accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q86X83 | COMD2_HUMAN | COMM domain-containing protein 2 | Homo | <M><L><L><E><L><S><E><E><H><K><E><H><L><A><F><L><P><Q><V><D><S><A><V><V><A><E><F><G><R><I><A><V><E><F><L><R><R><G><A><N><P><K><I><Y><E><G><A><A><R><K><L><N><V><S><S><D><T><V><Q><H><G><V><E><G><L><T><Y><L><L><T><E><S><S><K><L><M><I><S><E><L><D><F><Q><D><S><V><F><V><L><G><F><S><E><E><L><N><K><L><L><L><Q><L><Y><L><D><N><R... | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes . May down-regulate activation of NF-kappa-B .<BOP> | Q86X83 |
O76096 | CYTF_HUMAN | Leukocystatin | Homo | <M><R><A><A><G><T><L><L><A><F><C><C><L><V><L><S><T><T><G><G><P><S><P><D><T><C><S><Q><D><L><N><S><R><V><K><P><G><F><P><K><T><I><K><T><N><D><P><G><V><L><Q><A><A><R><Y><S><V><E><K><F><N><N><C><T><N><D><M><F><L><F><K><E><S><R><I><T><R><A><L><V><Q><I><V><K><G><L><K><Y><M><L><E><V><E><I><G><R><T><T><C><K><K><N><Q><H><L><R><L... | Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.<BOP> | O76096 |
P49795 | RGS19_HUMAN | G-alpha-interacting protein | Homo | <M><P><T><P><H><E><A><E><K><Q><I><T><G><P><E><E><A><D><R><P><P><S><M><S><S><H><D><T><A><S><P><A><A><P><S><R><N><P><C><C><L><C><W><C><C><C><C><S><C><S><W><N><Q><E><R><R><R><A><W><Q><A><S><R><E><S><K><L><Q><P><L><P><S><C><E><V><C><A><T><P><S><P><E><E><V><Q><S><W><A><Q><S><F><D><K><L><M><H><S><P><A><G><R><S><V><F><R><A><F... | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of t... | P49795 |
Q9ULC0 | MUCEN_HUMAN | Mucin-14 | Homo | <M><E><L><L><Q><V><T><I><L><F><L><L><P><S><I><C><S><S><N><S><T><G><V><L><E><A><A><N><N><S><L><V><V><T><T><T><K><P><S><I><T><T><P><N><T><E><S><L><Q><K><N><V><V><T><P><T><T><G><T><T><P><K><G><T><I><T><N><E><L><L><K><M><S><L><M><S><T><A><T><F><L><T><S><K><D><E><G><L><K><A><T><T><T><D><V><R><K><N><D><S><I><I><S><N><V><T><V... | Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.<BOP> | Q9ULC0 |
Q14244 | MAP7_HUMAN | Microtubule-associated protein 7 | Homo | <M><A><E><L><G><A><G><G><D><G><H><R><G><G><D><G><A><V><R><S><E><T><A><P><D><S><Y><K><V><Q><D><K><K><N><A><S><S><R><P><A><S><A><I><S><G><Q><N><N><N><H><S><G><N><K><P><D><P><P><P><V><L><R><V><D><D><R><Q><R><L><A><R><E><R><R><E><E><R><E><K><Q><L><A><A><R><E><I><V><W><L><E><R><E><E><R><A><R><Q><H><Y><E><K><H><L><E><E><R><K... | Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redist... | Q14244 |
Q7Z7K0 | COXM1_HUMAN | COX assembly mitochondrial protein homolog | Homo | <M><A><L><D><P><A><D><Q><H><L><R><H><V><E><K><D><V><L><I><P><K><I><M><R><E><K><A><K><E><R><C><S><E><Q><V><Q><D><F><T><K><C><C><K><N><S><G><V><L><M><V><V><K><C><R><K><E><N><S><A><L><K><E><C><L><T><A><Y><Y><N><D><P><A><F><Y><E><E><C><K><M><E><Y><L><K><E><R><E><E><F><R><K><T><G><I><P><T><K><K><R><L><Q><K><L><P><T><S><M> | Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.<BOP> | Q7Z7K0 |
Q96HN2 | SAHH3_HUMAN | S-adenosylhomocysteine hydrolase-like protein 2 | Homo | <M><S><V><Q><V><V><S><A><A><A><A><A><K><V><P><E><V><E><L><K><D><L><S><P><S><E><A><E><S><Q><L><G><L><S><T><A><A><V><G><A><M><A><P><P><A><G><G><G><D><P><E><A><P><A><P><A><A><E><R><P><P><V><P><G><P><G><S><G><P><A><A><A><L><S><P><A><A><G><K><V><P><Q><A><S><A><M><K><R><S><D><P><H><H><Q><H><Q><R><H><R><D><G><G><E><A><L><V><S... | May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate .<BOP> | Q96HN2 |
P14210 | HGF_HUMAN | Hepatocyte growth factor beta chain | Homo | <M><W><V><T><K><L><L><P><A><L><L><L><Q><H><V><L><L><H><L><L><L><L><P><I><A><I><P><Y><A><E><G><Q><R><K><R><R><N><T><I><H><E><F><K><K><S><A><K><T><T><L><I><K><I><D><P><A><L><K><I><K><T><K><K><V><N><T><A><D><Q><C><A><N><R><C><T><R><N><K><G><L><P><F><T><C><K><A><F><V><F><D><K><A><R><K><Q><C><L><W><F><P><F><N><S><M><S><S><G... | Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.<BOP> | P14210 |
Q9NRY7 | PLS2_HUMAN | Ca(2+)-dependent phospholipid scramblase 2 | Homo | <M><R><S><W><N><S><L><F><C><L><N><S><S><R><P><P><G><H><I><V><Y><P><K><H><Q><A><G><H><T><G><K><Q><A><D><H><L><G><S><Q><A><F><Y><P><G><R><Q><H><D><Y><L><V><P><P><A><G><T><A><G><I><P><V><Q><N><Q><P><G><R><P><E><G><V><P><W><M><P><A><P><P><P><P><L><N><C><P><P><G><L><E><Y><L><S><Q><I><D><M><I><L><I><H><Q><Q><I><E><L><L><E><V... | Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.<BOP> | Q9NRY7 |
P0DP06 | HVD34_HUMAN | Immunoglobulin heavy variable 4-30-4 | Homo | <M><K><H><L><W><F><F><L><L><L><V><A><A><P><R><W><V><L><S><Q><V><Q><L><Q><E><S><G><P><G><L><V><K><P><S><Q><T><L><S><L><T><C><T><V><S><G><G><S><I><S><S><G><D><Y><Y><W><S><W><I><R><Q><P><P><G><K><G><L><E><W><I><G><Y><I><Y><Y><S><G><S><T><Y><Y><N><P><S><L><K><S><R><V><T><I><S><V><D><T><S><K><N><Q><F><S><L><K><L><S><S><V><T... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P0DP06 |
Q6ZVZ8 | ASB18_HUMAN | Ankyrin repeat and SOCS box protein 18 | Homo | <M><S><N><S><D><Y><L><P><D><Y><P><L><N><S><D><L><V><K><R><L><K><S><A><L><D><A><K><D><E><E><R><V><R><D><L><I><C><T><E><I><T><P><V><D><A><V><I><E><L><A><N><D><D><W><M><K><D><P><S><A><Q><L><P><T><G><M><L><L><G><D><L><D><H><L><K><P><L><M><D><Q><F><F><Q><D><A><N><V><V><F><E><I><N><K><D><E><M><E><W><Q><V><K><S><P><A><T><F><G... | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q6ZVZ8 |
Q5JT25 | RAB41_HUMAN | Ras-related protein Rab-41 | Homo | <M><S><A><F><G><H><D><E><A><W><M><E><A><G><G><F><G><L><E><A><A><E><R><T><E><Y><Q><S><L><C><K><S><K><L><L><F><L><G><E><Q><S><V><G><K><T><S><I><I><S><R><F><M><Y><N><S><F><G><C><A><C><Q><A><T><V><G><I><D><F><L><S><K><T><M><Y><L><E><D><Q><I><V><Q><L><Q><L><W><D><T><A><G><Q><E><R><F><H><S><L><I><P><S><Y><I><R><D><S><T><I><A... | Required for normal Golgi ribbon organization and ER-to-Golgi trafficking.<BOP> | Q5JT25 |
Q9Y2V0 | CDIN1_HUMAN | Protein HH114 | Homo | <M><I><L><T><K><A><Q><Y><D><E><I><A><Q><C><L><V><S><V><P><P><T><R><Q><S><L><R><K><L><K><Q><R><F><P><S><Q><S><Q><A><T><L><L><S><I><F><S><Q><E><Y><Q><K><H><I><K><R><T><H><A><K><H><H><T><S><E><A><I><E><S><Y><Y><Q><R><Y><L><N><G><V><V><K><N><G><A><A><P><V><L><L><D><L><A><N><E><V><D><Y><A><P><S><L><M><A><R><L><I><L><E><R><F... | Plays a role in erythroid cell differentiation.<BOP> | Q9Y2V0 |
Q9UHY1 | NRBP_HUMAN | Nuclear receptor-binding protein | Homo | <M><S><E><G><E><S><Q><T><V><L><S><S><G><S><D><P><K><V><E><S><S><S><S><A><P><G><L><T><S><V><S><P><P><V><T><S><T><T><S><A><A><S><P><E><E><E><E><E><S><E><D><E><S><E><I><L><E><E><S><P><C><G><R><W><Q><K><R><R><E><E><V><N><Q><R><N><V><P><G><I><D><S><A><Y><L><A><M><D><T><E><E><G><V><E><V><V><W><N><E><V><Q><F><S><E><R><K><N><Y... | May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral repli... | Q9UHY1 |
P15036 | ETS2_HUMAN | Protein C-ets-2 | Homo | <M><N><D><F><G><I><K><N><M><D><Q><V><A><P><V><A><N><S><Y><R><G><T><L><K><R><Q><P><A><F><D><T><F><D><G><S><L><F><A><V><F><P><S><L><N><E><E><Q><T><L><Q><E><V><P><T><G><L><D><S><I><S><H><D><S><A><N><C><E><L><P><L><L><T><P><C><S><K><A><V><M><S><Q><A><L><K><A><T><F><S><G><F><K><K><E><Q><R><R><L><G><I><P><K><N><P><W><L><W><S... | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.<BOP> | P15036 |
Q16655 | MAR1_HUMAN | Protein Melan-A | Homo | <M><P><R><E><D><A><H><F><I><Y><G><Y><P><K><K><G><H><G><H><S><Y><T><T><A><E><E><A><A><G><I><G><I><L><T><V><I><L><G><V><L><L><L><I><G><C><W><Y><C><R><R><R><N><G><Y><R><A><L><M><D><K><S><L><H><V><G><T><Q><C><A><L><T><R><R><C><P><Q><E><G><F><D><H><R><D><S><K><V><S><L><Q><E><K><N><C><E><P><V><V><P><N><A><P><P><A><Y><E><K><L... | Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.<BOP> | Q16655 |
Q13239 | SLAP1_HUMAN | Src-like-adapter protein 1 | Homo | <M><G><N><S><M><K><S><T><P><A><P><A><E><R><P><L><P><N><P><E><G><L><D><S><D><F><L><A><V><L><S><D><Y><P><S><P><D><I><S><P><P><I><F><R><R><G><E><K><L><R><V><I><S><D><E><G><G><W><W><K><A><I><S><L><S><T><G><R><E><S><Y><I><P><G><I><C><V><A><R><V><Y><H><G><W><L><F><E><G><L><G><R><D><K><A><E><E><L><L><Q><L><P><D><T><K><V><G><S... | Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading... | Q13239 |
Q16769 | QPCT_HUMAN | Glutamyl cyclase | Homo | <M><A><G><G><R><H><R><R><V><V><G><T><L><H><L><L><L><L><V><A><A><L><P><W><A><S><R><G><V><S><P><S><A><S><A><W><P><E><E><K><N><Y><H><Q><P><A><I><L><N><S><S><A><L><R><Q><I><A><E><G><T><S><I><S><E><M><W><Q><N><D><L><Q><P><L><L><I><E><R><Y><P><G><S><P><G><S><Y><A><A><R><Q><H><I><M><Q><R><I><Q><R><L><Q><A><D><W><V><L><E><I><D... | Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of ... | Q16769 |
P51668 | UB2D1_HUMAN | Ubiquitin-protein ligase D1 | Homo | <M><A><L><K><R><I><Q><K><E><L><S><D><L><Q><R><D><P><P><A><H><C><S><A><G><P><V><G><D><D><L><F><H><W><Q><A><T><I><M><G><P><P><D><S><A><Y><Q><G><G><V><F><F><L><T><V><H><F><P><T><D><Y><P><F><K><P><P><K><I><A><F><T><T><K><I><Y><H><P><N><I><N><S><N><G><S><I><C><L><D><I><L><R><S><Q><W><S><P><A><L><T><V><S><K><V><L><L><S><I><C... | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins . In vitro catalyzes 'Lys-48'-linked polyubiquitination . Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 a... | P51668 |
Q96LB8 | PGRP4_HUMAN | Peptidoglycan recognition protein intermediate beta | Homo | <M><L><P><W><L><L><V><F><S><A><L><G><I><Q><A><W><G><D><S><S><W><N><K><T><Q><A><K><Q><V><S><E><G><L><Q><Y><L><F><E><N><I><S><Q><L><T><E><K><G><L><P><T><D><V><S><T><T><V><S><R><K><A><W><G><A><E><A><V><G><C><S><I><Q><L><T><T><P><V><N><V><L><V><I><H><H><V><P><G><L><E><C><H><D><Q><T><V><C><S><Q><R><L><R><E><L><Q><A><H><H><V... | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bact... | Q96LB8 |
Q8N1E6 | FXL14_HUMAN | F-box and leucine-rich repeat protein 14 | Homo | <M><E><T><H><I><S><C><L><F><P><E><L><L><A><M><I><F><G><Y><L><D><V><R><D><K><G><R><A><A><Q><V><C><T><A><W><R><D><A><A><Y><H><K><S><V><W><R><G><V><E><A><K><L><H><L><R><R><A><N><P><S><L><F><P><S><L><Q><A><R><G><I><R><R><V><Q><I><L><S><L><R><R><S><L><S><Y><V><I><Q><G><M><A><N><I><E><S><L><N><L><S><G><C><Y><N><L><T><D><N><G... | Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.<BOP> | Q8N1E6 |
Q5VWZ2 | LYPL1_HUMAN | Lysophospholipase-like protein 1 | Homo | <M><A><A><A><S><G><S><V><L><Q><R><C><I><V><S><P><A><G><R><H><S><A><S><L><I><F><L><H><G><S><G><D><S><G><Q><G><L><R><M><W><I><K><Q><V><L><N><Q><D><L><T><F><Q><H><I><K><I><I><Y><P><T><A><P><P><R><S><Y><T><P><M><K><G><G><I><S><N><V><W><F><D><R><F><K><I><T><N><D><C><P><E><H><L><E><S><I><D><V><M><C><Q><V><L><T><D><L><I><D><E... | Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.<BOP> | Q5VWZ2 |
Q92185 | SIA8A_HUMAN | Sialyltransferase St8Sia I | Homo | <M><S><P><C><G><R><A><R><R><Q><T><S><R><G><A><M><A><V><L><A><W><K><F><P><R><T><R><L><P><M><G><A><S><A><L><C><V><V><V><L><C><W><L><Y><I><F><P><V><Y><R><L><P><N><E><K><E><I><V><Q><G><V><L><Q><Q><G><T><A><W><R><R><N><Q><T><A><A><R><A><F><R><K><Q><M><E><D><C><C><D><P><A><H><L><F><A><M><T><K><M><N><S><P><M><G><K><S><M><W><Y... | Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid . Can catalyze the addition of a second alpha-2,8-sialic acid to GD3 to form GT... | Q92185 |
O95436 | NPT2B_HUMAN | Solute carrier family 34 member 2 | Homo | <M><A><P><W><P><E><L><G><D><A><Q><P><N><P><D><K><Y><L><E><G><A><A><G><Q><Q><P><T><A><P><D><K><S><K><E><T><N><K><T><D><N><T><E><A><P><V><T><K><I><E><L><L><P><S><Y><S><T><A><T><L><I><D><E><P><T><E><V><D><D><P><W><N><L><P><T><L><Q><D><S><G><I><K><W><S><E><R><D><T><K><G><K><I><L><C><F><F><Q><G><I><G><R><L><I><L><L><L><G><F... | Involved in actively transporting phosphate into cells via Na(+) cotransport.<BOP> | O95436 |
Q8NGT2 | O13J1_HUMAN | Olfactory receptor OR9-2 | Homo | <M><E><P><L><N><R><T><E><V><S><E><F><F><L><K><G><F><S><G><Y><P><A><L><E><H><L><L><F><P><L><C><S><A><M><Y><L><V><T><L><L><G><N><T><A><I><M><A><V><S><V><L><D><I><H><L><H><T><P><V><Y><F><F><L><G><N><L><S><T><L><D><I><C><Y><T><P><T><F><V><P><L><M><L><V><H><L><L><S><S><R><K><T><I><S><F><A><V><C><A><I><Q><M><C><L><S><L><S><T... | Odorant receptor.<BOP> | Q8NGT2 |
Q9UMR3 | TBX20_HUMAN | T-box transcription factor TBX20 | Homo | <M><E><F><T><A><S><P><K><P><Q><L><S><S><R><A><N><A><F><S><I><A><A><L><M><S><S><G><G><S><K><E><K><E><A><T><E><N><T><I><K><P><L><E><Q><F><V><E><K><S><S><C><A><Q><P><L><G><E><L><T><S><L><D><A><H><G><E><F><G><G><G><S><G><S><S><P><S><S><S><S><L><C><T><E><P><L><I><P><T><T><P><I><I><P><S><E><E><M><A><K><I><A><C><S><L><E><T><K... | Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart.<BOP> | Q9UMR3 |
O95718 | ERR2_HUMAN | Nuclear receptor subfamily 3 group B member 2 | Homo | <M><S><S><D><D><R><H><L><G><S><S><C><G><S><F><I><K><T><E><P><S><S><P><S><S><G><I><D><A><L><S><H><H><S><P><S><G><S><S><D><A><S><G><G><F><G><L><A><L><G><T><H><A><N><G><L><D><S><P><P><M><F><A><G><A><G><L><G><G><T><P><C><R><K><S><Y><E><D><C><A><S><G><I><M><E><D><S><A><I><K><C><E><Y><M><L><N><A><I><P><K><R><L><C><L><V><C><G... | Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity. Positively regulates ESR1 transcriptional activity upon E2 stimulation.<BOP> | O95718 |
A0A0C4DH72 | KV106_HUMAN | Immunoglobulin kappa variable 1-6 | Homo | <M><D><M><R><V><P><A><Q><L><L><G><L><L><L><L><W><L><P><G><A><R><C><A><I><Q><M><T><Q><S><P><S><S><L><S><A><S><V><G><D><R><V><T><I><T><C><R><A><S><Q><G><I><R><N><D><L><G><W><Y><Q><Q><K><P><G><K><A><P><K><L><L><I><Y><A><A><S><S><L><Q><S><G><V><P><S><R><F><S><G><S><G><S><G><T><D><F><T><L><T><I><S><S><L><Q><P><E><D><F><A><T... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0C4DH72 |
Q06547 | GABP1_HUMAN | Transcription factor E4TF1-53 | Homo | <M><S><L><V><D><L><G><K><K><L><L><E><A><A><R><A><G><Q><D><D><E><V><R><I><L><M><A><N><G><A><P><F><T><T><D><W><L><G><T><S><P><L><H><L><A><A><Q><Y><G><H><Y><S><T><T><E><V><L><L><R><A><G><V><S><R><D><A><R><T><K><V><D><R><T><P><L><H><M><A><A><S><E><G><H><A><S><I><V><E><V><L><L><K><H><G><A><D><V><N><A><K><D><M><L><K><M><T><A... | (Microbial infection) Necessary for the expression of the Adenovirus E4 gene.<BOP> | Q06547 |
Q9UHR6 | ZNHI2_HUMAN | Protein FON | Homo | <M><E><P><A><G><P><C><G><F><C><P><A><G><E><V><Q><P><A><R><Y><T><C><P><R><C><N><A><P><Y><C><S><L><R><C><Y><R><T><H><G><T><C><A><E><N><F><Y><R><D><Q><V><L><G><E><L><R><G><C><S><A><P><P><S><R><L><A><S><A><L><R><R><L><R><Q><Q><R><E><T><E><D><E><P><G><E><A><G><L><S><S><G><P><A><P><G><G><L><S><G><L><W><E><R><L><A><P><G><E><K... | May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) . Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 . May play a role in regulatin... | Q9UHR6 |
Q14119 | VEZF1_HUMAN | Zinc finger protein 161 | Homo | <M><E><A><N><W><T><A><F><L><F><Q><A><H><E><A><S><H><H><Q><Q><Q><A><A><Q><N><S><L><L><P><L><L><S><S><A><V><E><P><P><D><Q><K><P><L><L><P><I><P><I><T><Q><K><P><Q><G><A><P><E><T><L><K><D><A><I><G><I><K><K><E><K><P><K><T><S><F><V><C><T><Y><C><S><K><A><F><R><D><S><Y><H><L><R><R><H><E><S><C><H><T><G><I><K><L><V><S><R><P><K><K... | Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.<BOP> | Q14119 |
Q96NI6 | LRFN5_HUMAN | Leucine-rich repeat and fibronectin type-III domain-containing protein 5 | Homo | <M><E><K><I><L><F><Y><L><F><L><I><G><I><A><V><K><A><Q><I><C><P><K><R><C><V><C><Q><I><L><S><P><N><L><A><T><L><C><A><K><K><G><L><L><F><V><P><P><N><I><D><R><R><T><V><E><L><R><L><A><D><N><F><V><T><N><I><K><R><K><D><F><A><N><M><T><S><L><V><D><L><T><L><S><R><N><T><I><S><F><I><T><P><H><A><F><A><D><L><R><N><L><R><A><L><H><L><N... | Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons.<BOP> | Q96NI6 |
Q0WX57 | U17LO_HUMAN | Ubiquitin-specific-processing protease 17 | Homo | <M><E><D><D><S><L><Y><L><R><G><E><W><Q><F><N><H><F><S><K><L><T><S><S><R><P><D><A><A><F><A><E><I><Q><R><T><S><L><P><E><K><S><P><L><S><C><E><T><R><V><D><L><C><D><D><L><A><P><V><A><R><Q><L><A><P><R><E><K><L><P><L><S><S><R><R><P><A><A><V><G><A><G><L><Q><N><M><G><N><T><C><Y><V><N><A><S><L><Q><C><L><T><Y><T><P><P><L><A><N><Y... | Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.<BOP> | Q0WX57 |
Q9NPH5 | NOX4_HUMAN | Renal NAD(P)H-oxidase | Homo | <M><A><V><S><W><R><S><W><L><A><N><E><G><V><K><H><L><C><L><F><I><W><L><S><M><N><V><L><L><F><W><K><T><F><L><L><Y><N><Q><G><P><E><Y><H><Y><L><H><Q><M><L><G><L><G><L><C><L><S><R><A><S><A><S><V><L><N><L><N><C><S><L><I><L><L><P><M><C><R><T><L><L><A><Y><L><R><G><S><Q><K><V><P><S><R><R><T><R><R><L><L><D><K><S><R><T><F><H><I><T... | Involved in redox signaling in vascular cells. Constitutively and NADPH-dependently generates reactive oxygen species (ROS). Modulates the nuclear activation of ERK1/2 and the ELK1 transcription factor, and is capable of inducing nuclear DNA damage. Displays an increased activity relative to isoform 1.<BOP> | Q9NPH5 |
Q8N1D5 | CF107_HUMAN | Cilia- and flagella-associated protein 107 | Homo | <M><F><L><T><A><V><N><P><Q><P><L><S><T><P><S><W><Q><I><E><T><K><Y><S><T><K><V><L><T><G><N><W><M><E><E><R><R><K><F><T><R><D><T><D><K><T><P><Q><S><I><Y><R><K><E><Y><I><P><F><P><D><H><R><P><D><Q><I><S><R><W><Y><G><K><R><K><V><E><G><L><P><Y><K><H><L><I><T><H><H><Q><E><P><P><H><R><Y><L><I><S><T><Y><D><D><H><Y><N><R><H><G><Y... | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.<BOP> | Q8N1D5 |
Q7L592 | NDUF7_HUMAN | Protein midA homolog | Homo | <M><S><V><L><L><R><S><G><L><G><P><L><C><A><V><A><R><A><A><I><P><F><I><W><R><G><K><Y><F><S><S><G><N><E><P><A><E><N><P><V><T><P><M><L><R><H><L><M><Y><K><I><K><S><T><G><P><I><T><V><A><E><Y><M><K><E><V><L><T><N><P><A><K><G><Y><Y><V><Y><R><D><M><L><G><E><K><G><D><F><I><T><S><P><E><I><S><Q><I><F><G><E><L><L><G><I><W><F><I><S... | Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) . Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex .<BOP> | Q7L592 |
O60784 | TOM1_HUMAN | Target of Myb protein 1 | Homo | <M><D><F><L><L><G><N><P><F><S><S><P><V><G><Q><R><I><E><K><A><T><D><G><S><L><Q><S><E><D><W><A><L><N><M><E><I><C><D><I><I><N><E><T><E><E><G><P><K><D><A><L><R><A><V><K><K><R><I><V><G><N><K><N><F><H><E><V><M><L><A><L><T><V><L><E><T><C><V><K><N><C><G><H><R><F><H><V><L><V><A><S><Q><D><F><V><E><S><V><L><V><R><T><I><L><P><K><N... | Adapter protein that plays a role in the intracellular membrane trafficking of ubiquitinated proteins, thereby participating in autophagy, ubiquitination-dependent signaling and receptor recycling pathways . Acts as a MYO6/Myosin VI adapter protein that targets MYO6 to endocytic structures . Together with MYO6, require... | O60784 |
Q96RP3 | UCN2_HUMAN | Urocortin-related peptide | Homo | <M><T><R><C><A><L><L><L><L><M><V><L><M><L><G><R><V><L><V><V><P><V><T><P><I><P><T><F><Q><L><R><P><Q><N><S><P><Q><T><T><P><R><P><A><A><S><E><S><P><S><A><A><P><T><W><P><W><A><A><Q><S><H><C><S><P><T><R><H><P><G><S><R><I><V><L><S><L><D><V><P><I><G><L><L><Q><I><L><L><E><Q><A><R><A><R><A><A><R><E><Q><A><T><T><N><A><R><I><L><A... | Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.<BOP> | Q96RP3 |
O95998 | I18BP_HUMAN | Tadekinig-alfa | Homo | <M><T><M><R><H><N><W><T><P><D><L><S><P><L><W><V><L><L><L><C><A><H><V><V><T><L><L><V><R><A><T><P><V><S><Q><T><T><T><A><A><T><A><S><V><R><S><T><K><D><P><C><P><S><Q><P><P><V><F><P><A><A><K><Q><C><P><A><L><E><V><T><W><P><E><V><E><V><P><L><N><G><T><L><S><L><S><C><V><A><C><S><R><F><P><N><F><S><I><L><Y><W><L><G><N><G><S><F><I... | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.<BOP> | O95998 |
Q15131 | CDK10_HUMAN | Serine/threonine-protein kinase PISSLRE | Homo | <M><A><E><P><D><L><E><C><E><Q><I><R><L><K><C><I><R><K><E><G><F><F><T><V><P><P><E><H><R><L><G><R><C><R><S><V><K><E><F><E><K><L><N><R><I><G><E><G><T><Y><G><I><V><Y><R><A><R><D><T><Q><T><D><E><I><V><A><L><K><K><V><R><M><D><K><E><K><D><G><I><P><I><S><S><L><R><E><I><T><L><L><L><R><L><R><H><P><N><I><V><E><L><K><E><V><V><V><G... | Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) . Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenes... | Q15131 |
Q9BUR4 | TCAB1_HUMAN | WD40 repeat-containing protein antisense to TP53 gene | Homo | <M><K><T><L><E><T><Q><P><L><A><P><D><C><C><P><S><D><Q><D><P><A><P><A><H><P><S><P><H><A><S><P><M><N><K><N><A><D><S><E><L><M><P><P><P><P><E><R><G><D><P><P><R><L><S><P><D><P><V><A><G><S><A><V><S><Q><E><L><R><E><G><D><P><V><S><L><S><T><P><L><E><T><E><F><G><S><P><S><E><L><S><P><R><I><E><E><Q><E><L><S><E><N><T><S><L><P><A><E... | RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies . Specifically recognizes and binds the Cajal body box (CAB box) present in both small Cajal body RNAs (scaRNAs) and telomerase RNA template component (TERC) . Essential component of the telomerase holoenzyme complex, a rib... | Q9BUR4 |
P11908 | PRPS2_HUMAN | Phosphoribosyl pyrophosphate synthase II | Homo | <M><P><N><I><V><L><F><S><G><S><S><H><Q><D><L><S><Q><R><V><A><D><R><L><G><L><E><L><G><K><V><V><T><K><K><F><S><N><Q><E><T><S><V><E><I><G><E><S><V><R><G><E><D><V><Y><I><I><Q><S><G><C><G><E><I><N><D><N><L><M><E><L><L><I><M><I><N><A><C><K><I><A><S><S><S><R><V><T><A><V><I><P><C><F><P><Y><A><R><Q><D><K><K><D><K><S><R><A><P><I... | Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.<BOP> | P11908 |
Q9NVQ4 | FAIM1_HUMAN | Fas apoptotic inhibitory molecule 1 | Homo | <M><T><D><L><V><A><V><W><D><V><A><L><S><D><G><V><H><K><I><E><F><E><H><G><T><T><S><G><K><R><V><V><Y><V><D><G><K><E><E><I><R><K><E><W><M><F><K><L><V><G><K><E><T><F><Y><V><G><A><A><K><T><K><A><T><I><N><I><D><A><I><S><G><F><A><Y><E><Y><T><L><E><I><N><G><K><S><L><K><K><Y><M><E><D><R><S><K><T><T><N><T><W><V><L><H><M><D><G><E... | Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.<BOP> | Q9NVQ4 |
Q96CG8 | CTHR1_HUMAN | Collagen triple helix repeat-containing protein 1 | Homo | <M><R><P><Q><G><P><A><A><S><P><Q><R><L><R><G><L><L><L><L><L><L><L><Q><L><P><A><P><S><S><A><S><E><I><P><K><G><K><Q><K><A><Q><L><R><Q><R><E><V><V><D><L><Y><N><G><M><C><L><Q><G><P><A><G><V><P><G><R><D><G><S><P><G><A><N><G><I><P><G><T><P><G><I><P><G><R><D><G><F><K><G><E><K><G><E><C><L><R><E><S><F><E><E><S><W><T><P><N><Y><K... | May act as a negative regulator of collagen matrix deposition.<BOP> | Q96CG8 |
Q14201 | BTG3_HUMAN | Protein Tob5 | Homo | <M><K><N><E><I><A><A><V><V><F><F><F><T><R><L><V><R><K><H><D><K><L><K><K><E><A><V><E><R><F><A><E><K><L><T><L><I><L><Q><E><K><Y><K><N><H><W><Y><P><E><K><P><S><K><G><Q><A><Y><R><C><I><R><V><N><K><F><Q><R><V><D><P><D><V><L><K><A><C><E><N><S><C><I><L><Y><S><D><L><G><L><P><K><E><L><T><L><W><V><D><P><C><E><V><C><C><R><Y><G><E... | Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.<BOP> | Q14201 |
Q86W42 | THOC6_HUMAN | WD repeat-containing protein 58 | Homo | <M><E><R><A><V><P><L><A><V><P><L><G><Q><T><E><V><F><Q><A><L><Q><R><L><H><M><T><I><F><S><Q><S><V><S><P><C><G><K><F><L><A><A><G><N><N><Y><G><Q><I><A><I><F><S><L><S><S><A><L><S><S><E><A><K><E><E><S><K><K><P><V><V><T><F><Q><A><H><D><G><P><V><Y><S><M><V><S><T><D><R><H><L><L><S><A><G><D><G><E><V><K><A><W><L><W><A><E><M><L><K... | Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstre... | Q86W42 |
O95006 | OR2F2_HUMAN | Olfactory receptor OR7-6 | Homo | <M><E><I><D><N><Q><T><W><V><R><E><F><I><L><L><G><L><S><S><D><W><C><T><Q><I><S><L><F><S><L><F><L><V><T><Y><L><M><T><V><L><G><N><C><L><I><V><L><L><I><R><L><D><S><R><L><H><T><P><M><Y><F><F><L><T><N><L><S><L><V><D><V><S><Y><A><T><S><V><V><P><Q><L><L><A><H><F><L><A><E><H><K><A><I><P><F><Q><S><C><A><A><Q><L><F><F><S><L><A><L... | Odorant receptor.<BOP> | O95006 |
P43351 | RAD52_HUMAN | DNA repair protein RAD52 homolog | Homo | <M><S><G><T><E><E><A><I><L><G><G><R><D><S><H><P><A><A><G><G><G><S><V><L><C><F><G><Q><C><Q><Y><T><A><E><E><Y><Q><A><I><Q><K><A><L><R><Q><R><L><G><P><E><Y><I><S><S><R><M><A><G><G><G><Q><K><V><C><Y><I><E><G><H><R><V><I><N><L><A><N><E><M><F><G><Y><N><G><W><A><H><S><I><T><Q><Q><N><V><D><F><V><D><L><N><N><G><K><F><Y><V><G><V... | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.<BOP> | P43351 |
Q8IV38 | ANKY2_HUMAN | Ankyrin repeat and MYND domain-containing protein 2 | Homo | <M><V><H><I><K><K><G><E><L><T><Q><E><E><K><E><L><L><E><V><I><G><K><G><T><V><Q><E><A><G><T><L><L><S><S><K><N><V><R><V><N><C><L><D><E><N><G><M><T><P><L><M><H><A><A><Y><K><G><K><L><D><M><C><K><L><L><L><R><H><G><A><D><V><N><C><H><Q><H><E><H><G><Y><T><A><L><M><F><A><A><L><S><G><N><K><D><I><T><W><V><M><L><E><A><G><A><E><T><D... | May be involved in the trafficking of signaling proteins to the cilia.<BOP> | Q8IV38 |
P0C646 | O52Z1_HUMAN | Olfactory receptor 52Z1P | Homo | <M><G><I><P><G><L><E><G><L><H><T><W><I><S><I><P><F><S><F><M><Y><I><V><A><V><A><G><N><I><F><L><I><F><L><I><M><T><E><R><S><L><H><E><P><M><Y><L><F><L><S><M><L><A><S><A><D><F><L><L><A><T><A><A><A><P><K><V><L><A><I><L><W><F><H><S><M><D><I><S><F><G><S><C><V><S><Q><M><F><F><I><H><F><I><F><V><A><E><S><A><I><L><L><A><M><A><F><D... | Odorant receptor.<BOP> | P0C646 |
Q86T03 | PP4P1_HUMAN | Transmembrane protein 55B | Homo | <M><A><A><D><G><E><R><S><P><L><L><S><E><P><I><D><G><G><A><G><G><N><G><L><V><G><P><G><G><S><G><A><G><P><G><G><G><L><T><P><S><A><P><P><Y><G><A><A><F><P><P><F><P><E><G><H><P><A><V><L><P><G><E><D><P><P><P><Y><S><P><L><T><S><P><D><S><G><S><A><P><M><I><T><C><R><V><C><Q><S><L><I><N><V><E><G><K><M><H><Q><H><V><V><K><C><G><V><C... | Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P) . Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosph... | Q86T03 |
Q8N4B4 | FBX39_HUMAN | F-box only protein 39 | Homo | <M><D><E><E><S><E><L><I><Q><P><Q><D><Q><S><C><W><A><F><L><P><D><L><C><L><C><R><V><F><W><W><L><G><D><R><D><R><S><R><A><A><L><V><C><R><K><W><N><Q><M><M><Y><S><A><E><L><W><R><Y><R><T><I><T><F><S><G><R><P><S><R><V><H><A><S><E><V><E><S><A><V><W><Y><V><K><K><F><G><R><Y><L><E><H><L><E><V><K><F><M><N><P><Y><N><A><V><L><T><K><K... | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<BOP> | Q8N4B4 |
Q9Y5X4 | NR2E3_HUMAN | Retina-specific nuclear receptor | Homo | <M><E><T><R><P><T><A><L><M><S><S><T><V><A><A><A><A><P><A><A><G><A><A><S><R><K><E><S><P><G><R><W><G><L><G><E><D><P><T><G><V><S><P><S><L><Q><C><R><V><C><G><D><S><S><S><G><K><H><Y><G><I><Y><A><C><N><G><C><S><G><F><F><K><R><S><V><R><R><R><L><I><Y><R><C><Q><V><G><A><G><M><C><P><V><D><K><A><H><R><N><Q><C><Q><A><C><R><L><K><K... | Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances r... | Q9Y5X4 |
P63120 | VPK19_HUMAN | Proteinase | Homo | <W><A><S><Q><V><S><E><N><R><P><V><C><K><A><I><I><Q><G><K><Q><F><E><G><L><V><D><T><G><A><D><V><S><I><I><A><L><N><Q><W><P><K><N><W><P><K><Q><K><A><V><T><G><L><V><G><I><G><T><A><S><E><V><Y><Q><S><T><E><I><L><H><C><L><G><P><D><N><Q><E><S><T><V><Q><P><M><I><T><S><I><P><L><N><L><W><G><R><D><L><L><Q><Q><W><G><A><E><I><T><M><P... | Retroviral proteases have roles in the processing of the primary translation products and the maturation of the viral particle. Endogenous Pro proteins may have kept, lost or modified their original function during evolution.<BOP> | P63120 |
Q8NGN8 | OR4A4_HUMAN | Olfactory receptor OR11-107 | Homo | <M><E><P><R><K><N><V><T><D><F><V><L><L><G><F><T><Q><N><P><K><E><Q><K><V><L><F><V><M><F><L><L><F><Y><I><L><T><M><V><G><N><L><L><I><V><V><T><V><T><V><S><E><T><L><G><S><P><M><S><F><F><L><A><G><L><T><F><I><D><I><I><Y><S><S><S><I><S><P><R><L><I><S><D><L><F><F><G><N><N><S><I><S><F><Q><S><F><M><A><Q><L><F><I><E><H><L><F><G><G... | Odorant receptor.<BOP> | Q8NGN8 |
Q8N511 | TM199_HUMAN | Transmembrane protein 199 | Homo | <M><A><S><S><L><L><A><G><E><R><L><V><R><A><L><G><P><G><G><E><L><E><P><E><R><L><P><R><K><L><R><A><E><L><E><A><A><L><G><K><K><H><K><G><G><D><S><S><S><G><P><Q><R><L><V><S><F><R><L><I><R><D><L><H><Q><H><L><R><E><R><D><S><K><L><Y><L><H><E><L><L><E><G><S><E><I><Y><L><P><E><V><V><K><P><P><R><N><P><E><L><V><A><R><L><E><K><I><K... | Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent prote... | Q8N511 |
Q8N3R3 | TCAIM_HUMAN | Tolerance associated gene-1 protein | Homo | <M><F><C><H><L><R><P><M><R><R><L><C><L><E><K><I><F><P><H><W><F><P><F><S><R><A><L><S><G><A><E><A><V><N><A><L><R><P><F><Y><F><A><V><H><P><D><F><F><G><Q><H><P><V><E><R><E><I><N><E><N><S><L><K><R><L><S><V><Y><L><E><N><L><Q><K><P><G><F><K><S><L><K><P><T><Q><L><T><F><Y><V><R><E><T><D><Q><S><S><S><D><G><Q><E><P><F><S><T><S><G... | May regulate T-cell apoptosis.<BOP> | Q8N3R3 |
Q9BRR3 | PGAP4_HUMAN | Transmembrane protein 246 | Homo | <M><S><T><S><T><S><P><A><A><M><L><L><R><R><L><R><R><L><S><W><G><S><T><A><V><Q><L><F><I><L><T><V><V><T><F><G><L><L><A><P><L><A><C><H><R><L><L><H><S><Y><F><Y><L><R><H><W><H><L><N><Q><M><S><Q><E><F><L><Q><Q><S><L><K><E><G><E><A><A><L><H><Y><F><E><E><L><P><S><A><N><G><S><V><P><I><V><W><Q><A><T><P><R><P><W><L><V><I><T><I><I... | Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins . Required for the initial step of GPI-GalNAc bio... | Q9BRR3 |
Q9UBC9 | SPRR3_HUMAN | Esophagin | Homo | <M><S><S><Y><Q><Q><K><Q><T><F><T><P><P><P><Q><L><Q><Q><Q><Q><V><K><Q><P><S><Q><P><P><P><Q><E><I><F><V><P><T><T><K><E><P><C><H><S><K><V><P><Q><P><G><N><T><K><I><P><E><P><G><C><T><K><V><P><E><P><G><C><T><K><V><P><E><P><G><C><T><K><V><P><E><P><G><C><T><K><V><P><E><P><G><C><T><K><V><P><E><P><G><C><T><K><V><P><E><P><G><Y><T... | Cross-linked envelope protein of keratinocytes.<BOP> | Q9UBC9 |
P43007 | SATT_HUMAN | Solute carrier family 1 member 4 | Homo | <M><E><K><S><N><E><T><N><G><Y><L><D><S><A><Q><A><G><P><A><A><G><P><G><A><P><G><T><A><A><G><R><A><R><R><C><A><G><F><L><R><R><Q><A><L><V><L><L><T><V><S><G><V><L><A><G><A><G><L><G><A><A><L><R><G><L><S><L><S><R><T><Q><V><T><Y><L><A><F><P><G><E><M><L><L><R><M><L><R><M><I><I><L><P><L><V><V><C><S><L><V><S><G><A><A><S><L><D><A... | Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.<BOP> | P43007 |
Q14627 | I13R2_HUMAN | Interleukin-13-binding protein | Homo | <M><A><F><V><C><L><A><I><G><C><L><Y><T><F><L><I><S><T><T><F><G><C><T><S><S><S><D><T><E><I><K><V><N><P><P><Q><D><F><E><I><V><D><P><G><Y><L><G><Y><L><Y><L><Q><W><Q><P><P><L><S><L><D><H><F><K><E><C><T><V><E><Y><E><L><K><Y><R><N><I><G><S><E><T><W><K><T><I><I><T><K><N><L><H><Y><K><D><G><F><D><L><N><K><G><I><E><A><K><I><H><T... | Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).<BOP> | Q14627 |
P02753 | RET4_HUMAN | Plasma retinol-binding protein(1-176) | Homo | <M><K><W><V><W><A><L><L><L><L><A><A><L><G><S><G><R><A><E><R><D><C><R><V><S><S><F><R><V><K><E><N><F><D><K><A><R><F><S><G><T><W><Y><A><M><A><K><K><D><P><E><G><L><F><L><Q><D><N><I><V><A><E><F><S><V><D><E><T><G><Q><M><S><A><T><A><K><G><R><V><R><L><L><N><N><W><D><V><C><A><D><M><V><G><T><F><T><D><T><E><D><P><A><K><F><K><M><K... | Retinol-binding protein that mediates retinol transport in blood plasma . Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane .<BOP> | P02753 |
P58294 | PROK1_HUMAN | Mambakine | Homo | <M><R><G><A><T><R><V><S><I><M><L><L><L><V><T><V><S><D><C><A><V><I><T><G><A><C><E><R><D><V><Q><C><G><A><G><T><C><C><A><I><S><L><W><L><R><G><L><R><M><C><T><P><L><G><R><E><G><E><E><C><H><P><G><S><H><K><V><P><F><F><R><K><R><K><H><H><T><C><P><C><L><P><N><L><L><C><S><R><F><P><D><G><R><Y><R><C><S><M><D><L><K><N><I><N><F> | Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferat... | P58294 |
P62945 | RL41_HUMAN | Large ribosomal subunit protein eL41 | Homo | <M><R><A><K><W><R><K><K><R><M><R><R><L><K><R><K><R><R><K><M><R><Q><R><S><K> | Interacts with the beta subunit of protein kinase CKII and stimulates phosphorylation of DNA topoisomerase II alpha by CKII.<BOP> | P62945 |
O95460 | MATN4_HUMAN | Matrilin-4 | Homo | <M><R><G><L><L><C><W><P><V><L><L><L><L><L><Q><P><W><E><T><Q><L><Q><L><T><G><P><R><C><H><T><G><P><L><D><L><V><F><V><I><D><S><S><R><S><V><R><P><F><E><F><E><T><M><R><Q><F><L><M><G><L><L><R><G><L><N><V><G><P><N><A><T><R><V><G><V><I><Q><Y><S><S><Q><V><Q><S><V><F><P><L><R><A><F><S><R><R><E><D><M><E><R><A><I><R><D><L><V><P><L... | Major component of the extracellular matrix of cartilage.<BOP> | O95460 |
Q9Y5N6 | ORC6_HUMAN | Origin recognition complex subunit 6 | Homo | <M><G><S><E><L><I><G><R><L><A><P><R><L><G><L><A><E><P><D><M><L><R><K><A><E><E><Y><L><R><L><S><R><V><K><C><V><G><L><S><A><R><T><T><E><T><S><S><A><V><M><C><L><D><L><A><A><S><W><M><K><C><P><L><D><R><A><Y><L><I><K><L><S><G><L><N><K><E><T><Y><Q><S><C><L><K><S><F><E><C><L><L><G><L><N><S><N><I><G><I><R><D><L><A><V><Q><F><S><C... | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind hist... | Q9Y5N6 |
Q8IWF6 | DEN6A_HUMAN | DENN domain-containing protein 6A | Homo | <M><A><L><R><G><P><A><G><L><G><P><G><S><R><R><P><L><D><E><A><V><A><G><A><E><G><R><E><A><P><A><L><V><A><A><G><G><A><P><E><D><D><E><E><D><D><G><R><G><R><G><L><L><R><W><D><S><F><S><A><W><L><H><C><V><C><V><V><G><F><D><L><E><L><G><Q><A><V><E><V><I><Y><P><Q><H><S><K><L><T><D><R><E><K><T><N><I><C><Y><L><S><F><P><D><S><N><S><G... | Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes.<BOP> | Q8IWF6 |
Q96HR8 | NAF1_HUMAN | H/ACA ribonucleoprotein complex non-core subunit NAF1 | Homo | <M><E><V><V><E><A><A><A><A><Q><L><E><T><L><K><F><N><G><T><D><F><G><V><G><E><G><P><A><A><P><S><P><G><S><A><P><V><P><G><T><Q><P><P><L><Q><S><F><E><G><S><P><D><A><G><Q><T><V><E><V><K><P><A><G><E><Q><P><L><Q><P><V><L><N><A><V><A><A><G><T><P><A><P><Q><P><Q><P><P><A><E><S><P><A><C><G><D><C><V><T><S><P><G><A><A><E><P><A><R><A... | RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with N... | Q96HR8 |
Q9Y6M5 | ZNT1_HUMAN | Solute carrier family 30 member 1 | Homo | <M><G><C><W><G><R><N><R><G><R><L><L><C><M><L><A><L><T><F><M><F><M><V><L><E><V><V><V><S><R><V><T><S><S><L><A><M><L><S><D><S><F><H><M><L><S><D><V><L><A><L><V><V><A><L><V><A><E><R><F><A><R><R><T><H><A><T><Q><K><N><T><F><G><W><I><R><A><E><V><M><G><A><L><V><N><A><I><F><L><T><G><L><C><F><A><I><L><L><E><A><I><E><R><F><I><E><P... | May be involved in zinc transport out of the cell.<BOP> | Q9Y6M5 |
Q9BWS9 | CHID1_HUMAN | Stabilin-1-interacting chitinase-like protein | Homo | <M><R><T><L><F><N><L><L><W><L><A><L><A><C><S><P><V><H><T><T><L><S><K><S><D><A><K><K><A><A><S><K><T><L><L><E><K><S><Q><F><S><D><K><P><V><Q><D><R><G><L><V><V><T><D><L><K><A><E><S><V><V><L><E><H><R><S><Y><C><S><A><K><A><R><D><R><H><F><A><G><D><V><L><G><Y><V><T><P><W><N><S><H><G><Y><D><V><T><K><V><F><G><S><K><F><T><Q><I><S... | Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro).<BOP> | Q9BWS9 |
Q04941 | PLP2_HUMAN | Intestinal membrane A4 protein | Homo | <M><A><D><S><E><R><L><S><A><P><G><C><W><A><A><C><T><N><F><S><R><T><R><K><G><I><L><L><F><A><E><I><I><L><C><L><V><I><L><I><C><F><S><A><S><T><P><G><Y><S><S><L><S><V><I><E><M><I><L><A><A><I><F><F><V><V><Y><M><C><D><L><H><T><K><I><P><F><I><N><W><P><W><S><D><F><F><R><T><L><I><A><A><I><L><Y><L><I><T><S><I><V><V><L><V><E><R><G... | May play a role in cell differentiation in the intestinal epithelium.<BOP> | Q04941 |
P51659 | DHB4_HUMAN | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase | Homo | <M><G><S><P><L><R><F><D><G><R><V><V><L><V><T><G><A><G><A><G><L><G><R><A><Y><A><L><A><F><A><E><R><G><A><L><V><V><V><N><D><L><G><G><D><F><K><G><V><G><K><G><S><L><A><A><D><K><V><V><E><E><I><R><R><R><G><G><K><A><V><A><N><Y><D><S><V><E><E><G><E><K><V><V><K><T><A><L><D><A><F><G><R><I><D><V><V><V><N><N><A><G><I><L><R><D><R><S... | Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from straight-chain, 2-methyl-branched-chain fatty acids bile acid intermediates. With EHHADH, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyac... | P51659 |
Q8N456 | LRC18_HUMAN | Leucine-rich repeat-containing protein 18 | Homo | <M><V><K><G><E><K><G><P><K><G><K><K><I><T><L><K><V><A><R><N><C><I><K><I><T><F><D><G><K><K><R><L><D><L><S><K><M><G><I><T><T><F><P><K><C><I><L><R><L><S><D><M><D><E><L><D><L><S><R><N><L><I><R><K><I><P><D><S><I><S><K><F><Q><N><L><R><W><L><D><L><H><S><N><Y><I><D><K><L><P><E><S><I><G><Q><M><T><S><L><L><Y><L><N><V><S><N><N><R... | May be involved in the regulation of spermatogenesis and sperm maturation.<BOP> | Q8N456 |
O15217 | GSTA4_HUMAN | Glutathione S-transferase A4-4 | Homo | <M><A><A><R><P><K><L><H><Y><P><N><G><R><G><R><M><E><S><V><R><W><V><L><A><A><A><G><V><E><F><D><E><E><F><L><E><T><K><E><Q><L><Y><K><L><Q><D><G><N><H><L><L><F><Q><Q><V><P><M><V><E><I><D><G><M><K><L><V><Q><T><R><S><I><L><H><Y><I><A><D><K><H><N><L><F><G><K><N><L><K><E><R><T><L><I><D><M><Y><V><E><G><T><L><D><L><L><E><L><L><I... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE).<BOP> | O15217 |
Q9NW13 | RBM28_HUMAN | RNA-binding motif protein 28 | Homo | <M><A><G><L><T><L><F><V><G><R><L><P><P><S><A><R><S><E><Q><L><E><E><L><F><S><Q><V><G><P><V><K><Q><C><F><V><V><T><E><K><G><S><K><A><C><R><G><F><G><Y><V><T><F><S><M><L><E><D><V><Q><R><A><L><K><E><I><T><T><F><E><G><C><K><I><N><V><T><V><A><K><K><K><L><R><N><K><T><K><E><K><G><K><N><E><N><S><E><C><P><K><K><E><P><K><A><K><K><A... | Nucleolar component of the spliceosomal ribonucleoprotein complexes.<BOP> | Q9NW13 |
Q9ULM6 | CNOT6_HUMAN | Cytoplasmic deadenylase | Homo | <M><P><K><E><K><Y><E><P><P><D><P><R><R><M><Y><T><I><M><S><S><E><E><A><A><N><G><K><K><S><H><W><A><E><L><E><I><S><G><K><V><R><S><L><S><A><S><L><W><S><L><T><H><L><T><A><L><H><L><S><D><N><S><L><S><R><I><P><S><D><I><A><K><L><H><N><L><V><Y><L><D><L><S><S><N><K><I><R><S><L><P><A><E><L><G><N><M><V><S><L><R><E><L><H><L><N><N><N... | Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transc... | Q9ULM6 |
A0A0B4J234 | TVA2_HUMAN | T cell receptor alpha variable 2 | Homo | <M><A><L><Q><S><T><L><G><A><V><W><L><G><L><L><L><N><S><L><W><K><V><A><E><S><K><D><Q><V><F><Q><P><S><T><V><A><S><S><E><G><A><V><V><E><I><F><C><N><H><S><V><S><N><A><Y><N><F><F><W><Y><L><H><F><P><G><C><A><P><R><L><L><V><K><G><S><K><P><S><Q><Q><G><R><Y><N><M><T><Y><E><R><F><S><S><S><L><L><I><L><Q><V><R><E><A><D><A><A><V><Y... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A0B4J234 |
Q9BY77 | PDIP3_HUMAN | S6K1 Aly/REF-like target | Homo | <M><A><D><I><S><L><D><E><L><I><R><K><R><G><A><A><A><K><G><R><L><N><A><R><P><G><V><G><G><V><R><S><R><V><G><I><Q><Q><G><L><L><S><Q><S><T><R><T><A><T><F><Q><Q><R><F><D><A><R><Q><K><I><G><L><S><D><A><R><L><K><L><G><V><K><D><A><R><E><K><L><L><Q><K><D><A><R><F><R><I><K><G><K><V><Q><D><A><R><E><M><L><N><S><R><K><Q><Q><T><T><V... | Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly s... | Q9BY77 |
Q9BRR0 | ZKSC3_HUMAN | Zinc finger protein 47 homolog | Homo | <M><A><R><E><L><S><E><S><T><A><L><D><A><Q><S><T><E><D><Q><M><E><L><L><V><I><K><V><E><E><E><E><A><G><F><P><S><S><P><D><L><G><S><E><G><S><R><E><R><F><R><G><F><R><Y><P><E><A><A><G><P><R><E><A><L><S><R><L><R><E><L><C><R><Q><W><L><Q><P><E><M><H><S><K><E><Q><I><L><E><L><L><V><L><E><Q><F><L><T><I><L><P><G><N><L><Q><S><W><V><R... | Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also act... | Q9BRR0 |
O00623 | PEX12_HUMAN | Peroxisome assembly factor 3 | Homo | <M><A><E><H><G><A><H><F><T><A><A><S><V><A><D><D><Q><P><S><I><F><E><V><V><A><Q><D><S><L><M><T><A><V><R><P><A><L><Q><H><V><V><K><V><L><A><E><S><N><P><T><H><Y><G><F><L><W><R><W><F><D><E><I><F><T><L><L><D><L><L><L><Q><Q><H><Y><L><S><R><T><S><A><S><F><S><E><N><F><Y><G><L><K><R><I><V><M><G><D><T><H><K><S><Q><R><L><A><S><A><G... | Required for protein import into peroxisomes.<BOP> | O00623 |
D6RGH6 | MCIN_HUMAN | Protein Idas | Homo | <M><Q><A><C><G><G><G><A><A><G><R><R><A><F><D><S><I><C><P><N><R><M><L><A><L><P><G><R><A><L><L><C><K><P><G><K><P><E><R><K><F><A><P><P><R><K><F><F><P><G><C><T><G><G><S><P><V><S><V><Y><E><D><P><P><D><A><E><P><T><A><L><P><A><L><T><T><I><D><L><Q><D><L><A><D><C><S><S><L><L><G><S><D><A><P><P><G><G><D><L><A><A><S><Q><N><H><S><H... | Transcription regulator specifically required for multiciliate cell differentiation . Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway . Plays a role in mitotic cell cycle progression by pr... | D6RGH6 |
Q9GZV5 | WWTR1_HUMAN | Transcriptional coactivator with PDZ-binding motif | Homo | <M><N><P><A><S><A><P><P><P><L><P><P><P><G><Q><Q><V><I><H><V><T><Q><D><L><D><T><D><L><E><A><L><F><N><S><V><M><N><P><K><P><S><S><W><R><K><K><I><L><P><E><S><F><F><K><E><P><D><S><G><S><H><S><R><Q><S><S><T><D><S><S><G><G><H><P><G><P><R><L><A><G><G><A><Q><H><V><R><S><H><S><S><P><A><S><L><Q><L><G><T><G><A><G><A><A><G><S><P><A... | Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis . The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, i... | Q9GZV5 |
O75845 | SC5D_HUMAN | Sterol-C5-desaturase | Homo | <M><D><L><V><L><R><V><A><D><Y><Y><F><F><T><P><Y><V><Y><P><A><T><W><P><E><D><D><I><F><R><Q><A><I><S><L><L><I><V><T><N><V><G><A><Y><I><L><Y><F><F><C><A><T><L><S><Y><Y><F><V><F><D><H><A><L><M><K><H><P><Q><F><L><K><N><Q><V><R><R><E><I><K><F><T><V><Q><A><L><P><W><I><S><I><L><T><V><A><L><F><L><L><E><I><R><G><Y><S><K><L><H><D... | Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol in cholesterol biosynthesis.<BOP> | O75845 |
Q86U06 | RBM23_HUMAN | Splicing factor SF2 | Homo | <M><A><S><D><D><F><D><I><V><I><E><A><M><L><E><A><P><Y><K><K><E><E><D><E><Q><Q><R><K><E><V><K><K><D><Y><P><S><N><T><T><S><S><T><S><N><S><G><N><E><T><S><G><S><S><T><I><G><E><T><S><K><K><K><R><S><R><S><H><N><K><S><R><D><R><K><R><S><R><S><R><D><R><D><R><Y><R><R><R><N><S><R><S><R><S><P><G><R><Q><C><R><H><R><S><R><S><W><D><R... | RNA-binding protein that acts both as a transcription coactivator and pre-mRNA splicing factor . Regulates steroid hormone receptor-mediated transcription, independently of the pre-mRNA splicing factor activity .<BOP> | Q86U06 |
O00241 | SIRB1_HUMAN | CD172 antigen-like family member B | Homo | <M><P><V><P><A><S><W><P><H><L><P><S><P><F><L><L><M><T><L><L><L><G><R><L><T><G><V><A><G><E><D><E><L><Q><V><I><Q><P><E><K><S><V><S><V><A><A><G><E><S><A><T><L><R><C><A><M><T><S><L><I><P><V><G><P><I><M><W><F><R><G><A><G><A><G><R><E><L><I><Y><N><Q><K><E><G><H><F><P><R><V><T><T><V><S><E><L><T><K><R><N><N><L><D><F><S><I><S><I... | Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP .<BOP> | O00241 |
Q92637 | FCGRB_HUMAN | Fc-gamma RIB | Homo | <M><W><F><L><T><T><L><L><L><W><V><P><V><D><G><Q><V><D><T><T><K><A><V><I><T><L><Q><P><P><W><V><S><V><F><Q><E><E><T><V><T><L><H><C><E><V><L><H><L><P><G><S><S><S><T><Q><W><F><L><N><G><T><A><T><Q><T><S><T><P><S><Y><R><I><T><S><A><S><V><N><D><S><G><E><Y><R><C><Q><R><G><L><S><G><R><S><D><P><I><Q><L><E><I><H><R><G><W><L><L><L... | May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response.<BOP> | Q92637 |
Q8N2I9 | STK40_HUMAN | Sugen kinase 495 | Homo | <M><K><R><R><A><S><D><R><G><A><G><E><T><S><A><R><A><K><A><L><G><S><G><I><S><G><N><N><A><K><R><A><G><P><F><I><L><G><P><R><L><G><N><S><P><V><P><S><I><V><Q><C><L><A><R><K><D><G><T><D><D><F><Y><Q><L><K><I><L><T><L><E><E><R><G><D><Q><G><I><E><S><Q><E><E><R><Q><G><K><M><L><L><H><T><E><Y><S><L><L><S><L><L><H><T><Q><D><G><V><V... | May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.<BOP> | Q8N2I9 |
Q9NYJ1 | COA4_HUMAN | E2-induced gene 2 protein | Homo | <M><S><T><S><V><P><Q><G><H><T><W><T><Q><R><V><K><K><D><D><E><E><E><D><P><L><D><Q><L><I><S><R><S><G><C><A><A><S><H><F><A><V><Q><E><C><M><A><Q><H><Q><D><W><R><Q><C><Q><P><Q><V><Q><A><F><K><D><C><M><S><E><Q><Q><A><R><R><Q><E><E><L><Q><R><R><Q><E><Q><A><G><A><H><H> | Putative COX assembly factor.<BOP> | Q9NYJ1 |
Q8NGN5 | O10G8_HUMAN | Olfactory receptor OR11-282 | Homo | <M><S><N><A><S><L><L><T><A><F><I><L><M><G><L><P><H><A><P><A><L><D><A><P><L><F><G><V><F><L><V><V><Y><V><L><T><V><L><G><N><L><L><I><L><L><V><I><R><V><D><S><H><L><H><T><T><M><Y><Y><F><L><T><N><L><S><F><I><D><M><W><F><S><T><V><T><V><P><K><L><L><M><T><L><V><F><P><S><G><R><A><I><S><F><H><S><C><M><A><Q><L><Y><F><F><H><F><L><G... | Odorant receptor.<BOP> | Q8NGN5 |
A8MT65 | ZN891_HUMAN | Zinc finger protein 891 | Homo | <M><A><V><M><D><L><S><S><P><W><A><L><T><K><Q><D><S><A><C><F><H><L><R><N><A><E><E><E><R><M><I><A><V><F><L><T><T><W><L><Q><E><P><M><T><F><K><D><V><A><V><E><F><T><Q><E><E><W><M><M><L><D><S><A><Q><R><S><L><Y><R><D><V><M><L><E><N><Y><R><N><L><T><S><V><E><Y><Q><L><Y><R><L><T><V><I><S><P><L><D><Q><E><E><I><R><N><M><K><K><R><I... | May be involved in transcriptional regulation.<BOP> | A8MT65 |
Q15916 | ZBTB6_HUMAN | Zinc finger protein with interaction domain | Homo | <M><A><A><E><S><D><V><L><H><F><Q><F><E><Q><Q><G><D><V><V><L><Q><K><M><N><L><L><R><Q><Q><N><L><F><C><D><V><S><I><Y><I><N><D><T><E><F><Q><G><H><K><V><I><L><A><A><C><S><T><F><M><R><D><Q><F><L><L><T><Q><S><K><H><V><R><I><T><I><L><Q><S><A><E><V><G><R><K><L><L><L><S><C><Y><T><G><A><L><E><V><K><R><K><E><L><L><K><Y><L><T><A><A... | May be involved in transcriptional regulation.<BOP> | Q15916 |
O14576 | DC1I1_HUMAN | Dynein intermediate chain 1, cytosolic | Homo | <M><S><D><K><S><D><L><K><A><E><L><E><R><K><K><Q><R><L><A><Q><I><R><E><E><K><K><R><K><E><E><E><R><K><K><K><E><A><D><M><Q><Q><K><K><E><P><V><Q><D><D><S><D><L><D><R><K><R><R><E><T><E><A><L><L><Q><S><I><G><I><S><P><E><P><P><L><V><Q><P><L><H><F><L><T><W><D><T><C><Y><F><H><Y><L><V><P><T><P><M><S><P><S><S><K><S><V><S><T><P><S... | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along... | O14576 |
Q7L9L4 | MOB1B_HUMAN | Mps one binder kinase activator-like 1A | Homo | <M><S><F><L><F><G><S><R><S><S><K><T><F><K><P><K><K><N><I><P><E><G><S><H><Q><Y><E><L><L><K><H><A><E><A><T><L><G><S><G><N><L><R><M><A><V><M><L><P><E><G><E><D><L><N><E><W><V><A><V><N><T><V><D><F><F><N><Q><I><N><M><L><Y><G><T><I><T><D><F><C><T><E><E><S><C><P><V><M><S><A><G><P><K><Y><E><Y><H><W><A><D><G><T><N><I><K><K><P><I... | Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphor... | Q7L9L4 |
P22748 | CAH4_HUMAN | Carbonic anhydrase IV | Homo | <M><R><M><L><L><A><L><L><A><L><S><A><A><R><P><S><A><S><A><E><S><H><W><C><Y><E><V><Q><A><E><S><S><N><Y><P><C><L><V><P><V><K><W><G><G><N><C><Q><K><D><R><Q><S><P><I><N><I><V><T><T><K><A><K><V><D><K><K><L><G><R><F><F><F><S><G><Y><D><K><K><Q><T><W><T><V><Q><N><N><G><H><S><V><M><M><L><L><E><N><K><A><S><I><S><G><G><G><L><P><A... | Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH . May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis . It is essential for acid overload removal from the retina and reti... | P22748 |
Q9UK32 | KS6A6_HUMAN | pp90RSK4 | Homo | <M><L><P><F><A><P><Q><D><E><P><W><D><R><E><M><E><V><F><S><G><G><G><A><S><S><G><E><V><N><G><L><K><M><V><D><E><P><M><E><E><G><E><A><D><S><C><H><D><E><G><V><V><K><E><I><P><I><T><H><H><V><K><E><G><Y><E><K><A><D><P><A><Q><F><E><L><L><K><V><L><G><Q><G><S><F><G><K><V><F><L><V><R><K><K><T><G><P><D><A><G><Q><L><Y><A><M><K><V><L... | Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.<BOP> | Q9UK32 |
A0A539 | TVB42_HUMAN | T cell receptor beta variable 4-2 | Homo | <M><G><C><R><L><L><C><C><A><V><L><C><L><L><G><A><V><P><M><E><T><G><V><T><Q><T><P><R><H><L><V><M><G><M><T><N><K><K><S><L><K><C><E><Q><H><L><G><H><N><A><M><Y><W><Y><K><Q><S><A><K><K><P><L><E><L><M><F><V><Y><N><F><K><E><Q><T><E><N><N><S><V><P><S><R><F><S><P><E><C><P><N><S><S><H><L><F><L><H><L><H><T><L><Q><P><E><D><S><A><L... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A539 |
Q7L190 | DPPA4_HUMAN | Developmental pluripotency-associated protein 4 | Homo | <M><L><R><G><S><A><S><S><T><S><M><E><K><A><K><G><K><E><W><T><S><T><E><K><S><R><E><E><D><Q><Q><A><S><N><Q><P><N><S><I><A><L><P><G><T><S><A><K><R><T><K><E><K><M><S><I><K><G><S><K><V><L><C><P><K><K><K><A><E><H><T><D><N><P><R><P><Q><K><K><I><P><I><P><P><L><P><S><K><L><P><P><V><N><L><I><H><R><D><I><L><R><A><W><C><Q><Q><L><K... | May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.<BOP> | Q7L190 |
Q9UPQ4 | TRI35_HUMAN | Hemopoietic lineage switch protein 5 | Homo | <M><E><R><S><P><D><V><S><P><G><P><S><R><S><F><K><E><E><L><L><C><A><V><C><Y><D><P><F><R><D><A><V><T><L><R><C><G><H><N><F><C><R><G><C><V><S><R><C><W><E><V><Q><V><S><P><T><C><P><V><C><K><D><R><A><S><P><A><D><L><R><T><N><H><T><L><N><N><L><V><E><K><L><L><R><E><E><A><E><G><A><R><W><T><S><Y><R><F><S><R><V><C><R><L><H><R><G><Q... | E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response. Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via DDX58/RIG-I signaling pathway . Can also catalyz... | Q9UPQ4 |
O43148 | MCES_HUMAN | mRNA cap methyltransferase | Homo | <M><A><N><S><A><K><A><E><E><Y><E><K><M><S><L><E><Q><A><K><A><S><V><N><S><E><T><E><S><S><F><N><I><N><E><N><T><T><A><S><G><T><G><L><S><E><K><T><S><V><C><R><Q><V><D><I><A><R><K><R><K><E><F><E><D><D><L><V><K><E><S><S><S><C><G><K><D><T><P><S><K><K><R><K><L><D><P><E><I><V><P><E><E><K><D><C><G><D><A><E><G><N><S><K><K><R><K><R... | Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs . Binds RNA containing 5'-terminal GpppC .<BOP> | O43148 |
A8MXU0 | DB108_HUMAN | Putative beta-defensin 108B pseudogene 1/2 | Homo | <M><R><I><A><V><L><F><F><T><I><F><F><F><M><S><Q><V><L><P><A><K><G><K><F><K><E><I><C><E><R><P><N><G><S><C><R><D><F><C><L><E><T><E><I><H><V><G><R><C><L><N><S><R><P><C><C><L><P><L><G><H><Q><P><R><I><E><S><T><T><P><K><K><D> | Has antibacterial activity.<BOP> | A8MXU0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.