Datasets:
yangzhang33
/
Prot2Text-Diff-HUMAN-func256-seq768

Dataset card Data Studio Files
xet
Community
1
accession
stringlengths
6
10
name
stringlengths
8
11
Full Name
stringlengths
2
102
⌀
taxon
stringclasses
1 value
sequence
stringlengths
48
2.3k
function
stringlengths
15
1.34k
AlphaFoldDB
stringlengths
6
10
Q96CU9
FXRD1_HUMAN
FAD-dependent oxidoreductase domain-containing protein 1
Homo
<M><I><R><R><V><L><P><H><G><M><G><R><G><L><L><T><R><R><P><G><T><R><R><G><G><F><S><L><D><W><D><G><K><V><S><E><I><K><K><K><I><K><S><I><L><P><G><R><S><C><D><L><L><Q><D><T><S><H><L><P><P><E><H><S><D><V><V><I><V><G><G><G><V><L><G><L><S><V><A><Y><W><L><K><K><L><E><S><R><R><G><A><I><R><V><L><V><V><E><R><D><H><T><Y><S><Q><A><S><T><G><L><S><V><G><G><I><C><Q><Q><F><S><L><P><E><N><I><Q><L><S><L><F><S><A><S><F><L><R><N><I><N><E><Y><L><A><V><V><D><A><P><P><L><D><L><R><F><N><P><S><G><Y><L><L><L><A><S><E><K><D><A><A><A><M><E><S><N><V><K><V><Q><R><Q><E><G><A><K><V><S><L><M><S><P><D><Q><L><R><N><K><F><P><W><I><N><T><E><G><V><A><L><A><S><Y><G><M><E><D><E><G><W><F><D><P><W><C><L><L><Q><G><L><R><R><K><V><Q><S><L><G><V><L><F><C><Q><G><E><V><T><R><F><V><S><S><S><Q><R><M><L><T><T><D><D><K><A><V><V><L><K><R><I><H><E><V><H><V><K><M><D><R><S><L><E><Y><Q><P><V><E><C><A><I><V><I><N><A><A><G><A><W><S><A><Q><I><A><A><L><A><G><V><G><E><G><P><P><G><T><L><Q><G><T><K><L><P><V><E><P><R><K><R><Y><V><Y><V><W><H><C><P><Q><G><P><G><L><E><T><P><L><V><A><D><T><S><G><A><Y><F><R><R><E><G><L><G><S><N><Y><L><G><G><R><S><P><T><E><Q><E><E><P><D><P><A><N><L><E><V><D><H><D><F><F><Q><D><K><V><W><P><H><L><A><L><R><V><P><A><F><E><T><L><K><V><Q><S><A><W><A><G><Y><Y><D><Y><N><T><F><D><Q><N><G><V><V><G><P><H><P><L><V><V><N><M><Y><F><A><T><G><F><S><G><H><G><L><Q><Q><A><P><G><I><G><R><A><V><A><E><M><V><L><K><G><R><F><Q><T><I><D><L><S><P><F><L><F><T><R><F><Y><L><G><E><K><I><Q><E><N><N><I><I>
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) . Involved in mid-late stages of complex I assembly .<BOP>
Q96CU9
P12081
HARS1_HUMAN
Histidyl-tRNA synthetase
Homo
<M><A><E><R><A><A><L><E><E><L><V><K><L><Q><G><E><R><V><R><G><L><K><Q><Q><K><A><S><A><E><L><I><E><E><E><V><A><K><L><L><K><L><K><A><Q><L><G><P><D><E><S><K><Q><K><F><V><L><K><T><P><K><G><T><R><D><Y><S><P><R><Q><M><A><V><R><E><K><V><F><D><V><I><I><R><C><F><K><R><H><G><A><E><V><I><D><T><P><V><F><E><L><K><E><T><L><M><G><K><Y><G><E><D><S><K><L><I><Y><D><L><K><D><Q><G><G><E><L><L><S><L><R><Y><D><L><T><V><P><F><A><R><Y><L><A><M><N><K><L><T><N><I><K><R><Y><H><I><A><K><V><Y><R><R><D><N><P><A><M><T><R><G><R><Y><R><E><F><Y><Q><C><D><F><D><I><A><G><N><F><D><P><M><I><P><D><A><E><C><L><K><I><M><C><E><I><L><S><S><L><Q><I><G><D><F><L><V><K><V><N><D><R><R><I><L><D><G><M><F><A><I><C><G><V><S><D><S><K><F><R><T><I><C><S><S><V><D><K><L><D><K><V><S><W><E><E><V><K><N><E><M><V><G><E><K><G><L><A><P><E><V><A><D><R><I><G><D><Y><V><Q><Q><H><G><G><V><S><L><V><E><Q><L><L><Q><D><P><K><L><S><Q><N><K><Q><A><L><E><G><L><G><D><L><K><L><L><F><E><Y><L><T><L><F><G><I><D><D><K><I><S><F><D><L><S><L><A><R><G><L><D><Y><Y><T><G><V><I><Y><E><A><V><L><L><Q><T><P><A><Q><A><G><E><E><P><L><G><V><G><S><V><A><A><G><G><R><Y><D><G><L><V><G><M><F><D><P><K><G><R><K><V><P><C><V><G><L><S><I><G><V><E><R><I><F><S><I><V><E><Q><R><L><E><A><L><E><E><K><I><R><T><T><E><T><Q><V><L><V><A><S><A><Q><K><K><L><L><E><E><R><L><K><L><V><S><E><L><W><D><A><G><I><K><A><E><L><L><Y><K><K><N><P><K><L><L><N><Q><L><Q><Y><C><E><E><A><G><I><P><L><V><A><I><I><G><E><Q><E><L><K><D><G><V><I><K><L><R><S><V><T><S><R><E><E><V><D><V><R><R><E><D><L><V><E><E><I><K><R><R><T><G><Q><P><L><C><I><C>
Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) . Plays a role in axon guidance .<BOP>
P12081
Q3SY56
SP6_HUMAN
Krueppel-like factor 14
Homo
<M><L><T><A><V><C><G><S><L><G><S><Q><H><T><E><A><P><H><A><S><P><P><R><L><D><L><Q><P><L><Q><T><Y><Q><G><H><T><S><P><E><A><G><D><Y><P><S><P><L><Q><P><G><E><L><Q><S><L><P><L><G><P><E><V><D><F><S><Q><G><Y><E><L><P><G><A><S><S><R><V><T><C><E><D><L><E><S><D><S><P><L><A><P><G><P><F><S><K><L><L><Q><P><D><M><S><H><H><Y><E><S><W><F><R><P><T><H><P><G><A><E><D><G><S><W><W><D><L><H><P><G><T><S><W><M><D><L><P><H><T><Q><G><A><L><T><S><P><G><H><P><G><A><L><Q><A><G><L><G><G><Y><V><G><D><H><Q><L><C><A><P><P><P><H><P><H><A><H><H><L><L><P><A><A><G><G><Q><H><L><L><G><P><P><D><G><A><K><A><L><E><V><A><A><P><E><S><Q><G><L><D><S><S><L><D><G><A><A><R><P><K><G><S><R><R><S><V><P><R><S><S><G><Q><T><V><C><R><C><P><N><C><L><E><A><E><R><L><G><A><P><C><G><P><D><G><G><K><K><K><H><L><H><N><C><H><I><P><G><C><G><K><A><Y><A><K><T><S><H><L><K><A><H><L><R><W><H><S><G><D><R><P><F><V><C><N><W><L><F><C><G><K><R><F><T><R><S><D><E><L><Q><R><H><L><Q><T><H><T><G><T><K><K><F><P><C><A><V><C><S><R><V><F><M><R><S><D><H><L><A><K><H><M><K><T><H><E><G><A><K><E><E><A><A><G><A><A><S><G><E><G><K><A><G><G><A><V><E><P><P><G><G><K><G><K><R><E><A><E><G><S><V><A><P><S><N>
Promotes cell proliferation.<BOP>
Q3SY56
Q92820
GGH_HUMAN
Gamma-Glu-X carboxypeptidase
Homo
<M><A><S><P><G><C><L><L><C><V><L><G><L><L><L><C><G><A><A><S><L><E><L><S><R><P><H><G><D><T><A><K><K><P><I><I><G><I><L><M><Q><K><C><R><N><K><V><M><K><N><Y><G><R><Y><Y><I><A><A><S><Y><V><K><Y><L><E><S><A><G><A><R><V><V><P><V><R><L><D><L><T><E><K><D><Y><E><I><L><F><K><S><I><N><G><I><L><F><P><G><G><S><V><D><L><R><R><S><D><Y><A><K><V><A><K><I><F><Y><N><L><S><I><Q><S><F><D><D><G><D><Y><F><P><V><W><G><T><C><L><G><F><E><E><L><S><L><L><I><S><G><E><C><L><L><T><A><T><D><T><V><D><V><A><M><P><L><N><F><T><G><G><Q><L><H><S><R><M><F><Q><N><F><P><T><E><L><L><L><S><L><A><V><E><P><L><T><A><N><F><H><K><W><S><L><S><V><K><N><F><T><M><N><E><K><L><K><K><F><F><N><V><L><T><T><N><T><D><G><K><I><E><F><I><S><T><M><E><G><Y><K><Y><P><V><Y><G><V><Q><W><H><P><E><K><A><P><Y><E><W><K><N><L><D><G><I><S><H><A><P><N><A><V><K><T><A><F><Y><L><A><E><F><F><V><N><E><A><R><K><N><N><H><H><F><K><S><E><S><E><E><E><K><A><L><I><Y><Q><F><S><P><I><Y><T><G><N><I><S><S><F><Q><Q><C><Y><I><F><D>
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate . May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.<BOP>
Q92820
Q569H4
LARGN_HUMAN
Proline-rich protein 16
Homo
<M><S><A><K><S><K><G><N><P><S><S><S><C><P><A><E><G><P><P><A><A><S><K><T><K><V><K><E><Q><I><K><I><I><V><E><D><L><E><L><V><L><G><D><L><K><D><V><A><K><E><L><K><E><V><V><D><Q><I><D><T><L><T><S><D><L><Q><L><E><D><E><M><T><D><S><S><K><T><D><T><L><N><S><S><S><S><G><T><T><A><S><S><L><E><K><I><K><V><Q><A><N><A><P><L><I><K><P><P><A><H><P><S><A><I><L><T><V><L><R><K><P><N><P><P><P><P><P><P><R><L><T><P><V><K><C><E><D><P><K><R><V><V><P><T><A><N><P><V><K><T><N><G><T><L><L><R><N><G><G><L><P><G><G><P><N><K><I><P><N><G><D><I><C><C><I><P><N><S><N><L><D><K><A><P><V><Q><L><L><M><H><R><P><E><K><D><R><C><P><Q><A><G><P><R><E><R><V><R><F><N><E><K><V><Q><Y><H><G><Y><C><P><D><C><D><T><R><Y><N><I><K><N><R><E><V><H><L><H><S><E><P><V><H><P><P><G><K><I><P><H><Q><G><P><P><L><P><P><T><P><H><L><P><P><F><P><L><E><N><G><G><M><G><I><S><H><S><N><S><F><P><P><I><R><P><A><T><V><P><P><P><T><A><P><K><P><Q><K><T><I><L><R><K><S><T><T><T><T><V>
Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mitochondrial mass and respiration.<BOP>
Q569H4
Q8N302
AGGF1_HUMAN
Vasculogenesis gene on 5q protein
Homo
<M><A><S><E><A><P><S><P><P><R><S><P><P><P><P><T><S><P><E><P><E><L><A><Q><L><R><R><K><V><E><K><L><E><R><E><L><R><S><C><K><R><Q><V><R><E><I><E><K><L><L><H><H><T><E><R><L><Y><Q><N><A><E><S><N><N><Q><E><L><R><T><Q><V><E><E><L><S><K><I><L><Q><R><G><R><N><E><D><N><K><K><S><D><V><E><V><Q><T><E><N><H><A><P><W><S><I><S><D><Y><F><Y><Q><T><Y><Y><N><D><V><S><L><P><N><K><V><T><E><L><S><D><Q><Q><D><Q><A><I><E><T><S><I><L><N><S><K><D><H><L><Q><V><E><N><D><A><Y><P><G><T><D><R><T><E><N><V><K><Y><R><Q><V><D><H><F><A><S><N><S><Q><E><P><A><S><A><L><A><T><E><D><T><S><L><E><G><S><S><L><A><E><S><L><R><A><A><A><E><A><A><V><S><Q><T><G><F><S><Y><D><E><N><T><G><L><Y><F><D><H><S><T><G><F><Y><Y><D><S><E><N><Q><L><Y><Y><D><P><S><T><G><I><Y><Y><Y><C><D><V><E><S><G><R><Y><Q><F><H><S><R><V><D><L><Q><P><Y><P><T><S><S><T><K><Q><S><K><D><K><K><L><K><K><K><R><K><D><P><D><S><S><A><T><N><E><E><K><D><L><N><S><E><D><Q><K><A><F><S><V><E><H><T><S><C><N><E><E><E><N><F><A><N><M><K><K><K><A><K><I><G><I><H><H><K><N><S><P><P><K><V><T><V><P><T><S><G><N><T><I><E><S><P><L><H><E><N><I><S><N><S><T><S><F><K><D><E><K><I><M><E><T><D><S><E><P><E><E><G><E><I><T><D><S><Q><T><E><D><S><Y><D><E><A><I><T><S><E><G><N><V><T><A><E><D><S><E><D><E><D><E><D><K><I><W><P><P><C><I><R><V><I><V><I><R><S><P><V><L><Q><I><G><S><L><F><I><I><T><A><V><N><P><A><T><I><G><R><E><K><D><M><E><H><T><L><R><I><P><E><V><G><V><S><K><F><H><A><E><I><Y><F><D><H><D><L><Q><S><Y><V><L><V><D><Q><G><S><Q><N><G><T><I><V><N><G><K><Q><I><L><Q><P><K><T><K><C><D><P><Y><V><L><E><H><G><D><E><V><K><I><G><E><T><V><L><S><F><H><I><H><P><G><S><D><T><C><D><G><C><E><P><G><Q><V><R><A><H><L><R><L><D><K><K><D><E><S><F><V><G><P><T><L><S><K><E><E><K><E><L><E><R><R><K><E><L><K><K><I><R><V><K><Y><G><L><Q><N><T><E><Y><E><D><E><K><T><L><K><N><P><K><Y><K><D><R><A><G><K><R><R><E><Q><V><G><S><E><G><T><F><Q><R><D><D><A><P><A><S><V><H><S><E><I><T><D><S><N><K><G><R><K><M><L><E><K><M><G><W><K><K><G><E><G><L><G><K><D><G><G><G><M><K><T><P><I><Q><L><Q><L><R><R><T><H><A><G><L><G><T><G><K><P><S><S><F><E><D><V><H><L><L><Q><N><K><N><K><K><N><W><D><K><A><R><E><R><F><T><E><N><F><P><E><T><K><P><Q><K><D><D><P><G><T><M><P><W><V><K><G><T><L><E>
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.<BOP>
Q8N302
P51786
ZN157_HUMAN
Zinc finger protein HZF22
Homo
<M><P><A><N><G><T><S><P><Q><R><F><P><A><L><I><P><G><E><P><G><R><S><F><E><G><S><V><S><F><E><D><V><A><V><D><F><T><R><Q><E><W><H><R><L><D><P><A><Q><R><T><M><H><K><D><V><M><L><E><T><Y><S><N><L><A><S><V><G><L><C><V><A><K><P><E><M><I><F><K><L><E><R><G><E><E><L><W><I><L><E><E><E><S><S><G><H><G><Y><S><G><S><L><S><L><L><C><G><N><G><S><V><G><D><N><A><L><R><H><D><N><D><L><L><H><H><Q><K><I><Q><T><L><D><Q><N><V><E><Y><N><G><C><R><K><A><F><H><E><K><T><G><F><V><R><R><K><R><T><P><R><G><D><K><N><F><E><C><H><E><C><G><K><A><Y><C><R><K><S><N><L><V><E><H><L><R><I><H><T><G><E><R><P><Y><E><C><G><E><C><A><K><T><F><S><A><R><S><Y><L><I><A><H><Q><K><T><H><T><G><E><R><P><F><E><C><N><E><C><G><K><S><F><G><R><K><S><Q><L><I><L><H><T><R><T><H><T><G><E><R><P><Y><E><C><T><E><C><G><K><T><F><S><E><K><A><T><L><T><I><H><Q><R><T><H><T><G><E><K><P><Y><E><C><S><E><C><G><K><T><F><R><V><K><I><S><L><T><Q><H><H><R><T><H><T><G><E><K><P><Y><E><C><G><E><C><G><K><N><F><R><A><K><K><S><L><N><Q><H><Q><R><I><H><T><G><E><K><P><Y><E><C><G><E><C><G><K><F><F><R><M><K><M><T><L><N><N><H><Q><R><T><H><T><G><E><K><P><Y><Q><C><N><E><C><G><K><S><F><R><V><H><S><S><L><G><I><H><Q><R><I><H><T><G><E><K><P><Y><E><C><N><E><C><G><N><A><F><Y><V><K><A><R><L><I><E><H><Q><R><M><H><S><G><E><K><P><Y><E><C><S><E><C><G><K><I><F><S><M><K><K><S><L><C><Q><H><R><R><T><H><T><G><E><K><P><Y><E><C><S><E><C><G><N><A><F><Y><V><K><V><R><L><I><E><H><Q><R><I><H><T><G><E><R><P><F><E><C><Q><E><C><G><K><A><F><C><R><K><A><H><L><T><E><H><Q><R><T><H><I><G><W><S><W><R><C><T><M><K><K><A><S><H>
May be involved in transcriptional regulation.<BOP>
P51786
Q8IXQ5
KLHL7_HUMAN
Kelch-like protein 7
Homo
<M><A><A><S><G><V><E><K><S><S><K><K><K><T><E><K><K><L><A><A><R><E><E><A><K><L><L><A><G><F><M><G><V><M><N><N><M><R><K><Q><K><T><L><C><D><V><I><L><M><V><Q><E><R><K><I><P><A><H><R><V><V><L><A><A><A><S><H><F><F><N><L><M><F><T><T><N><M><L><E><S><K><S><F><E><V><E><L><K><D><A><E><P><D><I><I><E><Q><L><V><E><F><A><Y><T><A><R><I><S><V><N><S><N><N><V><Q><S><L><L><D><A><A><N><Q><Y><Q><I><E><P><V><K><K><M><C><V><D><F><L><K><E><Q><V><D><A><S><N><C><L><G><I><S><V><L><A><E><C><L><D><C><P><E><L><K><A><T><A><D><D><F><I><H><Q><H><F><T><E><V><Y><K><T><D><E><F><L><Q><L><D><V><K><R><V><T><H><L><L><N><Q><D><T><L><T><V><R><A><E><D><Q><V><Y><D><A><A><V><R><W><L><K><Y><D><E><P><N><R><Q><P><F><M><V><D><I><L><A><K><V><R><F><P><L><I><S><K><N><F><L><S><K><T><V><Q><A><E><P><L><I><Q><D><N><P><E><C><L><K><M><V><I><S><G><M><R><Y><H><L><L><S><P><E><D><R><E><E><L><V><D><G><T><R><P><R><R><K><K><H><D><Y><R><I><A><L><F><G><G><S><Q><P><Q><S><C><R><Y><F><N><P><K><D><Y><S><W><T><D><I><R><C><P><F><E><K><R><R><D><A><A><C><V><F><W><D><N><V><V><Y><I><L><G><G><S><Q><L><F><P><I><K><R><M><D><C><Y><N><V><V><K><D><S><W><Y><S><K><L><G><P><P><T><P><R><D><S><L><A><A><C><A><A><E><G><K><I><Y><T><S><G><G><S><E><V><G><N><S><A><L><Y><L><F><E><C><Y><D><T><R><T><E><S><W><H><T><K><P><S><M><L><T><Q><R><C><S><H><G><M><V><E><A><N><G><L><I><Y><V><C><G><G><S><L><G><N><N><V><S><G><R><V><L><N><S><C><E><V><Y><D><P><A><T><E><T><W><T><E><L><C><P><M><I><E><A><R><K><N><H><G><L><V><F><V><K><D><K><I><F><A><V><G><G><Q><N><G><L><G><G><L><D><N><V><E><Y><Y><D><I><K><L><N><E><W><K><M><V><S><P><M><P><W><K><G><V><T><V><K><C><A><A><V><G><S><I><V><Y><V><L><A><G><F><Q><G><V><G><R><L><G><H><I><L><E><Y><N><T><E><T><D><K><W><V><A><N><S><K><V><R><A><F><P><V><T><S><C><L><I><C><V><V><D><T><C><G><A><N><E><E><T><L><E><T>
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.<BOP>
Q8IXQ5
P00739
HPTR_HUMAN
Haptoglobin-related protein
Homo
<M><S><D><L><G><A><V><I><S><L><L><L><W><G><R><Q><L><F><A><L><Y><S><G><N><D><V><T><D><I><S><D><D><R><F><P><K><P><P><E><I><A><N><G><Y><V><E><H><L><F><R><Y><Q><C><K><N><Y><Y><R><L><R><T><E><G><D><G><V><Y><T><L><N><D><K><K><Q><W><I><N><K><A><V><G><D><K><L><P><E><C><E><A><V><C><G><K><P><K><N><P><A><N><P><V><Q><R><I><L><G><G><H><L><D><A><K><G><S><F><P><W><Q><A><K><M><V><S><H><H><N><L><T><T><G><A><T><L><I><N><E><Q><W><L><L><T><T><A><K><N><L><F><L><N><H><S><E><N><A><T><A><K><D><I><A><P><T><L><T><L><Y><V><G><K><K><Q><L><V><E><I><E><K><V><V><L><H><P><N><Y><H><Q><V><D><I><G><L><I><K><L><K><Q><K><V><L><V><N><E><R><V><M><P><I><C><L><P><S><K><N><Y><A><E><V><G><R><V><G><Y><V><S><G><W><G><Q><S><D><N><F><K><L><T><D><H><L><K><Y><V><M><L><P><V><A><D><Q><Y><D><C><I><T><H><Y><E><G><S><T><C><P><K><W><K><A><P><K><S><P><V><G><V><Q><P><I><L><N><E><H><T><F><C><V><G><M><S><K><Y><Q><E><D><T><C><Y><G><D><A><G><S><A><F><A><V><H><D><L><E><E><D><T><W><Y><A><A><G><I><L><S><F><D><K><S><C><A><V><A><E><Y><G><V><Y><V><K><V><T><S><I><Q><H><W><V><Q><K><T><I><A><E><N>
Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.<BOP>
P00739
Q96JC4
ZN479_HUMAN
Zinc finger protein Kr19
Homo
<M><A><K><R><P><G><P><P><G><S><R><E><M><G><L><L><T><F><R><D><I><A><I><E><F><S><L><E><E><W><Q><C><L><D><C><A><Q><R><N><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><S><L><G><I><A><V><S><K><P><D><L><I><T><C><L><E><Q><N><K><E><S><Q><N><I><K><R><N><E><M><V><A><K><H><P><V><T><R><S><H><F><T><Q><D><L><Q><P><E><Q><G><I><K><D><S><L><Q><K><V><I><P><R><T><Y><G><K><C><G><H><E><K><L><Q><F><K><K><C><C><K><S><V><G><E><Y><E><V><H><K><G><G><Y><S><E><V><N><Q><C><L><S><T><T><Q><N><K><I><F><Q><T><H><K><Y><V><K><V><F><G><K><F><S><N><S><N><R><D><K><T><R><Y><T><G><N><K><H><F><K><C><N><K><Y><G><K><S><F><C><M><L><S><H><L><N><Q><H><Q><V><I><H><T><R><E><K><S><Y><K><C><K><E><C><G><K><S><F><N><C><S><S><N><H><T><T><H><K><I><I><H><T><G><E><K><P><Y><R><C><E><E><C><G><K><A><F><S><W><S><A><N><L><T><R><H><K><R><T><H><T><G><E><K><P><Y><T><C><E><E><C><G><Q><A><F><R><R><S><S><A><L><T><N><H><K><R><I><H><T><G><E><R><P><Y><K><C><E><E><C><G><K><A><F><S><V><S><S><T><L><T><D><H><K><R><I><H><T><G><E><K><P><C><R><C><E><E><C><G><K><A><F><S><W><S><S><N><L><T><R><H><K><R><I><H><T><R><E><K><P><Y><A><C><E><E><C><G><Q><A><F><S><L><S><S><N><L><M><R><H><R><R><I><H><T><G><E><K><P><Y><T><C><E><E><C><G><Q><D><F><R><R><S><S><A><L><T><I><H><K><R><I><H><T><G><E><R><P><Y><K><C><E><E><C><G><K><V><F><S><L><S><S><T><L><T><D><H><K><R><I><H><T><G><E><R><P><Y><K><C><E><E><C><G><K><A><F><S><L><S><S><T><L><T><D><H><K><R><I><H><T><G><E><R><P><Y><T><C><E><E><C><G><K><A><F><N><C><S><S><T><L><M><Q><H><K><R><I><H><T><G><E><K><P><Y><K><C><E><E><C><E><Q><A><F><K><W><H><S><S><L><A><K><H><K><I><I><H><T><G><E><K><P><Y><K><C><E>
May be involved in transcriptional regulation.<BOP>
Q96JC4
P30533
AMRP_HUMAN
Low density lipoprotein receptor-related protein-associated protein 1
Homo
<M><A><P><R><R><V><R><S><F><L><R><G><L><P><A><L><L><L><L><L><L><F><L><G><P><W><P><A><A><S><H><G><G><K><Y><S><R><E><K><N><Q><P><K><P><S><P><K><R><E><S><G><E><E><F><R><M><E><K><L><N><Q><L><W><E><K><A><Q><R><L><H><L><P><P><V><R><L><A><E><L><H><A><D><L><K><I><Q><E><R><D><E><L><A><W><K><K><L><K><L><D><G><L><D><E><D><G><E><K><E><A><R><L><I><R><N><L><N><V><I><L><A><K><Y><G><L><D><G><K><K><D><A><R><Q><V><T><S><N><S><L><S><G><T><Q><E><D><G><L><D><D><P><R><L><E><K><L><W><H><K><A><K><T><S><G><K><F><S><G><E><E><L><D><K><L><W><R><E><F><L><H><H><K><E><K><V><H><E><Y><N><V><L><L><E><T><L><S><R><T><E><E><I><H><E><N><V><I><S><P><S><D><L><S><D><I><K><G><S><V><L><H><S><R><H><T><E><L><K><E><K><L><R><S><I><N><Q><G><L><D><R><L><R><R><V><S><H><Q><G><Y><S><T><E><A><E><F><E><E><P><R><V><I><D><L><W><D><L><A><Q><S><A><N><L><T><D><K><E><L><E><A><F><R><E><E><L><K><H><F><E><A><K><I><E><K><H><N><H><Y><Q><K><Q><L><E><I><A><H><E><K><L><R><H><A><E><S><V><G><D><G><E><R><V><S><R><S><R><E><K><H><A><L><L><E><G><R><T><K><E><L><G><Y><T><V><K><K><H><L><Q><D><L><S><G><R><I><S><R><A><R><H><N><E><L>
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.<BOP>
P30533
Q13642
FHL1_HUMAN
Skeletal muscle LIM-protein 1
Homo
<M><A><E><K><F><D><C><H><Y><C><R><D><P><L><Q><G><K><K><Y><V><Q><K><D><G><H><H><C><C><L><K><C><F><D><K><F><C><A><N><T><C><V><E><C><R><K><P><I><G><A><D><S><K><E><V><H><Y><K><N><R><F><W><H><D><T><C><F><R><C><A><K><C><L><H><P><L><A><N><E><T><F><V><A><K><D><N><K><I><L><C><N><K><C><T><T><R><E><D><S><P><K><C><K><G><C><F><K><A><I><V><A><G><D><Q><N><V><E><Y><K><G><T><V><W><H><K><D><C><F><T><C><S><N><C><K><Q><V><I><G><T><G><S><F><F><P><K><G><E><D><F><Y><C><V><T><C><H><E><T><K><F><A><K><H><C><V><K><C><N><K><A><I><T><S><G><G><I><T><Y><Q><D><Q><P><W><H><A><D><C><F><V><C><V><T><C><S><K><K><L><A><G><Q><R><F><T><A><V><E><D><Q><Y><Y><C><V><D><C><Y><K><N><F><V><A><K><K><C><A><G><C><K><N><P><I><T><G><K><R><T><V><S><R><V><S><H><P><V><S><K><A><R><K><P><P><V><C><H><G><K><R><L><P><L><T><L><F><P><S><A><N><L><R><G><R><H><P><G><G><E><R><T><C><P><S><W><V><V><V><L><Y><R><K><N><R><S><L><A><A><P><R><G><P><G><L><V><K><A><P><V><W><W><P><M><K><D><N><P><G><T><T><T><A><S><T><A><K><N><A><P>
May have an involvement in muscle development or hypertrophy.<BOP>
Q13642
Q96EL1
INKA1_HUMAN
Inka box actin regulator 1
Homo
<M><D><M><H><S><A><R><L><D><S><F><L><S><Q><L><R><W><E><L><L><C><G><R><D><T><G><S><P><S><M><P><G><P><L><Q><P><T><S><Q><T><G><P><D><V><Q><P><S><H><Q><L><R><A><S><G><A><L><E><E><D><S><V><C><C><V><E><E><E><E><E><E><E><E><E><A><V><V><T><E><D><R><D><A><A><L><G><G><P><R><E><H><A><L><D><W><D><S><G><F><S><E><V><S><G><S><T><W><R><E><E><E><L><P><V><S><Q><R><P><A><P><S><A><Q><P><L><R><R><Q><C><L><S><V><S><G><L><P><M><P><S><R><A><P><V><A><S><V><P><P><V><H><H><P><R><P><K><S><T><P><D><A><C><L><E><H><W><Q><G><L><E><A><E><D><W><T><A><A><L><L><N><R><G><R><S><R><Q><P><L><V><L><G><D><N><C><F><A><D><L><V><H><N><W><M><E><L><P><E><T><G><S><E><G><G><D><G><G><G><H><R><A><R><A><R><P><P><Q><F><L><L><G><L><S><E><Q><L><R><R><R><L><A><R><A><R><R><T><A><M><A><G><K><R><L><S><C><P><P><R><P><E><P><E><L><P><A><D><V><S><R><F><A><A><L><M><S><C><R><S><R><Q><P><I><I><C><N><D><V><S><Y><L>
Inhibitor of the serine/threonine-protein kinase PAK4 . Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity .<BOP>
Q96EL1
Q9BWW8
APOL6_HUMAN
Apolipoprotein L-VI
Homo
<M><D><N><Q><A><E><R><E><S><E><A><G><V><G><L><Q><R><D><E><D><D><A><P><L><C><E><D><V><E><L><Q><D><G><D><L><S><P><E><E><K><I><F><L><R><E><F><P><R><L><K><E><D><L><K><G><N><I><D><K><L><R><A><L><A><D><D><I><D><K><T><H><K><K><F><T><K><A><N><M><V><A><T><S><T><A><V><I><S><G><V><M><S><L><L><G><L><A><L><A><P><A><T><G><G><G><S><L><L><L><S><T><A><G><Q><G><L><A><T><A><A><G><V><T><S><I><V><S><G><T><L><E><R><S><K><N><K><E><A><Q><A><R><A><E><D><I><L><P><T><Y><D><Q><E><D><R><E><D><E><E><E><K><A><D><Y><V><T><A><A><G><K><I><I><Y><N><L><R><N><T><L><K><Y><A><K><K><N><V><R><A><F><W><K><L><R><A><N><P><R><L><A><N><A><T><K><R><L><L><T><T><G><Q><V><S><S><R><S><R><V><Q><V><Q><K><A><F><A><G><T><T><L><A><M><T><K><N><A><R><V><L><G><G><V><M><S><A><F><S><L><G><Y><D><L><A><T><L><S><K><E><W><K><H><L><K><E><G><A><R><T><K><F><A><E><E><L><R><A><K><A><L><E><L><E><R><K><L><T><E><L><T><Q><L><Y><K><S><L><Q><Q><K><V><R><S><R><A><R><G><V><G><K><D><L><T><G><T><C><E><T><E><A><Y><W><K><E><L><R><E><H><V><W><M><W><L><W><L><C><V><C><L><C><V><C><V><Y><V><Q><F><T>
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.<BOP>
Q9BWW8
Q8NAN2
MIGA1_HUMAN
Protein FAM73A
Homo
<M><S><D><C><C><S><A><P><G><I><S><W><E><A><G><V><G><R><P><A><V><P><G><L><E><L><Q><I><R><R><G><A><M><S><E><E><T><V><S><E><S><Q><F><S><L><K><T><A><A><L><R><V><F><D><L><P><L><T><W><Y><Y><S><L><S><Q><I><K><F><S><P><V><A><K><K><L><F><V><V><T><A><V><S><A><I><S><V><I><F><L><A><H><H><F><K><R><K><R><G><K><K><K><G><K><I><L><P><W><E><P><E><H><L><I><L><E><Y><T><K><R><A><A><S><D><K><G><S><S><C><S><S><S><R><Q><N><L><T><L><S><L><S><S><T><K><D><K><G><S><Q><V><C><N><Y><A><N><G><G><L><F><S><K><Y><S><G><S><A><Q><S><L><A><S><V><Q><S><V><N><S><C><H><S><C><A><C><G><N><S><N><S><W><D><K><A><D><E><D><D><I><K><L><V><N><I><P><V><T><T><P><E><N><L><Y><L><M><G><M><E><L><F><E><E><A><L><R><R><W><E><Q><A><L><T><F><R><N><R><Q><A><E><D><E><A><C><G><S><I><K><L><G><A><G><D><A><I><A><E><E><N><V><D><D><I><I><S><T><E><F><I><H><K><L><E><A><L><L><Q><R><A><Y><R><L><Q><E><E><F><E><A><T><L><G><A><S><D><P><N><S><L><A><D><D><I><D><K><D><T><D><I><T><M><K><G><N><V><E><D><F><G><L><R><D><T><L><S><I><A><S><T><D><S><F><A><S><A><A><E><L><A><E><H><R><E><V><R><H><T><Y><S><L><E><S><L><C><H><C><P><F><Y><E><E><A><M><H><L><V><E><E><G><K><I><Y><S><R><V><L><R><T><E><M><L><E><C><L><G><D><S><D><F><L><A><K><L><H><C><I><R><Q><A><F><Q><V><I><L><S><E><S><A><N><R><I><F><L><A><E><S><G><R><K><I><L><S><A><L><I><V><K><A><R><K><N><P><K><K><F><E><D><V><F><D><E><M><I><Y><F><L><E><Q><T><D><H><W><G><S><T><E><M><E><L><A><A><R><G><V><K><N><L><N><F><Y><D><V><V><L><D><F><I><L><M><D><S><F><E><D><L><E><N><P><P><T><S><I><Q><N><V><V><N><N><R><W><L><N><S><S><F><K><E><T><A><V><A><S><S><C><W><S><V><L><K><Q><K><R><Q><Q><M><K><I><P><D><G><F><F><A><H><F><Y><A><I><C><E><H><I><S><P><V><L><A><W><G><F><L><G><P><R><N><S><L><Y><D><L><C><C><F><F><K><N><Q><V><L><L><F><L><K><D><I><F><D><F><E><K><V><R><Y><S><S><T><E><T><L><A><E><D><L><M><Q><L><L><I><R><R><T><E><L><L><M><A><Y><L><E><A><D><A><L><R><H><T><S><S><C><L><S><S><H><G><H><V><M><S><T><G><L><L><E><A><K><V><Q>
Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD.<BOP>
Q8NAN2
Q9Y6K8
KAD5_HUMAN
ATP-AMP transphosphorylase 5
Homo
<M><N><T><N><D><A><K><E><Y><L><A><R><R><E><I><P><Q><L><F><E><S><L><L><N><G><L><M><C><S><K><P><E><D><P><V><E><Y><L><E><S><C><L><Q><K><V><K><E><L><G><G><C><D><K><V><K><W><D><T><F><V><S><Q><E><K><K><T><L><P><P><L><N><G><G><Q><S><R><R><S><F><L><R><N><V><M><P><E><N><S><N><F><P><Y><R><R><Y><D><R><L><P><P><I><H><Q><F><S><I><E><S><D><T><D><L><S><E><T><A><E><L><I><E><E><Y><E><V><F><D><P><T><R><P><R><P><K><I><I><L><V><I><G><G><P><G><S><G><K><G><T><Q><S><L><K><I><A><E><R><Y><G><F><Q><Y><I><S><V><G><E><L><L><R><K><K><I><H><S><T><S><S><N><R><K><W><S><L><I><A><K><I><I><T><T><G><E><L><A><P><Q><E><T><T><I><T><E><I><K><Q><K><L><M><Q><I><P><D><E><E><G><I><V><I><D><G><F><P><R><D><V><A><Q><A><L><S><F><E><D><Q><I><C><T><P><D><L><V><V><F><L><A><C><A><N><Q><R><L><K><E><R><L><L><K><R><A><E><Q><Q><G><R><P><D><D><N><V><K><A><T><Q><R><R><L><M><N><F><K><Q><N><A><A><P><L><V><K><Y><F><Q><E><K><G><L><I><M><T><F><D><A><D><R><D><E><D><E><V><F><Y><D><I><S><M><A><V><D><N><K><L><F><P><N><K><E><A><A><A><G><S><S><D><L><D><P><S><M><I><L><D><T><G><E><I><I><D><T><G><S><D><Y><E><D><Q><G><D><D><Q><L><N><V><F><G><E><D><T><M><G><G><F><M><E><D><L><R><K><C><K><I><I><F><I><I><G><G><P><G><S><G><K><G><T><Q><C><E><K><L><V><E><K><Y><G><F><T><H><L><S><T><G><E><L><L><R><E><E><L><A><S><E><S><E><R><S><K><L><I><R><D><I><M><E><R><G><D><L><V><P><S><G><I><V><L><E><L><L><K><E><A><M><V><A><S><L><G><D><T><R><G><F><L><I><D><G><Y><P><R><E><V><K><Q><G><E><E><F><G><R><R><I><G><D><P><Q><L><V><I><C><M><D><C><S><A><D><T><M><T><N><R><L><L><Q><R><S><R><S><S><L><P><V><D><D><T><T><K><T><I><A><K><R><L><E><A><Y><Y><R><A><S><I><P><V><I><A><Y><Y><E><T><K><T><Q><L><H><K><I><N><A><E><G><T><P><E><D><V><F><L><Q><L><C><T><A><I><D><S><I><F>
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity.<BOP>
Q9Y6K8
P41161
ETV5_HUMAN
Ets-related protein ERM
Homo
<M><D><G><F><Y><D><Q><Q><V><P><F><M><V><P><G><K><S><R><S><E><E><C><R><G><R><P><V><I><D><R><K><R><K><F><L><D><T><D><L><A><H><D><S><E><E><L><F><Q><D><L><S><Q><L><Q><E><A><W><L><A><E><A><Q><V><P><D><D><E><Q><F><V><P><D><F><Q><S><D><N><L><V><L><H><A><P><P><P><T><K><I><K><R><E><L><H><S><P><S><S><E><L><S><S><C><S><H><E><Q><A><L><G><A><N><Y><G><E><K><C><L><Y><N><Y><C><A><Y><D><R><K><P><P><S><G><F><K><P><L><T><P><P><T><T><P><L><S><P><T><H><Q><N><P><L><F><P><P><P><Q><A><T><L><P><T><S><G><H><A><P><A><A><G><P><V><Q><G><V><G><P><A><P><A><P><H><S><L><P><E><P><G><P><Q><Q><Q><T><F><A><V><P><R><P><P><H><Q><P><L><Q><M><P><K><M><M><P><E><N><Q><Y><P><S><E><Q><R><F><Q><R><Q><L><S><E><P><C><H><P><F><P><P><Q><P><G><V><P><G><D><N><R><P><S><Y><H><R><Q><M><S><E><P><I><V><P><A><A><P><P><P><P><Q><G><F><K><Q><E><Y><H><D><P><L><Y><E><H><G><V><P><G><M><P><G><P><P><A><H><G><F><Q><S><P><M><G><I><K><Q><E><P><R><D><Y><C><V><D><S><E><V><P><N><C><Q><S><S><Y><M><R><G><G><Y><F><S><S><S><H><E><G><F><S><Y><E><K><D><P><R><L><Y><F><D><D><T><C><V><V><P><E><R><L><E><G><K><V><K><Q><E><P><T><M><Y><R><E><G><P><P><Y><Q><R><R><G><S><L><Q><L><W><Q><F><L><V><T><L><L><D><D><P><A><N><A><H><F><I><A><W><T><G><R><G><M><E><F><K><L><I><E><P><E><E><V><A><R><R><W><G><I><Q><K><N><R><P><A><M><N><Y><D><K><L><S><R><S><L><R><Y><Y><Y><E><K><G><I><M><Q><K><V><A><G><E><R><Y><V><Y><K><F><V><C><D><P><D><A><L><F><S><M><A><F><P><D><N><Q><R><P><F><L><K><A><E><S><E><C><H><L><S><E><E><D><T><L><P><L><T><H><F><E><D><S><P><A><Y><L><L><D><M><D><R><C><S><S><L><P><Y><A><E><G><F><A><Y>
Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.<BOP>
P41161
Q96D53
COQ8B_HUMAN
Coenzyme Q protein 8B
Homo
<M><W><L><K><V><G><G><L><L><R><G><T><G><G><Q><L><G><Q><T><V><G><W><P><C><G><A><L><G><P><G><P><H><R><W><G><P><C><G><G><S><W><A><Q><K><F><Y><Q><D><G><P><G><R><G><L><G><E><E><D><I><R><R><A><R><E><A><R><P><R><K><T><P><R><P><Q><L><S><D><R><S><R><E><R><K><V><P><A><S><R><I><S><R><L><A><N><F><G><G><L><A><V><G><L><G><L><G><V><L><A><E><M><A><K><K><S><M><P><G><G><R><L><Q><S><E><G><G><S><G><L><D><S><S><P><F><L><S><E><A><N><A><E><R><I><V><Q><T><L><C><T><V><R><G><A><A><L><K><V><G><Q><M><L><S><I><Q><D><N><S><F><I><S><P><Q><L><Q><H><I><F><E><R><V><R><Q><S><A><D><F><M><P><R><W><Q><M><L><R><V><L><E><E><E><L><G><R><D><W><Q><A><K><V><A><S><L><E><E><V><P><F><A><A><A><S><I><G><Q><V><H><Q><G><L><L><R><D><G><T><E><V><A><V><K><I><Q><Y><P><G><I><A><Q><S><I><Q><S><D><V><Q><N><L><L><A><V><L><K><M><S><A><A><L><P><A><G><L><F><A><E><Q><S><L><Q><A><L><Q><Q><E><L><A><W><E><C><D><Y><R><R><E><A><A><C><A><Q><N><F><R><Q><L><L><A><N><D><P><F><F><R><V><P><A><V><V><K><E><L><C><T><T><R><V><L><G><M><E><L><A><G><G><V><P><L><D><Q><C><Q><G><L><S><Q><D><L><R><N><Q><I><C><F><Q><L><L><T><L><C><L><R><E><L><F><E><F><R><F><M><Q><T><D><P><N><W><A><N><F><L><Y><D><A><S><S><H><Q><V><T><L><L><D><F><G><A><S><R><E><F><G><T><E><F><T><D><H><Y><I><E><V><V><K><A><A><A><D><G><D><R><D><C><V><L><Q><K><S><R><D><L><K><F><L><T><G><F><E><T><K><A><F><S><D><A><H><V><E><A><V><M><I><L><G><E><P><F><A><T><Q><G><P><Y><D><F><G><S><G><E><T><A><R><R><I><Q><D><L><I><P><V><L><L><R><H><R><L><C><P><P><P><E><E><T><Y><A><L><H><R><K><L><A><G><A><F><L><A><C><A><H><L><R><A><H><I><A><C><R><D><L><F><Q><D><T><Y><H><R><Y><W><A><S><R><Q><P><D><A><A><T><A><G><S><L><P><T><K><G><D><S><W><V><D><P><S>
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration . Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration .<BOP>
Q96D53
Q6P1J9
CDC73_HUMAN
Hyperparathyroidism 2 protein
Homo
<M><A><D><V><L><S><V><L><R><Q><Y><N><I><Q><K><K><E><I><V><V><K><G><D><E><V><I><F><G><E><F><S><W><P><K><N><V><K><T><N><Y><V><V><W><G><T><G><K><E><G><Q><P><R><E><Y><Y><T><L><D><S><I><L><F><L><L><N><N><V><H><L><S><H><P><V><Y><V><R><R><A><A><T><E><N><I><P><V><V><R><R><P><D><R><K><D><L><L><G><Y><L><N><G><E><A><S><T><S><A><S><I><D><R><S><A><P><L><E><I><G><L><Q><R><S><T><Q><V><K><R><A><A><D><E><V><L><A><E><A><K><K><P><R><I><E><D><E><E><C><V><R><L><D><K><E><R><L><A><A><R><L><E><G><H><K><E><G><I><V><Q><T><E><Q><I><R><S><L><S><E><A><M><S><V><E><K><I><A><A><I><K><A><K><I><M><A><K><K><R><S><T><I><K><T><D><L><D><D><D><I><T><A><L><K><Q><R><S><F><V><D><A><E><V><D><V><T><R><D><I><V><S><R><E><R><V><W><R><T><R><T><T><I><L><Q><S><T><G><K><N><F><S><K><N><I><F><A><I><L><Q><S><V><K><A><R><E><E><G><R><A><P><E><Q><R><P><A><P><N><A><A><P><V><D><P><T><L><R><T><K><Q><P><I><P><A><A><Y><N><R><Y><D><Q><E><R><F><K><G><K><E><E><T><E><G><F><K><I><D><T><M><G><T><Y><H><G><M><T><L><K><S><V><T><E><G><A><S><A><R><K><T><Q><T><P><A><A><Q><P><V><P><R><P><V><S><Q><A><R><P><P><P><N><Q><K><K><G><S><R><T><P><I><I><I><I><P><A><A><T><T><S><L><I><T><M><L><N><A><K><D><L><L><Q><D><L><K><F><V><P><S><D><E><K><K><K><Q><G><C><Q><R><E><N><E><T><L><I><Q><R><R><K><D><Q><M><Q><P><G><G><T><A><I><S><V><T><V><P><Y><R><V><V><D><Q><P><L><K><L><M><P><Q><D><W><D><R><V><V><A><V><F><V><Q><G><P><A><W><Q><F><K><G><W><P><W><L><L><P><D><G><S><P><V><D><I><F><A><K><I><K><A><F><H><L><K><Y><D><E><V><R><L><D><P><N><V><Q><K><W><D><V><T><V><L><E><L><S><Y><H><K><R><H><L><D><R><P><V><F><L><R><F><W><E><T><L><D><R><Y><M><V><K><H><K><S><H><L><R><F>
Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL
Q6P1J9
O00115
DNS2A_HUMAN
R31240_2
Homo
<M><I><P><L><L><L><A><A><L><L><C><V><P><A><G><A><L><T><C><Y><G><D><S><G><Q><P><V><D><W><F><V><V><Y><K><L><P><A><L><R><G><S><G><E><A><A><Q><R><G><L><Q><Y><K><Y><L><D><E><S><S><G><G><W><R><D><G><R><A><L><I><N><S><P><E><G><A><V><G><R><S><L><Q><P><L><Y><R><S><N><T><S><Q><L><A><F><L><L><Y><N><D><Q><P><P><Q><P><S><K><A><Q><D><S><S><M><R><G><H><T><K><G><V><L><L><L><D><H><D><G><G><F><W><L><V><H><S><V><P><N><F><P><P><P><A><S><S><A><A><Y><S><W><P><H><S><A><C><T><Y><G><Q><T><L><L><C><V><S><F><P><F><A><Q><F><S><K><M><G><K><Q><L><T><Y><T><Y><P><W><V><Y><N><Y><Q><L><E><G><I><F><A><Q><E><F><P><D><L><E><N><V><V><K><G><H><H><V><S><Q><E><P><W><N><S><S><I><T><L><T><S><Q><A><G><A><V><F><Q><S><F><A><K><F><S><K><F><G><D><D><L><Y><S><G><W><L><A><A><A><L><G><T><N><L><Q><V><Q><F><W><H><K><T><V><G><I><L><P><S><N><C><S><D><I><W><Q><V><L><N><V><N><Q><I><A><F><P><G><P><A><G><P><S><F><N><S><T><E><D><H><S><K><W><C><V><S><P><K><G><P><W><T><C><V><G><D><M><N><R><N><Q><G><E><E><Q><R><G><G><G><T><L><C><A><Q><L><P><A><L><W><K><A><F><Q><P><L><V><K><N><Y><Q><P><C><N><G><M><A><R><K><P><S><R><A><Y><K><I>
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.<BOP>
O00115
Q15599
NHRF2_HUMAN
Tyrosine kinase activator protein 1
Homo
<M><A><A><P><E><P><L><R><P><R><L><C><R><L><V><R><G><E><Q><G><Y><G><F><H><L><H><G><E><K><G><R><R><G><Q><F><I><R><R><V><E><P><G><S><P><A><E><A><A><A><L><R><A><G><D><R><L><V><E><V><N><G><V><N><V><E><G><E><T><H><H><Q><V><V><Q><R><I><K><A><V><E><G><Q><T><R><L><L><V><V><D><Q><E><T><D><E><E><L><R><R><R><Q><L><T><C><T><E><E><M><A><Q><R><G><L><P><P><A><H><D><P><W><E><P><K><P><D><W><A><H><T><G><S><H><S><S><E><A><G><K><K><D><V><S><G><P><L><R><E><L><R><P><R><L><C><H><L><R><K><G><P><Q><G><Y><G><F><N><L><H><S><D><K><S><R><P><G><Q><Y><I><R><S><V><D><P><G><S><P><A><A><R><S><G><L><R><A><Q><D><R><L><I><E><V><N><G><Q><N><V><E><G><L><R><H><A><E><V><V><A><S><I><K><A><R><E><D><E><A><R><L><L><V><V><D><P><E><T><D><E><H><F><K><R><L><R><V><T><P><T><E><E><H><V><E><G><P><L><P><S><P><V><T><N><G><T><S><P><A><Q><L><N><G><G><S><A><C><S><S><R><S><D><L><P><G><S><D><K><D><T><E><D><G><S><A><W><K><Q><D><P><F><Q><E><S><G><L><H><L><S><P><T><A><A><E><A><K><E><K><A><R><A><M><R><V><N><K><R><A><P><Q><M><D><W><N><R><K><R><E><I><F><S><N><F>
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 . May also act as scaffold protein in the nucleus.<BOP>
Q15599
O76075
DFFB_HUMAN
DNA fragmentation factor 40 kDa subunit
Homo
<M><L><Q><K><P><K><S><V><K><L><R><A><L><R><S><P><R><K><F><G><V><A><G><R><S><C><Q><E><V><L><R><K><G><C><L><R><F><Q><L><P><E><R><G><S><R><L><C><L><Y><E><D><G><T><E><L><T><E><D><Y><F><P><S><V><P><D><N><A><E><L><V><L><L><T><L><G><Q><A><W><Q><G><Y><V><S><D><I><R><R><F><L><S><A><F><H><E><P><Q><V><G><L><I><Q><A><A><Q><Q><L><L><C><D><E><Q><A><P><Q><R><Q><R><L><L><A><D><L><L><H><N><V><S><Q><N><I><A><A><E><T><R><A><E><D><P><P><W><F><E><G><L><E><S><R><F><Q><S><K><S><G><Y><L><R><Y><S><C><E><S><R><I><R><S><Y><L><R><E><V><S><S><Y><P><S><T><V><G><A><E><A><Q><E><E><F><L><R><V><L><G><S><M><C><Q><R><L><R><S><M><Q><Y><N><G><S><Y><F><D><R><G><A><K><G><G><S><R><L><C><T><P><E><G><W><F><S><C><Q><G><P><F><D><M><D><S><C><L><S><R><H><S><I><N><P><Y><S><N><R><E><S><R><I><L><F><S><T><W><N><L><D><H><I><I><E><K><K><R><T><I><I><P><T><L><V><E><A><I><K><E><Q><D><G><R><E><V><D><W><E><Y><F><Y><G><L><L><F><T><S><E><N><L><K><L><V><H><I><V><C><H><K><K><T><T><H><K><L><N><C><D><P><S><R><I><Y><K><P><Q><T><R><L><K><R><K><Q><P><V><R><K><R><Q>
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.<BOP>
O76075
O15541
R113A_HUMAN
Zinc finger protein 183
Homo
<M><A><E><Q><L><S><P><G><K><A><V><D><Q><V><C><T><F><L><F><K><K><P><G><R><K><G><A><A><G><R><R><K><R><P><A><C><D><P><E><P><G><E><S><G><S><S><S><D><E><G><C><T><V><V><R><P><E><K><K><R><V><T><H><N><P><M><I><Q><K><T><R><D><S><G><K><Q><K><A><A><Y><G><D><L><S><S><E><E><E><E><E><N><E><P><E><S><L><G><V><V><Y><K><S><T><R><S><A><K><P><V><G><P><E><D><M><G><A><T><A><V><Y><E><L><D><T><E><K><E><R><D><A><Q><A><I><F><E><R><S><Q><K><I><Q><E><E><L><R><G><K><E><D><D><K><I><Y><R><G><I><N><N><Y><Q><K><Y><M><K><P><K><D><T><S><M><G><N><A><S><S><G><M><V><R><K><G><P><I><R><A><P><E><H><L><R><A><T><V><R><W><D><Y><Q><P><D><I><C><K><D><Y><K><E><T><G><F><C><G><F><G><D><S><C><K><F><L><H><D><R><S><D><Y><K><H><G><W><Q><I><E><R><E><L><D><E><G><R><Y><G><V><Y><E><D><E><N><Y><E><V><G><S><D><D><E><E><I><P><F><K><C><F><I><C><R><Q><S><F><Q><N><P><V><V><T><K><C><R><H><Y><F><C><E><S><C><A><L><Q><H><F><R><T><T><P><R><C><Y><V><C><D><Q><Q><T><N><G><V><F><N><P><A><K><E><L><I><A><K><L><E><K><H><R><A><T><G><E><G><G><A><S><D><L><P><E><D><P><D><E><D><A><I><P><I><T>
Required for pre-mRNA splicing as component of the spliceosome . E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins . Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains . Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents . Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling .<BOP>
O15541
Q8NGL4
OR5DD_HUMAN
Olfactory receptor OR11-148
Homo
<M><M><A><S><E><R><N><Q><S><S><T><P><T><F><I><L><L><G><F><S><E><Y><P><E><I><Q><V><P><L><F><L><V><F><L><F><V><Y><T><V><T><V><V><G><N><L><G><M><I><I><I><I><R><L><N><S><K><L><H><T><I><M><C><F><F><L><S><H><L><S><L><T><D><F><C><F><S><T><V><V><T><P><K><L><L><E><N><L><V><V><E><Y><R><T><I><S><F><S><G><C><I><M><Q><F><C><F><A><C><I><F><G><V><T><E><T><F><M><L><A><A><M><A><Y><D><R><F><V><A><V><C><K><P><L><L><Y><T><T><I><M><S><Q><K><L><C><A><L><L><V><A><G><S><Y><T><W><G><I><V><C><S><L><I><L><T><Y><F><L><L><D><L><S><F><C><E><S><T><F><I><N><N><F><I><C><D><H><S><V><I><V><S><A><S><Y><S><D><P><Y><I><S><Q><R><L><C><F><I><I><A><I><F><N><E><V><S><S><L><I><I><I><L><T><S><Y><M><L><I><F><T><T><I><M><K><M><R><S><A><S><G><R><Q><K><T><F><S><T><C><A><S><H><L><T><A><I><T><I><F><H><G><T><I><L><F><L><Y><C><V><P><N><P><K><T><S><S><L><I><V><T><V><A><S><V><F><Y><T><V><A><I><P><M><L><N><P><L><I><Y><S><L><R><N><K><D><I><N><N><M><F><E><K><L><V><V><T><K><L><I><Y><H>
Odorant receptor.<BOP>
Q8NGL4
Q9NS67
GPR27_HUMAN
Super conserved receptor expressed in brain 1
Homo
<M><A><N><A><S><E><P><G><G><S><G><G><G><E><A><A><A><L><G><L><K><L><A><T><L><S><L><L><L><C><V><S><L><A><G><N><V><L><F><A><L><L><I><V><R><E><R><S><L><H><R><A><P><Y><Y><L><L><L><D><L><C><L><A><D><G><L><R><A><L><A><C><L><P><A><V><M><L><A><A><R><R><A><A><A><A><A><G><A><P><P><G><A><L><G><C><K><L><L><A><F><L><A><A><L><F><C><F><H><A><A><F><L><L><L><G><V><G><V><T><R><Y><L><A><I><A><H><H><R><F><Y><A><E><R><L><A><G><W><P><C><A><A><M><L><V><C><A><A><W><A><L><A><L><A><A><A><F><P><P><V><L><D><G><G><G><D><D><E><D><A><P><C><A><L><E><Q><R><P><D><G><A><P><G><A><L><G><F><L><L><L><L><A><V><V><V><G><A><T><H><L><V><Y><L><R><L><L><F><F><I><H><D><R><R><K><M><R><P><A><R><L><V><P><A><V><S><H><D><W><T><F><H><G><P><G><A><T><G><Q><A><A><A><N><W><T><A><G><F><G><R><G><P><T><P><P><A><L><V><G><I><R><P><A><G><P><G><R><G><A><R><R><L><L><V><L><E><E><F><K><T><E><K><R><L><C><K><M><F><Y><A><V><T><L><L><F><L><L><L><W><G><P><Y><V><V><A><S><Y><L><R><V><L><V><R><P><G><A><V><P><Q><A><Y><L><T><A><S><V><W><L><T><F><A><Q><A><G><I><N><P><V><V><C><F><L><F><N><R><E><L><R><D><C><F><R><A><Q><F><P><C><C><Q><S><P><R><T><T><Q><A><T><H><P><C><D><L><K><G><I><G><L>
Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.<BOP>
Q9NS67
P0DM35
M1BL1_HUMAN
Metallothionein 1H-like protein 1
Homo
<M><D><P><N><C><S><C><A><A><G><G><S><Y><A><C><A><G><S><C><K><C><K><K><C><K><C><T><S><C><K><K><S><C><C><S><C><C><P><L><G><C><A><K><C><A><Q><G><C><I><R><K><G><A><S><E><K><C><S><C><C><A>
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.<BOP>
P0DM35
O00409
FOXN3_HUMAN
Checkpoint suppressor 1
Homo
<M><G><P><V><M><P><P><S><K><K><P><E><S><S><G><I><S><V><S><S><G><L><S><Q><C><Y><G><G><S><G><F><S><K><A><L><Q><E><D><D><D><L><D><F><S><L><P><D><I><R><L><E><E><G><A><M><E><D><E><E><L><T><N><L><N><W><L><H><E><S><K><N><L><L><K><S><F><G><E><S><V><L><R><S><V><S><P><V><Q><D><L><D><D><D><T><P><P><S><P><A><H><S><D><M><P><Y><D><A><R><Q><N><P><N><C><K><P><P><Y><S><F><S><C><L><I><F><M><A><I><E><D><S><P><T><K><R><L><P><V><K><D><I><Y><N><W><I><L><E><H><F><P><Y><F><A><N><A><P><T><G><W><K><N><S><V><R><H><N><L><S><L><N><K><C><F><K><K><V><D><K><E><R><S><Q><S><I><G><K><G><S><L><W><C><I><D><P><E><Y><R><Q><N><L><I><Q><A><L><K><K><T><P><Y><H><P><H><P><H><V><F><N><T><P><P><T><C><P><Q><A><Y><Q><S><T><S><G><P><P><I><W><P><G><S><T><F><F><K><R><N><G><A><L><L><Q><D><P><D><I><D><A><A><S><A><M><M><L><L><N><T><P><P><E><I><Q><A><G><F><P><P><G><V><I><Q><N><G><A><R><V><L><S><R><G><L><F><P><G><V><R><P><L><P><I><T><P><I><G><V><T><A><A><M><R><N><G><I><T><S><C><R><M><R><T><E><S><E><P><S><C><G><S><P><V><V><S><G><D><P><K><E><D><H><N><Y><S><S><A><K><S><S><N><A><R><S><T><S><P><T><S><D><S><I><S><S><S><S><S><S><A><D><D><H><Y><E><F><A><T><K><G><S><Q><E><G><S><E><G><S><E><G><S><F><R><S><H><E><S><P><S><D><T><E><E><D><D><R><K><H><S><Q><K><E><P><K><D><S><L><G><D><S><G><Y><A><S><Q><H><K><K><R><Q><H><F><A><K><A><R><K><V><P><S><D><T><L><P><L><K><K><R><R><T><E><K><P><P><E><S><D><D><E><E><M><K><E><A><A><G><S><L><L><H><L><A><G><I><R><S><C><L><N><N><I><T><N><R><T><A><K><G><Q><K><E><Q><K><E><T><T><K><N>
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).<BOP>
O00409
Q9BR10
SPT25_HUMAN
Testis-specific gene 23 protein
Homo
<M><S><Y><F><R><T><P><Q><T><H><P><G><P><L><P><S><G><Q><G><G><A><A><S><P><G><L><S><L><G><L><C><S><P><V><E><P><V><V><V><A><S><G><G><T><G><P><L><S><Q><K><A><E><Q><V><A><P><A><A><Q><A><W><G><P><A><L><A><M><P><Q><A><R><G><C><P><G><G><T><S><W><E><T><L><R><K><E><Y><S><R><N><C><H><K><F><P><H><V><R><Q><L><E><S><L><G><W><D><N><G><Y><S><R><S><R><A><P><D><L><G><G><P><S><R><P><R><P><L><M><L><C><G><L><S><P><R><V><L><P><V><P><S><E><A><V><G><K><E><A><S><S><Q><P><D><I><C><I><L><T><L><A><M><M><I><A><G><I><P><T><V><P><V><P><G><V><R><E><E><D><L><I><W><A><A><Q><A><F><M><M><A><H><P><E><P><E><G><A><V><E><G><A><R><W><E><Q><A><H><A><H><T><A><S><G><K><M><P><L><V><R><S><K><R><G><Q><P><P><G><S><C><L>
May play a role in spermatogenesis.<BOP>
Q9BR10
Q96QZ0
PANX3_HUMAN
Pannexin-3
Homo
<M><S><L><A><H><T><A><A><E><Y><M><L><S><D><A><L><L><P><D><R><R><G><P><R><L><K><G><L><R><L><E><L><P><L><D><R><I><V><K><F><V><A><V><G><S><P><L><L><L><M><S><L><A><F><A><Q><E><F><S><S><G><S><P><I><S><C><F><S><P><S><N><F><S><I><R><Q><A><A><Y><V><D><S><S><C><W><D><S><L><L><H><H><K><Q><D><G><P><G><Q><D><K><M><K><S><L><W><P><H><K><A><L><P><Y><S><L><L><A><L><A><L><L><M><Y><L><P><V><L><L><W><Q><Y><A><A><V><P><A><L><S><S><D><L><L><F><I><I><S><E><L><D><K><S><Y><N><R><S><I><R><L><V><Q><H><M><L><K><I><R><Q><K><S><S><D><P><Y><V><F><W><N><E><L><E><K><A><R><K><E><R><Y><F><E><F><P><L><L><E><R><Y><L><A><C><K><Q><R><S><H><S><L><V><A><T><Y><L><L><R><N><S><L><L><L><I><F><T><S><A><T><Y><L><Y><L><G><H><F><H><L><D><V><F><F><Q><E><E><F><S><C><S><I><K><T><G><L><L><S><D><E><T><H><V><P><N><L><I><T><C><R><L><T><S><L><S><I><F><Q><I><V><S><L><S><S><V><A><I><Y><T><I><L><V><P><V><I><I><Y><N><L><T><R><L><C><R><W><D><K><R><L><L><S><V><Y><E><M><L><P><A><F><D><L><L><S><R><K><M><L><G><C><P><I><N><D><L><N><V><I><L><L><F><L><R><A><N><I><S><E><L><I><S><F><S><W><L><S><V><L><C><V><L><K><D><T><T><T><Q><K><H><N><I><D><T><V><V><D><F><M><T><L><L><A><G><L><E><P><S><K><P><K><H><L><T><N><S><A><C><D><E><H><P>
Structural component of the gap junctions and the hemichannels.<BOP>
Q96QZ0
Q15286
RAB35_HUMAN
Ras-related protein Rab-1C
Homo
<M><A><R><D><Y><D><H><L><F><K><L><L><I><I><G><D><S><G><V><G><K><S><S><L><L><L><R><F><A><D><N><T><F><S><G><S><Y><I><T><T><I><G><V><D><F><K><I><R><T><V><E><I><N><G><E><K><V><K><L><Q><I><W><D><T><A><G><Q><E><R><F><R><T><I><T><S><T><Y><Y><R><G><T><H><G><V><I><V><V><Y><D><V><T><S><A><E><S><F><V><N><V><K><R><W><L><H><E><I><N><Q><N><C><D><D><V><C><R><I><L><V><G><N><K><N><D><D><P><E><R><K><V><V><E><T><E><D><A><Y><K><F><A><G><Q><M><G><I><Q><L><F><E><T><S><A><K><E><N><V><N><V><E><E><M><F><N><C><I><T><E><L><V><L><R><A><K><K><D><N><L><A><K><Q><Q><Q><Q><Q><Q><N><D><V><V><K><L><T><K><N><S><K><R><K><K><R><C><C>
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.<BOP>
Q15286
Q9NX95
SYBU_HUMAN
Syntaxin-1-binding protein
Homo
<M><G><P><L><R><E><S><K><K><E><H><R><V><Q><H><H><D><K><E><I><S><R><S><R><I><P><R><L><I><L><R><P><H><M><P><Q><Q><Q><H><K><V><S><P><A><S><E><S><P><F><S><E><E><E><S><R><E><F><N><P><S><S><S><G><R><S><A><R><T><V><S><S><N><S><F><C><S><D><D><T><G><C><P><S><S><Q><S><V><S><P><V><K><T><P><S><D><A><G><N><S><P><I><G><F><C><P><G><S><D><E><G><F><T><R><K><K><C><T><I><G><M><V><G><E><G><S><I><Q><S><S><R><Y><K><K><E><S><K><S><G><L><V><K><P><G><S><E><A><D><F><S><S><S><S><S><T><G><S><I><S><A><P><E><V><H><M><S><T><A><G><S><K><R><S><S><S><S><R><N><R><G><P><H><G><R><S><N><G><A><S><S><H><K><P><G><S><S><P><S><S><P><R><E><K><D><L><L><S><M><L><C><R><N><Q><L><S><P><V><N><I><H><P><S><Y><A><P><S><S><P><S><S><S><N><S><G><S><Y><K><G><S><D><C><S><P><I><M><R><R><S><G><R><Y><M><S><C><G><E><N><H><G><V><R><P><P><N><P><E><Q><Y><L><T><P><L><Q><Q><K><E><V><T><V><R><H><L><K><T><K><L><K><E><S><E><R><R><L><H><E><R><E><S><E><I><V><E><L><K><S><Q><L><A><R><M><R><E><D><W><I><E><E><E><C><H><R><V><E><A><Q><L><A><L><K><E><A><R><K><E><I><K><Q><L><K><Q><V><I><E><T><M><R><S><S><L><A><D><K><D><K><G><I><Q><K><Y><F><V><D><I><N><I><Q><N><K><K><L><E><S><L><L><Q><S><M><E><M><A><H><S><G><S><L><R><D><E><L><C><L><D><F><P><C><D><S><P><E><K><S><L><T><L><N><P><P><L><D><T><M><A><D><G><L><S><L><E><E><Q><V><T><G><E><G><A><D><R><E><L><L><V><G><D><S><I><A><N><S><T><D><L><F><D><E><I><V><T><A><T><T><T><E><S><G><D><L><E><L><V><H><S><T><P><G><A><N><V><L><E><L><L><P><I><V><M><G><Q><E><E><G><S><V><V><V><E><R><A><V><Q><T><D><V><V><P><Y><S><P><A><I><S><E><L><I><Q><S><V><L><Q><K><L><Q><D><P><C><P><S><S><L><A><S><P><D><E><S><E><P><D><S><M><E><S><F><P><E><S><L><S><A><L><V><V><D><L><T><P><R><N><P><N><S><A><I><L><L><S><P><V><E><T><P><Y><A><N><V><D><A><E><V><H><A><N><R><L><M><R><E><L><D><F><A><A><C><V><E><E><R><L><D><G><V><I><P><L><A><R><G><G><V><V><R><Q><Y><W><S><S><S><F><L><V><D><L><L><A><V><A><A><P><V><V><P><T><V><L><W><A><F><S><T><Q><R><G><G><T><D><P><V><Y><N><I><G><A><L><L><R><G><C><C><V><V><A><L><H><S><L><R><R><T><A><F><R><I><K><T>
Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.<BOP>
Q9NX95
Q8NGM8
OR6M1_HUMAN
Olfactory receptor OR11-271
Homo
<M><G><N><W><S><T><V><T><E><I><T><L><I><A><F><P><A><L><L><E><I><R><I><S><L><F><V><V><L><V><V><T><Y><T><L><T><A><T><G><N><I><T><I><I><S><L><I><W><I><D><H><R><L><Q><T><P><M><Y><F><F><L><S><N><L><S><F><L><D><I><L><Y><T><T><V><I><T><P><K><L><L><A><C><L><L><G><E><E><K><T><I><S><F><A><G><C><M><I><Q><T><Y><F><Y><F><F><L><G><T><V><E><F><I><L><L><A><V><M><S><F><D><R><Y><M><A><I><C><D><P><L><H><Y><T><V><I><M><N><S><R><A><C><L><L><L><V><L><G><C><W><V><G><A><F><L><S><V><L><F><P><T><I><V><V><T><R><L><P><Y><C><R><K><E><I><N><H><F><F><C><D><I><A><P><L><L><Q><V><A><C><I><N><T><H><L><I><E><K><I><N><F><L><L><S><A><L><V><I><L><S><S><L><A><F><T><T><G><S><Y><V><Y><I><I><S><T><I><L><R><I><P><S><T><Q><G><R><Q><K><A><F><S><T><C><A><S><H><I><T><V><V><S><I><A><H><G><S><N><I><F><V><Y><V><R><P><N><Q><N><S><S><L><D><Y><D><K><V><A><A><V><L><I><T><V><V><T><P><L><L><N><P><F><I><Y><S><L><R><N><E><K><V><Q><E><V><L><R><E><T><V><N><R><I><M><T><L><I><Q><R><K><T>
Odorant receptor.<BOP>
Q8NGM8
Q6P2D0
ZFP1_HUMAN
Zinc finger protein 475
Homo
<M><N><K><S><Q><G><S><V><S><F><T><D><V><T><V><D><F><T><Q><E><E><W><E><Q><L><D><P><S><Q><R><I><L><Y><M><D><V><M><L><E><N><Y><S><N><L><L><S><V><E><V><W><K><A><D><D><Q><M><E><R><D><H><R><N><P><D><E><Q><A><R><Q><F><L><I><L><K><N><Q><T><P><I><E><E><R><G><D><L><F><G><K><A><L><N><L><N><T><D><F><V><S><L><R><Q><V><P><Y><K><Y><D><L><Y><E><K><T><L><K><Y><N><S><D><L><L><N><S><N><R><S><Y><A><G><K><Q><T><D><E><C><N><E><F><G><K><A><L><L><Y><L><K><Q><E><K><T><H><S><G><V><E><Y><S><E><Y><N><K><S><G><K><A><L><S><H><K><A><A><I><F><K><H><Q><K><I><K><N><L><V><Q><P><F><I><C><T><Y><C><D><K><A><F><S><F><K><S><L><L><I><S><H><K><R><I><H><T><G><E><K><P><Y><E><C><N><V><C><K><K><T><F><S><H><K><A><N><L><I><K><H><Q><R><I><H><T><G><E><K><P><F><E><C><P><E><C><G><K><A><F><T><H><Q><S><N><L><I><V><H><Q><R><A><H><M><E><K><K><P><Y><E><C><S><E><C><G><K><T><F><A><Q><K><F><E><L><T><T><H><Q><R><I><H><T><G><E><R><P><Y><E><C><N><E><C><A><K><T><F><F><K><K><S><N><L><I><I><H><Q><K><I><H><T><G><E><K><R><Y><E><C><S><E><C><G><K><S><F><I><Q><N><S><Q><L><I><I><H><M><R><T><H><T><G><E><K><P><Y><E><C><T><E><C><G><K><T><F><S><Q><R><S><T><L><R><L><H><L><R><I><H><T><G><E><K><P><Y><E><C><S><E><C><G><K><A><F><S><R><K><S><R><L><S><V><H><Q><R><V><H><I><G><E><K><P>
May be involved in transcriptional regulation.<BOP>
Q6P2D0
O60431
OR1I1_HUMAN
Olfactory receptor 19-20
Homo
<M><E><P><E><K><Q><T><E><I><S><E><F><F><L><Q><G><L><S><E><K><P><E><H><Q><T><L><L><F><T><M><F><L><S><T><Y><L><V><T><I><I><G><N><A><L><I><I><L><A><I><I><T><D><S><H><L><H><T><P><M><Y><F><F><L><F><N><L><S><L><V><D><T><L><L><S><S><T><T><V><P><K><M><L><A><N><I><Q><A><Q><S><R><A><I><P><F><V><G><C><L><T><Q><M><Y><A><F><H><L><F><G><T><M><D><S><F><L><L><A><V><M><A><I><D><R><F><V><A><I><V><H><P><Q><R><Y><L><V><L><M><C><S><P><V><C><G><L><L><L><G><A><S><W><M><I><T><N><L><Q><S><L><I><H><T><C><L><M><A><Q><L><T><F><C><A><G><S><E><I><S><H><F><F><C><D><L><M><P><L><L><K><L><S><G><S><D><T><H><T><N><E><L><V><I><F><A><F><G><I><V><V><G><T><S><P><F><S><C><I><L><L><S><Y><I><R><I><F><W><T><V><F><K><I><P><S><T><R><G><K><W><K><A><F><S><T><C><G><L><H><L><T><V><V><S><L><S><Y><G><T><I><F><A><V><Y><L><Q><P><T><S><P><S><S><S><Q><K><D><K><A><A><A><L><M><C><G><V><F><I><P><M><L><N><P><F><I><Y><S><I><R><N><K><D><M><K><A><A><L><G><K><L><I><G><K><V><A><V><P><C><P><R><P><E><Q><L><L><D><V><Y><H><V><P><G><S><L><L><A><A><R><D><T><E><M><H><P><I><P><Y><P><G><G><V><Q><S><L><A><G><N><R><D><M><E>
Odorant receptor.<BOP>
O60431
P29016
CD1B_HUMAN
T-cell surface glycoprotein CD1b
Homo
<M><L><L><L><P><F><Q><L><L><A><V><L><F><P><G><G><N><S><E><H><A><F><Q><G><P><T><S><F><H><V><I><Q><T><S><S><F><T><N><S><T><W><A><Q><T><Q><G><S><G><W><L><D><D><L><Q><I><H><G><W><D><S><D><S><G><T><A><I><F><L><K><P><W><S><K><G><N><F><S><D><K><E><V><A><E><L><E><E><I><F><R><V><Y><I><F><G><F><A><R><E><V><Q><D><F><A><G><D><F><Q><M><K><Y><P><F><E><I><Q><G><I><A><G><C><E><L><H><S><G><G><A><I><V><S><F><L><R><G><A><L><G><G><L><D><F><L><S><V><K><N><A><S><C><V><P><S><P><E><G><G><S><R><A><Q><K><F><C><A><L><I><I><Q><Y><Q><G><I><M><E><T><V><R><I><L><L><Y><E><T><C><P><R><Y><L><L><G><V><L><N><A><G><K><A><D><L><Q><R><Q><V><K><P><E><A><W><L><S><S><G><P><S><P><G><P><G><R><L><Q><L><V><C><H><V><S><G><F><Y><P><K><P><V><W><V><M><W><M><R><G><E><Q><E><Q><Q><G><T><Q><L><G><D><I><L><P><N><A><N><W><T><W><Y><L><R><A><T><L><D><V><A><D><G><E><A><A><G><L><S><C><R><V><K><H><S><S><L><E><G><Q><D><I><I><L><Y><W><R><N><P><T><S><I><G><S><I><V><L><A><I><I><V><P><S><L><L><L><L><L><C><L><A><L><W><Y><M><R><R><R><S><Y><Q><N><I><P>
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.<BOP>
P29016
Q86V71
ZN429_HUMAN
Zinc finger protein 429
Homo
<M><G><P><L><T><F><T><D><V><A><I><E><F><S><L><E><E><W><Q><C><L><D><T><A><Q><Q><N><L><Y><R><N><V><M><L><E><N><Y><R><N><L><V><F><L><G><I><A><V><S><K><P><D><L><I><T><C><L><E><K><E><K><E><P><C><K><M><K><R><H><E><M><V><D><E><P><P><V><V><C><S><H><F><A><E><D><F><W><P><E><Q><D><I><K><D><S><F><Q><K><V><T><L><R><R><Y><D><K><R><G><H><E><N><L><Q><L><R><K><G><Y><K><T><V><G><D><C><K><L><Y><K><G><G><Y><N><G><L><N><Q><C><L><T><L><T><Q><S><K><M><Y><H><C><D><I><Y><V><K><V><F><Y><A><F><S><N><A><D><R><Y><K><T><R><H><T><G><K><K><P><F><Q><C><K><K><C><G><K><S><F><C><M><L><S><Q><L><T><Q><H><K><K><I><H><I><R><E><N><T><Y><R><C><K><E><F><G><N><A><F><N><Q><S><S><A><L><T><N><H><K><R><I><Y><V><G><E><K><H><Y><R><C><E><E><C><G><K><A><F><N><H><Y><S><T><L><T><N><H><K><R><I><H><T><G><E><K><P><Y><K><C><K><E><C><G><K><A><F><S><R><Y><S><T><L><T><T><H><K><R><I><H><S><G><E><K><P><Y><K><C><D><E><C><G><K><T><F><S><I><S><S><T><F><T><K><H><K><I><I><H><T><E><E><K><P><Y><K><C><K><E><C><G><K><A><F><N><R><S><S><T><L><T><S><H><K><R><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><N><W><S><S><T><L><T><K><H><K><V><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><N><Q><S><S><R><L><T><R><H><K><K><I><H><T><G><E><E><P><Y><K><F><E><K><C><G><R><V><F><T><C><S><S><T><L><T><Q><D><K><K><I><H><T><G><E><K><P><Y><N><C><E><E><C><G><K><V><F><T><Y><S><S><T><L><T><R><H><K><R><I><H><T><E><E><K><P><Y><K><C><N><E><C><G><K><A><F><N><R><S><S><H><L><T><S><H><R><R><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><K><Q><S><S><N><L><N><S><H><K><K><I><H><S><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><I><L><S><S><R><L><T><Q><H><K><K><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><N><R><S><S><R><L><T><Q><H><K><K><I><H><T><G><E><K><P><Y><K><C><K><Q><C><D><K><A><F><T><H><S><S><N><L><S><S><H><K><K><I><H><S><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><N><R><S><S><R><L><T><Q><H><K><K><I><H><T><R><E><K><P><Y><K><C><E><E><C><A><K><A><F><T><R><S><S><R><L><T><Q><H><K><K><I><H><R><M><G><V><V><A><H><A><C><N><P><S><T><L><G><G><R><G><G><R><I><T><R><S><G><D><R><D><R><P><G>
May be involved in transcriptional regulation.<BOP>
Q86V71
Q8WVK7
SKA2_HUMAN
Protein FAM33A
Homo
<M><E><A><E><V><D><K><L><E><L><M><F><Q><K><A><E><S><D><L><D><Y><I><Q><Y><R><L><E><Y><E><I><K><T><N><H><P><D><S><A><S><E><K><N><P><V><T><L><L><K><E><L><S><V><I><K><S><R><Y><Q><T><L><Y><A><R><F><K><P><V><A><V><E><Q><K><E><S><K><S><R><I><C><A><T><V><K><K><T><M><N><M><I><Q><K><L><Q><K><Q><T><D><L><E><L><S><P><L><T><K><E><E><K><T><A><A><E><Q><F><K><F><H><M><P><D><L>
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation . Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint . The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies . The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner . In the complex, it is required for SKA1 localization . Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules .<BOP>
Q8WVK7
P06454
PTMA_HUMAN
Thymosin alpha-1
Homo
<M><S><D><A><A><V><D><T><S><S><E><I><T><T><K><D><L><K><E><K><K><E><V><V><E><E><A><E><N><G><R><D><A><P><A><N><G><N><A><E><N><E><E><N><G><E><Q><E><A><D><N><E><V><D><E><E><E><E><E><G><G><E><E><E><E><E><E><E><E><G><D><G><E><E><E><D><G><D><E><D><E><E><A><E><S><A><T><G><K><R><A><A><E><D><D><E><D><D><D><V><D><T><K><K><Q><K><T><D><E><D><D>
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.<BOP>
P06454
P10265
VPK10_HUMAN
Proteinase
Homo
<W><A><S><Q><V><S><E><N><R><P><V><C><K><A><I><I><Q><G><K><Q><F><E><G><L><V><D><T><G><A><D><V><S><I><I><A><L><N><Q><W><P><K><N><W><P><K><Q><K><A><V><T><G><L><V><G><I><G><T><A><S><E><V><Y><Q><S><M><E><I><L><H><C><L><G><P><D><N><Q><E><S><T><V><Q><P><M><I><T><S><I><P><L><N><L><W><G><R><D><L><L><Q><Q><W><G><A><E><I><T><M><P><A><P><L><Y><S><P><T><S><Q><K><I><M><T><K><M><G><Y><I><P><G><K><G><L><G><K><N><E><D><G><I><K><V><P><V><E><A><K><I><N><Q><E><R><E><G><I><G><Y><P><F>
Retroviral proteases have roles in processing of the primary translation products and the maturation of the viral particle. Endogenous Pro proteins may have kept, lost or modified their original function during evolution. This endogenous protein has retained most of the characteristics of retroviral proteases.<BOP>
P10265
P10451
OSTP_HUMAN
Uropontin
Homo
<M><R><I><A><V><I><C><F><C><L><L><G><I><T><C><A><I><P><V><K><Q><A><D><S><G><S><S><E><E><K><Q><L><Y><N><K><Y><P><D><A><V><A><T><W><L><N><P><D><P><S><Q><K><Q><N><L><L><A><P><Q><N><A><V><S><S><E><E><T><N><D><F><K><Q><E><T><L><P><S><K><S><N><E><S><H><D><H><M><D><D><M><D><D><E><D><D><D><D><H><V><D><S><Q><D><S><I><D><S><N><D><S><D><D><V><D><D><T><D><D><S><H><Q><S><D><E><S><H><H><S><D><E><S><D><E><L><V><T><D><F><P><T><D><L><P><A><T><E><V><F><T><P><V><V><P><T><V><D><T><Y><D><G><R><G><D><S><V><V><Y><G><L><R><S><K><S><K><K><F><R><R><P><D><I><Q><Y><P><D><A><T><D><E><D><I><T><S><H><M><E><S><E><E><L><N><G><A><Y><K><A><I><P><V><A><Q><D><L><N><A><P><S><D><W><D><S><R><G><K><D><S><Y><E><T><S><Q><L><D><D><Q><S><A><E><T><H><S><H><K><Q><S><R><L><Y><K><R><K><A><N><D><E><S><N><E><H><S><D><V><I><D><S><Q><E><L><S><K><V><S><R><E><F><H><S><H><E><F><H><S><H><E><D><M><L><V><V><D><P><K><S><K><E><E><D><K><H><L><K><F><R><I><S><H><E><L><D><S><A><S><S><E><V><N>
Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.<BOP>
P10451
P23759
PAX7_HUMAN
HuP1
Homo
<M><A><A><L><P><G><T><V><P><R><M><M><R><P><A><P><G><Q><N><Y><P><R><T><G><F><P><L><E><V><S><T><P><L><G><Q><G><R><V><N><Q><L><G><G><V><F><I><N><G><R><P><L><P><N><H><I><R><H><K><I><V><E><M><A><H><H><G><I><R><P><C><V><I><S><R><Q><L><R><V><S><H><G><C><V><S><K><I><L><C><R><Y><Q><E><T><G><S><I><R><P><G><A><I><G><G><S><K><P><R><Q><V><A><T><P><D><V><E><K><K><I><E><E><Y><K><R><E><N><P><G><M><F><S><W><E><I><R><D><R><L><L><K><D><G><H><C><D><R><S><T><V><P><S><G><L><V><S><S><I><S><R><V><L><R><I><K><F><G><K><K><E><E><E><D><E><A><D><K><K><E><D><D><G><E><K><K><A><K><H><S><I><D><G><I><L><G><D><K><G><N><R><L><D><E><G><S><D><V><E><S><E><P><D><L><P><L><K><R><K><Q><R><R><S><R><T><T><F><T><A><E><Q><L><E><E><L><E><K><A><F><E><R><T><H><Y><P><D><I><Y><T><R><E><E><L><A><Q><R><T><K><L><T><E><A><R><V><Q><V><W><F><S><N><R><R><A><R><W><R><K><Q><A><G><A><N><Q><L><A><A><F><N><H><L><L><P><G><G><F><P><P><T><G><M><P><T><L><P><P><Y><Q><L><P><D><S><T><Y><P><T><T><T><I><S><Q><D><G><G><S><T><V><H><R><P><Q><P><L><P><P><S><T><M><H><Q><G><G><L><A><A><A><A><A><A><A><D><T><S><S><A><Y><G><A><R><H><S><F><S><S><Y><S><D><S><F><M><N><P><A><A><P><S><N><H><M><N><P><V><S><N><G><L><S><P><Q><V><M><S><I><L><G><N><P><S><A><V><P><P><Q><P><Q><A><D><F><S><I><S><P><L><H><G><G><L><D><S><A><T><S><I><S><A><S><C><S><Q><R><A><D><S><I><K><P><G><D><S><L><P><T><S><Q><A><Y><C><P><P><T><Y><S><T><T><G><Y><S><V><D><P><V><A><G><Y><Q><Y><G><Q><Y><G><Q><T><A><V><D><Y><L><A><K><N><V><S><L><S><T><Q><R><R><M><K><L><G><E><H><S><A><V><L><G><L><L><P><V><E><T><G><Q><A><Y>
Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration.<BOP>
P23759
A8MX76
CAN14_HUMAN
Calcium-activated neutral proteinase 14
Homo
<M><S><L><W><P><P><F><R><C><R><W><K><L><A><P><R><Y><S><R><R><A><S><P><Q><Q><P><Q><Q><D><F><E><A><L><L><A><E><C><L><R><N><G><C><L><F><E><D><T><S><F><P><A><T><L><S><S><I><G><S><G><S><L><L><Q><K><L><P><P><R><L><Q><W><K><R><P><P><E><L><H><S><N><P><Q><F><Y><F><A><K><A><K><R><L><D><L><C><Q><G><I><V><G><D><C><W><F><L><A><A><L><Q><A><L><A><L><H><Q><D><I><L><S><R><V><V><P><L><N><Q><S><F><T><E><K><Y><A><G><I><F><R><F><W><F><W><H><Y><G><N><W><V><P><V><V><I><D><D><R><L><P><V><N><E><A><G><Q><L><V><F><V><S><S><T><Y><K><N><L><F><W><G><A><L><L><E><K><A><Y><A><K><L><S><G><S><Y><E><D><L><Q><S><G><Q><V><S><E><A><L><V><D><F><T><G><G><V><T><M><T><I><N><L><A><E><A><H><G><N><L><W><D><I><L><I><E><A><T><Y><N><R><T><L><I><G><C><Q><T><H><S><G><E><K><I><L><E><N><G><L><V><E><G><H><A><Y><T><L><T><G><I><R><K><V><T><C><K><H><R><P><E><Y><L><V><K><L><R><N><P><W><G><K><V><E><W><K><G><D><W><S><D><S><S><S><K><W><E><L><L><S><P><K><E><K><I><L><L><L><R><K><D><N><D><G><E><F><W><M><T><L><Q><D><F><K><T><H><F><V><L><L><V><I><C><K><L><T><P><G><L><L><S><Q><E><A><A><Q><K><W><T><Y><T><M><R><E><G><R><W><E><K><R><S><T><A><G><G><Q><R><Q><L><L><Q><D><T><F><W><K><N><P><Q><F><L><L><S><V><W><R><P><E><E><G><R><R><S><L><R><P><C><S><V><L><V><S><L><L><Q><K><P><R><H><R><C><R><K><R><K><P><L><L><A><I><G><F><Y><L><Y><R><M><N><K><Y><H><D><D><Q><R><R><L><P><P><E><F><F><Q><R><N><T><P><L><S><Q><P><D><R><F><L><K><E><K><E><V><S><Q><E><L><C><L><E><P><G><T><Y><L><I><V><P><C><I><L><E><A><H><Q><K><S><E><F><V><L><R><V><F><S><R><K><H><I><F><Y><E><I><G><S><N><S><G><V><V><F><S><K><E><I><E><D><Q><N><E><R><Q><D><E><F><F><T><K><F><F><E><K><H><P><E><I><N><A><V><Q><L><Q><N><L><L><N><Q><M><T><W><S><S><L><G><S><R><Q><P><F><F><S><L><E><A><C><Q><G><I><L><A><L><L><D><L><N><A><S><G><T><M><S><I><Q><E><F><R><D><L><W><K><Q><L><K><L><S><Q><K><V><F><H><K><Q><D><R><G><S><G><Y><L><N><W><E><Q><L><H><A><A><M><R><E><A><G><I><M><L><S><D><D><V><C><Q><L><M><L><I><R><Y><G><G><P><R><L><Q><M><D><F><V><S><F><I><H><L><M><L><R><V><E><N><M><E><D><V><F><Q><N><L><T><Q><D><G><K><G><I><Y><L><Q><K><P><E><W><M><M><M><A><L><Y><S>
Calcium-regulated non-lysosomal thiol-protease.<BOP>
A8MX76
O95377
CXB5_HUMAN
Connexin-31.1
Homo
<M><N><W><S><I><F><E><G><L><L><S><G><V><N><K><Y><S><T><A><F><G><R><I><W><L><S><L><V><F><I><F><R><V><L><V><Y><L><V><T><A><E><R><V><W><S><D><D><H><K><D><F><D><C><N><T><R><Q><P><G><C><S><N><V><C><F><D><E><F><F><P><V><S><H><V><R><L><W><A><L><Q><L><I><L><V><T><C><P><S><L><L><V><V><M><H><V><A><Y><R><E><V><Q><E><K><R><H><R><E><A><H><G><E><N><S><G><R><L><Y><L><N><P><G><K><K><R><G><G><L><W><W><T><Y><V><C><S><L><V><F><K><A><S><V><D><I><A><F><L><Y><V><F><H><S><F><Y><P><K><Y><I><L><P><P><V><V><K><C><H><A><D><P><C><P><N><I><V><D><C><F><I><S><K><P><S><E><K><N><I><F><T><L><F><M><V><A><T><A><A><I><C><I><L><L><N><L><V><E><L><I><Y><L><V><S><K><R><C><H><E><C><L><A><A><R><K><A><Q><A><M><C><T><G><H><H><P><H><G><T><T><S><S><C><K><Q><D><D><L><L><S><G><D><L><I><F><L><G><S><D><S><H><P><P><L><L><P><D><R><P><R><D><H><V><K><K><T><I><L>
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.<BOP>
O95377
P33764
S10A3_HUMAN
S100 calcium-binding protein A3
Homo
<M><A><R><P><L><E><Q><A><V><A><A><I><V><C><T><F><Q><E><Y><A><G><R><C><G><D><K><Y><K><L><C><Q><A><E><L><K><E><L><L><Q><K><E><L><A><T><W><T><P><T><E><F><R><E><C><D><Y><N><K><F><M><S><V><L><D><T><N><K><D><C><E><V><D><F><V><E><Y><V><R><S><L><A><C><L><C><L><Y><C><H><E><Y><F><K><D><C><P><S><E><P><P><C><S><Q>
Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.<BOP>
P33764
Q9UJ90
KCNE5_HUMAN
Potassium voltage-gated channel subfamily E member 1-like protein
Homo
<M><N><C><S><E><S><Q><R><L><R><T><L><L><S><R><L><L><L><E><L><H><H><R><G><N><A><S><G><L><G><A><G><P><R><P><S><M><G><M><G><V><V><P><D><P><F><V><G><R><E><V><T><S><A><K><G><D><D><A><Y><L><Y><I><L><L><I><M><I><F><Y><A><C><L><A><G><G><L><I><L><A><Y><T><R><S><R><K><L><V><E><A><K><D><E><P><S><Q><A><C><A><E><H><E><W><A><P><G><G><A><L><T><A><D><A><E><A><A><A><G><S><Q><A><E><G><R><R><Q><L><A><S><E><G><L><P><A><L><A><Q><G><A><E><R><V>
Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.<BOP>
Q9UJ90
P10124
SRGN_HUMAN
Secretory granule proteoglycan core protein
Homo
<M><M><Q><K><L><L><K><C><S><R><L><V><L><A><L><A><L><I><L><V><L><E><S><S><V><Q><G><Y><P><T><R><R><A><R><Y><Q><W><V><R><C><N><P><D><S><N><S><A><N><C><L><E><E><K><G><P><M><F><E><L><L><P><G><E><S><N><K><I><P><R><L><R><T><D><L><F><P><K><T><R><I><Q><D><L><N><R><I><F><P><L><S><E><D><Y><S><G><S><G><F><G><S><G><S><G><S><G><S><G><S><G><S><G><F><L><T><E><M><E><Q><D><Y><Q><L><V><D><E><S><D><A><F><H><D><N><L><R><S><L><D><R><N><L><P><S><D><S><Q><D><L><G><Q><H><G><L><E><E><D><F><M><L>
Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.<BOP>
P10124
P0DML3
CSH2_HUMAN
Placental lactogen
Homo
<M><A><A><G><S><R><T><S><L><L><L><A><F><A><L><L><C><L><P><W><L><Q><E><A><G><A><V><Q><T><V><P><L><S><R><L><F><D><H><A><M><L><Q><A><H><R><A><H><Q><L><A><I><D><T><Y><Q><E><F><E><E><T><Y><I><P><K><D><Q><K><Y><S><F><L><H><D><S><Q><T><S><F><C><F><S><D><S><I><P><T><P><S><N><M><E><E><T><Q><Q><K><S><N><L><E><L><L><R><I><S><L><L><L><I><E><S><W><L><E><P><V><R><F><L><R><S><M><F><A><N><N><L><V><Y><D><T><S><D><S><D><D><Y><H><L><L><K><D><L><E><E><G><I><Q><T><L><M><G><R><L><E><D><G><S><R><R><T><G><Q><I><L><K><Q><T><Y><S><K><F><D><T><N><S><H><N><H><D><A><L><L><K><N><Y><G><L><L><Y><C><F><R><K><D><M><D><K><V><E><T><F><L><R><M><V><Q><C><R><S><V><E><G><S><C><G><F>
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.<BOP>
P0DML3
Q6DN03
H2B2C_HUMAN
Histone H2B.t
Homo
<M><P><E><P><A><K><F><A><P><A><P><K><K><G><S><K><K><A><V><T><K><A><Q><K><K><D><G><K><K><R><K><R><S><R><K><E><S><Y><S><I><Y><V><Y><K><V><L><K><R><V><H><P><D><T><G><I><W><C><K><A><M><G><I><M><N><S><F><L><N><D><I><F><E><R><I><A><G><E><A><S><R><L><A><H><Y><N><K><R><S><T><I><T><S><R><R><S><R><R><P><C><A><C><C><C><P><A><S><W><P><S><T><P><C><P><R><A><P><R><R><S><P><S><T><P><A><P><S><E><S><L><P><G><P><G><A><R><S><L><P><P><S><L><P><P><R><V><A><G><C><F><V><S><K><G><S><F><Q><G><H><L><T><T><S><V><K><E><S><F><L><C><C><Q><S><Q><L><M><F><L><A><S><R><L><V><N><F><R><R><A><H><N><T><K><H><R>
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<BOP>
Q6DN03
P0C7P0
CISD3_HUMAN
Mitochondrial inner NEET protein
Homo
<M><R><G><A><G><A><I><L><R><P><A><A><R><G><A><R><D><L><N><P><R><R><D><I><S><S><W><L><A><Q><W><F><P><R><T><P><A><R><S><V><V><A><L><K><T><P><I><K><V><E><L><V><A><G><K><T><Y><R><W><C><V><C><G><R><S><K><K><Q><P><F><C><D><G><S><H><F><F><Q><R><T><G><L><S><P><L><K><F><K><A><Q><E><T><R><M><V><A><L><C><T><C><K><A><T><Q><R><P><P><Y><C><D><G><T><H><R><S><E><R><V><Q><K><A><E><V><G><S><P><L>
Can transfer its iron-sulfur clusters to the apoferrodoxins FDX1 and FDX2. Contributes to mitochondrial iron homeostasis and in maintaining normal levels of free iron and reactive oxygen species, and thereby contributes to normal mitochondrial function.<BOP>
P0C7P0
Q8IX29
FBX16_HUMAN
F-box only protein 16
Homo
<M><M><A><F><A><P><P><K><N><T><D><G><P><K><M><Q><T><K><M><S><T><W><T><P><L><N><H><Q><L><L><N><D><R><V><F><E><E><R><R><A><L><L><G><K><W><F><D><K><W><T><D><S><Q><R><R><R><I><L><T><G><L><L><E><R><C><S><L><S><Q><Q><K><F><C><C><R><K><L><Q><E><K><I><P><A><E><A><L><D><F><T><T><K><L><P><R><V><L><S><L><Y><I><F><S><F><L><D><P><R><S><L><C><R><C><A><Q><V><C><W><H><W><K><N><L><A><E><L><D><Q><L><W><M><L><K><C><L><R><F><N><W><Y><I><N><F><S><P><T><P><F><E><Q><G><I><W><K><K><H><Y><I><Q><M><V><K><E><L><H><I><T><K><P><K><T><P><P><K><D><G><F><V><I><A><D><V><Q><L><V><T><S><N><S><P><E><E><K><Q><S><P><L><S><A><F><R><S><S><S><S><L><R><K><K><N><N><S><G><E><K><A><L><P><P><W><R><S><S><D><K><H><P><T><D><I><I><R><F><N><Y><L><D><N><R><D><P><M><E><T><V><Q><Q><G><R><R><K><R><N><Q><M><T><P><D><F><S><R><Q><S><H><D><K><K><N><K><L><Q><D><R><T><R><L><R><K><A><Q><S><M><M><S><R><R><N><P><F><P><L><C><P>
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.<BOP>
Q8IX29
O95210
STBD1_HUMAN
Glycophagy cargo receptor STBD1
Homo
<M><G><A><V><W><S><A><L><L><V><G><G><G><L><A><G><A><L><F><V><W><L><L><R><G><G><P><G><D><T><G><K><D><G><D><A><E><Q><E><K><D><A><P><L><G><G><A><A><I><P><G><G><H><Q><S><G><S><S><G><L><S><P><G><P><S><G><Q><E><L><V><T><K><P><E><H><L><Q><E><S><N><G><H><L><I><S><K><T><K><D><L><G><K><L><Q><A><A><S><W><R><L><Q><N><P><S><R><E><V><C><D><N><S><R><E><H><V><P><S><G><Q><F><P><D><T><E><A><P><A><T><S><E><T><S><N><S><R><S><Y><S><E><V><S><R><N><E><S><L><E><S><P><M><G><E><W><G><F><Q><K><G><Q><E><I><S><A><K><A><A><T><C><F><A><E><K><L><P><S><S><N><L><L><K><N><R><A><K><E><E><M><S><L><S><D><L><N><S><Q><D><R><V><D><H><E><E><W><E><M><V><P><R><H><S><S><W><G><D><V><G><V><G><G><S><L><K><A><P><V><L><N><L><N><Q><G><M><D><N><G><R><S><T><L><V><E><A><R><G><Q><Q><V><H><G><K><M><E><R><V><A><V><M><P><A><G><S><Q><Q><V><S><V><R><F><Q><V><H><Y><V><T><S><T><D><V><Q><F><I><A><V><T><G><D><H><E><C><L><G><R><W><N><T><Y><I><P><L><H><Y><N><K><D><G><F><W><S><H><S><I><F><L><P><A><D><T><V><V><E><W><K><F><V><L><V><E><N><G><G><V><T><R><W><E><E><C><S><N><R><F><L><E><T><G><H><E><D><K><V><V><H><A><W><W><G><I><H>
Acts as a cargo receptor for glycogen. Delivers its cargo to an autophagic pathway called glycophagy, resulting in the transport of glycogen to lysosomes.<BOP>
O95210
P56378
ATP68_HUMAN
ATP synthase membrane subunit 6.8PL
Homo
<M><L><Q><S><I><I><K><N><I><W><I><P><M><K><P><Y><Y><T><K><V><Y><Q><E><I><W><I><G><M><G><L><M><G><F><I><V><Y><K><I><R><A><A><D><K><R><S><K><A><L><K><A><S><A><P><A><P><G><H><H>
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). Minor subunit required to maintain the ATP synthase population in the mitochondria .<BOP>
P56378
Q8IWR1
TRI59_HUMAN
Tumor suppressor TSBF-1
Homo
<M><H><N><F><E><E><E><L><T><C><P><I><C><Y><S><I><F><E><D><P><R><V><L><P><C><S><H><T><F><C><R><N><C><L><E><N><I><L><Q><A><S><G><N><F><Y><I><W><R><P><L><R><I><P><L><K><C><P><N><C><R><S><I><T><E><I><A><P><T><G><I><E><S><L><P><V><N><F><A><L><R><A><I><I><E><K><Y><Q><Q><E><D><H><P><D><I><V><T><C><P><E><H><Y><R><Q><P><L><N><V><Y><C><L><L><D><K><K><L><V><C><G><H><C><L><T><I><G><Q><H><H><G><H><P><I><D><D><L><Q><S><A><Y><L><K><E><K><D><T><P><Q><K><L><L><E><Q><L><T><D><T><H><W><T><D><L><T><H><L><I><E><K><L><K><E><Q><K><S><H><S><E><K><M><I><Q><G><D><K><E><A><V><L><Q><Y><F><K><E><L><N><D><T><L><E><Q><K><K><K><S><F><L><T><A><L><C><D><V><G><N><L><I><N><Q><E><Y><T><P><Q><I><E><R><M><K><E><I><R><E><Q><Q><L><E><L><M><A><L><T><I><S><L><Q><E><E><S><P><L><K><F><L><E><K><V><D><D><V><R><Q><H><V><Q><I><L><K><Q><R><P><L><P><E><V><Q><P><V><E><I><Y><P><R><V><S><K><I><L><K><E><E><W><S><R><T><E><I><G><Q><I><K><N><V><L><I><P><K><M><K><I><S><P><K><R><M><S><C><S><W><P><G><K><D><E><K><E><V><E><F><L><K><I><L><N><I><V><V><V><T><L><I><S><V><I><L><M><S><I><L><F><F><N><Q><H><I><I><T><F><L><S><E><I><T><L><I><W><F><S><E><A><S><L><S><V><Y><Q><S><L><S><N><S><L><H><K><V><K><N><I><L><C><H><I><F><Y><L><L><K><E><F><V><W><K><I><V><S><H>
May serve as a multifunctional regulator for innate immune signaling pathways.<BOP>
Q8IWR1
Q9C029
TRIM7_HUMAN
Tripartite motif-containing protein 7
Homo
<M><A><A><V><G><P><R><T><G><P><G><T><G><A><E><A><L><A><L><A><A><E><L><Q><G><E><A><T><C><S><I><C><L><E><L><F><R><E><P><V><S><V><E><C><G><H><S><F><C><R><A><C><I><G><R><C><W><E><R><P><G><A><G><S><V><G><A><A><T><R><A><P><P><F><P><L><P><C><P><Q><C><R><E><P><A><R><P><S><Q><L><R><P><N><R><Q><L><A><A><V><A><T><L><L><R><R><F><S><L><P><A><A><A><P><G><E><H><G><S><Q><A><A><A><A><R><A><A><A><A><R><C><G><Q><H><G><E><P><F><K><L><Y><C><Q><D><D><G><R><A><I><C><V><V><C><D><R><A><R><E><H><R><E><H><A><V><L><P><L><D><E><A><V><Q><E><A><K><E><L><L><E><S><R><L><R><V><L><K><K><E><L><E><D><C><E><V><F><R><S><T><E><K><K><E><S><K><E><L><L><K><Q><M><A><A><E><Q><E><K><V><G><A><E><F><Q><A><L><R><A><F><L><V><E><Q><E><G><R><L><L><G><R><L><E><E><L><S><R><E><V><A><Q><K><Q><N><E><N><L><A><Q><L><G><V><E><I><T><Q><L><S><K><L><S><S><Q><I><Q><E><T><A><Q><K><P><D><L><D><F><L><Q><E><F><K><S><T><L><S><R><C><S><N><V><P><G><P><K><P><T><T><V><S><S><E><M><K><N><K><V><W><N><V><S><L><K><T><F><V><L><K><G><M><L><K><K><F><K><E><D><L><R><G><E><L><E><K><E><E><K><V><E><L><T><L><D><P><D><T><A><N><P><R><L><I><L><S><L><D><L><K><G><V><R><L><G><E><R><A><Q><D><L><P><N><H><P><C><R><F><D><T><N><T><R><V><L><A><S><C><G><F><S><S><G><R><H><H><W><E><V><E><V><G><S><K><D><G><W><A><F><G><V><A><R><E><S><V><R><R><K><G><L><T><P><F><T><P><E><E><G><V><W><A><L><Q><L><N><G><G><Q><Y><W><A><V><T><S><P><E><R><S><P><L><S><C><G><H><L><S><R><V><R><V><A><L><D><L><E><V><G><A><V><S><F><Y><A><V><E><D><M><R><H><L><Y><T><F><R><V><N><F><Q><E><R><V><F><P><L><F><S><V><C><S><T><G><T><Y><L><R><I><W><P>
(Microbial infection) Promotes Zika virus replication by mediating envelope protein E ubiquitination.<BOP>
Q9C029
Q9H3K6
BOLA2_HUMAN
BolA-like protein 2
Homo
<M><E><L><S><A><E><Y><L><R><E><K><L><Q><R><D><L><E><A><E><H><V><E><V><E><D><T><T><L><N><R><C><S><C><S><F><R><V><L><V><V><S><A><K><F><E><G><K><P><L><L><Q><R><H><R><L><V><N><A><C><L><A><E><E><L><P><H><I><H><A><F><E><Q><K><T><L><T><P><D><Q><W><A><R><E><R><Q><K>
Acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins . Acts together with the monothiol glutaredoxin GLRX3 .<BOP>
Q9H3K6
P06681
CO2_HUMAN
Complement C2a fragment
Homo
<M><G><P><L><M><V><L><F><C><L><L><F><L><Y><P><G><L><A><D><S><A><P><S><C><P><Q><N><V><N><I><S><G><G><T><F><T><L><S><H><G><W><A><P><G><S><L><L><T><Y><S><C><P><Q><G><L><Y><P><S><P><A><S><R><L><C><K><S><S><G><Q><W><Q><T><P><G><A><T><R><S><L><S><K><A><V><C><K><P><V><R><C><P><A><P><V><S><F><E><N><G><I><Y><T><P><R><L><G><S><Y><P><V><G><G><N><V><S><F><E><C><E><D><G><F><I><L><R><G><S><P><V><R><Q><C><R><P><N><G><M><W><D><G><E><T><A><V><C><D><N><G><A><G><H><C><P><N><P><G><I><S><L><G><A><V><R><T><G><F><R><F><G><H><G><D><K><V><R><Y><R><C><S><S><N><L><V><L><T><G><S><S><E><R><E><C><Q><G><N><G><V><W><S><G><T><E><P><I><C><R><Q><P><Y><S><Y><D><F><P><E><D><V><A><P><A><L><G><T><S><F><S><H><M><L><G><A><T><N><P><T><Q><K><T><K><E><S><L><G><R><K><I><Q><I><Q><R><S><G><H><L><N><L><Y><L><L><L><D><C><S><Q><S><V><S><E><N><D><F><L><I><F><K><E><S><A><S><L><M><V><D><R><I><F><S><F><E><I><N><V><S><V><A><I><I><T><F><A><S><E><P><K><V><L><M><S><V><L><N><D><N><S><R><D><M><T><E><V><I><S><S><L><E><N><A><N><Y><K><D><H><E><N><G><T><G><T><N><T><Y><A><A><L><N><S><V><Y><L><M><M><N><N><Q><M><R><L><L><G><M><E><T><M><A><W><Q><E><I><R><H><A><I><I><L><L><T><D><G><K><S><N><M><G><G><S><P><K><T><A><V><D><H><I><R><E><I><L><N><I><N><Q><K><R><N><D><Y><L><D><I><Y><A><I><G><V><G><K><L><D><V><D><W><R><E><L><N><E><L><G><S><K><K><D><G><E><R><H><A><F><I><L><Q><D><T><K><A><L><H><Q><V><F><E><H><M><L><D><V><S><K><L><T><D><T><I><C><G><V><G><N><M><S><A><N><A><S><D><Q><E><R><T><P><W><H><V><T><I><K><P><K><S><Q><E><T><C><R><G><A><L><I><S><D><Q><W><V><L><T><A><A><H><C><F><R><D><G><N><D><H><S><L><W><R><V><N><V><G><D><P><K><S><Q><W><G><K><E><F><L><I><E><K><A><V><I><S><P><G><F><D><V><F><A><K><K><N><Q><G><I><L><E><F><Y><G><D><D><I><A><L><L><K><L><A><Q><K><V><K><M><S><T><H><A><R><P><I><C><L><P><C><T><M><E><A><N><L><A><L><R><R><P><Q><G><S><T><C><R><D><H><E><N><E><L><L><N><K><Q><S><V><P><A><H><F><V><A><L><N><G><S><K><L><N><I><N><L><K><M><G><V><E><W><T><S><C><A><E><V><V><S><Q><E><K><T><M><F><P><N><L><T><D><V><R><E><V><V><T><D><Q><F><L><C><S><G><T><Q><E><D><E><S><P><C><K><G><E><S><G><G><A><V><F><L><E><R><R><F><R><F><F><Q><V><G><L><V><S><W><G><L><Y><N><P><C><L><G><S><A><D><K><N><S><R><K><R><A><P><R><S><K><V><P><P><P><R><D><F><H><I><N><L><F><R><M><Q><P><W><L><R><Q><H><L><G><D><V><L><N><F><L><P><L>
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.<BOP>
P06681
Q6V702
CF299_HUMAN
Cilia- and flagella-associated protein 299
Homo
<M><D><Q><E><E><G><L><K><A><L><D><N><I><V><T><Q><F><N><A><Y><E><D><F><L><D><S><Q><I><T><T><V><D><L><Y><Y><L><E><D><E><T><L><A><R><Q><L><V><E><L><G><Y><R><G><T><G><E><R><V><K><R><E><D><F><E><A><R><K><A><A><I><E><I><A><R><L><A><E><R><A><Q><Q><K><T><L><T><S><A><G><K><D><L><Q><D><N><F><L><T><A><L><A><M><R><E><E><D><N><R><S><G><K><L><S><S><V><I><F><I><R><D><R><N><S><H><G><Q><E><I><S><G><Y><I><D><Y><A><H><R><L><K><T><E><D><F><E><V><Y><F><T><G><K><K><R><L><L><P><R><P><T><D><I><S><F><Y><N><W><D><A><D><I><A><V><S><N><S><S><P><N><Y><Q><V><I><A><D><N><P><E><G><L><L><F><R><Y><K><R><D><R><K><I><L><N><V><D><P><K><A><Q><P><G><D><N><S><T><R><I><T><I><L><T><E><L><Y><V><Q><A><V><I><F><D><H><I><S><R><R><K><T>
May be involved in spermatogenesis.<BOP>
Q6V702
Q96S52
PIGS_HUMAN
Phosphatidylinositol-glycan biosynthesis class S protein
Homo
<M><A><A><A><G><A><A><A><T><H><L><E><V><A><R><G><K><R><A><A><L><F><F><A><A><V><A><I><V><L><G><L><P><L><W><W><K><T><T><E><T><Y><R><A><S><L><P><Y><S><Q><I><S><G><L><N><A><L><Q><L><R><L><M><V><P><V><T><V><V><F><T><R><E><S><V><P><L><D><D><Q><E><K><L><P><F><T><V><V><H><E><R><E><I><P><L><K><Y><K><M><K><I><K><C><R><F><Q><K><A><Y><R><R><A><L><D><H><E><E><E><A><L><S><S><G><S><V><Q><E><A><E><A><M><L><D><E><P><Q><E><Q><A><E><G><S><L><T><V><Y><V><I><S><E><H><S><S><L><L><P><Q><D><M><M><S><Y><I><G><P><K><R><T><A><V><V><R><G><I><M><H><R><E><A><F><N><I><I><G><R><R><I><V><Q><V><A><Q><A><M><S><L><T><E><D><V><L><A><A><A><L><A><D><H><L><P><E><D><K><W><S><A><E><K><R><R><P><L><K><S><S><L><G><Y><E><I><T><F><S><L><L><N><P><D><P><K><S><H><D><V><Y><W><D><I><E><G><A><V><R><R><Y><V><Q><P><F><L><N><A><L><G><A><A><G><N><F><S><V><D><S><Q><I><L><Y><Y><A><M><L><G><V><N><P><R><F><D><S><A><S><S><S><Y><Y><L><D><M><H><S><L><P><H><V><I><N><P><V><E><S><R><L><G><S><S><A><A><S><L><Y><P><V><L><N><F><L><L><Y><V><P><E><L><A><H><S><P><L><Y><I><Q><D><K><D><G><A><P><V><A><T><N><A><F><H><S><P><R><W><G><G><I><M><V><Y><N><V><D><S><K><T><Y><N><A><S><V><L><P><V><R><V><E><V><D><M><V><R><V><M><E><V><F><L><A><Q><L><R><L><L><F><G><I><A><Q><P><Q><L><P><P><K><C><L><L><S><G><P><T><S><E><G><L><M><T><W><E><L><D><R><L><L><W><A><R><S><V><E><N><L><A><T><A><T><T><T><L><T><S><L><A><Q><L><L><G><K><I><S><N><I><V><I><K><D><D><V><A><S><E><V><Y><K><A><V><A><A><V><Q><K><S><A><E><E><L><A><S><G><H><L><A><S><A><F><V><A><S><Q><E><A><V><T><S><S><E><L><A><F><F><D><P><S><L><L><H><L><L><Y><F><P><D><D><Q><K><F><A><I><Y><I><P><L><F><L><P><M><A><V><P><I><L><L><S><L><V><K><I><F><L><E><T><R><K><S><W><R><K><P><E><K><T><D>
Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.<BOP>
Q96S52
Q9NUW8
TYDP1_HUMAN
Tyrosyl-DNA phosphodiesterase 1
Homo
<M><S><Q><E><G><D><Y><G><R><W><T><I><S><S><S><D><E><S><E><E><E><K><P><K><P><D><K><P><S><T><S><S><L><L><C><A><R><Q><G><A><A><N><E><P><R><Y><T><C><S><E><A><Q><K><A><A><H><K><R><K><I><S><P><V><K><F><S><N><T><D><S><V><L><P><P><K><R><Q><K><S><G><S><Q><E><D><L><G><W><C><L><S><S><S><D><D><E><L><Q><P><E><M><P><Q><K><Q><A><E><K><V><V><I><K><K><E><K><D><I><S><A><P><N><D><G><T><A><Q><R><T><E><N><H><G><A><P><A><C><H><R><L><K><E><E><E><D><E><Y><E><T><S><G><E><G><Q><D><I><W><D><M><L><D><K><G><N><P><F><Q><F><Y><L><T><R><V><S><G><V><K><P><K><Y><N><S><G><A><L><H><I><K><D><I><L><S><P><L><F><G><T><L><V><S><S><A><Q><F><N><Y><C><F><D><V><D><W><L><V><K><Q><Y><P><P><E><F><R><K><K><P><I><L><L><V><H><G><D><K><R><E><A><K><A><H><L><H><A><Q><A><K><P><Y><E><N><I><S><L><C><Q><A><K><L><D><I><A><F><G><T><H><H><T><K><M><M><L><L><L><Y><E><E><G><L><R><V><V><I><H><T><S><N><L><I><H><A><D><W><H><Q><K><T><Q><G><I><W><L><S><P><L><Y><P><R><I><A><D><G><T><H><K><S><G><E><S><P><T><H><F><K><A><D><L><I><S><Y><L><M><A><Y><N><A><P><S><L><K><E><W><I><D><V><I><H><K><H><D><L><S><E><T><N><V><Y><L><I><G><S><T><P><G><R><F><Q><G><S><Q><K><D><N><W><G><H><F><R><L><K><K><L><L><K><D><H><A><S><S><M><P><N><A><E><S><W><P><V><V><G><Q><F><S><S><V><G><S><L><G><A><D><E><S><K><W><L><C><S><E><F><K><E><S><M><L><T><L><G><K><E><S><K><T><P><G><K><S><S><V><P><L><Y><L><I><Y><P><S><V><E><N><V><R><T><S><L><E><G><Y><P><A><G><G><S><L><P><Y><S><I><Q><T><A><E><K><Q><N><W><L><H><S><Y><F><H><K><W><S><A><E><T><S><G><R><S><N><A><M><P><H><I><K><T><Y><M><R><P><S><P><D><F><S><K><I><A><W><F><L><V><T><S><A><N><L><S><K><A><A><W><G><A><L><E><K><N><G><T><Q><L><M><I><R><S><Y><E><L><G><V><L><F><L><P><S><A><F><G><L><D><S><F><K><V><K><Q><K><F><F><A><G><S><Q><E><P><M><A><T><F><P><V><P><Y><D><L><P><P><E><L><Y><G><S><K><D><R><P><W><I><W><N><I><P><Y><V><K><A><P><D><T><H><G><N><M><W><V><P><S>
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.<BOP>
Q9NUW8
Q9Y692
GMEB1_HUMAN
Parvovirus initiation factor p96
Homo
<M><A><N><A><E><V><S><V><P><V><G><D><V><V><V><V><P><T><E><G><N><E><G><E><N><P><E><D><T><K><T><Q><V><I><L><Q><L><Q><P><V><Q><Q><G><L><F><I><D><G><H><F><Y><N><R><I><Y><E><A><G><S><E><N><N><T><A><V><V><A><V><E><T><H><T><I><H><K><I><E><E><G><I><D><T><G><T><I><E><A><N><E><D><M><E><I><A><Y><P><I><T><C><G><E><S><K><A><I><L><L><W><K><K><F><V><C><P><G><I><N><V><K><C><V><K><F><N><D><Q><L><I><S><P><K><H><F><V><H><L><A><G><K><S><T><L><K><D><W><K><R><A><I><R><L><G><G><I><M><L><R><K><M><M><D><S><G><Q><I><D><F><Y><Q><H><D><K><V><C><S><N><T><C><R><S><T><K><F><D><L><L><I><S><S><A><R><A><P><V><P><G><Q><Q><T><S><V><V><Q><T><P><T><S><A><D><G><S><I><T><Q><I><A><I><S><E><E><S><M><E><E><A><G><L><E><W><N><S><A><L><T><A><A><V><T><M><A><T><E><E><G><V><K><K><D><S><E><E><I><S><E><D><T><L><M><F><W><K><G><I><A><D><V><G><L><M><E><E><V><V><C><N><I><Q><K><E><I><E><E><L><L><R><G><V><Q><Q><R><L><I><Q><A><P><F><Q><V><T><D><A><A><V><L><N><N><V><A><H><T><F><G><L><M><D><T><V><K><K><V><L><D><N><R><R><N><Q><V><E><Q><G><E><E><Q><F><L><Y><T><L><T><D><L><E><R><Q><L><E><E><Q><K><K><Q><G><Q><D><H><R><L><K><S><Q><T><V><Q><N><V><V><L><M><P><V><S><T><P><K><P><P><K><R><P><R><L><Q><R><P><A><S><T><T><V><L><S><P><S><P><P><V><Q><Q><P><Q><F><T><V><I><S><P><I><T><I><T><P><V><G><Q><S><F><S><M><G><N><I><P><V><A><T><L><S><Q><G><S><S><P><V><T><V><H><T><L><P><S><G><P><Q><L><F><R><Y><A><T><V><V><S><S><A><K><S><S><S><P><D><T><V><T><I><H><P><S><S><S><L><A><L><L><S><S><T><A><M><Q><D><G><S><T><L><G><N><M><T><T><M><V><S><P><V><E><L><V><A><M><E><S><G><L><T><S><A><I><Q><A><V><E><S><T><S><E><D><G><Q><T><I><I><E><I><D><P><A><P><D><P><E><A><E><D><T><E><G><K><A><V><I><L><E><T><E><L><R><T><E><E><K><V><V><A><E><M><E><E><H><Q><H><Q><V><H><N><V><E><I><V><V><L><E><D>
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses.<BOP>
Q9Y692
P19652
A1AG2_HUMAN
Orosomucoid-2
Homo
<M><A><L><S><W><V><L><T><V><L><S><L><L><P><L><L><E><A><Q><I><P><L><C><A><N><L><V><P><V><P><I><T><N><A><T><L><D><R><I><T><G><K><W><F><Y><I><A><S><A><F><R><N><E><E><Y><N><K><S><V><Q><E><I><Q><A><T><F><F><Y><F><T><P><N><K><T><E><D><T><I><F><L><R><E><Y><Q><T><R><Q><N><Q><C><F><Y><N><S><S><Y><L><N><V><Q><R><E><N><G><T><V><S><R><Y><E><G><G><R><E><H><V><A><H><L><L><F><L><R><D><T><K><T><L><M><F><G><S><Y><L><D><D><E><K><N><W><G><L><S><F><Y><A><D><K><P><E><T><T><K><E><Q><L><G><E><F><Y><E><A><L><D><C><L><C><I><P><R><S><D><V><M><Y><T><D><W><K><K><D><K><C><E><P><L><E><K><Q><H><E><K><E><R><K><Q><E><E><G><E><S>
Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.<BOP>
P19652
O60645
EXOC3_HUMAN
Exocyst complex component Sec6
Homo
<M><K><E><T><D><R><E><A><V><A><T><A><V><Q><R><V><A><G><M><L><Q><R><P><D><Q><L><D><K><V><E><Q><Y><R><R><R><E><A><R><K><K><A><S><V><E><A><R><L><K><A><A><I><Q><S><Q><L><D><G><V><R><T><G><L><S><Q><L><H><N><A><L><N><D><V><K><D><I><Q><Q><S><L><A><D><V><S><K><D><W><R><Q><S><I><N><T><I><E><S><L><K><D><V><K><D><A><V><V><Q><H><S><Q><L><A><A><A><V><E><N><L><K><N><I><F><S><V><P><E><I><V><R><E><T><Q><D><L><I><E><Q><G><A><L><L><Q><A><H><R><K><L><M><D><L><E><C><S><R><D><G><L><M><Y><E><Q><Y><R><M><D><S><G><N><T><R><D><M><T><L><I><H><G><Y><F><G><S><T><Q><G><L><S><D><E><L><A><K><Q><L><W><M><V><L><Q><R><S><L><V><T><V><R><R><D><P><T><L><L><V><S><V><V><R><I><I><E><R><E><E><K><I><D><R><R><I><L><D><R><K><K><Q><T><G><F><V><P><P><G><R><P><K><N><W><K><E><K><M><F><T><I><L><E><R><T><V><T><T><R><I><E><G><T><Q><A><D><T><R><E><S><D><K><M><W><L><V><R><H><L><E><I><I><R><K><Y><V><L><D><D><L><I><V><A><K><N><L><M><V><Q><C><F><P><P><H><Y><E><I><F><K><N><L><L><N><M><Y><H><Q><A><L><S><T><R><M><Q><D><L><A><S><E><D><L><E><A><N><E><I><V><S><L><L><T><W><V><L><N><T><Y><T><S><T><E><M><M><R><N><V><E><L><A><P><E><V><D><V><G><T><L><E><P><L><L><S><P><H><V><V><S><E><L><L><D><T><Y><M><S><T><L><T><S><N><I><I><A><W><L><R><K><A><L><E><T><D><K><K><D><W><V><K><E><T><E><P><E><A><D><Q><D><G><Y><Y><Q><T><T><L><P><A><I><V><F><Q><M><F><E><Q><N><L><Q><V><A><A><Q><I><S><E><D><L><K><T><K><V><L><V><L><C><L><Q><Q><M><N><S><F><L><S><R><Y><K><D><E><A><Q><L><Y><K><E><E><H><L><R><N><R><Q><H><P><H><C><Y><V><Q><Y><M><I><A><I><I><N><N><C><Q><T><F><K><E><S><I><V><S><L><K><R><K><Y><L><K><N><E><V><E><E><G><V><S><P><S><Q><P><S><M><D><G><I><L><D><A><I><A><K><E><G><C><S><G><L><L><E><E><V><F><L><D><L><E><Q><H><L><N><E><L><M><T><K><K><W><L><L><G><S><N><A><V><D><I><I><C><V><T><V><E><D><Y><F><N><D><F><A><K><I><K><K><P><Y><K><K><R><M><T><A><E><A><H><R><R><V><V><V><E><Y><L><R><A><V><M><Q><K><R><I><S><F><R><S><P><E><E><R><K><E><G><A><E><K><M><V><R><E><A><E><Q><L><R><F><L><F><R><K><L><A><S><G><F><G><E><D><V><D><G><Y><C><D><T><I><V><A><V><A><E><V><I><K><L><T><D><P><S><L><L><Y><L><E><V><S><T><L><V><S><K><Y><P><D><I><R><D><D><H><I><G><A><L><L><A><V><R><G><D><A><S><R><D><M><K><Q><T><I><M><E><T><L><E><Q><G><P><A><Q><A><S><P><S><Y><V><P><L><F><K><D><I><V><V><P><S><L><N><V><A><K><L><L><K>
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.<BOP>
O60645
Q9Y6K9
NEMO_HUMAN
NF-kappa-B essential modifier
Homo
<M><N><R><H><L><W><K><S><Q><L><C><E><M><V><Q><P><S><G><G><P><A><A><D><Q><D><V><L><G><E><E><S><P><L><G><K><P><A><M><L><H><L><P><S><E><Q><G><A><P><E><T><L><Q><R><C><L><E><E><N><Q><E><L><R><D><A><I><R><Q><S><N><Q><I><L><R><E><R><C><E><E><L><L><H><F><Q><A><S><Q><R><E><E><K><E><F><L><M><C><K><F><Q><E><A><R><K><L><V><E><R><L><G><L><E><K><L><D><L><K><R><Q><K><E><Q><A><L><R><E><V><E><H><L><K><R><C><Q><Q><Q><M><A><E><D><K><A><S><V><K><A><Q><V><T><S><L><L><G><E><L><Q><E><S><Q><S><R><L><E><A><A><T><K><E><C><Q><A><L><E><G><R><A><R><A><A><S><E><Q><A><R><Q><L><E><S><E><R><E><A><L><Q><Q><Q><H><S><V><Q><V><D><Q><L><R><M><Q><G><Q><S><V><E><A><A><L><R><M><E><R><Q><A><A><S><E><E><K><R><K><L><A><Q><L><Q><V><A><Y><H><Q><L><F><Q><E><Y><D><N><H><I><K><S><S><V><V><G><S><E><R><K><R><G><M><Q><L><E><D><L><K><Q><Q><L><Q><Q><A><E><E><A><L><V><A><K><Q><E><V><I><D><K><L><K><E><E><A><E><Q><H><K><I><V><M><E><T><V><P><V><L><K><A><Q><A><D><I><Y><K><A><D><F><Q><A><E><R><Q><A><R><E><K><L><A><E><K><K><E><L><L><Q><E><Q><L><E><Q><L><Q><R><E><Y><S><K><L><K><A><S><C><Q><E><S><A><R><I><E><D><M><R><K><R><H><V><E><V><S><Q><A><P><L><P><P><A><P><A><Y><L><S><S><P><L><A><L><P><S><Q><R><R><S><P><P><E><E><P><P><D><F><C><C><P><K><C><Q><Y><Q><A><P><D><M><D><T><L><Q><I><H><V><M><E><C><I><E>
(Microbial infection) Also considered to be a mediator for HTLV-1 Tax oncoprotein activation of NF-kappa-B.<BOP>
Q9Y6K9
Q14588
ZN234_HUMAN
Zinc finger protein HZF4
Homo
<M><T><T><F><K><E><G><L><T><F><K><D><V><A><V><V><F><T><E><E><E><L><G><L><L><D><P><V><Q><R><N><L><Y><Q><D><V><M><L><E><N><F><R><N><L><L><S><V><G><H><H><P><F><K><H><D><V><F><L><L><E><K><E><K><K><L><D><I><M><K><T><A><T><Q><R><K><G><K><S><A><D><K><I><Q><S><E><V><E><T><V><P><E><A><G><R><H><E><E><L><Y><W><G><Q><I><W><K><Q><I><A><S><D><L><I><K><Y><E><D><S><M><I><S><I><S><R><F><P><R><Q><G><D><L><S><C><Q><V><R><A><G><L><Y><T><T><H><T><G><Q><K><F><Y><Q><C><D><E><Y><K><K><S><F><T><D><V><F><N><F><D><L><H><Q><Q><L><H><S><G><E><K><S><H><T><C><D><E><C><G><K><S><F><C><Y><I><S><A><L><H><I><H><Q><R><V><H><M><G><E><K><C><Y><K><C><D><V><C><G><K><E><F><S><Q><S><S><H><L><Q><T><H><Q><R><V><H><T><V><E><K><P><F><K><C><V><E><C><G><K><G><F><S><R><R><S><T><L><T><V><H><C><K><L><H><S><G><E><K><P><Y><N><C><E><E><C><G><R><A><F><I><H><A><S><H><L><Q><E><H><Q><R><I><H><T><G><E><K><P><F><K><C><D><T><C><G><K><N><F><R><R><R><S><A><L><N><N><H><C><M><V><H><T><G><E><K><P><Y><K><C><E><D><C><G><K><C><F><T><C><S><S><N><L><R><I><H><Q><R><V><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><C><F><I><Q><P><S><Q><F><Q><A><H><R><R><I><H><T><G><E><K><P><Y><V><C><K><V><C><G><K><G><F><I><Y><S><S><S><F><Q><A><H><Q><G><V><H><T><G><E><K><P><Y><K><C><N><E><C><G><K><S><F><R><M><K><I><H><Y><Q><V><H><L><V><V><H><T><G><E><K><P><Y><K><C><E><V><C><G><K><A><F><R><Q><S><S><Y><L><K><I><H><L><K><A><H><S><V><Q><K><P><F><K><C><E><E><C><G><Q><G><F><N><Q><S><S><R><L><Q><I><H><Q><L><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><G><F><S><R><R><A><D><L><K><I><H><C><R><I><H><T><G><E><K><P><Y><N><C><E><E><C><G><K><V><F><S><Q><A><S><H><L><L><T><H><Q><R><V><H><S><G><E><K><P><F><K><C><E><E><C><G><K><S><F><S><R><S><A><H><L><Q><A><H><Q><K><V><H><T><G><E><K><P><Y><K><C><G><E><C><G><K><G><F><K><W><S><L><N><L><D><M><H><Q><R><V><H><T><G><E><K><P><Y><T><C><G><E><C><G><K><H><F><S><Q><A><S><S><L><Q><L><H><Q><S><V><H><T><G><E><K><P><Y><K><C><D><V><C><G><K><V><F><S><R><S><S><Q><L><Q><Y><H><R><R><V><H><T><G><E><K><P><Y><K><C><E><I><C><G><K><R><F><S><W><R><S><N><L><V><S><H><H><K><I><H><A><A><G><T><F><Y><E><N><D><E><N><S><K><N><I><R><E><L><S><E><G><G><S><S><T><R>
May be involved in transcriptional regulation.<BOP>
Q14588
Q9UBN1
CCG4_HUMAN
Transmembrane AMPAR regulatory protein gamma-4
Homo
<M><V><R><C><D><R><G><L><Q><M><L><L><T><T><A><G><A><F><A><A><F><S><L><M><A><I><A><I><G><T><D><Y><W><L><Y><S><S><A><H><I><C><N><G><T><N><L><T><M><D><D><G><P><P><P><R><R><A><R><G><D><L><T><H><S><G><L><W><R><V><C><C><I><E><G><I><Y><K><G><H><C><F><R><I><N><H><F><P><E><D><N><D><Y><D><H><D><S><S><E><Y><L><L><R><I><V><R><A><S><S><V><F><P><I><L><S><T><I><L><L><L><L><G><G><L><C><I><G><A><G><R><I><Y><S><R><K><N><N><I><V><L><S><A><G><I><L><F><V><A><A><G><L><S><N><I><I><G><I><I><V><Y><I><S><S><N><T><G><D><P><S><D><K><R><D><E><D><K><K><N><H><Y><N><Y><G><W><S><F><Y><F><G><A><L><S><F><I><V><A><E><T><V><G><V><L><A><V><N><I><Y><I><E><K><N><K><E><L><R><F><K><T><K><R><E><F><L><K><A><S><S><S><S><P><Y><A><R><M><P><S><Y><R><Y><R><R><R><R><S><R><S><S><S><R><S><T><E><A><S><P><S><R><D><V><S><P><M><G><L><K><I><T><G><A><I><P><M><G><E><L><S><M><Y><T><L><S><R><E><P><L><K><V><T><T><A><A><S><Y><S><P><D><Q><E><A><S><F><L><Q><V><H><D><F><F><Q><Q><D><L><K><E><G><F><H><V><S><M><L><N><R><R><T><T><P><V>
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit . Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization .<BOP>
Q9UBN1
Q8NEB7
ACRBP_HUMAN
Acrosin-binding protein, 32 kDa form, mature form
Homo
<M><R><K><P><A><A><G><F><L><P><S><L><L><K><V><L><L><L><P><L><A><P><A><A><A><Q><D><S><T><Q><A><S><T><P><G><S><P><L><S><P><T><E><Y><E><R><F><F><A><L><L><T><P><T><W><K><A><E><T><T><C><R><L><R><A><T><H><G><C><R><N><P><T><L><V><Q><L><D><Q><Y><E><N><H><G><L><V><P><D><G><A><V><C><S><N><L><P><Y><A><S><W><F><E><S><F><C><Q><F><T><H><Y><R><C><S><N><H><V><Y><Y><A><K><R><V><L><C><S><Q><P><V><S><I><L><S><P><N><T><L><K><E><I><E><A><S><A><E><V><S><P><T><T><M><T><S><P><I><S><P><H><F><T><V><T><E><R><Q><T><F><Q><P><W><P><E><R><L><S><N><N><V><E><E><L><L><Q><S><S><L><S><L><G><G><Q><E><Q><A><P><E><H><K><Q><E><Q><G><V><E><H><R><Q><E><P><T><Q><E><H><K><Q><E><E><G><Q><K><Q><E><E><Q><E><E><E><Q><E><E><E><G><K><Q><E><E><G><Q><G><T><K><E><G><R><E><A><V><S><Q><L><Q><T><D><S><E><P><K><F><H><S><E><S><L><S><S><N><P><S><S><F><A><P><R><V><R><E><V><E><S><T><P><M><I><M><E><N><I><Q><E><L><I><R><S><A><Q><E><I><D><E><M><N><E><I><Y><D><E><N><S><Y><W><R><N><Q><N><P><G><S><L><L><Q><L><P><H><T><E><A><L><L><V><L><C><Y><S><I><V><E><N><T><C><I><I><T><P><T><A><K><A><W><K><Y><M><E><E><E><I><L><G><F><G><K><S><V><C><D><S><L><G><R><R><H><M><S><T><C><A><L><C><D><F><C><S><L><K><L><E><Q><C><H><S><E><A><S><L><Q><R><Q><Q><C><D><T><S><H><K><T><P><F><V><S><P><L><L><A><S><Q><S><L><S><I><G><N><Q><V><G><S><P><E><S><G><R><F><Y><G><L><D><L><Y><G><G><L><H><M><D><F><W><C><A><R><L><A><T><K><G><C><E><D><V><R><V><S><G><W><L><Q><T><E><F><L><S><F><Q><D><G><D><F><P><T><K><I><C><D><T><D><Y><I><Q><Y><P><N><Y><C><S><F><K><S><Q><Q><C><L><M><R><N><R><N><R><K><V><S><R><M><R><C><L><Q><N><E><T><Y><S><A><L><S><P><G><K><S><E><D><V><V><L><R><W><S><Q><E><F><S><T><L><T><L><G><Q><F><G>
Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.<BOP>
Q8NEB7
Q9NSA3
CNBP1_HUMAN
Inhibitor of beta-catenin and Tcf-4
Homo
<M><N><R><E><G><A><P><G><K><S><P><E><E><M><Y><I><Q><Q><K><V><R><V><L><L><M><L><R><K><M><G><S><N><L><T><A><S><E><E><E><F><L><R><T><Y><A><G><V><V><N><S><Q><L><S><Q><L><P><P><H><S><I><D><Q><G><A><E><D><V><V><M><A><F><S><R><S><E><T><E><D><R><R><Q>
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.<BOP>
Q9NSA3
P05198
IF2A_HUMAN
Eukaryotic translation initiation factor 2 subunit alpha
Homo
<M><P><G><L><S><C><R><F><Y><Q><H><K><F><P><E><V><E><D><V><V><M><V><N><V><R><S><I><A><E><M><G><A><Y><V><S><L><L><E><Y><N><N><I><E><G><M><I><L><L><S><E><L><S><R><R><R><I><R><S><I><N><K><L><I><R><I><G><R><N><E><C><V><V><V><I><R><V><D><K><E><K><G><Y><I><D><L><S><K><R><R><V><S><P><E><E><A><I><K><C><E><D><K><F><T><K><S><K><T><V><Y><S><I><L><R><H><V><A><E><V><L><E><Y><T><K><D><E><Q><L><E><S><L><F><Q><R><T><A><W><V><F><D><D><K><Y><K><R><P><G><Y><G><A><Y><D><A><F><K><H><A><V><S><D><P><S><I><L><D><S><L><D><L><N><E><D><E><R><E><V><L><I><N><N><I><N><R><R><L><T><P><Q><A><V><K><I><R><A><D><I><E><V><A><C><Y><G><Y><E><G><I><D><A><V><K><E><A><L><R><A><G><L><N><C><S><T><E><N><M><P><I><K><I><N><L><I><A><P><P><R><Y><V><M><T><T><T><T><L><E><R><T><E><G><L><S><V><L><S><Q><A><M><A><V><I><K><E><K><I><E><E><K><R><G><V><F><N><V><Q><M><E><P><K><V><V><T><D><T><D><E><T><E><L><A><R><Q><M><E><R><L><E><R><E><N><A><E><V><D><G><D><D><D><A><E><E><M><E><A><K><A><E><D>
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA . This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex . Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex . In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B . EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF-2-alpha in a global protein synthesis inhibitor, leading to an attenuation of cap-dependent translation, while concomitantly initiating the preferential translation
P05198
Q6UUV9
CRTC1_HUMAN
Transducer of regulated cAMP response element-binding protein 1
Homo
<M><A><T><S><N><N><P><R><K><F><S><E><K><I><A><L><H><N><Q><K><Q><A><E><E><T><A><A><F><E><E><V><M><K><D><L><S><L><T><R><A><A><R><L><Q><L><Q><K><S><Q><Y><L><Q><L><G><P><S><R><G><Q><Y><Y><G><G><S><L><P><N><V><N><Q><I><G><S><G><T><M><D><L><P><F><Q><T><P><F><Q><S><S><G><L><D><T><S><R><T><T><R><H><H><G><L><V><D><R><V><Y><R><E><R><G><R><L><G><S><P><H><R><R><P><L><S><V><D><K><H><G><R><Q><A><D><S><C><P><Y><G><T><M><Y><L><S><P><P><A><D><T><S><W><R><R><T><N><S><D><S><A><L><H><Q><S><T><M><T><P><T><Q><P><E><S><F><S><S><G><S><Q><D><V><H><Q><K><R><V><L><L><L><T><V><P><G><M><E><E><T><T><S><E><A><D><K><N><L><S><K><Q><A><W><D><T><K><K><T><G><S><R><P><K><S><C><E><V><P><G><I><N><I><F><P><S><A><D><Q><E><N><T><T><A><L><I><P><A><T><H><N><T><G><G><S><L><P><D><L><T><N><I><H><F><P><S><P><L><P><T><P><L><D><P><E><E><P><T><F><P><A><L><S><S><S><S><S><T><G><N><L><A><A><N><L><T><H><L><G><I><G><G><A><G><Q><G><M><S><T><P><G><S><S><P><Q><H><R><P><A><G><V><S><P><L><S><L><S><T><E><A><R><R><Q><Q><A><S><P><T><L><S><P><L><S><P><I><T><Q><A><V><A><M><D><A><L><S><L><E><Q><Q><L><P><Y><A><F><F><T><Q><A><G><S><Q><Q><P><P><P><Q><P><Q><P><P><P><P><P><P><P><A><S><Q><Q><P><P><P><P><P><P><P><Q><A><P><V><R><L><P><P><G><G><P><L><L><P><S><A><S><L><T><R><G><P><Q><P><P><P><L><A><V><T><V><P><S><S><L><P><Q><S><P><P><E><N><P><G><Q><P><S><M><G><I><D><I><A><S><A><P><A><L><Q><Q><Y><R><T><S><A><G><S><P><A><N><Q><S><P><T><S><P><V><S><N><Q><G><F><S><P><G><S><S><P><Q><H><T><S><T><L><G><S><V><F><G><D><A><Y><Y><E><Q><Q><M><A><A><R><Q><A><N><A><L><S><H><Q><L><E><Q><F><N><M><M><E><N><A><I><S><S><S><S><L><Y><S><P><G><S><T><L><N><Y><S><Q><A><A><M><M><G><L><T><G><S><H><G><S><L><P><D><S><Q><Q><L><G><Y><A><S><H><S><G><I><P><N><I><I><L><T><V><T><G><E><S><P><P><S><L><S><K><E><L><T><S><S><L><A><G><V><G><D><V><S><F><D><S><D><S><Q><F><P><L><D><E><L><K><I><D><P><L><T><L><D><G><L><H><M><L><N><D><P><D><M><V><L><A><D><P><A><T><E><D><T><F><R><M><D><R><L>
(Microbial infection) Plays a role of coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).<BOP>
Q6UUV9
Q9Y5N5
N6MT1_HUMAN
Protein N(5)-glutamine methyltransferase
Homo
<M><A><G><E><N><F><A><T><P><F><H><G><H><V><G><R><G><A><F><S><D><V><Y><E><P><A><E><D><T><F><L><L><L><D><A><L><E><A><A><A><A><E><L><A><G><V><E><I><C><L><E><V><G><S><G><S><G><V><V><S><A><F><L><A><S><M><I><G><P><Q><A><L><Y><M><C><T><D><I><N><P><E><A><A><A><C><T><L><E><T><A><R><C><N><K><V><H><I><Q><P><V><I><T><D><L><V><K><G><L><L><P><R><L><T><E><K><V><D><L><L><V><F><N><P><P><Y><V><V><T><P><P><Q><E><V><G><S><H><G><I><E><A><A><W><A><G><G><R><N><G><R><E><V><M><D><R><F><F><P><L><V><P><D><L><L><S><P><R><G><L><F><Y><L><V><T><I><K><E><N><N><P><E><E><I><L><K><I><M><K><T><K><G><L><Q><G><T><T><A><L><S><R><Q><A><G><Q><E><T><L><S><V><L><K><F><T><K><S>
Methyltransferase that can methylate proteins and, to a lower extent, arsenic . Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators . Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif . Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated . May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid . It however only plays a limited role in arsenic metabolism compared with AS3MT .<BOP>
Q9Y5N5
Q8IWS0
PHF6_HUMAN
PHD-like zinc finger protein
Homo
<M><S><S><S><V><E><Q><K><K><G><P><T><R><Q><R><K><C><G><F><C><K><S><N><R><D><K><E><C><G><Q><L><L><I><S><E><N><Q><K><V><A><A><H><H><K><C><M><L><F><S><S><A><L><V><S><S><H><S><D><N><E><S><L><G><G><F><S><I><E><D><V><Q><K><E><I><K><R><G><T><K><L><M><C><S><L><C><H><C><P><G><A><T><I><G><C><D><V><K><T><C><H><R><T><Y><H><Y><H><C><A><L><H><D><K><A><Q><I><R><E><K><P><S><Q><G><I><Y><M><V><Y><C><R><K><H><K><K><T><A><H><N><S><E><A><D><L><E><E><S><F><N><E><H><E><L><E><P><S><S><P><K><S><K><K><K><S><R><K><G><R><P><R><K><T><N><F><K><G><L><S><E><D><T><R><S><T><S><S><H><G><T><D><E><M><E><S><S><S><Y><R><D><R><S><P><H><R><S><S><P><S><D><T><R><P><K><C><G><F><C><H><V><G><E><E><E><N><E><A><R><G><K><L><H><I><F><N><A><K><K><A><A><A><H><Y><K><C><M><L><F><S><S><G><T><V><Q><L><T><T><T><S><R><A><E><F><G><D><F><D><I><K><T><V><L><Q><E><I><K><R><G><K><R><M><K><C><T><L><C><S><Q><P><G><A><T><I><G><C><E><I><K><A><C><V><K><T><Y><H><Y><H><C><G><V><Q><D><K><A><K><Y><I><E><N><M><S><R><G><I><Y><K><L><Y><C><K><N><H><S><G><N><D><E><R><D><E><E><D><E><E><R><E><S><K><S><R><G><K><V><E><I><D><Q><Q><Q><L><T><Q><Q><Q><L><N><G><N>
Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<BOP>
Q8IWS0
Q8N9B8
RGF1A_HUMAN
Ras-GEF domain-containing family member 1A
Homo
<M><P><Q><T><S><V><V><F><S><S><I><L><G><P><S><C><S><G><Q><V><Q><P><G><M><G><E><R><G><G><G><A><G><G><G><S><G><D><L><I><F><Q><D><G><H><L><I><S><G><S><L><E><A><L><M><E><H><L><V><P><T><V><D><Y><Y><P><D><R><T><Y><I><F><T><F><L><L><S><S><R><V><F><M><P><P><H><D><L><L><A><R><V><G><Q><I><C><V><E><Q><K><Q><Q><L><E><A><G><P><E><K><A><K><L><K><S><F><S><A><K><I><V><Q><L><L><K><E><W><T><E><A><F><P><Y><D><F><Q><D><E><K><A><M><A><E><L><K><A><I><T><H><R><V><T><Q><C><D><E><E><N><G><T><V><K><K><A><I><A><Q><M><T><Q><S><L><L><L><S><L><A><A><R><S><Q><L><Q><E><L><R><E><K><L><R><P><P><A><V><D><K><G><P><I><L><K><T><K><P><P><A><A><Q><K><D><I><L><G><V><C><C><D><P><L><V><L><A><Q><Q><L><T><H><I><E><L><D><R><V><S><S><I><Y><P><E><D><L><M><Q><I><V><S><H><M><D><S><L><D><N><H><R><C><R><G><D><L><T><K><T><Y><S><L><E><A><Y><D><N><W><F><N><C><L><S><M><L><V><A><T><E><V><C><R><V><V><K><K><K><H><R><T><R><M><L><E><F><F><I><D><V><A><R><E><C><F><N><I><G><N><F><N><S><M><M><A><I><I><S><G><M><N><L><S><P><V><A><R><L><K><K><T><W><S><K><V><K><T><A><K><F><D><V><L><E><H><H><M><D><P><S><S><N><F><C><N><Y><R><T><A><L><Q><G><A><T><Q><R><S><Q><M><A><N><S><S><R><E><K><I><V><I><P><V><F><N><L><F><V><K><D><I><Y><F><L><H><K><I><H><T><N><H><L><P><N><G><H><I><N><F><K><K><F><W><E><I><S><R><Q><I><H><E><F><M><T><W><T><Q><V><E><C><P><F><E><K><D><K><K><I><Q><S><Y><L><L><T><A><P><I><Y><S><E><E><A><L><F><V><A><S><F><E><S><E><G><P><E><N><H><M><E><K><D><S><W><K><T><L><R><T><T><L><L><N><R><A>
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.<BOP>
Q8N9B8
Q96DW6
S2538_HUMAN
Solute carrier family 25 member 38
Homo
<M><I><Q><N><S><R><P><S><L><L><Q><P><Q><D><V><G><D><T><V><E><T><L><M><L><H><P><V><I><K><A><F><L><C><G><S><I><S><G><T><C><S><T><L><L><F><Q><P><L><D><L><L><K><T><R><L><Q><T><L><Q><P><S><D><H><G><S><R><R><V><G><M><L><A><V><L><L><K><V><V><R><T><E><S><L><L><G><L><W><K><G><M><S><P><S><I><V><R><C><V><P><G><V><G><I><Y><F><G><T><L><Y><S><L><K><Q><Y><F><L><R><G><H><P><P><T><A><L><E><S><V><M><L><G><V><G><S><R><S><V><A><G><V><C><M><S><P><I><T><V><I><K><T><R><Y><E><S><G><K><Y><G><Y><E><S><I><Y><A><A><L><R><S><I><Y><H><S><E><G><H><R><G><L><F><S><G><L><T><A><T><L><L><R><D><A><P><F><S><G><I><Y><L><M><F><Y><N><Q><T><K><N><I><V><P><H><D><Q><V><D><A><T><L><I><P><I><T><N><F><S><C><G><I><F><A><G><I><L><A><S><L><V><T><Q><P><A><D><V><I><K><T><H><M><Q><L><Y><P><L><K><F><Q><W><I><G><Q><A><V><T><L><I><F><K><D><Y><G><L><R><G><F><F><Q><G><G><I><P><R><A><L><R><R><T><L><M><A><A><M><A><W><T><V><Y><E><E><M><M><A><K><M><G><L><K><S>
Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.<BOP>
Q96DW6
P47883
OR3A4_HUMAN
Olfactory receptor 3A5
Homo
<M><D><L><G><N><S><G><N><D><S><V><V><T><K><F><V><L><L><G><L><T><E><T><A><A><L><Q><P><I><L><F><V><I><F><L><L><A><Y><V><T><T><I><G><G><T><L><S><I><L><A><A><I><L><M><E><T><K><L><H><S><P><M><Y><F><F><L><G><N><L><S><L><P><D><V><G><C><V><S><V><T><V><P><A><M><L><S><H><F><I><S><N><D><R><S><I><P><Y><K><A><C><L><S><E><L><F><F><F><H><L><L><A><G><A><D><C><F><L><L><T><I><M><A><Y><D><R><Y><L><A><I><C><Q><S><L><T><Y><S><S><R><M><S><W><G><I><Q><Q><A><L><V><G><M><S><C><V><F><S><F><T><N><A><L><T><Q><T><V><A><L><S><P><L><N><F><C><G><P><N><V><I><N><H><F><Y><C><D><L><P><Q><P><F><Q><L><S><C><S><S><V><H><L><N><G><Q><L><L><F><V><A><A><A><F><M><G><V><A><P><L><V><L><I><T><V><S><Y><A><H><V><A><A><A><V><L><R><I><R><S><A><E><G><R><K><K><A><F><S><T><C><S><S><H><L><T><V><V><G><I><F><Y><G><T><G><V><F><S><Y><T><R><L><G><S><V><E><S><S><D><K><D><K><G><I><G><I><L><N><T><V><I><S><P><M><L><N><P><L><I><Y><W><T><S><L><L><D><V><G><C><I><S><H><C><S><S><D><A><G><V><S><P><G><P><P><V><Q><S><S><L><C><C><L><Q><F><T><A><L><L><S><P><P><P><G><W><G><G><L><S><P><L><N><S><H><G><L>
Odorant receptor.<BOP>
P47883
P26718
NKG2D_HUMAN
NKG2-D-activating NK receptor
Homo
<M><G><W><I><R><G><R><R><S><R><H><S><W><E><M><S><E><F><H><N><Y><N><L><D><L><K><K><S><D><F><S><T><R><W><Q><K><Q><R><C><P><V><V><K><S><K><C><R><E><N><A><S><P><F><F><F><C><C><F><I><A><V><A><M><G><I><R><F><I><I><M><V><T><I><W><S><A><V><F><L><N><S><L><F><N><Q><E><V><Q><I><P><L><T><E><S><Y><C><G><P><C><P><K><N><W><I><C><Y><K><N><N><C><Y><Q><F><F><D><E><S><K><N><W><Y><E><S><Q><A><S><C><M><S><Q><N><A><S><L><L><K><V><Y><S><K><E><D><Q><D><L><L><K><L><V><K><S><Y><H><W><M><G><L><V><H><I><P><T><N><G><S><W><Q><W><E><D><G><S><I><L><S><P><N><L><L><T><I><I><E><M><Q><K><G><D><C><A><L><Y><A><S><S><F><K><G><Y><I><E><N><C><S><T><P><N><T><Y><I><C><M><Q><R><T><V>
Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, RAET1L/ULBP6, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.<BOP>
P26718
O60895
RAMP2_HUMAN
Calcitonin-receptor-like receptor activity-modifying protein 2
Homo
<M><A><S><L><R><V><E><R><A><G><G><P><R><L><P><R><T><R><V><G><R><P><A><A><L><R><L><L><L><L><L><G><A><V><L><N><P><H><E><A><L><A><Q><P><L><P><T><T><G><T><P><G><S><E><G><G><T><V><K><N><Y><E><T><A><V><Q><F><C><W><N><H><Y><K><D><Q><M><D><P><I><E><K><D><W><C><D><W><A><M><I><S><R><P><Y><S><T><L><R><D><C><L><E><H><F><A><E><L><F><D><L><G><F><P><N><P><L><A><E><R><I><I><F><E><T><H><Q><I><H><F><A><N><C><S><L><V><Q><P><T><F><S><D><P><P><E><D><V><L><L><A><M><I><I><A><P><I><C><L><I><P><F><L><I><T><L><V><V><W><R><S><K><D><S><E><A><Q><A>
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.<BOP>
O60895
Q8NAF0
ZN579_HUMAN
Zinc finger protein 579
Homo
<M><D><P><Q><P><P><P><P><A><Q><G><S><P><P><H><R><G><R><G><R><G><R><G><R><G><R><G><R><G><R><G><R><G><R><G><G><A><G><A><P><R><A><P><L><P><C><P><T><C><G><R><L><F><R><F><P><Y><Y><L><S><R><H><R><L><S><H><S><G><L><R><P><H><A><C><P><L><C><P><K><A><F><R><R><P><A><H><L><S><R><H><L><R><G><H><G><P><Q><P><P><L><R><C><A><A><C><P><R><T><F><P><E><P><A><Q><L><R><R><H><L><A><Q><E><H><A><G><G><E><V><E><L><A><I><E><R><V><A><K><E><T><A><E><P><S><W><G><P><Q><D><E><G><S><E><P><P><T><T><A><A><A><G><A><T><E><E><E><A><V><A><A><W><P><E><T><W><P><A><G><E><P><S><T><L><A><A><P><T><S><A><A><E><P><R><E><S><E><S><E><E><A><E><A><G><A><A><E><L><R><A><E><L><A><L><A><A><G><R><Q><E><E><K><Q><V><L><L><Q><A><D><W><T><L><L><C><L><R><C><R><E><A><F><A><T><K><G><E><L><K><A><H><P><C><L><R><P><E><G><E><Q><E><G><E><G><G><P><P><P><R><P><K><R><H><Q><C><S><I><C><L><K><A><F><A><R><P><W><S><L><S><R><H><R><L><V><H><S><T><D><R><P><F><V><C><P><D><C><G><L><A><F><R><L><A><S><Y><L><R><Q><H><R><R><V><H><G><P><L><S><L><L><A><P><L><P><A><A><G><K><K><D><D><K><A><S><G><A><R><N><S><A><K><G><P><E><G><G><E><G><A><E><C><G><G><A><S><E><G><G><E><G><Q><N><G><G><D><A><A><P><A><R><P><P><A><G><E><P><R><F><W><C><P><E><C><G><K><G><F><R><R><R><A><H><L><R><Q><H><G><V><T><H><S><G><A><R><P><F><Q><C><V><R><C><Q><R><E><F><K><R><L><A><D><L><A><R><H><A><Q><V><H><A><G><G><P><A><P><H><P><C><P><R><C><P><R><R><F><S><R><A><Y><S><L><L><R><H><Q><R><C><H><R><A><E><L><E><R><A><A><A><L><Q><A><L><Q><A><Q><A><P><T><S><P><P><P><P><P><P><P><L><K><A><E><Q><E><E><E><G><L><P><L><P><L><A><N><I><K><E><E><P><P><S><P><G><T><P><P><Q><S><P><P><A><P><P><V><F><L><S><A><S><C><F><D><S><Q><D><H><S><A><F><E><M><E><E><E><E><V><D><S><K><A><H><L><R><G><L><G><G><L><A><S>
May be involved in transcriptional regulation.<BOP>
Q8NAF0
P54577
SYYC_HUMAN
Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed
Homo
<M><G><D><A><P><S><P><E><E><K><L><H><L><I><T><R><N><L><Q><E><V><L><G><E><E><K><L><K><E><I><L><K><E><R><E><L><K><I><Y><W><G><T><A><T><T><G><K><P><H><V><A><Y><F><V><P><M><S><K><I><A><D><F><L><K><A><G><C><E><V><T><I><L><F><A><D><L><H><A><Y><L><D><N><M><K><A><P><W><E><L><L><E><L><R><V><S><Y><Y><E><N><V><I><K><A><M><L><E><S><I><G><V><P><L><E><K><L><K><F><I><K><G><T><D><Y><Q><L><S><K><E><Y><T><L><D><V><Y><R><L><S><S><V><V><T><Q><H><D><S><K><K><A><G><A><E><V><V><K><Q><V><E><H><P><L><L><S><G><L><L><Y><P><G><L><Q><A><L><D><E><E><Y><L><K><V><D><A><Q><F><G><G><I><D><Q><R><K><I><F><T><F><A><E><K><Y><L><P><A><L><G><Y><S><K><R><V><H><L><M><N><P><M><V><P><G><L><T><G><S><K><M><S><S><S><E><E><E><S><K><I><D><L><L><D><R><K><E><D><V><K><K><K><L><K><K><A><F><C><E><P><G><N><V><E><N><N><G><V><L><S><F><I><K><H><V><L><F><P><L><K><S><E><F><V><I><L><R><D><E><K><W><G><G><N><K><T><Y><T><A><Y><V><D><L><E><K><D><F><A><A><E><V><V><H><P><G><D><L><K><N><S><V><E><V><A><L><N><K><L><L><D><P><I><R><E><K><F><N><T><P><A><L><K><K><L><A><S><A><A><Y><P><D><P><S><K><Q><K><P><M><A><K><G><P><A><K><N><S><E><P><E><E><V><I><P><S><R><L><D><I><R><V><G><K><I><I><T><V><E><K><H><P><D><A><D><S><L><Y><V><E><K><I><D><V><G><E><A><E><P><R><T><V><V><S><G><L><V><Q><F><V><P><K><E><E><L><Q><D><R><L><V><V><V><L><C><N><L><K><P><Q><K><M><R><G><V><E><S><Q><G><M><L><L><C><A><S><I><E><G><I><N><R><Q><V><E><P><L><D><P><P><A><G><S><A><P><G><E><H><V><F><V><K><G><Y><E><K><G><Q><P><D><E><E><L><K><P><K><K><K><V><F><E><K><L><Q><A><D><F><K><I><S><E><E><C><I><A><Q><W><K><Q><T><N><F><M><T><K><L><G><S><I><S><C><K><S><L><K><G><G><N><I><S>
Tyrosine--tRNA ligase that catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) (Probable) . Also acts as a positive regulator of poly-ADP-ribosylation in the nucleus, independently of its tyrosine--tRNA ligase activity . Activity is switched upon resveratrol-binding: resveratrol strongly inhibits the tyrosine--tRNA ligase activity and promotes relocalization to the nucleus, where YARS1 specifically stimulates the poly-ADP-ribosyltransferase activity of PARP1 .<BOP>
P54577
P18859
ATP5J_HUMAN
ATP synthase peripheral stalk subunit F6
Homo
<M><I><L><Q><R><L><F><R><F><S><S><V><I><R><S><A><V><S><V><H><L><R><R><N><I><G><V><T><A><V><A><F><N><K><E><L><D><P><I><Q><K><L><F><V><D><K><I><R><E><Y><K><S><K><R><Q><T><S><G><G><P><V><D><A><S><S><E><Y><Q><Q><E><L><E><R><E><L><F><K><L><K><Q><M><F><G><N><A><D><M><N><T><F><P><T><F><K><F><E><D><P><K><F><E><V><I><E><K><P><Q><A>
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.<BOP>
P18859
P20851
C4BPB_HUMAN
C4b-binding protein beta chain
Homo
<M><F><F><W><C><A><C><C><L><M><V><A><W><R><V><S><A><S><D><A><E><H><C><P><E><L><P><P><V><D><N><S><I><F><V><A><K><E><V><E><G><Q><I><L><G><T><Y><V><C><I><K><G><Y><H><L><V><G><K><K><T><L><F><C><N><A><S><K><E><W><D><N><T><T><T><E><C><R><L><G><H><C><P><D><P><V><L><V><N><G><E><F><S><S><S><G><P><V><N><V><S><D><K><I><T><F><M><C><N><D><H><Y><I><L><K><G><S><N><R><S><Q><C><L><E><D><H><T><W><A><P><P><F><P><I><C><K><S><R><D><C><D><P><P><G><N><P><V><H><G><Y><F><E><G><N><N><F><T><L><G><S><T><I><S><Y><Y><C><E><D><R><Y><Y><L><V><G><V><Q><E><Q><Q><C><V><D><G><E><W><S><S><A><L><P><V><C><K><L><I><Q><E><A><P><K><P><E><C><E><K><A><L><L><A><F><Q><E><S><K><N><L><C><E><A><M><E><N><F><M><Q><Q><L><K><E><S><G><M><T><M><E><E><L><K><Y><S><L><E><L><K><K><A><E><L><K><A><K><L><L>
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.<BOP>
P20851
O43324
MCA3_HUMAN
Multisynthase complex auxiliary component p18
Homo
<M><A><A><A><A><E><L><S><L><L><E><K><S><L><G><L><S><K><G><N><K><Y><S><A><Q><G><E><R><Q><I><P><V><L><Q><T><N><N><G><P><S><L><T><G><L><T><T><I><A><A><H><L><V><K><Q><A><N><K><E><Y><L><L><G><S><T><A><E><E><K><A><I><V><Q><Q><W><L><E><Y><R><V><T><Q><V><D><G><H><S><S><K><N><D><I><H><T><L><L><K><D><L><N><S><Y><L><E><D><K><V><Y><L><T><G><Y><N><F><T><L><A><D><I><L><L><Y><Y><G><L><H><R><F><I><V><D><L><T><V><Q><E><K><E><K><Y><L><N><V><S><R><W><F><C><H><I><Q><H><Y><P><G><I><R><Q><H><L><S><S><V><V><F><I><K><N><R><L><Y><T><N><S><H>
Positive modulator of ATM response to DNA damage.<BOP>
O43324
Q8IUR7
ARMC8_HUMAN
Armadillo repeat-containing protein 8
Homo
<M><A><C><L><L><E><T><P><I><R><M><S><V><L><S><E><V><T><A><S><S><R><H><Y><V><D><R><L><F><D><P><D><P><Q><K><V><L><Q><G><V><I><D><M><K><N><A><V><I><G><N><N><K><Q><K><A><N><L><I><V><L><G><A><V><P><R><L><L><Y><L><L><Q><Q><E><T><S><S><T><E><L><K><T><E><C><A><V><V><L><G><S><L><A><M><G><T><E><N><N><V><K><S><L><L><D><C><H><I><I><P><A><L><L><Q><G><L><L><S><P><D><L><K><F><I><E><A><C><L><R><C><L><R><T><I><F><T><S><P><V><T><P><E><E><L><L><Y><T><D><A><T><V><I><P><H><L><M><A><L><L><S><R><S><R><Y><T><Q><E><Y><I><C><Q><I><F><S><H><C><C><K><G><P><D><H><Q><T><I><L><F><N><H><G><A><V><Q><N><I><A><H><L><L><T><S><L><S><Y><K><V><R><M><Q><A><L><K><C><F><S><V><L><A><F><E><N><P><Q><V><S><M><T><L><V><N><V><L><V><D><G><E><L><L><P><Q><I><F><V><K><M><L><Q><R><D><K><P><I><E><M><Q><L><T><S><A><K><C><L><T><Y><M><C><R><A><G><A><I><R><T><D><D><N><C><I><V><L><K><T><L><P><C><L><V><R><M><C><S><K><E><R><L><L><E><E><R><V><E><G><A><E><T><L><A><Y><L><I><E><P><D><V><E><L><Q><R><I><A><S><I><T><D><H><L><I><A><M><L><A><D><Y><F><K><Y><P><S><S><V><S><A><I><T><D><I><K><R><L><D><H><D><L><K><H><A><H><E><L><R><Q><A><A><F><K><L><Y><A><S><L><G><A><N><D><E><D><I><R><K><K><I><I><E><T><E><N><M><M><D><R><I><V><T><G><L><S><E><S><S><V><K><V><R><L><A><A><V><R><C><L><H><S><L><S><R><S><V><Q><Q><L><R><T><S><F><Q><D><H><A><V><W><K><P><L><M><K><V><L><Q><N><A><P><D><E><I><L><V><V><A><S><S><M><L><C><N><L><L><L><E><F><S><P><S><K><E><P><I><L><E><S><G><A><V><E><L><L><C><G><L><T><Q><S><E><N><P><A><L><R><V><N><G><I><W><A><L><M><N><M><A><F><Q><A><E><Q><K><I><K><A><D><I><L><R><S><L><S><T><E><Q><L><F><R><L><L><S><D><S><D><L><N><V><L><M><K><T><L><G><L><L><R><N><L><L><S><T><R><P><H><I><D><K><I><M><S><T><H><G><K><Q><I><M><Q><A><V><T><L><I><L><E><G><E><H><N><I><E><V><K><E><Q><T><L><C><I><L><A><N><I><A><D><G><T><T><A><K><D><L><I><M><T><N><D><D><I><L><Q><K><I><K><Y><Y><M><G><H><S><H><V><K><L><Q><L><A><A><M><F><C><I><S><N><L><I><W><N><E><E><E><G><S><Q><E><R><Q><D><K><L><R><D><M><G><I><V><D><I><L><H><K><L><S><Q><S><P><D><S><N><L><C><D><K><A><K><M><A><L><Q><Q><Y><L><A>
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.<BOP>
Q8IUR7
Q9HD23
MRS2_HUMAN
MRS2-like protein
Homo
<M><E><C><L><R><S><L><P><C><L><L><P><R><A><M><R><L><P><R><R><T><L><C><A><L><A><L><D><V><T><S><V><G><P><P><V><A><A><C><G><R><R><A><N><L><I><G><R><S><R><A><A><Q><L><C><G><P><D><R><L><R><V><A><G><E><V><H><R><F><R><T><S><D><V><S><Q><A><T><L><A><S><V><A><P><V><F><T><V><T><K><F><D><K><Q><G><N><V><T><S><F><E><R><K><K><T><E><L><Y><Q><E><L><G><L><Q><A><R><D><L><R><F><Q><H><V><M><S><I><T><V><R><N><N><R><I><I><M><R><M><E><Y><L><K><A><V><I><T><P><E><C><L><L><I><L><D><Y><R><N><L><N><L><E><Q><W><L><F><R><E><L><P><S><Q><L><S><G><E><G><Q><L><V><T><Y><P><L><P><F><E><F><R><A><I><E><A><L><L><Q><Y><W><I><N><T><L><Q><G><K><L><S><I><L><Q><P><L><I><L><E><T><L><D><A><L><V><D><P><K><H><S><S><V><D><R><S><K><L><H><I><L><L><Q><N><G><K><S><L><S><E><L><E><T><D><I><K><I><F><K><E><S><I><L><E><I><L><D><E><E><E><L><L><E><E><L><C><V><S><K><W><S><D><P><Q><V><F><E><K><S><S><A><G><I><D><H><A><E><E><M><E><L><L><L><E><N><Y><Y><R><L><A><D><D><L><S><N><A><A><R><E><L><R><V><L><I><D><D><S><Q><S><I><I><F><I><N><L><D><S><H><R><N><V><M><M><R><L><N><L><Q><L><T><M><G><T><F><S><L><S><L><F><G><L><M><G><V><A><F><G><M><N><L><E><S><S><L><E><E><D><H><R><I><F><W><L><I><T><G><I><M><F><M><G><S><G><L><I><W><R><R><L><L><S><F><L><G><R><Q><L><E><A><P><L><P><P><M><M><A><S><L><P><K><K><T><L><L><A><D><R><S><M><E><L><K><N><S><L><R><L><D><G><L><G><S><G><R><S><I><L><T><N><R>
Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix . Required for normal expression of the mitochondrial respiratory complex I subunits .<BOP>
Q9HD23
P35625
TIMP3_HUMAN
Tissue inhibitor of metalloproteinases 3
Homo
<M><T><P><W><L><G><L><I><V><L><L><G><S><W><S><L><G><D><W><G><A><E><A><C><T><C><S><P><S><H><P><Q><D><A><F><C><N><S><D><I><V><I><R><A><K><V><V><G><K><K><L><V><K><E><G><P><F><G><T><L><V><Y><T><I><K><Q><M><K><M><Y><R><G><F><T><K><M><P><H><V><Q><Y><I><H><T><E><A><S><E><S><L><C><G><L><K><L><E><V><N><K><Y><Q><Y><L><L><T><G><R><V><Y><D><G><K><M><Y><T><G><L><C><N><F><V><E><R><W><D><Q><L><T><L><S><Q><R><K><G><L><N><Y><R><Y><H><L><G><C><N><C><K><I><K><S><C><Y><Y><L><P><C><F><V><T><S><K><N><E><C><L><W><T><D><M><L><S><N><F><G><Y><P><G><Y><Q><S><K><H><Y><A><C><I><R><Q><K><G><G><Y><C><S><W><Y><R><G><W><A><P><P><D><K><S><I><I><N><A><T><D><P>
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.<BOP>
P35625
Q9Y5U5
TNR18_HUMAN
Glucocorticoid-induced TNFR-related protein
Homo
<M><A><Q><H><G><A><M><G><A><F><R><A><L><C><G><L><A><L><L><C><A><L><S><L><G><Q><R><P><T><G><G><P><G><C><G><P><G><R><L><L><L><G><T><G><T><D><A><R><C><C><R><V><H><T><T><R><C><C><R><D><Y><P><G><E><E><C><C><S><E><W><D><C><M><C><V><Q><P><E><F><H><C><G><D><P><C><C><T><T><C><R><H><H><P><C><P><P><G><Q><G><V><Q><S><Q><G><K><F><S><F><G><F><Q><C><I><D><C><A><S><G><T><F><S><G><G><H><E><G><H><C><K><P><W><T><D><C><T><Q><F><G><F><L><T><V><F><P><G><N><K><T><H><N><A><V><C><V><P><G><S><P><P><A><E><P><L><G><W><L><T><V><V><L><L><A><V><A><A><C><V><L><L><L><T><S><A><Q><L><G><L><H><I><W><Q><L><R><S><Q><C><M><W><P><R><E><T><Q><L><L><L><E><V><P><P><S><T><E><D><A><R><S><C><Q><F><P><E><E><E><R><G><E><R><S><A><E><E><K><G><R><L><G><D><L><W><V>
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.<BOP>
Q9Y5U5
P52788
SPSY_HUMAN
Spermidine aminopropyltransferase
Homo
<M><A><A><A><R><H><S><T><L><D><F><M><L><G><A><K><A><D><G><E><T><I><L><K><G><L><Q><S><I><F><Q><E><Q><G><M><A><E><S><V><H><T><W><Q><D><H><G><Y><L><A><T><Y><T><N><K><N><G><S><F><A><N><L><R><I><Y><P><H><G><L><V><L><L><D><L><Q><S><Y><D><G><D><A><Q><G><K><E><E><I><D><S><I><L><N><K><V><E><E><R><M><K><E><L><S><Q><D><S><T><G><R><V><K><R><L><P><P><I><V><R><G><G><A><I><D><R><Y><W><P><T><A><D><G><R><L><V><E><Y><D><I><D><E><V><V><Y><D><E><D><S><P><Y><Q><N><I><K><I><L><H><S><K><Q><F><G><N><I><L><I><L><S><G><D><V><N><L><A><E><S><D><L><A><Y><T><R><A><I><M><G><S><G><K><E><D><Y><T><G><K><D><V><L><I><L><G><G><G><D><G><G><I><L><C><E><I><V><K><L><K><P><K><M><V><T><M><V><E><I><D><Q><M><V><I><D><G><C><K><K><Y><M><R><K><T><C><G><D><V><L><D><N><L><K><G><D><C><Y><Q><V><L><I><E><D><C><I><P><V><L><K><R><Y><A><K><E><G><R><E><F><D><Y><V><I><N><D><L><T><A><V><P><I><S><T><S><P><E><E><D><S><T><W><E><F><L><R><L><I><L><D><L><S><M><K><V><L><K><Q><D><G><K><Y><F><T><Q><G><N><C><V><N><L><T><E><A><L><S><L><Y><E><E><Q><L><G><R><L><Y><C><P><V><E><F><S><K><E><I><V><C><V><P><S><Y><L><E><L><W><V><F><Y><T><V><W><K><K><A><K><P>
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).<BOP>
P52788
O95047
OR2A4_HUMAN
Olfactory receptor OR6-37
Homo
<M><G><D><N><I><T><S><I><R><E><F><L><L><L><G><F><P><V><G><P><R><I><Q><M><L><L><F><G><L><F><S><L><F><Y><V><F><T><L><L><G><N><G><T><I><L><G><L><I><S><L><D><S><R><L><H><A><P><M><Y><F><F><L><S><H><L><A><V><V><D><I><A><Y><A><C><N><T><V><P><R><M><L><V><N><L><L><H><P><A><K><P><I><S><F><A><G><R><M><M><Q><T><F><L><F><S><T><F><A><V><T><E><C><L><L><L><V><V><M><S><Y><D><L><Y><V><A><I><C><H><P><L><R><Y><L><A><I><M><T><W><R><V><C><I><T><L><A><V><T><S><W><T><T><G><V><L><L><S><L><I><H><L><V><L><L><L><P><L><P><F><C><R><P><Q><K><I><Y><H><F><F><C><E><I><L><A><V><L><K><L><A><C><A><D><T><H><I><N><E><N><M><V><L><A><G><A><I><S><G><L><V><G><P><L><S><T><I><V><V><S><Y><M><C><I><L><C><A><I><L><Q><I><Q><S><R><E><V><Q><R><K><A><F><R><T><C><F><S><H><L><C><V><I><G><L><V><Y><G><T><A><I><I><M><Y><V><G><P><R><Y><G><N><P><K><E><Q><K><K><Y><L><L><L><F><H><S><L><F><N><P><M><L><N><P><L><I><C><S><L><R><N><S><E><V><K><N><T><L><K><R><V><L><G><V><E><R><A><L>
Odorant receptor.<BOP>
O95047
P13500
CCL2_HUMAN
Small-inducible cytokine A2
Homo
<M><K><V><S><A><A><L><L><C><L><L><L><I><A><A><T><F><I><P><Q><G><L><A><Q><P><D><A><I><N><A><P><V><T><C><C><Y><N><F><T><N><R><K><I><S><V><Q><R><L><A><S><Y><R><R><I><T><S><S><K><C><P><K><E><A><V><I><F><K><T><I><V><A><K><E><I><C><A><D><P><K><Q><K><W><V><Q><D><S><M><D><H><L><D><K><Q><T><Q><T><P><K><T>
Acts as a ligand for C-C chemokine receptor CCR2 . Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions . Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils . May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis .<BOP>
P13500
Q96G74
OTUD5_HUMAN
Deubiquitinating enzyme A
Homo
<M><T><I><L><P><K><K><K><P><P><P><P><D><A><D><P><A><N><E><P><P><P><P><G><P><M><P><P><A><P><R><R><G><G><G><V><G><V><G><G><G><G><T><G><V><G><G><G><D><R><D><R><D><S><G><V><V><G><A><R><P><R><A><S><P><P><P><Q><G><P><L><P><G><P><P><G><A><L><H><R><W><A><L><A><V><P><P><G><A><V><A><G><P><R><P><Q><Q><A><S><P><P><P><C><G><G><P><G><G><P><G><G><G><P><G><D><A><L><G><A><A><A><A><G><V><G><A><A><G><V><V><V><G><V><G><G><A><V><G><V><G><G><C><C><S><G><P><G><H><S><K><R><R><R><Q><A><P><G><V><G><A><V><G><G><G><S><P><E><R><E><E><V><G><A><G><Y><N><S><E><D><E><Y><E><A><A><A><A><R><I><E><A><M><D><P><A><T><V><E><Q><Q><E><H><W><F><E><K><A><L><R><D><K><K><G><F><I><I><K><Q><M><K><E><D><G><A><C><L><F><R><A><V><A><D><Q><V><Y><G><D><Q><D><M><H><E><V><V><R><K><H><C><M><D><Y><L><M><K><N><A><D><Y><F><S><N><Y><V><T><E><D><F><T><T><Y><I><N><R><K><R><K><N><N><C><H><G><N><H><I><E><M><Q><A><M><A><E><M><Y><N><R><P><V><E><V><Y><Q><Y><S><T><G><T><S><A><V><E><P><I><N><T><F><H><G><I><H><Q><N><E><D><E><P><I><R><V><S><Y><H><R><N><I><H><Y><N><S><V><V><N><P><N><K><A><T><I><G><V><G><L><G><L><P><S><F><K><P><G><F><A><E><Q><S><L><M><K><N><A><I><K><T><S><E><E><S><W><I><E><Q><Q><M><L><E><D><K><K><R><A><T><D><W><E><A><T><N><E><A><I><E><E><Q><V><A><R><E><S><Y><L><Q><W><L><R><D><Q><E><K><Q><A><R><Q><V><R><G><P><S><Q><P><R><K><A><S><A><T><C><S><S><A><T><A><A><A><S><S><G><L><E><E><W><T><S><R><S><P><R><Q><R><S><S><A><S><S><P><E><H><P><E><L><H><A><E><L><G><M><K><P><P><S><P><G><T><V><L><A><L><A><K><P><P><S><P><C><A><P><G><T><S><S><Q><F><S><A><G><A><D><R><A><T><S><P><L><V><S><L><Y><P><A><L><E><C><R><A><L><I><Q><Q><M><S><P><S><A><F><G><L><N><D><W><D><D><D><E><I><L><A><S><V><L><A><V><S><Q><Q><E><Y><L><D><S><M><K><K><N><K><V><H><R><D><P><P><P><D><K><S>
Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro). Controls neuroectodermal differentiation through cleaving 'Lys-48'-linked ubiquitin chains to counteract degradation of select chromatin regulators such as ARID1A, HDAC2 and HCF1 .<BOP>
Q96G74
Q5SNT2
TM201_HUMAN
Spindle-associated membrane protein 1
Homo
<M><E><G><V><S><A><L><L><A><R><C><P><T><A><G><L><A><G><G><L><G><V><T><A><C><A><A><A><G><V><L><L><Y><R><I><A><R><R><M><K><P><T><H><T><M><V><N><C><W><F><C><N><Q><D><T><L><V><P><Y><G><N><R><N><C><W><D><C><P><H><C><E><Q><Y><N><G><F><Q><E><N><G><D><Y><N><K><P><I><P><A><Q><Y><L><E><H><L><N><H><V><V><S><S><A><P><S><L><R><D><P><S><Q><P><Q><Q><W><V><S><S><Q><V><L><L><C><K><R><C><N><H><H><Q><T><T><K><I><K><Q><L><A><A><F><A><P><R><E><E><G><R><Y><D><E><E><V><E><V><Y><R><H><H><L><E><Q><M><Y><K><L><C><R><P><C><Q><A><A><V><E><Y><Y><I><K><H><Q><N><R><Q><L><R><A><L><L><L><S><H><Q><F><K><R><R><E><A><D><Q><T><H><A><Q><N><F><S><S><A><V><K><S><P><V><Q><V><I><L><L><R><A><L><A><F><L><A><C><A><F><L><L><T><T><A><L><Y><G><A><S><G><H><F><A><P><G><T><T><V><P><L><A><L><P><P><G><G><N><G><S><A><T><P><D><N><G><T><T><P><G><A><E><G><W><R><Q><L><L><G><L><L><P><E><H><M><A><E><K><L><C><E><A><W><A><F><G><Q><S><H><Q><T><G><V><V><A><L><G><L><L><T><C><L><L><A><M><L><L><A><G><R><I><R><L><R><R><I><D><A><F><C><T><C><L><W><A><L><L><L><G><L><H><L><A><E><Q><H><L><Q><A><A><S><P><S><W><L><D><T><L><K><F><S><T><T><S><L><C><C><L><V><G><F><T><A><A><V><A><T><R><K><A><T><G><P><R><R><F><R><P><R><R><F><F><P><G><D><S><A><G><L><F><P><T><S><P><S><L><A><I><P><H><P><S><V><G><G><S><P><A><S><L><F><I><P><S><P><P><S><F><L><P><L><A><N><Q><Q><L><F><R><S><P><R><R><T><S><P><S><S><L><P><G><R><L><S><R><A><L><S><L><G><T><I><P><S><L><T><R><A><D><S><G><Y><L><F><S><G><S><R><P><P><S><Q><V><S><R><S><G><E><F><P><V><S><D><Y><F><S><L><L><S><G><S><C><P><S><S><P><L><P><S><P><A><P><S><V><A><G><S><V><A><S><S><S><G><S><L><R><H><R><R><P><L><I><S><P><A><R><L><N><L><K><G><Q><K><L><L><L><F><P><S><P><P><G><E><A><P><T><T><P><S><S><S><D><E><H><S><P><H><N><G><S><L><F><T><M><E><P><P><H><V><P><R><K><P><P><L><Q><D><V><K><H><A><L><D><L><R><S><K><L><E><R><G><S><A><C><S><N><R><S><I><K><K><E><D><D><S><S><Q><S><S><T><C><V><V><D><T><T><T><R><G><C><S><E><E><A><A><T><W><R><G><R><F><G><P><S><L><V><R><G><L><L><A><V><S><L><A><A><N><A><L><F><T><S><V><F><L><Y><Q><S><L><R>
May define a distinct membrane domain in the vicinity of the mitotic spindle . Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina .<BOP>
Q5SNT2
O00237
RN103_HUMAN
Zinc finger protein 103 homolog
Homo
<M><W><L><K><L><F><F><L><L><L><Y><F><L><V><L><F><V><L><A><R><F><F><E><A><I><V><W><Y><E><T><G><I><F><A><T><Q><L><V><D><P><V><A><L><S><F><K><K><L><K><T><I><L><E><C><R><G><L><G><Y><S><G><L><P><E><K><K><D><V><R><E><L><V><E><K><S><G><D><L><M><E><G><E><L><Y><S><A><L><K><E><E><E><A><S><E><S><V><S><S><T><N><F><S><G><E><M><H><F><Y><E><L><V><E><D><T><K><D><G><I><W><L><V><Q><V><I><A><N><D><R><S><P><L><V><G><K><I><H><W><E><K><M><V><K><K><V><S><R><F><G><I><R><T><G><T><F><N><C><S><S><D><P><R><Y><C><R><R><R><G><W><V><R><S><T><L><I><M><S><V><P><Q><T><S><T><S><K><G><K><V><M><L><K><E><Y><S><G><R><K><I><E><V><E><H><I><F><K><W><I><T><A><H><A><A><S><R><I><K><T><I><Y><N><A><E><H><L><K><E><E><W><N><K><S><D><Q><Y><W><L><K><I><Y><L><F><A><N><L><D><Q><P><P><A><F><F><S><A><L><S><I><K><F><T><G><R><V><E><F><I><F><V><N><V><E><N><W><D><N><K><S><Y><M><T><D><I><G><I><Y><N><M><P><S><Y><I><L><R><T><P><E><G><I><Y><R><Y><G><N><H><T><G><E><F><I><S><L><Q><A><M><D><S><F><L><R><S><L><Q><P><E><V><N><D><L><F><V><L><S><L><V><L><V><N><L><M><A><W><M><D><L><F><I><T><Q><G><A><T><I><K><R><F><V><V><L><I><S><T><L><G><T><Y><N><S><L><L><I><I><S><W><L><P><V><L><G><F><L><Q><L><P><Y><L><D><S><F><Y><E><Y><S><L><K><L><L><R><Y><S><N><T><T><T><L><A><S><W><V><R><A><D><W><M><F><Y><S><S><H><P><A><L><F><L><S><T><Y><L><G><H><G><L><L><I><D><Y><F><E><K><K><R><R><R><N><N><N><N><D><E><V><N><A><N><N><L><E><W><L><S><S><L><W><D><W><Y><T><S><Y><L><F><H><P><I><A><S><F><Q><N><F><P><V><E><S><D><W><D><E><D><P><D><L><F><L><E><R><L><A><F><P><D><L><W><L><H><P><L><I><P><T><D><Y><I><K><N><L><P><M><W><R><F><K><C><L><G><V><Q><S><E><E><E><M><S><E><G><S><Q><D><T><E><N><D><S><E><S><E><N><T><D><T><L><S><S><E><K><E><V><F><E><D><K><Q><S><V><L><H><N><S><P><G><T><A><S><H><C><D><A><E><A><C><S><C><A><N><K><Y><C><Q><T><S><P><C><E><R><K><G><R><S><Y><G><S><Y><N><T><N><E><D><M><E><P><D><W><L><T><W><P><A><D><M><L><H><C><T><E><C><V><V><C><L><E><N><F><E><N><G><C><L><L><M><G><L><P><C><G><H><V><F><H><Q><N><C><I><V><M><W><L><A><G><G><R><H><C><C><P><V><C><R><W><P><S><Y><K><K><K><Q><P><Y><A><Q><H><Q><P><L><S><N><D><V><P><S>
Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.<BOP>
O00237
Q8NGB8
O4F15_HUMAN
Olfactory receptor OR15-14
Homo
<M><N><G><M><N><H><S><V><V><S><E><F><V><F><M><G><L><T><N><S><R><E><I><Q><L><L><L><F><V><F><S><L><L><F><Y><F><A><S><M><M><G><N><L><V><I><V><F><T><V><T><M><D><A><H><L><H><S><P><M><Y><F><L><L><A><N><L><S><I><I><D><M><A><F><C><S><I><T><A><P><K><M><I><C><D><I><F><K><K><H><K><A><I><S><F><R><G><C><I><T><Q><I><F><F><S><H><A><L><G><G><T><E><M><V><L><L><I><A><M><A><F><D><R><Y><M><A><I><C><K><P><L><H><Y><L><T><I><M><S><P><R><M><C><L><Y><F><L><A><T><S><S><I><I><G><L><I><H><S><L><V><Q><L><V><F><V><V><D><L><P><F><C><G><P><N><I><F><D><S><F><Y><C><D><L><P><R><L><L><R><L><A><C><T><N><T><Q><E><L><E><F><M><V><T><V><N><S><G><L><I><S><V><G><S><F><V><L><L><V><I><S><Y><I><F><I><L><F><T><V><W><K><H><S><S><G><G><L><A><K><A><L><S><T><L><S><A><H><V><T><V><V><I><L><F><F><G><P><L><M><F><F><Y><T><W><P><S><P><T><S><H><L><D><K><Y><L><A><I><F><D><A><F><I><T><P><F><L><N><P><V><I><Y><T><F><R><N><K><D><M><K><V><A><M><R><R><L><C><S><R><L><A><H><F><T><K><I><L>
Odorant receptor.<BOP>
Q8NGB8
Q8IV48
ERI1_HUMAN
Protein 3'hExo
Homo
<M><E><D><P><Q><S><K><E><P><A><G><E><A><V><A><L><A><L><L><E><S><P><R><P><E><G><G><E><E><P><P><R><P><S><P><E><E><T><Q><Q><C><K><F><D><G><Q><E><T><K><G><S><K><F><I><T><S><S><A><S><D><F><S><D><P><V><Y><K><E><I><A><I><T><N><G><C><I><N><R><M><S><K><E><E><L><R><A><K><L><S><E><F><K><L><E><T><R><G><V><K><D><V><L><K><K><R><L><K><N><Y><Y><K><K><Q><K><L><M><L><K><E><S><N><F><A><D><S><Y><Y><D><Y><I><C><I><I><D><F><E><A><T><C><E><E><G><N><P><P><E><F><V><H><E><I><I><E><F><P><V><V><L><L><N><T><H><T><L><E><I><E><D><T><F><Q><Q><Y><V><R><P><E><I><N><T><Q><L><S><D><F><C><I><S><L><T><G><I><T><Q><D><Q><V><D><R><A><D><T><F><P><Q><V><L><K><K><V><I><D><W><M><K><L><K><E><L><G><T><K><Y><K><Y><S><L><L><T><D><G><S><W><D><M><S><K><F><L><N><I><Q><C><Q><L><S><R><L><K><Y><P><P><F><A><K><K><W><I><N><I><R><K><S><Y><G><N><F><Y><K><V><P><R><S><Q><T><K><L><T><I><M><L><E><K><L><G><M><D><Y><D><G><R><P><H><C><G><L><D><D><S><K><N><I><A><R><I><A><V><R><M><L><Q><D><G><C><E><L><R><I><N><E><K><M><H><A><G><Q><L><M><S><V><S><S><S><L><P><I><E><G><T><P><P><P><Q><M><P><H><F><R><K>
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.<BOP>
Q8IV48
Q6S5L8
SHC4_HUMAN
Src homology 2 domain-containing-transforming protein C4
Homo
<M><R><E><R><G><Q><D><S><L><A><G><L><V><L><Y><V><G><L><F><G><H><P><G><M><L><H><R><A><K><Y><S><R><F><R><N><E><S><I><T><S><L><D><E><G><S><S><G><G><S><V><G><N><K><G><S><P><Q><P><P><H><P><A><L><A><P><H><L><P><T><E><D><A><T><L><P><S><Q><E><S><P><T><P><L><C><T><L><I><P><R><M><A><S><M><K><L><A><N><P><A><T><L><L><S><L><K><N><F><C><L><G><T><K><E><V><P><R><L><K><L><Q><E><S><R><D><P><G><S><S><G><P><S><S><P><E><T><S><L><S><R><S><G><T><A><P><P><P><Q><Q><D><L><V><G><H><R><A><T><A><L><T><P><D><S><C><P><L><P><G><P><G><E><P><T><L><R><S><R><Q><D><R><H><F><L><Q><H><L><L><G><M><G><M><N><Y><C><V><R><Y><M><G><C><V><E><V><L><Q><S><M><R><S><L><D><F><G><M><R><T><Q><V><T><R><E><A><I><S><R><L><C><E><A><V><P><G><A><N><G><A><I><K><K><R><K><P><P><V><K><F><L><S><T><V><L><G><K><S><N><L><Q><F><S><G><M><N><I><K><L><T><I><S><T><C><S><L><T><L><M><N><L><D><N><Q><Q><I><I><A><N><H><H><M><Q><S><I><S><F><A><S><G><G><D><P><D><T><T><D><Y><V><A><Y><V><A><K><D><P><V><N><Q><R><A><C><H><I><L><E><C><H><N><G><M><A><Q><D><V><I><S><T><I><G><Q><A><F><E><L><R><F><K><Q><Y><L><K><N><P><S><L><N><T><S><C><E><S><E><E><V><H><I><D><S><H><A><E><E><R><E><D><H><E><Y><Y><N><E><I><P><G><K><Q><P><P><V><G><G><V><S><D><M><R><I><K><V><Q><A><T><E><Q><M><A><Y><C><P><I><Q><C><E><K><L><C><Y><L><P><G><N><S><K><C><S><S><V><Y><E><N><C><L><E><Q><S><R><A><I><G><N><V><H><P><R><G><V><Q><S><Q><R><D><T><S><L><L><K><H><T><C><R><V><D><L><F><D><D><P><C><Y><I><N><T><Q><A><L><Q><S><T><P><G><S><A><G><N><Q><R><S><A><Q><P><L><G><S><P><W><H><C><G><K><A><P><E><T><V><Q><P><G><A><T><A><Q><P><A><S><S><H><S><L><P><H><I><K><Q><Q><L><W><S><E><E><C><Y><H><G><K><L><S><R><K><A><A><E><S><L><L><V><K><D><G><D><F><L><V><R><E><S><A><T><S><P><G><Q><Y><V><L><S><G><L><Q><G><G><Q><A><K><H><L><L><L><V><D><P><E><G><K><V><R><T><K><D><H><V><F><D><N><V><G><H><L><I><R><Y><H><M><D><N><S><L><P><I><I><S><S><G><S><E><V><S><L><K><Q><P><V><R><K><D><N><N><P><A><L><L><H><S><N><K>
Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.<BOP>
Q6S5L8
O60831
PRAF2_HUMAN
PRA1 family protein 2
Homo
<M><S><E><V><R><L><P><P><L><R><A><L><D><D><F><V><L><G><S><A><R><L><A><A><P><D><P><C><D><P><Q><R><W><C><H><R><V><I><N><N><L><L><Y><Y><Q><T><N><Y><L><L><C><F><G><I><G><L><A><L><A><G><Y><V><R><P><L><H><T><L><L><S><A><L><V><V><A><V><A><L><G><V><L><V><W><A><A><E><T><R><A><A><V><R><R><C><R><R><S><H><P><A><A><C><L><A><A><V><L><A><V><G><L><L><V><L><W><V><A><G><G><A><C><T><F><L><F><S><I><A><G><P><V><L><L><I><L><V><H><A><S><L><R><L><R><N><L><K><N><K><I><E><N><K><I><E><S><I><G><L><K><R><T><P><M><G><L><L><L><E><A><L><G><Q><E><Q><E><A><G><S>
May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis.<BOP>
O60831
Q9GZS0
DNAI2_HUMAN
Axonemal dynein intermediate chain 2
Homo
<M><E><I><V><Y><V><Y><V><K><K><R><S><E><F><G><K><Q><C><N><F><S><D><R><Q><A><E><L><N><I><D><I><M><P><N><P><E><L><A><E><Q><F><V><E><R><N><P><V><D><T><G><I><Q><C><S><I><S><M><S><E><H><E><A><N><S><E><R><F><E><M><E><T><R><G><V><N><H><V><E><G><G><W><P><K><D><V><N><P><L><E><L><E><Q><T><I><R><F><R><K><K><V><E><K><D><E><N><Y><V><N><A><I><M><Q><L><G><S><I><M><E><H><C><I><K><Q><N><N><A><I><D><I><Y><E><E><Y><F><N><D><E><E><A><M><E><V><M><E><E><D><P><S><A><K><T><I><N><V><F><R><D><P><Q><E><I><K><R><A><A><T><H><L><S><W><H><P><D><G><N><R><K><L><A><V><A><Y><S><C><L><D><F><Q><R><A><P><V><G><M><S><S><D><S><Y><I><W><D><L><E><N><P><N><K><P><E><L><A><L><K><P><S><S><P><L><V><T><L><E><F><N><P><K><D><S><H><V><L><L><G><G><C><Y><N><G><Q><I><A><C><W><D><T><R><K><G><S><L><V><A><E><L><S><T><I><E><S><S><H><R><D><P><V><Y><G><T><I><W><L><Q><S><K><T><G><T><E><C><F><S><A><S><T><D><G><Q><V><M><W><W><D><I><R><K><M><S><E><P><T><E><V><V><I><L><D><I><T><K><K><E><Q><L><E><N><A><L><G><A><I><S><L><E><F><E><S><T><L><P><T><K><F><M><V><G><T><E><Q><G><I><V><I><S><C><N><R><K><A><K><T><S><A><E><K><I><V><C><T><F><P><G><H><H><G><P><I><Y><A><L><Q><R><N><P><F><Y><P><K><N><F><L><T><V><G><D><W><T><A><R><I><W><S><E><D><S><R><E><S><S><I><M><W><T><K><Y><H><M><A><Y><L><T><D><A><A><W><S><P><V><R><P><T><V><F><F><T><T><R><M><D><G><T><L><D><I><W><D><F><M><F><E><Q><C><D><P><T><L><S><L><K><V><C><D><E><A><L><F><C><L><R><V><Q><D><N><G><C><L><I><A><C><G><S><Q><L><G><T><T><T><L><L><E><V><S><P><G><L><S><T><L><Q><R><N><E><K><N><V><A><S><S><M><F><E><R><E><T><R><R><E><K><I><L><E><A><R><H><R><E><M><R><L><K><E><K><G><K><A><E><G><R><D><E><E><Q><T><D><E><E><L><A><V><D><L><E><A><L><V><S><K><A><E><E><E><F><F><D><I><I><F><A><E><L><K><K><K><E><A><D><A><I><K><L><T><P><V><P><Q><Q><P><S><P><E><E><D><Q><V><V><E><E><G><E><E><A><A><G><E><E><G><D><E><E><V><E><E><D><L><A>
Part of the dynein complex of respiratory cilia.<BOP>
Q9GZS0
Q5T6V5
QSPP_HUMAN
Queuosine salvage protein
Homo
<M><D><G><L><L><N><P><R><E><S><S><K><F><I><A><E><N><S><R><D><V><F><I><D><S><G><G><V><R><R><V><A><E><L><L><L><A><K><A><A><G><P><E><L><R><V><E><G><W><K><A><L><H><E><L><N><P><R><A><A><D><E><A><A><V><N><W><V><F><V><T><D><T><L><N><F><S><F><W><S><E><Q><D><E><H><K><C><V><V><R><Y><R><G><K><T><Y><S><G><Y><W><S><L><C><A><A><V><N><R><A><L><D><E><G><I><P><I><T><S><A><S><Y><Y><A><T><V><T><L><D><Q><V><R><N><I><L><R><S><D><T><D><V><S><M><P><L><V><E><E><R><H><R><I><L><N><E><T><G><K><I><L><L><E><K><F><G><G><S><F><L><N><C><V><R><E><S><E><N><S><A><Q><K><L><M><H><L><V><V><E><S><F><P><S><Y><R><D><V><T><L><F><E><G><K><R><V><S><F><Y><K><R><A><Q><I><L><V><A><D><T><W><S><V><L><E><G><K><G><D><G><C><F><K><D><I><S><S><I><T><M><F><A><D><Y><R><L><P><Q><V><L><A><H><L><G><A><L><K><Y><S><D><D><L><L><K><K><L><L><K><G><E><M><L><S><Y><G><D><R><Q><E><V><E><I><R><G><C><S><L><W><C><V><E><L><I><R><D><C><L><L><E><L><I><E><Q><K><G><E><K><P><N><G><E><I><N><S><I><L><L><D><Y><Y><L><W><D><Y><A><H><D><H><R><E><D><M><K><G><I><P><F><H><R><I><R><C><I><Y><Y>
Involved in salvaging queuosine.<BOP>
Q5T6V5
A6NIR3
AGAP5_HUMAN
Centaurin-gamma-like family member 2
Homo
<M><G><N><I><L><T><C><C><V><H><P><S><V><S><L><E><F><D><Q><Q><Q><G><S><V><C><P><S><E><S><E><I><Y><E><A><G><A><G><D><R><M><A><G><A><P><M><A><A><A><V><Q><P><A><E><V><T><V><E><V><G><E><D><L><H><M><H><H><I><R><D><Q><E><M><P><E><A><L><E><F><S><L><S><A><N><P><E><A><S><T><I><F><Q><R><N><S><Q><T><D><A><L><E><F><N><P><S><A><N><P><E><A><S><T><I><F><Q><R><N><S><Q><T><D><V><V><E><I><R><R><S><N><C><T><N><H><V><S><T><E><R><F><S><Q><Q><Y><S><S><C><S><T><I><F><L><D><D><S><T><A><S><Q><H><Y><L><T><M><T><I><I><S><V><T><L><E><I><P><H><H><I><T><Q><R><D><A><D><R><S><L><S><I><P><D><E><Q><L><H><S><F><A><V><S><T><V><H><I><T><K><N><R><N><G><G><G><S><L><N><N><Y><S><S><S><I><P><S><T><P><S><T><S><Q><E><D><P><Q><F><S><V><P><P><T><A><N><T><P><T><P><V><C><K><R><S><M><R><W><S><N><L><F><T><S><E><K><G><S><H><P><D><K><E><R><K><A><P><E><N><H><A><D><T><I><G><S><G><R><A><I><P><I><K><Q><G><M><L><L><K><R><S><G><K><W><L><K><T><W><K><K><K><Y><V><T><L><C><S><N><G><V><L><T><Y><Y><S><S><L><G><D><Y><M><K><N><I><H><K><K><E><I><D><L><R><T><S><T><I><K><V><P><G><K><W><P><S><L><A><T><S><A><C><A><P><I><S><S><S><K><S><N><G><L><S><K><D><M><D><T><G><L><G><D><S><I><C><F><S><P><S><I><S><S><T><T><S><P><K><L><N><P><P><P><S><P><H><A><N><K><K><K><H><L><K><K><K><S><T><N><N><F><M><I><V><S><A><T><G><Q><T><W><H><F><E><A><T><T><Y><E><E><R><D><A><W><V><Q><A><I><Q><S><Q><I><L><A><S><L><Q><S><C><E><S><S><K><S><K><S><Q><L><T><S><Q><S><E><A><M><A><L><Q><S><I><Q><N><M><R><G><N><A><H><C><V><D><Y><E><T><Q><N><P><K><W><A><S><L><N><L><G><V><L><M><C><I><E><C><S><G><I><H><R><S><L><G><T><R><L><S><R><V><R><S><L><E><L><D><D><W><P><V><E><L><R><K><V><M><S><S><I><G><N><D><L><A><N><S><I><W><E><G><S><S><Q><G><Q><T><K><P><S><V><K><S><T><R><E><E><K><E><R><W><I><R><S><K><Y><E><E><K><L><F><L><A><P><L><P><C><T><E><L><S><L><G><Q><H><L><L><R><A><T><A><D><E><D><L><Q><T><A><I><L><L><L><A><H><G><S><R><E><E><V><N><E><T><C><G><E><G><D><G><C><T><A><L><H><L><A><C><R><K><G><N><V><V><L><A><Q><L><L><I><W><Y><G><V><D><V><M><A><R><D><A><H><G><N><T><A><L><T><Y><A><R><Q><A><S><S><Q><E><C><I><N><V><L><L><Q><Y><G><C><P><D><E><C><V>
Putative GTPase-activating protein.<BOP>
A6NIR3
P49682
CXCR3_HUMAN
Interferon-inducible protein 10 receptor
Homo
<M><V><L><E><V><S><D><H><Q><V><L><N><D><A><E><V><A><A><L><L><E><N><F><S><S><S><Y><D><Y><G><E><N><E><S><D><S><C><C><T><S><P><P><C><P><Q><D><F><S><L><N><F><D><R><A><F><L><P><A><L><Y><S><L><L><F><L><L><G><L><L><G><N><G><A><V><A><A><V><L><L><S><R><R><T><A><L><S><S><T><D><T><F><L><L><H><L><A><V><A><D><T><L><L><V><L><T><L><P><L><W><A><V><D><A><A><V><Q><W><V><F><G><S><G><L><C><K><V><A><G><A><L><F><N><I><N><F><Y><A><G><A><L><L><L><A><C><I><S><F><D><R><Y><L><N><I><V><H><A><T><Q><L><Y><R><R><G><P><P><A><R><V><T><L><T><C><L><A><V><W><G><L><C><L><L><F><A><L><P><D><F><I><F><L><S><A><H><H><D><E><R><L><N><A><T><H><C><Q><Y><N><F><P><Q><V><G><R><T><A><L><R><V><L><Q><L><V><A><G><F><L><L><P><L><L><V><M><A><Y><C><Y><A><H><I><L><A><V><L><L><V><S><R><G><Q><R><R><L><R><A><M><R><L><V><V><V><V><V><V><A><F><A><L><C><W><T><P><Y><H><L><V><V><L><V><D><I><L><M><D><L><G><A><L><A><R><N><C><G><R><E><S><R><V><D><V><A><K><S><V><T><S><G><L><G><Y><M><H><C><C><L><N><P><L><L><Y><A><F><V><G><V><K><F><R><E><R><M><W><M><L><L><L><R><L><G><C><P><N><Q><R><G><L><Q><R><Q><P><S><S><S><R><R><D><S><S><W><S><E><T><S><E><A><S><Y><S><G><L>
Mediates the activity of CXCL11.<BOP>
P49682
Q14161
GIT2_HUMAN
GRK-interacting protein 2
Homo
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GTPase-activating protein for ADP ribosylation factor family members, including ARF1.<BOP>
Q14161