accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q9H9V9 | JMJD4_HUMAN | Lysyl-hydroxylase JMJD4 | Homo | <M><R><A><G><P><E><P><Q><A><L><A><G><Q><K><R><G><A><L><R><L><L><V><P><R><L><V><L><T><V><S><A><P><A><E><V><R><R><R><V><L><R><P><V><L><S><W><M><D><R><E><T><R><A><L><A><D><S><H><F><R><G><L><G><V><D><V><P><G><V><G><Q><A><P><G><R><V><A><F><V><S><E><P><G><A><F><S><Y><A><D><F><V><R><G><F><L><L><P><N><L><P><C><V><F><S><S><A><F... | Catalyzes the 2-oxoglutarate and iron-dependent C4-lysyl hydroxylation of ETF1 at 'Lys-63' thereby promoting the translational termination efficiency of ETF1.<BOP> | Q9H9V9 |
O95751 | LDOC1_HUMAN | Leucine zipper protein down-regulated in cancer cells | Homo | <M><V><D><E><L><V><L><L><L><H><A><L><L><M><R><H><R><A><L><S><I><E><N><S><Q><L><M><E><Q><L><R><L><L><V><C><E><R><A><S><L><L><R><Q><V><R><P><P><S><C><P><V><P><F><P><E><T><F><N><G><E><S><S><R><L><P><E><F><I><V><Q><T><A><S><Y><M><L><V><N><E><N><R><F><C><N><D><A><M><K><V><A><F><L><I><S><L><L><T><G><E><A><E><E><W><V><V><P><Y... | May have an important role in the development and/or progression of some cancers.<BOP> | O95751 |
Q96C11 | FGGY_HUMAN | D-ribulokinase FGGY | Homo | <M><S><G><G><E><Q><K><P><E><R><Y><Y><V><G><V><D><V><G><T><G><S><V><R><A><A><L><V><D><Q><S><G><V><L><L><A><F><A><D><Q><P><I><K><N><W><E><P><Q><F><N><H><H><E><Q><S><S><E><D><I><W><A><A><C><C><V><V><T><K><K><V><V><Q><G><I><D><L><N><Q><I><R><G><L><G><F><D><A><T><C><S><L><V><V><L><D><K><Q><F><H><P><L><P><V><N><Q><E><G><D><S... | Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recy... | Q96C11 |
Q9H6S1 | AZI2_HUMAN | TILP | Homo | <M><D><A><L><V><E><D><D><I><C><I><L><N><H><E><K><A><H><K><R><D><T><V><T><P><V><S><I><Y><S><G><D><E><S><V><A><S><H><F><A><L><V><T><A><Y><E><D><I><K><K><R><L><K><D><S><E><K><E><N><S><L><L><K><K><R><I><R><F><L><E><E><K><L><I><A><R><F><E><E><E><T><S><S><V><G><R><E><Q><V><N><K><A><Y><H><A><Y><R><E><V><C><I><D><R><D><N><L><K... | Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity . Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization . Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 . Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-k... | Q9H6S1 |
Q96I25 | SPF45_HUMAN | RNA-binding motif protein 17 | Homo | <M><S><L><Y><D><D><L><G><V><E><T><S><D><S><K><T><E><G><W><S><K><N><F><K><L><L><Q><S><Q><L><Q><V><K><K><A><A><L><T><Q><A><K><S><Q><R><T><K><Q><S><T><V><L><A><P><V><I><D><L><K><R><G><G><S><S><D><D><R><Q><I><V><D><T><P><P><H><V><A><A><G><L><K><D><P><V><P><S><G><F><S><A><G><E><V><L><I><P><L><A><D><E><Y><D><P><M><F><P><N><D... | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in ... | Q96I25 |
O14879 | IFIT3_HUMAN | Retinoic acid-induced gene G protein | Homo | <M><S><E><V><T><K><N><S><L><E><K><I><L><P><Q><L><K><C><H><F><T><W><N><L><F><K><E><D><S><V><S><R><D><L><E><D><R><V><C><N><Q><I><E><F><L><N><T><E><F><K><A><T><M><Y><N><L><L><A><Y><I><K><H><L><D><G><N><N><E><A><A><L><E><C><L><R><Q><A><E><E><L><I><Q><Q><E><H><A><D><Q><A><E><I><R><S><L><V><T><W><G><N><Y><A><W><V><Y><Y><H><L... | IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IR... | O14879 |
Q2TAK8 | PWP3A_HUMAN | Protein expandere | Homo | <M><A><D><A><K><Y><V><L><C><R><W><E><K><R><L><W><P><A><K><V><L><A><R><T><A><T><S><T><K><N><K><R><R><K><E><Y><F><L><A><V><Q><I><L><S><L><E><E><K><I><K><V><K><S><T><E><V><E><I><L><E><K><S><Q><I><E><A><I><A><S><S><L><A><S><Q><N><E><V><P><A><A><P><L><E><E><L><A><Y><R><R><S><L><R><V><A><L><D><V><L><S><E><G><S><I><W><S><Q><E... | Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival ... | Q2TAK8 |
O14832 | PAHX_HUMAN | Phytanoyl-CoA alpha-hydroxylase | Homo | <M><E><Q><L><R><A><A><A><R><L><Q><I><V><L><G><H><L><G><R><P><S><A><G><A><V><V><A><H><P><T><S><G><T><I><S><S><A><S><F><H><P><Q><Q><F><Q><Y><T><L><D><N><N><V><L><T><L><E><Q><R><K><F><Y><E><E><N><G><F><L><V><I><K><N><L><V><P><D><A><D><I><Q><R><F><R><N><E><F><E><K><I><C><R><K><E><V><K><P><L><G><L><T><V><M><R><D><V><T><I><S... | Catalyzes the 2-hydroxylation of not only racemic phytanoyl-CoA and the isomers of 3-methylhexadecanoyl-CoA, but also a variety of other mono-branched 3-methylacyl-CoA esters (with a chain length of at least seven carbon atoms) and straight-chain acyl-CoA esters (with a chain length longer than four carbon atoms) . Doe... | O14832 |
Q96AA3 | RFT1_HUMAN | Protein RFT1 homolog | Homo | <M><G><S><Q><E><V><L><G><H><A><A><R><L><A><S><S><G><L><L><L><Q><V><L><F><R><L><I><T><F><V><L><N><A><F><I><L><R><F><L><S><K><E><I><V><G><V><V><N><V><R><L><T><L><L><Y><S><T><T><L><F><L><A><R><E><A><F><R><R><A><C><L><S><G><G><T><Q><R><D><W><S><Q><T><L><N><L><L><W><L><T><V><P><L><G><V><F><W><S><L><F><L><G><W><I><W><L><Q><L... | May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.<BOP> | Q96AA3 |
Q96N77 | ZN641_HUMAN | Zinc finger protein 641 | Homo | <M><Q><A><E><D><R><S><Q><F><G><S><A><A><E><M><L><S><E><Q><T><A><A><L><G><T><G><W><E><S><M><N><V><Q><L><D><G><A><E><P><Q><V><E><R><G><S><Q><E><E><R><P><W><R><T><V><P><G><P><L><E><H><L><C><C><D><L><E><E><E><P><Q><S><L><Q><E><K><A><Q><S><A><P><W><V><P><A><I><P><Q><E><G><N><T><G><D><W><E><M><A><A><A><L><L><A><A><G><S><Q><G... | Transcriptional activator. Activates transcriptional activities of SRE and AP-1.<BOP> | Q96N77 |
Q8TF45 | ZN418_HUMAN | Zinc finger protein 418 | Homo | <M><Q><G><T><V><A><F><E><D><V><A><V><N><F><S><Q><E><E><W><S><L><L><S><E><V><Q><R><C><L><Y><H><D><V><M><L><E><N><W><V><L><I><S><S><L><G><C><W><C><G><S><E><D><E><E><A><P><S><K><K><S><I><S><I><Q><R><V><S><Q><V><S><T><P><G><A><G><V><S><P><K><K><A><H><S><C><E><M><C><G><A><I><L><G><D><I><L><H><L><A><D><H><Q><G><T><H><H><K><Q... | Transcriptional repressor.<BOP> | Q8TF45 |
Q6FI13 | H2A2A_HUMAN | Histone H2A/o | Homo | <M><S><G><R><G><K><Q><G><G><K><A><R><A><K><A><K><S><R><S><S><R><A><G><L><Q><F><P><V><G><R><V><H><R><L><L><R><K><G><N><Y><A><E><R><V><G><A><G><A><P><V><Y><M><A><A><V><L><E><Y><L><T><A><E><I><L><E><L><A><G><N><A><A><R><D><N><K><K><T><R><I><I><P><R><H><L><Q><L><A><I><R><N><D><E><E><L><N><K><L><L><G><K><V><T><I><A><Q><G><G... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | Q6FI13 |
P01225 | FSHB_HUMAN | Follitropin beta chain | Homo | <M><K><T><L><Q><F><F><F><L><F><C><C><W><K><A><I><C><C><N><S><C><E><L><T><N><I><T><I><A><I><E><K><E><E><C><R><F><C><I><S><I><N><T><T><W><C><A><G><Y><C><Y><T><R><D><L><V><Y><K><D><P><A><R><P><K><I><Q><K><T><C><T><F><K><E><L><V><Y><E><T><V><R><V><P><G><C><A><H><H><A><D><S><L><Y><T><Y><P><V><A><T><Q><C><H><C><G><K><C><D><S... | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways . Follitropin is involved in follicle development and sperm... | P01225 |
P41214 | EIF2D_HUMAN | Ligatin | Homo | <M><F><A><K><A><F><R><V><K><S><N><T><A><I><K><G><S><D><R><R><K><L><R><A><D><V><T><T><A><F><P><T><L><G><T><D><Q><V><S><E><L><V><P><G><K><E><E><L><N><I><V><K><L><Y><A><H><K><G><D><A><V><T><V><Y><V><S><G><G><N><P><I><L><F><E><L><E><K><N><L><Y><P><T><V><Y><T><L><W><S><Y><P><D><L><L><P><T><F><T><T><W><P><L><V><L><E><K><L><V... | Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RN... | P41214 |
Q16790 | CAH9_HUMAN | pMW1 | Homo | <M><A><P><L><C><P><S><P><W><L><P><L><L><I><P><A><P><A><P><G><L><T><V><Q><L><L><L><S><L><L><L><L><V><P><V><H><P><Q><R><L><P><R><M><Q><E><D><S><P><L><G><G><G><S><S><G><E><D><D><P><L><G><E><E><D><L><P><S><E><E><D><S><P><R><E><E><D><P><P><G><E><E><D><L><P><G><E><E><D><L><P><G><E><E><D><L><P><E><V><K><P><K><S><E><E><E><G><S... | Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).<BOP> | Q16790 |
O14682 | ENC1_HUMAN | p53-induced gene 10 protein | Homo | <M><S><V><S><V><H><E><N><R><K><S><R><A><S><S><G><S><I><N><I><Y><L><F><H><K><S><S><Y><A><D><S><V><L><T><H><L><N><L><L><R><Q><Q><R><L><F><T><D><V><L><L><H><A><G><N><R><T><F><P><C><H><R><A><V><L><A><A><C><S><R><Y><F><E><A><M><F><S><G><G><L><K><E><S><Q><D><S><E><V><N><F><D><N><S><I><H><P><E><V><L><E><L><L><L><D><Y><A><Y><S... | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism.<BOP> | O14682 |
Q6UX52 | IL40_HUMAN | Interleukin-40 | Homo | <M><G><L><P><G><L><F><C><L><A><V><L><A><A><S><S><F><S><K><A><R><E><E><E><I><T><P><V><V><S><I><A><Y><K><V><L><E><V><F><P><K><G><R><W><V><L><I><T><C><C><A><P><Q><P><P><P><P><I><T><Y><S><L><C><G><T><K><N><I><K><V><A><K><K><V><V><K><T><H><E><P><A><S><F><N><L><N><V><T><L><K><S><S><P><D><L><L><T><Y><F><C><W><A><S><S><T><S><G... | Probable B cell-associated cytokine that plays a role in the regulation of humoral immune responses. Involved in lymphocyte B cell development and immunoglobulin/IgA production.<BOP> | Q6UX52 |
Q13451 | FKBP5_HUMAN | Rotamase | Homo | <M><T><T><D><E><G><A><K><N><N><E><E><S><P><T><A><T><V><A><E><Q><G><E><D><I><T><S><K><K><D><R><G><V><L><K><I><V><K><R><V><G><N><G><E><E><T><P><M><I><G><D><K><V><Y><V><H><Y><K><G><K><L><S><N><G><K><K><F><D><S><S><H><D><R><N><E><P><F><V><F><S><L><G><K><G><Q><V><I><K><A><W><D><I><G><V><A><T><M><K><K><G><E><I><C><H><L><L><C... | Immunophilin protein with PPIase and co-chaperone activities . Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm ... | Q13451 |
O43687 | AKA7A_HUMAN | Protein kinase A-anchoring protein 7 isoforms alpha/beta | Homo | <M><G><Q><L><C><C><F><P><F><S><R><D><E><G><K><I><S><E><L><E><S><S><S><S><A><V><L><Q><R><Y><S><K><D><I><P><S><W><S><S><G><E><K><N><G><G><E><P><D><D><A><E><L><V><R><L><S><K><R><L><V><E><N><A><V><L><K><A><V><Q><Q><Y><L><E><E><T><Q><N><K><N><K><P><G><E><G><S><S><V><K><T><E><A><A><D><Q><N><G><N><D><N><E><N><N><R><K> | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellul... | O43687 |
O43820 | HYAL3_HUMAN | Lung carcinoma protein 3 | Homo | <M><T><T><Q><L><G><P><A><L><V><L><G><V><A><L><C><L><G><C><G><Q><P><L><P><Q><V><P><E><R><P><F><S><V><L><W><N><V><P><S><A><H><C><E><A><R><F><G><V><H><L><P><L><N><A><L><G><I><I><A><N><R><G><Q><H><F><H><G><Q><N><M><T><I><F><Y><K><N><Q><L><G><L><Y><P><Y><F><G><P><R><G><T><A><H><N><G><G><I><P><Q><A><L><P><L><D><R><H><L><A><L... | Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apopto... | O43820 |
P17844 | DDX5_HUMAN | RNA helicase p68 | Homo | <M><S><G><Y><S><S><D><R><D><R><G><R><D><R><G><F><G><A><P><R><F><G><G><S><R><A><G><P><L><S><G><K><K><F><G><N><P><G><E><K><L><V><K><K><K><W><N><L><D><E><L><P><K><F><E><K><N><F><Y><Q><E><H><P><D><L><A><R><R><T><A><Q><E><V><E><T><Y><R><R><S><K><E><I><T><V><R><G><H><N><C><P><K><P><V><L><N><F><Y><E><A><N><F><P><A><N><V><M><D... | Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA.... | P17844 |
Q9Y6G5 | COMDA_HUMAN | COMM domain-containing protein 10 | Homo | <M><A><V><P><A><A><L><I><L><R><E><S><P><S><M><K><K><A><V><S><L><I><N><A><I><D><T><G><R><F><P><R><L><L><T><R><I><L><Q><K><L><H><L><K><A><E><S><S><F><S><E><E><E><E><E><K><L><Q><A><A><F><S><L><E><K><Q><D><L><H><L><V><L><E><T><I><S><F><I><L><E><Q><A><V><Y><H><N><V><K><P><A><A><L><Q><Q><Q><L><E><N><I><H><L><R><Q><D><K><A><E... | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes . May down-regulate activation of NF-kappa-B .<BOP> | Q9Y6G5 |
Q9Y6I4 | UBP3_HUMAN | Ubiquitin-specific-processing protease 3 | Homo | <M><E><C><P><H><L><S><S><S><V><C><I><A><P><D><S><A><K><F><P><N><G><S><P><S><S><W><C><C><S><V><C><R><S><N><K><S><P><W><V><C><L><T><C><S><S><V><H><C><G><R><Y><V><N><G><H><A><K><K><H><Y><E><D><A><Q><V><P><L><T><N><H><K><K><S><E><K><Q><D><K><V><Q><H><T><V><C><M><D><C><S><S><Y><S><T><Y><C><Y><R><C><D><D><F><V><V><N><D><T><K... | Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.<BOP> | Q9Y6I4 |
Q8TDG2 | ACTT1_HUMAN | Actin-related protein T1 | Homo | <M><F><N><P><H><A><L><D><V><P><A><V><I><F><D><N><G><S><G><L><C><K><A><G><L><S><G><E><I><G><P><R><H><V><I><S><S><V><L><G><H><C><K><F><N><V><P><L><A><R><L><N><Q><K><Y><F><V><G><Q><E><A><L><Y><K><Y><E><A><L><H><L><H><Y><P><I><E><R><G><L><V><T><G><W><D><D><M><E><K><L><W><K><H><L><F><E><R><E><L><G><V><K><P><S><Q><Q><P><V><L... | Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression.<BOP> | Q8TDG2 |
P60827 | C1QT8_HUMAN | C1q/TNF-related protein 8 | Homo | <M><A><A><P><A><L><L><L><L><A><L><L><L><P><V><G><A><W><P><G><L><P><R><R><P><C><V><H><C><C><R><P><A><W><P><P><G><P><Y><A><R><V><S><D><R><D><L><W><R><G><D><L><W><R><G><L><P><R><V><R><P><T><I><D><I><E><I><L><K><G><E><K><G><E><A><G><V><R><G><R><A><G><R><S><G><K><E><G><P><P><G><A><R><G><L><Q><G><R><R><G><Q><K><G><Q><V><G><P... | May play a role as ligand of RXFP1.<BOP> | P60827 |
O95551 | TYDP2_HUMAN | VPg unlinkase | Homo | <M><E><L><G><S><C><L><E><G><G><R><E><A><A><E><E><E><G><E><P><E><V><K><K><R><R><L><L><C><V><E><F><A><S><V><A><S><C><D><A><A><V><A><Q><C><F><L><A><E><N><D><W><E><M><E><R><A><L><N><S><Y><F><E><P><P><V><E><E><S><A><L><E><R><R><P><E><T><I><S><E><P><K><T><Y><V><D><L><T><N><E><E><T><T><D><S><T><T><S><K><I><S><P><S><E><D><T><Q... | (Microbial infection) Also acts as a 5'-tyrosyl-RNA phosphodiesterase following picornavirus infection: its activity is hijacked by picornavirus and acts by specifically cleaving the protein-RNA covalent linkage generated during the viral genomic RNA replication steps of a picornavirus infection, without impairing the ... | O95551 |
O76050 | NEUL1_HUMAN | RING-type E3 ubiquitin transferase NEURL1 | Homo | <M><G><N><N><F><S><S><I><P><S><L><P><R><G><N><P><S><R><A><P><R><G><H><P><Q><N><L><K><D><S><I><G><G><P><F><P><V><T><S><H><R><C><H><H><K><Q><K><H><C><P><A><V><L><P><S><G><G><L><P><A><T><P><L><L><F><H><P><H><T><K><G><S><Q><I><L><M><D><L><S><H><K><A><V><K><R><Q><A><S><F><C><N><A><I><T><F><S><N><R><P><V><L><I><Y><E><Q><V><R... | Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-depend... | O76050 |
A8MTJ6 | FOXI3_HUMAN | Forkhead box protein I3 | Homo | <M><A><L><Y><C><G><D><N><F><G><V><Y><S><Q><P><G><L><P><P><P><A><A><T><A><A><A><P><G><A><P><P><A><A><R><A><P><Y><G><L><A><D><Y><A><A><P><P><A><A><A><A><N><P><Y><L><W><L><N><G><P><G><V><G><G><P><P><S><A><A><A><A><A><A><A><A><Y><L><G><A><P><P><P><P><P><P><P><G><A><A><A><G><P><F><L><Q><P><P><P><A><A><G><T><F><G><C><S><Q><R... | Possible transcriptional factor.<BOP> | A8MTJ6 |
P20813 | CP2B6_HUMAN | Cytochrome P450 IIB1 | Homo | <M><E><L><S><V><L><L><F><L><A><L><L><T><G><L><L><L><L><L><V><Q><R><H><P><N><T><H><D><R><L><P><P><G><P><R><P><L><P><L><L><G><N><L><L><Q><M><D><R><R><G><L><L><K><S><F><L><R><F><R><E><K><Y><G><D><V><F><T><V><H><L><G><P><R><P><V><V><M><L><C><G><V><E><A><I><R><E><A><L><V><D><K><A><E><A><F><S><G><R><G><K><I><A><M><V><D><P><F... | Allele 2B6*9: Has low affinity for anandamide and can only produce 11,12 EpETrE-EAs.<BOP> | P20813 |
Q9UBC0 | HNF6_HUMAN | One cut homeobox 1 | Homo | <M><N><A><Q><L><T><M><E><A><I><G><E><L><H><G><V><S><H><E><P><V><P><A><P><A><D><L><L><G><G><S><P><H><A><R><S><S><V><A><H><R><G><S><H><L><P><P><A><H><P><R><S><M><G><M><A><S><L><L><D><G><G><S><G><G><G><D><Y><H><H><H><H><R><A><P><E><H><S><L><A><G><P><L><H><P><T><M><T><M><A><C><E><T><P><P><G><M><S><M><P><T><T><Y><T><T><L><T... | Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.<BOP> | Q9UBC0 |
O60359 | CCG3_HUMAN | Transmembrane AMPAR regulatory protein gamma-3 | Homo | <M><R><M><C><D><R><G><I><Q><M><L><I><T><T><V><G><A><F><A><A><F><S><L><M><T><I><A><V><G><T><D><Y><W><L><Y><S><R><G><V><C><R><T><K><S><T><S><D><N><E><T><S><R><K><N><E><E><V><M><T><H><S><G><L><W><R><T><C><C><L><E><G><A><F><R><G><V><C><K><K><I><D><H><F><P><E><D><A><D><Y><E><Q><D><T><A><E><Y><L><L><R><A><V><R><A><S><S><V><F... | Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subuni... | O60359 |
Q9Y2T5 | GPR52_HUMAN | G-protein coupled receptor 52 | Homo | <M><N><E><S><R><W><T><E><W><R><I><L><N><M><S><S><G><I><V><N><V><S><E><R><H><S><C><P><L><G><F><G><H><Y><S><V><V><D><V><C><I><F><E><T><V><V><I><V><L><L><T><F><L><I><I><A><G><N><L><T><V><I><F><V><F><H><C><A><P><L><L><H><H><Y><T><T><S><Y><F><I><Q><T><M><A><Y><A><D><L><F><V><G><V><S><C><L><V><P><T><L><S><L><L><H><Y><S><T><G... | Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization . May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine recep... | Q9Y2T5 |
Q8NCD3 | HJURP_HUMAN | Up-regulated in lung cancer 9 | Homo | <M><L><G><T><L><R><A><M><E><G><E><D><V><E><D><D><Q><L><L><Q><K><L><R><A><S><R><R><R><F><Q><R><R><M><Q><R><L><I><E><K><Y><N><Q><P><F><E><D><T><P><V><V><Q><M><A><T><L><T><Y><E><T><P><Q><G><L><R><I><W><G><G><R><L><I><K><E><R><N><E><G><E><I><Q><D><S><S><M><K><P><A><D><R><T><D><G><S><V><Q><A><A><A><W><G><P><E><L><P><S><H><R... | Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerizat... | Q8NCD3 |
Q8N5K1 | CISD2_HUMAN | Nutrient-deprivation autophagy factor-1 | Homo | <M><V><L><E><S><V><A><R><I><V><K><V><Q><L><P><A><Y><L><K><R><L><P><V><P><E><S><I><T><G><F><A><R><L><T><V><S><E><W><L><R><L><L><P><F><L><G><V><L><A><L><L><G><Y><L><A><V><R><P><F><L><P><K><K><K><Q><Q><K><D><S><L><I><N><L><K><I><Q><K><E><N><P><K><V><V><N><E><I><N><I><E><D><L><C><L><T><K><A><A><Y><C><R><C><W><R><S><K><T><F... | Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it ... | Q8N5K1 |
Q9BYR6 | KRA33_HUMAN | Keratin-associated protein 3.3 | Homo | <M><D><C><C><A><S><R><G><C><S><V><P><T><G><P><A><T><T><I><C><S><S><D><K><S><C><R><C><G><V><C><L><P><S><T><C><P><H><T><V><W><L><L><E><P><T><C><C><D><N><C><P><P><P><C><H><I><P><Q><P><C><V><P><T><C><F><L><L><N><S><C><Q><P><T><P><G><L><E><T><L><N><L><T><T><F><T><Q><P><C><C><E><P><C><L><P><R><G><C> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BYR6 |
O95243 | MBD4_HUMAN | Mismatch-specific DNA N-glycosylase | Homo | <M><G><T><T><G><L><E><S><L><S><L><G><D><R><G><A><A><P><T><V><T><S><S><E><R><L><V><P><D><P><P><N><D><L><R><K><E><D><V><A><M><E><L><E><R><V><G><E><D><E><E><Q><M><M><I><K><R><S><S><E><C><N><P><L><L><Q><E><P><I><A><S><A><Q><F><G><A><T><A><G><T><E><C><R><K><S><V><P><C><G><W><E><R><V><V><K><Q><R><L><F><G><K><T><A><G><R><F><D... | Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<BOP> | O95243 |
Q6ZQW0 | I23O2_HUMAN | Indoleamine-pyrrole 2,3-dioxygenase-like protein 1 | Homo | <M><L><H><F><H><Y><Y><D><T><S><N><K><I><M><E><P><H><R><P><N><V><K><T><A><V><P><L><S><L><E><S><Y><H><I><S><E><E><Y><G><F><L><L><P><D><S><L><K><E><L><P><D><H><Y><R><P><W><M><E><I><A><N><K><L><P><Q><L><I><D><A><H><Q><L><Q><A><H><V><D><K><M><P><L><L><S><C><Q><F><L><K><G><H><R><E><Q><R><L><A><H><L><V><L><S><F><L><T><M><G><Y... | Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway . Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance .<BOP> | Q6ZQW0 |
Q7Z4K8 | TRI46_HUMAN | Tripartite, fibronectin type-III and C-terminal SPRY motif protein | Homo | <M><A><E><G><E><D><M><Q><T><F><T><S><I><M><D><A><L><V><R><I><S><T><S><M><K><N><M><E><K><E><L><L><C><P><V><C><Q><E><M><Y><K><Q><P><L><V><L><P><C><T><H><N><V><C><Q><A><C><A><R><E><V><L><G><Q><Q><G><Y><I><G><H><G><G><D><P><S><S><E><P><T><S><P><A><S><T><P><S><T><R><S><P><R><L><S><R><R><T><L><P><K><P><D><R><L><D><R><L><L><K... | Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby al... | Q7Z4K8 |
Q9BY44 | EIF2A_HUMAN | Eukaryotic translation initiation factor 2A, N-terminally processed | Homo | <M><A><P><S><T><P><L><L><T><V><R><G><S><E><G><L><Y><M><V><N><G><P><P><H><F><T><E><S><T><V><F><P><R><E><S><G><K><N><C><K><V><C><I><F><S><K><D><G><T><L><F><A><W><G><N><G><E><K><V><N><I><I><S><V><T><N><K><G><L><L><H><S><F><D><L><L><K><A><V><C><L><E><F><S><P><K><N><T><V><L><A><T><W><Q><P><Y><T><T><S><K><D><G><T><A><G><I><P... | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40... | Q9BY44 |
Q96I15 | SCLY_HUMAN | Selenocysteine lyase | Homo | <M><E><A><A><V><A><P><G><R><D><A><P><A><P><A><A><S><Q><P><S><G><C><G><K><H><N><S><P><E><R><K><V><Y><M><D><Y><N><A><T><T><P><L><E><P><E><V><I><Q><A><M><T><K><A><M><W><E><A><W><G><N><P><S><S><P><Y><S><A><G><R><K><A><K><D><I><I><N><A><A><R><E><S><L><A><K><M><I><G><G><K><P><Q><D><I><I><F><T><S><G><G><T><E><S><N><N><L><V><I... | Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.<BOP> | Q96I15 |
P22083 | FUT4_HUMAN | Galactoside 3-L-fucosyltransferase | Homo | <M><R><R><L><W><G><A><A><R><K><P><S><G><A><G><W><E><K><E><W><A><E><A><P><Q><E><A><P><G><A><W><S><G><R><L><G><P><G><R><S><G><R><K><G><R><A><V><P><G><W><A><S><W><P><A><H><L><A><L><A><A><R><P><A><R><H><L><G><G><A><G><Q><G><P><R><P><L><H><S><G><T><A><P><F><H><S><R><A><S><G><E><R><Q><R><R><L><E><P><Q><L><Q><H><E><S><R><C><R... | Does not generate Lewis X antigens.<BOP> | P22083 |
Q9H8W4 | PKHF2_HUMAN | Zinc finger FYVE domain-containing protein 18 | Homo | <M><V><D><R><L><A><N><S><E><A><N><T><R><R><I><S><I><V><E><N><C><F><G><A><A><G><Q><P><L><T><I><P><G><R><V><L><I><G><E><G><V><L><T><K><L><C><R><K><K><P><K><A><R><Q><F><F><L><F><N><D><I><L><V><Y><G><N><I><V><I><Q><K><K><K><Y><N><K><Q><H><I><I><P><L><E><N><V><T><I><D><S><I><K><D><E><G><D><L><R><N><G><W><L><I><K><T><P><T><K... | May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis .<BOP> | Q9H8W4 |
O14933 | UB2L6_HUMAN | Ubiquitin-protein ligase L6 | Homo | <M><M><A><S><M><R><V><V><K><E><L><E><D><L><Q><K><K><P><P><P><Y><L><R><N><L><S><S><D><D><A><N><V><L><V><W><H><A><L><L><L><P><D><Q><P><P><Y><H><L><K><A><F><N><L><R><I><S><F><P><P><E><Y><P><F><K><P><P><M><I><K><F><T><T><K><I><Y><H><P><N><V><D><E><N><G><Q><I><C><L><P><I><I><S><S><E><N><W><K><P><C><T><K><T><C><Q><V><L><E><A... | Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.<BOP> | O14933 |
O14829 | PPE1_HUMAN | Serine/threonine-protein phosphatase 7 | Homo | <M><G><C><S><S><S><S><T><K><T><R><R><S><D><T><S><L><R><A><A><L><I><I><Q><N><W><Y><R><G><Y><K><A><R><L><K><A><R><Q><H><Y><A><L><T><I><F><Q><S><I><E><Y><A><D><E><Q><G><Q><M><Q><L><S><T><F><F><S><F><M><L><E><N><Y><T><H><I><H><K><E><E><L><E><L><R><N><Q><S><L><E><S><E><Q><D><M><R><D><R><W><D><Y><V><D><S><I><D><V><P><D><S><Y... | May have a role in the recovery or adaptation response of photoreceptors. May have a role in development.<BOP> | O14829 |
A1IGU5 | ARH37_HUMAN | Rho guanine nucleotide exchange factor 37 | Homo | <M><A><K><H><G><A><D><E><P><S><S><R><S><G><S><P><D><R><E><G><R><A><S><E><D><R><S><L><L><H><Q><R><L><A><V><R><E><L><I><D><T><E><V><S><Y><L><H><M><L><Q><L><C><A><S><D><I><R><S><R><L><Q><Q><L><P><Q><G><D><L><D><V><L><F><S><N><I><D><D><I><I><K><V><N><S><R><F><L><H><D><L><Q><E><T><A><S><K><E><E><E><Q><V><Q><L><V><G><N><I><F... | May act as a guanine nucleotide exchange factor (GEF).<BOP> | A1IGU5 |
Q9Y2C5 | S17A4_HUMAN | Solute carrier family 17 member 4 | Homo | <M><S><T><G><P><D><V><K><A><T><V><G><D><I><S><S><D><G><N><L><N><V><A><Q><E><E><C><S><R><K><G><F><C><S><V><R><H><G><L><A><L><I><L><Q><L><C><N><F><S><I><Y><T><Q><Q><M><N><L><S><I><A><I><P><A><M><V><N><N><T><A><P><P><S><Q><P><N><A><S><T><E><R><P><S><T><D><S><Q><G><Y><W><N><E><T><L><K><E><F><K><A><M><A><P><A><Y><D><W><S><P... | Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorgan... | Q9Y2C5 |
A0A075B6I4 | LVX54_HUMAN | Immunoglobulin lambda variable 10-54 | Homo | <M><P><W><A><L><L><L><L><T><L><L><T><H><S><A><V><S><V><V><Q><A><G><L><T><Q><P><P><S><V><S><K><G><L><R><Q><T><A><T><L><T><C><T><G><N><S><N><I><V><G><N><Q><G><A><A><W><L><Q><Q><H><Q><G><H><P><P><K><L><L><S><Y><R><N><N><N><R><P><S><G><I><S><E><R><F><S><A><S><R><S><G><N><T><A><S><L><T><I><T><G><L><Q><P><E><D><E><A><D><Y><Y... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A075B6I4 |
P23193 | TCEA1_HUMAN | Transcription elongation factor TFIIS.o | Homo | <M><E><D><E><V><V><R><F><A><K><K><M><D><K><M><V><Q><K><K><N><A><A><G><A><L><D><L><L><K><E><L><K><N><I><P><M><T><L><E><L><L><Q><S><T><R><I><G><M><S><V><N><A><I><R><K><Q><S><T><D><E><E><V><T><S><L><A><K><S><L><I><K><S><W><K><K><L><L><D><G><P><S><T><E><K><D><L><D><E><K><K><K><E><P><A><I><T><S><Q><N><S><P><E><A><R><E><E><S... | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows ... | P23193 |
Q14626 | I11RA_HUMAN | Soluble interleukin-11 receptor subunit alpha | Homo | <M><S><S><S><C><S><G><L><S><R><V><L><V><A><V><A><T><A><L><V><S><A><S><S><P><C><P><Q><A><W><G><P><P><G><V><Q><Y><G><Q><P><G><R><S><V><K><L><C><C><P><G><V><T><A><G><D><P><V><S><W><F><R><D><G><E><P><K><L><L><Q><G><P><D><S><G><L><G><H><E><L><V><L><A><Q><A><D><S><T><D><E><G><T><Y><I><C><Q><T><L><D><G><A><L><G><G><T><V><T><L... | Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity . The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling .<BOP> | Q14626 |
Q9UM01 | YLAT1_HUMAN | y(+)L-type amino acid transporter 1 | Homo | <M><V><D><S><T><E><Y><E><V><A><S><Q><P><E><V><E><T><S><P><L><G><D><G><A><S><P><G><P><E><Q><V><K><L><K><K><E><I><S><L><L><N><G><V><C><L><I><V><G><N><M><I><G><S><G><I><F><V><S><P><K><G><V><L><I><Y><S><A><S><F><G><L><S><L><V><I><W><A><V><G><G><L><F><S><V><F><G><A><L><C><Y><A><E><L><G><T><T><I><K><K><S><G><A><S><Y><A><Y><I... | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transp... | Q9UM01 |
Q8WY41 | NANO1_HUMAN | EC_Rep1a | Homo | <M><E><A><F><P><W><A><P><R><S><P><R><R><G><R><A><P><P><P><M><A><L><V><P><S><A><R><Y><V><S><A><P><G><P><A><H><P><Q><P><F><S><S><W><N><D><Y><L><G><L><A><T><L><I><T><K><A><V><D><G><E><P><R><F><G><C><A><R><G><G><N><G><G><G><G><S><P><P><S><S><S><S><S><S><C><C><S><P><H><T><G><A><G><P><G><A><L><G><P><A><L><G><P><P><D><Y><D><E... | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion.<B... | Q8WY41 |
Q13765 | NACA_HUMAN | Alpha-NAC | Homo | <M><P><G><E><A><T><E><T><V><P><A><T><E><Q><E><L><P><Q><P><Q><A><E><T><G><S><G><T><E><S><D><S><D><E><S><V><P><E><L><E><E><Q><D><S><T><Q><A><T><T><Q><Q><A><Q><L><A><A><A><A><E><I><D><E><E><P><V><S><K><A><K><Q><S><R><S><E><K><K><A><R><K><A><M><S><K><L><G><L><R><Q><V><T><G><V><T><R><V><T><I><R><K><S><K><N><I><L><F><V><I><T... | Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the in... | Q13765 |
Q5VTQ0 | TT39B_HUMAN | Tetratricopeptide repeat protein 39B | Homo | <M><D><A><V><L><A><C><R><L><R><G><R><G><N><R><V><A><A><L><R><P><R><P><R><P><G><G><S><A><G><P><S><P><F><A><L><L><C><A><G><L><S><P><E><P><R><A><G><V><G><S><E><F><P><A><W><F><L><G><G><S><S><Q><R><R><N><M><A><L><L><G><S><R><A><E><L><E><A><D><E><D><V><F><E><D><A><L><E><T><I><S><I><S><S><H><S><D><M><A><T><S><S><L><H><F><A><S... | Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).<BOP> | Q5VTQ0 |
P20138 | CD33_HUMAN | gp67 | Homo | <M><P><L><L><L><L><L><P><L><L><W><A><G><A><L><A><M><D><P><N><F><W><L><Q><V><Q><E><S><V><T><V><Q><E><G><L><C><V><L><V><P><C><T><F><F><H><P><I><P><Y><Y><D><K><N><S><P><V><H><G><Y><W><F><R><E><G><A><I><I><S><R><D><S><P><V><A><T><N><K><L><D><Q><E><V><Q><E><E><T><Q><G><R><F><R><L><L><G><D><P><S><R><N><N><C><S><L><S><I><V><D... | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state . Preferentially recognizes and binds alpha-2,3- and more avidly alpha-2,6-linked sialic acid-bearing glycans . Upon engagement of ligands such as C1q or syaly... | P20138 |
Q9Y653 | AGRG1_HUMAN | GPR56 subunit beta | Homo | <M><T><P><Q><S><L><L><Q><T><T><L><F><L><L><S><L><L><F><L><V><Q><G><A><H><G><R><G><H><R><E><D><F><R><F><C><S><Q><R><N><Q><T><H><R><S><S><L><H><Y><K><P><T><P><D><L><R><I><S><I><E><N><S><E><E><A><L><T><V><H><A><P><F><P><A><A><H><P><A><S><R><S><F><P><D><P><R><G><L><Y><H><F><C><L><Y><W><N><R><H><A><G><R><L><H><L><L><Y><G><K... | Plays a critical role in cancer progression by activating VEGFA production and angiogenesis through a signaling pathway mediated by PRKCA .<BOP> | Q9Y653 |
Q96M53 | TBATA_HUMAN | Thymus, brain and testes-associated protein | Homo | <M><A><T><D><V><Q><L><A><D><Y><P><L><M><S><P><K><A><E><L><K><L><E><K><K><S><G><R><K><P><R><S><P><R><D><S><G><P><Q><K><E><L><V><I><P><G><I><V><D><F><E><R><I><R><R><A><L><R><T><P><K><P><Q><T><P><G><T><Y><C><F><G><R><L><S><H><H><S><F><F><S><R><H><H><P><H><P><Q><H><V><T><H><I><Q><D><L><T><G><K><P><V><C><V><V><R><D><F><P><A... | May play a role in spermatid differentiation. Modulates thymic stromal cell proliferation and thymus function.<BOP> | Q96M53 |
Q6IPT2 | GAR5A_HUMAN | Golgi-associated RAB2 interactor protein 5A | Homo | <M><G><P><P><L><W><P><D><L><Q><E><P><P><P><P><G><T><S><S><Q><I><R><S><P><L><L><C><D><V><I><K><P><A><P><H><H><D><V><T><V><R><V><V><P><P><P><R><F><L><P><L><L><L><R><P><L><P><S><D><G><D><I><A><M><R><R><D><R><G><P><K><P><A><L><G><G><A><G><E><V><E><P><G><G><M><A><A><S><P><T><G><R><P><R><R><L><Q><R><Y><L><Q><S><G><E><F><D><Q... | RAB2B effector protein which promotes cytosolic DNA-induced innate immune responses. Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis.<BOP> | Q6IPT2 |
Q9H410 | DSN1_HUMAN | Kinetochore-associated protein DSN1 homolog | Homo | <M><T><S><V><T><R><S><E><I><I><D><E><K><G><P><V><M><S><K><T><H><D><H><Q><L><E><S><S><L><S><P><V><E><V><F><A><K><T><S><A><S><L><E><M><N><Q><G><V><S><E><E><R><I><H><L><G><S><S><P><K><K><G><G><N><C><D><L><S><H><Q><E><R><L><Q><S><K><S><L><H><L><S><P><Q><E><Q><S><A><S><Y><Q><D><R><R><Q><S><W><R><R><A><S><M><K><E><T><N><R><R... | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.<BOP> | Q9H410 |
Q13011 | ECH1_HUMAN | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial | Homo | <M><A><A><G><I><V><A><S><R><R><L><R><D><L><L><T><R><R><L><T><G><S><N><Y><P><G><L><S><I><S><L><R><L><T><G><S><S><A><Q><E><E><A><S><G><V><A><L><G><E><A><P><D><H><S><Y><E><S><L><R><V><T><S><A><Q><K><H><V><L><H><V><Q><L><N><R><P><N><K><R><N><A><M><N><K><V><F><W><R><E><M><V><E><C><F><N><K><I><S><R><D><A><D><C><R><A><V><V><I... | Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.<BOP> | Q13011 |
P25101 | EDNRA_HUMAN | Endothelin receptor type A | Homo | <M><E><T><L><C><L><R><A><S><F><W><L><A><L><V><G><C><V><I><S><D><N><P><E><R><Y><S><T><N><L><S><N><H><V><D><D><F><T><T><F><R><G><T><E><L><S><F><L><V><T><T><H><Q><P><T><N><L><V><L><P><S><N><G><S><M><H><N><Y><C><P><Q><Q><T><K><I><T><S><A><F><K><Y><I><N><T><V><I><S><C><T><I><F><I><V><G><M><V><G><N><A><T><L><L><R><I><I><Y><Q... | Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.<BOP> | P25101 |
Q9BTE0 | NAT9_HUMAN | Embryo brain-specific protein | Homo | <M><R><L><N><Q><N><T><L><L><L><G><K><K><V><V><L><V><P><Y><T><S><E><H><V><P><S><R><Y><H><E><W><M><K><S><E><E><L><Q><R><L><T><A><S><E><P><L><T><L><E><Q><E><Y><A><M><Q><C><S><W><Q><E><D><A><D><K><C><T><F><I><V><L><D><A><E><K><W><Q><A><Q><P><G><A><T><E><E><S><C><M><V><G><D><V><N><L><F><L><T><D><L><E><D><L><T><L><G><E><I><E... | N-acetyltransferase that mediates the acetylation of the N-terminal residues of alpha- and beta-tubulin.<BOP> | Q9BTE0 |
Q99676 | ZN184_HUMAN | Zinc finger protein 184 | Homo | <M><E><D><L><S><S><P><D><S><T><L><L><Q><G><G><H><N><L><L><S><S><A><S><F><Q><E><A><V><T><F><K><D><V><I><V><D><F><T><Q><E><E><W><K><Q><L><D><P><G><Q><R><D><L><F><R><D><V><T><L><E><N><Y><T><H><L><V><S><I><G><L><Q><V><S><K><P><D><V><I><S><Q><L><E><Q><G><T><E><P><W><I><M><E><P><S><I><P><V><G><T><C><A><D><W><E><T><R><L><E><N... | May be involved in transcriptional regulation.<BOP> | Q99676 |
P54845 | NRL_HUMAN | Neural retina-specific leucine zipper protein | Homo | <M><A><L><P><P><S><P><L><A><M><E><Y><V><N><D><F><D><L><M><K><F><E><V><K><R><E><P><S><E><G><R><P><G><P><P><T><A><S><L><G><S><T><P><Y><S><S><V><P><P><S><P><T><F><S><E><P><G><M><V><G><A><T><E><G><T><R><P><G><L><E><E><L><Y><W><L><A><T><L><Q><Q><Q><L><G><A><G><E><A><L><G><L><S><P><E><E><A><M><E><L><L><Q><G><Q><G><P><V><P><V... | Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B . Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 . Binds in a sequence-specific manner to the rhodopsin promoter .<BOP> | P54845 |
Q2TAA8 | TXIP1_HUMAN | Translin-associated factor X-interacting protein 1 | Homo | <M><G><G><H><L><S><P><W><P><T><Y><T><S><G><Q><T><I><L><Q><N><R><K><P><C><S><D><D><Y><R><K><R><V><G><S><C><Q><Q><H><P><F><R><T><A><K><P><Q><Y><L><E><E><L><E><N><Y><L><R><K><E><L><L><L><L><D><L><G><T><D><S><T><Q><E><L><R><L><Q><P><Y><R><E><I><F><E><F><F><I><E><D><F><K><T><Y><K><P><L><L><S><S><I><K><N><A><Y><E><G><M><L><A... | Possible role in spermatogenesis.<BOP> | Q2TAA8 |
P55084 | ECHB_HUMAN | Beta-ketothiolase | Homo | <M><T><I><L><T><Y><P><F><K><N><L><P><T><A><S><K><W><A><L><R><F><S><I><R><P><L><S><C><S><S><Q><L><R><A><A><P><A><V><Q><T><K><T><K><K><T><L><A><K><P><N><I><R><N><V><V><V><V><D><G><V><R><T><P><F><L><L><S><G><T><S><Y><K><D><L><M><P><H><D><L><A><R><A><A><L><T><G><L><L><H><R><T><S><V><P><K><E><V><V><D><Y><I><I><F><G><T><V><I... | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway . The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA . Among ... | P55084 |
P21266 | GSTM3_HUMAN | GSTM3-3 | Homo | <M><S><C><E><S><S><M><V><L><G><Y><W><D><I><R><G><L><A><H><A><I><R><L><L><L><E><F><T><D><T><S><Y><E><E><K><R><Y><T><C><G><E><A><P><D><Y><D><R><S><Q><W><L><D><V><K><F><K><L><D><L><D><F><P><N><L><P><Y><L><L><D><G><K><N><K><I><T><Q><S><N><A><I><L><R><Y><I><A><R><K><H><N><M><C><G><E><T><E><E><E><K><I><R><V><D><I><I><E><N><Q... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.<BOP> | P21266 |
Q68D91 | MBLC2_HUMAN | Palmitoyl-coenzyme A thioesterase MBLAC2 | Homo | <M><S><A><L><E><W><Y><A><H><K><S><L><G><D><G><I><F><W><I><Q><E><R><F><Y><E><S><G><N><R><A><N><I><W><L><V><R><G><S><E><Q><D><V><V><I><D><T><G><L><G><L><R><S><L><P><E><Y><L><Y><S><S><G><L><L><Q><D><R><E><A><K><E><D><A><A><R><R><P><L><L><A><V><A><T><H><V><H><F><D><H><S><G><G><L><Y><Q><F><D><R><V><A><V><H><H><A><E><A><E><A... | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH . Has an acyl-CoA thioesterase activity towards the long chain fatty acyl-CoA thioester... | Q68D91 |
P53778 | MK12_HUMAN | Stress-activated protein kinase 3 | Homo | <M><S><S><P><P><P><A><R><S><G><F><Y><R><Q><E><V><T><K><T><A><W><E><V><R><A><V><Y><R><D><L><Q><P><V><G><S><G><A><Y><G><A><V><C><S><A><V><D><G><R><T><G><A><K><V><A><I><K><K><L><Y><R><P><F><Q><S><E><L><F><A><K><R><A><Y><R><E><L><R><L><L><K><H><M><R><H><E><N><V><I><G><L><L><D><V><F><T><P><D><E><T><L><D><D><F><T><D><F><Y><L... | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activ... | P53778 |
Q5SWA1 | PR15B_HUMAN | null | Homo | <M><E><P><G><T><G><G><S><R><K><R><L><G><P><R><A><G><F><R><F><W><P><P><F><F><P><R><R><S><Q><A><G><S><S><K><F><P><T><P><L><G><P><E><N><S><G><N><P><T><L><L><S><S><A><Q><P><E><T><R><V><S><Y><W><T><K><L><L><S><Q><L><L><A><P><L><P><G><L><L><Q><K><V><L><I><W><S><Q><L><F><G><G><M><F><P><T><R><W><L><D><F><A><G><V><Y><S><A><L><R... | Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.<BOP> | Q5SWA1 |
Q12905 | ILF2_HUMAN | Nuclear factor of activated T-cells 45 kDa | Homo | <M><R><G><D><R><G><R><G><R><G><G><R><F><G><S><R><G><G><P><G><G><G><F><R><P><F><V><P><H><I><P><F><D><F><Y><L><C><E><M><A><F><P><R><V><K><P><A><P><D><E><T><S><F><S><E><A><L><L><K><R><N><Q><D><L><A><P><N><S><A><E><Q><A><S><I><L><S><L><V><T><K><I><N><N><V><I><D><N><L><I><V><A><P><G><T><F><E><V><Q><I><E><E><V><R><Q><V><G><S... | (Microbial infection) Plays a positive role in HIV-1 virus production by binding to and thereby stabilizing HIV-1 RNA, together with ILF3.<BOP> | Q12905 |
P43897 | EFTS_HUMAN | Elongation factor Ts, mitochondrial | Homo | <M><S><L><L><R><S><L><R><V><F><L><V><A><R><T><G><S><Y><P><A><G><S><L><L><R><Q><S><P><Q><P><R><H><T><F><Y><A><G><P><R><L><S><A><S><A><S><S><K><E><L><L><M><K><L><R><R><K><T><G><Y><S><F><V><N><C><K><K><A><L><E><T><C><G><G><D><L><K><Q><A><E><I><W><L><H><K><E><A><Q><K><E><G><W><S><K><A><A><K><L><Q><G><R><K><T><K><E><G><L><I... | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP> | P43897 |
O75123 | ZN623_HUMAN | Zinc finger protein 623 | Homo | <M><I><L><L><S><F><V><S><D><S><N><V><G><T><G><E><K><K><V><T><E><A><W><I><S><E><D><E><N><S><H><R><T><T><S><D><R><L><T><V><M><E><L><P><S><P><E><S><E><E><V><H><E><P><R><L><G><E><L><L><G><N><P><E><G><Q><S><L><G><S><S><P><S><Q><D><R><G><C><K><Q><V><T><V><T><H><W><K><I><Q><T><G><E><T><A><Q><V><C><T><K><S><G><R><N><H><I><L><N... | May be involved in transcriptional regulation.<BOP> | O75123 |
Q15620 | OR8B8_HUMAN | Olfactory-like receptor JCG8 | Homo | <M><A><A><E><N><S><S><F><V><T><Q><F><I><L><A><G><L><T><D><Q><P><G><V><Q><I><P><L><F><F><L><F><L><G><F><Y><V><V><T><V><V><G><N><L><G><L><I><T><L><I><R><L><N><S><H><L><H><T><P><M><Y><F><F><L><Y><N><L><S><F><I><D><F><C><Y><S><S><V><I><T><P><K><M><L><M><S><F><V><L><K><K><N><S><I><S><Y><A><G><C><M><T><Q><L><F><F><F><L><F><F... | Odorant receptor (Potential). May be involved in taste perception.<BOP> | Q15620 |
Q9Y231 | FUT9_HUMAN | Galactoside 3-L-fucosyltransferase | Homo | <M><T><S><T><S><K><G><I><L><R><P><F><L><I><V><C><I><I><L><G><C><F><M><A><C><L><L><I><Y><I><K><P><T><N><S><W><I><F><S><P><M><E><S><A><S><S><V><L><K><M><K><N><F><F><S><T><K><T><D><Y><F><N><E><T><T><I><L><V><W><V><W><P><F><G><Q><T><F><D><L><T><S><C><Q><A><M><F><N><I><Q><G><C><H><L><T><T><D><R><S><L><Y><N><K><S><H><A><V><L... | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosy... | Q9Y231 |
Q9NSA1 | FGF21_HUMAN | Fibroblast growth factor 21 | Homo | <M><D><S><D><E><T><G><F><E><H><S><G><L><W><V><S><V><L><A><G><L><L><L><G><A><C><Q><A><H><P><I><P><D><S><S><P><L><L><Q><F><G><G><Q><V><R><Q><R><Y><L><Y><T><D><D><A><Q><Q><T><E><A><H><L><E><I><R><E><D><G><T><V><G><G><A><A><D><Q><S><P><E><S><L><L><Q><L><K><A><L><K><P><G><V><I><Q><I><L><G><V><K><T><S><R><F><L><C><Q><R><P><D... | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.<BOP> | Q9NSA1 |
Q5BJF2 | SGMR2_HUMAN | Transmembrane protein 97 | Homo | <M><G><A><P><A><T><R><R><C><V><E><W><L><L><G><L><Y><F><L><S><H><I><P><I><T><L><F><M><D><L><Q><A><V><L><P><R><E><L><Y><P><V><E><F><R><N><L><L><K><W><Y><A><K><E><F><K><D><P><L><L><Q><E><P><P><A><W><F><K><S><F><L><F><C><E><L><V><F><Q><L><P><F><F><P><I><A><T><Y><A><F><L><K><G><S><C><K><W><I><R><T><P><A><I><I><Y><S><V><H><T... | Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cancer cells . Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation . Under investigation for its potential diagnostic and th... | Q5BJF2 |
A0A0B4J2H0 | HV69D_HUMAN | Immunoglobulin heavy variable 1-69D | Homo | <M><D><W><T><W><R><F><L><F><V><V><A><A><A><T><G><V><Q><S><Q><V><Q><L><V><Q><S><G><A><E><V><K><K><P><G><S><S><V><K><V><S><C><K><A><S><G><G><T><F><S><S><Y><A><I><S><W><V><R><Q><A><P><G><Q><G><L><E><W><M><G><G><I><I><P><I><F><G><T><A><N><Y><A><Q><K><F><Q><G><R><V><T><I><T><A><D><E><S><T><S><T><A><Y><M><E><L><S><S><L><R><S... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0B4J2H0 |
Q99633 | PRP18_HUMAN | PRP18 homolog | Homo | <M><D><I><L><K><S><E><I><L><R><K><R><Q><L><V><E><D><R><N><L><L><V><E><N><K><K><Y><F><K><R><S><E><L><A><K><K><E><E><E><A><Y><F><E><R><C><G><Y><K><I><Q><P><K><E><E><D><Q><K><P><L><T><S><S><N><P><V><L><E><L><E><L><A><E><E><K><L><P><M><T><L><S><R><Q><E><V><I><R><R><L><R><E><R><G><E><P><I><R><L><F><G><E><T><D><Y><D><A><F><Q... | Participates in the second step of pre-mRNA splicing.<BOP> | Q99633 |
Q9H6K1 | ILRUN_HUMAN | Inflammation and lipid regulator with UBA-like and NBR1-like domains protein | Homo | <M><E><G><M><D><V><D><L><D><P><E><L><M><Q><K><F><S><C><L><G><T><T><D><K><D><V><L><I><S><E><F><Q><R><L><L><G><F><Q><L><N><P><A><G><C><A><F><F><L><D><M><T><N><W><N><L><Q><A><A><I><G><A><Y><Y><D><F><E><S><P><N><I><S><V><P><S><M><S><F><V><E><D><V><T><I><G><E><G><E><S><I><P><P><D><T><Q><F><V><K><T><W><R><I><Q><N><S><G><A><E... | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF . Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP .<BOP> | Q9H6K1 |
Q96I76 | GPTC3_HUMAN | G patch domain-containing protein 3 | Homo | <M><A><V><P><G><E><A><E><E><E><A><T><V><Y><L><V><V><S><G><I><P><S><V><L><R><S><A><H><L><R><S><Y><F><S><Q><F><R><E><E><R><G><G><G><F><L><C><F><H><Y><R><H><R><P><E><R><A><P><P><Q><A><A><P><N><S><A><L><I><P><T><D><P><A><A><E><G><Q><L><L><S><Q><T><S><A><T><D><V><R><P><L><S><T><R><D><S><T><P><I><Q><T><R><T><C><C><C><V><I><S... | Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development . Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signa... | Q96I76 |
A0A0B4J238 | TVA12_HUMAN | T cell receptor alpha variable 1-2 | Homo | <M><W><G><V><F><L><L><Y><V><S><M><K><M><G><G><T><T><G><Q><N><I><D><Q><P><T><E><M><T><A><T><E><G><A><I><V><Q><I><N><C><T><Y><Q><T><S><G><F><N><G><L><F><W><Y><Q><Q><H><A><G><E><A><P><T><F><L><S><Y><N><V><L><D><G><L><E><E><K><G><R><F><S><S><F><L><S><R><S><K><G><Y><S><Y><L><L><L><K><E><L><Q><M><K><D><S><A><S><Y><L><C><A> | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A0B4J238 |
Q9Y287 | ITM2B_HUMAN | P23 peptide | Homo | <M><V><K><V><T><F><N><S><A><L><A><Q><K><E><A><K><K><D><E><P><K><S><G><E><E><A><L><I><I><P><P><D><A><V><A><V><D><C><K><D><P><D><D><V><V><P><V><G><Q><R><R><A><W><C><W><C><M><C><F><G><L><A><F><M><L><A><G><V><I><L><G><G><A><Y><L><Y><K><Y><F><A><L><Q><P><D><D><V><Y><Y><C><G><I><K><Y><I><K><D><D><V><I><L><N><E><P><S><A><D><A... | Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.<BOP> | Q9Y287 |
Q93091 | RNAS6_HUMAN | Ribonuclease K6 | Homo | <M><V><L><C><F><P><L><L><L><L><L><L><V><L><W><G><P><V><C><P><L><H><A><W><P><K><R><L><T><K><A><H><W><F><E><I><Q><H><I><Q><P><S><P><L><Q><C><N><R><A><M><S><G><I><N><N><Y><T><Q><H><C><K><H><Q><N><T><F><L><H><D><S><F><Q><N><V><A><A><V><C><D><L><L><S><I><V><C><K><N><R><R><H><N><C><H><Q><S><S><K><P><V><N><M><T><D><C><R><L><T... | Ribonuclease which shows a preference for the pyrimidines uridine and cytosine . Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli . Causes loss of bacterial membrane in... | Q93091 |
Q86YQ2 | LATH_HUMAN | Putative latherin | Homo | <M><L><N><V><S><G><L><F><V><L><L><C><G><L><L><V><S><S><S><A><Q><E><V><L><A><G><V><S><S><Q><L><L><N><D><L><T><Q><G><L><L><R><A><D><F><L><P><S><L><Q><T><T><G><L><Q><K><P><L><S><S><A><F><D><G><V><S><G><L><L><D><I><F><G><P><P><L><T><N><E><I><N><T><V><S><I><Q><V><K><N><P><Q><L><L><H><V><S><I><E><S><T><P><Q><R><K><E><A><T><V... | Major protein in sweat, has surfactant properties.<BOP> | Q86YQ2 |
P29692 | EF1D_HUMAN | Antigen NY-CO-4 | Homo | <M><A><T><N><F><L><A><H><E><K><I><W><F><D><K><F><K><Y><D><D><A><E><R><R><F><Y><E><Q><M><N><G><P><V><A><G><A><S><R><Q><E><N><G><A><S><V><I><L><R><D><I><A><R><A><R><E><N><I><Q><K><S><L><A><G><S><S><G><P><G><A><S><S><G><T><S><G><D><H><G><E><L><V><V><R><I><A><S><L><E><V><E><N><Q><S><L><R><G><V><V><Q><E><L><Q><Q><A><I><S><K... | Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).<BOP> | P29692 |
Q7Z449 | CP2U1_HUMAN | Long-chain fatty acid omega-monooxygenase | Homo | <M><S><S><P><G><P><S><Q><P><P><A><E><D><P><P><W><P><A><R><L><L><R><A><P><L><G><L><L><R><L><D><P><S><G><G><A><L><L><L><C><G><L><V><A><L><L><G><W><S><W><L><R><R><R><R><A><R><G><I><P><P><G><P><T><P><W><P><L><V><G><N><F><G><H><V><L><L><P><P><F><L><R><R><R><S><W><L><S><S><R><T><R><A><A><G><I><D><P><S><V><I><G><P><Q><V><L><L... | A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemopr... | Q7Z449 |
O43193 | MTLR_HUMAN | G-protein coupled receptor 38 | Homo | <M><G><S><P><W><N><G><S><D><G><P><E><G><A><R><E><P><P><W><P><A><L><P><P><C><D><E><R><R><C><S><P><F><P><L><G><A><L><V><P><V><T><A><V><C><L><C><L><F><V><V><G><V><S><G><N><V><V><T><V><M><L><I><G><R><Y><R><D><M><R><T><T><T><N><L><Y><L><G><S><M><A><V><S><D><L><L><I><L><L><G><L><P><F><D><L><Y><R><L><W><R><S><R><P><W><V><F><G... | Receptor for motilin.<BOP> | O43193 |
Q03169 | TNAP2_HUMAN | Primary response gene B94 protein | Homo | <M><S><E><A><S><S><E><D><L><V><P><P><L><E><A><G><A><A><P><Y><R><E><E><E><E><A><A><K><K><K><K><E><K><K><K><K><S><K><G><L><A><N><V><F><C><V><F><T><K><G><K><K><K><K><G><Q><P><S><S><A><E><P><E><D><A><A><G><S><R><Q><G><L><D><G><P><P><P><T><V><E><E><L><K><A><A><L><E><R><G><Q><L><E><A><A><R><P><L><L><A><L><E><R><E><L><A><A><A... | May play a role as a mediator of inflammation and angiogenesis.<BOP> | Q03169 |
P35504 | UD15_HUMAN | UDP-glucuronosyltransferase 1-E | Homo | <M><A><T><G><L><Q><V><P><L><P><Q><L><A><T><G><L><L><L><L><L><S><V><Q><P><W><A><E><S><G><K><V><L><V><V><P><T><D><G><S><H><W><L><S><M><R><E><A><L><R><D><L><H><A><R><G><H><Q><V><V><V><L><T><L><E><V><N><M><Y><I><K><E><E><N><F><F><T><L><T><T><Y><A><I><S><W><T><Q><D><E><F><D><R><L><L><L><G><H><T><Q><S><F><F><E><T><E><H><L><L... | Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.<BOP> | P35504 |
O15266 | SHOX_HUMAN | Short stature homeobox-containing protein | Homo | <M><E><E><L><T><A><F><V><S><K><S><F><D><Q><K><S><K><D><G><N><G><G><G><G><G><G><G><G><K><K><D><S><I><T><Y><R><E><V><L><E><S><G><L><A><R><S><R><E><L><G><T><S><D><S><S><L><Q><D><I><T><E><G><G><G><H><C><P><V><H><L><F><K><D><H><V><D><N><D><K><E><K><L><K><E><F><G><T><A><R><V><A><E><G><I><Y><E><C><K><E><K><R><E><D><V><K><S><E... | Controls fundamental aspects of growth and development.<BOP> | O15266 |
O14931 | NCTR3_HUMAN | Natural killer cell p30-related protein | Homo | <M><A><W><M><L><L><L><I><L><I><M><V><H><P><G><S><C><A><L><W><V><S><Q><P><P><E><I><R><T><L><E><G><S><S><A><F><L><P><C><S><F><N><A><S><Q><G><R><L><A><I><G><S><V><T><W><F><R><D><E><V><V><P><G><K><E><V><R><N><G><T><P><E><F><R><G><R><L><A><P><L><A><S><S><R><F><L><H><D><H><Q><A><E><L><H><I><R><D><V><R><G><H><D><A><S><I><Y><V... | Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also pro... | O14931 |
P42680 | TEC_HUMAN | Tyrosine-protein kinase Tec | Homo | <M><N><F><N><T><I><L><E><E><I><L><I><K><R><S><Q><Q><K><K><K><T><S><P><L><N><Y><K><E><R><L><F><V><L><T><K><S><M><L><T><Y><Y><E><G><R><A><E><K><K><Y><R><K><G><F><I><D><V><S><K><I><K><C><V><E><I><V><K><N><D><D><G><V><I><P><C><Q><N><K><Y><P><F><Q><V><V><H><D><A><N><T><L><Y><I><F><A><P><S><P><Q><S><R><D><L><W><V><K><K><L><K... | Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and dif... | P42680 |
Q8IWL2 | SFTA1_HUMAN | Collectin-4 | Homo | <M><W><L><C><P><L><A><L><N><L><I><L><M><A><A><S><G><A><V><C><E><V><K><D><V><C><V><G><S><P><G><I><P><G><T><P><G><S><H><G><L><P><G><R><D><G><R><D><G><L><K><G><D><P><G><P><P><G><P><M><G><P><P><G><E><M><P><C><P><P><G><N><D><G><L><P><G><A><P><G><I><P><G><E><C><G><E><K><G><E><P><G><E><R><G><P><P><G><L><P><A><H><L><D><E><E><L... | (Microbial infection) Binds M.pneumoniae CARDS toxin, serves as one receptor for this pathogen . When SFTPA1 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen .<BOP> | Q8IWL2 |
Q9HBT8 | Z286A_HUMAN | Zinc finger protein 286A | Homo | <M><E><T><D><L><A><E><M><P><E><K><G><A><L><S><S><Q><D><S><P><H><F><Q><E><K><S><T><E><E><G><E><V><A><A><L><R><L><T><A><R><S><Q><E><T><V><T><F><K><D><V><A><M><D><F><T><P><E><E><W><G><K><L><D><P><A><Q><R><D><V><M><L><E><N><Y><R><N><L><V><S><L><W><L><P><V><S><K><P><E><S><Y><N><L><E><N><G><K><E><P><L><K><L><E><R><K><A><P><K... | May be involved in transcriptional regulation.<BOP> | Q9HBT8 |
Q6UWI2 | PARM1_HUMAN | Prostate androgen-regulated mucin-like protein 1 | Homo | <M><V><Y><K><T><L><F><A><L><C><I><L><T><A><G><W><R><V><Q><S><L><P><T><S><A><P><L><S><V><S><L><P><T><N><I><V><P><P><T><T><I><W><T><S><S><P><Q><N><T><D><A><D><T><A><S><P><S><N><G><T><H><N><N><S><V><L><P><V><T><A><S><A><P><T><S><L><L><P><K><N><I><S><I><E><S><R><E><E><E><I><T><S><P><G><S><N><W><E><G><T><N><T><D><P><S><P><S... | May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis.<BOP> | Q6UWI2 |
Q99436 | PSB7_HUMAN | Proteasome subunit Z | Homo | <M><A><A><V><S><V><Y><A><P><P><V><G><G><F><S><F><D><N><C><R><R><N><A><V><L><E><A><D><F><A><K><R><G><Y><K><L><P><K><V><R><K><T><G><T><T><I><A><G><V><V><Y><K><D><G><I><V><L><G><A><D><T><R><A><T><E><G><M><V><V><A><D><K><N><C><S><K><I><H><F><I><S><P><N><I><Y><C><C><G><A><G><T><A><A><D><T><D><M><T><T><Q><L><I><S><S><N><L><E... | Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participate... | Q99436 |
Q8IYB1 | M21D2_HUMAN | Mab-21 domain-containing protein 2 | Homo | <M><K><M><A><A><P><T><A><N><K><A><A><S><L><G><C><N><N><K><P><A><F><P><E><L><D><F><R><S><G><A><R><V><E><E><L><N><K><L><I><Q><E><F><T><K><H><D><Q><R><E><Y><D><D><Q><R><A><L><E><I><H><T><A><K><D><F><I><F><S><M><L><G><M><V><Q><K><L><D><Q><K><L><P><V><A><N><E><Y><L><L><L><S><G><G><V><R><E><G><V><V><D><L><D><L><D><E><L><N><V... | Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.<BOP> | Q8IYB1 |
Q8N0X7 | SPART_HUMAN | Trans-activated by hepatitis C virus core protein 1 | Homo | <M><E><Q><E><P><Q><N><G><E><P><A><E><I><K><I><I><R><E><A><Y><K><K><A><F><L><F><V><N><K><G><L><N><T><D><E><L><G><Q><K><E><E><A><K><N><Y><Y><K><Q><G><I><G><H><L><L><R><G><I><S><I><S><S><K><E><S><E><H><T><G><P><G><W><E><S><A><R><Q><M><Q><Q><K><M><K><E><T><L><Q><N><V><R><T><R><L><E><I><L><E><K><G><L><A><T><S><L><Q><N><D><L... | May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis .<BOP> | Q8N0X7 |
Q96CA5 | BIRC7_HUMAN | Baculoviral IAP repeat-containing protein 7 30kDa subunit | Homo | <M><G><P><K><D><S><A><K><C><L><H><R><G><P><Q><P><S><H><W><A><A><G><D><G><P><T><Q><E><R><C><G><P><R><S><L><G><S><P><V><L><G><L><D><T><C><R><A><W><D><H><V><D><G><Q><I><L><G><Q><L><R><P><L><T><E><E><E><E><E><E><G><A><G><A><T><L><S><R><G><P><A><F><P><G><M><G><S><E><E><L><R><L><A><S><F><Y><D><W><P><L><T><A><E><V><P><P><E><L... | Blocks etoposide-induced apoptosis . Protects against natural killer (NK) cell-mediated killing .<BOP> | Q96CA5 |
Q92670 | ZN75C_HUMAN | Zinc finger protein 75C pseudogene | Homo | <M><I><M><R><E><L><K><A><D><A><C><L><N><S><H><M><G><A><M><W><E><T><N><R><S><V><K><E><N><S><S><Q><S><K><K><Y><S><T><Q><I><E><C><L><S><P><G><S><A><C><R><H><F><R><S><F><H><Y><H><E><A><T><E><P><L><E><A><I><N><Q><L><Q><K><L><C><H><Q><W><L><R><P><E><I><H><S><K><K><H><I><L><E><M><L><V><L><E><H><F><L><T><I><L><P><K><G><T><Q><N... | May be involved in transcriptional regulation.<BOP> | Q92670 |
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