accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q9BW66 | CINP_HUMAN | Cyclin-dependent kinase 2-interacting protein | Homo | <M><E><A><K><T><L><G><T><V><T><P><R><K><P><V><L><S><V><S><A><R><K><I><K><D><N><A><A><D><W><H><N><L><I><L><K><W><E><T><L><N><D><A><G><F><T><T><A><N><N><I><A><N><L><K><I><S><L><L><N><K><D><K><I><E><L><D><S><S><S><P><A><S><K><E><N><E><E><K><V><C><L><E><Y><N><E><E><L><E><K><L><C><E><E><L><Q><A><T><L><D><G><L><T><K><I><Q><V... | Component of the DNA replication complex, which interacts with two kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication . Regulates ATR-mediated checkpoint signaling in response to DNA damage . Also involved in the cytoplasmic maturat... | Q9BW66 |
Q96NG8 | ZN582_HUMAN | Zinc finger protein 582 | Homo | <M><S><L><G><S><E><L><F><R><D><V><A><I><V><F><S><Q><E><E><W><Q><W><L><A><P><A><Q><R><D><L><Y><R><D><V><M><L><E><T><Y><S><N><L><V><S><L><G><L><A><V><S><K><P><D><V><I><S><F><L><E><Q><G><K><E><P><W><M><V><E><R><V><V><S><G><G><L><C><P><V><L><E><S><R><Y><D><T><K><E><L><F><P><K><Q><H><V><Y><E><V><E><S><P><Q><W><E><I><M><E><S... | May be involved in transcriptional regulation.<BOP> | Q96NG8 |
P30049 | ATPD_HUMAN | F-ATPase delta subunit | Homo | <M><L><P><A><A><L><L><R><R><P><G><L><G><R><L><V><R><H><A><R><A><Y><A><E><A><A><A><A><P><A><A><A><S><G><P><N><Q><M><S><F><T><F><A><S><P><T><Q><V><F><F><N><G><A><N><V><R><Q><V><D><V><P><T><L><T><G><A><F><G><I><L><A><A><H><V><P><T><L><Q><V><L><R><P><G><L><V><V><V><H><A><E><D><G><T><T><S><K><Y><F><V><S><S><G><S><I><A><V><N... | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain . F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous c... | P30049 |
Q13487 | SNPC2_HUMAN | snRNA-activating protein complex 45 kDa subunit | Homo | <M><K><P><P><P><R><R><R><A><A><P><A><R><Y><L><G><E><V><T><G><P><A><T><W><S><A><R><E><K><R><Q><L><V><R><L><L><Q><A><R><Q><G><Q><P><E><P><D><A><T><E><L><A><R><E><L><R><G><R><S><E><A><E><I><R><V><F><L><Q><Q><L><K><G><R><V><A><R><E><A><I><Q><K><V><H><P><G><G><L><Q><G><P><R><R><R><E><A><Q><P><P><A><P><I><E><V><W><T><D><L><A... | Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.<BOP> | Q13487 |
P0DJD7 | PEPA4_HUMAN | Pepsinogen-4 | Homo | <M><K><W><L><L><L><L><G><L><V><A><L><S><E><C><I><M><Y><K><V><P><L><I><R><K><K><S><L><R><R><T><L><S><E><R><G><L><L><K><D><F><L><K><K><H><N><L><N><P><A><R><K><Y><F><P><Q><W><E><A><P><T><L><V><D><E><Q><P><L><E><N><Y><L><D><M><E><Y><F><G><T><I><G><I><G><T><P><A><Q><D><F><T><V><V><F><D><T><G><S><S><N><L><W><V><P><S><V><Y><C... | Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.<BOP> | P0DJD7 |
Q9HAD4 | WDR41_HUMAN | WD repeat-containing protein 41 | Homo | <M><L><R><W><L><I><G><G><G><R><E><P><Q><G><L><A><E><K><S><P><L><Q><T><I><G><E><E><Q><T><Q><N><P><Y><T><E><L><L><V><L><K><A><H><H><D><I><V><R><F><L><V><Q><L><D><D><Y><R><F><A><S><A><G><D><D><G><I><V><V><V><W><N><A><Q><T><G><E><K><L><L><E><L><N><G><H><T><Q><K><I><T><A><I><I><T><F><P><S><L><E><S><C><E><E><K><N><Q><L><I><L... | Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy . The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophago... | Q9HAD4 |
Q92552 | RT27_HUMAN | Mitochondrial small ribosomal subunit protein mS27 | Homo | <M><A><A><S><I><V><R><R><G><M><L><L><A><R><Q><V><V><L><P><Q><L><S><P><A><G><K><R><Y><L><L><S><S><A><Y><V><D><S><H><K><W><E><A><R><E><K><E><H><Y><C><L><A><D><L><A><S><L><M><D><K><T><F><E><R><K><L><P><V><S><S><L><T><I><S><R><L><I><D><N><I><S><S><R><E><E><I><D><H><A><E><Y><Y><L><Y><K><F><R><H><S><P><N><C><W><Y><L><R><N><W... | RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis . Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain . Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu) . Involved al... | Q92552 |
G5E9R7 | KR416_HUMAN | Keratin-associated protein 4-16 pseudogene | Homo | <M><C><S><S><K><M><P><C><S><P><S><A><S><S><L><C><A><A><S><P><P><N><C><C><H><P><S><C><C><Q><T><T><C><C><R><T><T><S><C><S><H><S><C><S><V><S><S><C><C><R><P><Q><C><C><H><S><V><C><C><Q><P><T><C><C><R><P><S><C><C><Q><T><T><C><C><R><T><T><C><C><H><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><H><S><V><C><F><Q><P><T><C><C><H><P><S... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | G5E9R7 |
Q96DY2 | DRC10_HUMAN | IQ domain-containing protein D | Homo | <M><A><L><D><I><L><A><M><A><P><L><Y><Q><A><P><A><I><N><R><I><G><P><K><T><D><P><S><K><R><P><A><D><P><L><K><P><L><V><L><S><R><T><K><L><T><T><I><E><A><K><R><I><M><S><I><L><D><E><A><I><Y><K><V><E><L><V><T><L><L><S><Y><V><A><S><N><R><E><D><M><E><G><M><L><G><E><D><V><M><R><A><V><R><E><H><E><D><L><C><Q><V><L><L><E><N><V><R><C... | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.<BOP> | Q96DY2 |
Q8NGS0 | OR1N1_HUMAN | Olfactory receptor OR9-22 | Homo | <M><E><N><Q><S><S><I><S><E><F><F><L><R><G><I><S><A><P><P><E><Q><Q><Q><S><L><F><G><I><F><L><C><M><Y><L><V><T><L><T><G><N><L><L><I><I><L><A><I><G><S><D><L><H><L><H><T><P><M><Y><F><F><L><A><N><L><S><F><V><D><M><G><L><T><S><S><T><V><T><K><M><L><V><N><I><Q><T><R><H><H><T><I><S><Y><T><G><C><L><T><Q><M><Y><F><F><L><M><F><G><D... | Odorant receptor.<BOP> | Q8NGS0 |
Q9H503 | BAFL_HUMAN | Barrier-to-autointegration factor 2 | Homo | <M><D><N><M><S><P><R><L><R><A><F><L><S><E><P><I><G><E><K><D><V><C><W><V><D><G><I><S><H><E><L><A><I><N><L><V><T><K><G><I><N><K><A><Y><I><L><L><G><Q><F><L><L><M><H><K><N><E><A><E><F><Q><R><W><L><I><C><C><F><G><A><T><E><C><E><A><Q><Q><T><S><H><C><L><K><E><W><C><A><C><F><L> | May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.<BOP> | Q9H503 |
O00219 | HYAS3_HUMAN | Hyaluronic acid synthase 3 | Homo | <M><P><V><Q><L><T><T><A><L><R><V><V><G><T><S><L><F><A><L><A><V><L><G><G><I><L><A><A><Y><V><T><G><Y><Q><F><I><H><T><E><K><H><Y><L><S><F><G><L><Y><G><A><I><L><G><L><H><L><L><I><Q><S><L><F><A><F><L><E><H><R><R><M><R><R><A><G><Q><A><L><K><L><P><S><P><R><R><G><S><V><A><L><C><I><A><A><Y><Q><E><D><P><D><Y><L><R><K><C><L><R><S... | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of ... | O00219 |
Q9Y274 | SIA10_HUMAN | Sialyltransferase 10 | Homo | <M><R><G><Y><L><V><A><I><F><L><S><A><V><F><L><Y><Y><V><L><H><C><I><L><W><G><T><N><V><Y><W><V><A><P><V><E><M><K><R><R><N><K><I><Q><P><C><L><S><K><P><A><F><A><S><L><L><R><F><H><Q><F><H><P><F><L><C><A><A><D><F><R><K><I><A><S><L><Y><G><S><D><K><F><D><L><P><Y><G><M><R><T><S><A><E><Y><F><R><L><A><L><S><K><L><Q><S><C><D><L><F... | Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylcer... | Q9Y274 |
P01584 | IL1B_HUMAN | Catabolin | Homo | <M><A><E><V><P><E><L><A><S><E><M><M><A><Y><Y><S><G><N><E><D><D><L><F><F><E><A><D><G><P><K><Q><M><K><C><S><F><Q><D><L><D><L><C><P><L><D><G><G><I><Q><L><R><I><S><D><H><H><Y><S><K><G><F><R><Q><A><A><S><V><V><V><A><M><D><K><L><R><K><M><L><V><P><C><P><Q><T><F><Q><E><N><D><L><S><T><F><F><P><F><I><F><E><E><E><P><I><F><F><D><T... | Potent pro-inflammatory cytokine . Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production . Promotes Th17 different... | P01584 |
Q32P51 | RA1L2_HUMAN | hnRNP core protein A1-like 2 | Homo | <M><S><K><S><A><S><P><K><E><P><E><Q><L><R><K><L><F><I><G><G><L><S><F><E><T><T><D><E><S><L><R><S><H><F><E><Q><W><G><T><L><T><D><C><V><V><M><R><D><P><N><T><K><R><S><R><G><F><G><F><V><T><Y><A><T><V><E><E><V><D><A><A><M><N><T><T><P><H><K><V><D><G><R><V><V><E><P><K><R><A><V><S><R><E><D><S><Q><R><P><G><A><H><L><T><V><K><K><I... | Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection.<BOP> | Q32P51 |
Q9Y662 | HS3SB_HUMAN | Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1 | Homo | <M><G><Q><R><L><S><G><G><R><S><C><L><D><V><P><G><R><L><L><P><Q><P><P><P><P><P><P><P><V><R><R><K><L><A><L><L><F><A><M><L><C><V><W><L><Y><M><F><L><Y><S><C><A><G><S><C><A><A><A><P><G><L><L><L><L><G><S><G><S><R><A><A><H><D><P><P><A><L><A><T><A><P><D><G><T><P><P><R><L><P><F><R><A><P><P><A><T><P><L><A><S><G><K><E><M><A><E><G... | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate . Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 . The substrate-specific O-s... | Q9Y662 |
P35367 | HRH1_HUMAN | Histamine H1 receptor | Homo | <M><S><L><P><N><S><S><C><L><L><E><D><K><M><C><E><G><N><K><T><T><M><A><S><P><Q><L><M><P><L><V><V><V><L><S><T><I><C><L><V><T><V><G><L><N><L><L><V><L><Y><A><V><R><S><E><R><K><L><H><T><V><G><N><L><Y><I><V><S><L><S><V><A><D><L><I><V><G><A><V><V><M><P><M><N><I><L><Y><L><L><M><S><K><W><S><L><G><R><P><L><C><L><F><W><L><S><M><D... | In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.<BOP> | P35367 |
Q5T230 | UTF1_HUMAN | Undifferentiated embryonic cell transcription factor 1 | Homo | <M><L><L><R><P><R><R><P><P><P><L><A><P><P><A><P><P><S><P><A><S><P><D><P><E><P><R><T><P><G><D><A><P><G><T><P><P><R><R><P><A><S><P><S><A><L><G><E><L><G><L><P><V><S><P><G><S><A><Q><R><T><P><W><S><A><R><E><T><E><L><L><L><G><T><L><L><Q><P><A><V><W><R><A><L><L><L><D><R><R><Q><A><L><P><T><Y><R><R><V><S><A><A><L><A><Q><Q><Q><V... | Acts as a transcriptional coactivator of ATF2.<BOP> | Q5T230 |
Q13572 | ITPK1_HUMAN | Inositol 1,3,4-trisphosphate 5/6-kinase | Homo | <M><Q><T><F><L><K><G><K><R><V><G><Y><W><L><S><E><K><K><I><K><K><L><N><F><Q><A><F><A><E><L><C><R><K><R><G><M><E><V><V><Q><L><N><L><S><R><P><I><E><E><Q><G><P><L><D><V><I><I><H><K><L><T><D><V><I><L><E><A><D><Q><N><D><S><Q><S><L><E><L><V><H><R><F><Q><E><Y><I><D><A><H><P><E><T><I><V><L><D><P><L><P><A><I><R><T><L><L><D><R><S... | Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 . Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5 . This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, wh... | Q13572 |
O95971 | BY55_HUMAN | CD160 antigen, soluble form | Homo | <M><L><L><E><P><G><R><G><C><C><A><L><A><I><L><L><A><I><V><D><I><Q><S><G><G><C><I><N><I><T><S><S><A><S><Q><E><G><T><R><L><N><L><I><C><T><V><W><H><K><K><E><E><A><E><G><F><V><V><F><L><C><K><D><R><S><G><D><C><S><P><E><T><S><L><K><Q><L><R><L><K><R><D><P><G><I><D><G><V><G><E><I><S><S><Q><L><M><F><T><I><S><Q><V><T><P><L><H><S... | The soluble GPI-cleaved form, usually released by activated lymphocytes, might play an immune regulatory role by limiting lymphocyte effector functions.<BOP> | O95971 |
Q6P4F1 | FUT10_HUMAN | Galactoside 3-L-fucosyltransferase 10 | Homo | <M><V><R><I><Q><R><R><K><L><L><A><S><C><L><C><V><T><A><T><V><F><L><L><V><T><L><Q><V><M><V><E><L><G><K><F><E><R><K><E><F><K><S><S><S><L><Q><D><G><H><T><K><M><E><E><A><P><T><H><L><N><S><F><L><K><K><E><G><L><T><F><N><R><K><R><K><W><E><L><D><S><Y><P><I><M><L><W><W><S><P><L><T><G><E><T><G><R><L><G><Q><C><G><A><D><A><C><F><F... | Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit.<BOP> | Q6P4F1 |
P02656 | APOC3_HUMAN | Apolipoprotein C3 | Homo | <M><Q><P><R><V><L><L><V><V><A><L><L><A><L><L><A><S><A><R><A><S><E><A><E><D><A><S><L><L><S><F><M><Q><G><Y><M><K><H><A><T><K><T><A><K><D><A><L><S><S><V><Q><E><S><Q><V><A><Q><Q><A><R><G><W><V><T><D><G><F><S><S><L><K><D><Y><W><S><T><V><K><D><K><F><S><E><F><W><D><L><D><P><E><V><R><P><T><S><A><V><A><A> | Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma . Plays a multifaceted role in triglyceride homeostasis . Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearanc... | P02656 |
Q9BS26 | ERP44_HUMAN | Thioredoxin domain-containing protein 4 | Homo | <M><H><P><A><V><F><L><S><L><P><D><L><R><C><S><L><L><L><L><V><T><W><V><F><T><P><V><T><T><E><I><T><S><L><D><T><E><N><I><D><E><I><L><N><N><A><D><V><A><L><V><N><F><Y><A><D><W><C><R><F><S><Q><M><L><H><P><I><F><E><E><A><S><D><V><I><K><E><E><F><P><N><E><N><Q><V><V><F><A><R><V><D><C><D><Q><H><S><D><I><A><Q><R><Y><R><I><S><K><Y... | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif . Inhibits the calcium channel activity of ITPR1 . May have a role in the control of oxidative protein folding in the endoplasmic reticulum . Required to retain ERO1A and ... | Q9BS26 |
Q99757 | THIOM_HUMAN | Thioredoxin-2 | Homo | <M><A><Q><R><L><L><L><R><R><F><L><A><S><V><I><S><R><K><P><S><Q><G><Q><W><P><P><L><T><S><R><A><L><Q><T><P><Q><C><S><P><G><G><L><T><V><T><P><N><P><A><R><T><I><Y><T><T><R><I><S><L><T><T><F><N><I><Q><D><G><P><D><F><Q><D><R><V><V><N><S><E><T><P><V><V><V><D><F><H><A><Q><W><C><G><P><C><K><I><L><G><P><R><L><E><K><M><V><A><K><Q... | Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.<BOP> | Q99757 |
P20290 | BTF3_HUMAN | RNA polymerase B transcription factor 3 | Homo | <M><R><R><T><G><A><P><A><Q><A><D><S><R><G><R><G><R><A><R><G><G><C><P><G><G><E><A><T><L><S><Q><P><P><P><R><G><G><T><R><G><Q><E><P><Q><M><K><E><T><I><M><N><Q><E><K><L><A><K><L><Q><A><Q><V><R><I><G><G><K><G><T><A><R><R><K><K><K><V><V><H><R><T><A><T><A><D><D><K><K><L><Q><F><S><L><K><K><L><G><V><N><N><I><S><G><I><E><E><V><N... | When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to ... | P20290 |
Q7Z7B7 | DB132_HUMAN | Defensin, beta 132 | Homo | <M><K><F><L><L><L><V><L><A><A><L><G><F><L><T><Q><V><I><P><A><S><A><G><G><S><K><C><V><S><N><T><P><G><Y><C><R><T><C><C><H><W><G><E><T><A><L><F><M><C><N><A><S><R><K><C><C><I><S><Y><S><F><L><P><K><P><D><L><P><Q><L><I><G><N><H><W><Q><S><R><R><R><N><T><Q><R><K><D><K><K><Q><Q><T><T><V><T><S> | Has antibacterial activity.<BOP> | Q7Z7B7 |
P56937 | DHB7_HUMAN | Short chain dehydrogenase/reductase family 37C member 1 | Homo | <M><R><K><V><V><L><I><T><G><A><S><S><G><I><G><L><A><L><C><K><R><L><L><A><E><D><D><E><L><H><L><C><L><A><C><R><N><M><S><K><A><E><A><V><C><A><A><L><L><A><S><H><P><T><A><E><V><T><I><V><Q><V><D><V><S><N><L><Q><S><V><F><R><A><S><K><E><L><K><Q><R><F><Q><R><L><D><C><I><Y><L><N><A><G><I><M><P><N><P><Q><L><N><I><K><A><L><F><F><G... | Does not have enzymatic activities toward E1 and DHT.<BOP> | P56937 |
Q86TX2 | ACOT1_HUMAN | Palmitoyl-coenzyme A thioesterase | Homo | <M><A><A><T><L><I><L><E><P><A><G><R><C><C><W><D><E><P><V><R><I><A><V><R><G><L><A><P><E><Q><P><V><T><L><R><A><S><L><R><D><E><K><G><A><L><F><Q><A><H><A><R><Y><R><A><D><T><L><G><E><L><D><L><E><R><A><P><A><L><G><G><S><F><A><G><L><E><P><M><G><L><L><W><A><L><E><P><E><K><P><L><V><R><L><V><K><R><D><V><R><T><P><L><A><V><E><L><E... | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20).<BOP> | Q86TX2 |
O60884 | DNJA2_HUMAN | Renal carcinoma antigen NY-REN-14 | Homo | <M><A><N><V><A><D><T><K><L><Y><D><I><L><G><V><P><P><G><A><S><E><N><E><L><K><K><A><Y><R><K><L><A><K><E><Y><H><P><D><K><N><P><N><A><G><D><K><F><K><E><I><S><F><A><Y><E><V><L><S><N><P><E><K><R><E><L><Y><D><R><Y><G><E><Q><G><L><R><E><G><S><G><G><G><G><G><M><D><D><I><F><S><H><I><F><G><G><G><L><F><G><F><M><G><N><Q><S><R><S><R... | Co-chaperone of Hsc70. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) .<BOP> | O60884 |
O95704 | APBB3_HUMAN | Protein Fe65-like 2 | Homo | <M><L><G><K><D><Y><M><L><A><I><I><L><V><N><C><D><D><D><L><W><G><D><H><S><L><E><V><E><A><G><L><P><P><G><W><R><K><I><H><D><A><A><G><T><Y><Y><W><H><V><P><S><G><S><T><Q><W><Q><R><P><T><W><E><L><G><D><A><E><D><P><G><T><G><T><E><G><I><W><G><L><R><P><P><K><G><R><S><F><S><S><L><E><S><S><L><D><R><S><N><S><L><S><W><Y><G><G><E><S... | May modulate the internalization of amyloid-beta precursor protein.<BOP> | O95704 |
Q6L8H4 | KRA51_HUMAN | Ultrahigh sulfur keratin-associated protein 5.1 | Homo | <M><G><C><C><G><C><S><G><G><C><G><S><S><C><G><G><C><G><S><G><C><G><G><C><G><S><G><C><G><G><C><G><S><G><C><G><G><S><G><S><S><C><C><V><P><V><C><C><C><K><P><V><C><C><R><V><P><T><C><S><C><S><S><C><G><K><G><G><C><G><S><S><G><G><S><K><G><G><C><G><S><C><G><G><C><K><G><G><C><G><S><C><G><G><S><K><G><G><C><G><S><C><G><G><S><K><G... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hai... | Q6L8H4 |
Q99259 | DCE1_HUMAN | Glutamate decarboxylase 67 kDa isoform | Homo | <M><A><S><S><T><P><S><S><S><A><T><S><S><N><A><G><A><D><P><N><T><T><N><L><R><P><T><T><Y><D><T><W><C><G><V><A><H><G><C><T><R><K><L><G><L><K><I><C><G><F><L><Q><R><T><N><S><L><E><E><K><S><R><L><V><S><A><F><K><E><R><Q><S><S><K><N><L><L><S><C><E><N><S><D><R><D><A><R><F><R><R><T><E><T><D><F><S><N><L><F><A><R><D><L><L><P><A><K... | Enzymatically inactive as glutamate decarboxylase.<BOP> | Q99259 |
Q9NV23 | SAST_HUMAN | Thioesterase domain-containing protein 1 | Homo | <M><E><R><G><D><Q><P><K><R><T><R><N><E><N><I><F><N><C><L><Y><K><N><P><E><A><T><F><K><L><I><C><F><P><W><M><G><G><G><S><T><H><F><A><K><W><G><Q><D><T><H><D><L><L><E><V><H><S><L><R><L><P><G><R><E><S><R><V><E><E><P><L><E><N><D><I><S><Q><L><V><D><E><V><V><C><A><L><Q><P><V><I><Q><D><K><P><F><A><F><F><G><H><S><M><G><S><Y><I><A... | Contributes to the release of free fatty acids from fatty acid synthase (FASN). Has broad substrate specificity, giving rise to a range of free fatty acids with chain lengths between 10 and 16 carbon atoms (C10 - C16).<BOP> | Q9NV23 |
O75764 | TCEA3_HUMAN | Transcription elongation factor TFIIS.h | Homo | <M><G><Q><E><E><E><L><L><R><I><A><K><K><L><E><K><M><V><A><R><K><N><T><E><G><A><L><D><L><L><K><K><L><H><S><C><Q><M><S><I><Q><L><L><Q><T><T><R><I><G><V><A><V><N><G><V><R><K><H><C><S><D><K><E><V><V><S><L><A><K><V><L><I><K><N><W><K><R><L><L><D><S><P><G><P><P><K><G><E><K><G><E><E><R><E><K><A><K><K><K><E><K><G><L><E><C><S><D... | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows ... | O75764 |
Q9UK58 | CCNL1_HUMAN | Cyclin-L1 | Homo | <M><A><S><G><P><H><S><T><A><T><A><A><A><A><A><S><S><A><A><P><S><A><G><G><S><S><S><G><T><T><T><T><T><T><T><T><T><G><G><I><L><I><G><D><R><L><Y><S><E><V><S><L><T><I><D><H><S><L><I><P><E><E><R><L><S><P><T><P><S><M><Q><D><G><L><D><L><P><S><E><T><D><L><R><I><L><G><C><E><L><I><Q><A><A><G><I><L><L><R><L><P><Q><V><A><M><A><T><G... | Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) . Inhibited by the CDK-specific inhibitor CDKN1A/p21 . May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) .<BOP> | Q9UK58 |
O75019 | LIRA1_HUMAN | Leukocyte immunoglobulin-like receptor 6 | Homo | <M><T><P><I><V><T><V><L><I><C><L><R><L><S><L><G><P><R><T><H><V><Q><A><G><T><L><P><K><P><T><L><W><A><E><P><G><S><V><I><T><Q><G><S><P><V><T><L><W><C><Q><G><I><L><E><T><Q><E><Y><R><L><Y><R><E><K><K><T><A><P><W><I><T><R><I><P><Q><E><I><V><K><K><G><Q><F><P><I><P><S><I><T><W><E><H><T><G><R><Y><R><C><F><Y><G><S><H><T><A><G><W... | May act as receptor for class I MHC antigens.<BOP> | O75019 |
Q8N6D2 | RN182_HUMAN | RING-type E3 ubiquitin transferase RNF182 | Homo | <M><A><S><Q><P><P><E><D><T><A><E><S><Q><A><S><D><E><L><E><C><K><I><C><Y><N><R><Y><N><L><K><Q><R><K><P><K><V><L><E><C><C><H><R><V><C><A><K><C><L><Y><K><I><I><D><F><G><D><S><P><Q><G><V><I><V><C><P><F><C><R><F><E><T><C><L><P><D><D><E><V><S><S><L><P><D><D><N><N><I><L><V><N><L><T><C><G><G><K><G><K><K><C><L><P><E><N><P><T><E... | E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway . Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA .<B... | Q8N6D2 |
O43396 | TXNL1_HUMAN | 32 kDa thioredoxin-related protein | Homo | <M><V><G><V><K><P><V><G><S><D><P><D><F><Q><P><E><L><S><G><A><G><S><R><L><A><V><V><K><F><T><M><R><G><C><G><P><C><L><R><I><A><P><A><F><S><S><M><S><N><K><Y><P><Q><A><V><F><L><E><V><D><V><H><Q><C><Q><G><T><A><A><T><N><N><I><S><A><T><P><T><F><L><F><F><R><N><K><V><R><I><D><Q><Y><Q><G><A><D><A><V><G><L><E><E><K><I><K><Q><H><L... | Active thioredoxin with a redox potential of about -250 mV.<BOP> | O43396 |
P25189 | MYP0_HUMAN | Myelin protein zero | Homo | <M><A><P><G><A><P><S><S><S><P><S><P><I><L><A><V><L><L><F><S><S><L><V><L><S><P><A><Q><A><I><V><V><Y><T><D><R><E><V><H><G><A><V><G><S><R><V><T><L><H><C><S><F><W><S><S><E><W><V><S><D><D><I><S><F><T><W><R><Y><Q><P><E><G><G><R><D><A><I><S><I><F><H><Y><A><K><G><Q><P><Y><I><D><E><V><G><T><F><K><E><R><I><Q><W><V><G><D><P><R><W... | Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.<BOP> | P25189 |
Q6L8G5 | KR510_HUMAN | Ultrahigh sulfur keratin-associated protein 5.10 | Homo | <M><G><C><C><G><C><S><G><G><C><G><S><G><C><G><G><C><G><S><G><C><G><G><C><G><S><G><C><G><G><Y><G><S><G><C><G><G><C><G><S><S><C><C><V><P><V><C><C><C><K><P><V><C><C><C><V><P><A><C><S><C><S><S><C><G><S><C><G><G><S><K><G><D><C><G><S><C><G><G><S><K><G><G><C><G><S><C><G><G><S><K><G><G><C><G><S><C><G><G><S><K><G><G><C><G><S><C... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hai... | Q6L8G5 |
Q6NVY1 | HIBCH_HUMAN | 3-hydroxyisobutyryl-coenzyme A hydrolase | Homo | <M><G><Q><R><E><M><W><R><L><M><S><R><F><N><A><F><K><R><T><N><T><I><L><H><H><L><R><M><S><K><H><T><D><A><A><E><E><V><L><L><E><K><K><G><C><T><G><V><I><T><L><N><R><P><K><F><L><N><A><L><T><L><N><M><I><R><Q><I><Y><P><Q><L><K><K><W><E><Q><D><P><E><T><F><L><I><I><I><K><G><A><G><G><K><A><F><C><A><G><G><D><I><R><V><I><S><E><A><E... | Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.<BOP> | Q6NVY1 |
Q15622 | OR7A5_HUMAN | Olfactory receptor TPCR92 | Homo | <M><E><P><G><N><D><T><Q><I><S><E><F><L><L><L><G><F><S><Q><E><P><G><L><Q><P><F><L><F><G><L><F><L><S><M><Y><L><V><T><V><L><G><N><L><L><I><I><L><A><T><I><S><D><S><H><L><H><T><P><M><Y><F><F><L><S><N><L><S><F><A><D><I><C><V><T><S><T><T><I><P><K><M><L><M><N><I><Q><T><Q><N><K><V><I><T><Y><I><A><C><L><M><Q><M><Y><F><F><I><L><F... | Odorant receptor.<BOP> | Q15622 |
Q86Z20 | CC125_HUMAN | Protein kenae | Homo | <M><S><K><V><A><R><S><S><S><E><S><D><V><Q><L><W><E><T><E><E><D><D><M><T><E><G><D><L><G><Y><G><L><G><R><K><P><G><G><I><Y><E><I><E><F><S><H><R><S><R><K><R><S><D><G><K><N><F><S><P><P><P><F><P><R><K><G><E><E><R><N><E><A><S><F><Q><Y><S><K><H><K><S><Q><Q><D><T><F><P><Q><V><S><R><I><S><N><Y><R><R><Q><S><S><T><V><D><S><N><S><E... | May be involved in the regulation of cell migration.<BOP> | Q86Z20 |
Q14684 | RRP1B_HUMAN | RRP1-like protein B | Homo | <M><A><P><A><M><Q><P><A><E><I><Q><F><A><Q><R><L><A><S><S><E><K><G><I><R><D><R><A><V><K><K><L><R><Q><Y><I><S><V><K><T><Q><R><E><T><G><G><F><S><Q><E><E><L><L><K><I><W><K><G><L><F><Y><C><M><W><V><Q><D><E><P><L><L><Q><E><E><L><A><N><T><I><A><Q><L><V><H><A><V><N><N><S><A><A><Q><H><L><F><I><Q><T><F><W><Q><T><M><N><R><E><W><K... | (Microbial infection) Following influenza A virus (IAV) infection, promotes viral mRNA transcription by facilitating the binding of IAV RNA-directed RNA polymerase to capped mRNA.<BOP> | Q14684 |
Q8NGG7 | OR8A1_HUMAN | Olfactory receptor OR11-318 | Homo | <M><G><F><L><S><P><M><H><P><C><R><P><P><T><Q><R><R><M><A><A><G><N><H><S><T><V><T><E><F><I><L><K><G><L><T><K><R><A><D><L><Q><L><P><L><F><L><L><F><L><G><I><Y><L><V><T><I><V><G><N><L><G><M><I><T><L><I><C><L><N><S><Q><L><H><T><P><M><Y><Y><F><L><S><N><L><S><L><M><D><L><C><Y><S><S><V><I><T><P><K><M><L><V><N><F><V><S><E><K><N... | Odorant receptor.<BOP> | Q8NGG7 |
Q9H3R5 | CENPH_HUMAN | Interphase centromere complex protein 35 | Homo | <M><E><E><Q><P><Q><M><Q><D><A><D><E><P><A><D><S><G><G><E><G><R><A><G><G><P><P><Q><V><A><G><A><Q><A><A><C><S><E><D><R><M><T><L><L><L><R><L><R><A><Q><T><K><Q><Q><L><L><E><Y><K><S><M><V><D><A><S><E><E><K><T><P><E><Q><I><M><Q><E><K><Q><I><E><A><K><I><E><D><L><E><N><E><I><E><E><V><K><V><A><F><E><I><K><K><L><A><L><D><R><M><R... | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA in... | Q9H3R5 |
A8MYZ6 | FOXO6_HUMAN | Forkhead box protein O6 | Homo | <M><A><A><K><L><R><A><H><Q><V><D><V><D><P><D><F><A><P><Q><S><R><P><R><S><C><T><W><P><L><P><Q><P><D><L><A><G><D><E><D><G><A><L><G><A><G><V><A><E><G><A><E><D><C><G><P><E><R><R><A><T><A><P><A><M><A><P><A><P><P><L><G><A><E><V><G><P><L><R><K><A><K><S><S><R><R><N><A><W><G><N><L><S><Y><A><D><L><I><T><K><A><I><E><S><A><P><D><K... | Transcriptional activator.<BOP> | A8MYZ6 |
Q6RW13 | ATRAP_HUMAN | AT1 receptor-associated protein | Homo | <M><E><L><P><A><V><N><L><K><V><I><L><L><G><H><W><L><L><T><T><W><G><C><I><V><F><S><G><S><Y><A><W><A><N><F><T><I><L><A><L><G><V><W><A><V><A><Q><R><D><S><I><D><A><I><S><M><F><L><G><G><L><L><A><T><I><F><L><D><I><V><H><I><S><I><F><Y><P><R><V><S><L><T><D><T><G><R><F><G><V><G><M><A><I><L><S><L><L><L><K><P><L><S><C><C><F><V><Y... | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.<BOP> | Q6RW13 |
P14927 | QCR7_HUMAN | Ubiquinol-cytochrome c reductase complex 14 kDa protein | Homo | <M><A><G><K><Q><A><V><S><A><S><G><K><W><L><D><G><I><R><K><W><Y><Y><N><A><A><G><F><N><K><L><G><L><M><R><D><D><T><I><Y><E><D><E><D><V><K><E><A><I><R><R><L><P><E><N><L><Y><N><D><R><M><F><R><I><K><R><A><L><D><L><N><L><K><H><Q><I><L><P><K><E><Q><W><T><K><Y><E><E><E><N><F><Y><L><E><P><Y><L><K><E><V><I><R><E><R><K><E><R><E><E... | Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidor... | P14927 |
Q9BWP8 | COL11_HUMAN | Collectin kidney protein 1 | Homo | <M><R><G><N><L><A><L><V><G><V><L><I><S><L><A><F><L><S><L><L><P><S><G><H><P><Q><P><A><G><D><D><A><C><S><V><Q><I><L><V><P><G><L><K><G><D><A><G><E><K><G><D><K><G><A><P><G><R><P><G><R><V><G><P><T><G><E><K><G><D><M><G><D><K><G><Q><K><G><S><V><G><R><H><G><K><I><G><P><I><G><S><K><G><E><K><G><D><S><G><D><I><G><P><P><G><P><N><G... | Lectin that plays a role in innate immunity, apoptosis and embryogenesis . Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope . Primarily recognizes the terminal disaccharide of the glycan . Also recogn... | Q9BWP8 |
Q9Y694 | S22A7_HUMAN | Organic anion transporter 2 | Homo | <M><G><F><E><E><L><L><E><Q><V><G><G><F><G><P><F><Q><L><R><N><V><A><L><L><A><L><P><R><V><L><L><P><L><H><F><L><L><P><I><F><L><A><A><V><P><A><H><R><C><A><L><P><G><A><P><A><N><F><S><H><Q><D><V><W><L><E><A><H><L><P><R><E><P><D><G><T><L><S><S><C><L><R><F><A><Y><P><Q><A><L><P><N><T><T><L><G><E><E><R><Q><S><R><G><E><L><E><D><E... | Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2-alpha, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.<BOP> | Q9Y694 |
Q8WVF2 | UCMA_HUMAN | Gla-rich protein | Homo | <M><T><W><R><Q><A><V><L><L><S><C><F><S><A><V><V><L><L><S><M><L><R><E><G><T><S><V><S><V><G><T><M><Q><M><A><G><E><E><A><S><E><D><A><K><Q><K><I><F><M><Q><E><S><D><A><S><N><F><L><K><R><R><G><K><R><S><P><K><S><R><D><E><V><N><V><E><N><R><Q><K><L><R><V><D><E><L><R><R><E><Y><Y><E><E><Q><R><N><E><F><E><N><F><V><E><E><Q><N><D><E... | May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.<BOP> | Q8WVF2 |
Q9Y6Y0 | NS1BP_HUMAN | Kelch-like protein 39 | Homo | <M><I><P><N><G><Y><L><M><F><E><D><E><N><F><I><E><S><S><V><A><K><L><N><A><L><R><K><S><G><Q><F><C><D><V><R><L><Q><V><C><G><H><E><M><L><A><H><R><A><V><L><A><C><C><S><P><Y><L><F><E><I><F><N><S><D><S><D><P><H><G><I><S><H><V><K><F><D><D><L><N><P><E><A><V><E><V><L><L><N><Y><A><Y><T><A><Q><L><K><A><D><K><E><L><V><K><D><V><Y><S... | (Microbial infection) Involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.<BOP> | Q9Y6Y0 |
Q6UWQ7 | IGFL2_HUMAN | Insulin growth factor-like family member 2 | Homo | <M><V><P><R><I><F><A><P><A><Y><V><S><V><C><L><L><L><L><C><P><R><E><V><I><A><P><A><G><S><E><P><W><L><C><Q><P><A><P><R><C><G><D><K><I><Y><N><P><L><E><Q><C><C><Y><N><D><A><I><V><S><L><S><E><T><R><Q><C><G><P><P><C><T><F><W><P><C><F><E><L><C><C><L><D><S><F><G><L><T><N><D><F><V><V><K><L><K><V><Q><G><V><N><S><Q><C><H><S><S><P... | Potential ligand of the IGFLR1 cell membrane receptor.<BOP> | Q6UWQ7 |
Q9H553 | ALG2_HUMAN | GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase | Homo | <M><A><E><E><Q><G><R><E><R><D><S><V><P><K><P><S><V><L><F><L><H><P><D><L><G><V><G><G><A><E><R><L><V><L><D><A><A><L><A><L><Q><A><R><G><C><S><V><K><I><W><T><A><H><Y><D><P><G><H><C><F><A><E><S><R><E><L><P><V><R><C><A><G><D><W><L><P><R><G><L><G><W><G><G><R><G><A><A><V><C><A><Y><V><R><M><V><F><L><A><L><Y><V><L><F><L><A><D><E... | Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.<BOP> | Q9H553 |
Q14863 | PO6F1_HUMAN | mPOU homeobox protein | Homo | <M><P><G><I><S><S><Q><I><L><T><N><A><Q><G><Q><V><I><G><T><L><P><W><V><V><N><S><A><S><V><A><A><P><A><P><A><Q><S><L><Q><V><Q><A><V><T><P><Q><L><L><L><N><A><Q><G><Q><V><I><A><T><L><A><S><S><P><L><P><P><P><V><A><V><R><K><P><S><T><P><E><S><P><A><K><S><E><V><Q><P><I><Q><P><T><P><T><V><P><Q><P><A><V><V><I><A><S><P><A><P><A><A... | Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').<BOP> | Q14863 |
P54852 | EMP3_HUMAN | Protein YMP | Homo | <M><S><L><L><L><L><V><V><S><A><L><H><I><L><I><L><I><L><L><F><V><A><T><L><D><K><S><W><W><T><L><P><G><K><E><S><L><N><L><W><Y><D><C><T><W><N><N><D><T><K><T><W><A><C><S><N><V><S><E><N><G><W><L><K><A><V><Q><V><L><M><V><L><S><L><I><L><C><C><L><S><F><I><L><F><M><F><Q><L><Y><T><M><R><R><G><G><L><F><Y><A><T><G><L><C><Q><L><C><T... | Probably involved in cell proliferation and cell-cell interactions.<BOP> | P54852 |
Q9NPB8 | GPCP1_HUMAN | Glycerophosphodiester phosphodiesterase 5 | Homo | <M><T><P><S><Q><V><A><F><E><I><R><G><T><L><L><P><G><E><V><F><A><I><C><G><S><C><D><A><L><G><N><W><N><P><Q><N><A><V><A><L><L><P><E><N><D><T><G><E><S><M><L><W><K><A><T><I><V><L><S><R><G><V><S><V><Q><Y><R><Y><F><K><G><Y><F><L><E><P><K><T><I><G><G><P><C><Q><V><I><V><H><K><W><E><T><H><L><Q><P><R><S><I><T><P><L><E><S><E><I><I... | May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity.<BOP> | Q9NPB8 |
Q9Y6H1 | CHCH2_HUMAN | HCV NS2 trans-regulated protein | Homo | <M><P><R><G><S><R><S><R><T><S><R><M><A><P><P><A><S><R><A><P><Q><M><R><A><A><P><R><P><A><P><V><A><Q><P><P><A><A><A><P><P><S><A><V><G><S><S><A><A><A><P><R><Q><P><G><L><M><A><Q><M><A><T><T><A><A><G><V><A><V><G><S><A><V><G><H><T><L><G><H><A><I><T><G><G><F><S><G><G><S><N><A><E><P><A><R><P><D><I><T><Y><Q><E><P><Q><G><T><Q><P... | Transcription factor. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) .<BOP> | Q9Y6H1 |
Q9BW72 | HIG2A_HUMAN | RCF1 homolog B | Homo | <M><A><T><P><G><P><V><I><P><E><V><P><F><E><P><S><K><P><P><V><I><E><G><L><S><P><T><V><Y><R><N><P><E><S><F><K><E><K><F><V><R><K><T><R><E><N><P><V><V><P><I><G><C><L><A><T><A><A><A><L><T><Y><G><L><Y><S><F><H><R><G><N><S><Q><R><S><Q><L><M><M><R><T><R><I><A><A><Q><G><F><T><V><A><A><I><L><L><G><L><A><V><T><A><M><K><S><R><P> | Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes.<BOP> | Q9BW72 |
P0C7T4 | HMSDV_HUMAN | Minor histocompatibility antigen ACC-6 | Homo | <M><E><I><F><I><E><V><F><S><H><F><L><L><Q><L><T><E><L><T><L><N><M><C><L><E><L><P><T><G><S><L><E><K><S><L><M><I><S><S><Q><V><L><Q><I><P><V><A><N><S><T><K><Q><R> | This allelic splice variant of HMSD is the precursor of the histocompatibility antigen ACC-6. More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells. The peptides are derived from polymo... | P0C7T4 |
Q8IUX1 | T126B_HUMAN | Transmembrane protein 126B | Homo | <M><V><V><F><G><Y><E><A><G><T><K><P><R><D><S><G><V><V><P><V><G><T><E><E><A><P><K><V><F><K><M><A><A><S><M><H><G><Q><P><S><P><S><L><E><D><A><K><L><R><R><P><M><V><I><E><I><I><E><K><N><F><D><Y><L><R><K><E><M><T><Q><N><I><Y><Q><M><A><T><F><G><T><T><A><G><F><S><G><I><F><S><N><F><L><F><R><R><C><F><K><V><K><H><D><A><L><K><T><Y... | As part of the MCIA complex, involved in the assembly of the mitochondrial complex I . Participates in constructing the membrane arm of complex I .<BOP> | Q8IUX1 |
O43570 | CAH12_HUMAN | Tumor antigen HOM-RCC-3.1.3 | Homo | <M><P><R><R><S><L><H><A><A><A><V><L><L><L><V><I><L><K><E><Q><P><S><S><P><A><P><V><N><G><S><K><W><T><Y><F><G><P><D><G><E><N><S><W><S><K><K><Y><P><S><C><G><G><L><L><Q><S><P><I><D><L><H><S><D><I><L><Q><Y><D><A><S><L><T><P><L><E><F><Q><G><Y><N><L><S><A><N><K><Q><F><L><L><T><N><N><G><H><S><V><K><L><N><L><P><S><D><M><H><I><Q... | Reversible hydration of carbon dioxide.<BOP> | O43570 |
Q9NUU7 | DD19A_HUMAN | DEAD box protein 19A | Homo | <M><A><T><D><S><W><A><L><A><V><D><E><Q><E><A><A><V><K><S><M><T><N><L><Q><I><K><E><E><K><V><K><A><D><T><N><G><I><I><K><T><S><T><T><A><E><K><T><D><E><E><E><K><E><D><R><A><A><Q><S><L><L><N><K><L><I><R><S><N><L><V><D><N><T><N><Q><V><E><V><L><Q><R><D><P><N><S><P><L><Y><S><V><K><S><F><E><E><L><R><L><K><P><Q><L><L><Q><G><V><Y... | ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.<BOP> | Q9NUU7 |
P16581 | LYAM2_HUMAN | Leukocyte-endothelial cell adhesion molecule 2 | Homo | <M><I><A><S><Q><F><L><S><A><L><T><L><V><L><L><I><K><E><S><G><A><W><S><Y><N><T><S><T><E><A><M><T><Y><D><E><A><S><A><Y><C><Q><Q><R><Y><T><H><L><V><A><I><Q><N><K><E><E><I><E><Y><L><N><S><I><L><S><Y><S><P><S><Y><Y><W><I><G><I><R><K><V><N><N><V><W><V><W><V><G><T><Q><K><P><L><T><E><E><A><K><N><W><A><P><G><E><P><N><N><R><Q><K... | Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.<BOP> | P16581 |
Q9NZH8 | IL36G_HUMAN | Interleukin-1 homolog 1 | Homo | <M><R><G><T><P><G><D><A><D><G><G><G><R><A><V><Y><Q><S><M><C><K><P><I><T><G><T><I><N><D><L><N><Q><Q><V><W><T><L><Q><G><Q><N><L><V><A><V><P><R><S><D><S><V><T><P><V><T><V><A><V><I><T><C><K><Y><P><E><A><L><E><Q><G><R><G><D><P><I><Y><L><G><I><Q><N><P><E><M><C><L><Y><C><E><K><V><G><E><Q><P><T><L><Q><L><K><E><Q><K><I><M><D><L... | Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with w... | Q9NZH8 |
O60499 | STX10_HUMAN | Syntaxin-10 | Homo | <M><S><L><E><D><P><F><F><V><V><R><G><E><V><Q><K><A><V><N><T><A><R><G><L><Y><Q><R><W><C><E><L><L><Q><E><S><A><A><V><G><R><E><E><L><D><W><T><T><N><E><L><R><N><G><L><R><S><I><E><W><D><L><E><D><L><E><E><T><I><G><I><V><E><A><N><P><G><K><F><K><L><P><A><G><D><L><Q><E><R><K><V><F><V><E><R><M><R><E><A><V><Q><E><M><K><D><H><M><V... | SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.<BOP> | O60499 |
Q8NGD5 | OR4KE_HUMAN | Olfactory receptor OR14-22 | Homo | <M><D><P><Q><N><Y><S><L><V><S><E><F><V><L><H><G><L><C><T><S><R><H><L><Q><N><F><F><F><I><F><F><F><G><V><Y><V><A><I><M><L><G><N><L><L><I><L><V><T><V><I><S><D><P><C><L><H><S><S><P><M><Y><F><L><L><G><N><L><A><F><L><D><M><W><L><A><S><F><A><T><P><K><M><I><R><D><F><L><S><D><Q><K><L><I><S><F><G><G><C><M><A><Q><I><F><F><L><H><F... | Odorant receptor.<BOP> | Q8NGD5 |
P35790 | CHKA_HUMAN | Ethanolamine kinase | Homo | <M><K><T><K><F><C><T><G><G><E><A><E><P><S><P><L><G><L><L><L><S><C><G><S><G><S><A><A><P><A><P><G><V><G><Q><Q><R><D><A><A><S><D><L><E><S><K><Q><L><G><G><Q><Q><P><P><L><A><L><P><P><P><P><P><L><P><L><P><L><P><L><P><Q><P><P><P><P><Q><P><P><A><D><E><Q><P><E><P><R><T><R><R><R><A><Y><L><W><C><K><E><F><L><P><G><A><W><R><G><L><R... | This isoform plays a key role in lipolysis of lipid droplets following glucose deprivation . In response to glucose deprivation, phosphorylated by AMPK, promoting localization to lipid droplets . Phosphorylation is followed by acetylation by KAT5, leading to dissociation of the homodimer into a monomer . Monomeric CHKA... | P35790 |
Q96KR6 | F210B_HUMAN | Protein FAM210B, mitochondrial | Homo | <M><A><G><L><L><A><L><L><G><P><A><G><R><V><G><A><R><V><R><P><R><A><T><W><L><L><G><A><T><A><P><C><A><P><P><P><L><A><L><A><L><L><P><P><R><L><D><A><R><L><L><R><T><A><R><G><D><C><R><G><H><Q><D><P><S><Q><A><T><G><T><T><G><S><S><V><S><C><T><E><E><K><K><Q><S><K><S><Q><Q><L><K><K><I><F><Q><E><Y><G><T><V><G><V><S><L><H><I><G><I... | Plays a role in erythroid differentiation . Involved in cell proliferation and tumor cell growth suppression . Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner .<BOP> | Q96KR6 |
Q8NGG6 | OR8BC_HUMAN | Olfactory receptor OR11-317 | Homo | <M><A><A><K><N><S><S><V><T><E><F><I><L><E><G><L><T><H><Q><P><G><L><R><I><P><L><F><F><L><F><L><G><F><Y><T><V><T><V><V><G><N><L><G><L><I><T><L><I><G><L><N><S><H><L><H><T><P><M><Y><F><F><L><F><N><L><S><L><I><D><F><C><F><S><T><T><I><T><P><K><M><L><M><S><F><V><S><R><K><N><I><I><S><F><T><G><C><M><T><Q><L><F><F><F><C><F><F><V... | Odorant receptor.<BOP> | Q8NGG6 |
P21728 | DRD1_HUMAN | Dopamine D1 receptor | Homo | <M><R><T><L><N><T><S><A><M><D><G><T><G><L><V><V><E><R><D><F><S><V><R><I><L><T><A><C><F><L><S><L><L><I><L><S><T><L><L><G><N><T><L><V><C><A><A><V><I><R><F><R><H><L><R><S><K><V><T><N><F><F><V><I><S><L><A><V><S><D><L><L><V><A><V><L><V><M><P><W><K><A><V><A><E><I><A><G><F><W><P><F><G><S><F><C><N><I><W><V><A><F><D><I><M><C><S... | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.<BOP> | P21728 |
Q8N9S9 | SNX31_HUMAN | Sorting nexin-31 | Homo | <M><K><M><H><F><C><I><P><V><S><Q><Q><R><S><D><A><L><G><G><R><Y><V><L><Y><S><V><H><L><D><G><F><L><F><C><R><V><R><Y><S><Q><L><H><G><W><N><E><Q><L><R><R><V><F><G><N><C><L><P><P><F><P><P><K><Y><Y><L><A><M><T><T><A><M><A><D><E><R><R><D><Q><L><E><Q><Y><L><Q><N><V><T><M><D><P><N><V><L><R><S><D><V><F><V><E><F><L><K><L><A><Q><L... | May be involved in protein trafficking.<BOP> | Q8N9S9 |
Q9UHR4 | BI2L1_HUMAN | Insulin receptor tyrosine kinase substrate | Homo | <M><S><R><G><P><E><E><V><N><R><L><T><E><S><T><Y><R><N><V><M><E><Q><F><N><P><G><L><R><N><L><I><N><L><G><K><N><Y><E><K><A><V><N><A><M><I><L><A><G><K><A><Y><Y><D><G><V><A><K><I><G><E><I><A><T><G><S><P><V><S><T><E><L><G><H><V><L><I><E><I><S><S><T><H><K><K><L><N><E><S><L><D><E><N><F><K><K><F><H><K><E><I><I><H><E><L><E><K><K... | May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection.<BOP> | Q9UHR4 |
Q8TAU0 | NKX23_HUMAN | Homeobox protein NK-2 homolog C | Homo | <M><M><L><P><S><P><V><T><S><T><P><F><S><V><K><D><I><L><N><L><E><Q><Q><H><Q><H><F><H><G><A><H><L><Q><A><D><L><E><H><H><F><H><S><A><P><C><M><L><A><A><A><E><G><T><Q><F><S><D><G><G><E><E><D><E><E><D><E><G><E><K><L><S><Y><L><N><S><L><A><A><A><D><G><H><G><D><S><G><L><C><P><Q><G><Y><V><H><T><V><L><R><D><S><C><S><E><P><K><E><H... | Transcription factor.<BOP> | Q8TAU0 |
Q15040 | JOS1_HUMAN | Josephin domain-containing protein 1 | Homo | <M><S><C><V><P><W><K><G><D><K><A><K><S><E><S><L><E><L><P><Q><A><A><P><P><Q><I><Y><H><E><K><Q><R><R><E><L><C><A><L><H><A><L><N><N><V><F><Q><D><S><N><A><F><T><R><D><T><L><Q><E><I><F><Q><R><L><S><P><N><T><M><V><T><P><H><K><K><S><M><L><G><N><G><N><Y><D><V><N><V><I><M><A><A><L><Q><T><K><G><Y><E><A><V><W><W><D><K><R><R><D><V... | Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cel... | Q15040 |
Q969I3 | GLYL1_HUMAN | Glutamine N-acyltransferase | Homo | <M><I><L><L><N><N><S><H><K><L><L><A><L><Y><K><S><L><A><R><S><I><P><E><S><L><K><V><Y><G><S><V><Y><H><I><N><H><G><N><P><F><N><M><E><V><L><V><D><S><W><P><E><Y><Q><M><V><I><I><R><P><Q><K><Q><E><M><T><D><D><M><D><S><Y><T><N><V><Y><R><M><F><S><K><E><P><Q><K><S><E><E><V><L><K><N><C><E><I><V><N><W><K><Q><R><L><Q><I><Q><G><L><Q... | Acyltransferase which transfers an acyl group to the N-terminus of glutamine. Can use phenylacetyl-CoA as an acyl donor.<BOP> | Q969I3 |
P48556 | PSMD8_HUMAN | p31 | Homo | <M><F><I><K><G><R><A><P><R><A><P><P><R><E><R><R><R><A><T><R><G><G><L><R><Q><V><V><A><P><P><R><A><L><G><S><T><S><R><P><H><F><R><R><A><S><V><C><R><R><R><C><R><K><S><G><G><L><L><A><A><S><R><K><M><A><A><A><A><V><N><G><A><A><G><F><S><S><S><G><P><A><A><T><S><G><A><V><L><Q><A><A><T><G><M><Y><E><Q><L><K><G><E><W><N><R><K><S><P... | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions ... | P48556 |
P28358 | HXD10_HUMAN | Homeobox protein Hox-4E | Homo | <M><S><F><P><N><S><S><P><A><A><N><T><F><L><V><D><S><L><I><S><A><C><R><S><D><S><F><Y><S><S><S><A><S><M><Y><M><P><P><P><S><A><D><M><G><T><Y><G><M><Q><T><C><G><L><L><P><S><L><A><K><R><E><V><N><H><Q><N><M><G><M><N><V><H><P><Y><I><P><Q><V><D><S><W><T><D><P><N><R><S><C><R><I><E><Q><P><V><T><Q><Q><V><P><T><C><S><F><T><T><N><I... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P28358 |
Q9Y4A8 | NF2L3_HUMAN | Nuclear factor, erythroid derived 2, like 3 | Homo | <M><K><H><L><K><R><W><W><S><A><G><G><G><L><L><H><L><T><L><L><L><S><L><A><G><L><R><V><D><L><D><L><Y><L><L><L><P><P><P><T><L><L><Q><D><E><L><L><F><L><G><G><P><A><S><S><A><Y><A><L><S><P><F><S><A><S><G><G><W><G><R><A><G><H><L><H><P><K><G><R><E><L><D><P><A><A><P><P><E><G><Q><L><L><R><E><V><R><A><L><G><V><P><F><V><P><R><T><S... | Activates erythroid-specific, globin gene expression.<BOP> | Q9Y4A8 |
O75486 | SUPT3_HUMAN | SPT3-like protein | Homo | <M><N><N><T><A><A><S><P><M><S><T><A><T><S><S><S><G><R><S><T><G><K><S><I><S><F><A><T><E><L><Q><S><M><M><Y><S><L><G><D><A><R><R><P><L><H><E><T><A><V><L><V><E><D><V><V><H><T><Q><L><I><N><L><L><Q><Q><A><A><E><V><S><Q><L><R><G><A><R><V><I><T><P><E><D><L><L><F><L><M><R><K><D><K><K><K><L><R><R><L><L><K><Y><M><F><I><R><D><Y><K... | Probable transcriptional activator.<BOP> | O75486 |
P46663 | BKRB1_HUMAN | B1 bradykinin receptor | Homo | <M><A><S><S><W><P><P><L><E><L><Q><S><S><N><Q><S><Q><L><F><P><Q><N><A><T><A><C><D><N><A><P><E><A><W><D><L><L><H><R><V><L><P><T><F><I><I><S><I><C><F><F><G><L><L><G><N><L><F><V><L><L><V><F><L><L><P><R><R><Q><L><N><V><A><E><I><Y><L><A><N><L><A><A><S><D><L><V><F><V><L><G><L><P><F><W><A><E><N><I><W><N><Q><F><N><W><P><F><G><A... | This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.<BOP> | P46663 |
O00212 | RHOD_HUMAN | Rho-related protein HP1 | Homo | <M><T><A><A><Q><A><A><G><E><E><A><P><P><G><V><R><S><V><K><V><V><L><V><G><D><G><G><C><G><K><T><S><L><L><M><V><F><A><D><G><A><F><P><E><S><Y><T><P><T><V><F><E><R><Y><M><V><N><L><Q><V><K><G><K><P><V><H><L><H><I><W><D><T><A><G><Q><D><D><Y><D><R><L><R><P><L><F><Y><P><D><A><S><V><L><L><L><C><F><D><V><T><S><P><N><S><F><D><N><I... | Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regula... | O00212 |
U3KPV4 | A3LT2_HUMAN | Isoglobotriaosylceramide synthase | Homo | <M><A><L><K><E><G><L><R><A><W><K><R><I><F><W><R><Q><I><L><L><T><L><G><L><L><G><L><F><L><Y><G><L><P><K><F><R><H><L><E><A><L><I><P><M><G><V><C><P><S><A><T><M><S><Q><L><R><D><N><F><T><G><A><L><R><P><W><A><R><P><E><V><L><T><C><T><P><W><G><A><P><I><I><W><D><G><S><F><D><P><D><V><A><K><Q><E><A><R><Q><Q><N><L><T><I><G><L><T><I... | Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactos... | U3KPV4 |
Q8IWE4 | DCNL3_HUMAN | Squamous cell carcinoma-related oncogene 3 | Homo | <M><G><Q><C><V><T><K><C><K><N><P><S><S><T><L><G><S><K><N><G><D><R><E><P><S><N><K><S><H><S><R><R><G><A><G><H><R><E><E><Q><V><P><P><C><G><K><P><G><G><D><I><L><V><N><G><T><K><K><A><E><A><A><T><E><A><C><Q><L><P><T><S><S><G><D><A><G><R><E><S><K><S><N><A><E><E><S><S><L><Q><R><L><E><E><L><F><R><R><Y><K><D><E><R><E><D><A><I><L... | Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage . At the cell membrane, c... | Q8IWE4 |
Q9HAY2 | MAGF1_HUMAN | MAGE-F1 antigen | Homo | <M><L><Q><T><P><E><S><R><G><L><P><V><P><Q><A><E><G><E><K><D><G><G><H><D><G><E><T><R><A><P><T><A><S><Q><E><R><P><K><E><E><L><G><A><G><R><E><E><G><A><A><E><P><A><L><T><R><K><G><A><R><A><L><A><A><K><A><L><A><R><R><R><A><Y><R><R><L><N><R><T><V><A><E><L><V><Q><F><L><L><V><K><D><K><K><K><S><P><I><T><R><S><E><M><V><K><Y><V><I... | Enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin ligases. Proposed to act through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. MAGEF1-NSMCE1 ubiquitin ligase complex promotes proteasomal degradation of MMS19, a key component of t... | Q9HAY2 |
Q9NQZ8 | ZNF71_HUMAN | Zinc finger protein 71 | Homo | <M><K><E><L><D><P><K><N><D><I><S><E><D><K><L><S><V><V><G><E><A><T><G><G><P><T><R><N><G><A><R><G><P><G><S><E><G><V><W><E><P><G><S><W><P><E><R><P><R><G><D><A><G><A><E><W><E><P><L><G><I><P><Q><G><N><K><L><L><G><G><S><V><P><A><C><H><E><L><K><A><F><A><N><Q><G><C><V><L><V><P><P><R><L><D><D><P><T><E><K><G><A><C><P><P><V><R><R... | May be involved in transcriptional regulation.<BOP> | Q9NQZ8 |
P0C628 | O5AC1_HUMAN | Olfactory receptor OR3-2 | Homo | <M><A><E><E><N><K><I><L><V><T><H><F><V><L><T><G><L><T><D><H><P><G><L><Q><A><P><L><F><L><V><F><L><V><I><Y><L><I><T><L><V><G><N><L><G><L><M><A><L><I><W><K><D><P><H><L><H><T><P><I><Y><L><F><L><G><S><L><A><F><A><D><A><C><T><S><S><S><V><T><S><K><M><L><I><N><F><L><S><K><N><H><M><L><S><M><A><K><C><A><T><Q><F><Y><F><F><G><S><N... | Odorant receptor.<BOP> | P0C628 |
Q86YH2 | Z280B_HUMAN | Zinc finger protein 632 | Homo | <M><E><Q><S><C><E><E><E><K><E><P><E><P><Q><K><N><I><Q><E><T><K><Q><V><D><D><E><D><A><E><L><I><F><V><G><V><E><H><V><N><E><D><A><E><L><I><F><V><G><V><T><S><N><S><K><P><V><V><S><N><I><L><N><R><V><T><P><G><S><W><S><R><R><K><K><Y><D><H><L><R><K><D><T><A><R><K><L><Q><P><K><S><H><E><T><V><T><S><E><A><V><T><V><L><P><A><S><Q><L... | May function as a transcription factor.<BOP> | Q86YH2 |
Q02153 | GCYB1_HUMAN | Soluble guanylate cyclase small subunit | Homo | <M><Y><G><F><V><N><H><A><L><E><L><L><V><I><R><N><Y><G><P><E><V><W><E><D><I><K><K><E><A><Q><L><D><E><E><G><Q><F><L><V><R><I><I><Y><D><D><S><K><T><Y><D><L><V><A><A><A><S><K><V><L><N><L><N><A><G><E><I><L><Q><M><F><G><K><M><F><F><V><F><C><Q><E><S><G><Y><D><T><I><L><R><V><L><G><S><N><V><R><E><F><L><Q><N><L><D><A><L><H><D><H... | Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.<BOP> | Q02153 |
Q96SF2 | TCPQM_HUMAN | T-complex protein 1 subunit theta-like 2 | Homo | <M><D><S><T><V><P><S><A><L><E><L><P><Q><R><L><A><L><N><P><R><E><S><P><R><S><P><E><E><E><E><P><H><L><L><S><S><L><A><A><V><Q><T><L><A><S><V><I><R><P><C><Y><G><P><H><G><R><Q><K><F><L><V><T><M><K><G><E><T><V><C><T><G><C><A><T><A><I><L><R><A><L><E><L><E><H><P><A><A><W><L><L><R><E><A><G><Q><T><Q><A><E><N><S><G><D><G><T><A><F... | Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis.<BOP> | Q96SF2 |
Q9UN81 | LORF1_HUMAN | LINE1 retrotransposable element 1 | Homo | <M><G><K><K><Q><N><R><K><T><G><N><S><K><T><Q><S><A><S><P><P><P><K><E><R><S><S><S><P><A><T><E><Q><S><W><M><E><N><D><F><D><E><L><R><E><E><G><F><R><R><S><N><Y><S><E><L><R><E><D><I><Q><T><K><G><K><E><V><E><N><F><E><K><N><L><E><E><C><I><T><R><I><T><N><T><E><K><C><L><K><E><L><M><E><L><K><T><K><A><R><E><L><R><E><E><C><R><S><L... | Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.<BOP> | Q9UN81 |
Q96DE5 | APC16_HUMAN | Cyclosome subunit 16 | Homo | <M><A><A><S><S><S><S><S><S><A><G><G><V><S><G><S><S><V><T><G><S><G><F><S><V><S><D><L><A><P><P><R><K><A><L><F><T><Y><P><K><G><A><G><E><M><L><E><D><G><S><E><R><F><L><C><E><S><V><F><S><Y><Q><V><A><S><T><L><K><Q><V><K><H><D><Q><Q><V><A><R><M><E><K><L><A><G><L><V><E><E><L><E><A><D><E><W><R><F><K><P><I><E><Q><L><L><G><F><T><P... | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'L... | Q96DE5 |
Q12893 | TM115_HUMAN | Protein PL6 | Homo | <M><Q><R><A><L><P><G><A><R><Q><H><L><G><A><I><L><A><S><A><S><V><V><V><K><A><L><C><A><A><V><L><F><L><Y><L><L><S><F><A><V><D><T><G><C><L><A><V><T><P><G><Y><L><F><P><P><N><F><W><I><W><T><L><A><T><H><G><L><M><E><Q><H><V><W><D><V><A><I><S><L><T><T><V><V><V><A><G><R><L><L><E><P><L><W><G><A><L><E><L><L><I><F><F><S><V><V><N><V... | May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.<BOP> | Q12893 |
P30101 | PDIA3_HUMAN | Endoplasmic reticulum resident protein 60 | Homo | <M><R><L><R><R><L><A><L><F><P><G><V><A><L><L><L><A><A><A><R><L><A><A><A><S><D><V><L><E><L><T><D><D><N><F><E><S><R><I><S><D><T><G><S><A><G><L><M><L><V><E><F><F><A><P><W><C><G><H><C><K><R><L><A><P><E><Y><E><A><A><A><T><R><L><K><G><I><V><P><L><A><K><V><D><C><T><A><N><T><N><T><C><N><K><Y><G><V><S><G><Y><P><T><L><K><I><F><R... | Disulfide isomerase which catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds . Associates with calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells . Association with calcitriol does not affect its enzymatic activity .<BOP> | P30101 |
Q13610 | PWP1_HUMAN | Keratinocyte protein IEF SSP 9502 | Homo | <M><N><R><S><R><Q><V><T><C><V><A><W><V><R><C><G><V><A><K><E><T><P><D><K><V><E><L><S><K><E><E><V><K><R><L><I><A><E><A><K><E><K><L><Q><E><E><G><G><G><S><D><E><E><E><T><G><S><P><S><E><D><G><M><Q><S><A><R><T><Q><A><R><P><R><E><P><L><E><D><G><D><P><E><D><D><R><T><L><D><D><D><E><L><A><E><Y><D><L><D><K><Y><D><E><E><G><D><P><D... | Chromatin-associated factor that regulates transcription . Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription . Regulates the epigenetic status of rDNA .<BOP> | Q13610 |
Q8WXH4 | ASB11_HUMAN | Ankyrin repeat and SOCS box protein 11 | Homo | <M><E><D><G><P><V><F><Y><G><F><K><N><I><F><I><T><M><F><A><T><F><F><F><F><K><L><L><I><K><V><F><L><A><L><L><T><H><F><Y><I><V><K><G><N><R><K><E><A><A><R><I><A><E><E><I><Y><G><G><I><S><D><C><W><A><D><R><S><P><L><H><E><A><A><A><Q><G><R><L><L><A><L><K><T><L><I><A><Q><G><V><N><V><N><L><V><T><I><N><R><V><S><S><L><H><E><A><C><L... | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q8WXH4 |
Q58FF6 | H90B4_HUMAN | Putative heat shock protein HSP 90-beta 4 | Homo | <M><S><L><I><I><N><T><F><Y><S><N><K><E><I><F><L><Q><E><L><I><S><N><A><S><D><A><L><D><K><I><R><Y><E><S><L><T><D><P><S><K><L><D><G><G><K><E><L><K><I><D><I><I><P><N><P><R><E><C><I><L><T><L><V><N><T><G><I><G><M><T><K><A><D><L><I><N><N><L><G><A><I><A><K><S><G><T><E><A><F><M><E><A><F><Q><S><C><A><E><I><S><M><I><G><Q><F><G><V... | Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.<BOP> | Q58FF6 |
Q99731 | CCL19_HUMAN | Small-inducible cytokine A19 | Homo | <M><A><L><L><L><A><L><S><L><L><V><L><W><T><S><P><A><P><T><L><S><G><T><N><D><A><E><D><C><C><L><S><V><T><Q><K><P><I><P><G><Y><I><V><R><N><F><H><Y><L><L><I><K><D><G><C><R><V><P><A><V><V><F><T><T><L><R><G><R><Q><L><C><A><P><P><D><Q><P><W><V><E><R><I><I><Q><R><L><Q><R><T><S><A><K><M><K><R><R><S><S> | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chem... | Q99731 |
Q8WV60 | PTCD2_HUMAN | Pentatricopeptide repeat-containing protein 2, mitochondrial | Homo | <M><V><R><D><S><M><A><A><A><F><R><P><S><N><R><V><L><L><Q><A><L><Q><I><L><V><Y><P><G><V><G><G><S><G><S><V><S><C><R><C><P><L><G><A><K><R><Y><L><L><T><D><N><V><V><K><L><K><E><F><Q><Q><K><K><V><A><V><A><C><N><L><S><G><T><K><E><T><Y><F><R><N><L><K><K><K><L><T><Q><N><K><L><I><L><K><G><E><L><I><T><L><L><H><L><C><E><S><R><D><H... | Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.<BOP> | Q8WV60 |
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