I><K><K><S><S><F><F><Y><A><Q><Y><C><Y... | May be a transcription factor.<BOP> | Q6ZV50 |
O95336 | 6PGL_HUMAN | 6-phosphogluconolactonase | Homo | <M><A><A><P><A><P><G><L><I><S><V><F><S><S><S><Q><E><L><G><A><A><L><A><Q><L><V><A><Q><R><A><A><C><C><L><A><G><A><R><A><R><F><A><L><G><L><S><G><G><S><L><V><S><M><L><A><R><E><L><P><A><A><V><A><P><A><G><P><A><S><L><A><R><W><T><L><G><F><C><D><E><R><L><V><P><F><D><H><A><E><S><T><Y><G><L><Y><R><T><H><L><L><S><R><L><P><I><P><E... | Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.<BOP> | O95336 |
A0A0K0K1E9 | TVB77_HUMAN | T cell receptor beta variable 7-7 | Homo | <M><G><T><S><L><L><C><W><V><V><L><G><F><L><G><T><D><H><T><G><A><G><V><S><Q><S><P><R><Y><K><V><T><K><R><G><Q><D><V><T><L><R><C><D><P><I><S><S><H><A><T><L><Y><W><Y><Q><Q><A><L><G><Q><G><P><E><F><L><T><Y><F><N><Y><E><A><Q><P><D><K><S><G><L><P><S><D><R><F><S><A><E><R><P><E><G><S><I><S><T><L><T><I><Q><R><T><E><Q><R><D><S><A... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0K0K1E9 |
Q8TCW9 | PKR1_HUMAN | GPR73a | Homo | <M><E><T><T><M><G><F><M><D><D><N><A><T><N><T><S><T><S><F><L><S><V><L><N><P><H><G><A><H><A><T><S><F><P><F><N><F><S><Y><S><D><Y><D><M><P><L><D><E><D><E><D><V><T><N><S><R><T><F><F><A><A><K><I><V><I><G><M><A><L><V><G><I><M><L><V><C><G><I><G><N><F><I><F><I><A><A><L><V><R><Y><K><K><L><R><N><L><T><N><L><L><I><A><N><L><A><I><S... | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.<BOP> | Q8TCW9 |
Q8N7H5 | PAF1_HUMAN | Pancreatic differentiation protein 2 | Homo | <M><A><P><T><I><Q><T><Q><A><Q><R><E><D><G><H><R><P><N><S><H><R><T><L><P><E><R><S><G><V><V><C><R><V><K><Y><C><N><S><L><P><D><I><P><F><D><P><K><F><I><T><Y><P><F><D><Q><N><R><F><V><Q><Y><K><A><T><S><L><E><K><Q><H><K><H><D><L><L><T><E><P><D><L><G><V><T><I><D><L><I><N><P><D><T><Y><R><I><D><P><N><V><L><L><D><P><A><D><E><K><L... | Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and... | Q8N7H5 |
Q7L5D6 | GET4_HUMAN | Transmembrane domain recognition complex 35 kDa subunit | Homo | <M><A><A><A><A><A><M><A><E><Q><E><S><A><R><N><G><G><R><N><R><G><G><V><Q><R><V><E><G><K><L><R><A><S><V><E><K><G><D><Y><Y><E><A><H><Q><M><Y><R><T><L><F><F><R><Y><M><S><Q><S><K><H><T><E><A><R><E><L><M><Y><S><G><A><L><L><F><F><S><H><G><Q><Q><N><S><A><A><D><L><S><M><L><V><L><E><S><L><E><K><A><E><V><E><V><A><D><E><L><L><E><N... | As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degrada... | Q7L5D6 |
A0A0C4DH25 | KVD20_HUMAN | Immunoglobulin kappa variable 3D-20 | Homo | <M><E><T><P><A><Q><L><L><F><L><L><L><L><W><L><P><D><T><T><G><E><I><V><L><T><Q><S><P><A><T><L><S><L><S><P><G><E><R><A><T><L><S><C><G><A><S><Q><S><V><S><S><S><Y><L><A><W><Y><Q><Q><K><P><G><L><A><P><R><L><L><I><Y><D><A><S><S><R><A><T><G><I><P><D><R><F><S><G><S><G><S><G><T><D><F><T><L><T><I><S><R><L><E><P><E><D><F><A><V><Y... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0C4DH25 |
Q96FC7 | PHIPL_HUMAN | Phytanoyl-CoA hydroxylase-interacting protein-like | Homo | <M><E><V><P><R><L><D><H><A><L><N><S><P><T><S><P><C><E><E><V><I><K><N><L><S><L><E><A><I><Q><L><C><D><R><D><G><N><K><S><Q><D><S><G><I><A><E><M><E><E><L><P><V><P><H><N><I><K><I><S><N><I><T><C><D><S><F><K><I><S><W><E><M><D><S><K><S><K><D><R><I><T><H><Y><F><I><D><L><N><K><K><E><N><K><N><S><N><K><F><K><H><K><D><V><P><T><K><L... | May play a role in the development of the central system.<BOP> | Q96FC7 |
P34998 | CRFR1_HUMAN | Corticotropin-releasing hormone receptor 1 | Homo | <M><G><G><H><P><Q><L><R><L><V><K><A><L><L><L><L><G><L><N><P><V><S><A><S><L><Q><D><Q><H><C><E><S><L><S><L><A><S><N><I><S><G><L><Q><C><N><A><S><V><D><L><I><G><T><C><W><P><R><S><P><A><G><Q><L><V><V><R><P><C><P><A><F><F><Y><G><V><R><Y><N><T><T><N><N><G><Y><R><E><C><L><A><N><G><S><W><A><A><R><V><N><Y><S><E><C><Q><E><I><L><N... | G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activati... | P34998 |
P53634 | CATC_HUMAN | Dipeptidyl peptidase I light chain | Homo | <M><G><A><G><P><S><L><L><L><A><A><L><L><L><L><L><S><G><D><G><A><V><R><C><D><T><P><A><N><C><T><Y><L><D><L><L><G><T><W><V><F><Q><V><G><S><S><G><S><Q><R><D><V><N><C><S><V><M><G><P><Q><E><K><K><V><V><V><Y><L><Q><K><L><D><T><A><Y><D><D><L><G><N><S><G><H><F><T><I><I><Y><N><Q><G><F><E><I><V><L><N><D><Y><K><W><F><A><F><F><K><Y... | Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serin... | P53634 |
Q8IVC4 | ZN584_HUMAN | Zinc finger protein 584 | Homo | <M><A><G><E><A><E><A><Q><L><D><P><S><L><Q><G><L><V><M><F><E><D><V><T><V><Y><F><S><R><E><E><W><G><L><L><N><V><T><Q><K><G><L><Y><R><D><V><M><L><E><N><F><A><L><V><S><S><L><G><L><A><P><S><R><S><P><V><F><T><Q><L><E><D><D><E><Q><S><W><V><P><S><W><V><D><V><T><P><V><S><R><A><E><A><R><R><G><F><G><L><D><G><L><C><R><V><E><D><E><R... | May be involved in transcriptional regulation.<BOP> | Q8IVC4 |
Q9UK17 | KCND3_HUMAN | Voltage-gated potassium channel subunit Kv4.3 | Homo | <M><A><A><G><V><A><A><W><L><P><F><A><R><A><A><A><I><G><W><M><P><V><A><N><C><P><M><P><L><A><P><A><D><K><N><K><R><Q><D><E><L><I><V><L><N><V><S><G><R><R><F><Q><T><W><R><T><T><L><E><R><Y><P><D><T><L><L><G><S><T><E><K><E><F><F><F><N><E><D><T><K><E><Y><F><F><D><R><D><P><E><V><F><R><C><V><L><N><F><Y><R><T><G><K><L><H><Y><P><R... | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.<BOP> | Q9UK17 |
Q9Y3X0 | CCDC9_HUMAN | Coiled-coil domain-containing protein 9 | Homo | <M><A><A><T><L><D><L><K><S><K><E><E><K><D><A><E><L><D><K><R><I><E><A><L><R><R><K><N><E><A><L><I><R><R><Y><Q><E><I><E><E><D><R><K><K><A><E><L><E><G><V><A><V><T><A><P><R><K><G><R><S><V><E><K><E><N><V><A><V><E><S><E><K><N><L><G><P><S><R><R><S><P><G><T><P><R><P><P><G><A><S><K><G><G><R><T><P><P><Q><Q><G><G><R><A><G><M><G><R... | Probable component of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-media... | Q9Y3X0 |
P56470 | LEG4_HUMAN | Lactose-binding lectin 4 | Homo | <M><A><Y><V><P><A><P><G><Y><Q><P><T><Y><N><P><T><L><P><Y><Y><Q><P><I><P><G><G><L><N><V><G><M><S><V><Y><I><Q><G><V><A><S><E><H><M><K><R><F><F><V><N><F><V><V><G><Q><D><P><G><S><D><V><A><F><H><F><N><P><R><F><D><G><W><D><K><V><V><F><N><T><L><Q><G><G><K><W><G><S><E><E><R><K><R><S><M><P><F><K><K><G><A><A><F><E><L><V><F><I><V... | Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.<BOP> | P56470 |
Q8NGL2 | OR5L1_HUMAN | Olfactory receptor OR11-151 | Homo | <M><G><K><E><N><C><T><T><V><A><E><F><I><L><L><G><L><S><D><V><P><E><L><R><V><C><L><F><L><L><F><L><L><I><Y><G><V><T><L><L><A><N><L><G><M><I><A><L><I><Q><V><S><S><R><L><H><T><P><M><Y><F><F><L><S><H><L><S><S><V><D><F><C><Y><S><S><I><I><V><P><K><M><L><A><N><I><F><N><K><D><K><A><I><S><F><L><G><C><M><V><Q><F><Y><L><F><C><T><C... | Odorant receptor.<BOP> | Q8NGL2 |
P13010 | XRCC5_HUMAN | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | Homo | <M><V><R><S><G><N><K><A><A><V><V><L><C><M><D><V><G><F><T><M><S><N><S><I><P><G><I><E><S><P><F><E><Q><A><K><K><V><I><T><M><F><V><Q><R><Q><V><F><A><E><N><K><D><E><I><A><L><V><L><F><G><T><D><G><T><D><N><P><L><S><G><G><D><Q><Y><Q><N><I><T><V><H><R><H><L><M><L><P><D><F><D><L><L><E><D><I><E><S><K><I><Q><P><G><S><Q><Q><A><D><F... | Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA . Required for double-strand break repair and V(D)J recombination . Also has a role in chromosome translocation . The DNA helicase II complex binds preferentially to fork-like ... | P13010 |
O15431 | COPT1_HUMAN | Solute carrier family 31 member 1 | Homo | <M><D><H><S><H><H><M><G><M><S><Y><M><D><S><N><S><T><M><Q><P><S><H><H><H><P><T><T><S><A><S><H><S><H><G><G><G><D><S><S><M><M><M><M><P><M><T><F><Y><F><G><F><K><N><V><E><L><L><F><S><G><L><V><I><N><T><A><G><E><M><A><G><A><F><V><A><V><F><L><L><A><M><F><Y><E><G><L><K><I><A><R><E><S><L><L><R><K><S><Q><V><S><I><R><Y><N><S><M><P... | High-affinity, saturable copper transporter involved in dietary copper uptake.<BOP> | O15431 |
Q96IZ5 | RBM41_HUMAN | RNA-binding motif protein 41 | Homo | <M><K><R><V><N><S><C><V><K><S><D><E><H><V><L><E><E><L><E><T><E><G><E><R><Q><L><K><S><L><L><Q><H><Q><L><D><T><S><V><S><I><E><E><C><M><S><K><K><E><S><F><A><P><G><T><M><Y><K><P><F><G><K><E><A><A><G><T><M><T><L><S><Q><F><Q><T><L><H><E><K><D><Q><E><T><A><S><L><R><E><L><G><L><N><E><T><E><I><L><I><W><K><S><H><V><S><G><E><K><K... | May bind RNA.<BOP> | Q96IZ5 |
Q0GE19 | NTCP7_HUMAN | Solute carrier family 10 member 7 | Homo | <M><R><L><L><E><R><M><R><K><D><W><F><M><V><G><I><V><L><A><I><A><G><A><K><L><E><P><S><I><G><V><N><G><G><P><L><K><P><E><I><T><V><S><Y><I><A><V><A><T><I><F><F><N><S><G><L><S><L><K><T><E><E><L><T><S><A><L><V><H><L><K><L><H><L><F><I><Q><I><F><T><L><A><F><F><P><A><T><I><W><L><F><L><Q><L><L><S><I><T><P><I><N><E><W><L><L><K><G... | Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization . Also involved in the regulation of cellular calcium homeostasis . Does n... | Q0GE19 |
Q8IWW8 | HOT_HUMAN | Fe-containing alcohol dehydrogenase | Homo | <M><A><A><A><A><R><A><R><V><A><Y><L><L><R><Q><L><Q><R><A><A><C><Q><C><P><T><H><S><H><T><Y><S><Q><A><P><G><L><S><P><S><G><K><T><T><D><Y><A><F><E><M><A><V><S><N><I><R><Y><G><A><A><V><T><K><E><V><G><M><D><L><K><N><M><G><A><K><N><V><C><L><M><T><D><K><N><L><S><K><L><P><P><V><Q><V><A><M><D><S><L><V><K><N><G><I><P><F><T><V><Y... | Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.<BOP... | Q8IWW8 |
Q9NTW7 | ZF64B_HUMAN | Zinc finger protein 338 | Homo | <M><N><A><S><S><E><G><E><S><F><A><G><S><V><Q><I><P><G><G><T><T><V><L><V><E><L><T><P><D><I><H><I><C><G><I><C><K><Q><Q><F><N><N><L><D><A><F><V><A><H><K><Q><S><G><C><Q><L><T><G><T><S><A><A><A><P><S><T><V><Q><F><V><S><E><E><T><V><P><A><T><Q><T><Q><T><T><T><R><T><I><T><S><E><T><Q><T><I><T><V><S><A><P><E><F><V><F><E><H><G><Y... | May be involved in the regulation of mesenchymal cell differentiation through transactivation of NOTCH1 target genes.<BOP> | Q9NTW7 |
Q9BRQ8 | FSP1_HUMAN | p53-responsive gene 3 protein | Homo | <M><G><S><Q><V><S><V><E><S><G><A><L><H><V><V><I><V><G><G><G><F><G><G><I><A><A><A><S><Q><L><Q><A><L><N><V><P><F><M><L><V><D><M><K><D><S><F><H><H><N><V><A><A><L><R><A><S><V><E><T><G><F><A><K><K><T><F><I><S><Y><S><V><T><F><K><D><N><F><R><Q><G><L><V><V><G><I><D><L><K><N><Q><M><V><L><L><Q><G><G><E><A><L><P><F><S><H><L><I><L... | A NAD(P)H-dependent oxidoreductase involved in cellular oxidative stress response. At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis. Cooperates with GPX4 to suppress phosph... | Q9BRQ8 |
Q8IYA8 | IHO1_HUMAN | Coiled-coil domain-containing protein 36 | Homo | <M><N><F><N><V><W><N><I><K><E><M><L><S><I><P><S><G><S><G><N><K><K><S><S><N><W><N><N><N><Q><N><D><Y><S><S><L><S><D><S><Q><F><L><F><G><S><Q><F><C><P><E><N><S><E><T><L><S><A><P><L><D><F><G><A><H><L><R><H><S><K><Q><S><Q><Q><N><Y><L><E><G><E><P><S><I><F><T><K><Y><Q><T><K><P><Q><L><F><G><G><D><I><K><D><G><G><L><F><P><P><P><L... | Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-inde... | Q8IYA8 |
Q8NFZ8 | CADM4_HUMAN | TSLC1-like protein 2 | Homo | <M><G><R><A><R><R><F><Q><W><P><L><L><L><L><W><A><A><A><A><G><P><G><A><G><Q><E><V><Q><T><E><N><V><T><V><A><E><G><G><V><A><E><I><T><C><R><L><H><Q><Y><D><G><S><I><V><V><I><Q><N><P><A><R><Q><T><L><F><F><N><G><T><R><A><L><K><D><E><R><F><Q><L><E><E><F><S><P><R><R><V><R><I><R><L><S><D><A><R><L><E><D><E><G><G><Y><F><C><Q><L><Y... | Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.<BOP> | Q8NFZ8 |
Q9Y2Y8 | PRG3_HUMAN | Prepro-major basic protein homolog | Homo | <M><Q><C><L><L><L><L><P><F><L><L><L><G><T><V><S><A><L><H><L><E><N><D><A><P><H><L><E><S><L><E><T><Q><A><D><L><G><Q><D><L><D><S><S><K><E><Q><E><R><D><L><A><L><T><E><E><V><I><Q><A><E><G><E><E><V><K><A><S><A><C><Q><D><N><F><E><D><E><E><A><M><E><S><D><P><A><A><L><D><K><D><F><Q><C><P><R><E><E><D><I><V><E><V><Q><G><S><P><R><C... | Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.<BOP> | Q9Y2Y8 |
O15467 | CCL16_HUMAN | Small-inducible cytokine A16 | Homo | <M><K><V><S><E><A><A><L><S><L><L><V><L><I><L><I><I><T><S><A><S><R><S><Q><P><K><V><P><E><W><V><N><T><P><S><T><C><C><L><K><Y><Y><E><K><V><L><P><R><R><L><V><V><G><Y><R><K><A><L><N><C><H><L><P><A><I><I><F><V><T><K><R><N><R><E><V><C><T><N><P><N><D><D><W><V><Q><E><Y><I><K><D><P><N><L><P><L><L><P><T><R><N><L><S><T><V><K><I><I... | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a cal... | O15467 |
O15062 | ZBTB5_HUMAN | Zinc finger and BTB domain-containing protein 5 | Homo | <M><D><F><P><G><H><F><E><Q><I><F><Q><Q><L><N><Y><Q><R><L><H><G><Q><L><C><D><C><V><I><V><V><G><N><R><H><F><K><A><H><R><S><V><L><A><A><C><S><T><H><F><R><A><L><F><S><V><A><E><G><D><Q><T><M><N><M><I><Q><L><D><S><E><V><V><T><A><E><A><F><A><A><L><I><D><M><M><Y><T><S><T><L><M><L><G><E><S><N><V><M><D><V><L><L><A><A><S><H><L><H... | May be involved in transcriptional regulation.<BOP> | O15062 |
Q96A28 | SLAF9_HUMAN | CD84 homolog 1 | Homo | <M><C><A><F><P><W><L><L><L><L><L><L><L><Q><E><G><S><Q><R><R><L><W><R><W><C><G><S><E><E><V><V><A><V><L><Q><E><S><I><S><L><P><L><E><I><P><P><D><E><E><V><E><N><I><I><W><S><S><H><K><S><L><A><T><V><V><P><G><K><E><G><H><P><A><T><I><M><V><T><N><P><H><Y><Q><G><Q><V><S><F><L><D><P><S><Y><S><L><H><I><S><N><L><S><W><E><D><S><G><L... | May play a role in the immune response.<BOP> | Q96A28 |
Q8NH69 | OR5W2_HUMAN | Olfactory receptor OR11-155 | Homo | <M><D><W><E><N><C><S><S><L><T><D><F><F><L><L><G><I><T><N><N><P><E><M><K><V><T><L><F><A><V><F><L><A><V><Y><I><I><N><F><S><A><N><L><G><M><I><V><L><I><R><M><D><Y><Q><L><H><T><P><M><Y><F><F><L><S><H><L><S><F><C><D><L><C><Y><S><T><A><T><G><P><K><M><L><V><D><L><L><A><K><N><K><S><I><P><F><Y><G><C><A><L><Q><F><L><V><F><C><I><F... | Odorant receptor.<BOP> | Q8NH69 |
Q9H237 | PORCN_HUMAN | Protein MG61 | Homo | <M><A><T><F><S><R><Q><E><F><F><Q><Q><L><L><Q><G><C><L><L><P><T><A><Q><Q><G><L><D><Q><I><W><L><L><L><A><I><C><L><A><C><R><L><L><W><R><L><G><L><P><S><Y><L><K><H><A><S><T><V><A><G><G><F><F><S><L><Y><H><F><F><Q><L><H><M><V><W><V><V><L><L><S><L><L><C><Y><L><V><L><F><L><C><R><H><S><S><H><R><G><V><F><L><S><V><T><I><L><I><Y><L... | Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.<BOP> | Q9H237 |
Q9H173 | SIL1_HUMAN | BiP-associated protein | Homo | <M><A><P><Q><S><L><P><S><S><R><M><A><P><L><G><M><L><L><G><L><L><M><A><A><C><F><T><F><C><L><S><H><Q><N><L><K><E><F><A><L><T><N><P><E><K><S><S><T><K><E><T><E><R><K><E><T><K><A><E><E><E><L><D><A><E><V><L><E><V><F><H><P><T><H><E><W><Q><A><L><Q><P><G><Q><A><V><P><A><G><S><H><V><R><L><N><L><Q><T><G><E><R><E><A><K><L><Q><Y><E... | Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.<BOP> | Q9H173 |
O14764 | GBRD_HUMAN | GABA(A) receptor subunit delta | Homo | <M><D><A><P><A><R><L><L><A><P><L><L><L><L><C><A><Q><Q><L><R><G><T><R><A><M><N><D><I><G><D><Y><V><G><S><N><L><E><I><S><W><L><P><N><L><D><G><L><I><A><G><Y><A><R><N><F><R><P><G><I><G><G><P><P><V><N><V><A><L><A><L><E><V><A><S><I><D><H><I><S><E><A><N><M><E><Y><T><M><T><V><F><L><H><Q><S><W><R><D><S><R><L><S><Y><N><H><T><N><E... | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.<BOP> | O14764 |
Q2TAA5 | ALG11_HUMAN | Glycolipid 2-alpha-mannosyltransferase | Homo | <M><A><A><G><E><R><S><W><C><L><C><K><L><L><R><F><F><Y><S><L><F><F><P><G><L><I><V><C><G><T><L><C><V><C><L><V><I><V><L><W><G><I><R><L><L><L><Q><R><K><K><K><L><V><S><T><S><K><N><G><K><N><Q><M><V><I><A><F><F><H><P><Y><C><N><A><G><G><G><G><E><R><V><L><W><C><A><L><R><A><L><Q><K><K><Y><P><E><A><V><Y><V><V><Y><T><G><D><V><N><V... | Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.<BOP> | Q2TAA5 |
Q03405 | UPAR_HUMAN | Monocyte activation antigen Mo3 | Homo | <M><G><H><P><P><L><L><P><L><L><L><L><L><H><T><C><V><P><A><S><W><G><L><R><C><M><Q><C><K><T><N><G><D><C><R><V><E><E><C><A><L><G><Q><D><L><C><R><T><T><I><V><R><L><W><E><E><G><E><E><L><E><L><V><E><K><S><C><T><H><S><E><K><T><N><R><T><L><S><Y><R><T><G><L><K><I><T><S><L><T><E><V><V><C><G><L><D><L><C><N><Q><G><N><S><G><R><A><V... | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.<BOP> | Q03405 |
A6NLW8 | DUXA_HUMAN | Double homeobox protein A | Homo | <M><A><E><D><T><Y><S><H><K><M><V><K><T><N><H><R><R><C><R><T><K><F><T><E><E><Q><L><K><I><L><I><N><T><F><N><Q><K><P><Y><P><G><Y><A><T><K><Q><K><L><A><L><E><I><N><T><E><E><S><R><I><Q><I><W><F><Q><N><R><R><A><R><H><G><F><Q><K><R><P><E><A><E><T><L><E><S><S><Q><S><Q><G><Q><D><Q><P><G><V><E><F><Q><S><R><E><A><R><R><C><R><T><T... | Transcription factor that acts as repressor.<BOP> | A6NLW8 |
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