Datasets:
yangzhang33
/
Prot2Text-Diff-HUMAN-func256-seq768

Dataset card Data Studio Files
xet
Community
1
accession
stringlengths
6
10
name
stringlengths
8
11
Full Name
stringlengths
2
102
⌀
taxon
stringclasses
1 value
sequence
stringlengths
48
2.3k
function
stringlengths
15
1.34k
AlphaFoldDB
stringlengths
6
10
Q01518
CAP1_HUMAN
Adenylyl cyclase-associated protein 1
Homo
<M><A><D><M><Q><N><L><V><E><R><L><E><R><A><V><G><R><L><E><A><V><S><H><T><S><D><M><H><R><G><Y><A><D><S><P><S><K><A><G><A><A><P><Y><V><Q><A><F><D><S><L><L><A><G><P><V><A><E><Y><L><K><I><S><K><E><I><G><G><D><V><Q><K><H><A><E><M><V><H><T><G><L><K><L><E><R><A><L><L><V><T><A><S><Q><C><Q><Q><P><A><E><N><K><L><S><D><L><L><A><P><I><S><E><Q><I><K><E><V><I><T><F><R><E><K><N><R><G><S><K><L><F><N><H><L><S><A><V><S><E><S><I><Q><A><L><G><W><V><A><M><A><P><K><P><G><P><Y><V><K><E><M><N><D><A><A><M><F><Y><T><N><R><V><L><K><E><Y><K><D><V><D><K><K><H><V><D><W><V><K><A><Y><L><S><I><W><T><E><L><Q><A><Y><I><K><E><F><H><T><T><G><L><A><W><S><K><T><G><P><V><A><K><E><L><S><G><L><P><S><G><P><S><A><G><S><C><P><P><P><P><P><P><C><P><P><P><P><P><V><S><T><I><S><C><S><Y><E><S><A><S><R><S><S><L><F><A><Q><I><N><Q><G><E><S><I><T><H><A><L><K><H><V><S><D><D><M><K><T><H><K><N><P><A><L><K><A><Q><S><G><P><V><R><S><G><P><K><P><F><S><A><P><K><P><Q><T><S><P><S><P><K><R><A><T><K><K><E><P><A><V><L><E><L><E><G><K><K><W><R><V><E><N><Q><E><N><V><S><N><L><V><I><E><D><T><E><L><K><Q><V><A><Y><I><Y><K><C><V><N><T><T><L><Q><I><K><G><K><I><N><S><I><T><V><D><N><C><K><K><L><G><L><V><F><D><D><V><V><G><I><V><E><I><I><N><S><K><D><V><K><V><Q><V><M><G><K><V><P><T><I><S><I><N><K><T><D><G><C><H><A><Y><L><S><K><N><S><L><D><C><E><I><V><S><A><K><S><S><E><M><N><V><L><I><P><T><E><G><G><D><F><N><E><F><P><V><P><E><Q><F><K><T><L><W><N><G><Q><K><L><V><T><T><V><T><E><I><A><G>
Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.<BOP>
Q01518
P00742
FA10_HUMAN
Activated factor Xa heavy chain
Homo
<M><G><R><P><L><H><L><V><L><L><S><A><S><L><A><G><L><L><L><L><G><E><S><L><F><I><R><R><E><Q><A><N><N><I><L><A><R><V><T><R><A><N><S><F><L><E><E><M><K><K><G><H><L><E><R><E><C><M><E><E><T><C><S><Y><E><E><A><R><E><V><F><E><D><S><D><K><T><N><E><F><W><N><K><Y><K><D><G><D><Q><C><E><T><S><P><C><Q><N><Q><G><K><C><K><D><G><L><G><E><Y><T><C><T><C><L><E><G><F><E><G><K><N><C><E><L><F><T><R><K><L><C><S><L><D><N><G><D><C><D><Q><F><C><H><E><E><Q><N><S><V><V><C><S><C><A><R><G><Y><T><L><A><D><N><G><K><A><C><I><P><T><G><P><Y><P><C><G><K><Q><T><L><E><R><R><K><R><S><V><A><Q><A><T><S><S><S><G><E><A><P><D><S><I><T><W><K><P><Y><D><A><A><D><L><D><P><T><E><N><P><F><D><L><L><D><F><N><Q><T><Q><P><E><R><G><D><N><N><L><T><R><I><V><G><G><Q><E><C><K><D><G><E><C><P><W><Q><A><L><L><I><N><E><E><N><E><G><F><C><G><G><T><I><L><S><E><F><Y><I><L><T><A><A><H><C><L><Y><Q><A><K><R><F><K><V><R><V><G><D><R><N><T><E><Q><E><E><G><G><E><A><V><H><E><V><E><V><V><I><K><H><N><R><F><T><K><E><T><Y><D><F><D><I><A><V><L><R><L><K><T><P><I><T><F><R><M><N><V><A><P><A><C><L><P><E><R><D><W><A><E><S><T><L><M><T><Q><K><T><G><I><V><S><G><F><G><R><T><H><E><K><G><R><Q><S><T><R><L><K><M><L><E><V><P><Y><V><D><R><N><S><C><K><L><S><S><S><F><I><I><T><Q><N><M><F><C><A><G><Y><D><T><K><Q><E><D><A><C><Q><G><D><S><G><G><P><H><V><T><R><F><K><D><T><Y><F><V><T><G><I><V><S><W><G><E><G><C><A><R><K><G><K><Y><G><I><Y><T><K><V><T><A><F><L><K><W><I><D><R><S><M><K><T><R><G><L><P><K><A><K><S><H><A><P><E><V><I><T><S><S><P><L><K>
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.<BOP>
P00742
P09651
ROA1_HUMAN
Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Homo
<M><S><K><S><E><S><P><K><E><P><E><Q><L><R><K><L><F><I><G><G><L><S><F><E><T><T><D><E><S><L><R><S><H><F><E><Q><W><G><T><L><T><D><C><V><V><M><R><D><P><N><T><K><R><S><R><G><F><G><F><V><T><Y><A><T><V><E><E><V><D><A><A><M><N><A><R><P><H><K><V><D><G><R><V><V><E><P><K><R><A><V><S><R><E><D><S><Q><R><P><G><A><H><L><T><V><K><K><I><F><V><G><G><I><K><E><D><T><E><E><H><H><L><R><D><Y><F><E><Q><Y><G><K><I><E><V><I><E><I><M><T><D><R><G><S><G><K><K><R><G><F><A><F><V><T><F><D><D><H><D><S><V><D><K><I><V><I><Q><K><Y><H><T><V><N><G><H><N><C><E><V><R><K><A><L><S><K><Q><E><M><A><S><A><S><S><S><Q><R><G><R><S><G><S><G><N><F><G><G><G><R><G><G><G><F><G><G><N><D><N><F><G><R><G><G><N><F><S><G><R><G><G><F><G><G><S><R><G><G><G><G><Y><G><G><S><G><D><G><Y><N><G><F><G><N><D><G><G><Y><G><G><G><G><P><G><Y><S><G><G><S><R><G><Y><G><S><G><G><Q><G><Y><G><N><Q><G><S><G><Y><G><G><S><G><S><Y><D><S><Y><N><N><G><G><G><G><G><F><G><G><G><S><G><S><N><F><G><G><G><G><S><Y><N><D><F><G><N><Y><N><N><Q><S><S><N><F><G><P><M><K><G><G><N><F><G><G><R><S><S><G><P><Y><G><G><G><G><Q><Y><F><A><K><P><R><N><Q><G><G><Y><G><G><S><S><S><S><S><S><Y><G><S><G><R><R><F>
(Microbial infection) Cleavage by Enterovirus 71 protease 3C results in increased translation of apoptosis protease activating factor APAF1, leading to apoptosis.<BOP>
P09651
Q8NGS9
O13C2_HUMAN
Olfactory receptor OR9-12
Homo
<M><E><W><E><N><H><T><I><L><V><E><F><F><L><K><G><L><S><G><H><P><R><L><E><L><L><F><F><V><L><I><F><I><M><Y><V><V><I><L><L><G><N><G><T><L><I><L><I><S><I><L><D><P><H><L><H><T><P><M><Y><F><F><L><G><N><L><S><F><L><D><I><C><Y><T><T><T><S><I><P><S><T><L><V><S><F><L><S><E><R><K><T><I><S><L><S><G><C><A><V><Q><M><F><L><G><L><A><M><G><T><T><E><C><V><L><L><G><M><M><A><F><D><R><Y><V><A><I><C><N><P><L><R><Y><P><I><I><M><S><K><D><A><Y><V><P><M><A><A><G><S><W><I><I><G><A><V><N><S><A><V><Q><S><V><F><V><V><Q><L><P><F><C><R><N><N><I><I><N><H><F><T><C><E><I><L><A><V><M><K><L><A><C><A><D><I><S><D><N><E><F><I><M><L><V><A><T><T><L><F><I><L><T><P><L><L><L><I><I><V><S><Y><T><L><I><I><V><S><I><F><K><I><S><S><S><E><G><R><S><K><A><S><S><T><C><S><A><H><L><T><V><V><I><I><F><Y><G><T><I><L><F><M><Y><M><K><P><K><S><K><E><T><L><N><S><D><D><L><D><A><T><D><K><I><I><S><M><F><Y><G><V><M><T><P><M><M><N><P><L><I><Y><S><L><R><N><K><D><V><K><E><A><V><K><H><L><L><N><R><R><F><F><S><K>
Odorant receptor.<BOP>
Q8NGS9
P31267
HXA6_HUMAN
Homeobox protein Hox-1B
Homo
<M><S><S><Y><F><V><N><P><T><F><P><G><S><L><P><S><G><Q><D><S><F><L><G><Q><L><P><L><Y><Q><A><G><Y><D><A><L><R><P><F><P><A><S><Y><G><A><S><S><L><P><D><K><T><Y><T><S><P><C><F><Y><Q><Q><S><N><S><V><L><A><C><N><R><A><S><Y><E><Y><G><A><S><C><F><Y><S><D><K><D><L><S><G><A><S><P><S><G><S><G><K><Q><R><G><P><G><D><Y><L><H><F><S><P><E><Q><Q><Y><K><P><D><S><S><S><G><Q><G><K><A><L><H><D><E><G><A><D><R><K><Y><T><S><P><V><Y><P><W><M><Q><R><M><N><S><C><A><G><A><V><Y><G><S><H><G><R><R><G><R><Q><T><Y><T><R><Y><Q><T><L><E><L><E><K><E><F><H><F><N><R><Y><L><T><R><R><R><R><I><E><I><A><N><A><L><C><L><T><E><R><Q><I><K><I><W><F><Q><N><R><R><M><K><W><K><K><E><N><K><L><I><N><S><T><Q><P><S><G><E><D><S><E><A><K><A><G><E>
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP>
P31267
P01704
LV214_HUMAN
Ig lambda chain V-II region VIL
Homo
<M><A><W><A><L><L><L><L><T><L><L><T><Q><G><T><G><S><W><A><Q><S><A><L><T><Q><P><A><S><V><S><G><S><P><G><Q><S><I><T><I><S><C><T><G><T><S><S><D><V><G><G><Y><N><Y><V><S><W><Y><Q><Q><H><P><G><K><A><P><K><L><M><I><Y><E><V><S><N><R><P><S><G><V><S><N><R><F><S><G><S><K><S><G><N><T><A><S><L><T><I><S><G><L><Q><A><E><D><E><A><D><Y><Y><C><S><S><Y><T><S><S><S><T><L><H><S>
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen .<BOP>
P01704
Q8NGB6
OR4M2_HUMAN
Olfactory receptor OR15-3
Homo
<M><E><T><A><N><Y><T><K><V><T><E><F><V><L><T><G><L><S><Q><T><P><E><V><Q><L><V><L><F><V><I><F><L><S><F><Y><L><F><I><L><P><G><N><I><L><I><I><C><T><I><S><L><D><P><H><L><T><S><P><M><Y><F><L><L><A><N><L><A><F><L><D><I><W><Y><S><S><I><T><A><P><E><M><L><I><D><F><F><V><E><R><K><I><I><S><F><D><G><C><I><A><Q><L><F><F><L><H><F><A><G><A><S><E><M><F><L><L><T><V><M><A><F><D><L><Y><T><A><I><C><R><P><L><H><Y><A><T><I><M><N><Q><R><L><C><C><I><L><V><A><L><S><W><R><G><G><F><I><H><S><I><I><Q><V><A><L><I><V><R><L><P><F><C><G><P><N><E><L><D><S><Y><F><C><D><I><T><Q><V><V><R><I><A><C><A><N><T><F><P><E><E><L><V><M><I><C><S><S><G><L><I><S><V><V><C><L><I><A><L><L><M><S><Y><A><F><L><L><A><L><F><K><K><L><S><G><S><G><E><N><T><N><R><A><M><S><T><C><Y><S><H><I><T><I><V><V><L><M><F><G><P><S><I><Y><I><Y><A><R><P><F><D><S><F><S><L><D><K><V><V><S><V><F><N><T><L><I><F><P><L><R><N><P><I><I><Y><T><L><R><N><K><E><V><K><A><A><M><R><K><L><V><T><K><Y><I><L><C><K><E><K>
Odorant receptor.<BOP>
Q8NGB6
Q6ZN54
DEFI8_HUMAN
Differentially expressed in FDCP 8 homolog
Homo
<M><A><I><L><S><L><R><A><P><G><P><W><Q><A><M><Q><V><W><A><D><R><T><L><L><T><P><H><T><G><V><T><S><Q><V><L><G><V><A><A><A><V><M><T><P><L><P><G><G><H><A><A><G><R><T><R><E><A><R><W><D><A><M><E><Y><D><E><K><L><A><R><F><R><Q><A><H><L><N><P><F><N><K><Q><S><G><P><R><Q><H><E><Q><G><P><G><E><E><V><P><D><V><T><P><E><E><A><L><P><E><L><P><P><G><E><P><E><F><R><C><P><E><R><V><M><D><L><G><L><S><E><D><H><F><S><R><P><V><G><L><F><L><A><S><D><V><Q><Q><L><R><Q><A><I><E><E><C><K><Q><V><I><L><E><L><P><E><Q><S><E><K><Q><K><D><A><V><V><R><L><I><H><L><R><L><K><L><Q><E><L><K><D><P><N><E><D><E><P><N><I><R><V><L><L><E><H><R><F><Y><K><E><K><S><K><S><V><K><Q><T><C><D><K><C><N><T><I><I><W><G><L><I><Q><T><W><Y><T><C><T><G><C><Y><Y><R><C><H><S><K><C><L><N><L><I><S><K><P><C><V><S><S><K><V><S><H><Q><A><E><Y><E><L><N><I><C><P><E><T><G><L><D><S><Q><D><Y><R><C><A><E><C><R><A><P><I><S><L><R><G><V><P><S><E><A><R><Q><C><D><Y><T><G><Q><Y><Y><C><S><H><C><H><W><N><D><L><A><V><I><P><A><R><V><V><H><N><W><D><F><E><P><R><K><V><S><R><C><S><M><R><Y><L><A><L><M><V><S><R><P><V><L><R><L><R><E><I><N><P><L><L><F><S><Y><V><E><E><L><V><E><I><R><K><L><R><Q><D><I><L><L><M><K><P><Y><F><I><T><C><R><E><A><M><E><A><R><L><L><L><Q><L><Q><D><R><Q><H><F><V><E><N><D><E><M><Y><S><V><Q><D><L><L><D><V><H><A><G><R><L><G><C><S><L><T><E><I><H><T><L><F><A><K><H><I><K><L><D><C><E><R><C><Q><A><K><G><F><V><C><E><L><C><R><E><G><D><V><L><F><P><F><D><S><H><T><S><V><C><A><D><C><S><A><V><F><H><R><D><C><Y><Y><D><N><S><T><T><C><P><K><C><A><R><L><S><L><R><K><Q><S><L><F><Q><E><P><G><P><D><V><E><A>
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption.<BOP>
Q6ZN54
Q9BRV3
SWET1_HUMAN
Stromal cell protein
Homo
<M><E><A><G><G><F><L><D><S><L><I><Y><G><A><C><V><V><F><T><L><G><M><F><S><A><G><L><S><D><L><R><H><M><R><M><T><R><S><V><D><N><V><Q><F><L><P><F><L><T><T><E><V><N><N><L><G><W><L><S><Y><G><A><L><K><G><D><G><I><L><I><V><V><N><T><V><G><A><A><L><Q><T><L><Y><I><L><A><Y><L><H><Y><C><P><R><K><R><V><V><L><L><Q><T><A><T><L><L><G><V><L><L><L><G><Y><G><Y><F><W><L><L><V><P><N><P><E><A><R><L><Q><Q><L><G><L><F><C><S><V><F><T><I><S><M><Y><L><S><P><L><A><D><L><A><K><V><I><Q><T><K><S><T><Q><C><L><S><Y><P><L><T><I><A><T><L><L><T><S><A><S><W><C><L><Y><G><F><R><L><R><D><P><Y><I><M><V><S><N><F><P><G><I><V><T><S><F><I><R><F><W><L><F><W><K><Y><P><Q><E><Q><D><R><N><Y><W><L><L><Q><T>
Mediates sugar transport across membranes. May stimulate V(D)J recombination by the activation of RAG1.<BOP>
Q9BRV3
Q96HJ9
FMC1_HUMAN
Formation of mitochondrial complex V assembly factor 1 homolog
Homo
<M><A><A><L><G><S><P><S><H><T><F><R><G><L><L><R><E><L><R><Y><L><S><A><A><T><G><R><P><Y><R><D><T><A><A><Y><R><Y><L><V><K><A><F><R><A><H><R><V><T><S><E><K><L><C><R><A><Q><H><E><L><H><F><Q><A><A><T><Y><L><C><L><L><R><S><I><R><K><H><V><A><L><H><Q><E><F><H><G><K><G><E><R><S><V><E><E><S><A><G><L><V><G><L><K><L><P><H><Q><P><G><G><K><G><W><E><P>
Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) .<BOP>
Q96HJ9
P31644
GBRA5_HUMAN
GABA(A) receptor subunit alpha-5
Homo
<M><D><N><G><M><F><S><G><F><I><M><I><K><N><L><L><L><F><C><I><S><M><N><L><S><S><H><F><G><F><S><Q><M><P><T><S><S><V><K><D><E><T><N><D><N><I><T><I><F><T><R><I><L><D><G><L><L><D><G><Y><D><N><R><L><R><P><G><L><G><E><R><I><T><Q><V><R><T><D><I><Y><V><T><S><F><G><P><V><S><D><T><E><M><E><Y><T><I><D><V><F><F><R><Q><S><W><K><D><E><R><L><R><F><K><G><P><M><Q><R><L><P><L><N><N><L><L><A><S><K><I><W><T><P><D><T><F><F><H><N><G><K><K><S><I><A><H><N><M><T><T><P><N><K><L><L><R><L><E><D><D><G><T><L><L><Y><T><M><R><L><T><I><S><A><E><C><P><M><Q><L><E><D><F><P><M><D><A><H><A><C><P><L><K><F><G><S><Y><A><Y><P><N><S><E><V><V><Y><V><W><T><N><G><S><T><K><S><V><V><V><A><E><D><G><S><R><L><N><Q><Y><H><L><M><G><Q><T><V><G><T><E><N><I><S><T><S><T><G><E><Y><T><I><M><T><A><H><F><H><L><K><R><K><I><G><Y><F><V><I><Q><T><Y><L><P><C><I><M><T><V><I><L><S><Q><V><S><F><W><L><N><R><E><S><V><P><A><R><T><V><F><G><V><T><T><V><L><T><M><T><T><L><S><I><S><A><R><N><S><L><P><K><V><A><Y><A><T><A><M><D><W><F><I><A><V><C><Y><A><F><V><F><S><A><L><I><E><F><A><T><V><N><Y><F><T><K><R><G><W><A><W><D><G><K><K><A><L><E><A><A><K><I><K><K><K><R><E><V><I><L><N><K><S><T><N><A><F><T><T><G><K><M><S><H><P><P><N><I><P><K><E><Q><T><P><A><G><T><S><N><T><T><S><V><S><V><K><P><S><E><E><K><T><S><E><S><K><K><T><Y><N><S><I><S><K><I><D><K><M><S><R><I><V><F><P><V><L><F><G><T><F><N><L><V><Y><W><A><T><Y><L><N><R><E><P><V><I><K><G><A><A><S><P><K>
Ligand-gated chloride channel subunit which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain . May be involved in GABA-A receptor assembly, and GABA-A receptor immobilization and accumulation by gephyrin at the synapse .<BOP>
P31644
A0A0B4J2F0
PIOS1_HUMAN
PIGB opposite strand protein 1
Homo
<M><F><R><R><L><T><F><A><Q><L><L><F><A><T><V><L><G><I><A><G><G><V><Y><I><F><Q><P><V><F><E><Q><Y><A><K><D><Q><K><E><L><K><E><K><M><Q><L><V><Q><E><S><E><E><K><K><S>
Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen.<BOP>
A0A0B4J2F0
P25100
ADA1D_HUMAN
Alpha-adrenergic receptor 1a
Homo
<M><T><F><R><D><L><L><S><V><S><F><E><G><P><R><P><D><S><S><A><G><G><S><S><A><G><G><G><G><G><S><A><G><G><A><A><P><S><E><G><P><A><V><G><G><V><P><G><G><A><G><G><G><G><G><V><V><G><A><G><S><G><E><D><N><R><S><S><A><G><E><P><G><S><A><G><A><G><G><D><V><N><G><T><A><A><V><G><G><L><V><V><S><A><Q><G><V><G><V><G><V><F><L><A><A><F><I><L><M><A><V><A><G><N><L><L><V><I><L><S><V><A><C><N><R><H><L><Q><T><V><T><N><Y><F><I><V><N><L><A><V><A><D><L><L><L><S><A><T><V><L><P><F><S><A><T><M><E><V><L><G><F><W><A><F><G><R><A><F><C><D><V><W><A><A><V><D><V><L><C><C><T><A><S><I><L><S><L><C><T><I><S><V><D><R><Y><V><G><V><R><H><S><L><K><Y><P><A><I><M><T><E><R><K><A><A><A><I><L><A><L><L><W><V><V><A><L><V><V><S><V><G><P><L><L><G><W><K><E><P><V><P><P><D><E><R><F><C><G><I><T><E><E><A><G><Y><A><V><F><S><S><V><C><S><F><Y><L><P><M><A><V><I><V><V><M><Y><C><R><V><Y><V><V><A><R><S><T><T><R><S><L><E><A><G><V><K><R><E><R><G><K><A><S><E><V><V><L><R><I><H><C><R><G><A><A><T><G><A><D><G><A><H><G><M><R><S><A><K><G><H><T><F><R><S><S><L><S><V><R><L><L><K><F><S><R><E><K><K><A><A><K><T><L><A><I><V><V><G><V><F><V><L><C><W><F><P><F><F><F><V><L><P><L><G><S><L><F><P><Q><L><K><P><S><E><G><V><F><K><V><I><F><W><L><G><Y><F><N><S><C><V><N><P><L><I><Y><P><C><S><S><R><E><F><K><R><A><F><L><R><L><L><R><C><Q><C><R><R><R><R><R><R><R><P><L><W><R><V><Y><G><H><H><W><R><A><S><T><S><G><L><R><Q><D><C><A><P><S><S><G><D><A><P><P><G><A><P><L><A><L><T><A><L><P><D><P><D><P><E><P><P><G><T><P><E><M><Q><A><P><V><A><S><R><R><K><P><P><S><A><F><R><E><W><R><L><L><G><P><F><R><R><P><T><T><Q><L><R><A><K><V><S><S><L><S><H><K><I><R><A><G><G><A><Q><R><A><E><A><A><C><A><Q><R><S><E><V><E><A><V><S><L><G><V><P><H><E><V><A><E><G><A><T><C><Q><A><Y><E><L><A><D><Y><S><N><L><R><E><T><D><I>
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.<BOP>
P25100
Q9UL49
TCFL5_HUMAN
HPV-16 E2-binding protein 1
Homo
<M><S><G><P><G><P><R><E><P><P><P><E><A><G><A><A><G><G><E><A><A><V><E><G><A><G><G><G><D><A><A><L><G><E><P><G><L><S><F><T><T><T><D><L><S><L><V><E><M><T><E><V><E><Y><T><Q><L><Q><H><I><L><C><S><H><M><E><A><A><A><D><G><E><L><E><T><R><L><N><S><A><L><L><A><A><A><G><P><G><A><G><A><G><G><F><A><A><G><G><Q><G><G><A><A><P><V><Y><P><V><L><C><P><S><A><L><A><A><D><A><P><C><L><G><H><I><D><F><Q><E><L><R><M><M><L><L><S><E><A><G><A><A><E><K><T><S><G><G><G><D><G><A><R><A><R><A><D><G><A><A><K><E><G><A><G><A><A><A><A><A><A><G><P><D><G><A><P><E><A><R><A><K><P><A><V><R><V><R><L><E><D><R><F><N><S><I><P><A><E><P><P><P><A><P><R><G><P><E><P><P><E><P><G><G><A><L><N><N><L><V><T><L><I><R><H><P><S><E><L><M><N><V><P><L><Q><Q><Q><N><K><C><T><A><L><V><K><N><K><T><A><A><T><T><T><A><L><Q><F><T><Y><P><L><F><T><T><N><A><C><S><T><S><G><N><S><N><L><S><Q><T><Q><S><S><S><N><S><C><S><V><L><E><A><A><K><H><Q><D><I><G><L><P><R><A><F><S><F><C><Y><Q><Q><E><I><E><S><T><K><Q><T><L><G><S><R><N><K><V><L><P><E><Q><V><W><I><K><V><G><E><A><A><L><C><K><Q><A><L><K><R><N><R><S><R><M><R><Q><L><D><T><N><V><E><R><R><A><L><G><E><I><Q><N><V><G><E><G><A><T><A><T><Q><G><A><W><Q><S><S><E><S><S><Q><A><N><L><G><E><Q><A><Q><S><G><P><Q><G><G><R><S><Q><R><R><E><R><H><N><R><M><E><R><D><R><R><R><R><I><R><I><C><C><D><E><L><N><L><L><V><P><F><C><N><A><E><T><D><K><A><T><T><L><Q><W><T><T><A><F><L><K><Y><I><Q><E><R><H><G><D><S><L><K><K><E><F><E><S><V><F><C><G><K><T><G><R><R><L><K><L><T><R><P><D><S><L><V><T><C><P><A><Q><G><S><L><Q><S><S><P><S><M><E><I><K>
Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.<BOP>
Q9UL49
Q9NUD9
PIGV_HUMAN
Phosphatidylinositol-glycan biosynthesis class V protein
Homo
<M><W><P><Q><D><P><S><R><K><E><V><L><R><F><A><V><S><C><R><I><L><T><L><M><L><Q><A><L><F><N><A><I><I><P><D><H><H><A><E><A><F><S><P><P><R><L><A><P><S><G><F><V><D><Q><L><V><E><G><L><L><G><G><L><S><H><W><D><A><E><H><F><L><F><I><A><E><H><G><Y><L><Y><E><H><N><F><A><F><F><P><G><F><P><L><A><L><L><V><G><T><E><L><L><R><P><L><R><G><L><L><S><L><R><S><C><L><L><I><S><V><A><S><L><N><F><L><F><F><M><L><A><A><V><A><L><H><D><L><G><C><L><V><L><H><C><P><H><Q><S><F><Y><A><A><L><L><F><C><L><S><P><A><N><V><F><L><A><A><G><Y><S><E><A><L><F><A><L><L><T><F><S><A><M><G><Q><L><E><R><G><R><V><W><T><S><V><L><L><F><A><F><A><T><G><V><R><S><N><G><L><V><S><V><G><F><L><M><H><S><Q><C><Q><G><F><F><S><S><L><T><M><L><N><P><L><R><Q><L><F><K><L><M><A><S><L><F><L><S><V><F><T><L><G><L><P><F><A><L><F><Q><Y><Y><A><Y><T><Q><F><C><L><P><G><S><A><R><P><I><P><E><P><L><V><Q><L><A><V><D><K><G><Y><R><I><A><E><G><N><E><P><P><W><C><F><W><D><V><P><L><I><Y><S><Y><I><Q><D><V><Y><W><N><V><G><F><L><K><Y><Y><E><L><K><Q><V><P><N><F><L><L><A><A><P><V><A><I><L><V><A><W><A><T><W><T><Y><V><T><T><H><P><W><L><C><L><T><L><G><L><Q><R><S><K><N><N><K><T><L><E><K><P><D><L><G><F><L><S><P><Q><V><F><V><Y><V><V><H><A><A><V><L><L><L><F><G><G><L><C><M><H><V><Q><V><L><T><R><F><L><G><S><S><T><P><I><M><Y><W><F><P><A><H><L><L><Q><D><Q><E><P><L><L><R><S><L><K><T><V><P><W><K><P><L><A><E><D><S><P><P><G><Q><K><V><P><R><N><P><I><M><G><L><L><Y><H><W><K><T><C><S><P><V><T><R><Y><I><L><G><Y><F><L><T><Y><W><L><L><G><L><L><L><H><C><N><F><L><P><W><T>
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.<BOP>
Q9NUD9
Q9H0V9
LMA2L_HUMAN
Lectin mannose-binding 2-like
Homo
<M><A><A><T><L><G><P><L><G><S><W><Q><Q><W><R><R><C><L><S><A><R><D><G><S><R><M><L><L><L><L><L><L><L><G><S><G><Q><G><P><Q><Q><V><G><A><G><Q><T><F><E><Y><L><K><R><E><H><S><L><S><K><P><Y><Q><G><V><G><T><G><S><S><S><L><W><N><L><M><G><N><A><M><V><M><T><Q><Y><I><R><L><T><P><D><M><Q><S><K><Q><G><A><L><W><N><R><V><P><C><F><L><R><D><W><E><L><Q><V><H><F><K><I><H><G><Q><G><K><K><N><L><H><G><D><G><L><A><I><W><Y><T><K><D><R><M><Q><P><G><P><V><F><G><N><M><D><K><F><V><G><L><G><V><F><V><D><T><Y><P><N><E><E><K><Q><Q><E><R><V><F><P><Y><I><S><A><M><V><N><N><G><S><L><S><Y><D><H><E><R><D><G><R><P><T><E><L><G><G><C><T><A><I><V><R><N><L><H><Y><D><T><F><L><V><I><R><Y><V><K><R><H><L><T><I><M><M><D><I><D><G><K><H><E><W><R><D><C><I><E><V><P><G><V><R><L><P><R><G><Y><Y><F><G><T><S><S><I><T><G><D><L><S><D><N><H><D><V><I><S><L><K><L><F><E><L><T><V><E><R><T><P><E><E><E><K><L><H><R><D><V><F><L><P><S><V><D><N><M><K><L><P><E><M><T><A><P><L><P><P><L><S><G><L><A><L><F><L><I><V><F><F><S><L><V><F><S><V><F><A><I><V><I><G><I><I><L><Y><N><K><W><Q><E><Q><S><R><K><R><F><Y>
May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53.<BOP>
Q9H0V9
Q96EF0
MTMR8_HUMAN
Phosphatidylinositol-3-phosphate phosphatase
Homo
<M><D><H><I><T><V><P><K><V><E><N><V><K><L><V><D><R><Y><V><S><K><K><P><A><N><G><I><L><Y><L><T><A><T><H><L><I><Y><V><E><A><S><G><A><A><R><K><E><T><W><I><A><L><H><H><I><A><T><V><E><K><L><P><I><T><S><L><G><C><P><L><T><L><R><C><K><N><F><R><V><A><H><F><V><L><D><S><D><L><V><C><H><E><V><Y><I><S><L><L><K><L><S><Q><P><A><L><P><E><D><L><Y><A><F><S><Y><N><P><K><S><S><K><E><M><R><E><S><G><W><K><L><I><D><P><I><S><D><F><G><R><M><G><I><P><N><R><N><W><T><I><T><D><A><N><R><N><Y><E><I><C><S><T><Y><P><P><E><I><V><V><P><K><S><V><T><L><G><T><V><V><G><S><S><K><F><R><S><K><E><R><V><P><V><L><S><Y><L><Y><K><E><N><N><A><A><I><C><R><C><S><Q><P><L><S><G><F><Y><T><R><C><V><D><D><E><L><L><L><E><A><I><S><Q><T><N><P><G><S><Q><F><M><Y><V><V><D><T><R><P><K><L><N><A><M><A><N><R><A><A><G><K><G><Y><E><N><E><D><N><Y><A><N><I><R><F><R><F><M><G><I><E><N><I><H><V><M><R><S><S><L><Q><K><L><L><E><V><C><E><L><K><T><P><T><M><S><E><F><L><S><G><L><E><S><S><G><W><L><R><H><I><K><A><I><M><D><A><G><I><F><I><T><K><A><V><K><V><E><K><A><S><V><L><V><H><C><S><D><G><W><D><R><T><A><Q><V><C><S><V><A><S><I><L><L><D><P><F><Y><R><T><F><K><G><L><M><I><L><I><E><K><E><W><I><S><M><G><H><K><F><S><Q><R><C><G><H><L><D><G><D><S><K><E><V><S><P><I><F><T><Q><F><L><D><C><I><W><Q><L><M><E><Q><F><P><C><A><F><E><F><N><E><N><F><L><L><E><I><H><D><H><V><F><S><C><Q><F><G><N><F><L><G><N><C><Q><K><D><R><E><D><L><R><V><Y><E><K><T><H><S><V><W><P><F><L><V><Q><R><K><P><D><F><R><N><P><L><Y><K><G><F><T><M><Y><G><V><L><N><P><S><T><V><P><Y><N><I><Q><F><W><C><G><M><Y><N><R><F><D><K><G><L><Q><P><K><Q><S><M><L><E><S><L><L><E><I><K><K><Q><R><A><M><L><E><T><D><V><H><E><L><E><K><K><L><K><V><R><D><E><P><P><E><E><I><C><T><C><S><Q><L><G><N><I><L><S><Q><H><L><G><S><P><L><T><N><P><L><G><F><M><G><I><N><G><D><L><N><T><L><M><E><N><G><T><L><S><R><E><G><G><L><R><A><Q><M><D><Q><V><K><S><Q><G><A><D><L><H><H><N><C><C><E><I><V><G><S><L><R><A><I><N><I><S><G><D><V><G><I><S><E><A><M><G><I><S><G><D><M><C><T><F><E><A><T><G><F><S><K><D><L><G><I><C><G><A><M><D><I><S><E><A><T><G><I><S><G><N><L><G><I><S><E><A><R><G><F><S><G><D><M><G><I><L><G><D><T><G><I><S><K><A><S><T><K><E><A><D><Y><S><K><H><Q>
Phosphatase that acts on lipids with a phosphoinositol headgroup . Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate . In complex with MTMR9, negatively regulates autophagy .<BOP>
Q96EF0
Q9GZS1
RPA49_HUMAN
RNA polymerase I-associated factor 53
Homo
<M><A><A><E><V><L><P><S><A><R><W><Q><Y><C><G><A><P><D><G><S><Q><R><A><V><L><V><Q><F><S><N><G><K><L><Q><S><P><G><N><M><R><F><T><L><Y><E><N><K><D><S><T><N><P><R><K><R><N><Q><R><I><L><A><A><E><T><D><R><L><S><Y><V><G><N><N><F><G><T><G><A><L><K><C><N><T><L><C><R><H><F><V><G><I><L><N><K><T><S><G><Q><M><E><V><Y><D><A><E><L><F><N><M><Q><P><L><F><S><D><V><S><V><E><S><E><L><A><L><E><S><Q><T><K><T><Y><R><E><K><M><D><S><C><I><E><A><F><G><T><T><K><Q><K><R><A><L><N><T><R><R><M><N><R><V><G><N><E><S><L><N><R><A><V><A><K><A><A><E><T><I><I><D><T><K><G><V><T><A><L><V><S><D><A><I><H><N><D><L><Q><D><D><S><L><Y><L><P><P><C><Y><D><D><A><A><K><P><E><D><V><Y><K><F><E><D><L><L><S><P><A><E><Y><E><A><L><Q><S><P><S><E><A><F><R><N><V><T><S><E><E><I><L><K><M><I><E><E><N><S><H><C><T><F><V><I><E><A><L><K><S><L><P><S><D><V><E><S><R><D><R><Q><A><R><C><I><W><F><L><D><T><L><I><K><F><R><A><H><R><V><V><K><R><K><S><A><L><G><P><G><V><P><H><I><I><N><T><K><L><L><K><H><F><T><C><L><T><Y><N><N><G><R><L><R><N><L><I><S><D><S><M><K><A><K><I><T><A><Y><V><I><I><L><A><L><H><I><H><D><F><Q><I><D><L><T><V><L><Q><R><D><L><K><L><S><E><K><R><M><M><E><I><A><K><A><M><R><L><K><I><S><K><R><R><V><S><V><A><A><G><S><E><E><D><H><K><L><G><T><L><S><L><P><L><P><P><A><Q><T><S><D><R><L><A><K><R><R><K><I><T>
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors . Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF .<BOP>
Q9GZS1
A8K830
OCAT2_HUMAN
Protein OCA-T2
Homo
<M><S><E><K><P><K><V><Y><Q><G><V><R><V><K><I><T><V><K><E><L><L><Q><Q><R><R><A><H><Q><A><A><S><G><G><T><R><S><G><G><S><S><V><H><L><S><D><P><V><A><P><S><S><A><G><L><Y><F><E><P><E><P><I><S><S><T><P><N><Y><L><Q><R><G><E><F><S><S><C><V><S><C><E><E><N><S><S><C><L><D><Q><I><F><D><S><Y><L><Q><T><E><M><H><P><E><P><L><L><N><S><T><Q><S><A><P><H><H><F><P><D><S><F><Q><A><T><P><F><C><F><N><Q><S><L><I><P><G><S><P><S><N><S><S><I><L><S><G><S><L><D><Y><S><Y><S><P><V><Q><L><P><S><Y><A><P><E><N><Y><N><S><P><A><S><L><D><T><R><T><C><G><Y><P><P><E><D><H><S><Y><Q><H><L><S><S><H><A><Q><Y><S><C><F><S><S><A><T><T><S><I><C><Y><C><A><S><C><E><A><E><D><L><D><A><L><Q><A><A><E><Y><F><Y><P><S><T><D><C><V><D><F><A><P><S><A><A><A><T><S><D><F><Y><K><R><E><T><N><C><D><I><C><Y><S>
Transcriptional coactivator that specifically associates with POU2F3 . This complex drives the development of tuft cells, a rare a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues .<BOP>
A8K830
P04732
MT1E_HUMAN
Metallothionein-IE
Homo
<M><D><P><N><C><S><C><A><T><G><G><S><C><T><C><A><G><S><C><K><C><K><E><C><K><C><T><S><C><K><K><S><C><C><S><C><C><P><V><G><C><A><K><C><A><Q><G><C><V><C><K><G><A><S><E><K><C><S><C><C><A>
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.<BOP>
P04732
Q86SG2
ANR23_HUMAN
Muscle ankyrin repeat protein 3
Homo
<M><D><F><I><S><I><Q><Q><L><V><S><G><E><R><V><E><G><K><V><L><G><F><G><H><G><V><P><D><P><G><A><W><P><S><D><W><R><R><G><P><Q><E><A><V><A><R><E><K><L><K><L><E><E><E><K><K><K><K><L><E><R><F><N><S><T><R><F><N><L><D><N><L><A><D><L><E><N><L><V><Q><R><R><K><K><R><L><R><H><R><V><P><P><R><K><P><E><P><L><V><K><P><Q><S><Q><A><Q><V><E><P><V><G><L><E><M><F><L><K><A><A><A><E><N><Q><E><Y><L><I><D><K><Y><L><T><D><G><G><D><P><N><A><H><D><K><L><H><R><T><A><L><H><W><A><C><L><K><G><H><S><Q><L><V><N><K><L><L><V><A><G><A><T><V><D><A><R><D><L><L><D><R><T><P><V><F><W><A><C><R><G><G><H><L><V><I><L><K><Q><L><L><N><Q><G><A><R><V><N><A><R><D><K><I><G><S><T><P><L><H><V><A><V><R><T><R><H><P><D><C><L><E><H><L><I><E><C><G><A><H><L><N><A><Q><D><K><E><G><D><T><A><L><H><E><A><V><R><H><G><S><Y><K><A><M><K><L><L><L><L><Y><G><A><E><L><G><V><R><N><A><A><S><V><T><P><V><Q><L><A><R><D><W><Q><R><G><I><R><E><A><L><Q><A><H><V><A><H><P><R><T><R><C>
May be involved in the energy metabolism. Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression.<BOP>
Q86SG2
P42568
AF9_HUMAN
YEATS domain-containing protein 3
Homo
<M><A><S><S><C><A><V><Q><V><K><L><E><L><G><H><R><A><Q><V><R><K><K><P><T><V><E><G><F><T><H><D><W><M><V><F><V><R><G><P><E><H><S><N><I><Q><H><F><V><E><K><V><V><F><H><L><H><E><S><F><P><R><P><K><R><V><C><K><D><P><P><Y><K><V><E><E><S><G><Y><A><G><F><I><L><P><I><E><V><Y><F><K><N><K><E><E><P><R><K><V><R><F><D><Y><D><L><F><L><H><L><E><G><H><P><P><V><N><H><L><R><C><E><K><L><T><F><N><N><P><T><E><D><F><R><R><K><L><L><K><A><G><G><D><P><N><R><S><I><H><T><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><S><T><S><F><S><K><P><H><K><L><M><K><E><H><K><E><K><P><S><K><D><S><R><E><H><K><S><A><F><K><E><P><S><R><D><H><N><K><S><S><K><E><S><S><K><K><P><K><E><N><K><P><L><K><E><E><K><I><V><P><K><M><A><F><K><E><P><K><P><M><S><K><E><P><K><P><D><S><N><L><L><T><I><T><S><G><Q><D><K><K><A><P><S><K><R><P><P><I><S><D><S><E><E><L><S><A><K><K><R><K><K><S><S><S><E><A><L><F><K><S><F><S><S><A><P><P><L><I><L><T><C><S><A><D><K><K><Q><I><K><D><K><S><H><V><K><M><G><K><V><K><I><E><S><E><T><S><E><K><K><K><S><T><L><P><P><F><D><D><I><V><D><P><N><D><S><D><V><E><E><N><I><S><S><K><S><D><S><E><Q><P><S><P><A><S><S><S><S><S><S><S><S><S><F><T><P><S><Q><T><R><Q><Q><G><P><L><R><S><I><M><K><D><L><H><S><D><D><N><E><E><E><S><D><E><V><E><D><N><D><N><D><S><E><M><E><R><P><V><N><R><G><G><S><R><S><R><R><V><S><L><S><D><G><S><D><S><E><S><S><S><A><S><S><P><L><H><H><E><P><P><P><P><L><L><K><T><N><N><N><Q><I><L><E><V><K><S><P><I><K><Q><S><K><S><D><K><Q><I><K><N><G><E><C><D><K><A><Y><L><D><E><L><V><E><L><H><R><R><L><M><T><L><R><E><R><H><I><L><Q><Q><I><V><N><L><I><E><E><T><G><H><F><H><I><T><N><T><T><F><D><F><D><L><C><S><L><D><K><T><T><V><R><K><L><Q><S><Y><L><E><T><S><G><T><S>
Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA . Specifically recognizes and binds acylated histone H3, with a preference for histone H3 that is crotonylated . Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors . Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylated at 'Lys-18' (H3K18cr) . Also recognizes and binds histone H3 acetylated and butyrylated at 'Lys-9' (H3K9ac and H3K9bu, respectively), but with lower affinity than crotonylated histone H3 . In the SEC complex, MLLT3 is required to recruit the complex to crotonylated histones . Recruitment of the SEC complex to crotonylated histones promotes recruitment of DOT1L on active chromatin to deposit histone H3 'Lys-7
P42568
P32321
DCTD_HUMAN
dCMP deaminase
Homo
<M><S><E><V><S><C><K><K><R><D><D><Y><L><E><W><P><E><Y><F><M><A><V><A><F><L><S><A><Q><R><S><K><D><P><N><S><Q><V><G><A><C><I><V><N><S><E><N><K><I><V><G><I><G><Y><N><G><M><P><N><G><C><S><D><D><V><L><P><W><R><R><T><A><E><N><K><L><D><T><K><Y><P><Y><V><C><H><A><E><L><N><A><I><M><N><K><N><S><T><D><V><K><G><C><S><M><Y><V><A><L><F><P><C><N><E><C><A><K><L><I><I><Q><A><G><I><K><E><V><I><F><M><S><D><K><Y><H><D><S><D><E><A><T><A><A><R><L><L><F><N><M><A><G><V><T><F><R><K><F><I><P><K><C><S><K><I><V><I><D><F><D><S><I><N><S><R><P><S><Q><K><L><Q>
Supplies the nucleotide substrate for thymidylate synthetase.<BOP>
P32321
Q9H0W9
CK054_HUMAN
Ester hydrolase C11orf54
Homo
<M><A><C><A><E><F><S><F><H><V><P><S><L><E><E><L><A><G><V><M><Q><K><G><L><K><D><N><F><A><D><V><Q><V><S><V><V><D><C><P><D><L><T><K><E><P><F><T><F><P><V><K><G><I><C><G><K><T><R><I><A><E><V><G><G><V><P><Y><L><L><P><L><V><N><Q><K><K><V><Y><D><L><N><K><I><A><K><E><I><K><L><P><G><A><F><I><L><G><A><G><A><G><P><F><Q><T><L><G><F><N><S><E><F><M><P><V><I><Q><T><E><S><E><H><K><P><P><V><N><G><S><Y><F><A><H><V><N><P><A><D><G><G><C><L><L><E><K><Y><S><E><K><C><H><D><F><Q><C><A><L><L><A><N><L><F><A><S><E><G><Q><P><G><K><V><I><E><V><K><A><K><R><R><T><G><P><L><N><F><V><T><C><M><R><E><T><L><E><K><H><Y><G><N><K><P><I><G><M><G><G><T><F><I><I><Q><K><G><K><V><K><S><H><I><M><P><A><E><F><S><S><C><P><L><N><S><D><E><E><V><N><K><W><L><H><F><Y><E><M><K><A><P><L><V><C><L><P><V><F><V><S><R><D><P><G><F><D><L><R><L><E><H><T><H><F><F><S><R><H><G><E><G><G><H><Y><H><Y><D><T><T><P><D><I><V><E><Y><L><G><Y><F><L><P><A><E><F><L><Y><R><I><D><Q><P><K><E><T><H><S><I><G><R><D>
Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.<BOP>
Q9H0W9
Q8IZ20
ZN683_HUMAN
Zinc finger protein 683
Homo
<M><K><E><E><S><A><A><Q><L><G><C><C><H><R><P><M><A><L><G><G><T><G><G><S><L><S><P><S><L><D><F><Q><L><F><R><G><D><Q><V><F><S><A><C><R><P><L><P><D><M><V><D><A><H><G><P><S><C><A><S><W><L><C><P><L><P><L><A><P><G><R><S><A><L><L><A><C><L><Q><D><L><D><L><N><L><C><T><P><Q><P><A><P><L><G><T><D><L><Q><G><L><Q><E><D><A><L><S><M><K><H><E><P><P><G><L><Q><A><S><S><T><D><D><K><K><F><T><V><K><Y><P><Q><N><K><D><K><L><G><K><Q><P><E><R><A><G><E><G><A><P><C><P><A><F><S><S><H><N><S><S><S><P><P><P><L><Q><N><R><K><S><P><S><P><L><A><F><C><P><C><P><P><V><N><S><I><S><K><E><L><P><F><L><L><H><A><F><Y><P><G><Y><P><L><L><L><P><P><P><H><L><F><T><Y><G><A><L><P><S><D><Q><C><P><H><L><L><M><L><P><Q><D><P><S><Y><P><T><M><A><M><P><S><L><L><M><M><V><N><E><L><G><H><P><S><A><R><W><E><T><L><L><P><Y><P><G><A><F><Q><A><S><G><Q><A><L><P><S><Q><A><R><N><P><G><A><G><A><A><P><T><D><S><P><G><L><E><R><G><G><M><A><S><P><A><K><R><V><P><L><S><S><Q><T><G><T><A><A><L><P><Y><P><L><K><K><K><N><G><K><I><L><Y><E><C><N><I><C><G><K><S><F><G><Q><L><S><N><L><K><V><H><L><R><V><H><S><G><E><R><P><F><Q><C><A><L><C><Q><K><S><F><T><Q><L><A><H><L><Q><K><H><H><L><V><H><T><G><E><R><P><H><K><C><S><I><P><W><V><P><G><R><N><H><W><K><S><F><Q><A><W><R><E><R><E><V><C><H><K><R><F><S><S><S><S><N><L><K><T><H><L><R><L><H><S><G><A><R><P><F><Q><C><S><V><C><R><S><R><F><T><Q><H><I><H><L><K><L><H><H><R><L><H><A><P><Q><P><C><G><L><V><H><T><Q><L><P><L><A><S><L><A><C><L><A><Q><W><H><Q><G><A><L><D><L><M><A><V><A><S><E><K><H><M><G><Y><D><I><D><E><V><K><V><S><S><T><S><Q><G><K><A><R><A><V><S><L><S><S><A><G><T><P><L><V><M><G><Q><D><Q><N><N>
Transcriptional repressor that binds to DNA within promoter regions of the transcriptional repressor PRDM1/BLIMP1 target sites. Regulates interferon-gamma (IFN-gamma) production in cytomegalovirus (CMV)-infected effector CD8(+) T cells.<BOP>
Q8IZ20
Q969T3
SNX21_HUMAN
Sorting nexin L
Homo
<M><H><R><G><T><Q><E><G><A><M><A><S><R><L><L><H><R><L><R><H><A><L><A><G><D><G><P><G><E><A><A><A><S><P><E><A><E><Q><F><P><E><S><S><E><L><E><D><D><D><A><E><G><L><S><S><R><L><S><G><T><L><S><F><T><S><A><E><D><D><E><D><D><E><D><E><D><D><E><E><A><G><P><D><Q><L><P><L><G><D><G><T><S><G><E><D><A><E><R><S><P><P><P><D><G><Q><W><G><S><Q><L><L><A><R><Q><L><Q><D><F><W><K><K><S><R><N><T><L><A><P><Q><R><L><L><F><E><V><T><S><A><N><V><V><K><D><P><P><S><K><Y><V><L><Y><T><L><A><V><I><G><P><G><P><P><D><C><Q><P><A><Q><I><S><R><R><Y><S><D><F><E><R><L><H><R><N><L><Q><R><Q><F><R><G><P><M><A><A><I><S><F><P><R><K><R><L><R><R><N><F><T><A><E><T><I><A><R><R><S><R><A><F><E><Q><F><L><G><H><L><Q><A><V><P><E><L><R><H><A><P><D><L><Q><D><F><F><V><L><P><E><L><R><R><A><Q><S><L><T><C><T><G><L><Y><R><E><A><L><A><L><W><A><N><A><W><Q><L><Q><A><Q><L><G><T><P><S><G><P><D><R><P><L><L><T><L><A><G><L><A><V><C><H><Q><E><L><E><D><P><G><E><A><R><A><C><C><E><K><A><L><Q><L><L><G><D><K><S><L><H><P><L><L><A><P><F><L><E><A><H><V><R><L><S><W><R><L><G><L><D><K><R><Q><S><E><A><R><L><Q><A><L><Q><E><A><G><L><T><P><T><P><P><P><S><L><K><E><L><L><I><K><E><V><L><D>
Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate. May be involved in several stages of intracellular trafficking.<BOP>
Q969T3
A6NGU5
GGT3_HUMAN
Putative glutathione hydrolase 3 light chain
Homo
<M><K><K><K><L><V><V><L><G><L><L><A><V><V><L><V><L><V><I><V><G><L><C><L><W><L><P><S><A><S><K><E><P><D><N><H><V><Y><T><R><A><A><V><A><A><D><A><K><Q><C><L><E><I><G><R><D><T><L><R><D><G><G><S><A><V><D><A><A><I><A><A><L><L><C><V><G><L><M><N><A><H><S><M><G><I><G><V><G><L><F><L><T><I><Y><N><S><T><T><R><K><A><E><V><I><N><A><R><E><V><A><P><R><L><A><F><A><S><M><F><N><S><S><E><Q><S><Q><K><G><G><L><S><V><A><V><P><G><E><I><R><G><Y><E><L><A><H><Q><R><H><G><R><L><P><W><A><R><L><F><Q><P><S><I><Q><L><A><R><Q><G><F><P><V><G><K><G><L><A><A><V><L><E><N><K><R><T><V><I><E><Q><Q><P><V><L><C><E><V><F><C><R><D><R><K><V><L><R><E><G><E><R><L><T><L><P><R><L><A><D><T><Y><E><M><L><A><I><E><G><A><Q><A><F><Y><N><G><S><L><M><A><Q><I><V><K><D><I><Q><A><A><G><G><I><V><T><A><E><D><L><N><N><Y><C><A><E><L><I><E><H><P><L><N><I><S><L><G><D><A><V><L><Y><M><P><S><A><R><L><S><G><P><V><L><A><L><I><L><N><I><L><K><G><Y><N><F><S><R><E><S><V><E><T><P><E><Q><K><G><L><T><Y><H><R><I><V><E><A><F><R><F><A><Y><A><K><R><T><L><L><G><D><P><K><F><V><D><V><T><E><V><V><R><N><M><T><S><E><F><F><A><A><Q><L><R><S><Q><I><S><D><H><T><T><H><P><I><S><Y><Y><K><P><E><F><Y><T><P><D><D><G><G><T><A><H><L><S><V><V><A><E><D><G><S><A><V><S><A><T><S><T><I><N><L><Y><F><G><S><K><V><C><S><P><V><S><G><I><L><F><N><N><M><D><D><F><S><S><P><S><I><T><N><E><F><G><A><P><P><S><P><A><N><F><I><Q><P><G><K><Q><P><L><L><S><M><C><P><T><I><M><V><G><Q><D><G><Q><V><R><M><V><V><G><A><A><G><G><T><Q><I><T><T><D><T><A><L><A><I><I><Y><N><L><W><F><G><Y><D><V><K><R><A><V><E><E><P><R><L><H><N><K><L><L><P><N><V><T><T><V><E><R><N><I><D><Q><A><V><T><A><A><L><E><T><R><H><H><H><T><Q><I><A><S><T><F><I><A><V><V><Q><A><I><V><R><T><A><G><G><W><A><A><A><S><D><S><R><K><G><G><E><P><A><G><Y>
Hydrolyzes and transfers gamma-glutamyl moieties from glutathione and other gamma-glutamyl compounds to acceptors.<BOP>
A6NGU5
Q9NYP3
DONS_HUMAN
B17
Homo
<M><A><L><S><V><P><G><Y><S><P><G><F><R><K><P><P><E><V><V><R><L><R><R><K><R><A><R><S><R><G><A><A><A><S><P><P><R><E><L><T><E><P><A><A><R><R><A><A><L><V><A><G><L><P><L><R><P><F><P><A><A><G><G><R><G><G><G><S><G><G><G><P><A><A><A><R><R><N><P><F><A><R><L><D><N><R><P><R><V><A><A><E><P><P><D><G><P><A><R><E><Q><P><E><A><P><V><P><F><L><D><S><N><Q><E><N><D><L><L><W><E><E><K><F><P><E><R><T><T><V><T><E><L><P><Q><T><S><H><V><S><F><S><E><P><D><I><P><S><S><K><S><T><E><L><P><V><D><W><S><I><K><T><R><L><L><F><T><S><S><Q><P><F><T><W><A><D><H><L><K><A><Q><E><E><A><Q><G><L><V><Q><H><C><R><A><T><E><V><T><L><P><K><S><I><Q><D><P><K><L><S><S><E><L><R><C><T><F><Q><Q><S><L><I><Y><W><L><H><P><A><L><S><W><L><P><L><F><P><R><I><G><A><D><R><K><M><A><G><K><T><S><P><W><S><N><D><A><T><L><Q><H><V><L><M><S><D><W><S><V><S><F><T><S><L><Y><N><L><L><K><T><K><L><C><P><Y><F><Y><V><C><T><Y><Q><F><T><V><L><F><R><A><A><G><L><A><G><S><D><L><I><T><A><L><I><S><P><T><T><R><G><L><R><E><A><M><R><N><E><G><I><E><F><S><L><P><L><I><K><E><S><G><H><K><K><E><T><A><S><G><T><S><L><G><Y><G><E><E><Q><A><I><S><D><E><D><E><E><E><S><F><S><W><L><E><E><M><G><V><Q><D><K><I><K><K><P><D><I><L><S><I><K><L><R><K><E><K><H><E><V><Q><M><D><H><R><P><E><S><V><V><L><V><K><G><I><N><T><F><T><L><L><N><F><L><I><N><S><K><S><L><V><A><T><S><G><P><Q><A><G><L><P><P><T><L><L><S><P><V><A><F><R><G><A><T><M><Q><M><L><K><A><R><S><V><N><V><K><T><Q><A><L><S><G><Y><R><D><Q><F><S><L><E><I><T><G><P><I><M><P><H><S><L><H><S><L><T><M><L><L><K><S><S><Q><S><G><S><F><S><A><V><L><Y><P><H><E><P><T><A><V><F><N><I><C><L><Q><M><D><K><V><L><D><M><E><V><V><H><K><E><L><T><N><C><G><L><H><P><N><T><L><E><Q><L><S><Q><I><P><L><L><G><K><S><S><L><R><N><V><V><L><R><D><Y><I><Y><N><W><R><S>
Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability.<BOP>
Q9NYP3
Q9P2K3
RCOR3_HUMAN
REST corepressor 3
Homo
<M><R><V><G><A><E><Y><Q><A><R><I><P><E><F><D><P><G><A><T><K><Y><T><D><K><D><N><G><G><M><L><V><W><S><P><Y><H><S><I><P><D><A><K><L><D><E><Y><I><A><I><A><K><E><K><H><G><Y><N><V><E><Q><A><L><G><M><L><F><W><H><K><H><N><I><E><K><S><L><A><D><L><P><N><F><T><P><F><P><D><E><W><T><V><E><D><K><V><L><F><E><Q><A><F><S><F><H><G><K><S><F><H><R><I><Q><Q><M><L><P><D><K><T><I><A><S><L><V><K><Y><Y><Y><S><W><K><K><T><R><S><R><T><S><L><M><D><R><Q><A><R><K><L><A><N><R><H><N><Q><G><D><S><D><D><D><V><E><E><T><H><P><M><D><G><N><D><S><D><Y><D><P><K><K><E><A><K><K><E><G><N><T><E><Q><P><V><Q><T><S><K><I><G><L><G><R><R><E><Y><Q><S><L><Q><H><R><H><H><S><Q><R><S><K><C><R><P><P><K><G><M><Y><L><T><Q><E><D><V><V><A><V><S><C><S><P><N><A><A><N><T><I><L><R><Q><L><D><M><E><L><I><S><L><K><R><Q><V><Q><N><A><K><Q><V><N><S><A><L><K><Q><K><M><E><G><G><I><E><E><F><K><P><P><E><S><N><Q><K><I><N><A><R><W><T><T><E><E><Q><L><L><A><V><Q><G><V><R><K><Y><G><K><D><F><Q><A><I><A><D><V><I><G><N><K><T><V><G><Q><V><K><N><F><F><V><N><Y><R><R><R><F><N><L><E><E><V><L><Q><E><W><E><A><E><Q><G><T><Q><A><S><N><G><D><A><S><T><L><G><E><E><T><K><S><A><S><N><V><P><S><G><K><S><T><D><E><E><E><E><A><Q><T><P><Q><A><P><R><T><L><G><P><S><P><P><A><P><S><S><T><P><T><P><T><A><P><I><A><T><L><N><Q><P><P><P><L><L><R><P><T><L><P><A><A><P><A><L><H><R><Q><P><P><P><L><Q><Q><Q><A><R><F><I><Q><P><R><P><T><L><N><Q><P><P><P><P><L><I><R><P><A><N><S><M><P><P><R><L><N><P><R><P><V><L><S><T><V><G><G><Q><Q><P><P><S><L><I><G><I><Q><T><D><S><Q><S><S><L><H>
May act as a component of a corepressor complex that represses transcription.<BOP>
Q9P2K3
Q9P127
LUZP4_HUMAN
Tumor antigen HOM-TES-85
Homo
<M><A><S><F><R><K><L><T><L><S><E><K><V><P><P><N><H><P><S><R><K><K><V><N><F><L><D><M><S><L><D><D><I><I><I><Y><K><E><L><E><G><T><N><A><E><E><E><K><N><K><R><Q><N><H><S><K><K><E><S><P><S><R><Q><Q><S><K><A><H><R><H><R><H><R><R><G><Y><S><R><C><R><S><N><S><E><E><G><N><H><D><K><K><P><S><Q><K><P><S><G><F><K><S><G><Q><H><P><L><N><G><Q><P><L><I><E><Q><E><K><C><S><D><N><Y><E><A><Q><A><E><K><N><Q><G><Q><S><E><G><N><Q><H><Q><S><E><G><N><P><D><K><S><E><E><S><Q><G><Q><P><E><E><N><H><H><S><E><R><S><R><N><H><L><E><R><S><L><S><Q><S><D><R><S><Q><G><Q><L><K><R><H><H><P><Q><Y><E><R><S><H><G><Q><Y><K><R><S><H><G><Q><S><E><R><S><H><G><H><S><E><R><S><H><G><H><S><E><R><S><H><G><H><S><E><R><S><H><G><H><S><K><R><S><R><S><Q><G><D><L><V><D><T><Q><S><D><L><I><A><T><Q><R><D><L><I><A><T><Q><K><D><L><I><A><T><Q><R><D><L><I><A><T><Q><R><D><L><I><V><T><Q><R><D><L><V><A><T><E><R><D><L><I><N><Q><S><G><R><S><H><G><Q><S><E><R><H><Q><R><Y><S><T><G><K><N><T><I><T><T>
Export adapter involved in mRNA nuclear export in cancer cells. Binds and enhances the RNA-binding activity of the nuclear RNA export factor NXF1. Can restore mRNA export function in cells compromised by loss of mRNA export adapters .<BOP>
Q9P127
P19957
ELAF_HUMAN
WAP four-disulfide core domain protein 14
Homo
<M><R><A><S><S><F><L><I><V><V><V><F><L><I><A><G><T><L><V><L><E><A><A><V><T><G><V><P><V><K><G><Q><D><T><V><K><G><R><V><P><F><N><G><Q><D><P><V><K><G><Q><V><S><V><K><G><Q><D><K><V><K><A><Q><E><P><V><K><G><P><V><S><T><K><P><G><S><C><P><I><I><L><I><R><C><A><M><L><N><P><P><N><R><C><L><K><D><T><D><C><P><G><I><K><K><C><C><E><G><S><C><G><M><A><C><F><V><P><Q>
Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1) .<BOP>
P19957
P51686
CCR9_HUMAN
GPR-9-6
Homo
<M><T><P><T><D><F><T><S><P><I><P><N><M><A><D><D><Y><G><S><E><S><T><S><S><M><E><D><Y><V><N><F><N><F><T><D><F><Y><C><E><K><N><N><V><R><Q><F><A><S><H><F><L><P><P><L><Y><W><L><V><F><I><V><G><A><L><G><N><S><L><V><I><L><V><Y><W><Y><C><T><R><V><K><T><M><T><D><M><F><L><L><N><L><A><I><A><D><L><L><F><L><V><T><L><P><F><W><A><I><A><A><A><D><Q><W><K><F><Q><T><F><M><C><K><V><V><N><S><M><Y><K><M><N><F><Y><S><C><V><L><L><I><M><C><I><S><V><D><R><Y><I><A><I><A><Q><A><M><R><A><H><T><W><R><E><K><R><L><L><Y><S><K><M><V><C><F><T><I><W><V><L><A><A><A><L><C><I><P><E><I><L><Y><S><Q><I><K><E><E><S><G><I><A><I><C><T><M><V><Y><P><S><D><E><S><T><K><L><K><S><A><V><L><T><L><K><V><I><L><G><F><F><L><P><F><V><V><M><A><C><C><Y><T><I><I><I><H><T><L><I><Q><A><K><K><S><S><K><H><K><A><L><K><V><T><I><T><V><L><T><V><F><V><L><S><Q><F><P><Y><N><C><I><L><L><V><Q><T><I><D><A><Y><A><M><F><I><S><N><C><A><V><S><T><N><I><D><I><C><F><Q><V><T><Q><T><I><A><F><F><H><S><C><L><N><P><V><L><Y><V><F><V><G><E><R><F><R><R><D><L><V><K><T><L><K><N><L><G><C><I><S><Q><A><Q><W><V><S><F><T><R><R><E><G><S><L><K><L><S><S><M><L><L><E><T><T><S><G><A><L><S><L>
(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.<BOP>
P51686
Q9UGF7
O12D3_HUMAN
Olfactory receptor OR6-27
Homo
<M><E><N><V><T><T><M><N><E><F><L><L><L><G><L><T><G><V><Q><E><L><Q><P><F><F><F><G><I><F><L><I><I><Y><L><I><N><L><I><G><N><G><S><I><L><V><M><V><V><L><E><P><Q><L><H><S><P><M><Y><F><F><L><G><N><L><S><C><L><D><I><S><Y><S><S><V><T><L><P><K><L><L><V><N><L><V><C><S><R><R><A><I><S><F><L><G><C><I><T><Q><L><H><F><F><H><F><L><G><S><T><E><A><I><L><L><A><I><M><A><F><D><R><F><V><A><I><C><N><P><L><R><Y><T><V><I><M><N><P><Q><V><C><I><L><L><A><A><A><A><W><L><I><S><F><F><Y><A><L><M><H><S><V><M><T><A><H><L><S><F><C><G><S><Q><K><L><N><H><F><F><Y><D><V><K><P><L><L><E><L><A><C><S><D><T><L><L><N><Q><W><L><L><S><I><V><T><G><S><I><S><M><G><A><F><F><L><T><L><L><S><C><F><Y><V><I><G><F><L><L><F><K><N><R><S><C><R><I><L><H><K><A><L><S><T><C><A><S><H><F><M><V><V><C><L><F><Y><G><P><V><G><F><T><Y><I><R><P><A><S><A><T><S><M><I><Q><D><R><I><M><A><I><M><Y><S><A><V><T><P><V><L><N><P><L><I><Y><T><L><R><N><K><E><V><M><M><A><L><K><K><I><F><G><R><K><L><F><K><D><W><Q><Q><H><H>
Odorant receptor.<BOP>
Q9UGF7
Q8NGI0
O52N2_HUMAN
Olfactory receptor OR11-57
Homo
<M><S><G><D><N><S><S><S><L><T><P><G><F><F><I><L><N><G><V><P><G><L><E><A><T><H><I><W><I><S><L><P><F><C><F><M><Y><I><I><A><V><V><G><N><C><G><L><I><C><L><I><S><H><E><E><A><L><H><R><P><M><Y><Y><F><L><A><L><L><S><F><T><D><V><T><L><C><T><T><M><V><P><N><M><L><C><I><F><W><F><N><L><K><E><I><D><F><N><A><C><L><A><Q><M><F><F><V><H><M><L><T><G><M><E><S><G><V><L><M><L><M><A><L><D><R><Y><V><A><I><C><Y><P><L><R><Y><A><T><I><L><T><N><P><V><I><A><K><A><G><L><A><T><F><L><R><N><V><M><L><I><I><P><F><T><L><L><T><K><R><L><P><Y><C><R><G><N><F><I><P><H><T><Y><C><D><H><M><S><V><A><K><V><S><C><G><N><F><K><V><N><A><I><Y><G><L><M><V><A><L><L><I><G><V><F><D><I><C><C><I><S><V><S><Y><T><M><I><L><Q><A><V><M><S><L><S><S><A><D><A><R><H><K><A><F><S><T><C><T><S><H><M><C><S><I><V><I><T><Y><V><A><A><F><F><T><F><F><T><H><R><F><V><G><H><N><I><P><N><H><I><H><I><I><V><A><N><L><Y><L><L><L><P><P><T><M><N><P><I><V><Y><G><V><K><T><K><Q><I><Q><E><G><V><I><K><F><L><L><G><D><K><V><S><F><T><Y><D><K>
Odorant receptor.<BOP>
Q8NGI0
Q08830
FGL1_HUMAN
Liver fibrinogen-related protein 1
Homo
<M><A><K><V><F><S><F><I><L><V><T><T><A><L><T><M><G><R><E><I><S><A><L><E><D><C><A><Q><E><Q><M><R><L><R><A><Q><V><R><L><L><E><T><R><V><K><Q><Q><Q><V><K><I><K><Q><L><L><Q><E><N><E><V><Q><F><L><D><K><G><D><E><N><T><V><I><D><L><G><S><K><R><Q><Y><A><D><C><S><E><I><F><N><D><G><Y><K><L><S><G><F><Y><K><I><K><P><L><Q><S><P><A><E><F><S><V><Y><C><D><M><S><D><G><G><G><W><T><V><I><Q><R><R><S><D><G><S><E><N><F><N><R><G><W><K><D><Y><E><N><G><F><G><N><F><V><Q><K><H><G><E><Y><W><L><G><N><K><N><L><H><F><L><T><T><Q><E><D><Y><T><L><K><I><D><L><A><D><F><E><K><N><S><R><Y><A><Q><Y><K><N><F><K><V><G><D><E><K><N><F><Y><E><L><N><I><G><E><Y><S><G><T><A><G><D><S><L><A><G><N><F><H><P><E><V><Q><W><W><A><S><H><Q><R><M><K><F><S><T><W><D><R><D><H><D><N><Y><E><G><N><C><A><E><E><D><Q><S><G><W><W><F><N><R><C><H><S><A><N><L><N><G><V><Y><Y><S><G><P><Y><T><A><K><T><D><N><G><I><V><W><Y><T><W><H><G><W><W><Y><S><L><K><S><V><V><M><K><I><R><P><N><D><F><I><P><N><V><I>
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 . Responsible for LAG3 T-cell inhibitory function . Binds LAG3 independently from MHC class II (MHC-II) . Secreted by, and promotes growth of, hepatocytes .<BOP>
Q08830
Q9BRK4
LZTS2_HUMAN
Protein LAPSER1
Homo
<M><A><I><V><Q><T><L><P><V><P><L><E><P><A><P><E><A><A><T><A><P><Q><A><P><V><M><G><S><V><S><S><L><I><S><G><R><P><C><P><G><G><P><A><P><P><R><H><H><G><P><P><G><P><T><F><F><R><Q><Q><D><G><L><L><R><G><G><Y><E><A><Q><E><P><L><C><P><A><V><P><P><R><K><A><V><P><V><T><S><F><T><Y><I><N><E><D><F><R><T><E><S><P><P><S><P><S><S><D><V><E><D><A><R><E><Q><R><A><H><N><A><H><L><R><G><P><P><P><K><L><I><P><V><S><G><K><L><E><K><N><M><E><K><I><L><I><R><P><T><A><F><K><P><V><L><P><K><P><R><G><A><P><S><L><P><S><F><M><G><P><R><A><T><G><L><S><G><S><Q><G><S><L><T><Q><L><F><G><G><P><A><S><S><S><S><S><S><S><S><S><S><A><A><D><K><P><L><A><F><S><G><W><A><S><G><C><P><S><G><T><L><S><D><S><G><R><N><S><L><S><S><L><P><T><Y><S><T><G><G><A><E><P><T><T><S><S><P><G><G><H><L><P><S><H><G><S><G><R><G><A><L><P><G><P><A><R><G><V><P><T><G><P><S><H><S><D><S><G><R><S><S><S><S><K><S><T><G><S><L><G><G><R><V><A><G><G><L><L><G><S><G><T><R><A><S><P><D><S><S><S><C><G><E><R><S><P><P><P><P><P><P><P><P><S><D><E><A><L><L><H><C><V><L><E><G><K><L><R><D><R><E><A><E><L><Q><Q><L><R><D><S><L><D><E><N><E><A><T><M><C><Q><A><Y><E><E><R><Q><R><H><W><Q><R><E><R><E><A><L><R><E><D><C><A><A><Q><A><Q><R><A><Q><R><A><Q><Q><L><L><Q><L><Q><V><F><Q><L><Q><Q><E><K><R><Q><L><Q><D><D><F><A><Q><L><L><Q><E><R><E><Q><L><E><R><R><C><A><T><L><E><R><E><Q><R><E><L><G><P><R><L><E><E><T><K><W><E><V><C><Q><K><S><G><E><I><S><L><L><K><Q><Q><L><K><E><S><Q><A><E><L><V><Q><K><G><S><E><L><V><A><L><R><V><A><L><R><E><A><R><A><T><L><R><V><S><E><G><R><A><R><G><L><Q><E><A><A><R><A><R><E><L><E><L><E><A><C><S><Q><E><L><Q><R><H><R><Q><E><A><E><Q><L><R><E><K><A><G><Q><L><D><A><E><A><A><G><L><R><E><P><P><V><P><P><A><T><A><D><P><F><L><L><A><E><S><D><E><A><K><V><Q><R><A><A><A><G><V><G><G><S><L><R><A><Q><V><E><R><L><R><V><E><L><Q><R><E><R><R><R><G><E><E><Q><R><D><S><F><E><G><E><R><L><A><W><Q><A><E><K><E><Q><V><I><R><Y><Q><K><Q><L><Q><H><N><Y><I><Q><M><Y><R><R><N><R><Q><L><E><Q><E><L><Q><Q><L><S><L><E><L><E><A><R><E><L><A><D><L><G><L><A><E><Q><A><P><C><I><C><L><E><E><I><T><A><T><E><I>
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.<BOP>
Q9BRK4
Q9H4A5
GLP3L_HUMAN
GPP34-related protein
Homo
<M><T><T><L><T><H><R><A><R><R><T><E><I><S><K><N><S><E><K><K><M><E><S><E><E><D><S><N><W><E><K><S><P><D><N><E><D><S><G><D><S><K><D><I><R><L><T><L><M><E><E><V><L><L><L><G><L><K><D><K><E><G><Y><T><S><F><W><N><D><C><I><S><S><G><L><R><G><G><I><L><I><E><L><A><M><R><G><R><I><Y><L><E><P><P><T><M><R><K><K><R><L><L><D><R><K><V><L><L><K><S><D><S><P><T><G><D><V><L><L><D><E><T><L><K><H><I><K><A><T><E><P><T><E><T><V><Q><T><W><I><E><L><L><T><G><E><T><W><N><P><F><K><L><Q><Y><Q><L><R><N><V><R><E><R><I><A><K><N><L><V><E><K><G><I><L><T><T><E><K><Q><N><F><L><L><F><D><M><T><T><H><P><V><T><N><T><T><E><K><Q><R><L><V><K><K><L><Q><D><S><V><L><E><R><W><V><N><D><P><Q><R><M><D><K><R><T><L><A><L><L><V><L><A><H><S><S><D><V><L><E><N><V><F><S><S><L><T><D><D><K><Y><D><V><A><M><N><R><A><K><D><L><V><E><L><D><P><E><V><E><G><T><K><P><S><A><T><E><M><I><W><A><V><L><A><A><F><N><K><S>
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.<BOP>
Q9H4A5
Q9Y3R4
NEUR2_HUMAN
N-acetyl-alpha-neuraminidase 2
Homo
<M><A><S><L><P><V><L><Q><K><E><S><V><F><Q><S><G><A><H><A><Y><R><I><P><A><L><L><Y><L><P><G><Q><Q><S><L><L><A><F><A><E><Q><R><A><S><K><K><D><E><H><A><E><L><I><V><L><R><R><G><D><Y><D><A><P><T><H><Q><V><Q><W><Q><A><Q><E><V><V><A><Q><A><R><L><D><G><H><R><S><M><N><P><C><P><L><Y><D><A><Q><T><G><T><L><F><L><F><F><I><A><I><P><G><Q><V><T><E><Q><Q><Q><L><Q><T><R><A><N><V><T><R><L><C><Q><V><T><S><T><D><H><G><R><T><W><S><S><P><R><D><L><T><D><A><A><I><G><P><A><Y><R><E><W><S><T><F><A><V><G><P><G><H><C><L><Q><L><H><D><R><A><R><S><L><V><V><P><A><Y><A><Y><R><K><L><H><P><I><Q><R><P><I><P><S><A><F><C><F><L><S><H><D><H><G><R><T><W><A><R><G><H><F><V><A><Q><D><T><L><E><C><Q><V><A><E><V><E><T><G><E><Q><R><V><V><T><L><N><A><R><S><H><L><R><A><R><V><Q><A><Q><S><T><N><D><G><L><D><F><Q><E><S><Q><L><V><K><K><L><V><E><P><P><P><Q><G><C><Q><G><S><V><I><S><F><P><S><P><R><S><G><P><G><S><P><A><Q><W><L><L><Y><T><H><P><T><H><S><W><Q><R><A><D><L><G><A><Y><L><N><P><R><P><P><A><P><E><A><W><S><E><P><V><L><L><A><K><G><S><C><A><Y><S><D><L><Q><S><M><G><T><G><P><D><G><S><P><L><F><G><C><L><Y><E><A><N><D><Y><E><E><I><V><F><L><M><F><T><L><K><Q><A><F><P><A><E><Y><L><P><Q>
Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides . Recognizes sialyl linkage positions of the glycan moiety as well as the supramolecular organization of the sialoglycoconjugate. Displays preference for alpha-(2->3)-sialylated GD1a and GT1B gangliosides over alpha-(2->8)-sialylated GD1b, in both monomeric forms and micelles. Hydrolyzes monomeric GM1 ganglioside, but has no activity toward the miscellar form . Has lower sialidase activity for glycoproteins such as fetuin and TF/transferrin that carry a mixture of alpha-(2->3) and alpha-(2->6)-sialyl linkages. Cleaves milk oligosaccharide alpha-(2->3)-sialyllactose, but is inactive toward alpha-(2->6)-sialyllactose isomer. Has no
Q9Y3R4
P09525
ANXA4_HUMAN
Protein II
Homo
<M><A><T><K><G><G><T><V><K><A><A><S><G><F><N><A><M><E><D><A><Q><T><L><R><K><A><M><K><G><L><G><T><D><E><D><A><I><I><S><V><L><A><Y><R><N><T><A><Q><R><Q><E><I><R><T><A><Y><K><S><T><I><G><R><D><L><I><D><D><L><K><S><E><L><S><G><N><F><E><Q><V><I><V><G><M><M><T><P><T><V><L><Y><D><V><Q><E><L><R><R><A><M><K><G><A><G><T><D><E><G><C><L><I><E><I><L><A><S><R><T><P><E><E><I><R><R><I><S><Q><T><Y><Q><Q><Q><Y><G><R><S><L><E><D><D><I><R><S><D><T><S><F><M><F><Q><R><V><L><V><S><L><S><A><G><G><R><D><E><G><N><Y><L><D><D><A><L><V><R><Q><D><A><Q><D><L><Y><E><A><G><E><K><K><W><G><T><D><E><V><K><F><L><T><V><L><C><S><R><N><R><N><H><L><L><H><V><F><D><E><Y><K><R><I><S><Q><K><D><I><E><Q><S><I><K><S><E><T><S><G><S><F><E><D><A><L><L><A><I><V><K><C><M><R><N><K><S><A><Y><F><A><E><K><L><Y><K><S><M><K><G><L><G><T><D><D><N><T><L><I><R><V><M><V><S><R><A><E><I><D><M><L><D><I><R><A><H><F><K><R><L><Y><G><K><S><L><Y><S><F><I><K><G><D><T><S><G><D><Y><R><K><V><L><L><V><L><C><G><G><D><D>
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.<BOP>
P09525
O15354
GPR37_HUMAN
Parkin-associated endothelin receptor-like receptor
Homo
<M><R><A><P><G><A><L><L><A><R><M><S><R><L><L><L><L><L><L><L><K><V><S><A><S><S><A><L><G><V><A><P><A><S><R><N><E><T><C><L><G><E><S><C><A><P><T><V><I><Q><R><R><G><R><D><A><W><G><P><G><N><S><A><R><D><V><L><R><A><R><A><P><R><E><E><Q><G><A><A><F><L><A><G><P><S><W><D><L><P><A><A><P><G><R><D><P><A><A><G><R><G><A><E><A><S><A><A><G><P><P><G><P><P><T><R><P><P><G><P><W><R><W><K><G><A><R><G><Q><E><P><S><E><T><L><G><R><G><N><P><T><A><L><Q><L><F><L><Q><I><S><E><E><E><E><K><G><P><R><G><A><G><I><S><G><R><S><Q><E><Q><S><V><K><T><V><P><G><A><S><D><L><F><Y><W><P><R><R><A><G><K><L><Q><G><S><H><H><K><P><L><S><K><T><A><N><G><L><A><G><H><E><G><W><T><I><A><L><P><G><R><A><L><A><Q><N><G><S><L><G><E><G><I><H><E><P><G><G><P><R><R><G><N><S><T><N><R><R><V><R><L><K><N><P><F><Y><P><L><T><Q><E><S><Y><G><A><Y><A><V><M><C><L><S><V><V><I><F><G><T><G><I><I><G><N><L><A><V><M><C><I><V><C><H><N><Y><Y><M><R><S><I><S><N><S><L><L><A><N><L><A><F><W><D><F><L><I><I><F><F><C><L><P><L><V><I><F><H><E><L><T><K><K><W><L><L><E><D><F><S><C><K><I><V><P><Y><I><E><V><A><S><L><G><V><T><T><F><T><L><C><A><L><C><I><D><R><F><R><A><A><T><N><V><Q><M><Y><Y><E><M><I><E><N><C><S><S><T><T><A><K><L><A><V><I><W><V><G><A><L><L><L><A><L><P><E><V><V><L><R><Q><L><S><K><E><D><L><G><F><S><G><R><A><P><A><E><R><C><I><I><K><I><S><P><D><L><P><D><T><I><Y><V><L><A><L><T><Y><D><S><A><R><L><W><W><Y><F><G><C><Y><F><C><L><P><T><L><F><T><I><T><C><S><L><V><T><A><R><K><I><R><K><A><E><K><A><C><T><R><G><N><K><R><Q><I><Q><L><E><S><Q><M><N><C><T><V><V><A><L><T><I><L><Y><G><F><C><I><I><P><E><N><I><C><N><I><V><T><A><Y><M><A><T><G><V><S><Q><Q><T><M><D><L><L><N><I><I><S><Q><F><L><L><F><F><K><S><C><V><T><P><V><L><L><F><C><L><C><K><P><F><S><R><A><F><M><E><C><C><C><C><C><C><E><E><C><I><Q><K><S><S><T><V><T><S><D><D><N><D><N><E><Y><T><T><E><L><E><L><S><P><F><S><T><I><R><R><E><M><S><T><F><A><S><V><G><T><H><C>
Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.<BOP>
O15354
O75604
UBP2_HUMAN
Ubiquitin-specific-processing protease 2
Homo
<M><S><Q><L><S><S><T><L><K><R><Y><T><E><S><A><R><Y><T><D><A><H><Y><A><K><S><G><Y><G><A><Y><T><P><S><S><Y><G><A><N><L><A><A><S><L><L><E><K><E><K><L><G><F><K><P><V><P><T><S><S><F><L><T><R><P><R><T><Y><G><P><S><S><L><L><D><Y><D><R><G><R><P><L><L><R><P><D><I><T><G><G><G><K><R><A><E><S><Q><T><R><G><T><E><R><P><L><G><S><G><L><S><G><G><S><G><F><P><Y><G><V><T><N><N><C><L><S><Y><L><P><I><N><A><Y><D><Q><G><V><T><L><T><Q><K><L><D><S><Q><S><D><L><A><R><D><F><S><S><L><R><T><S><D><S><Y><R><I><D><P><R><N><L><G><R><S><P><M><L><A><R><T><R><K><E><L><C><T><L><Q><G><L><Y><Q><T><A><S><C><P><E><Y><L><V><D><Y><L><E><N><Y><G><R><K><G><S><A><S><Q><V><P><S><Q><A><P><P><S><R><V><P><E><I><I><S><P><T><Y><R><P><I><G><R><Y><T><L><W><E><T><G><K><G><Q><A><P><G><P><S><R><S><S><S><P><G><R><D><G><M><N><S><K><S><A><Q><G><L><A><G><L><R><N><L><G><N><T><C><F><M><N><S><I><L><Q><C><L><S><N><T><R><E><L><R><D><Y><C><L><Q><R><L><Y><M><R><D><L><H><H><G><S><N><A><H><T><A><L><V><E><E><F><A><K><L><I><Q><T><I><W><T><S><S><P><N><D><V><V><S><P><S><E><F><K><T><Q><I><Q><R><Y><A><P><R><F><V><G><Y><N><Q><Q><D><A><Q><E><F><L><R><F><L><L><D><G><L><H><N><E><V><N><R><V><T><L><R><P><K><S><N><P><E><N><L><D><H><L><P><D><D><E><K><G><R><Q><M><W><R><K><Y><L><E><R><E><D><S><R><I><G><D><L><F><V><G><Q><L><K><S><S><L><T><C><T><D><C><G><Y><C><S><T><V><F><D><P><F><W><D><L><S><L><P><I><A><K><R><G><Y><P><E><V><T><L><M><D><C><M><R><L><F><T><K><E><D><V><L><D><G><D><E><K><P><T><C><C><R><C><R><G><R><K><R><C><I><K><K><F><S><I><Q><R><F><P><K><I><L><V><L><H><L><K><R><F><S><E><S><R><I><R><T><S><K><L><T><T><F><V><N><F><P><L><R><D><L><D><L><R><E><F><A><S><E><N><T><N><H><A><V><Y><N><L><Y><A><V><S><N><H><S><G><T><T><M><G><G><H><Y><T><A><Y><C><R><S><P><G><T><G><E><W><H><T><F><N><D><S><S><V><T><P><M><S><S><S><Q><V><R><T><S><D><A><Y><L><L><F><Y><E><L><A><S><P><P><S><R><M>
Circadian clock output effector that regulates Ca(2+) absorption in the small intestine. Probably functions by regulating protein levels of the membrane scaffold protein NHERF4 in a rhythmic manner, and is therefore likely to control Ca(2+) membrane permeability mediated by the Ca(2+) channel TRPV6 in the intestine.<BOP>
O75604
P78380
OLR1_HUMAN
Oxidized low-density lipoprotein receptor 1, soluble form
Homo
<M><T><F><D><D><L><K><I><Q><T><V><K><D><Q><P><D><E><K><S><N><G><K><K><A><K><G><L><Q><F><L><Y><S><P><W><W><C><L><A><A><A><T><L><G><V><L><C><L><G><L><V><V><T><I><M><V><L><G><M><Q><L><S><Q><V><S><D><L><L><T><Q><E><Q><A><N><L><T><H><Q><K><K><K><L><E><G><Q><I><S><A><R><Q><Q><A><E><E><A><S><Q><E><S><E><N><E><L><K><E><M><I><E><T><L><A><R><K><L><N><E><K><S><K><E><Q><M><E><L><H><H><Q><N><L><N><L><Q><E><T><L><K><R><V><A><N><C><S><A><P><C><P><Q><D><W><I><W><H><G><E><N><C><Y><L><F><S><S><G><S><F><N><W><E><K><S><Q><E><K><C><L><S><L><D><A><K><L><L><K><I><N><S><T><A><D><L><D><F><I><Q><Q><A><I><S><Y><S><S><F><P><F><W><M><G><L><S><R><R><N><P><S><Y><P><W><L><W><E><D><G><S><P><L><M><P><H><L><F><R><V><R><G><A><V><S><Q><T><Y><P><S><G><T><C><A><Y><I><Q><R><G><A><V><Y><A><E><N><C><I><L><A><A><F><S><I><C><Q><K><K><A><N><L><R><A><Q>
(Microbial infection) May serve as a receptor for adhesin A variant 3 (nadA) of N.meningitidis.<BOP>
P78380
P55199
ELL_HUMAN
Eleven-nineteen lysine-rich leukemia protein
Homo
<M><A><A><L><K><E><D><R><S><Y><G><L><S><C><G><R><V><S><D><G><S><K><V><S><V><F><H><V><K><L><T><D><S><A><L><R><A><F><E><S><Y><R><A><R><Q><D><S><V><S><L><R><P><S><I><R><F><Q><G><S><Q><G><H><I><S><I><P><Q><P><D><C><P><A><E><A><R><T><F><S><F><Y><L><S><N><I><G><R><D><N><P><Q><G><S><F><D><C><I><Q><Q><Y><V><S><S><H><G><E><V><H><L><D><C><L><G><S><I><Q><D><K><I><T><V><C><A><T><D><D><S><Y><Q><K><A><R><Q><S><M><A><Q><A><E><E><E><T><R><S><R><S><A><I><V><I><K><A><G><G><R><Y><L><G><K><K><V><Q><F><R><K><P><A><P><G><A><T><D><A><V><P><S><R><K><R><A><T><P><I><N><L><A><S><A><I><R><K><S><G><A><S><A><V><S><G><G><S><G><V><S><Q><R><P><F><R><D><R><V><L><H><L><L><A><L><R><P><Y><R><K><A><E><L><L><L><R><L><Q><K><D><G><L><T><Q><A><D><K><D><A><L><D><G><L><L><Q><Q><V><A><N><M><S><A><K><D><G><T><C><T><L><Q><D><C><M><Y><K><D><V><Q><K><D><W><P><G><Y><S><E><G><D><Q><Q><L><L><K><R><V><L><V><R><K><L><C><Q><P><Q><S><T><G><S><L><L><G><D><P><A><A><S><S><P><P><G><E><R><G><R><S><A><S><P><P><Q><K><R><L><Q><P><P><D><F><I><D><P><L><A><N><K><K><P><R><I><S><H><F><T><Q><R><A><Q><P><A><V><N><G><K><L><G><V><P><N><G><R><E><A><L><L><P><T><P><G><P><P><A><S><T><D><T><L><S><S><S><T><H><L><P><P><R><L><E><P><P><R><A><H><D><P><L><A><D><V><S><N><D><L><G><H><S><G><R><D><C><E><H><G><E><A><A><A><P><A><P><T><V><R><L><G><L><P><L><L><T><D><C><A><Q><P><S><R><P><H><G><S><P><S><R><S><K><P><K><K><K><S><K><K><H><K><D><K><E><R><A><A><E><D><K><P><R><A><Q><L><P><D><C><A><P><A><T><H><A><T><P><G><A><P><A><D><T><P><G><L><N><G><T><C><S><V><S><S><V><P><T><S><T><S><E><T><P><D><Y><L><L><K><Y><A><A><I><S><S><S><E><Q><R><Q><S><Y><K><N><D><F><N><A><E><Y><S><E><Y><R><D><L><H><A><R><I><E><R><I><T><R><R><F><T><Q><L><D><A><Q><L><R><Q><L><S><Q><G><S><E><E><Y><E><T><T><R><G><Q><I><L><Q><E><Y><R><K><I><K><K><T><N><T><N><Y><S><Q><E><K><H><R><C><E><Y><L><H><S><K><L><A><H><I><K><R><L><I><A><E><Y><D><Q><R><Q><L><Q><A><W><P>
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III . Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription . ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.<BOP>
P55199
Q8NH16
OR2L2_HUMAN
Olfactory receptor 2L4
Homo
<M><E><N><Y><N><Q><T><S><T><D><F><I><L><L><G><L><F><P><Q><S><R><I><G><L><F><V><F><T><L><I><F><L><I><F><L><M><A><L><I><G><N><L><S><M><I><L><L><I><F><L><D><I><H><L><H><T><P><M><Y><F><L><L><S><Q><L><S><L><I><D><L><N><Y><I><S><T><I><V><P><K><M><V><Y><D><F><L><Y><G><N><K><S><I><S><F><T><G><C><G><I><Q><S><F><F><F><L><T><L><A><V><A><E><G><L><L><L><T><S><M><A><Y><D><R><Y><V><A><I><C><F><P><L><H><Y><P><I><R><I><S><K><R><V><C><V><M><M><I><T><G><S><W><M><I><S><S><I><N><S><C><A><H><T><V><Y><A><L><C><I><P><Y><C><K><S><R><A><I><N><H><F><F><C><D><V><P><A><M><L><T><L><A><C><T><D><T><W><V><Y><E><S><T><V><F><L><S><S><T><I><F><L><V><L><P><F><T><G><I><A><C><S><Y><G><R><V><L><L><A><V><Y><R><M><H><S><A><E><G><R><K><K><A><Y><S><T><C><S><T><H><L><T><V><V><S><F><Y><Y><A><P><F><A><Y><T><Y><V><R><P><R><S><L><R><S><P><T><E><D><K><I><L><A><V><F><Y><T><I><L><T><P><M><L><N><P><I><I><Y><S><L><R><N><K><E><V><M><G><A><L><T><Q><V><I><Q><K><I><F><S><V><K><M>
Odorant receptor.<BOP>
Q8NH16
A6NC78
GOG8I_HUMAN
Golgin subfamily A member 8I pseudogene
Homo
<M><A><E><E><T><Q><H><N><K><L><A><A><A><K><K><K><L><K><E><Y><W><Q><K><N><S><P><R><V><P><A><G><A><N><R><N><R><K><T><N><G><S><I><P><Q><T><A><T><S><G><G><C><Q><P><P><G><D><S><A><T><G><F><H><R><E><G><P><T><S><S><A><T><L><K><D><L><E><S><P><C><Q><E><R><A><V><V><L><D><S><R><S><V><E><I><S><Q><L><K><N><T><I><K><S><L><K><Q><Q><K><K><Q><V><E><H><Q><L><E><E><E><K><K><A><N><I><K><K><Q><K><A><K><R><V><L><E><V><Q><I><Q><T><L><N><I><Q><K><E><E><L><N><T><D><L><Y><H><M><K><R><S><L><R><Y><F><E><E><K><S><K><D><L><A><V><R><L><Q><H><S><L><Q><R><K><G><E><L><E><S><V><L><S><D><V><M><A><T><Q><K><K><K><A><N><Q><L><S><S><P><S><K><A><G><T><E><W><K><L><E><Q><S><M><R><E><E><A><L><L><K><V><Q><L><T><Q><L><K><E><S><F><Q><Q><L><Q><L><E><R><H><E><Y><A><E><H><L><K><G><E><R><A><R><W><Q><Q><R><M><R><K><M><S><Q><E><I><C><T><L><K><K><E><K><Q><Q><D><M><R><R><V><E><K><L><E><R><S><L><S><K><L><K><N><Q><M><A><E><P><L><P><P><E><P><P><A><V><P><S><E><V><E><L><Q><H><L><R><K><E><L><E><R><V><A><G><A><L><Q><A><Q><V><K><N><N><Q><R><I><S><L><L><N><R><G><Q><E><E><R><I><R><E><Q><E><E><R><L><R><K><Q><E><E><R><I><Q><E><Q><H><K><S><L><Q><Q><L><A><K><P><Q><S><V><F><E><E><P><N><N><E><N><K><S><A><L><Q><L><E><Q><Q><V><K><E><L><Q><E><K><L><G><E><E><H><L><E><A><A><S><Q><Q><N><Q><Q><L><T><A><Q><L><S><L><M><A><L><P><G><E><G><H><G><G><E><H><L><D><S><E><G><E><E><A><P><Q><P><M><P><S><V><P><E><D><L><E><S><R><E><A><M><S><S><F><M><D><H><L><E><E><K><A><D><L><S><E><L><V><K><K><K><E><L><C><F><I><H><H><W><R><E><R><C><H><Q><K><T><H><H><L><L><S><E><P><G><G><R><A><K><D><A><A><L><G><G><G><H><H><Q><A><G><A><Q><G><G><D><E><G><E><A><A><G><A><A><A><D><G><I><A><A><Y><S><N><Y><N><N><G><H><R><K><F><L><A><A><A><H><N><P><A><D><E><P><G><P><G><A><P><A><P><Q><E><L><G><A><A><D><K><H><G><D><L><C><E><V><S><L><T><S><S><A><Q><G><E><A><R><E><D><P><L><L><D><K><P><T><A><Q><P><I><V><Q><D><H><Q><E><H><P><G><L><G><S><N><C><C><V><P><F><F><C><W><A><W><L><P><R><R><R><R>
May be involved in maintaining Golgi structure.<BOP>
A6NC78
Q96R45
OR2A7_HUMAN
Olfactory receptor OR7-18
Homo
<M><G><D><N><I><T><S><I><T><E><F><L><L><L><G><F><P><V><G><P><R><I><Q><M><L><L><F><G><L><F><S><L><F><Y><V><F><T><L><L><G><N><G><T><I><L><G><L><I><S><L><D><S><R><L><H><A><P><M><Y><F><F><L><S><H><L><A><V><V><D><I><A><Y><A><C><N><T><V><P><R><M><L><V><N><L><L><H><P><A><K><P><I><S><F><A><G><R><M><M><Q><T><F><L><F><S><T><F><A><V><T><E><C><L><L><L><V><V><M><S><Y><D><L><Y><V><A><I><C><H><P><L><R><Y><L><A><I><M><T><W><R><V><C><I><T><L><A><V><T><S><W><T><T><G><V><L><L><S><L><I><H><L><V><L><L><L><P><L><P><F><C><R><P><Q><K><I><Y><H><F><F><C><E><I><L><A><V><L><K><L><A><C><A><D><T><H><I><N><E><N><M><V><L><A><G><A><I><S><G><L><V><G><P><L><S><T><I><V><V><S><Y><M><C><I><L><C><A><I><L><Q><I><Q><S><R><E><V><Q><R><K><A><F><C><T><C><F><S><H><L><C><V><I><G><L><F><Y><G><T><A><I><I><M><Y><V><G><P><R><Y><G><N><P><K><E><Q><K><K><Y><L><L><L><F><H><S><L><F><N><P><M><L><N><P><L><I><C><S><L><R><N><S><E><V><K><N><T><L><K><R><V><L><G><V><E><R><A><L>
Odorant receptor.<BOP>
Q96R45
Q8NFW8
NEUA_HUMAN
CMP-N-acetylneuraminic acid synthase
Homo
<M><D><S><V><E><K><G><A><A><T><S><V><S><N><P><R><G><R><P><S><R><G><R><P><P><K><L><Q><R><N><S><R><G><G><Q><G><R><G><V><E><K><P><P><H><L><A><A><L><I><L><A><R><G><G><S><K><G><I><P><L><K><N><I><K><H><L><A><G><V><P><L><I><G><W><V><L><R><A><A><L><D><S><G><A><F><Q><S><V><W><V><S><T><D><H><D><E><I><E><N><V><A><K><Q><F><G><A><Q><V><H><R><R><S><S><E><V><S><K><D><S><S><T><S><L><D><A><I><I><E><F><L><N><Y><H><N><E><V><D><I><V><G><N><I><Q><A><T><S><P><C><L><H><P><T><D><L><Q><K><V><A><E><M><I><R><E><E><G><Y><D><S><V><F><S><V><V><R><R><H><Q><F><R><W><S><E><I><Q><K><G><V><R><E><V><T><E><P><L><N><L><N><P><A><K><R><P><R><R><Q><D><W><D><G><E><L><Y><E><N><G><S><F><Y><F><A><K><R><H><L><I><E><M><G><Y><L><Q><G><G><K><M><A><Y><Y><E><M><R><A><E><H><S><V><D><I><D><V><D><I><D><W><P><I><A><E><Q><R><V><L><R><Y><G><Y><F><G><K><E><K><L><K><E><I><K><L><L><V><C><N><I><D><G><C><L><T><N><G><H><I><Y><V><S><G><D><Q><K><E><I><I><S><Y><D><V><K><D><A><I><G><I><S><L><L><K><K><S><G><I><E><V><R><L><I><S><E><R><A><C><S><K><Q><T><L><S><S><L><K><L><D><C><K><M><E><V><S><V><S><D><K><L><A><V><V><D><E><W><R><K><E><M><G><L><C><W><K><E><V><A><Y><L><G><N><E><V><S><D><E><E><C><L><K><R><V><G><L><S><G><A><P><A><D><A><C><S><T><A><Q><K><A><V><G><Y><I><C><K><C><N><G><G><R><G><A><I><R><E><F><A><E><H><I><C><L><L><M><E><K><V><N><N><S><C><Q><K>
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).<BOP>
Q8NFW8
O75477
ERLN1_HUMAN
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Homo
<M><N><M><T><Q><A><R><V><L><V><A><A><V><V><G><L><V><A><V><L><L><Y><A><S><I><H><K><I><E><E><G><H><L><A><V><Y><Y><R><G><G><A><L><L><T><S><P><S><G><P><G><Y><H><I><M><L><P><F><I><T><T><F><R><S><V><Q><T><T><L><Q><T><D><E><V><K><N><V><P><C><G><T><S><G><G><V><M><I><Y><I><D><R><I><E><V><V><N><M><L><A><P><Y><A><V><F><D><I><V><R><N><Y><T><A><D><Y><D><K><T><L><I><F><N><K><I><H><H><E><L><N><Q><F><C><S><A><H><T><L><Q><E><V><Y><I><E><L><F><D><Q><I><D><E><N><L><K><Q><A><L><Q><K><D><L><N><L><M><A><P><G><L><T><I><Q><A><V><R><V><T><K><P><K><I><P><E><A><I><R><R><N><F><E><L><M><E><A><E><K><T><K><L><L><I><A><A><Q><K><Q><K><V><V><E><K><E><A><E><T><E><R><K><K><A><V><I><E><A><E><K><I><A><Q><V><A><K><I><R><F><Q><Q><K><V><M><E><K><E><T><E><K><R><I><S><E><I><E><D><A><A><F><L><A><R><E><K><A><K><A><D><A><E><Y><Y><A><A><H><K><Y><A><T><S><N><K><H><K><L><T><P><E><Y><L><E><L><K><K><Y><Q><A><I><A><S><N><S><K><I><Y><F><G><S><N><I><P><N><M><F><V><D><S><S><C><A><L><K><Y><S><D><I><R><T><G><R><E><S><S><L><P><S><K><E><A><L><E><P><S><G><E><N><V><I><Q><N><K><E><S><T><G>
(Microbial infection) Required early in hepatitis C virus (HCV) infection to initiate RNA replication, and later in the infection to support infectious virus production.<BOP>
O75477
Q6ZV89
SH2D5_HUMAN
SH2 domain-containing protein 5
Homo
<M><Q><K><A><G><A><G><G><R><R><A><S><D><C><G><L><A><P><H><R><P><R><C><I><T><K><F><A><Q><Y><V><G><S><F><P><V><D><D><L><D><T><Q><E><S><V><W><L><V><Q><Q><Q><L><W><A><L><K><D><C><P><R><R><R><A><V><I><L><K><F><S><L><Q><G><L><K><I><Y><S><G><E><G><E><V><L><L><M><A><H><A><L><R><R><I><L><Y><S><T><W><C><P><A><D><C><Q><F><A><F><M><A><R><N><P><R><S><P><A><S><K><L><F><C><H><L><F><V><G><S><Q><P><G><E><V><Q><I><L><H><L><L><L><C><R><S><F><Q><L><A><Y><L><L><Q><H><P><E><E><R><A><Q><P><E><P><C><P><G><P><T><G><E><V><P><L><K><P><L><S><S><S><G><G><L><V><R><E><P><F><G><R><D><Q><L><S><Q><N><V><H><A><L><V><S><F><R><R><L><P><A><E><G><L><V><G><S><G><K><E><L><P><E><S><E><G><R><A><R><H><A><R><L><G><N><P><Y><C><S><P><T><L><V><R><K><K><A><I><R><S><K><V><I><R><S><G><A><Y><R><G><C><T><Y><E><T><Q><L><Q><L><S><A><R><E><A><F><P><A><A><W><E><A><W><P><R><G><P><G><G><H><S><C><L><V><E><S><E><G><S><L><T><E><N><I><W><A><F><A><G><I><S><R><P><C><A><L><A><L><L><R><R><D><V><L><G><A><F><L><L><W><P><E><L><G><A><S><G><Q><W><C><L><S><V><R><T><Q><C><G><V><V><P><H><Q><V><F><R><N><H><L><G><R><Y><C><L><E><H><L><P><A><E><F><P><S><L><E><A><L><V><E><N><H><A><V><T><E><R><S><L><F><C><P><L><D><M><G><R><L><N><P><T><Y><E><E><Q><D><C><G><P><P><G><R><P><P><R><T><L><R><P><L><S><H><A><K><S><E><A><E><L><Q><G><L><G>
May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.<BOP>
Q6ZV89
P14920
OXDA_HUMAN
D-amino-acid oxidase
Homo
<M><R><V><V><V><I><G><A><G><V><I><G><L><S><T><A><L><C><I><H><E><R><Y><H><S><V><L><Q><P><L><D><I><K><V><Y><A><D><R><F><T><P><L><T><T><T><D><V><A><A><G><L><W><Q><P><Y><L><S><D><P><N><N><P><Q><E><A><D><W><S><Q><Q><T><F><D><Y><L><L><S><H><V><H><S><P><N><A><E><N><L><G><L><F><L><I><S><G><Y><N><L><F><H><E><A><I><P><D><P><S><W><K><D><T><V><L><G><F><R><K><L><T><P><R><E><L><D><M><F><P><D><Y><G><Y><G><W><F><H><T><S><L><I><L><E><G><K><N><Y><L><Q><W><L><T><E><R><L><T><E><R><G><V><K><F><F><Q><R><K><V><E><S><F><E><E><V><A><R><E><G><A><D><V><I><V><N><C><T><G><V><W><A><G><A><L><Q><R><D><P><L><L><Q><P><G><R><G><Q><I><M><K><V><D><A><P><W><M><K><H><F><I><L><T><H><D><P><E><R><G><I><Y><N><S><P><Y><I><I><P><G><T><Q><T><V><T><L><G><G><I><F><Q><L><G><N><W><S><E><L><N><N><I><Q><D><H><N><T><I><W><E><G><C><C><R><L><E><P><T><L><K><N><A><R><I><I><G><E><R><T><G><F><R><P><V><R><P><Q><I><R><L><E><R><E><Q><L><R><T><G><P><S><N><T><E><V><I><H><N><Y><G><H><G><G><Y><G><L><T><I><H><W><G><C><A><L><E><A><A><K><L><F><G><R><I><L><E><E><K><K><L><S><R><M><P><P><S><H><L>
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<BOP>
P14920
Q14542
S29A2_HUMAN
Solute carrier family 29 member 2
Homo
<M><A><R><G><D><A><P><R><D><S><Y><H><L><V><G><I><S><F><F><I><L><G><L><G><T><L><L><P><W><N><F><F><I><T><A><I><P><Y><F><Q><A><R><L><A><G><A><G><N><S><T><A><R><I><L><S><T><N><H><T><G><P><E><D><A><F><N><F><N><N><W><V><T><L><L><S><Q><L><P><L><L><L><F><T><L><L><N><S><F><L><Y><Q><C><V><P><E><T><V><R><I><L><G><S><L><L><A><I><L><L><L><F><A><L><T><A><A><L><V><K><V><D><M><S><P><G><P><F><F><S><I><T><M><A><S><V><C><F><I><N><S><F><S><A><V><L><Q><G><S><L><F><G><Q><L><G><T><M><P><S><T><Y><S><T><L><F><L><S><G><Q><G><L><A><G><I><F><A><A><L><A><M><L><L><S><M><A><S><G><V><D><A><E><T><S><A><L><G><Y><F><I><T><P><C><V><G><I><L><M><S><I><V><C><Y><L><S><L><P><H><L><K><F><A><R><Y><Y><L><A><N><K><S><S><Q><A><Q><A><Q><E><L><E><T><K><A><E><L><L><Q><S><D><E><N><G><I><P><S><S><P><Q><K><V><A><L><T><L><D><L><D><L><E><K><E><P><E><S><E><P><D><E><P><Q><K><P><G><K><P><S><V><F><T><V><F><Q><K><I><W><L><T><A><L><C><L><V><L><V><F><T><V><T><L><S><V><F><P><A><I><T><A><M><V><T><S><S><T><S><P><G><K><W><S><Q><F><F><N><P><I><C><C><F><L><L><F><N><I><M><D><W><L><G><R><S><L><T><S><Y><F><L><W><P><D><E><D><S><R><L><L><P><L><L><V><C><L><R><F><L><F><V><P><L><F><M><L><C><H><V><P><Q><R><S><R><L><P><I><L><F><P><Q><D><A><Y><F><I><T><F><M><L><L><F><A><V><S><N><G><Y><L><V><S><L><T><M><C><L><A><P><R><Q><V><L><P><H><E><R><E><V><A><G><A><L><M><T><F><F><L><A><L><G><L><S><C><G><A><S><L><S><F><L><F><K><A><L><L>
Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.<BOP>
Q14542
Q8NGN2
O10S1_HUMAN
Olfactory receptor OR11-279
Homo
<M><T><S><R><S><V><C><E><K><M><T><M><T><T><E><N><P><N><Q><T><V><V><S><H><F><F><L><E><G><L><R><Y><T><A><K><H><S><S><L><F><F><L><L><F><L><L><I><Y><S><I><T><V><A><G><N><L><L><I><L><L><T><V><G><S><D><S><H><L><S><L><P><M><Y><H><F><L><G><H><L><S><F><L><D><A><C><L><S><T><V><T><V><P><K><V><M><A><G><L><L><T><L><D><G><K><V><I><S><F><E><G><C><A><V><Q><L><Y><C><F><H><F><L><A><S><T><E><C><F><L><Y><T><V><M><A><Y><D><R><Y><L><A><I><C><Q><P><L><H><Y><P><V><A><M><N><R><R><M><C><A><E><M><A><G><I><T><W><A><I><G><A><T><H><A><A><I><H><T><S><L><T><F><R><L><L><Y><C><G><P><C><H><I><A><Y><F><F><C><D><I><P><P><V><L><K><L><A><C><T><D><T><T><I><N><E><L><V><M><L><A><S><I><G><I><V><A><A><G><C><L><I><L><I><V><I><S><Y><I><F><I><V><A><A><V><L><R><I><R><T><A><Q><G><R><Q><R><A><F><S><P><C><T><A><Q><L><T><G><V><L><L><Y><Y><V><P><P><V><C><I><Y><L><Q><P><R><S><S><E><A><G><A><G><A><P><A><V><F><Y><T><I><V><T><P><M><L><N><P><F><I><Y><T><L><R><N><K><E><V><K><H><A><L><Q><R><L><L><C><S><S><F><R><E><S><T><A><G><S><P><P><P>
Odorant receptor.<BOP>
Q8NGN2
P47888
OR3A3_HUMAN
Olfactory receptor OR17-22
Homo
<M><S><L><Q><K><L><M><E><P><E><A><G><T><N><R><T><A><V><A><E><F><I><L><L><G><L><V><Q><T><E><E><M><Q><P><V><V><F><V><L><L><L><F><A><Y><L><V><T><T><G><G><N><L><S><I><L><A><A><V><L><V><E><P><K><L><H><A><P><M><Y><F><F><L><G><N><L><S><V><L><D><V><G><C><I><T><V><T><V><P><A><M><L><G><R><L><L><S><H><K><S><T><I><S><Y><D><A><C><L><S><Q><L><F><F><F><H><L><L><A><G><M><D><C><F><L><L><T><A><M><A><Y><D><R><L><L><A><I><C><Q><P><L><T><Y><S><T><R><M><S><Q><T><V><Q><R><M><L><V><A><A><S><W><A><C><A><F><T><N><A><L><T><H><T><V><A><M><S><T><L><N><F><C><G><P><N><E><V><N><H><F><Y><C><D><L><P><Q><L><F><Q><L><S><C><S><S><T><Q><L><N><E><L><L><L><F><V><A><A><A><F><M><A><V><A><P><L><V><F><I><S><V><S><Y><A><H><V><V><A><A><V><L><Q><I><R><S><A><E><G><R><K><K><A><F><S><T><C><G><S><H><L><T><V><V><G><I><F><Y><G><T><G><V><F><S><Y><M><R><L><G><S><V><E><S><S><D><K><D><K><G><V><G><V><F><M><T><V><I><N><P><M><L><N><P><L><I><Y><S><L><R><N><T><D><V><Q><G><A><L><C><Q><L><L><V><G><K><R><S><L><T>
Odorant receptor.<BOP>
P47888
Q8NGF9
OR4X2_HUMAN
Olfactory receptor OR11-105
Homo
<M><T><E><F><I><F><L><V><L><S><P><N><Q><E><V><Q><R><V><C><F><V><I><F><L><F><L><Y><T><A><I><V><L><G><N><F><L><I><V><L><T><V><M><T><S><R><S><L><G><S><P><M><Y><F><F><L><S><Y><L><S><F><M><E><I><C><Y><S><S><A><T><A><P><K><L><I><S><D><L><L><A><E><R><K><V><I><S><W><W><G><C><M><A><Q><L><F><F><L><H><F><F><G><G><T><E><I><F><L><L><T><V><M><A><Y><D><H><Y><V><A><I><C><K><P><L><S><Y><T><T><I><M><N><W><Q><V><C><T><V><L><V><G><I><A><W><V><G><G><F><M><H><S><F><A><Q><I><L><L><I><F><H><L><L><F><C><G><P><N><V><I><N><H><Y><F><C><D><L><V><P><L><L><K><L><A><C><S><D><T><F><L><I><G><L><L><I><V><A><N><G><G><T><L><S><V><I><S><F><G><V><L><L><A><S><Y><M><V><I><L><L><H><L><R><T><W><S><S><E><G><W><C><K><A><L><S><T><C><G><S><H><F><A><V><V><I><L><F><F><G><P><C><V><F><N><S><L><R><P><S><T><T><L><P><I><D><K><M><V><A><V><F><Y><T><V><I><T><A><I><L><N><P><V><I><Y><S><L><R><N><A><E><M><R><K><A><M><K><R><L><W><I><R><T><L><R><L><N><E><K>
Odorant receptor.<BOP>
Q8NGF9
O75106
AOC2_HUMAN
Semicarbazide-sensitive amine oxidase
Homo
<M><H><L><K><I><V><L><A><F><L><A><L><S><L><I><T><I><F><A><L><A><Y><V><L><L><T><S><P><G><G><S><S><Q><P><P><H><C><P><S><V><S><H><R><A><Q><P><W><P><H><P><G><Q><S><Q><L><F><A><D><L><S><R><E><E><L><T><A><V><M><R><F><L><T><Q><R><L><G><P><G><L><V><D><A><A><Q><A><Q><P><S><D><N><C><I><F><S><V><E><L><Q><L><P><P><K><A><A><A><L><A><H><L><D><R><G><S><P><P><P><A><R><E><A><L><A><I><V><L><F><G><G><Q><P><Q><P><N><V><S><E><L><V><V><G><P><L><P><H><P><S><Y><M><R><D><V><T><V><E><R><H><G><G><P><L><P><Y><H><R><R><P><V><L><R><A><E><F><T><Q><M><W><R><H><L><K><E><V><E><L><P><K><A><P><I><F><L><S><S><T><F><N><Y><N><G><S><T><L><A><A><V><H><A><T><P><R><G><L><R><S><G><D><R><A><T><W><M><A><L><Y><H><N><I><S><G><V><G><L><F><L><H><P><V><G><L><E><L><L><L><D><H><R><A><L><D><P><A><H><W><T><V><Q><Q><V><F><Y><L><G><H><Y><Y><A><D><L><G><Q><L><E><R><E><F><K><S><G><R><L><E><V><V><R><V><P><L><P><P><P><N><G><A><S><S><L><R><S><R><N><S><P><G><P><L><P><P><L><Q><F><S><P><Q><G><S><Q><Y><S><V><Q><G><N><L><V><V><S><S><L><W><S><F><T><F><G><H><G><V><F><S><G><L><R><I><F><D><V><R><F><Q><G><E><R><I><A><Y><E><V><S><V><Q><E><C><V><S><I><Y><G><A><D><S><P><K><T><M><L><T><R><Y><L><D><S><S><F><G><L><G><R><N><S><R><G><L><V><R><G><V><D><C><P><Y><Q><A><T><M><V><D><I><H><I><L><V><G><K><G><A><V><Q><L><L><P><G><A><V><C><V><F><E><E><A><Q><G><L><P><L><R><R><H><H><N><Y><L><Q><N><H><F><Y><G><G><L><A><S><S><A><L><V><V><R><S><V><S><S><V><G><N><Y><D><Y><I><W><D><F><V><L><Y><P><N><G><A><L><E><G><R><V><H><A><T><G><Y><I><N><T><A><F><L><K><G><G><E><E><G><L><L><F><G><N><R><V><G><E><R><V><L><G><T><V><H><T><H><A><F><H><F><K><L><D><L><D><V><A><G><L><K><N><W><V><V><A><E><D><V><V><F><K><P><V><A><A><P><W><N><P><E><H><W><L><Q><R><P><Q><L><T><R><Q><V><L><G><K><E><D><L><T><A><F><S><L><G><S><P><L><P><R><Y><L><Y><L><A><S><N><Q><T><N><A><W><G><H><Q><R><G><Y><R><I><Q><I><H><S><P><L><G><I><H><I><P><L><E><S><D><M><E><R><A><L><S><W><G><R><Y><Q><L><V><V><T><Q><R><K><E><E><E><S><Q><S><S><S><I><Y><H><Q><N><D><I><W><T><P><T><V><T><F><A><D><F><I><N><N><E><T><L><L><G><E><D><L><V><A><W><V><T><A><S><F><L><H><I><P><H><A><E><D><I><P><N><T><V><T><L><G><N><R><V><G><F><L><L><R><P><Y><N><F><F><D><E><D><P><S><I><F><S><P><G><S><V><Y><F><E><K><G><Q><D><A><G><L><C><S><I><N><P><V><A><C><L><P><D><L><A><A><C><V><P><D><L><P><P><F><S><Y><H><G><F>
Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.<BOP>
O75106
Q14919
NC2A_HUMAN
Negative cofactor 2-alpha
Homo
<M><P><S><K><K><K><K><Y><N><A><R><F><P><P><A><R><I><K><K><I><M><Q><T><D><E><E><I><G><K><V><A><A><A><V><P><V><I><I><S><R><A><L><E><L><F><L><E><S><L><L><K><K><A><C><Q><V><T><Q><S><R><N><A><K><T><M><T><T><S><H><L><K><Q><C><I><E><L><E><Q><Q><F><D><F><L><K><D><L><V><A><S><V><P><D><M><Q><G><D><G><E><D><N><H><M><D><G><D><K><G><A><R><R><G><R><K><P><G><S><G><G><R><K><N><G><G><M><G><T><K><S><K><D><K><K><L><S><G><T><D><S><E><Q><E><D><E><S><E><D><T><D><T><D><G><E><E><E><T><S><Q><P><P><P><Q><A><S><H><P><S><A><H><F><Q><S><P><P><T><P><F><L><P><F><A><S><T><L><P><L><P><P><A><P><P><G><P><S><A><P><D><E><E><D><E><E><D><Y><D><S>
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.<BOP>
Q14919
Q8IVA1
PCP2_HUMAN
Purkinje cell protein 2 homolog
Homo
<M><M><D><Q><E><E><K><T><E><E><G><S><G><P><C><A><E><A><G><S><P><D><Q><E><G><F><F><N><L><L><S><H><V><Q><G><D><R><M><E><G><Q><R><C><S><L><Q><A><G><P><G><Q><T><T><K><S><Q><S><D><P><T><P><E><M><D><S><L><M><D><M><L><A><S><T><Q><G><R><R><M><D><D><Q><R><V><T><V><S><S><L><P><G><F><Q><P><V><G><S><K><D><G><A><Q><K><R><A><G><T><L><S><P><Q><P><L><L><T><P><Q><D><P><T><A><L><G><F><R><R><N><S><S><P><Q><P><P><T><Q><A><P>
May function as a cell-type specific modulator for G protein-mediated cell signaling.<BOP>
Q8IVA1
Q9NUU6
OTULL_HUMAN
Inactive ubiquitin thioesterase OTULINL
Homo
<M><A><A><T><R><S><P><T><R><A><R><E><R><E><R><S><G><A><P><A><A><G><S><D><Q><V><H><S><W><M><L><A><T><S><Q><A><L><D><T><V><W><R><M><A><K><G><F><V><M><L><A><V><S><F><L><V><A><A><I><C><Y><F><R><R><L><H><L><Y><S><G><H><K><L><K><W><W><I><G><Y><L><Q><R><K><F><K><R><N><L><S><V><E><A><E><V><D><L><L><S><Y><C><A><R><E><W><K><G><E><T><P><R><N><K><L><M><R><K><A><Y><E><E><L><F><W><R><H><H><I><K><C><V><R><Q><V><R><R><D><N><Y><D><A><L><R><S><V><L><F><Q><I><F><S><Q><G><I><S><F><P><S><W><M><K><E><K><D><I><V><K><L><P><E><K><L><L><F><S><Q><G><C><N><W><I><Q><Q><Y><S><F><G><P><E><K><Y><T><G><S><N><V><F><G><K><L><R><K><Y><V><E><L><L><K><T><Q><W><T><E><F><N><G><I><R><D><Y><H><K><R><G><S><M><C><N><T><L><F><S><D><A><I><L><E><Y><K><L><Y><E><A><L><K><F><I><M><L><Y><Q><V><T><E><V><Y><E><Q><M><K><T><K><K><V><I><P><S><L><F><R><L><L><F><S><R><E><T><S><S><D><P><L><S><F><M><M><N><H><L><N><S><V><G><D><T><C><G><L><E><Q><I><D><M><F><I><L><G><Y><S><L><E><V><K><I><K><V><F><R><L><F><K><F><N><S><R><D><F><E><V><C><Y><P><E><E><P><L><R><D><W><P><E><I><S><L><L><T><E><N><D><R><H><Y><H><I><P><V><F>
Lacks deubiquitinase activity.<BOP>
Q9NUU6
Q494X3
ZN404_HUMAN
Zinc finger protein 404
Homo
<M><A><R><V><P><L><T><F><S><D><V><A><I><D><F><S><Q><E><E><W><E><Y><L><N><S><D><Q><R><D><L><Y><R><D><V><M><L><E><N><Y><T><N><L><V><S><L><D><F><N><F><T><T><E><S><N><K><L><S><S><E><K><R><N><Y><E><V><N><A><Y><H><Q><E><T><W><K><R><N><K><T><F><N><L><M><R><F><I><F><R><T><D><P><Q><Y><T><I><E><F><G><R><Q><Q><R><P><K><V><G><C><F><S><Q><M><I><F><K><K><H><K><S><L><P><L><H><K><R><N><N><T><R><E><K><S><Y><E><C><K><E><Y><K><K><G><F><R><K><Y><L><H><L><T><E><H><L><R><D><H><T><G><V><I><P><Y><E><C><N><E><C><G><K><A><F><V><V><F><Q><H><F><I><R><H><R><K><I><H><T><D><L><K><P><Y><E><C><N><G><C><E><K><A><F><R><F><Y><S><Q><L><I><Q><H><Q><I><I><H><T><G><M><K><P><Y><E><C><K><Q><C><G><K><A><F><R><R><H><S><H><L><T><E><H><Q><K><I><H><V><G><L><K><P><F><E><C><K><E><C><G><E><T><F><R><L><Y><R><H><M><C><L><H><Q><K><I><H><H><G><V><K><P><Y><K><C><K><E><C><G><K><A><F><G><H><R><S><S><L><Y><Q><H><K><K><I><H><S><G><E><K><P><Y><K><C><E><Q><C><E><K><A><F><V><R><S><Y><L><L><V><E><H><Q><R><S><H><T><G><E><K><P><H><E><C><M><E><C><G><K><A><F><G><K><G><S><S><L><L><K><H><K><R><I><H><S><S><E><K><L><Y><D><C><K><D><C><G><K><A><F><C><R><G><S><Q><L><T><Q><H><Q><R><I><H><T><G><E><K><P><H><E><C><K><E><C><G><K><T><F><K><L><H><S><Y><L><I><Q><H><Q><I><I><H><T><D><L><K><P><Y><E><C><K><Q><C><G><K><A><F><S><R><V><G><D><L><K><T><H><Q><S><I><H><A><G><E><K><P><Y><E><C><K><E><C><G><K><T><F><R><L><N><S><Q><L><I><Y><H><Q><T><I><H><T><G><L><K><P><Y><V><C><K><E><C><K><K><A><F><R><S><I><S><G><L><S><Q><H><K><R><I><H><T><G><E><K><P><Y><E><C><K><E><C><D><K><A><F><N><R><S><D><R><L><T><Q><H><E><T><I><H><T><G><V><K><P><Q><K><C><K><E><C><G><K><A><F><S><H><C><Y><Q><L><S><Q><H><Q><R><F><H><H><G><E><R><L><L><M>
May be involved in transcriptional regulation.<BOP>
Q494X3
P11230
ACHB_HUMAN
Acetylcholine receptor subunit beta
Homo
<M><T><P><G><A><L><L><M><L><L><G><A><L><G><A><P><L><A><P><G><V><R><G><S><E><A><E><G><R><L><R><E><K><L><F><S><G><Y><D><S><S><V><R><P><A><R><E><V><G><D><R><V><R><V><S><V><G><L><I><L><A><Q><L><I><S><L><N><E><K><D><E><E><M><S><T><K><V><Y><L><D><L><E><W><T><D><Y><R><L><S><W><D><P><A><E><H><D><G><I><D><S><L><R><I><T><A><E><S><V><W><L><P><D><V><V><L><L><N><N><N><D><G><N><F><D><V><A><L><D><I><S><V><V><V><S><S><D><G><S><V><R><W><Q><P><P><G><I><Y><R><S><S><C><S><I><Q><V><T><Y><F><P><F><D><W><Q><N><C><T><M><V><F><S><S><Y><S><Y><D><S><S><E><V><S><L><Q><T><G><L><G><P><D><G><Q><G><H><Q><E><I><H><I><H><E><G><T><F><I><E><N><G><Q><W><E><I><I><H><K><P><S><R><L><I><Q><P><P><G><D><P><R><G><G><R><E><G><Q><R><Q><E><V><I><F><Y><L><I><I><R><R><K><P><L><F><Y><L><V><N><V><I><A><P><C><I><L><I><T><L><L><A><I><F><V><F><Y><L><P><P><D><A><G><E><K><M><G><L><S><I><F><A><L><L><T><L><T><V><F><L><L><L><L><A><D><K><V><P><E><T><S><L><S><V><P><I><I><I><K><Y><L><M><F><T><M><V><L><V><T><F><S><V><I><L><S><V><V><V><L><N><L><H><H><R><S><P><H><T><H><Q><M><P><L><W><V><R><Q><I><F><I><H><K><L><P><L><Y><L><R><L><K><R><P><K><P><E><R><D><L><M><P><E><P><P><H><C><S><S><P><G><S><G><W><G><R><G><T><D><E><Y><F><I><R><K><P><P><S><D><F><L><F><P><K><P><N><R><F><Q><P><E><L><S><A><P><D><L><R><R><F><I><D><G><P><N><R><A><V><A><L><L><P><E><L><R><E><V><V><S><S><I><S><Y><I><A><R><Q><L><Q><E><Q><E><D><H><D><A><L><K><E><D><W><Q><F><V><A><M><V><V><D><R><L><F><L><W><T><F><I><I><F><T><S><V><G><T><L><V><I><F><L><D><A><T><Y><H><L><P><P><P><D><P><F><P>
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.<BOP>
P11230
Q8N3F9
G137C_HUMAN
Transmembrane 7 superfamily member 1-like 2 protein
Homo
<M><R><V><S><V><P><G><P><A><A><A><A><A><P><A><A><G><R><E><P><S><T><P><G><G><G><S><G><G><G><G><A><V><A><A><A><S><G><A><A><V><P><G><S><V><Q><L><A><L><S><V><L><H><A><L><L><Y><A><A><L><F><A><F><A><Y><L><Q><L><W><R><L><L><L><Y><R><E><R><R><L><S><Y><Q><S><L><C><L><F><L><C><L><L><W><A><A><L><R><T><T><L><F><S><A><A><F><S><L><S><G><S><L><P><L><L><R><P><P><A><H><L><H><F><F><P><H><W><L><L><Y><C><F><P><S><C><L><Q><F><S><T><L><C><L><L><N><L><Y><L><A><E><V><I><C><K><V><R><C><A><T><E><L><D><R><H><K><I><L><L><H><L><G><F><I><M><A><S><L><L><F><L><V><V><N><L><T><C><A><M><L><V><H><G><D><V><P><E><N><Q><L><K><W><T><V><F><V><R><A><L><I><N><D><S><L><F><I><L><C><A><I><S><L><V><C><Y><I><C><K><I><T><K><M><S><S><A><N><V><Y><L><E><S><K><G><M><S><L><C><Q><T><V><V><V><G><S><V><V><I><L><L><Y><S><S><R><A><C><Y><N><L><V><V><V><T><I><S><Q><D><T><L><E><S><P><F><N><Y><G><W><D><N><L><S><D><K><A><H><V><E><D><I><S><G><E><E><Y><I><V><F><G><M><V><L><F><L><W><E><H><V><P><A><W><S><V><V><L><F><F><R><A><Q><R><L><N><Q><N><L><A><P><A><G><M><I><N><S><H><S><Y><S><S><R><A><Y><F><F><D><N><P><R><R><Y><D><S><D><D><D><L><P><R><L><G><S><S><R><E><G><S><L><P><N><S><Q><S><L><G><W><Y><G><T><M><T><G><C><G><S><S><S><Y><T><V><T><P><H><L><N><G><P><M><T><D><T><A><P><L><L><F><T><C><S><N><L><D><L><N><N><H><H><S><L><Y><V><T><P><Q><N>
Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes.<BOP>
Q8N3F9
Q9P0N5
TM216_HUMAN
Transmembrane protein 216
Homo
<M><L><P><R><G><L><K><M><A><P><R><G><K><R><L><S><S><T><P><L><E><I><L><F><F><L><N><G><W><Y><N><A><T><Y><F><L><L><E><L><F><I><F><L><Y><K><G><V><L><L><P><Y><P><T><A><N><L><V><L><D><V><V><M><L><L><L><Y><L><G><I><E><V><I><R><L><F><F><G><T><K><G><N><L><C><Q><R><K><M><P><L><S><I><S><V><A><L><T><F><P><S><A><M><M><A><S><Y><Y><L><L><L><Q><T><Y><V><L><R><L><E><A><I><M><N><G><I><L><L><F><F><C><G><S><E><L><L><L><E><V><L><T><L><A><A><F><S><R><I>
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.<BOP>
Q9P0N5
Q9BRT9
SLD5_HUMAN
DNA replication complex GINS protein SLD5, N-terminally processed
Homo
<M><T><E><E><V><D><F><L><G><Q><D><S><D><G><G><S><E><E><V><V><L><T><P><A><E><L><I><E><R><L><E><Q><A><W><M><N><E><K><F><A><P><E><L><L><E><S><K><P><E><I><V><E><C><V><M><E><Q><L><E><H><M><E><E><N><L><R><R><A><K><R><E><D><L><K><V><S><I><H><Q><M><E><M><E><R><I><R><Y><V><L><S><S><Y><L><R><C><R><L><M><K><I><E><K><F><F><P><H><V><L><E><K><E><K><T><R><P><E><G><E><P><S><S><L><S><P><E><E><L><A><F><A><R><E><F><M><A><N><T><E><S><Y><L><K><N><V><A><L><K><H><M><P><P><N><L><Q><K><V><D><L><F><R><A><V><P><K><P><D><L><D><S><Y><V><F><L><R><V><R><E><R><Q><E><N><I><L><V><E><P><D><T><D><E><Q><R><D><Y><V><I><D><L><E><K><G><S><Q><H><L><I><R><Y><K><T><I><A><P><L><V><A><S><G><A><V><Q><L><I>
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks . GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built .<BOP>
Q9BRT9
Q9H6Q4
CIAO3_HUMAN
Protein related to Narf
Homo
<M><A><S><P><F><S><G><A><L><Q><L><T><D><L><D><D><F><I><G><P><S><Q><E><C><I><K><P><V><K><V><E><K><R><A><G><S><G><V><A><K><I><R><I><E><D><D><G><S><Y><F><Q><I><N><Q><D><G><G><T><R><R><L><E><K><A><K><V><S><L><N><D><C><L><A><C><S><G><C><I><T><S><A><E><T><V><L><I><T><Q><Q><S><H><E><E><L><K><K><V><L><D><A><N><K><M><A><A><P><S><Q><Q><R><L><V><V><V><S><V><S><P><Q><S><R><A><S><L><A><A><R><F><Q><L><N><P><T><D><T><A><R><K><L><T><S><F><F><K><K><I><G><V><H><F><V><F><D><T><A><F><S><R><H><F><S><L><L><E><S><Q><R><E><F><V><R><R><F><R><G><Q><A><D><C><R><Q><A><L><P><L><L><A><S><A><C><P><G><W><I><C><Y><A><E><K><T><H><G><S><F><I><L><P><H><I><S><T><A><R><S><P><Q><Q><V><M><G><S><L><V><K><D><F><F><A><Q><Q><Q><H><L><T><P><D><K><I><Y><H><V><T><V><M><P><C><Y><D><K><K><L><E><A><S><R><P><D><F><F><N><Q><E><H><Q><T><R><D><V><D><C><V><L><T><T><G><E><V><F><R><L><L><E><E><E><G><V><S><L><P><D><L><E><P><A><P><L><D><S><L><C><S><G><A><S><A><E><E><P><T><S><H><R><G><G><G><S><G><G><Y><L><E><H><V><F><R><H><A><A><R><E><L><F><G><I><H><V><A><E><V><T><Y><K><P><L><R><N><K><D><F><Q><E><V><T><L><E><K><E><G><Q><V><L><L><H><F><A><M><A><Y><G><F><R><N><I><Q><N><L><V><Q><R><L><K><R><G><R><C><P><Y><H><Y><V><E><V><M><A><C><P><S><G><C><L><N><G><G><G><Q><L><Q><A><P><D><R><P><S><R><E><L><L><Q><H><V><E><R><L><Y><G><M><V><R><A><E><A><P><E><D><A><P><G><V><Q><E><L><Y><T><H><W><L><Q><G><T><D><S><E><C><A><G><R><L><L><H><T><Q><Y><H><A><V><E><K><A><S><T><G><L><G><I><R><W>
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.<BOP>
Q9H6Q4
Q96A04
TSACC_HUMAN
SSTK-interacting protein
Homo
<M><E><R><H><T><S><H><P><N><R><K><V><P><A><K><E><E><A><N><A><V><P><L><C><R><A><K><P><S><P><S><Y><I><N><L><Q><A><S><S><P><P><A><T><F><L><N><I><Q><T><T><K><L><P><S><V><D><H><K><P><K><E><C><L><G><L><L><E><C><M><Y><A><N><L><Q><L><Q><T><Q><L><A><Q><Q><Q><M><A><V><L><E><H><L><Q><A><S><V><T><Q><L><A><P><G><R><G><S><N><N><S><S><L><P><A><L><S><P><N><P><L><L><N><H><L><P><Q><F><S><K>
Co-chaperone that facilitates HSP-mediated activation of TSSK6.<BOP>
Q96A04
Q9UBQ0
VPS29_HUMAN
Vesicle protein sorting 29
Homo
<M><L><V><L><V><L><G><D><L><H><I><P><H><R><C><N><S><L><P><A><K><F><K><K><L><L><V><P><G><K><I><Q><H><I><L><C><T><G><N><L><C><T><K><E><S><Y><D><Y><L><K><T><L><A><G><D><V><H><I><V><R><G><D><F><D><E><N><L><N><Y><P><E><Q><K><V><V><T><V><G><Q><F><K><I><G><L><I><H><G><H><Q><V><I><P><W><G><D><M><A><S><L><A><L><L><Q><R><Q><F><D><V><D><I><L><I><S><G><H><T><H><K><F><E><A><F><E><H><E><N><K><F><Y><I><N><P><G><S><A><T><G><A><Y><N><A><L><E><T><N><I><I><P><S><F><V><L><M><D><I><Q><A><S><T><V><V><T><Y><V><Y><Q><L><I><G><D><D><V><K><V><E><R><I><E><Y><K><K><P>
(Microbial infection) The heterotrimeric retromer cargo-selective complex (CSC) mediates the exit of human papillomavirus from the early endosome and the delivery to the Golgi apparatus.<BOP>
Q9UBQ0
Q8IUF1
ZNG1B_HUMAN
Cobalamin synthase W domain-containing protein 2
Homo
<M><L><P><A><V><G><S><A><D><E><E><E><D><P><A><E><E><D><C><P><E><L><V><P><M><E><T><T><Q><S><E><E><E><E><K><S><G><L><G><A><K><I><P><V><T><I><I><T><G><Y><L><G><A><G><K><T><T><L><L><N><Y><I><L><T><E><Q><H><S><K><R><V><A><V><I><L><N><E><F><G><E><G><S><A><L><E><K><S><L><A><V><S><Q><G><G><E><L><Y><E><E><W><L><E><L><R><N><G><C><L><C><C><S><V><K><D><N><G><L><R><A><I><E><N><L><M><Q><K><K><G><K><F><D><Y><I><L><L><E><T><T><G><L><A><D><P><G><A><V><A><S><M><F><W><V><D><A><E><L><G><S><D><I><Y><L><D><G><I><I><T><I><V><D><S><K><Y><G><L><K><H><L><A><E><E><K><P><D><G><L><I><N><E><A><T><R><Q><V><A><L><A><D><A><I><L><I><N><K><T><D><L><V><P><E><E><D><V><K><K><L><R><A><T><I><R><S><I><N><G><L><G><Q><I><L><E><T><Q><R><S><R><V><D><L><S><N><V><L><D><L><H><A><F><D><S><L><S><G><I><S><L><Q><K><K><L><Q><H><V><P><G><T><Q><P><H><L><D><Q><S><I><V><T><I><T><F><E><V><P><G><N><A><K><E><E><H><L><N><M><F><I><Q><N><L><L><W><E><K><N><V><R><N><K><D><N><H><C><M><E><V><I><R><L><K><G><L><V><S><I><K><D><K><S><Q><Q><V><I><V><Q><G><V><H><E><L><Y><D><L><E><E><T><P><V><S><W><K><D><D><T><E><R><T><N><R><L><V><L><L><G><R><N><L><D><K><D><I><L><K><Q><L><F><I><A><T><V><T><E><T><E><K><Q><W><T><T><H><F><K><E><D><Q><V><C><T>
Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1B to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1.<BOP>
Q8IUF1
P56962
STX17_HUMAN
Syntaxin-17
Homo
<M><S><E><D><E><E><K><V><K><L><R><R><L><E><P><A><I><Q><K><F><I><K><I><V><I><P><T><D><L><E><R><L><R><K><H><Q><I><N><I><E><K><Y><Q><R><C><R><I><W><D><K><L><H><E><E><H><I><N><A><G><R><T><V><Q><Q><L><R><S><N><I><R><E><I><E><K><L><C><L><K><V><R><K><D><D><L><V><L><L><K><R><M><I><D><P><V><K><E><E><A><S><A><A><T><A><E><F><L><Q><L><H><L><E><S><V><E><E><L><K><K><Q><F><N><D><E><E><T><L><L><Q><P><P><L><T><R><S><M><T><V><G><G><A><F><H><T><T><E><A><E><A><S><S><Q><S><L><T><Q><I><Y><A><L><P><E><I><P><Q><D><Q><N><A><A><E><S><W><E><T><L><E><A><D><L><I><E><L><S><Q><L><V><T><D><F><S><L><L><V><N><S><Q><Q><E><K><I><D><S><I><A><D><H><V><N><S><A><A><V><N><V><E><E><G><T><K><N><L><G><K><A><A><K><Y><K><L><A><A><L><P><V><A><G><A><L><I><G><G><M><V><G><G><P><I><G><L><L><A><G><F><K><V><A><G><I><A><A><A><L><G><G><G><V><L><G><F><T><G><G><K><L><I><Q><R><K><K><Q><K><M><M><E><K><L><T><S><S><C><P><D><L><P><S><Q><T><D><K><K><C><S>
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion . STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane . May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi .<BOP>
P56962
P43155
CACP_HUMAN
Carnitine acetyltransferase
Homo
<M><L><A><F><A><A><R><T><V><V><K><P><L><G><F><L><K><P><F><S><L><M><K><A><S><S><R><F><K><A><H><Q><D><A><L><P><R><L><P><V><P><P><L><Q><Q><S><L><D><H><Y><L><K><A><L><Q><P><I><V><S><E><E><E><W><A><H><T><K><Q><L><V><D><E><F><Q><A><S><G><G><V><G><E><R><L><Q><K><G><L><E><R><R><A><R><K><T><E><N><W><L><S><E><W><W><L><K><T><A><Y><L><Q><Y><R><Q><P><V><V><I><Y><S><S><P><G><V><M><L><P><K><Q><D><F><V><D><L><Q><G><Q><L><R><F><A><A><K><L><I><E><G><V><L><D><F><K><V><M><I><D><N><E><T><L><P><V><E><Y><L><G><G><K><P><L><C><M><N><Q><Y><Y><Q><I><L><S><S><C><R><V><P><G><P><K><Q><D><T><V><S><N><F><S><K><T><K><K><P><P><T><H><I><T><V><V><H><N><Y><Q><F><F><E><L><D><V><Y><H><S><D><G><T><P><L><T><A><D><Q><I><F><V><Q><L><E><K><I><W><N><S><S><L><Q><T><N><K><E><P><V><G><I><L><T><S><N><H><R><N><S><W><A><K><A><Y><N><T><L><I><K><D><K><V><N><R><D><S><V><R><S><I><Q><K><S><I><F><T><V><C><L><D><A><T><M><P><R><V><S><E><D><V><Y><R><S><H><V><A><G><Q><M><L><H><G><G><G><S><R><L><N><S><G><N><R><W><F><D><K><T><L><Q><F><I><V><A><E><D><G><S><C><G><L><V><Y><E><H><A><A><A><E><G><P><P><I><V><T><L><L><D><Y><V><I><E><Y><T><K><K><P><E><L><V><R><S><P><L><V><P><L><P><M><P><K><K><L><R><F><N><I><T><P><E><I><K><S><D><I><E><K><A><K><Q><N><L><S><I><M><I><Q><D><L><D><I><T><V><M><V><F><H><H><F><G><K><D><F><P><K><S><E><K><L><S><P><D><A><F><I><Q><M><A><L><Q><L><A><Y><Y><R><I><Y><G><Q><A><C><A><T><Y><E><S><A><S><L><R><M><F><H><L><G><R><T><D><T><I><R><S><A><S><M><D><S><L><T><F><V><K><A><M><D><D><S><S><V><T><E><H><Q><K><V><E><L><L><R><K><A><V><Q><A><H><R><G><Y><T><D><R><A><I><R><G><E><A><F><D><R><H><L><L><G><L><K><L><Q><A><I><E><D><L><V><S><M><P><D><I><F><M><D><T><S><Y><A><I><A><M><H><F><H><L><S><T><S><Q><V><P><A><K><T><D><C><V><M><F><F><G><P><V><V><P><D><G><Y><G><V><C><Y><N><P><M><E><A><H><I><N><F><S><L><S><A><Y><N><S><C><A><E><T><N><A><A><R><L><A><H><Y><L><E><K><A><L><L><D><M><R><A><L><L><Q><S><H><P><R><A><K><L>
Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation . Responsible for the synthesis of short- and branched-chain acylcarnitines . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates . Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates .<BOP>
P43155
O75190
DNJB6_HUMAN
MSJ-1
Homo
<M><V><D><Y><Y><E><V><L><G><V><Q><R><H><A><S><P><E><D><I><K><K><A><Y><R><K><L><A><L><K><W><H><P><D><K><N><P><E><N><K><E><E><A><E><R><K><F><K><Q><V><A><E><A><Y><E><V><L><S><D><A><K><K><R><D><I><Y><D><K><Y><G><K><E><G><L><N><G><G><G><G><G><G><S><H><F><D><S><P><F><E><F><G><F><T><F><R><N><P><D><D><V><F><R><E><F><F><G><G><R><D><P><F><S><F><D><F><F><E><D><P><F><E><D><F><F><G><N><R><R><G><P><R><G><S><R><S><R><G><T><G><S><F><F><S><A><F><S><G><F><P><S><F><G><S><G><F><S><S><F><D><T><G><F><T><S><F><G><S><L><G><H><G><G><L><T><S><F><S><S><T><S><F><G><G><S><G><M><G><N><F><K><S><I><S><T><S><T><K><M><V><N><G><R><K><I><T><T><K><R><I><V><E><N><G><Q><E><R><V><E><V><E><E><D><G><Q><L><K><S><L><T><I><N><G><V><A><D><D><D><A><L><A><E><E><R><M><R><R><G><Q><N><A><L><P><A><Q><P><A><G><L><R><P><P><K><P><P><R><P><A><S><L><L><R><H><A><P><H><C><L><S><E><E><E><G><E><Q><D><R><P><R><A><P><G><P><W><D><P><L><A><S><A><A><G><L><K><E><G><G><K><R><K><K><Q><K><Q><R><E><E><S><K><K><K><K><S><T><K><G><N><H>
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.<BOP>
O75190
Q8N628
OR2C3_HUMAN
Olfactory receptor OR1-30
Homo
<M><M><E><I><A><N><V><S><S><P><E><V><F><V><L><L><G><F><S><T><R><P><S><L><E><T><V><L><F><I><V><V><L><S><F><Y><M><V><S><I><L><G><N><G><I><I><I><L><V><S><H><T><D><V><H><L><H><T><P><M><Y><F><F><L><A><N><L><P><F><L><D><M><S><F><T><T><S><I><V><P><Q><L><L><A><N><L><W><G><P><Q><K><T><I><S><Y><G><G><C><V><V><Q><F><Y><I><S><H><W><L><G><A><T><E><C><V><L><L><A><T><M><S><Y><D><R><Y><A><A><I><C><R><P><L><H><Y><T><V><I><M><H><P><Q><L><C><L><G><L><A><L><A><S><W><L><G><G><L><T><T><S><M><V><G><S><T><L><T><M><L><L><P><L><C><G><N><N><C><I><D><H><F><F><C><E><M><P><L><I><M><Q><L><A><C><V><D><T><S><L><N><E><M><E><M><Y><L><A><S><F><V><F><V><V><L><P><L><G><L><I><L><V><S><Y><G><H><I><A><R><A><V><L><K><I><R><S><A><E><G><R><R><K><A><F><N><T><C><S><S><H><V><A><V><V><S><L><F><Y><G><S><I><I><F><M><Y><L><Q><P><A><K><S><T><S><H><E><Q><G><K><F><I><A><L><F><Y><T><V><V><T><P><A><L><N><P><L><I><Y><T><L><R><N><T><E><V><K><S><A><L><R><H><M><V><L><E><N><C><C><G><S><A><G><K><L><A><Q><I>
Odorant receptor.<BOP>
Q8N628
Q96T55
KCNKG_HUMAN
TWIK-related alkaline pH-activated K(+) channel 1
Homo
<M><P><S><A><G><L><C><S><C><W><G><G><R><V><L><P><L><L><L><A><Y><V><C><Y><L><L><L><G><A><T><I><F><Q><L><L><E><R><Q><A><E><A><Q><S><R><D><Q><F><Q><L><E><K><L><R><F><L><E><N><Y><T><C><L><D><Q><W><A><M><E><Q><F><V><Q><V><I><M><E><A><W><V><K><G><V><N><P><K><G><N><S><T><N><P><S><N><W><D><F><G><S><S><F><F><F><A><G><T><V><V><T><T><I><G><Y><G><N><L><A><P><S><T><E><A><G><Q><V><F><C><V><F><Y><A><L><L><G><I><P><L><N><V><I><F><L><N><H><L><G><T><G><L><R><A><H><L><A><A><I><E><R><W><E><D><R><P><R><R><S><Q><V><L><Q><V><L><G><L><A><L><F><L><T><L><G><T><L><V><I><L><I><F><P><P><M><V><F><S><H><V><E><G><W><S><F><S><E><G><F><Y><F><A><F><I><T><L><S><T><I><G><F><G><D><Y><V><V><G><T><D><P><S><K><H><Y><I><S><V><Y><R><S><L><A><A><I><W><I><L><L><G><L><A><W><L><A><L><I><L><P><L><G><P><L><L><L><H><R><C><C><Q><L><W><L><L><S><L><R><Q><G><C><G><A><K><A><A><P><G><R><R><P><R><R><G><S><T><A><A><R><G><V><Q><V><T><P><Q><D><F><P><I><S><K><K><G><L><G><S>
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.<BOP>
Q96T55
Q9GZT3
SLIRP_HUMAN
SRA stem-loop-interacting RNA-binding protein, mitochondrial
Homo
<M><A><A><S><A><A><R><G><A><A><A><L><R><R><S><I><N><Q><P><V><A><F><V><R><R><I><P><W><T><A><A><S><S><Q><L><K><E><H><F><A><Q><F><G><H><V><R><R><C><I><L><P><F><D><K><E><T><G><F><H><R><G><L><G><W><V><Q><F><S><S><E><E><G><L><R><N><A><L><Q><Q><E><N><H><I><I><D><G><V><K><V><Q><V><H><T><R><R><P><K><L><P><Q><T><S><D><D><E><K><K><D><F>
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.<BOP>
Q9GZT3
Q86YR5
GPSM1_HUMAN
Activator of G-protein signaling 3
Homo
<M><A><G><P><A><P><P><V><A><D><E><L><P><G><P><A><A><R><R><L><Y><S><R><M><E><A><S><C><L><E><L><A><L><E><G><E><R><L><C><K><A><G><D><F><K><T><G><V><A><F><F><E><A><A><V><Q><V><G><T><E><D><L><K><T><L><S><A><I><Y><S><Q><L><G><N><A><Y><F><Y><L><K><E><H><G><R><A><L><E><Y><H><K><H><D><L><L><L><A><R><T><I><G><D><R><M><G><E><A><K><A><S><G><N><L><G><N><T><L><K><V><L><G><R><F><D><E><A><A><V><C><C><Q><R><H><L><S><I><A><Q><E><Q><G><D><K><V><G><E><A><R><A><L><Y><N><I><G><N><V><Y><H><A><K><G><K><Q><L><S><W><N><A><A><N><A><T><Q><D><P><G><H><L><P><P><D><V><R><E><T><L><C><K><A><S><E><F><Y><E><R><N><L><S><L><V><K><E><L><G><D><R><A><A><Q><G><R><A><Y><G><N><L><G><N><T><H><Y><L><L><G><N><F><T><E><A><T><T><F><H><K><E><R><L><A><I><A><K><E><F><G><D><K><A><A><E><R><R><A><Y><S><N><L><G><N><A><H><V><F><L><G><R><F><D><V><A><A><E><Y><Y><K><K><T><L><Q><L><S><R><Q><L><R><D><Q><A><V><E><A><Q><A><C><Y><S><L><G><N><T><Y><T><L><L><Q><D><Y><E><R><A><A><E><Y><H><L><R><H><L><L><I><A><Q><E><L><A><D><R><V><G><E><G><R><A><C><W><S><L><G><N><A><Y><V><S><M><G><R><P><A><Q><A><L><T><F><A><K><K><H><L><Q><I><S><Q><E><I><G><D><R><H><G><E><L><T><A><R><M><N><V><A><Q><L><Q><L><V><L><G><R><L><T><S><P><A><A><S><E><K><P><D><L><A><G><Y><E><A><Q><G><A><R><P><K><R><T><Q><R><L><S><A><E><T><W><D><L><L><R><L><P><L><E><R><E><Q><N><G><D><S><H><H><S><G><D><W><R><G><P><S><R><D><S><L><P><L><P><V><R><S><R><K><Y><Q><E><G><P><D><A><E><R><R><P><R><E><G><S><H><S><P><L><D><S><A><D><V><R><V><H><V><P><R><T><S><I><P><R><A><P><S><S><D><E><E><C><F><F><D><L><L><T><K><F><Q><S><S><R><M><D><D><Q><R><C><P><L><D><D><G><Q><A><G><A><A><E><A><T><A><A><P><T><L><E><D><R><I><A><Q><P><S><M><T><A><S><P><Q><T><E><E><F><F><D><L><I><A><S><S><Q><S><R><R><L><D><D><Q><R><A><S><V><G><S><L><P><G><L><R><I><T><H><S><N><A><G><H><L><R><G><H><G><E><P><Q><E><P><G><D><D><F><F><N><M><L><I><K><Y><Q><S><S><R><I><D><D><Q><R><C><P><P><P><D><V><L><P><R><G><P><T><M><P><D><E><D><F><F><S><L><I><Q><R><V><Q><A><K><R><M><D><E><Q><R><V><D><L><A><G><G><P><E><Q><G><A><G><G><P><P><E><P><Q><Q><Q><C><Q><P><G><A><S>
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.<BOP>
Q86YR5
Q7Z7A4
PXK_HUMAN
Modulator of Na,K-ATPase
Homo
<M><A><F><M><E><K><P><P><A><G><K><V><L><L><D><D><T><V><P><L><T><A><A><I><E><A><S><Q><S><L><Q><S><H><T><E><Y><I><I><R><V><Q><R><G><I><S><V><E><N><S><W><Q><I><V><R><R><Y><S><D><F><D><L><L><N><N><S><L><Q><I><A><G><L><S><L><P><L><P><P><K><K><L><I><G><N><M><D><R><E><F><I><A><E><R><Q><K><G><L><Q><N><Y><L><N><V><I><T><T><N><H><I><L><S><N><C><E><L><V><K><K><F><L><D><P><N><N><Y><S><A><N><Y><T><E><I><A><L><Q><Q><V><S><M><F><F><R><S><E><P><K><W><E><V><V><E><P><L><K><D><I><G><W><R><I><R><K><K><Y><F><L><M><K><I><K><N><Q><P><K><E><R><L><V><L><S><W><A><D><L><G><P><D><K><Y><L><S><D><K><D><F><Q><C><L><I><K><L><L><P><S><C><L><H><P><Y><I><Y><R><V><T><F><A><T><A><N><E><S><S><A><L><L><I><R><M><F><N><E><K><G><T><L><K><D><L><I><Y><K><A><K><P><K><D><P><F><L><K><K><Y><C><N><P><K><K><I><Q><G><L><E><L><Q><Q><I><K><T><Y><G><R><Q><I><L><E><V><L><K><F><L><H><D><K><G><F><P><Y><G><H><L><H><A><S><N><V><M><L><D><G><D><T><C><R><L><L><D><L><E><N><S><L><L><G><L><P><S><F><Y><R><S><Y><F><S><Q><F><R><K><I><N><T><L><E><S><V><D><V><H><C><F><G><H><L><L><Y><E><M><T><Y><G><R><P><P><D><S><V><P><V><D><S><F><P><P><A><P><S><M><A><V><V><A><V><L><E><S><T><L><S><C><E><A><C><K><N><G><M><P><T><I><S><R><L><L><Q><M><P><L><F><S><D><V><L><L><T><T><S><E><K><P><Q><F><K><I><P><T><K><L><K><E><A><L><R><I><A><K><E><C><I><E><K><R><L><I><E><E><Q><K><Q><I><H><Q><H><R><R><L><T><R><A><Q><S><H><H><G><S><E><E><E><R><K><K><R><K><I><L><A><R><K><K><S><K><R><S><A><L><E><N><S><E><E><H><S><A><K><Y><S><N><S><N><N><S><A><G><S><G><A><S><S><P><L><T><S><P><S><S><P><T><P><P><S><T><S><G><I><S><A><L><P><P><P><P><P><P><P><P><P><P><A><A><P><L><P><P><A><S><T><E><A><P><A><Q><L><S><S><Q><A><V><N><G><M><S><R><G><A><L><L><S><S><I><Q><N><F><Q><K><G><T><L><R><K><A><K><T><C><D><H><S><A><P><K><I><G>
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.<BOP>
Q7Z7A4
P30279
CCND2_HUMAN
G1/S-specific cyclin-D2
Homo
<M><E><L><L><C><H><E><V><D><P><V><R><R><A><V><R><D><R><N><L><L><R><D><D><R><V><L><Q><N><L><L><T><I><E><E><R><Y><L><P><Q><C><S><Y><F><K><C><V><Q><K><D><I><Q><P><Y><M><R><R><M><V><A><T><W><M><L><E><V><C><E><E><Q><K><C><E><E><E><V><F><P><L><A><M><N><Y><L><D><R><F><L><A><G><V><P><T><P><K><S><H><L><Q><L><L><G><A><V><C><M><F><L><A><S><K><L><K><E><T><S><P><L><T><A><E><K><L><C><I><Y><T><D><N><S><I><K><P><Q><E><L><L><E><W><E><L><V><V><L><G><K><L><K><W><N><L><A><A><V><T><P><H><D><F><I><E><H><I><L><R><K><L><P><Q><Q><R><E><K><L><S><L><I><R><K><H><A><Q><T><F><I><A><L><C><A><T><D><F><K><F><A><M><Y><P><P><S><M><I><A><T><G><S><V><G><A><A><I><C><G><L><Q><Q><D><E><E><V><S><S><L><T><C><D><A><L><T><E><L><L><A><K><I><T><N><T><D><V><D><C><L><K><A><C><Q><E><Q><I><E><A><V><L><L><N><S><L><Q><Q><Y><R><Q><D><Q><R><D><G><S><K><S><E><D><E><L><D><Q><A><S><T><P><T><D><V><R><D><I><D><L>
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition . Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase . Hypophosphorylates RB1 in early G(1) phase . Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals .<BOP>
P30279
Q9NS23
RASF1_HUMAN
Ras association domain-containing protein 1
Homo
<M><S><G><E><P><E><L><I><E><L><R><E><L><A><P><A><G><R><A><G><K><G><R><T><R><L><E><R><A><N><A><L><R><I><A><R><G><T><A><C><N><P><T><R><Q><L><V><P><G><R><G><H><R><F><Q><P><A><G><P><A><T><H><T><W><C><D><L><C><G><D><F><I><W><G><V><V><R><K><G><L><Q><C><A><R><L><S><A><D><C><K><F><T><C><H><Y><R><C><R><A><L><V><C><L><D><C><C><G><P><R><D><L><G><W><E><P><A><V><E><R><D><T><N><V><D><E><P><V><E><W><E><T><P><D><L><S><Q><A><E><I><E><Q><K><I><K><E><Y><N><A><Q><I><N><S><N><L><F><M><S><L><N><K><D><G><S><Y><T><G><F><I><K><V><Q><L><K><L><V><R><P><V><S><V><P><S><S><K><K><P><P><S><L><Q><D><A><R><R><G><P><G><R><G><T><S><V><R><R><R><T><S><F><Y><L><P><K><D><A><V><K><H><L><H><V><L><S><R><T><R><A><R><E><V><I><E><A><L><L><R><K><F><L><V><V><D><D><P><R><K><F><A><L><F><E><R><A><E><R><H><G><Q><V><Y><L><R><K><L><L><D><D><E><Q><P><L><R><L><R><L><L><A><G><P><S><D><K><A><L><S><F><V><L><K><E><N><D><S><G><E><V><N><W><D><A><F><S><M><P><E><L><H><N><F><L><R><I><L><Q><R><E><E><E><E><H><L><R><Q><I><L><Q><K><Y><S><Y><C><R><Q><K><I><Q><E><A><L><H><A><C><P><L><G>
Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.<BOP>
Q9NS23
Q8N461
FXL16_HUMAN
F-box and leucine-rich repeat protein 16
Homo
<M><S><S><P><G><I><D><G><D><P><K><P><P><C><L><P><R><N><G><L><V><K><L><P><G><Q><P><N><G><L><G><A><A><S><I><T><K><G><T><P><A><T><K><N><R><P><C><Q><P><P><P><P><P><T><L><P><P><P><S><L><A><A><P><L><S><R><A><A><L><A><G><G><P><C><T><P><A><G><G><P><A><S><A><L><A><P><G><H><P><A><E><R><P><P><L><A><T><D><E><K><I><L><N><G><L><F><W><Y><F><S><A><C><E><K><C><V><L><A><Q><V><C><K><A><W><R><R><V><L><Y><Q><P><K><F><W><A><G><L><T><P><V><L><H><A><K><E><L><Y><N><V><L><P><G><G><E><K><E><F><V><N><L><Q><G><F><A><A><R><G><F><E><G><F><C><L><V><G><V><S><D><L><D><I><C><E><F><I><D><N><Y><A><L><S><K><K><G><V><K><A><M><S><L><K><R><S><T><I><T><D><A><G><L><E><V><M><L><E><Q><M><Q><G><V><V><R><L><E><L><S><G><C><N><D><F><T><E><A><G><L><W><S><S><L><S><A><R><I><T><S><L><S><V><S><D><C><I><N><V><A><D><D><A><I><A><A><I><S><Q><L><L><P><N><L><A><E><L><S><L><Q><A><Y><H><V><T><D><T><A><L><A><Y><F><T><A><R><Q><G><H><S><T><H><T><L><R><L><L><S><C><W><E><I><T><N><H><G><V><V><N><V><V><H><S><L><P><N><L><T><A><L><S><L><S><G><C><S><K><V><T><D><D><G><V><E><L><V><A><E><N><L><R><K><L><R><S><L><D><L><S><W><C><P><R><I><T><D><M><A><L><E><Y><V><A><C><D><L><H><R><L><E><E><L><V><L><D><R><C><V><R><I><T><D><T><G><L><S><Y><L><S><T><M><S><S><L><R><S><L><Y><L><R><W><C><C><Q><V><Q><D><F><G><L><K><H><L><L><A><L><G><S><L><R><L><L><S><L><A><G><C><P><L><L><T><T><T><G><L><S><G><L><V><Q><L><Q><E><L><E><E><L><E><L><T><N><C><P><G><A><T><P><E><L><F><K><Y><F><S><Q><H><L><P><R><C><L><V><I><E>
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<BOP>
Q8N461
Q9UMR7
CLC4A_HUMAN
Lectin-like immunoreceptor
Homo
<M><T><S><E><I><T><Y><A><E><V><R><F><K><N><E><F><K><S><S><G><I><N><T><A><S><S><A><A><S><K><E><R><T><A><P><H><K><S><N><T><G><F><P><K><L><L><C><A><S><L><L><I><F><F><L><L><L><A><I><S><F><F><I><A><F><V><I><F><F><Q><K><Y><S><Q><L><L><E><K><K><T><T><K><E><L><V><H><T><T><L><E><C><V><K><K><N><M><P><V><E><E><T><A><W><S><C><C><P><K><N><W><K><S><F><S><S><N><C><Y><F><I><S><T><E><S><A><S><W><Q><D><S><E><K><D><C><A><R><M><E><A><H><L><L><V><I><N><T><Q><E><E><Q><D><F><I><F><Q><N><L><Q><E><E><S><A><Y><F><V><G><L><S><D><P><E><G><Q><R><H><W><Q><W><V><D><Q><T><P><Y><N><E><S><S><T><F><W><H><P><R><E><P><S><D><P><N><E><R><C><V><V><L><N><F><R><K><S><P><K><R><W><G><W><N><D><V><N><C><L><G><P><Q><R><S><V><C><E><M><M><K><I><H><L>
(Microbial infection) Involved in the interaction between HIV-1 virus and dendritic cells. Enhances HIV-1 binding/entry and virus infection. Requires ITIM motif-associated signal transduction pathway involving phosphatases PTPN6 and PTPN11, SYK, Src kinases and MAP kinases.<BOP>
Q9UMR7
Q7L1Q6
5MP2_HUMAN
Protein Orf
Homo
<M><N><N><Q><K><Q><Q><K><P><T><L><S><G><Q><R><F><K><T><R><K><R><D><E><K><E><R><F><D><P><T><Q><F><Q><D><C><I><I><Q><G><L><T><E><T><G><T><D><L><E><A><V><A><K><F><L><D><A><S><G><A><K><L><D><Y><R><R><Y><A><E><T><L><F><D><I><L><V><A><G><G><M><L><A><P><G><G><T><L><A><D><D><M><M><R><T><D><V><C><V><F><A><A><Q><E><D><L><E><T><M><Q><A><F><A><Q><V><F><N><K><L><I><R><R><Y><K><Y><L><E><K><G><F><E><D><E><V><K><K><L><L><L><F><L><K><G><F><S><E><S><E><R><N><K><L><A><M><L><T><G><V><L><L><A><N><G><T><L><N><A><S><I><L><N><S><L><Y><N><E><N><L><V><K><E><G><V><S><A><A><F><A><V><K><L><F><K><S><W><I><N><E><K><D><I><N><A><V><A><A><S><L><R><K><V><S><M><D><N><R><L><M><E><L><F><P><A><N><K><Q><S><V><E><H><F><T><K><Y><F><T><E><A><G><L><K><E><L><S><E><Y><V><R><N><Q><Q><T><I><G><A><R><K><E><L><Q><K><E><L><Q><E><Q><M><S><R><G><D><P><F><K><D><I><I><L><Y><V><K><E><E><M><K><K><N><N><I><P><E><P><V><V><I><G><I><V><W><S><S><V><M><S><T><V><E><W><N><K><K><E><E><L><V><A><E><Q><A><I><K><H><L><K><Q><Y><S><P><L><L><A><A><F><T><T><Q><G><Q><S><E><L><T><L><L><L><K><I><Q><E><Y><C><Y><D><N><I><H><F><M><K><A><F><Q><K><I><V><V><L><F><Y><K><A><E><V><L><S><E><E><P><I><L><K><W><Y><K><D><A><H><V><A><K><G><K><S><V><F><L><E><Q><M><K><K><F><V><E><W><L><K><N><A><E><E><E><S><E><S><E><A><E><E><G><D>
Translation initiation regulator which represses repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function . Enhances histone H4 gene transcription but does not seem to bind DNA directly .<BOP>
Q7L1Q6
Q96ND8
ZN583_HUMAN
Zinc finger protein L3-5
Homo
<M><S><K><D><L><V><T><F><G><D><V><A><V><N><F><S><Q><E><E><W><E><W><L><N><P><A><Q><R><N><L><Y><R><K><V><M><L><E><N><Y><R><S><L><V><S><L><G><V><S><V><S><K><P><D><V><I><S><L><L><E><Q><G><K><E><P><W><M><V><K><K><E><G><T><R><G><P><C><P><D><W><E><Y><V><F><K><N><S><E><F><S><S><K><Q><E><T><Y><E><E><S><S><K><V><V><T><V><G><A><R><H><L><S><Y><S><L><D><Y><P><S><L><R><E><D><C><Q><S><E><D><W><Y><K><N><Q><L><G><S><Q><E><V><H><L><S><Q><L><I><I><T><H><K><E><I><L><P><E><V><Q><N><K><E><Y><N><K><S><W><Q><T><F><H><Q><D><T><I><F><D><I><Q><Q><S><F><P><T><K><E><K><A><H><K><H><E><P><Q><K><K><S><Y><R><K><K><S><V><E><M><K><H><R><K><V><Y><V><E><K><K><L><L><K><C><N><D><C><E><K><V><F><N><Q><S><S><S><L><T><L><H><Q><R><I><H><T><G><E><K><P><Y><A><C><V><E><C><G><K><T><F><S><Q><S><A><N><L><A><Q><H><K><R><I><H><T><G><E><K><P><Y><E><C><K><E><C><R><K><A><F><S><Q><N><A><H><L><A><Q><H><Q><R><V><H><T><G><E><K><P><Y><Q><C><K><E><C><K><K><A><F><S><Q><I><A><H><L><T><Q><H><Q><R><V><H><T><G><E><R><P><F><E><C><I><E><C><G><K><A><F><S><N><G><S><F><L><A><Q><H><Q><R><I><H><T><G><E><K><P><Y><V><C><N><V><C><G><K><A><F><S><H><R><G><Y><L><I><V><H><Q><R><I><H><T><G><E><R><P><Y><E><C><K><E><C><R><K><A><F><S><Q><Y><A><H><L><A><Q><H><Q><R><V><H><T><G><E><K><P><Y><E><C><K><V><C><R><K><A><F><S><Q><I><A><Y><L><D><Q><H><Q><R><V><H><T><G><E><K><P><Y><E><C><I><E><C><G><K><A><F><S><N><S><S><S><L><A><Q><H><Q><R><S><H><T><G><E><K><P><Y><M><C><K><E><C><R><K><T><F><S><Q><N><A><G><L><A><Q><H><Q><R><I><H><T><G><E><K><P><Y><E><C><N><V><C><G><K><A><F><S><Y><S><G><S><L><T><L><H><Q><R><I><H><T><G><E><R><P><Y><E><C><K><D><C><R><K><S><F><R><Q><R><A><H><L><A><H><H><E><R><I><H><T><M><E><S><F><L><T><L><S><S><P><S><P><S><T><S><N><Q><L><P><R><P><V><G><F><I><S>
May be involved in transcriptional regulation.<BOP>
Q96ND8
Q14186
TFDP1_HUMAN
E2F dimerization partner 1
Homo
<M><A><K><D><A><G><L><I><E><A><N><G><E><L><K><V><F><I><D><Q><N><L><S><P><G><K><G><V><V><S><L><V><A><V><H><P><S><T><V><N><P><L><G><K><Q><L><L><P><K><T><F><G><Q><S><N><V><N><I><A><Q><Q><V><V><I><G><T><P><Q><R><P><A><A><S><N><T><L><V><V><G><S><P><H><T><P><S><T><H><F><A><S><Q><N><Q><P><S><D><S><S><P><W><S><A><G><K><R><N><R><K><G><E><K><N><G><K><G><L><R><H><F><S><M><K><V><C><E><K><V><Q><R><K><G><T><T><S><Y><N><E><V><A><D><E><L><V><A><E><F><S><A><A><D><N><H><I><L><P><N><E><S><A><Y><D><Q><K><N><I><R><R><R><V><Y><D><A><L><N><V><L><M><A><M><N><I><I><S><K><E><K><K><E><I><K><W><I><G><L><P><T><N><S><A><Q><E><C><Q><N><L><E><V><E><R><Q><R><R><L><E><R><I><K><Q><K><Q><S><Q><L><Q><E><L><I><L><Q><Q><I><A><F><K><N><L><V><Q><R><N><R><H><A><E><Q><Q><A><S><R><P><P><P><P><N><S><V><I><H><L><P><F><I><I><V><N><T><S><K><K><T><V><I><D><C><S><I><S><N><D><K><F><E><Y><L><F><N><F><D><N><T><F><E><I><H><D><D><I><E><V><L><K><R><M><G><M><A><C><G><L><E><S><G><S><C><S><A><E><D><L><K><M><A><R><S><L><V><P><K><A><L><E><P><Y><V><T><E><M><A><Q><G><T><V><G><G><V><F><I><T><T><A><G><S><T><S><N><G><T><R><F><S><A><S><D><L><T><N><G><A><D><G><M><L><A><T><S><S><N><G><S><Q><Y><S><G><S><R><V><E><T><P><V><S><Y><V><G><E><D><D><E><E><D><D><D><F><N><E><N><D><E><D><D>
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication . The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters .<BOP>
Q14186
P61981
1433G_HUMAN
14-3-3 protein gamma, N-terminally processed
Homo
<M><V><D><R><E><Q><L><V><Q><K><A><R><L><A><E><Q><A><E><R><Y><D><D><M><A><A><A><M><K><N><V><T><E><L><N><E><P><L><S><N><E><E><R><N><L><L><S><V><A><Y><K><N><V><V><G><A><R><R><S><S><W><R><V><I><S><S><I><E><Q><K><T><S><A><D><G><N><E><K><K><I><E><M><V><R><A><Y><R><E><K><I><E><K><E><L><E><A><V><C><Q><D><V><L><S><L><L><D><N><Y><L><I><K><N><C><S><E><T><Q><Y><E><S><K><V><F><Y><L><K><M><K><G><D><Y><Y><R><Y><L><A><E><V><A><T><G><E><K><R><A><T><V><V><E><S><S><E><K><A><Y><S><E><A><H><E><I><S><K><E><H><M><Q><P><T><H><P><I><R><L><G><L><A><L><N><Y><S><V><F><Y><Y><E><I><Q><N><A><P><E><Q><A><C><H><L><A><K><T><A><F><D><D><A><I><A><E><L><D><T><L><N><E><D><S><Y><K><D><S><T><L><I><M><Q><L><L><R><D><N><L><T><L><W><T><S><D><Q><Q><D><D><D><G><G><E><G><N><N>
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<BOP>
P61981
Q8WUZ0
BCL7C_HUMAN
B-cell CLL/lymphoma 7 protein family member C
Homo
<M><A><G><R><T><V><R><A><E><T><R><S><R><A><K><D><D><I><K><K><V><M><A><T><I><E><K><V><R><R><W><E><K><R><W><V><T><V><G><D><T><S><L><R><I><F><K><W><V><P><V><V><D><P><Q><E><E><E><R><R><R><A><G><G><G><A><E><R><S><R><G><R><E><R><R><G><R><G><A><S><P><R><G><G><G><P><L><I><L><L><D><L><N><D><E><N><S><N><Q><S><F><H><S><E><G><S><L><Q><K><G><T><E><P><S><P><G><G><T><P><Q><P><S><R><P><V><S><P><A><G><P><P><E><G><V><P><E><E><A><Q><P><P><R><L><G><Q><E><R><D><P><G><G><I><T><A><G><S><T><D><E><P><P><M><L><T><K><E><E><P><V><P><E><L><L><E><A><E><A><P><E><A><Y><P><V><F><E><P><V><P><P><V><P><E><A><A><Q><G><D><T><E><D><S><E><G><A><P><P><L><K><R><I><C><P><N><A><P><D><P>
May play an anti-apoptotic role.<BOP>
Q8WUZ0
Q96PS8
AQP10_HUMAN
Small intestine aquaporin
Homo
<M><V><F><T><Q><A><P><A><E><I><M><G><H><L><R><I><R><S><L><L><A><R><Q><C><L><A><E><F><L><G><V><F><V><L><M><L><L><T><Q><G><A><V><A><Q><A><V><T><S><G><E><T><K><G><N><F><F><T><M><F><L><A><G><S><L><A><V><T><I><A><I><Y><V><G><G><N><V><S><G><A><H><L><N><P><A><F><S><L><A><M><C><I><V><G><R><L><P><W><V><K><L><P><I><Y><I><L><V><Q><L><L><S><A><F><C><A><S><G><A><T><Y><V><L><Y><H><D><A><L><Q><N><Y><T><G><G><N><L><T><V><T><G><P><K><E><T><A><S><I><F><A><T><Y><P><A><P><Y><L><S><L><N><N><G><F><L><D><Q><V><L><G><T><G><M><L><I><V><G><L><L><A><I><L><D><R><R><N><K><G><V><P><A><G><L><E><P><V><V><V><G><M><L><I><L><A><L><G><L><S><M><G><A><N><C><G><I><P><L><N><P><A><R><D><L><G><P><R><L><F><T><Y><V><A><G><W><G><P><E><V><F><S><A><G><N><G><W><W><W><V><P><V><V><A><P><L><V><G><A><T><V><G><T><A><T><Y><Q><L><L><V><A><L><H><H><P><E><G><P><E><P><A><Q><D><L><V><S><A><Q><H><K><A><S><E><L><E><T><P><A><S><A><Q><M><L><E><C><K><L>
Water channel that mediates water transport across cell membranes, but that is not permeable to glycerol.<BOP>
Q96PS8
P08579
RU2B_HUMAN
U2 small nuclear ribonucleoprotein B''
Homo
<M><D><I><R><P><N><H><T><I><Y><I><N><N><M><N><D><K><I><K><K><E><E><L><K><R><S><L><Y><A><L><F><S><Q><F><G><H><V><V><D><I><V><A><L><K><T><M><K><M><R><G><Q><A><F><V><I><F><K><E><L><G><S><S><T><N><A><L><R><Q><L><Q><G><F><P><F><Y><G><K><P><M><R><I><Q><Y><A><K><T><D><S><D><I><I><S><K><M><R><G><T><F><A><D><K><E><K><K><K><E><K><K><K><A><K><T><V><E><Q><T><A><T><T><T><N><K><K><P><G><Q><G><T><P><N><S><A><N><T><Q><G><N><S><T><P><N><P><Q><V><P><D><Y><P><P><N><Y><I><L><F><L><N><N><L><P><E><E><T><N><E><M><M><L><S><M><L><F><N><Q><F><P><G><F><K><E><V><R><L><V><P><G><R><H><D><I><A><F><V><E><F><E><N><D><G><Q><A><G><A><A><R><D><A><L><Q><G><F><K><I><T><P><S><H><A><M><K><I><T><Y><A><K><K>
Involved in pre-mRNA splicing as component of the spliceosome . Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA .<BOP>
P08579
Q14746
COG2_HUMAN
Low density lipoprotein receptor defect C-complementing protein
Homo
<M><E><K><S><R><M><N><L><P><K><G><P><D><T><L><C><F><D><K><D><E><F><M><K><E><D><F><D><V><D><H><F><V><S><D><C><R><K><R><V><Q><L><E><E><L><R><D><D><L><E><L><Y><Y><K><L><L><K><T><A><M><V><E><L><I><N><K><D><Y><A><D><F><V><N><L><S><T><N><L><V><G><M><D><K><A><L><N><Q><L><S><V><P><L><G><Q><L><R><E><E><V><L><S><L><R><S><S><V><S><E><G><I><R><A><V><D><E><R><M><S><K><Q><E><D><I><R><K><K><K><M><C><V><L><R><L><I><Q><V><I><R><S><V><E><K><I><E><K><I><L><N><S><Q><S><S><K><E><T><S><A><L><E><A><S><S><P><L><L><T><G><Q><I><L><E><R><I><A><T><E><F><N><Q><L><Q><F><H><A><V><Q><S><K><G><M><P><L><L><D><K><V><R><P><R><I><A><G><I><T><A><M><L><Q><Q><S><L><E><G><L><L><L><E><G><L><Q><T><S><D><V><D><I><I><R><H><C><L><R><T><Y><A><T><I><D><K><T><R><D><A><E><A><L><V><G><Q><V><L><V><K><P><Y><I><D><E><V><I><I><E><Q><F><V><E><S><H><P><N><G><L><Q><V><M><Y><N><K><L><L><E><F><V><P><H><H><C><R><L><L><R><E><V><T><G><G><A><I><S><S><E><K><G><N><T><V><P><G><Y><D><F><L><V><N><S><V><W><P><Q><I><V><Q><G><L><E><E><K><L><P><S><L><F><N><P><G><N><P><D><A><F><H><E><K><Y><T><I><S><M><D><F><V><R><R><L><E><R><Q><C><G><S><Q><A><S><V><K><R><L><R><A><H><P><A><Y><H><S><F><N><K><K><W><N><L><P><V><Y><F><Q><I><R><F><R><E><I><A><G><S><L><E><A><A><L><T><D><V><L><E><D><A><P><A><E><S><P><Y><C><L><L><A><S><H><R><T><W><S><S><L><R><R><C><W><S><D><E><M><F><L><P><L><L><V><H><R><L><W><R><L><T><L><Q><I><L><A><R><Y><S><V><F><V><N><E><L><S><L><R><P><I><S><N><E><S><P><K><E><I><K><K><P><L><V><T><G><S><K><E><P><S><I><T><Q><G><N><T><E><D><Q><G><S><G><P><S><E><T><K><P><V><V><S><I><S><R><T><Q><L><V><Y><V><V><A><D><L><D><K><L><Q><E><Q><L><P><E><L><L><E><I><I><K><P><K><L><E><M><I><G><F><K><N><F><S><S><I><S><A><A><L><E><D><S><Q><S><S><F><S><A><C><V><P><S><L><S><S><K><I><I><Q><D><L><S><D><S><C><F><G><F><L><K><S><A><L><E><V><P><R><L><Y><R><R><T><N><K><E><V><P><T><T><A><S><S><Y><V><D><S><A><L><K><P><L><F><Q><L><Q><S><G><H><K><D><K><L><K><Q><A><I><I><Q><Q><W><L><E><G><T><L><S><E><S><T><H><K><Y><Y><E><T><V><S><D><V><L><N><S><V><K><K><M><E><E><S><L><K><R><L><K><Q><A><R><K><T><T><P><A><N><P><V><G><P><S><G><G><M><S><D><D><D><K><I><R><L><Q><L><A><L><D><V><E><Y><L><G><E><Q><I><Q><K><L><G><L><Q><A><S><D><I><K><S><F><S><A><L><A><E><L><V><A><A><A><K><D><Q><A><T><A><E><Q><P>
Required for normal Golgi morphology and function.<BOP>
Q14746
O95399
UTS2_HUMAN
Urotensin II
Homo
<M><Y><K><L><A><S><C><C><L><L><F><I><G><F><L><N><P><L><L><S><L><P><L><L><D><S><R><E><I><S><F><Q><L><S><A><P><H><E><D><A><R><L><T><P><E><E><L><E><R><A><S><L><L><Q><I><L><P><E><M><L><G><A><E><R><G><D><I><L><R><K><A><D><S><S><T><N><I><F><N><P><R><G><N><L><R><K><F><Q><D><F><S><G><Q><D><P><N><I><L><L><S><H><L><L><A><R><I><W><K><P><Y><K><K><R><E><T><P><D><C><F><W><K><Y><C><V>
Highly potent vasoconstrictor.<BOP>
O95399
Q969V1
MCHR2_HUMAN
MCH-2R
Homo
<M><N><P><F><H><A><S><C><W><N><T><S><A><E><L><L><N><K><S><W><N><K><E><F><A><Y><Q><T><A><S><V><V><D><T><V><I><L><P><S><M><I><G><I><I><C><S><T><G><L><V><G><N><I><L><I><V><F><T><I><I><R><S><R><K><K><T><V><P><D><I><Y><I><C><N><L><A><V><A><D><L><V><H><I><V><G><M><P><F><L><I><H><Q><W><A><R><G><G><E><W><V><F><G><G><P><L><C><T><I><I><T><S><L><D><T><C><N><Q><F><A><C><S><A><I><M><T><V><M><S><V><D><R><Y><F><A><L><V><Q><P><F><R><L><T><R><W><R><T><R><Y><K><T><I><R><I><N><L><G><L><W><A><A><S><F><I><L><A><L><P><V><W><V><Y><S><K><V><I><K><F><K><D><G><V><E><S><C><A><F><D><L><T><S><P><D><D><V><L><W><Y><T><L><Y><L><T><I><T><T><F><F><F><P><L><P><L><I><L><V><C><Y><I><L><I><L><C><Y><T><W><E><M><Y><Q><Q><N><K><D><A><R><C><C><N><P><S><V><P><K><Q><R><V><M><K><L><T><K><M><V><L><V><L><V><V><V><F><I><L><S><A><A><P><Y><H><V><I><Q><L><V><N><L><Q><M><E><Q><P><T><L><A><F><Y><V><G><Y><Y><L><S><I><C><L><S><Y><A><S><S><S><I><N><P><F><L><Y><I><L><L><S><G><N><F><Q><K><R><L><P><Q><I><Q><R><R><A><T><E><K><E><I><N><N><M><G><N><T><L><K><S><H><F>
Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.<BOP>
Q969V1
Q9P2J3
KLHL9_HUMAN
Kelch-like protein 9
Homo
<M><K><V><S><L><G><N><G><E><M><G><V><S><A><H><L><Q><P><C><K><A><G><T><T><R><F><F><T><S><N><T><H><S><S><V><V><L><Q><G><F><D><Q><L><R><I><E><G><L><L><C><D><V><T><L><V><P><G><D><G><D><E><I><F><P><V><H><R><A><M><M><A><S><A><S><D><Y><F><K><A><M><F><T><G><G><M><K><E><Q><D><L><M><C><I><K><L><H><G><V><N><K><V><G><L><K><K><I><I><D><F><I><Y><T><A><K><L><S><L><N><M><D><N><L><Q><D><T><L><E><A><A><S><F><L><Q><I><L><P><V><L><D><F><C><K><V><F><L><I><S><G><V><S><L><D><N><C><V><E><V><G><R><I><A><N><T><Y><N><L><I><E><V><D><K><Y><V><N><N><F><I><L><K><N><F><P><A><L><L><S><T><G><E><F><L><K><L><P><F><E><R><L><A><F><V><L><S><S><N><S><L><K><H><C><T><E><L><E><L><F><K><A><A><C><R><W><L><R><L><E><D><P><R><M><D><Y><A><A><K><L><M><K><N><I><R><F><P><L><M><T><P><Q><D><L><I><N><Y><V><Q><T><V><D><F><M><R><T><D><N><T><C><V><N><L><L><L><E><A><S><N><Y><Q><M><M><P><Y><M><Q><P><V><M><Q><S><D><R><T><A><I><R><S><D><S><T><H><L><V><T><L><G><G><V><L><R><Q><Q><L><V><V><S><K><E><L><R><M><Y><D><E><R><A><Q><E><W><R><S><L><A><P><M><D><A><P><R><Y><Q><H><G><I><A><V><I><G><N><F><L><Y><V><V><G><G><Q><S><N><Y><D><T><K><G><K><T><A><V><D><T><V><F><R><F><D><P><R><Y><N><K><W><M><Q><V><A><S><L><N><E><K><R><T><F><F><H><L><S><A><L><K><G><H><L><Y><A><V><G><G><R><S><A><A><G><E><L><A><T><V><E><C><Y><N><P><R><M><N><E><W><S><Y><V><A><K><M><S><E><P><H><Y><G><H><A><G><T><V><Y><G><G><L><M><Y><I><S><G><G><I><T><H><D><T><F><Q><N><E><L><M><C><F><D><P><D><T><D><K><W><M><Q><K><A><P><M><T><T><V><R><G><L><H><C><M><C><T><V><G><D><K><L><Y><V><I><G><G><N><H><F><R><G><T><S><D><Y><D><D><V><L><S><C><E><Y><Y><S><P><T><L><D><Q><W><T><P><I><A><A><M><L><R><G><Q><S><D><V><G><V><A><V><F><E><N><K><I><Y><V><V><G><G><Y><S><W><N><N><R><C><M><V><E><I><V><Q><K><Y><D><P><E><K><D><E><W><H><K><V><F><D><L><P><E><S><L><G><G><I><R><A><C><T><L><T><V><F><P><P><E><E><N><P><G><S><P><S><R><E><S><P><L><S><A><P><S><D><H><S>
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.<BOP>
Q9P2J3
Q9H9V4
RN122_HUMAN
RING finger protein 122
Homo
<M><H><P><F><Q><W><C><N><G><C><F><C><G><L><G><L><V><S><T><N><K><S><C><S><M><P><P><I><S><F><Q><D><L><P><L><N><I><Y><M><V><I><F><G><T><G><I><F><V><F><M><L><S><L><I><F><C><C><Y><F><I><S><K><L><R><N><Q><A><Q><S><E><R><Y><G><Y><K><E><V><V><L><K><G><D><A><K><K><L><Q><L><Y><G><Q><T><C><A><V><C><L><E><D><F><K><G><K><D><E><L><G><V><L><P><C><Q><H><A><F><H><R><K><C><L><V><K><W><L><E><V><R><C><V><C><P><M><C><N><K><P><I><A><S><P><S><E><A><T><Q><N><I><G><I><L><L><D><E><L><V>
May induce necrosis and apoptosis. May play a role in cell viability.<BOP>
Q9H9V4
Q96RD1
OR6C1_HUMAN
OST267
Homo
<M><R><N><H><T><E><I><T><E><F><I><L><L><G><L><T><D><D><P><N><F><Q><V><V><I><F><V><F><L><L><I><T><Y><M><L><S><I><T><G><N><L><T><L><I><T><I><T><L><L><D><S><H><L><Q><T><P><M><Y><F><F><L><R><N><F><S><I><L><E><I><S><F><T><T><V><S><I><P><K><F><L><G><N><I><I><S><G><D><K><T><I><S><F><N><N><C><I><V><Q><L><F><F><F><I><L><L><G><V><T><E><F><Y><L><L><A><A><M><S><Y><D><R><Y><V><A><I><C><K><P><L><H><C><L><S><I><M><N><R><R><V><C><T><L><L><V><F><T><S><W><L><V><S><F><L><I><I><F><P><A><L><M><L><L><L><K><L><H><Y><C><R><S><N><I><I><D><H><F><T><C><D><Y><F><P><L><L><Q><L><A><C><S><D><T><K><F><L><E><V><M><G><F><S><C><A><A><F><T><L><M><F><T><L><A><L><I><F><L><S><Y><I><Y><I><I><R><T><I><L><R><I><P><S><T><S><Q><R><T><K><A><F><S><T><C><S><S><H><M><V><V><V><S><I><S><Y><G><S><C><I><F><M><Y><I><K><P><S><A><K><D><R><V><S><L><S><K><G><V><A><I><L><N><T><S><V><A><P><M><M><N><P><F><I><Y><S><L><R><N><Q><Q><V><K><Q><A><F><I><N><M><A><R><K><T><V><F><F><T><S><T>
Odorant receptor.<BOP>
Q96RD1
Q8N2H9
PELI3_HUMAN
RING-type E3 ubiquitin transferase pellino homolog 3
Homo
<M><V><L><E><G><N><P><E><V><G><S><P><R><T><S><D><L><Q><H><R><G><N><K><G><S><C><V><L><S><S><P><G><E><D><A><Q><P><G><E><E><P><I><K><Y><G><E><L><I><V><L><G><C><C><E><E><G><G><E><E><T><E><A><Q><R><G><E><V><T><G><P><R><A><H><S><C><Y><N><G><C><L><A><S><G><D><K><G><R><R><R><S><R><L><A><L><S><R><R><S><H><A><N><G><V><K><P><D><V><M><H><H><I><S><T><P><L><V><S><K><A><L><S><N><R><G><Q><H><S><I><S><Y><T><L><S><R><S><H><S><V><I><V><E><Y><T><H><D><S><D><T><D><M><F><Q><I><G><R><S><T><E><N><M><I><D><F><V><V><T><D><T><S><P><G><G><G><A><A><E><G><P><S><A><Q><S><T><I><S><R><Y><A><C><R><I><L><C><D><R><R><P><P><Y><T><A><R><I><Y><A><A><G><F><D><A><S><S><N><I><F><L><G><E><R><A><A><K><W><R><T><P><D><G><L><M><D><G><L><T><T><N><G><V><L><V><M><H><P><A><G><G><F><S><E><D><S><A><P><G><V><W><R><E><I><S><V><C><G><N><V><Y><T><L><R><D><S><R><S><A><Q><Q><R><G><K><L><V><E><N><E><S><N><V><L><Q><D><G><S><L><I><D><L><C><G><A><T><L><L><W><R><T><P><A><G><L><L><R><A><P><T><L><K><Q><L><E><A><Q><R><Q><E><A><N><A><A><R><P><Q><C><P><V><G><L><S><T><L><A><F><P><S><P><A><R><G><R><T><A><P><D><K><Q><Q><P><W><V><Y><V><R><C><G><H><V><H><G><Y><H><G><W><G><C><R><R><E><R><G><P><Q><E><R><E><C><P><L><C><R><L><V><G><P><Y><V><P><L><W><L><G><Q><E><A><G><L><C><L><D><P><G><P><P><S><H><A><F><A><P><C><G><H><V><C><S><E><K><T><A><R><Y><W><A><Q><T><P><L><P><H><G><T><H><A><F><H><A><A><C><P><F><C><G><A><W><L><T><G><E><H><G><C><V><R><L><I><F><Q><G><P><L><D>
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.<BOP>
Q8N2H9
P0C6T2
OST4_HUMAN
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4
Homo
<M><I><T><D><V><Q><L><A><I><F><A><N><M><L><G><V><S><L><F><L><L><V><V><L><Y><H><Y><V><A><V><N><N><P><K><K><Q><E>
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation . N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes.<BOP>
P0C6T2
P08493
MGP_HUMAN
Cell growth-inhibiting gene 36 protein
Homo
<M><K><S><L><I><L><L><A><I><L><A><A><L><A><V><V><T><L><C><Y><E><S><H><E><S><M><E><S><Y><E><L><N><P><F><I><N><R><R><N><A><N><T><F><I><S><P><Q><Q><R><W><R><A><K><V><Q><E><R><I><R><E><R><S><K><P><V><H><E><L><N><R><E><A><C><D><D><Y><R><L><C><E><R><Y><A><M><V><Y><G><Y><N><A><A><Y><N><R><Y><F><R><K><R><R><G><T><K>
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.<BOP>
P08493
Q9Y399
RT02_HUMAN
Mitochondrial small ribosomal subunit protein uS2m
Homo
<M><A><T><S><S><A><A><L><P><R><I><L><G><A><G><A><R><A><P><S><R><W><L><G><F><L><G><K><A><T><P><R><P><A><R><P><S><R><R><T><L><G><S><A><T><A><L><M><I><R><E><S><E><D><S><T><D><F><N><D><K><I><L><N><E><P><L><K><H><S><D><F><F><N><V><K><E><L><F><S><V><R><S><L><F><D><A><R><V><H><L><G><H><K><A><G><C><R><H><R><F><M><E><P><Y><I><F><G><S><R><L><D><H><D><I><I><D><L><E><Q><T><A><T><H><L><Q><L><A><L><N><F><T><A><H><M><A><Y><R><K><G><I><I><L><F><I><S><R><N><R><Q><F><S><Y><L><I><E><N><M><A><R><D><C><G><E><Y><A><H><T><R><Y><F><R><G><G><M><L><T><N><A><R><L><L><F><G><P><T><V><R><L><P><D><L><I><I><F><L><H><T><L><N><N><I><F><E><P><H><V><A><V><R><D><A><A><K><M><N><I><P><T><V><G><I><V><D><T><N><C><N><P><C><L><I><T><Y><P><V><P><G><N><D><D><S><P><L><A><V><H><L><Y><C><R><L><F><Q><T><A><I><T><R><A><K><E><K><R><Q><Q><V><E><A><L><Y><R><L><Q><G><Q><K><E><P><G><D><Q><G><P><A><H><P><P><G><A><D><M><S><H><S><L>
Required for mitoribosome formation and stability, and mitochondrial translation.<BOP>
Q9Y399
B4DXR9
ZN732_HUMAN
Zinc finger protein 732
Homo
<M><E><L><L><T><F><R><D><V><A><I><E><F><S><P><E><E><W><K><C><L><D><P><A><Q><Q><N><L><Y><R><D><V><M><L><E><N><Y><R><N><L><I><S><L><G><V><A><I><S><N><P><D><L><V><I><Y><L><E><Q><R><K><E><P><Y><K><V><K><I><H><E><T><V><A><K><H><P><A><V><C><S><H><F><T><Q><D><F><L><P><V><Q><G><I><E><D><S><F><H><K><L><I><L><R><R><Y><E><K><C><G><H><E><N><L><E><L><R><K><S><C><K><R><K><V><Q><K><G><G><Y><N><E><F><N><Q><C><L><S><T><I><Q><S><K><I><F><Q><C><N><V><H><V><K><V><F><S><T><F><S><N><S><N><Q><R><R><I><R><H><T><G><E><K><H><F><K><E><C><G><K><S><F><Q><K><F><S><D><L><T><Q><H><Q><G><I><H><A><G><E><K><P><Y><T><C><E><E><C><G><K><D><F><K><W><Y><L><I><F><N><E><Y><E><I><I><H><T><G><E><K><P><F><T><C><E><E><C><G><N><I><F><T><T><S><S><N><F><A><K><H><K><V><H><T><G><E><K><S><Y><K><Y><E><E><C><G><K><A><F><N><R><S><S><T><L><T><K><H><K><R><I><H><A><E><E><K><P><F><T><C><E><E><C><G><K><I><I><T><S><S><S><N><V><A><K><H><K><K><I><H><T><G><E><K><L><Y><K><C><Q><E><C><G><K><V><F><N><R><S><T><T><L><T><K><H><N><R><I><H><T><G><E><K><P><Y><T><C><E><E><C><G><K><A><F><S><R><S><S><V><L><N><E><H><K><R><I><H><T><G><E><K><P><Y><K><C><E><Q><C><G><K><A><F><R><Q><S><A><T><L><N><K><H><K><S><I><H><T><G><E><K><P><Y><T><C><E><E><C><G><K><A><F><S><R><F><T><T><L><N><E><H><K><R><I><H><T><G><E><R><P><H><K><C><E><E><C><G><K><A><F><G><W><S><T><D><L><N><K><H><K><I><I><H><T><G><E><K><P><Y><K><C><E><E><C><G><K><A><F><G><W><S><A><Y><L><S><K><H><K><K><I><H><T><G><E><K><P><Y><R><C><E><E><C><G><K><A><F><L><C><S><R><A><L><N><K><H><K><T><I><H><T><G><E><K><P><Y><E><C><E><E><C><G><K><A><F><G><W><S><T><Y><L><S><K><H><K><K><I><H><T><G><E><K><P><Y><R><C><E><E><C><G><K><A><F><R><R><S><R><V><L><N><K><Y><K><T><I><H><T><G><D><K><T><P><K><C><K><G><C><G><K><A><F><K><W><S><S><Y><L><N><Q><H><N><K><I><Y><T><G><E><K><L>
May be involved in transcriptional regulation.<BOP>
B4DXR9
Q5TEC6
H37_HUMAN
Histone H3-7
Homo
<M><A><R><T><K><Q><T><A><R><K><S><T><G><G><K><A><P><R><K><Q><L><A><T><K><A><A><R><K><S><A><P><A><T><G><G><V><K><K><P><H><R><Y><R><P><G><T><V><A><L><R><E><I><R><R><Y><Q><K><S><T><E><L><L><I><R><K><L><P><F><Q><R><L><V><R><E><I><A><Q><E><F><K><T><D><L><R><F><Q><S><S><A><V><M><A><L><Q><E><A><R><E><A><Y><L><V><G><L><F><E><D><T><N><L><C><A><I><H><A><K><R><V><T><I><M><P><K><D><I><Q><L><V><S><R><I><R><G><E><R><A>
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<BOP>
Q5TEC6
Q02575
HEN1_HUMAN
Nescient helix loop helix 1
Homo
<M><M><L><N><S><D><T><M><E><L><D><L><P><P><T><H><S><E><T><E><S><G><F><S><D><C><G><G><G><A><G><P><D><G><A><G><P><G><G><P><G><G><G><Q><A><R><G><P><E><P><G><E><P><G><R><K><D><L><Q><H><L><S><R><E><E><R><R><R><R><R><R><A><T><A><K><Y><R><T><A><H><A><T><R><E><R><I><R><V><E><A><F><N><L><A><F><A><E><L><R><K><L><L><P><T><L><P><P><D><K><K><L><S><K><I><E><I><L><R><L><A><I><C><Y><I><S><Y><L><N><H><V><L><D><V>
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.<BOP>
Q02575
Q8N972
ZN709_HUMAN
Zinc finger protein 709
Homo
<M><D><S><V><V><F><E><D><V><A><V><N><F><T><Q><E><E><W><A><L><L><G><P><S><Q><K><K><L><Y><R><D><V><M><Q><E><T><F><V><N><L><A><S><I><G><E><N><W><E><E><K><N><I><E><D><H><K><N><Q><G><R><K><L><R><S><H><M><V><E><R><L><C><E><R><K><E><G><S><Q><F><G><E><T><I><S><Q><T><P><N><P><K><P><N><K><K><T><F><T><R><V><K><P><Y><E><C><S><V><C><G><K><D><Y><M><C><H><S><S><L><N><R><H><M><R><S><H><T><E><H><R><S><Y><E><Y><H><K><Y><G><E><K><S><Y><E><C><K><E><C><G><K><R><F><S><F><R><S><S><F><R><I><H><E><R><T><H><T><G><E><K><P><Y><K><C><K><Q><C><G><K><A><F><S><W><P><S><S><F><Q><I><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><E><C><G><K><A><F><I><Y><H><T><T><F><R><G><H><M><R><M><H><T><G><E><K><P><Y><K><C><K><E><C><G><K><T><F><S><H><P><S><S><F><R><N><H><E><R><T><H><S><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><R><Y><Y><Q><T><F><Q><I><H><E><R><T><H><T><G><E><K><P><Y><Q><C><K><Q><C><G><K><A><L><S><C><P><T><S><F><R><S><H><E><R><I><H><T><G><E><K><P><Y><K><C><K><K><C><G><K><A><F><S><F><P><S><S><F><R><K><H><E><R><I><H><T><G><E><K><P><Y><D><C><K><E><C><G><K><A><F><I><S><L><P><S><Y><R><R><H><M><I><M><H><T><G><N><G><P><Y><K><C><K><E><C><G><K><A><F><D><C><P><S><S><F><Q><I><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><F><R><M><H><E><R><T><H><T><G><E><K><P><H><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><V><R><I><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><F><R><M><H><E><R><I><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><F><S><S><S><F><R><M><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><F><R><M><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><I><R><I><H><E><R><T><H><T><G><E><K><P><Y><E><C><K><Q><C><G><K><A><F><S><C><S><S><S><V><R><M><H><E><R><T><H><T><G><V><K><P><Y><E><C><K><Q><C><D><K><A><F><S><C><S><R><S><F><R><I><H><E><R><T><H><T><G><E><K><P><Y><A><C><Q><Q><C><G><K><A><F><K><C><S><R><S><F><R><I><H><E><R><V><H><S><G><E>
May be involved in transcriptional regulation.<BOP>
Q8N972