accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P32969 | RL9_HUMAN | Large ribosomal subunit protein uL6 | Homo | <M><K><T><I><L><S><N><Q><T><V><D><I><P><E><N><V><D><I><T><L><K><G><R><T><V><I><V><K><G><P><R><G><T><L><R><R><D><F><N><H><I><N><V><E><L><S><L><L><G><K><K><K><K><R><L><R><V><D><K><W><W><G><N><R><K><E><L><A><T><V><R><T><I><C><S><H><V><Q><N><M><I><K><G><V><T><L><G><F><R><Y><K><M><R><S><V><Y><A><H><F><P><I><N><V><V><I><Q><E... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP> | P32969 |
P49336 | CDK8_HUMAN | Protein kinase K35 | Homo | <M><D><Y><D><F><K><V><K><L><S><S><E><R><E><R><V><E><D><L><F><E><Y><E><G><C><K><V><G><R><G><T><Y><G><H><V><Y><K><A><K><R><K><D><G><K><D><D><K><D><Y><A><L><K><Q><I><E><G><T><G><I><S><M><S><A><C><R><E><I><A><L><L><R><E><L><K><H><P><N><V><I><S><L><Q><K><V><F><L><S><H><A><D><R><K><V><W><L><L><F><D><Y><A><E><H><D><L><W><H><I... | Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoter... | P49336 |
Q12796 | PNRC1_HUMAN | Protein B4-2 | Homo | <M><T><V><V><S><V><P><Q><R><E><P><L><V><L><G><G><R><L><A><P><L><G><F><S><S><R><G><Y><F><G><A><L><P><M><V><T><T><A><P><P><P><L><P><R><I><P><D><P><R><A><L><P><P><T><L><F><L><P><H><F><L><G><G><D><G><P><C><L><T><P><Q><P><R><A><P><A><A><L><P><N><R><S><L><A><V><A><G><G><T><P><R><A><A><P><K><K><R><R><K><K><K><V><R><A><S><P><A... | Nuclear receptor coactivator. May play a role in signal transduction.<BOP> | Q12796 |
Q8IZN3 | ZDH14_HUMAN | Zinc finger DHHC domain-containing protein 14 | Homo | <M><P><P><G><G><G><G><P><M><K><D><C><E><Y><S><Q><I><S><T><H><S><S><S><P><M><E><S><P><H><K><K><K><K><I><A><A><R><R><K><W><E><V><F><P><G><R><N><K><F><F><C><N><G><R><I><M><M><A><R><Q><T><G><V><F><Y><L><T><L><V><L><I><L><V><T><S><G><L><F><F><A><F><D><C><P><Y><L><A><V><K><I><T><P><A><I><P><A><V><A><G><I><L><F><F><F><V><M><G... | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and thereby regulate G protein-coupled receptor signaling . May play a role in cell differentiation and apoptosis .<BOP> | Q8IZN3 |
P52737 | ZN136_HUMAN | Zinc finger protein 136 | Homo | <M><D><S><V><A><F><E><D><V><D><V><N><F><T><Q><E><E><W><A><L><L><D><P><S><Q><K><N><L><Y><R><D><V><M><W><E><T><M><R><N><L><A><S><I><G><K><K><W><K><D><Q><N><I><K><D><H><Y><K><H><R><G><R><N><L><R><S><H><M><L><E><R><L><Y><Q><T><K><D><G><S><Q><R><G><G><I><F><S><Q><F><A><N><Q><N><L><S><K><K><I><P><G><V><K><L><C><E><S><I><V><Y... | May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.<BOP> | P52737 |
Q9HC21 | TPC_HUMAN | Solute carrier family 25 member 19 | Homo | <M><V><G><Y><D><P><K><P><D><G><R><N><N><T><K><F><Q><V><A><V><A><G><S><V><S><G><L><V><T><R><A><L><I><S><P><F><D><V><I><K><I><R><F><Q><L><Q><H><E><R><L><S><R><S><D><P><S><A><K><Y><H><G><I><L><Q><A><S><R><Q><I><L><Q><E><E><G><P><T><A><F><W><K><G><H><V><P><A><Q><I><L><S><I><G><Y><G><A><V><Q><F><L><S><F><E><M><L><T><E><L><V... | Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria.<BOP> | Q9HC21 |
P78330 | SERB_HUMAN | O-phosphoserine phosphohydrolase | Homo | <M><V><S><H><S><E><L><R><K><L><F><Y><S><A><D><A><V><C><F><D><V><D><S><T><V><I><R><E><E><G><I><D><E><L><A><K><I><C><G><V><E><D><A><V><S><E><M><T><R><R><A><M><G><G><A><V><P><F><K><A><A><L><T><E><R><L><A><L><I><Q><P><S><R><E><Q><V><Q><R><L><I><A><E><Q><P><P><H><L><T><P><G><I><R><E><L><V><S><R><L><Q><E><R><N><V><Q><V><F><L... | Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine . L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neurom... | P78330 |
O15318 | RPC7_HUMAN | RNA polymerase III 32 kDa subunit | Homo | <M><A><G><N><K><G><R><G><R><A><A><Y><T><F><N><I><E><A><V><G><F><S><K><G><E><K><L><P><D><V><V><L><K><P><P><P><L><F><P><D><T><D><Y><K><P><V><P><L><K><T><G><E><G><E><E><Y><M><L><A><L><K><Q><E><L><R><E><T><M><K><R><M><P><Y><F><I><E><T><P><E><E><R><Q><D><I><E><R><Y><S><K><R><Y><M><K><V><Y><K><E><E><W><I><P><D><W><R><R><L><P... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs . May direct with other members of the RPC3/POLR3C-RPC6/POLR3F-RPC7/POLR3G subco... | O15318 |
Q7Z4V5 | HDGR2_HUMAN | Hepatoma-derived growth factor 2 | Homo | <M><P><H><A><F><K><P><G><D><L><V><F><A><K><M><K><G><Y><P><H><W><P><A><R><I><D><D><I><A><D><G><A><V><K><P><P><P><N><K><Y><P><I><F><F><F><G><T><H><E><T><A><F><L><G><P><K><D><L><F><P><Y><D><K><C><K><D><K><Y><G><K><P><N><K><R><K><G><F><N><E><G><L><W><E><I><Q><N><N><P><H><A><S><Y><S><A><P><P><P><V><S><S><S><D><S><E><A><P><E... | Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C) . Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF comple... | Q7Z4V5 |
P59780 | AP3S2_HUMAN | Sigma-adaptin 3b | Homo | <M><I><Q><A><I><L><V><F><N><N><H><G><K><P><R><L><V><R><F><Y><Q><R><F><P><E><E><I><Q><Q><Q><I><V><R><E><T><F><H><L><V><L><K><R><D><D><N><I><C><N><F><L><E><G><G><S><L><I><G><G><S><D><Y><K><L><I><Y><R><H><Y><A><T><L><Y><F><V><F><C><V><D><S><S><E><S><E><L><G><I><L><D><L><I><Q><V><F><V><E><T><L><D><K><C><F><E><N><V><C><E><L... | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-... | P59780 |
Q01196 | RUNX1_HUMAN | SL3/AKV core-binding factor alpha B subunit | Homo | <M><R><I><P><V><D><A><S><T><S><R><R><F><T><P><P><S><T><A><L><S><P><G><K><M><S><E><A><L><P><L><G><A><P><D><A><G><A><A><L><A><G><K><L><R><S><G><D><R><S><M><V><E><V><L><A><D><H><P><G><E><L><V><R><T><D><S><P><N><F><L><C><S><V><L><P><T><H><W><R><C><N><K><T><L><P><I><A><F><K><V><V><A><L><G><D><V><P><D><G><T><L><V><T><V><M><A... | Isoform AML-1L interferes with the transactivation activity of RUNX1.<BOP> | Q01196 |
Q16778 | H2B2E_HUMAN | Histone H2B.q | Homo | <M><P><E><P><A><K><S><A><P><A><P><K><K><G><S><K><K><A><V><T><K><A><Q><K><K><D><G><K><K><R><K><R><S><R><K><E><S><Y><S><I><Y><V><Y><K><V><L><K><Q><V><H><P><D><T><G><I><S><S><K><A><M><G><I><M><N><S><F><V><N><D><I><F><E><R><I><A><G><E><A><S><R><L><A><H><Y><N><K><R><S><T><I><T><S><R><E><I><Q><T><A><V><R><L><L><L><P><G><E><L... | Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<BOP> | Q16778 |
A0A0B4J272 | TVA24_HUMAN | T cell receptor alpha variable 24 | Homo | <M><E><K><N><P><L><A><A><P><L><L><I><L><W><F><H><L><D><C><V><S><S><I><L><N><V><E><Q><S><P><Q><S><L><H><V><Q><E><G><D><S><T><N><F><T><C><S><F><P><S><S><N><F><Y><A><L><H><W><Y><R><W><E><T><A><K><S><P><E><A><L><F><V><M><T><L><N><G><D><E><K><K><K><G><R><I><S><A><T><L><N><T><K><E><G><Y><S><Y><L><Y><I><K><G><S><Q><P><E><D><S... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A0B4J272 |
Q5TZ20 | OR2G6_HUMAN | Olfactory receptor 2G6 | Homo | <M><E><E><T><N><N><S><S><E><K><G><F><L><L><L><G><F><S><D><Q><P><Q><L><E><R><F><L><F><A><I><I><L><Y><F><Y><V><L><S><L><L><G><N><T><A><L><I><L><V><C><C><L><D><S><R><L><H><T><P><M><Y><F><F><L><S><N><L><S><C><V><D><I><C><F><T><T><S><V><A><P><Q><L><L><V><T><M><N><K><K><D><K><T><M><S><Y><G><G><C><V><A><Q><L><Y><V><A><M><G><L... | Odorant receptor.<BOP> | Q5TZ20 |
Q6P587 | FAHD1_HUMAN | YisK-like protein | Homo | <M><G><I><M><A><A><S><R><P><L><S><R><F><W><E><W><G><K><N><I><V><C><V><G><R><N><Y><A><D><H><V><R><E><M><R><S><A><V><L><S><E><P><V><L><F><L><K><P><S><T><A><Y><A><P><E><G><S><P><I><L><M><P><A><Y><T><R><N><L><H><H><E><L><E><L><G><V><V><M><G><K><R><C><R><A><V><P><E><A><A><A><M><D><Y><V><G><G><Y><A><L><C><L><D><M><T><A><R><D... | Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro . Also has oxaloacetate decarboxylase activity .<BOP> | Q6P587 |
O75820 | ZN189_HUMAN | Zinc finger protein 189 | Homo | <M><A><S><P><S><P><P><P><E><S><K><G><L><L><T><F><E><D><V><A><V><F><F><T><Q><E><E><W><D><Y><L><D><P><A><Q><R><S><L><Y><K><D><V><M><M><E><N><Y><G><N><L><V><S><L><D><V><L><N><R><D><K><D><E><E><P><T><V><K><Q><E><I><E><E><I><E><E><E><V><E><P><Q><G><V><I><V><T><R><I><K><S><E><I><D><Q><D><P><M><G><R><E><T><F><E><L><V><G><R><L... | May be involved in transcriptional regulation.<BOP> | O75820 |
Q96KK3 | KCNS1_HUMAN | Voltage-gated potassium channel subunit Kv9.1 | Homo | <M><L><M><L><L><V><R><G><T><H><Y><E><N><L><R><S><K><V><V><L><P><T><P><L><G><G><R><S><T><E><T><F><V><S><E><F><P><G><P><D><T><G><I><R><W><R><R><S><D><E><A><L><R><V><N><V><G><G><V><R><R><Q><L><S><A><R><A><L><A><R><F><P><G><T><R><L><G><R><L><Q><A><A><A><S><E><E><Q><A><R><R><L><C><D><D><Y><D><E><A><A><R><E><F><Y><F><D><R><H... | Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2 .<BOP> | Q96KK3 |
Q9H773 | DCTP1_HUMAN | XTP3-transactivated gene A protein | Homo | <M><S><V><A><G><G><E><I><R><G><D><T><G><G><E><D><T><A><A><P><G><R><F><S><F><S><P><E><P><T><L><E><D><I><R><R><L><H><A><E><F><A><A><E><R><D><W><E><Q><F><H><Q><P><R><N><L><L><L><A><L><V><G><E><V><G><E><L><A><E><L><F><Q><W><K><T><D><G><E><P><G><P><Q><G><W><S><P><R><E><R><A><A><L><Q><E><E><L><S><D><V><L><I><Y><L><V><A><L><A... | Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs... | Q9H773 |
Q9BXS0 | COPA1_HUMAN | Collagen-like Alzheimer amyloid plaque component | Homo | <M><L><L><K><K><H><A><G><K><G><G><G><R><E><P><R><S><E><D><P><T><P><A><E><Q><H><C><A><R><T><M><P><P><C><A><V><L><A><A><L><L><S><V><V><A><V><V><S><C><L><Y><L><G><V><K><T><N><D><L><Q><A><R><I><A><A><L><E><S><A><K><G><A><P><S><I><H><L><L><P><D><T><L><D><H><L><K><T><M><V><Q><E><K><V><E><R><L><L><A><Q><K><S><Y><E><H><M><A><K... | Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin.<BOP> | Q9BXS0 |
A0A0K0K1B3 | TVB30_HUMAN | T cell receptor beta variable 30 | Homo | <M><L><C><S><L><L><A><L><L><L><G><T><F><F><G><V><R><S><Q><T><I><H><Q><W><P><A><T><L><V><Q><P><V><G><S><P><L><S><L><E><C><T><V><E><G><T><S><N><P><N><L><Y><W><Y><R><Q><A><A><G><R><G><L><Q><L><L><F><Y><S><V><G><I><G><Q><I><S><S><E><V><P><Q><N><L><S><A><S><R><P><Q><D><R><Q><F><I><L><S><S><K><K><L><L><L><S><D><S><G><F><Y><L... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0K0K1B3 |
P01766 | HV313_HUMAN | Ig heavy chain V-III region BRO | Homo | <M><E><L><G><L><S><W><V><F><L><V><A><I><L><E><G><V><Q><C><E><V><Q><L><V><E><S><G><G><G><L><V><Q><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><S><S><Y><D><M><H><W><V><R><Q><A><T><G><K><G><L><E><W><V><S><A><I><G><T><A><G><D><P><Y><Y><P><G><S><V><K><G><R><F><T><I><S><R><E><N><A><K><N><S><L><Y><L><Q><M><N><S><L><R><A><G... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01766 |
Q15172 | 2A5A_HUMAN | PP2A B subunit isoform R5-alpha | Homo | <M><S><S><S><S><P><P><A><G><A><A><S><A><A><I><S><A><S><E><K><V><D><G><F><T><R><K><S><V><R><K><A><Q><R><Q><K><R><S><Q><G><S><S><Q><F><R><S><Q><G><S><Q><A><E><L><H><P><L><P><Q><L><K><D><A><T><S><N><E><Q><Q><E><L><F><C><Q><K><L><Q><Q><C><C><I><L><F><D><F><M><D><S><V><S><D><L><K><S><K><E><I><K><R><A><T><L><N><E><L><V><E><Y... | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.<BOP> | Q15172 |
P02808 | STAT_HUMAN | Statherin | Homo | <M><K><F><L><V><F><A><F><I><L><A><L><M><V><S><M><I><G><A><D><S><S><E><E><K><F><L><R><R><I><G><R><F><G><Y><G><Y><G><P><Y><Q><P><V><P><E><Q><P><L><Y><P><Q><P><Y><Q><P><Q><Y><Q><Q><Y><T><F> | Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface.<BOP> | P02808 |
P27144 | KAD4_HUMAN | GTP:AMP phosphotransferase AK4 | Homo | <M><A><S><K><L><L><R><A><V><I><L><G><P><P><G><S><G><K><G><T><V><C><Q><R><I><A><Q><N><F><G><L><Q><H><L><S><S><G><H><F><L><R><E><N><I><K><A><S><T><E><V><G><E><M><A><K><Q><Y><I><E><K><S><L><L><V><P><D><H><V><I><T><R><L><M><M><S><E><L><E><N><R><R><G><Q><H><W><L><L><D><G><F><P><R><T><L><G><Q><A><E><A><L><D><K><I><C><E><V><D... | Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates . Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor . Also displays broad nucleoside diphosphate kinase activity . ... | P27144 |
Q96CD0 | FBXL8_HUMAN | F-box protein FBL8 | Homo | <M><A><E><P><G><E><G><L><P><E><E><V><L><A><L><I><F><R><H><L><S><L><R><D><R><A><A><A><A><R><V><C><R><A><W><A><A><A><A><T><C><S><A><V><W><H><D><T><K><I><S><C><E><C><E><L><E><G><M><L><P><P><Y><L><S><A><C><L><D><H><I><H><N><L><R><L><E><F><E><P><S><R><K><P><S><R><R><A><A><I><E><L><L><M><V><L><A><G><R><A><P><G><L><R><G><L><R... | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<BOP> | Q96CD0 |
Q96KK4 | O10C1_HUMAN | Olfactory receptor 10C2 | Homo | <M><S><A><N><T><S><M><V><T><E><F><L><L><L><G><F><S><H><L><A><D><L><Q><G><L><L><F><S><V><F><L><T><I><Y><L><L><T><V><A><G><N><F><L><I><V><V><L><V><S><T><D><A><A><L><Q><S><P><M><Y><F><F><L><R><T><L><S><A><L><E><I><G><Y><T><S><V><T><V><P><L><L><L><H><H><L><L><T><G><R><R><H><I><S><R><S><G><C><A><L><Q><M><F><F><F><L><F><F><G... | Odorant receptor.<BOP> | Q96KK4 |
Q7Z340 | ZN551_HUMAN | Zinc finger protein KOX23 | Homo | <M><P><A><P><V><G><R><R><S><P><P><S><P><R><S><S><M><A><A><V><A><L><R><D><S><A><Q><G><M><T><F><E><D><V><A><I><Y><F><S><Q><E><E><W><E><L><L><D><E><S><Q><R><F><L><Y><C><D><V><M><L><E><N><F><A><H><V><T><S><L><G><Y><C><H><G><M><E><N><E><A><I><A><S><E><Q><S><V><S><I><Q><V><R><T><S><K><G><N><T><P><T><Q><K><T><H><L><S><E><I><K... | May be involved in transcriptional regulation.<BOP> | Q7Z340 |
Q8IYS4 | DAAF8_HUMAN | Dynein axonemal-associated protein 1 | Homo | <M><A><S><N><D><K><G><M><A><P><S><L><G><S><P><W><A><S><Q><M><G><P><W><D><A><I><L><K><A><V><K><D><Q><L><P><S><L><D><S><D><S><P><L><S><D><Y><G><E><E><E><L><F><I><F><Q><R><N><Q><T><S><L><I><P><D><L><S><E><E><L><A><E><D><P><A><D><G><D><K><S><R><A><W><V><A><A><A><E><E><S><L><P><E><P><V><L><V><P><A><E><L><A><T><E><P><G><C><R... | In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.<BOP> | Q8IYS4 |
O95125 | ZN202_HUMAN | Zinc finger protein with KRAB and SCAN domains 10 | Homo | <M><A><T><A><V><E><P><E><D><Q><D><L><W><E><E><E><G><I><L><M><V><K><L><E><D><D><F><T><C><R><P><E><S><V><L><Q><R><D><D><P><V><L><E><T><S><H><Q><N><F><R><R><F><R><Y><Q><E><A><A><S><P><R><E><A><L><I><R><L><R><E><L><C><H><Q><W><L><R><P><E><R><R><T><K><E><Q><I><L><E><L><L><V><L><E><Q><F><L><T><V><L><P><G><E><L><Q><S><W><V><R... | Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), ... | O95125 |
A0A1B0GX51 | TVB78_HUMAN | T cell receptor beta variable 7-8 | Homo | <M><G><T><R><L><L><C><W><V><V><L><G><F><L><G><T><D><H><T><G><A><G><V><S><Q><S><P><R><Y><K><V><A><K><R><G><Q><D><V><A><L><R><C><D><P><I><S><G><H><V><S><L><F><W><Y><Q><Q><A><L><G><Q><G><P><E><F><L><T><Y><F><Q><N><E><A><Q><L><D><K><S><G><L><P><S><D><R><F><F><A><E><R><P><E><G><S><V><S><T><L><K><I><Q><R><T><Q><Q><E><D><S><A... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A1B0GX51 |
Q9H5X1 | CIA2A_HUMAN | MIP18 family protein FAM96A | Homo | <M><Q><R><V><S><G><L><L><S><W><T><L><S><R><V><L><W><L><S><G><L><S><E><P><G><A><A><R><Q><P><R><I><M><E><E><K><A><L><E><V><Y><D><L><I><R><T><I><R><D><P><E><K><P><N><T><L><E><E><L><E><V><V><S><E><S><C><V><E><V><Q><E><I><N><E><E><E><Y><L><V><I><I><R><F><T><P><T><V><P><H><C><S><L><A><T><L><I><G><L><C><L><R><V><K><L><Q><R><C... | Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins . As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iro... | Q9H5X1 |
Q9UPT9 | UBP22_HUMAN | Ubiquitin-specific-processing protease 22 | Homo | <M><V><S><R><P><E><P><E><G><E><A><M><D><A><E><L><A><V><A><P><P><G><C><S><H><L><G><S><F><K><V><D><N><W><K><Q><N><L><R><A><I><Y><Q><C><F><V><W><S><G><T><A><E><A><R><K><R><K><A><K><S><C><I><C><H><V><C><G><V><H><L><N><R><L><H><S><C><L><Y><C><V><F><F><G><C><F><T><K><K><H><I><H><E><H><A><K><A><K><R><H><N><L><A><I><D><L><M><Y... | Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nu... | Q9UPT9 |
P28562 | DUS1_HUMAN | Protein-tyrosine phosphatase CL100 | Homo | <M><V><M><E><V><G><T><L><D><A><G><G><L><R><A><L><L><G><E><R><A><A><Q><C><L><L><L><D><C><R><S><F><F><A><F><N><A><G><H><I><A><G><S><V><N><V><R><F><S><T><I><V><R><R><R><A><K><G><A><M><G><L><E><H><I><V><P><N><A><E><L><R><G><R><L><L><A><G><A><Y><H><A><V><V><L><L><D><E><R><S><A><A><L><D><G><A><K><R><D><G><T><L><A><L><A><A><G... | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.<BOP> | P28562 |
O15091 | MRPP3_HUMAN | Protein only RNase P catalytic subunit | Homo | <M><T><F><Y><L><F><G><I><R><S><F><P><K><L><W><K><S><P><Y><L><G><L><G><P><G><H><S><Y><V><S><L><F><L><A><D><R><C><G><I><R><N><Q><Q><R><L><F><S><L><K><T><M><S><P><Q><N><T><K><A><T><N><L><I><A><K><A><R><Y><L><R><K><D><E><G><S><N><K><Q><V><Y><S><V><P><H><F><F><L><A><G><A><A><K><E><R><S><Q><M><N><S><Q><T><E><D><H><A><L><A><P... | Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends . The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends .<BOP> | O15091 |
P54792 | DVLP1_HUMAN | Segment polarity protein dishevelled homolog DVL-1-like | Homo | <M><A><E><T><K><I><I><Y><H><M><D><E><E><E><T><P><Y><L><V><K><L><P><V><A><P><E><R><V><T><L><A><D><F><K><N><V><L><S><N><R><P><V><H><A><Y><K><F><F><F><K><S><M><D><Q><D><F><G><V><V><K><E><E><I><F><D><D><N><A><K><L><P><C><F><N><G><R><V><V><S><W><L><V><L><V><E><G><A><H><S><D><A><G><S><Q><G><T><D><S><H><T><D><L><P><P><P><L><E... | May play a role in the signal transduction pathway mediated by multiple Wnt genes.<BOP> | P54792 |
P42898 | MTHR_HUMAN | Methylenetetrahydrofolate reductase | Homo | <M><V><N><E><A><R><G><N><S><S><L><N><P><C><L><E><G><S><A><S><S><G><S><E><S><S><K><D><S><S><R><C><S><T><P><G><L><D><P><E><R><H><E><R><L><R><E><K><M><R><R><R><L><E><S><G><D><K><W><F><S><L><E><F><F><P><P><R><T><A><E><G><A><V><N><L><I><S><R><F><D><R><M><A><A><G><G><P><L><Y><I><D><V><T><W><H><P><A><G><D><P><G><S><D><K><E><T... | Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine . Represents a key regulatory connection between the folate and methionine cycles (Probable).<BOP> | P42898 |
P43357 | MAGA3_HUMAN | MAGE-3 antigen | Homo | <M><P><L><E><Q><R><S><Q><H><C><K><P><E><E><G><L><E><A><R><G><E><A><L><G><L><V><G><A><Q><A><P><A><T><E><E><Q><E><A><A><S><S><S><S><T><L><V><E><V><T><L><G><E><V><P><A><A><E><S><P><D><P><P><Q><S><P><Q><G><A><S><S><L><P><T><T><M><N><Y><P><L><W><S><Q><S><Y><E><D><S><S><N><Q><E><E><E><G><P><S><T><F><P><D><L><E><S><E><F><Q><A... | Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a as repressor of autophagy . May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugat... | P43357 |
Q9BXJ7 | AMNLS_HUMAN | Soluble protein amnionless | Homo | <M><G><V><L><G><R><V><L><L><W><L><Q><L><C><A><L><T><Q><A><V><S><K><L><W><V><P><N><T><D><F><D><V><A><A><N><W><S><Q><N><R><T><P><C><A><G><G><A><V><E><F><P><A><D><K><M><V><S><V><L><V><Q><E><G><H><A><V><S><D><M><L><L><P><L><D><G><E><L><V><L><A><S><G><A><G><F><G><V><S><D><V><G><S><H><L><D><C><G><A><G><E><P><A><V><F><R><D><S... | Membrane-bound component of the endocytic receptor formed by AMN and CUBN . Required for normal CUBN glycosylation and trafficking to the cell surface . The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12 . Required for normal CUBN-mediated protein transport in the kidney (Probable).<... | Q9BXJ7 |
Q9H8M7 | MINY3_HUMAN | Protein CARP | Homo | <M><S><E><L><T><K><E><L><M><E><L><V><W><G><T><K><S><S><P><G><L><S><D><T><I><F><C><R><W><T><Q><G><F><V><F><S><E><S><E><G><S><A><L><E><Q><F><E><G><G><P><C><A><V><I><A><P><V><Q><A><F><L><L><K><K><L><L><F><S><S><E><K><S><S><W><R><D><C><S><E><E><E><Q><K><E><L><L><C><H><T><L><C><D><I><L><E><S><A><C><C><D><H><S><G><S><Y><C><L... | Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.<BOP> | Q9H8M7 |
Q5VY09 | IER5_HUMAN | Immediate early response gene 5 protein | Homo | <M><E><F><K><L><E><A><H><R><I><V><S><I><S><L><G><K><I><Y><N><S><R><V><Q><R><G><G><I><K><L><H><K><N><L><L><V><S><L><V><L><R><S><A><R><Q><V><Y><L><S><D><P><C><P><G><L><Y><L><A><G><P><A><G><T><P><A><P><P><P><Q><Q><Q><P><G><E><P><A><A><G><P><P><A><G><W><G><E><P><P><P><P><A><A><R><A><S><W><P><E><T><E><P><Q><P><E><R><S><S><V... | Plays a role as a transcription factor . Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner . Mediates negative transcriptional regulation of CDC25B expression . Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosom... | Q5VY09 |
Q8N0Y5 | OR8I2_HUMAN | Olfactory receptor OR11-170 | Homo | <M><A><G><N><N><F><T><E><V><T><V><F><I><L><S><G><F><A><N><H><P><E><L><Q><V><S><L><F><L><M><F><L><F><I><Y><L><F><T><V><L><G><N><L><G><L><I><T><L><I><R><M><D><S><Q><L><H><T><P><M><Y><F><F><L><S><N><L><A><F><I><D><I><F><Y><S><S><T><V><T><P><K><A><L><V><N><F><Q><S><N><R><R><S><I><S><F><V><G><C><F><V><Q><M><Y><F><F><V><G><L... | Odorant receptor.<BOP> | Q8N0Y5 |
Q86SF2 | GALT7_HUMAN | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7 | Homo | <M><R><L><K><I><G><F><I><L><R><S><L><L><V><V><G><S><F><L><G><L><V><V><L><W><S><S><L><T><P><R><P><D><D><P><S><P><L><S><R><M><R><E><D><R><D><V><N><D><P><M><P><N><R><G><G><N><G><L><A><P><G><E><D><R><F><K><P><V><V><P><W><P><H><V><E><G><V><E><V><D><L><E><S><I><R><R><I><N><K><A><K><N><E><Q><E><H><H><A><G><G><D><S><Q><K><D><I... | Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue... | Q86SF2 |
Q9NP61 | ARFG3_HUMAN | ADP-ribosylation factor GTPase-activating protein 3 | Homo | <M><G><D><P><S><K><Q><D><I><L><T><I><F><K><R><L><R><S><V><P><T><N><K><V><C><F><D><C><G><A><K><N><P><S><W><A><S><I><T><Y><G><V><F><L><C><I><D><C><S><G><S><H><R><S><L><G><V><H><L><S><F><I><R><S><T><E><L><D><S><N><W><S><W><F><Q><L><R><C><M><Q><V><G><G><N><A><S><A><S><S><F><F><H><Q><H><G><C><S><T><N><D><T><N><A><K><Y><N><S... | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.<BOP> | Q9NP61 |
P09093 | CEL3A_HUMAN | Protease E | Homo | <M><M><L><R><L><L><S><S><L><L><L><V><A><V><A><S><G><Y><G><P><P><S><S><H><S><S><S><R><V><V><H><G><E><D><A><V><P><Y><S><W><P><W><Q><V><S><L><Q><Y><E><K><S><G><S><F><Y><H><T><C><G><G><S><L><I><A><P><D><W><V><V><T><A><G><H><C><I><S><R><D><L><T><Y><Q><V><V><L><G><E><Y><N><L><A><V><K><E><G><P><E><Q><V><I><P><I><N><S><E><E><L... | Efficient protease with alanine specificity but only little elastolytic activity.<BOP> | P09093 |
Q9UNQ2 | DIM1_HUMAN | Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase | Homo | <M><P><K><V><K><S><G><A><I><G><R><R><R><G><R><Q><E><Q><R><R><E><L><K><S><A><G><G><L><M><F><N><T><G><I><G><Q><H><I><L><K><N><P><L><I><I><N><S><I><I><D><K><A><A><L><R><P><T><D><V><V><L><E><V><G><P><G><T><G><N><M><T><V><K><L><L><E><K><A><K><K><V><V><A><C><E><L><D><P><R><L><V><A><E><L><H><K><R><V><Q><G><T><P><V><A><S><K><L... | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity .<BOP> | Q9UNQ2 |
Q9NY93 | DDX56_HUMAN | DEAD box protein 56 | Homo | <M><E><D><S><E><A><L><G><F><E><H><M><G><L><D><P><R><L><L><Q><A><V><T><D><L><G><W><S><R><P><T><L><I><Q><E><K><A><I><P><L><A><L><E><G><K><D><L><L><A><R><A><R><T><G><S><G><K><T><A><A><Y><A><I><P><M><L><Q><L><L><L><H><R><K><A><T><G><P><V><V><E><Q><A><V><R><G><L><V><L><V><P><T><K><E><L><A><R><Q><A><Q><S><M><I><Q><Q><L><A><T... | May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity.<BOP> | Q9NY93 |
Q96BS2 | CHP3_HUMAN | Tescalcin | Homo | <M><G><A><A><H><S><A><S><E><E><V><R><E><L><E><G><K><T><G><F><S><S><D><Q><I><E><Q><L><H><R><R><F><K><Q><L><S><G><D><Q><P><T><I><R><K><E><N><F><N><N><V><P><D><L><E><L><N><P><I><R><S><K><I><V><R><A><F><F><D><N><R><N><L><R><K><G><P><S><G><L><A><D><E><I><N><F><E><D><F><L><T><I><M><S><Y><F><R><P><I><D><T><T><M><D><E><E><Q><V... | Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megak... | Q96BS2 |
Q9H2K0 | IF3M_HUMAN | Translation initiation factor IF-3, mitochondrial | Homo | <M><A><A><L><F><L><K><R><L><T><L><Q><T><V><K><S><E><N><S><C><I><R><C><F><G><K><H><I><L><Q><K><T><A><P><A><Q><L><S><P><I><A><S><A><P><R><L><S><F><L><I><H><A><K><A><F><S><T><A><E><D><T><Q><N><E><G><K><K><T><K><K><N><K><T><A><F><S><N><V><G><R><K><I><S><Q><R><V><I><H><L><F><D><E><K><G><N><D><L><G><N><M><H><R><A><N><V><I><R... | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.<BOP> | Q9H2K0 |
Q5D1E8 | ZC12A_HUMAN | Zinc finger CCCH domain-containing protein 12A | Homo | <M><S><G><P><C><G><E><K><P><V><L><E><A><S><P><T><M><S><L><W><E><F><E><D><S><H><S><R><Q><G><T><P><R><P><G><Q><E><L><A><A><E><E><A><S><A><L><E><L><Q><M><K><V><D><F><F><R><K><L><G><Y><S><S><T><E><I><H><S><V><L><Q><K><L><G><V><Q><A><D><T><N><T><V><L><G><E><L><V><K><H><G><T><A><T><E><R><E><R><Q><T><S><P><D><P><C><P><Q><L><P... | (Microbial infection) Exhibits antiviral activity against HIV-1 in lymphocytes by decreasing the abundance of HIV-1 viral RNA species.<BOP> | Q5D1E8 |
A0A0B4J1U4 | TRGV5_HUMAN | T cell receptor gamma variable 5 | Homo | <M><R><W><A><L><L><V><L><L><A><F><L><S><P><A><S><Q><K><S><S><N><L><E><G><G><T><K><S><V><T><R><P><T><R><S><S><A><E><I><T><C><D><L><T><V><I><N><A><F><Y><I><H><W><Y><L><H><Q><E><G><K><A><P><Q><R><L><L><Y><Y><D><V><S><N><S><K><D><V><L><E><S><G><L><S><P><G><K><Y><Y><T><H><T><P><R><R><W><S><W><I><L><I><L><R><N><L><I><E><N><D... | V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition . Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids present... | A0A0B4J1U4 |
Q96LB9 | PGRP3_HUMAN | Peptidoglycan recognition protein intermediate alpha | Homo | <M><G><T><L><P><W><L><L><A><F><F><I><L><G><L><Q><A><W><D><T><P><T><I><V><S><R><K><E><W><G><A><R><P><L><A><C><R><A><L><L><T><L><P><V><A><Y><I><I><T><D><Q><L><P><G><M><Q><C><Q><Q><Q><S><V><C><S><Q><M><L><R><G><L><Q><S><H><S><V><Y><T><I><G><W><C><D><V><A><Y><N><F><L><V><G><D><D><G><R><V><Y><E><G><V><G><W><N><I><Q><G><L><H... | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bact... | Q96LB9 |
Q03431 | PTH1R_HUMAN | Parathyroid hormone 1 receptor | Homo | <M><G><T><A><R><I><A><P><G><L><A><L><L><L><C><C><P><V><L><S><S><A><Y><A><L><V><D><A><D><D><V><M><T><K><E><E><Q><I><F><L><L><H><R><A><Q><A><Q><C><E><K><R><L><K><E><V><L><Q><R><P><A><S><I><M><E><S><D><K><G><W><T><S><A><S><T><S><G><K><P><R><K><D><K><A><S><G><K><L><Y><P><E><S><E><E><D><K><E><A><P><T><G><S><R><Y><R><G><R><P... | Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.<BOP> | Q03431 |
Q7L945 | ZN627_HUMAN | Zinc finger protein 627 | Homo | <M><D><S><V><A><F><E><D><V><A><V><N><F><T><L><E><E><W><A><L><L><D><P><S><Q><K><N><L><Y><R><D><V><M><R><E><T><F><R><N><L><A><S><V><G><K><Q><W><E><D><Q><N><I><E><D><P><F><K><I><P><R><R><N><I><S><H><I><P><E><R><L><C><E><S><K><E><G><G><Q><G><E><E><T><F><S><Q><I><P><D><G><I><L><N><K><K><T><P><G><V><K><P><C><E><S><S><V><C><G... | May be involved in transcriptional regulation.<BOP> | Q7L945 |
A6NIM6 | S15A5_HUMAN | Solute carrier family 15 member 5 | Homo | <M><S><V><T><G><F><T><I><T><D><E><K><V><H><L><Y><H><S><I><E><K><E><K><T><V><R><H><I><G><D><L><C><S><S><H><S><V><K><K><I><Q><V><G><I><C><L><L><L><V><E><L><C><E><R><F><T><F><F><E><V><V><C><N><M><I><P><F><C><T><I><K><L><G><Y><H><N><C><Q><A><A><I><L><N><L><C><F><I><G><T><S><I><L><T><P><V><F><V><R><W><L><T><D><V><Y><L><G><R... | Proton oligopeptide cotransporter.<BOP> | A6NIM6 |
O14737 | PDCD5_HUMAN | TF-1 cell apoptosis-related protein 19 | Homo | <M><A><D><E><E><L><E><A><L><R><R><Q><R><L><A><E><L><Q><A><K><H><G><D><P><G><D><A><A><Q><Q><E><A><K><H><R><E><A><E><M><R><N><S><I><L><A><Q><V><L><D><Q><S><A><R><A><R><L><S><N><L><A><L><V><K><P><E><K><T><K><A><V><E><N><Y><L><I><Q><M><A><R><Y><G><Q><L><S><E><K><V><S><E><Q><G><L><I><E><I><L><K><K><V><S><Q><Q><T><E><K><T><T... | May function in the process of apoptosis.<BOP> | O14737 |
P40937 | RFC5_HUMAN | Replication factor C 36 kDa subunit | Homo | <M><E><T><S><A><L><K><Q><Q><E><Q><P><A><A><T><K><I><R><N><L><P><W><V><E><K><Y><R><P><Q><T><L><N><D><L><I><S><H><Q><D><I><L><S><T><I><Q><K><F><I><N><E><D><R><L><P><H><L><L><L><Y><G><P><P><G><T><G><K><T><S><T><I><L><A><C><A><K><Q><L><Y><K><D><K><E><F><G><S><M><V><L><E><L><N><A><S><D><D><R><G><I><D><I><I><R><G><P><I><L><S... | The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.<BOP> | P40937 |
O75474 | FRAT2_HUMAN | Frequently rearranged in advanced T-cell lymphomas 2 | Homo | <M><P><C><R><R><E><E><E><E><E><A><G><E><E><A><E><G><E><E><E><E><D><D><S><F><L><L><L><Q><Q><S><V><T><L><G><S><S><G><E><V><D><R><L><V><A><Q><I><G><E><T><L><Q><L><D><A><A><Q><D><S><P><A><S><P><C><A><P><P><G><V><P><L><R><A><P><G><P><L><A><A><A><V><P><A><D><K><A><R><P><P><A><V><P><L><L><L><P><P><A><S><A><E><T><V><G><P><A><P... | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.<BOP> | O75474 |
P23919 | KTHY_HUMAN | dTMP kinase | Homo | <M><A><A><R><R><G><A><L><I><V><L><E><G><V><D><R><A><G><K><S><T><Q><S><R><K><L><V><E><A><L><C><A><A><G><H><R><A><E><L><L><R><F><P><E><R><S><T><E><I><G><K><L><L><S><S><Y><L><Q><K><K><S><D><V><E><D><H><S><V><H><L><L><F><S><A><N><R><W><E><Q><V><P><L><I><K><E><K><L><S><Q><G><V><T><L><V><V><D><R><Y><A><F><S><G><V><A><F><T><G... | Catalyzes the phosphorylation of thymidine monophosphate (dTMP) to thymidine diphosphate (dTDP), the immediate precursor for the DNA building block dTTP, with ATP as the preferred phosphoryl donor in the presence of Mg(2+).<BOP> | P23919 |
Q8IV04 | TB10C_HUMAN | TBC1 domain family member 10C | Homo | <M><A><Q><A><L><G><E><D><L><V><Q><P><P><E><L><Q><D><D><S><S><S><L><G><S><D><S><E><L><S><G><P><G><P><Y><R><Q><A><D><R><Y><G><F><I><G><G><S><S><A><E><P><G><P><G><H><P><P><A><D><L><I><R><Q><R><E><M><K><W><V><E><M><T><S><H><W><E><K><T><M><S><R><R><Y><K><K><V><K><M><Q><C><R><K><G><I><P><S><A><L><R><A><R><C><W><P><L><L><C><G... | Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.<BOP> | Q8IV04 |
Q8NDQ6 | ZN540_HUMAN | Zinc finger protein 540 | Homo | <M><A><H><A><L><V><T><F><R><D><V><A><I><D><F><S><Q><K><E><W><E><C><L><D><T><T><Q><R><K><L><Y><R><D><V><M><L><E><N><Y><N><N><L><V><S><L><G><Y><S><G><S><K><P><D><V><I><T><L><L><E><Q><G><K><E><P><C><V><V><A><R><D><V><T><G><R><Q><C><P><G><L><L><S><R><H><K><T><K><K><L><S><S><E><K><D><I><H><E><I><S><L><S><K><E><S><I><I><E><K... | May act as a transcriptional repressor.<BOP> | Q8NDQ6 |
Q52LD8 | RFTN2_HUMAN | Raft-linking protein 2 | Homo | <M><G><C><G><L><R><K><L><E><D><P><D><D><S><S><P><G><K><I><F><S><T><L><K><R><P><Q><V><E><T><K><T><E><F><A><Y><E><Y><V><L><L><D><F><T><L><Q><A><S><S><N><P><E><V><I><K><I><N><S><I><L><D><I><V><T><K><V><E><N><Y><Y><L><K><G><Y><I><V><G><A><I><H><P><V><I><Q><P><V><G><Q><R><K><H><L><P><A><S><Y><L><Y><R><V><V><L><L><R><L><K><L... | Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.<BOP> | Q52LD8 |
P62191 | PRS4_HUMAN | Proteasome 26S subunit ATPase 1 | Homo | <M><G><Q><S><Q><S><G><G><H><G><P><G><G><G><K><K><D><D><K><D><K><K><K><K><Y><E><P><P><V><P><T><R><V><G><K><K><K><K><K><T><K><G><P><D><A><A><S><K><L><P><L><V><T><P><H><T><Q><C><R><L><K><L><L><K><L><E><R><I><K><D><Y><L><L><M><E><E><E><F><I><R><N><Q><E><Q><M><K><P><L><E><E><K><Q><E><E><E><R><S><K><V><D><D><L><R><G><T><P><M... | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions ... | P62191 |
P23760 | PAX3_HUMAN | HuP2 | Homo | <M><T><T><L><A><G><A><V><P><R><M><M><R><P><G><P><G><Q><N><Y><P><R><S><G><F><P><L><E><V><S><T><P><L><G><Q><G><R><V><N><Q><L><G><G><V><F><I><N><G><R><P><L><P><N><H><I><R><H><K><I><V><E><M><A><H><H><G><I><R><P><C><V><I><S><R><Q><L><R><V><S><H><G><C><V><S><K><I><L><C><R><Y><Q><E><T><G><S><I><R><P><G><A><I><G><G><S><K><P><K... | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 .<BOP> | P23760 |
Q9HBU9 | POPD2_HUMAN | Popeye domain-containing protein 2 | Homo | <M><S><A><N><S><S><R><V><G><Q><L><L><L><Q><G><S><A><C><I><R><W><K><Q><D><V><E><G><A><V><Y><H><L><A><N><C><L><L><L><L><G><F><M><G><G><S><G><V><Y><G><C><F><Y><L><F><G><F><L><S><A><G><Y><L><C><C><V><L><W><G><W><F><S><A><C><G><L><D><I><V><L><W><S><F><L><L><A><V><V><C><L><L><Q><L><A><H><L><V><Y><R><L><R><E><D><T><L><P><E><E... | Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.<BOP> | Q9HBU9 |
Q96K37 | S35E1_HUMAN | Solute carrier family 35 member E1 | Homo | <M><A><A><A><A><V><G><A><G><H><G><A><G><G><P><G><A><A><S><S><S><G><G><A><R><E><G><A><R><V><A><A><L><C><L><L><W><Y><A><L><S><A><G><G><N><V><V><N><K><V><I><L><S><A><F><P><F><P><V><T><V><S><L><C><H><I><L><A><L><C><A><G><L><P><P><L><L><R><A><W><R><V><P><P><A><P><P><V><S><G><P><G><P><S><P><H><P><S><S><G><P><L><L><P><P><R><F... | Putative transporter.<BOP> | Q96K37 |
Q13530 | SERC3_HUMAN | Tumor differentially expressed protein 1 | Homo | <M><G><A><V><L><G><V><F><S><L><A><S><W><V><P><C><L><C><S><G><A><S><C><L><L><C><S><C><C><P><N><S><K><N><S><T><V><T><R><L><I><Y><A><F><I><L><L><L><S><T><V><V><S><Y><I><M><Q><R><K><E><M><E><T><Y><L><K><K><I><P><G><F><C><E><G><G><F><K><I><H><E><A><D><I><N><A><D><K><D><C><D><V><L><V><G><Y><K><A><V><Y><R><I><S><F><A><M><A><I... | Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm .<BOP> | Q13530 |
P15515 | HIS1_HUMAN | Histatin-2 | Homo | <M><K><F><F><V><F><A><L><V><L><A><L><M><I><S><M><I><S><A><D><S><H><E><K><R><H><H><G><Y><R><R><K><F><H><E><K><H><H><S><H><R><E><F><P><F><Y><G><D><Y><G><S><N><Y><L><Y><D><N> | Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.<BOP> | P15515 |
Q9GZY8 | MFF_HUMAN | Mitochondrial fission factor | Homo | <M><S><K><G><T><S><S><D><T><S><L><G><R><V><S><R><A><A><F><P><S><P><T><A><A><E><M><A><E><I><S><R><I><Q><Y><E><M><E><Y><T><E><G><I><S><Q><R><M><R><V><P><E><K><L><K><V><A><P><P><N><A><D><L><E><Q><G><F><Q><E><G><V><P><N><A><S><V><I><M><Q><V><P><E><R><I><V><V><A><G><N><N><E><D><V><S><F><S><R><P><A><D><L><D><L><I><Q><S><T><P... | Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.<BOP> | Q9GZY8 |
Q96KJ9 | COX42_HUMAN | Cytochrome c oxidase subunit IV isoform 2 | Homo | <M><L><P><R><A><A><W><S><L><V><L><R><K><G><G><G><G><R><R><G><M><H><S><S><E><G><T><T><R><G><G><G><K><M><S><P><Y><T><N><C><Y><A><Q><R><Y><Y><P><M><P><E><E><P><F><C><T><E><L><N><A><E><E><Q><A><L><K><E><K><E><K><G><S><W><T><Q><L><T><H><A><E><K><V><A><L><Y><R><L><Q><F><N><E><T><F><A><E><M><N><R><R><S><N><E><W><K><T><V><M><G... | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | Q96KJ9 |
P55036 | PSMD4_HUMAN | Multiubiquitin chain-binding protein | Homo | <M><V><L><E><S><T><M><V><C><V><D><N><S><E><Y><M><R><N><G><D><F><L><P><T><R><L><Q><A><Q><Q><D><A><V><N><I><V><C><H><S><K><T><R><S><N><P><E><N><N><V><G><L><I><T><L><A><N><D><C><E><V><L><T><T><L><T><P><D><T><G><R><I><L><S><K><L><H><T><V><Q><P><K><G><K><I><T><F><C><T><G><I><R><V><A><H><L><A><L><K><H><R><Q><G><K><N><H><K><M... | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions ... | P55036 |
Q12887 | COX10_HUMAN | Heme O synthase | Homo | <M><A><A><S><P><H><T><L><S><S><R><L><L><T><G><C><V><G><G><S><V><W><Y><L><E><R><R><T><I><Q><D><S><P><H><K><F><L><H><L><L><R><N><V><N><K><Q><W><I><T><F><Q><H><F><S><F><L><K><R><M><Y><V><T><Q><L><N><R><S><H><N><Q><Q><V><R><P><K><P><E><P><V><A><S><P><F><L><E><K><T><S><S><G><Q><A><K><A><E><I><Y><E><M><R><P><L><S><P><P><S><L... | Converts protoheme IX and farnesyl diphosphate to heme O.<BOP> | Q12887 |
Q96T66 | NMNA3_HUMAN | Pyridine nucleotide adenylyltransferase 3 | Homo | <M><K><S><R><I><P><V><V><L><L><A><C><G><S><F><N><P><I><T><N><M><H><L><R><M><F><E><V><A><R><D><H><L><H><Q><T><G><M><Y><Q><V><I><Q><G><I><I><S><P><V><N><D><T><Y><G><K><K><D><L><A><A><S><H><H><R><V><A><M><A><R><L><A><L><Q><T><S><D><W><I><R><V><D><P><W><E><S><E><Q><A><Q><W><M><E><T><V><K><V><L><R><H><H><H><S><K><L><L><R><S... | Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse... | Q96T66 |
P35527 | K1C9_HUMAN | Keratin-9 | Homo | <M><S><C><R><Q><F><S><S><S><Y><L><S><R><S><G><G><G><G><G><G><G><L><G><S><G><G><S><I><R><S><S><Y><S><R><F><S><S><S><G><G><G><G><G><G><G><R><F><S><S><S><S><G><Y><G><G><G><S><S><R><V><C><G><R><G><G><G><G><S><F><G><Y><S><Y><G><G><G><S><G><G><G><F><S><A><S><S><L><G><G><G><F><G><G><G><S><R><G><F><G><G><A><S><G><G><G><Y><S><S... | May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.<BOP> | P35527 |
Q8NEV9 | IL27A_HUMAN | p28 | Homo | <M><G><Q><T><A><G><D><L><G><W><R><L><S><L><L><L><L><P><L><L><L><V><Q><A><G><V><W><G><F><P><R><P><P><G><R><P><Q><L><S><L><Q><E><L><R><R><E><F><T><V><S><L><H><L><A><R><K><L><L><S><E><V><R><G><Q><A><H><R><F><A><E><S><H><L><P><G><V><N><L><Y><L><L><P><L><G><E><Q><L><P><D><V><S><L><T><F><Q><A><W><R><R><L><S><D><P><E><R><L><C... | Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that... | Q8NEV9 |
Q6NUK1 | SCMC1_HUMAN | Solute carrier family 25 member 24 | Homo | <M><L><R><W><L><R><D><F><V><L><P><T><A><A><C><Q><D><A><E><Q><P><T><R><Y><E><T><L><F><Q><A><L><D><R><N><G><D><G><V><V><D><I><G><E><L><Q><E><G><L><R><N><L><G><I><P><L><G><Q><D><A><E><E><K><I><F><T><T><G><D><V><N><K><D><G><K><L><D><F><E><E><F><M><K><Y><L><K><D><H><E><K><K><M><K><L><A><F><K><S><L><D><K><N><N><D><G><K><I><E... | Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is ... | Q6NUK1 |
Q96LR9 | APLD1_HUMAN | Vascular early response gene protein | Homo | <M><F><R><A><P><C><H><R><L><R><A><R><G><T><R><K><A><R><A><G><A><W><R><G><C><T><F><P><C><L><G><K><G><M><E><R><P><A><A><R><E><P><H><G><P><D><A><L><R><R><F><Q><G><L><L><L><D><R><R><G><R><L><H><G><Q><V><L><R><L><R><E><V><A><R><R><L><E><R><L><R><R><R><S><L><V><A><N><V><A><G><S><S><L><S><A><T><G><A><L><A><A><I><V><G><L><S><L... | May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability.<BOP> | Q96LR9 |
O95936 | EOMES_HUMAN | T-box brain protein 2 | Homo | <M><Q><L><G><E><Q><L><L><V><S><S><V><N><L><P><G><A><H><F><Y><P><L><E><S><A><R><G><G><S><G><G><S><A><G><H><L><P><S><A><A><P><S><P><Q><K><L><D><L><D><K><A><S><K><K><F><S><G><S><L><S><C><E><A><V><S><G><E><P><A><A><A><S><A><G><A><P><A><A><M><L><S><D><T><D><A><G><D><A><F><A><S><A><A><A><V><A><K><P><G><P><P><D><G><R><K><G><S... | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the in... | O95936 |
P24530 | EDNRB_HUMAN | Endothelin receptor non-selective type | Homo | <M><Q><P><P><P><S><L><C><G><R><A><L><V><A><L><V><L><A><C><G><L><S><R><I><W><G><E><E><R><G><F><P><P><D><R><A><T><P><L><L><Q><T><A><E><I><M><T><P><P><T><K><T><L><W><P><K><G><S><N><A><S><L><A><R><S><L><A><P><A><E><V><P><K><G><D><R><T><A><G><S><P><P><R><T><I><S><P><P><P><C><Q><G><P><I><E><I><K><E><T><F><K><Y><I><N><T><V><V... | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.<BOP> | P24530 |
A6NJG6 | ARGFX_HUMAN | Arginine-fifty homeobox | Homo | <M><R><N><R><M><A><P><E><N><P><Q><P><D><P><F><I><N><R><N><Y><S><N><M><K><V><I><P><P><Q><D><P><A><S><P><S><F><T><L><L><S><K><L><E><C><S><G><T><V><S><A><Y><C><S><L><N><L><P><G><S><T><D><P><P><T><S><A><S><R><V><A><A><T><T><A><I><R><R><R><H><K><E><R><T><S><F><T><H><Q><Q><Y><E><E><L><E><A><L><F><S><Q><T><M><F><P><D><R><N><L... | Transcription factor that acts as activator.<BOP> | A6NJG6 |
Q8NH90 | O5AK2_HUMAN | Olfactory receptor 5AK2 | Homo | <M><T><L><G><N><S><T><E><V><T><E><F><Y><L><L><G><F><G><A><Q><H><E><F><W><C><I><L><F><I><V><F><L><L><I><Y><V><T><S><I><M><G><N><S><G><I><I><L><L><I><N><T><D><S><R><F><Q><T><L><T><Y><F><F><L><Q><H><L><A><F><V><D><I><C><Y><T><S><A><I><T><P><K><M><L><Q><S><F><T><E><E><K><N><L><M><L><F><Q><G><C><V><I><Q><F><L><V><Y><A><T><F... | Odorant receptor.<BOP> | Q8NH90 |
Q9BQA5 | HINFP_HUMAN | Methyl-CpG-binding protein 2-interacting zinc finger protein | Homo | <M><P><P><P><G><K><V><P><R><K><E><N><L><W><L><Q><C><E><W><G><S><C><S><F><V><C><S><T><M><E><K><F><F><E><H><V><T><Q><H><L><Q><Q><H><L><H><G><S><G><E><E><E><E><E><E><E><E><D><D><P><L><E><E><E><F><S><C><L><W><Q><E><C><G><F><C><S><L><D><S><S><A><D><L><I><R><H><V><Y><F><H><C><Y><H><T><K><L><K><Q><W><G><L><Q><A><L><Q><S><Q><A... | Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by ass... | Q9BQA5 |
Q99941 | ATF6B_HUMAN | Processed cyclic AMP-dependent transcription factor ATF-6 beta | Homo | <M><A><E><L><M><L><L><S><E><I><A><D><P><T><R><F><F><T><D><N><L><L><S><P><E><D><W><G><L><Q><N><S><T><L><Y><S><G><L><D><E><V><A><E><E><Q><T><Q><L><F><R><C><P><E><Q><D><V><P><F><D><G><S><S><L><D><V><G><M><D><V><S><P><S><E><P><P><W><E><L><L><P><I><F><P><D><L><Q><V><K><S><E><P><S><S><P><C><S><S><S><S><L><S><S><E><S><S><R><L... | Transcription factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress . Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE .<BOP> | Q99941 |
Q99706 | KI2L4_HUMAN | MHC class I NK cell receptor KIR103AS | Homo | <M><S><M><S><P><T><V><I><I><L><A><C><L><G><F><F><L><D><Q><S><V><W><A><H><V><G><G><Q><D><K><P><F><C><S><A><W><P><S><A><V><V><P><Q><G><G><H><V><T><L><R><C><H><Y><R><R><G><F><N><I><F><T><L><Y><K><K><D><G><V><P><V><P><E><L><Y><N><R><I><F><W><N><S><F><L><I><S><P><V><T><P><A><H><A><G><T><Y><R><C><R><G><F><H><P><H><S><P><T><E... | Receptor for non-classical major histocompatibility class Ib HLA-G molecules. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M). In decidual NK cells, binds peptide-bound HLA-G-B2M complex and triggers NK cell senescence-associated secretory phenotype as a mo... | Q99706 |
Q9NYW8 | RBAK_HUMAN | Zinc finger protein 769 | Homo | <M><N><T><L><Q><G><P><V><S><F><K><D><V><A><V><D><F><T><Q><E><E><W><Q><Q><L><D><P><D><E><K><I><T><Y><R><D><V><M><L><E><N><Y><S><H><L><V><S><V><G><Y><D><T><T><K><P><N><V><I><I><K><L><E><Q><G><E><E><P><W><I><M><G><G><E><F><P><C><Q><H><S><P><E><A><W><R><V><D><D><L><I><E><R><I><Q><E><N><E><D><K><H><S><R><Q><A><A><C><I><N><S... | May repress E2F-dependent transcription. May promote AR-dependent transcription.<BOP> | Q9NYW8 |
K9M1U5 | IFNL4_HUMAN | Interferon lambda-4 | Homo | <M><R><P><S><V><W><A><A><V><A><A><G><L><W><V><L><C><T><V><I><A><A><A><P><R><R><C><L><L><S><H><Y><R><S><L><E><P><R><T><L><A><A><A><K><A><L><R><D><R><Y><E><E><E><A><L><S><W><G><Q><R><N><C><S><F><R><P><R><R><D><P><P><R><P><S><S><C><A><R><L><R><H><V><A><R><G><I><A><D><A><Q><A><V><L><S><G><L><H><R><S><E><L><L><P><G><A><G><P... | Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes.<BOP> | K9M1U5 |
P05108 | CP11A_HUMAN | Cytochrome P450(scc) | Homo | <M><L><A><K><G><L><P><P><R><S><V><L><V><K><G><C><Q><T><F><L><S><A><P><R><E><G><L><G><R><L><R><V><P><T><G><E><G><A><G><I><S><T><R><S><P><R><P><F><N><E><I><P><S><P><G><D><N><G><W><L><N><L><Y><H><F><W><R><E><T><G><T><H><K><V><H><L><H><H><V><Q><N><F><Q><K><Y><G><P><I><Y><R><E><K><L><G><N><V><E><S><V><Y><V><I><D><P><E><D><V... | A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones . Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxy... | P05108 |
Q8N4W6 | DJC22_HUMAN | DnaJ homolog subfamily C member 22 | Homo | <M><A><K><G><L><L><V><T><Y><A><L><W><A><V><G><G><P><A><G><L><H><H><L><Y><L><G><R><D><S><H><A><L><L><W><M><L><T><L><G><G><G><G><L><G><W><L><W><E><F><W><K><L><P><S><F><V><A><Q><A><N><R><A><Q><G><Q><R><Q><S><P><R><G><V><T><P><P><L><S><P><I><R><F><A><A><Q><V><I><V><G><I><Y><F><G><L><V><A><L><I><S><L><S><S><M><V><N><F><Y><I... | May function as a co-chaperone.<BOP> | Q8N4W6 |
A0A0A6YYK1 | TVA81_HUMAN | T cell receptor alpha variable 8-1 | Homo | <M><L><L><L><L><I><P><V><L><G><M><I><F><A><L><R><D><A><R><A><Q><S><V><S><Q><H><N><H><H><V><I><L><S><E><A><A><S><L><E><L><G><C><N><Y><S><Y><G><G><T><V><N><L><F><W><Y><V><Q><Y><P><G><Q><H><L><Q><L><L><L><K><Y><F><S><G><D><P><L><V><K><G><I><K><G><F><E><A><E><F><I><K><S><K><F><S><F><N><L><R><K><P><S><V><Q><W><S><D><T><A><E... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A0A6YYK1 |
Q7L8L6 | FAKD5_HUMAN | FAST kinase domain-containing protein 5, mitochondrial | Homo | <M><A><A><T><L><K><S><L><K><L><V><R><Y><R><A><F><C><S><P><S><A><F><G><A><V><R><S><V><S><Y><W><N><V><S><S><T><Q><H><G><G><Q><D><P><P><E><H><I><S><L><C><H><S><A><K><K><V><K><N><I><C><S><T><F><S><S><R><R><I><L><T><T><S><S><A><H><P><G><L><E><F><S><K><T><S><S><S><K><A><S><T><L><Q><L><G><S><P><R><A><T><G><V><D><E><E><D><V><E... | Plays an important role in the processing of non-canonical mitochondrial mRNA precursors .<BOP> | Q7L8L6 |
P60410 | KR108_HUMAN | Keratin-associated protein 18.8 | Homo | <M><A><D><A><C><C><T><R><T><Y><V><I><A><A><S><T><M><S><V><C><S><S><D><V><G><H><V><S><R><V><S><S><P><S><T><C><T><G><S><S><W><Q><V><D><N><C><Q><E><S><C><C><E><P><R><S><C><A><S><S><C><C><T><P><S><C><C><A><P><A><P><C><L><A><L><V><C><A><P><V><S><C><E><P><S><P><C><Q><S><G><C><T><D><S><C><T><P><S><C><C><Q><Q><S><S><C><Q><P><A... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60410 |
P13584 | CP4B1_HUMAN | Cytochrome P450-HP | Homo | <M><V><P><S><F><L><S><L><S><F><S><S><L><G><L><W><A><S><G><L><I><L><V><L><G><F><L><K><L><I><H><L><L><L><R><R><Q><T><L><A><K><A><M><D><K><F><P><G><P><P><T><H><W><L><F><G><H><A><L><E><I><Q><E><T><G><S><L><D><K><V><V><S><W><A><H><Q><F><P><Y><A><H><P><L><W><F><G><Q><F><I><G><F><L><N><I><Y><E><P><D><Y><A><K><A><V><Y><S><R><G... | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.<BOP> | P13584 |
Q8WZ92 | OR5P2_HUMAN | Olfactory receptor-like protein JCG3 | Homo | <M><N><S><L><K><D><G><N><H><T><A><L><T><G><F><I><L><L><G><L><T><D><D><P><I><L><R><V><I><L><F><M><I><I><L><S><G><N><L><S><I><I><I><L><I><R><I><S><S><Q><L><H><H><P><M><Y><F><F><L><S><H><L><A><F><A><D><M><A><Y><S><S><S><V><T><P><N><M><L><V><N><F><L><V><E><R><N><T><V><S><Y><L><G><C><A><I><Q><L><G><S><A><A><F><F><A><T><V><E... | Odorant receptor (Potential). May be involved in taste perception.<BOP> | Q8WZ92 |
P12724 | ECP_HUMAN | Ribonuclease 3 | Homo | <M><V><P><K><L><F><T><S><Q><I><C><L><L><L><L><L><G><L><M><G><V><E><G><S><L><H><A><R><P><P><Q><F><T><R><A><Q><W><F><A><I><Q><H><I><S><L><N><P><P><R><C><T><I><A><M><R><A><I><N><N><Y><R><W><R><C><K><N><Q><N><T><F><L><R><T><T><F><A><N><V><V><N><V><C><G><N><Q><S><I><R><C><P><H><N><R><T><L><N><N><C><H><R><S><R><F><R><V><P><L... | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration... | P12724 |
Q02318 | CP27A_HUMAN | Vitamin D(3) 25-hydroxylase | Homo | <M><A><A><L><G><C><A><R><L><R><W><A><L><R><G><A><G><R><G><L><C><P><H><G><A><R><A><K><A><A><I><P><A><A><L><P><S><D><K><A><T><G><A><P><G><A><G><P><G><V><R><R><R><Q><R><S><L><E><E><I><P><R><L><G><Q><L><R><F><F><F><Q><L><F><V><Q><G><Y><A><L><Q><L><H><Q><L><Q><V><L><Y><K><A><K><Y><G><P><M><W><M><S><Y><L><G><P><Q><M><H><V><N... | Cytochrome P450 monooxygenase that catalyzes regio- and stereospecific hydroxylation of cholesterol and its derivatives. Hydroxylates (with R stereochemistry) the terminal methyl group of cholesterol side-chain in a three step reaction to yield at first a C26 alcohol, then a C26 aldehyde and finally a C26 acid . Regula... | Q02318 |
Q13938 | CAYP1_HUMAN | Calcyphosine | Homo | <M><Q><C><H><R><D><L><A><L><S><Q><A><L><W><G><W><Q><L><S><K><Q><S><G><W><A><H><P><S><L><P><H><S><P><L><P><S><T><V><H><S><C><S><W><A><P><P><H><L><Q><R><H><L><P><L><A><T><V><S><P><G><T><T><Q><L><T><Q><G><P><A><G><R><T><L><G><Q><T><Q><A><S><C><P><E><P><R><P><S><M><D><A><V><D><A><T><M><E><K><L><R><A><Q><C><L><S><R><G><A><S... | Calcium-binding protein. May play a role in cellular signaling events (Potential).<BOP> | Q13938 |
Q9H9L3 | I20L2_HUMAN | Interferon-stimulated 20 kDa exonuclease-like 2 | Homo | <M><S><T><L><L><L><N><L><D><F><G><E><P><P><P><K><K><A><L><E><G><N><A><K><H><R><N><F><V><K><K><R><R><L><L><E><R><R><G><F><L><S><K><K><N><Q><P><P><S><K><A><P><K><L><H><S><E><P><S><K><K><G><E><T><P><T><V><D><G><T><W><K><T><P><S><F><P><K><K><K><T><A><A><S><S><N><G><S><G><Q><P><L><D><K><K><A><A><V><S><W><L><T><P><A><P><S><K... | 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA. Displays a strong specificity for a 3'-end containing a free hydroxyl group.<BOP> | Q9H9L3 |
B1APH4 | ZN487_HUMAN | KRAB domain only protein 1 | Homo | <M><A><S><R><P><R><P><R><T><P><S><R><G><P><S><D><L><R><F><R><G><E><A><G><L><R><R><V><F><L><K><K><A><G><G><S><V><S><F><S><D><V><A><V><G><F><T><Q><E><E><W><Q><H><L><D><S><A><Q><R><T><P><Y><R><D><M><M><L><E><N><Y><S><L><L><L><S><V><G><Y><C><I><T><K><P><E><V><V><C><K><L><E><H><G><Q><V><L><W><I><L><E><E><E><S><P><S><Q><S><H... | May be involved in transcriptional regulation.<BOP> | B1APH4 |
Q00059 | TFAM_HUMAN | Transcription factor 6-like 2 | Homo | <M><A><F><L><R><S><M><W><G><V><L><S><A><L><G><R><S><G><A><E><L><C><T><G><C><G><S><R><L><R><S><P><F><S><F><V><Y><L><P><R><W><F><S><S><V><L><A><S><C><P><K><K><P><V><S><S><Y><L><R><F><S><K><E><Q><L><P><I><F><K><A><Q><N><P><D><A><K><T><T><E><L><I><R><R><I><A><Q><R><W><R><E><L><P><D><S><K><K><K><I><Y><Q><D><A><Y><R><A><E><W... | Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation . Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA . In this complex, TFAM recruits POLRMT to... | Q00059 |
O60256 | KPRB_HUMAN | 41 kDa phosphoribosypyrophosphate synthetase-associated protein | Homo | <M><F><C><V><T><P><P><E><L><E><T><K><M><N><I><T><K><G><G><L><V><L><F><S><A><N><S><N><S><S><C><M><E><L><S><K><K><I><A><E><R><L><G><V><E><M><G><K><V><Q><V><Y><Q><E><P><N><R><E><T><R><V><Q><I><Q><E><S><V><R><G><K><D><V><F><I><I><Q><T><V><S><K><D><V><N><T><T><I><M><E><L><L><I><M><V><Y><A><C><K><T><S><C><A><K><S><I><I><G><V... | Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.<BOP> | O60256 |
Q02221 | CX6A2_HUMAN | Cytochrome c oxidase subunit VIA-muscle | Homo | <M><A><L><P><L><R><P><L><T><R><G><L><A><S><A><A><K><G><G><H><G><G><A><G><A><R><T><W><R><L><L><T><F><V><L><A><L><P><S><V><A><L><C><T><F><N><S><Y><L><H><S><G><H><R><P><R><P><E><F><R><P><Y><Q><H><L><R><I><R><T><K><P><Y><P><W><G><D><G><N><H><T><L><F><H><N><S><H><V><N><P><L><P><T><G><Y><E><H><P> | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | Q02221 |
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