accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q01543 | FLI1_HUMAN | Transcription factor ERGB | Homo | <M><D><G><T><I><K><E><A><L><S><V><V><S><D><D><Q><S><L><F><D><S><A><Y><G><A><A><A><H><L><P><K><A><D><M><T><A><S><G><S><P><D><Y><G><Q><P><H><K><I><N><P><L><P><P><Q><Q><E><W><I><N><Q><P><V><R><V><N><V><K><R><E><Y><D><H><M><N><G><S><R><E><S><P><V><D><C><S><V><S><K><C><S><K><L><V><G><G><G><E><S><N><P><M><N><Y><N><S><Y><M><D... | Sequence-specific transcriptional activator . Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.<BOP> | Q01543 |
Q9UIX4 | KCNG1_HUMAN | kH2 | Homo | <M><T><L><L><P><G><D><N><S><D><Y><D><Y><S><A><L><S><C><T><S><D><A><S><F><H><P><A><F><L><P><Q><R><Q><A><I><K><G><A><F><Y><R><R><A><Q><R><L><R><P><Q><D><E><P><R><Q><G><C><Q><P><E><D><R><R><R><R><I><I><I><N><V><G><G><I><K><Y><S><L><P><W><T><T><L><D><E><F><P><L><T><R><L><G><Q><L><K><A><C><T><N><F><D><D><I><L><N><V><C><D><D... | Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 .<BOP> | Q9UIX4 |
P05155 | IC1_HUMAN | Serpin G1 | Homo | <M><A><S><R><L><T><L><L><T><L><L><L><L><L><L><A><G><D><R><A><S><S><N><P><N><A><T><S><S><S><S><Q><D><P><E><S><L><Q><D><R><G><E><G><K><V><A><T><T><V><I><S><K><M><L><F><V><E><P><I><L><E><V><S><S><L><P><T><T><N><S><T><T><N><S><A><T><K><I><T><A><N><T><T><D><E><P><T><T><Q><P><T><T><E><P><T><T><Q><P><T><I><Q><P><T><Q><P><T><T... | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generat... | P05155 |
P49798 | RGS4_HUMAN | Regulator of G-protein signaling 4 | Homo | <M><C><K><G><L><A><G><L><P><A><S><C><L><R><S><A><K><D><M><K><H><R><L><G><F><L><L><Q><K><S><D><S><C><E><H><N><S><S><H><N><K><K><D><K><V><V><I><C><Q><R><V><S><Q><E><E><V><K><K><W><A><E><S><L><E><N><L><I><S><H><E><C><G><L><A><A><F><K><A><F><L><K><S><E><Y><S><E><E><N><I><D><F><W><I><S><C><E><E><Y><K><K><I><K><S><P><S><K><L... | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.<BOP> | P49798 |
Q6PHW0 | IYD1_HUMAN | Iodotyrosine dehalogenase 1 | Homo | <M><Y><F><L><T><P><I><L><V><A><I><L><C><I><L><V><V><W><I><F><K><N><A><D><R><S><M><E><K><K><K><G><E><P><R><T><R><A><E><A><R><P><W><V><D><E><D><L><K><D><S><S><D><L><H><Q><A><E><E><D><A><D><E><W><Q><E><S><E><E><N><V><E><H><I><P><F><S><H><N><H><Y><P><E><K><E><M><V><K><R><S><Q><E><F><Y><E><L><L><N><K><R><R><S><V><R><F><I><S... | Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine . During thyroid hormone biosynthesis, facilitates iodide salvage by catalysing the oxidative NADPH-dependent deiodination of the halogenated by-products of thyroid hormone producti... | Q6PHW0 |
P51671 | CCL11_HUMAN | Small-inducible cytokine A11 | Homo | <M><K><V><S><A><A><L><L><W><L><L><L><I><A><A><A><F><S><P><Q><G><L><A><G><P><A><S><V><P><T><T><C><C><F><N><L><A><N><R><K><I><P><L><Q><R><L><E><S><Y><R><R><I><T><S><G><K><C><P><Q><K><A><V><I><F><K><T><K><L><A><K><D><I><C><A><D><P><K><K><K><W><V><Q><D><S><M><K><Y><L><D><Q><K><S><P><T><P><K><P> | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions . Binds to CCR3 .<BOP> | P51671 |
Q5TH74 | STPG1_HUMAN | Sperm-tail PG-rich repeat-containing protein 1 | Homo | <M><D><N><S><A><Q><K><N><E><R><T><G><K><H><P><R><R><A><S><E><V><Q><K><G><F><T><A><A><Y><P><T><Q><S><S><I><P><F><K><S><Q><A><S><V><I><P><E><S><E><K><K><G><F><N><S><Q><A><K><R><F><P><H><K><K><N><D><I><P><G><P><G><F><Y><N><V><I><H><Q><S><P><V><S><N><S><V><S><L><S><K><K><G><T><C><M><F><P><S><M><C><A><R><L><D><T><I><I><S><K... | May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.<BOP> | Q5TH74 |
P32246 | CCR1_HUMAN | RANTES-R | Homo | <M><E><T><P><N><T><T><E><D><Y><D><T><T><T><E><F><D><Y><G><D><A><T><P><C><Q><K><V><N><E><R><A><F><G><A><Q><L><L><P><P><L><Y><S><L><V><F><V><I><G><L><V><G><N><I><L><V><V><L><V><L><V><Q><Y><K><R><L><K><N><M><T><S><I><Y><L><L><N><L><A><I><S><D><L><L><F><L><F><T><L><P><F><W><I><D><Y><K><L><K><D><D><W><V><F><G><D><A><M><C><K... | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.<BOP> | P32246 |
Q9BSV6 | SEN34_HUMAN | tRNA-intron endonuclease Sen34 | Homo | <M><L><V><V><E><V><A><N><G><R><S><L><V><W><G><A><E><A><V><Q><A><L><R><E><R><L><G><V><G><G><R><T><V><G><A><L><P><R><G><P><R><Q><N><S><R><L><G><L><P><L><L><L><M><P><E><E><A><R><L><L><A><E><I><G><A><V><T><L><V><S><A><P><R><P><D><S><R><H><H><S><L><A><L><T><S><F><K><R><Q><Q><E><E><S><F><Q><E><Q><S><A><L><A><A><E><A><R><E><T... | Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cy... | Q9BSV6 |
P21452 | NK2R_HUMAN | Tachykinin receptor 2 | Homo | <M><G><T><C><D><I><V><T><E><A><N><I><S><S><G><P><E><S><N><T><T><G><I><T><A><F><S><M><P><S><W><Q><L><A><L><W><A><T><A><Y><L><A><L><V><L><V><A><V><T><G><N><A><I><V><I><W><I><I><L><A><H><R><R><M><R><T><V><T><N><Y><F><I><V><N><L><A><L><A><D><L><C><M><A><A><F><N><A><A><F><N><F><V><Y><A><S><H><N><I><W><Y><F><G><R><A><F><C><Y... | This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.<BOP> | P21452 |
P54803 | GALC_HUMAN | Galactosylceramide beta-galactosidase | Homo | <M><A><E><W><L><L><S><A><S><W><Q><R><R><A><K><A><M><T><A><A><A><G><S><A><G><R><A><A><V><P><L><L><L><C><A><L><L><A><P><G><G><A><Y><V><L><D><D><S><D><G><L><G><R><E><F><D><G><I><G><A><V><S><G><G><G><A><T><S><R><L><L><V><N><Y><P><E><P><Y><R><S><Q><I><L><D><Y><L><F><K><P><N><F><G><A><S><L><H><I><L><K><V><E><I><G><G><D><G><Q... | Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine . Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon .<BOP> | P54803 |
Q6ZNW5 | GDPP1_HUMAN | GDP-D-glucose phosphorylase 1 | Homo | <M><A><L><P><H><D><S><N><E><T><S><Y><L><L><P><P><N><N><E><D><W><G><R><Q><T><I><P><D><F><V><Y><G><Q><K><D><L><M><A><E><G><I><Q><W><P><R><N><A><P><G><I><P><D><A><L><P><Q><S><P><F><D><A><A><L><C><S><A><W><K><Q><R><V><E><L><G><L><F><R><Y><R><L><R><E><L><Q><T><Q><I><L><P><G><A><V><G><F><V><A><Q><L><N><V><E><R><G><V><Q><R><R... | Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.<BOP> | Q6ZNW5 |
P15531 | NDKA_HUMAN | Tumor metastatic process-associated protein | Homo | <M><A><N><C><E><R><T><F><I><A><I><K><P><D><G><V><Q><R><G><L><V><G><E><I><I><K><R><F><E><Q><K><G><F><R><L><V><G><L><K><F><M><Q><A><S><E><D><L><L><K><E><H><Y><V><D><L><K><D><R><P><F><F><A><G><L><V><K><Y><M><H><S><G><P><V><V><A><M><V><W><E><G><L><N><V><V><K><T><G><R><V><M><L><G><E><T><N><P><A><D><S><K><P><G><T><I><R><G><D... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyr... | P15531 |
Q86YS6 | RAB43_HUMAN | Ras-related protein Rab-41 | Homo | <M><A><G><P><G><P><G><P><G><D><P><D><E><Q><Y><D><F><L><F><K><L><V><L><V><G><D><A><S><V><G><K><T><C><V><V><Q><R><F><K><T><G><A><F><S><E><R><Q><G><S><T><I><G><V><D><F><T><M><K><T><L><E><I><Q><G><K><R><V><K><L><Q><I><W><D><T><A><G><Q><E><R><F><R><T><I><T><Q><S><Y><Y><R><S><A><N><G><A><I><L><A><Y><D><I><T><K><R><S><S><F><L... | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsi... | Q86YS6 |
Q9NWX5 | ASB6_HUMAN | Ankyrin repeat and SOCS box protein 6 | Homo | <M><P><F><L><H><G><F><R><R><I><I><F><E><Y><Q><P><L><V><D><A><I><L><G><S><L><G><I><Q><D><P><E><R><Q><E><S><L><D><R><P><S><Y><V><A><S><E><E><S><R><I><L><V><L><T><E><L><L><E><R><K><A><H><S><P><F><Y><Q><E><G><V><S><N><A><L><L><K><M><A><E><L><G><L><T><R><A><A><D><V><L><L><R><H><G><A><N><L><N><F><E><D><P><V><T><Y><Y><T><A><L... | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q9NWX5 |
Q96PK6 | RBM14_HUMAN | Synaptotagmin-interacting protein | Homo | <M><K><I><F><V><G><N><V><D><G><A><D><T><T><P><E><E><L><A><A><L><F><A><P><Y><G><T><V><M><S><C><A><V><M><K><Q><F><A><F><V><H><M><R><E><N><A><G><A><L><R><A><I><E><A><L><H><G><H><E><L><R><P><G><R><A><L><V><V><E><M><S><R><P><R><P><L><N><T><W><K><I><F><V><G><N><V><S><A><A><C><T><S><Q><E><L><R><S><L><F><E><R><R><G><R><V><I><E... | Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1 . Regulates centriole biogenesis by supp... | Q96PK6 |
Q9NQN1 | OR2S1_HUMAN | Olfactory receptor OR9-3 | Homo | <M><E><K><A><N><E><T><S><P><V><M><G><F><V><L><L><R><L><S><A><H><P><E><L><E><K><T><F><F><V><L><I><L><L><M><Y><L><V><I><L><L><G><N><G><V><L><I><L><V><T><I><L><D><S><R><L><H><T><P><M><Y><F><F><L><G><N><L><S><F><L><D><I><C><F><T><T><S><S><V><P><L><V><L><D><S><F><L><T><P><Q><E><T><I><S><F><S><A><C><A><V><Q><M><A><L><S><F><A... | Odorant receptor.<BOP> | Q9NQN1 |
Q99967 | CITE2_HUMAN | P35srj | Homo | <M><A><D><H><M><M><A><M><N><H><G><R><F><P><D><G><T><N><G><L><H><H><H><P><A><H><R><M><G><M><G><Q><F><P><S><P><H><H><H><Q><Q><Q><Q><P><Q><H><A><F><N><A><L><M><G><E><H><I><H><Y><G><A><G><N><M><N><A><T><S><G><I><R><H><A><M><G><P><G><T><V><N><G><G><H><P><P><S><A><L><A><P><A><A><R><F><N><N><S><Q><F><M><G><P><P><V><A><S><Q><G... | Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the... | Q99967 |
P08637 | FCG3A_HUMAN | IgG Fc receptor III-2 | Homo | <M><W><Q><L><L><L><P><T><A><L><L><L><L><V><S><A><G><M><R><T><E><D><L><P><K><A><V><V><F><L><E><P><Q><W><Y><R><V><L><E><K><D><S><V><T><L><K><C><Q><G><A><Y><S><P><E><D><N><S><T><Q><W><F><H><N><E><S><L><I><S><S><Q><A><S><S><Y><F><I><D><A><A><T><V><D><D><S><G><E><Y><R><C><Q><T><N><L><S><T><L><S><D><P><V><Q><L><E><V><H><I><G... | (Microbial infection) Involved in Dengue virus pathogenesis via antibody-dependent enhancement (ADE) mechanism. Secondary infection with Dengue virus triggers elevated levels of afucosylated non-neutralizing IgG1s with reactivity to viral envelope/E protein. Viral antigen-IgG1 complexes bind with high affinity to FCGR3... | P08637 |
Q9NQ55 | SSF1_HUMAN | Peter Pan homolog | Homo | <M><G><Q><S><G><R><S><R><H><Q><K><R><A><R><A><Q><A><Q><L><R><N><L><E><A><Y><A><A><N><P><H><S><F><V><F><T><R><G><C><T><G><R><N><I><R><Q><L><S><L><D><V><R><R><V><M><E><P><L><T><A><S><R><L><Q><V><R><K><K><N><S><L><K><D><C><V><A><V><A><G><P><L><G><V><T><H><F><L><I><L><S><K><T><E><T><N><V><Y><F><K><L><M><R><L><P><G><G><P><T... | May have a role in cell growth.<BOP> | Q9NQ55 |
Q15113 | PCOC1_HUMAN | Type I procollagen COOH-terminal proteinase enhancer | Homo | <M><L><P><A><A><T><A><S><L><L><G><P><L><L><T><A><C><A><L><L><P><F><A><Q><G><Q><T><P><N><Y><T><R><P><V><F><L><C><G><G><D><V><K><G><E><S><G><Y><V><A><S><E><G><F><P><N><L><Y><P><P><N><K><E><C><I><W><T><I><T><V><P><E><G><Q><T><V><S><L><S><F><R><V><F><D><L><E><L><H><P><A><C><R><Y><D><A><L><E><V><F><A><G><S><G><T><S><G><Q><R... | C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.<BOP> | Q15113 |
P14316 | IRF2_HUMAN | Interferon regulatory factor 2 | Homo | <M><P><V><E><R><M><R><M><R><P><W><L><E><E><Q><I><N><S><N><T><I><P><G><L><K><W><L><N><K><E><K><K><I><F><Q><I><P><W><M><H><A><A><R><H><G><W><D><V><E><K><D><A><P><L><F><R><N><W><A><I><H><T><G><K><H><Q><P><G><V><D><K><P><D><P><K><T><W><K><A><N><F><R><C><A><M><N><S><L><P><D><I><E><E><V><K><D><K><S><I><K><K><G><N><N><A><F><R... | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle ... | P14316 |
Q9UQQ1 | NALDL_HUMAN | N-acetylated-alpha-linked acidic dipeptidase-like protein | Homo | <M><Q><W><T><K><V><L><G><L><G><L><G><A><A><A><L><L><G><L><G><I><I><L><G><H><F><A><I><P><K><K><A><N><S><L><A><P><Q><D><L><D><L><E><I><L><E><T><V><M><G><Q><L><D><A><H><R><I><R><E><N><L><R><E><L><S><R><E><P><H><L><A><S><S><P><R><D><E><D><L><V><Q><L><L><L><Q><R><W><K><D><P><E><S><G><L><D><S><A><E><A><S><T><Y><E><V><L><L><S... | Aminopeptidase with broad substrate specificity. Has lower activity with substrates that have Asp or Glu in the P2' position, or Pro in the P3' position. Lacks activity with substrates that have both Pro in the P3' position and Asp or Glu in the P2' position . Lacks carboxypeptidase activity. Lacks dipeptidyl-peptidase... | Q9UQQ1 |
P35080 | PROF2_HUMAN | Profilin II | Homo | <M><A><G><W><Q><S><Y><V><D><N><L><M><C><D><G><C><C><Q><E><A><A><I><V><G><Y><C><D><A><K><Y><V><W><A><A><T><A><G><G><V><F><Q><S><I><T><P><I><E><I><D><M><I><V><G><K><D><R><E><G><F><F><T><N><G><L><T><L><G><A><K><K><C><S><V><I><R><D><S><L><Y><V><D><G><D><C><T><M><D><I><R><T><K><S><Q><G><G><E><P><T><Y><N><V><A><V><G><R><A><G... | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.<BOP> | P35080 |
Q99687 | MEIS3_HUMAN | Meis1-related protein 2 | Homo | <M><A><R><R><Y><D><E><L><P><H><Y><P><G><I><V><D><G><P><A><A><L><A><S><F><P><E><T><V><P><A><V><P><G><P><Y><G><P><H><R><P><P><Q><P><L><P><P><G><L><D><S><D><G><L><K><R><E><K><D><E><I><Y><G><H><P><L><F><P><L><L><A><L><V><F><E><K><C><E><L><A><T><C><S><P><R><D><G><A><G><A><G><L><G><T><P><P><G><G><D><V><C><S><S><D><S><F><N><E... | Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.<BOP> | Q99687 |
I0J062 | PANO1_HUMAN | Proapoptotic nucleolar protein 1 | Homo | <M><G><V><R><L><R><V><W><P><A><A><P><H><S><I><S><R><C><P><R><P><L><G><A><V><L><S><I><L><L><A><G><G><S><R><K><G><T><P><T><A><R><C><L><G><Q><R><T><K><E><K><R><V><G><G><R><S><L><R><S><E><A><G><S><G><P><C><P><T><A><G><A><Q><P><T><A><P><S><S><A><W><P><P><R><L><R><P><R><T><C><P><Q><M><S><G><E><L><P><R><V><R><P><T><R><V><G><L... | Apoptosis-inducing protein that modulates the tumor suppressor function of CDKN2A/p14ARF. Enhances the stability of CDKN2A/p14ARF protein by protecting it from degradation. May act as a tumor suppressor .<BOP> | I0J062 |
P08697 | A2AP_HUMAN | Serpin F2 | Homo | <M><A><L><L><W><G><L><L><V><L><S><W><S><C><L><Q><G><P><C><S><V><F><S><P><V><S><A><M><E><P><L><G><R><Q><L><T><S><G><P><N><Q><E><Q><V><S><P><L><T><L><L><K><L><G><N><Q><E><P><G><G><Q><T><A><L><K><S><P><P><G><V><C><S><R><D><P><T><P><E><Q><T><H><R><L><A><R><A><M><M><A><F><T><A><D><L><F><S><L><V><A><Q><T><S><T><C><P><N><L><I... | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.<BOP> | P08697 |
P09228 | CYTT_HUMAN | Cystatin-S5 | Homo | <M><A><W><P><L><C><T><L><L><L><L><L><A><T><Q><A><V><A><L><A><W><S><P><Q><E><E><D><R><I><I><E><G><G><I><Y><D><A><D><L><N><D><E><R><V><Q><R><A><L><H><F><V><I><S><E><Y><N><K><A><T><E><D><E><Y><Y><R><R><L><L><R><V><L><R><A><R><E><Q><I><V><G><G><V><N><Y><F><F><D><I><E><V><G><R><T><I><C><T><K><S><Q><P><N><L><D><T><C><A><F><H... | Thiol protease inhibitor.<BOP> | P09228 |
P63125 | VPK25_HUMAN | Proteinase | Homo | <W><A><S><Q><V><S><E><N><R><P><V><C><K><A><I><I><Q><G><K><Q><F><E><G><L><V><D><T><G><A><D><V><S><I><I><A><L><N><Q><W><P><K><N><W><P><K><Q><K><A><V><T><G><L><V><G><V><G><T><A><S><E><V><Y><Q><S><T><E><I><L><H><C><L><G><P><D><N><Q><E><S><T><V><Q><P><M><I><T><S><I><P><L><N><L><W><G><R><D><L><L><Q><Q><W><G><A><E><I><T><M><P... | Retroviral proteases have roles in processing of the primary translation products and the maturation of the viral particle. Endogenous Pro proteins may have kept, lost or modified their original function during evolution. This endogenous protein has retained most of the characteristics of retroviral proteases.<BOP> | P63125 |
Q7Z7C7 | STRA8_HUMAN | Stimulated by retinoic acid gene 8 protein homolog | Homo | <M><G><K><I><D><V><D><K><I><L><F><F><N><Q><E><I><R><L><W><Q><L><I><M><A><T><P><E><E><N><S><N><P><H><D><R><A><T><P><Q><L><P><A><Q><L><Q><E><L><E><H><R><V><A><R><R><R><L><S><Q><A><R><H><R><A><T><L><A><A><L><F><N><N><L><R><K><T><V><Y><S><Q><S><D><L><I><A><S><K><W><Q><V><L><N><K><A><K><S><H><I><P><E><L><E><Q><T><L><D><N><L... | Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic in... | Q7Z7C7 |
Q99075 | HBEGF_HUMAN | Diphtheria toxin receptor | Homo | <M><K><L><L><P><S><V><V><L><K><L><F><L><A><A><V><L><S><A><L><V><T><G><E><S><L><E><R><L><R><R><G><L><A><A><G><T><S><N><P><D><P><P><T><V><S><T><D><Q><L><L><P><L><G><G><G><R><D><R><K><V><R><D><L><Q><E><A><D><L><D><L><L><R><V><T><L><S><S><K><P><Q><A><L><A><T><P><N><K><E><E><H><G><K><R><K><K><K><G><K><G><L><G><K><K><R><D><P... | Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bi... | Q99075 |
P10696 | PPBN_HUMAN | Placental alkaline phosphatase-like | Homo | <M><Q><G><P><W><V><L><L><L><L><G><L><R><L><Q><L><S><L><G><I><I><P><V><E><E><E><N><P><D><F><W><N><R><Q><A><A><E><A><L><G><A><A><K><K><L><Q><P><A><Q><T><A><A><K><N><L><I><I><F><L><G><D><G><M><G><V><S><T><V><T><A><A><R><I><L><K><G><Q><K><K><D><K><L><G><P><E><T><F><L><A><M><D><R><F><P><Y><V><A><L><S><K><T><Y><S><V><D><K><H... | Alkaline phosphatase that can hydrolyze various phosphate compounds.<BOP> | P10696 |
P22492 | H1T_HUMAN | Testicular H1 histone | Homo | <M><S><E><T><V><P><A><A><S><A><S><A><G><V><A><A><M><E><K><L><P><T><K><K><R><G><R><K><P><A><G><L><I><S><A><S><R><K><V><P><N><L><S><V><S><K><L><I><T><E><A><L><S><V><S><Q><E><R><V><G><M><S><L><V><A><L><K><K><A><L><A><A><A><G><Y><D><V><E><K><N><N><S><R><I><K><L><S><L><K><S><L><V><N><K><G><I><L><V><Q><T><R><G><T><G><A><S><G... | Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes . Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination . Histones H1 act as linkers that bind t... | P22492 |
Q969K4 | ABTB1_HUMAN | Elongation factor 1A-binding protein | Homo | <M><D><T><S><D><L><F><A><S><C><R><K><G><D><V><G><R><V><R><Y><L><L><E><Q><R><D><V><E><V><N><V><R><D><K><W><D><S><T><P><L><Y><Y><A><C><L><C><G><H><E><E><L><V><L><Y><L><L><A><N><G><A><R><C><E><A><N><T><F><D><G><E><R><C><L><Y><G><A><L><S><D><P><I><R><R><A><L><R><D><Y><K><Q><V><T><A><S><C><R><R><R><D><Y><Y><D><D><F><L><Q><R... | May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.<BOP> | Q969K4 |
Q8NGZ4 | OR2G3_HUMAN | Olfactory receptor OR1-33 | Homo | <M><G><L><G><N><E><S><S><L><M><D><F><I><L><L><G><F><S><D><H><P><R><L><E><A><V><L><F><V><F><V><L><F><F><Y><L><L><T><L><V><G><N><F><T><I><I><I><I><S><Y><L><D><P><P><L><H><T><P><M><Y><F><F><L><S><N><L><S><L><L><D><I><C><F><T><T><S><L><A><P><Q><T><L><V><N><L><Q><R><P><K><K><T><I><T><Y><G><G><C><V><A><Q><L><Y><I><S><L><A><L... | Odorant receptor.<BOP> | Q8NGZ4 |
Q9H2F9 | CCD68_HUMAN | Cutaneous T-cell lymphoma-associated antigen se57-1 | Homo | <M><T><T><V><T><V><T><T><E><I><P><P><R><D><K><M><E><D><N><S><A><L><Y><E><S><T><S><A><H><I><I><E><E><T><E><Y><V><K><K><I><R><T><T><L><Q><K><I><R><T><Q><M><F><K><D><E><I><R><H><D><S><T><N><H><K><L><D><A><K><H><C><G><N><L><Q><Q><G><S><D><S><E><M><D><P><S><C><C><S><L><D><L><L><M><K><K><I><K><G><K><D><L><Q><L><L><E><M><N><K... | Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells . Together with CCDC120, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly .<BOP> | Q9H2F9 |
A6NMZ2 | SNTAN_HUMAN | S100 calcium-binding protein A1-like | Homo | <M><G><G><C><M><H><S><T><Q><D><K><S><L><H><L><E><G><D><P><N><P><S><A><A><P><T><S><T><C><A><P><R><K><M><P><K><R><I><S><I><S><K><Q><L><A><S><V><K><A><L><R><K><C><S><D><L><E><K><A><I><A><T><T><A><L><I><F><R><N><S><S><D><S><D><G><K><L><E><K><A><I><A><K><D><L><L><Q><T><Q><F><R><N><F><A><E><G><Q><E><T><K><P><K><Y><R><E><I><L... | May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.<BOP> | A6NMZ2 |
O43291 | SPIT2_HUMAN | Placental bikunin | Homo | <M><A><Q><L><C><G><L><R><R><S><R><A><F><L><A><L><L><G><S><L><L><L><S><G><V><L><A><A><D><R><E><R><S><I><H><D><F><C><L><V><S><K><V><V><G><R><C><R><A><S><M><P><R><W><W><Y><N><V><T><D><G><S><C><Q><L><F><V><Y><G><G><C><D><G><N><S><N><N><Y><L><T><K><E><E><C><L><K><K><C><A><T><V><T><E><N><A><T><G><D><L><A><T><S><R><N><A><A><D... | Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.<BOP> | O43291 |
O43448 | KCAB3_HUMAN | Kv-beta-3 | Homo | <M><Q><V><S><I><A><C><T><E><Q><N><L><R><S><R><S><S><E><D><R><L><C><G><P><R><P><G><P><G><G><G><N><G><G><P><A><G><G><G><H><G><N><P><P><G><G><G><G><S><G><P><K><A><R><A><A><L><V><P><R><P><P><A><P><A><G><A><L><R><E><S><T><G><R><G><T><G><M><K><Y><R><N><L><G><K><S><G><L><R><V><S><C><L><G><L><G><T><W><V><T><F><G><S><Q><I><S><D... | Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.<BOP> | O43448 |
Q96A72 | MGN2_HUMAN | Protein mago nashi homolog 2 | Homo | <M><A><V><A><S><D><F><Y><L><R><Y><Y><V><G><H><K><G><K><F><G><H><E><F><L><E><F><E><F><R><P><D><G><K><L><R><Y><A><N><N><S><N><Y><K><N><D><V><M><I><R><K><E><A><Y><V><H><K><S><V><M><E><E><L><K><R><I><I><D><D><S><E><I><T><K><E><D><D><A><L><W><P><P><P><D><R><V><G><R><Q><E><L><E><I><V><I><G><D><E><H><I><S><F><T><T><S><K><I><G... | Required for pre-mRNA splicing as component of the spliceosome . Plays a redundant role with MAGOH in the exon junction complex and in the nonsense-mediated decay (NMD) pathway .<BOP> | Q96A72 |
Q8NGJ0 | OR5A1_HUMAN | Olfactory receptor OR11-249 | Homo | <M><S><I><T><K><A><W><N><S><S><S><V><T><M><F><I><L><L><G><F><T><D><H><P><E><L><Q><A><L><L><F><V><T><F><L><G><I><Y><L><T><T><L><A><W><N><L><A><L><I><F><L><I><R><G><D><T><H><L><H><T><P><M><Y><F><F><L><S><N><L><S><F><I><D><I><C><Y><S><S><A><V><A><P><N><M><L><T><D><F><F><W><E><Q><K><T><I><S><F><V><G><C><A><A><Q><F><F><F><F... | Odorant receptor.<BOP> | Q8NGJ0 |
Q16254 | E2F4_HUMAN | Transcription factor E2F4 | Homo | <M><A><E><A><G><P><Q><A><P><P><P><P><G><T><P><S><R><H><E><K><S><L><G><L><L><T><T><K><F><V><S><L><L><Q><E><A><K><D><G><V><L><D><L><K><L><A><A><D><T><L><A><V><R><Q><K><R><R><I><Y><D><I><T><N><V><L><E><G><I><G><L><I><E><K><K><S><K><N><S><I><Q><W><K><G><V><G><P><G><C><N><T><R><E><I><A><D><K><L><I><E><L><K><A><E><I><E><E><L... | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression ... | Q16254 |
Q8TDS5 | OXER1_HUMAN | G-protein coupled receptor TG1019 | Homo | <M><L><C><H><R><G><G><Q><L><I><V><P><I><I><P><L><C><P><E><H><S><C><R><G><R><R><L><Q><N><L><L><S><G><P><W><P><K><Q><P><M><E><L><H><N><L><S><S><P><S><P><S><L><S><S><S><V><L><P><P><S><F><S><P><S><P><S><S><A><P><S><A><F><T><T><V><G><G><S><S><G><G><P><C><H><P><T><S><S><S><L><V><S><A><F><L><A><P><I><L><A><L><E><F><V><L><G><L... | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.<BOP> | Q8TDS5 |
A6NL26 | OR5BL_HUMAN | Olfactory receptor 5B21 | Homo | <M><E><N><S><T><E><V><T><E><F><I><L><L><G><L><T><D><D><P><N><L><Q><I><P><L><L><L><A><F><L><F><I><Y><L><I><T><L><L><G><N><G><G><M><M><V><I><I><H><S><D><S><H><L><H><T><P><M><Y><F><F><L><S><N><L><S><L><V><D><L><G><Y><S><S><A><V><A><P><K><T><V><A><A><L><R><S><G><D><K><A><I><S><Y><D><G><C><A><A><Q><F><F><F><F><V><G><F><A><T... | Odorant receptor.<BOP> | A6NL26 |
Q6UWU4 | CF089_HUMAN | Amfion | Homo | <M><D><L><A><A><N><E><I><S><I><Y><D><K><L><S><E><T><V><D><L><V><R><Q><T><G><H><Q><C><G><M><S><E><K><A><I><E><K><F><I><R><Q><L><L><E><K><N><E><P><Q><R><P><P><P><Q><Y><P><L><L><I><V><V><Y><K><V><L><A><T><L><G><L><I><L><L><T><A><Y><F><V><I><Q><P><F><S><P><L><A><P><E><P><V><L><S><G><A><H><T><W><R><S><L><I><H><H><I><R><L><M... | Exhibits histone deacetylase (HDAC) enhancer properties . May play a role in cell cycle progression and wound repair of bronchial epithelial cells .<BOP> | Q6UWU4 |
P52945 | PDX1_HUMAN | Somatostatin-transactivating factor 1 | Homo | <M><N><G><E><E><Q><Y><Y><A><A><T><Q><L><Y><K><D><P><C><A><F><Q><R><G><P><A><P><E><F><S><A><S><P><P><A><C><L><Y><M><G><R><Q><P><P><P><P><P><P><H><P><F><P><G><A><L><G><A><L><E><Q><G><S><P><P><D><I><S><P><Y><E><V><P><P><L><A><D><D><P><A><V><A><H><L><H><H><H><L><P><A><Q><L><A><L><P><H><P><P><A><G><P><F><P><E><G><A><E><P><G... | Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation ... | P52945 |
P13807 | GYS1_HUMAN | Glycogen [starch] synthase, muscle | Homo | <M><P><L><N><R><T><L><S><M><S><S><L><P><G><L><E><D><W><E><D><E><F><D><L><E><N><A><V><L><F><E><V><A><W><E><V><A><N><K><V><G><G><I><Y><T><V><L><Q><T><K><A><K><V><T><G><D><E><W><G><D><N><Y><F><L><V><G><P><Y><T><E><Q><G><V><R><T><Q><V><E><L><L><E><A><P><T><P><A><L><K><R><T><L><D><S><M><N><S><K><G><C><K><V><Y><F><G><R><W><L... | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.<BOP> | P13807 |
Q96R05 | RET7_HUMAN | Cellular retinoic acid-binding protein IV | Homo | <M><P><A><D><L><S><G><T><W><T><L><L><S><S><D><N><F><E><G><Y><M><L><A><L><G><I><D><F><A><T><R><K><I><A><K><L><L><K><P><Q><K><V><I><E><Q><N><G><D><S><F><T><I><H><T><N><S><S><L><R><N><Y><F><V><K><F><K><V><G><E><E><F><D><E><D><N><R><G><L><D><N><R><K><C><K><S><L><V><I><W><D><N><D><R><L><T><C><I><Q><K><G><E><K><K><N><R><G><W... | Intracellular transport of retinol.<BOP> | Q96R05 |
O95231 | VENTX_HUMAN | VENT-like homeobox protein 2 | Homo | <M><R><L><S><S><S><P><P><R><G><P><Q><Q><L><S><S><F><G><S><V><D><W><L><S><Q><S><S><C><S><G><P><T><H><T><P><R><P><A><D><F><S><L><G><S><L><P><G><P><G><Q><T><S><G><A><R><E><P><P><Q><A><V><S><I><K><E><A><A><G><S><S><N><L><P><A><P><E><R><T><M><A><G><L><S><K><E><P><N><T><L><R><A><P><R><V><R><T><A><F><T><M><E><Q><V><R><T><L><E... | May be involved in ventralization.<BOP> | O95231 |
P05015 | IFN16_HUMAN | Interferon alpha-WA | Homo | <M><A><L><S><F><S><L><L><M><A><V><L><V><L><S><Y><K><S><I><C><S><L><G><C><D><L><P><Q><T><H><S><L><G><N><R><R><A><L><I><L><L><A><Q><M><G><R><I><S><H><F><S><C><L><K><D><R><Y><D><F><G><F><P><Q><E><V><F><D><G><N><Q><F><Q><K><A><Q><A><I><S><A><F><H><E><M><I><Q><Q><T><F><N><L><F><S><T><K><D><S><S><A><A><W><D><E><T><L><L><D><K... | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.<BOP> | P05015 |
P46439 | GSTM5_HUMAN | GSTM5-5 | Homo | <M><P><M><T><L><G><Y><W><D><I><R><G><L><A><H><A><I><R><L><L><L><E><Y><T><D><S><S><Y><V><E><K><K><Y><T><L><G><D><A><P><D><Y><D><R><S><Q><W><L><N><E><K><F><K><L><G><L><D><F><P><N><L><P><Y><L><I><D><G><A><H><K><I><T><Q><S><N><A><I><L><R><Y><I><A><R><K><H><N><L><C><G><E><T><E><E><E><K><I><R><V><D><I><L><E><N><Q><V><M><D><N... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<BOP> | P46439 |
P26373 | RL13_HUMAN | Large ribosomal subunit protein eL13 | Homo | <M><A><P><S><R><N><G><M><V><L><K><P><H><F><H><K><D><W><Q><R><R><V><A><T><W><F><N><Q><P><A><R><K><I><R><R><R><K><A><R><Q><A><K><A><R><R><I><A><P><R><P><A><S><G><P><I><R><P><I><V><R><C><P><T><V><R><Y><H><T><K><V><R><A><G><R><G><F><S><L><E><E><L><R><V><A><G><I><H><K><K><V><A><R><T><I><G><I><S><V><D><P><R><R><R><N><K><S><T... | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains... | P26373 |
P23280 | CAH6_HUMAN | Secreted carbonic anhydrase | Homo | <M><R><A><L><V><L><L><L><S><L><F><L><L><G><G><Q><A><Q><H><V><S><D><W><T><Y><S><E><G><A><L><D><E><A><H><W><P><Q><H><Y><P><A><C><G><G><Q><R><Q><S><P><I><N><L><Q><R><T><K><V><R><Y><N><P><S><L><K><G><L><N><M><T><G><Y><E><T><Q><A><G><E><F><P><M><V><N><N><G><H><T><V><Q><I><S><L><P><S><T><M><R><M><T><V><A><D><G><T><V><Y><I><A... | Reversible hydration of carbon dioxide. Its role in saliva is unknown.<BOP> | P23280 |
Q8TDU6 | GPBAR_HUMAN | hBG37 | Homo | <M><T><P><N><S><T><G><E><V><P><S><P><I><P><K><G><A><L><G><L><S><L><A><L><A><S><L><I><I><T><A><N><L><L><L><A><L><G><I><A><W><D><R><R><L><R><S><P><P><A><G><C><F><F><L><S><L><L><L><A><G><L><L><T><G><L><A><L><P><T><L><P><G><L><W><N><Q><S><R><R><G><Y><W><S><C><L><L><V><Y><L><A><P><N><F><S><F><L><S><L><L><A><N><L><L><L><V><H... | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.<BOP> | Q8TDU6 |
Q9H672 | ASB7_HUMAN | Ankyrin repeat and SOCS box protein 7 | Homo | <M><L><H><H><H><C><R><R><N><P><E><L><Q><E><E><L><Q><I><Q><A><A><V><A><A><G><D><V><H><T><V><R><K><M><L><E><Q><G><Y><S><P><N><G><R><D><A><N><G><W><T><L><L><H><F><S><A><A><R><G><K><E><R><C><V><R><V><F><L><E><H><G><A><D><P><T><V><K><D><L><I><G><G><F><T><A><L><H><Y><A><A><M><H><G><R><A><R><I><A><R><L><M><L><E><S><E><Y><R><S... | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q9H672 |
P57081 | WDR4_HUMAN | WD repeat-containing protein 4 | Homo | <M><A><G><S><V><G><L><A><L><C><G><Q><T><L><V><V><R><G><G><S><R><F><L><A><T><S><I><A><S><S><D><D><D><S><L><F><I><Y><D><C><S><A><A><E><K><K><S><Q><E><N><K><G><E><D><A><P><L><D><Q><G><S><G><A><I><L><A><S><T><F><S><K><S><G><S><Y><F><A><L><T><D><D><S><K><R><L><I><L><F><R><T><K><P><W><Q><C><L><S><V><R><T><V><A><R><R><C><T><A... | Non-catalytic component of a methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) . In the methyltransferase complex, it is required to stabilize and induce conformational changes of the catalytic subunit . Required for the fo... | P57081 |
Q8WVN8 | UB2Q2_HUMAN | Ubiquitin-protein ligase Q2 | Homo | <M><S><V><S><G><L><K><A><E><L><K><F><L><A><S><I><F><D><K><N><H><E><R><F><R><I><V><S><W><K><L><D><E><L><H><C><Q><F><L><V><P><Q><Q><G><S><P><H><S><L><P><P><P><L><T><L><H><C><N><I><T><E><S><Y><P><S><S><S><P><I><W><F><V><D><S><E><D><P><N><L><T><S><V><L><E><R><L><E><D><T><K><N><N><N><L><L><R><Q><Q><L><K><W><L><I><C><E><L><C... | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.<BOP> | Q8WVN8 |
Q16143 | SYUB_HUMAN | Beta-synuclein | Homo | <M><D><V><F><M><K><G><L><S><M><A><K><E><G><V><V><A><A><A><E><K><T><K><Q><G><V><T><E><A><A><E><K><T><K><E><G><V><L><Y><V><G><S><K><T><R><E><G><V><V><Q><G><V><A><S><V><A><E><K><T><K><E><Q><A><S><H><L><G><G><A><V><F><S><G><A><G><N><I><A><A><A><T><G><L><V><K><R><E><E><F><P><T><D><L><K><P><E><E><V><A><Q><E><A><A><E><E><P><L... | Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by ... | Q16143 |
Q9HA64 | KT3K_HUMAN | Protein-psicosamine 3-kinase FN3KRP | Homo | <M><E><E><L><L><R><R><E><L><G><C><S><S><V><R><A><T><G><H><S><G><G><G><C><I><S><Q><G><R><S><Y><D><T><D><Q><G><R><V><F><V><K><V><N><P><K><A><E><A><R><R><M><F><E><G><E><M><A><S><L><T><A><I><L><K><T><N><T><V><K><V><P><K><P><I><K><V><L><D><A><P><G><G><G><S><V><L><V><M><E><H><M><D><M><R><H><L><S><S><H><A><A><K><L><G><A><Q><L... | Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively . Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose unde... | Q9HA64 |
P49238 | CX3C1_HUMAN | V28 | Homo | <M><D><Q><F><P><E><S><V><T><E><N><F><E><Y><D><D><L><A><E><A><C><Y><I><G><D><I><V><V><F><G><T><V><F><L><S><I><F><Y><S><V><I><F><A><I><G><L><V><G><N><L><L><V><V><F><A><L><T><N><S><K><K><P><K><S><V><T><D><I><Y><L><L><N><L><A><L><S><D><L><L><F><V><A><T><L><P><F><W><T><H><Y><L><I><N><E><K><G><L><H><N><A><M><C><K><F><T><T><A... | (Microbial infection) Acts as coreceptor with CD4 for HIV-1 virus envelope protein . May have more potent HIV-1 coreceptor activity than isoform 1 .<BOP> | P49238 |
P42166 | LAP2A_HUMAN | TP5 | Homo | <M><P><E><F><L><E><D><P><S><V><L><T><K><D><K><L><K><S><E><L><V><A><N><N><V><T><L><P><A><G><E><Q><R><K><D><V><Y><V><Q><L><Y><L><Q><H><L><T><A><R><N><R><P><P><L><P><A><G><T><N><S><K><G><P><P><D><F><S><S><D><E><E><R><E><P><T><P><V><L><G><S><G><A><A><A><A><G><R><S><R><A><A><V><G><R><K><A><T><K><K><T><D><K><P><R><Q><E><D><K... | TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.<BOP> | P42166 |
Q9GZR5 | ELOV4_HUMAN | Very long chain 3-oxoacyl-CoA synthase 4 | Homo | <M><G><L><L><D><S><E><P><G><S><V><L><N><V><V><S><T><A><L><N><D><T><V><E><F><Y><R><W><T><W><S><I><A><D><K><R><V><E><N><W><P><L><M><Q><S><P><W><P><T><L><S><I><S><T><L><Y><L><L><F><V><W><L><G><P><K><W><M><K><D><R><E><P><F><Q><M><R><L><V><L><I><I><Y><N><F><G><M><V><L><L><N><L><F><I><F><R><E><L><F><M><G><S><Y><N><A><G><Y><S... | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes... | Q9GZR5 |
Q8NBT2 | SPC24_HUMAN | Kinetochore protein Spc24 | Homo | <M><A><A><F><R><D><I><E><E><V><S><Q><G><L><L><S><L><L><G><A><N><R><A><E><A><Q><Q><R><R><L><L><G><R><H><E><Q><V><V><E><R><L><L><E><T><Q><D><G><A><E><K><Q><L><R><E><I><L><T><M><E><K><E><V><A><Q><S><L><L><N><A><K><E><Q><V><H><Q><G><G><V><E><L><Q><Q><L><E><A><G><L><Q><E><A><G><E><E><D><T><R><L><K><A><S><L><L><Q><L><T><R><E... | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity . Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore . The NDC80 complex synergistically ... | Q8NBT2 |
P01762 | HV311_HUMAN | Ig heavy chain V-III region TRO | Homo | <M><E><F><G><L><S><W><V><F><L><V><A><I><I><K><G><V><Q><C><Q><V><Q><L><V><E><S><G><G><G><L><V><K><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><S><D><Y><Y><M><S><W><I><R><Q><A><P><G><K><G><L><E><W><V><S><Y><I><S><S><S><S><S><Y><T><N><Y><A><D><S><V><K><G><R><F><T><I><S><R><D><N><A><K><N><S><L><Y><L><Q><M><N><S><L><R><A... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01762 |
P11233 | RALA_HUMAN | Ras-related protein Ral-A | Homo | <M><A><A><N><K><P><K><G><Q><N><S><L><A><L><H><K><V><I><M><V><G><S><G><G><V><G><K><S><A><L><T><L><Q><F><M><Y><D><E><F><V><E><D><Y><E><P><T><K><A><D><S><Y><R><K><K><V><V><L><D><G><E><E><V><Q><I><D><I><L><D><T><A><G><Q><E><D><Y><A><A><I><R><D><N><Y><F><R><S><G><E><G><F><L><C><V><F><S><I><T><E><M><E><S><F><A><A><T><A><D><F... | Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors . Acts as a GTP sensor for GTP-dependent exocytosis o... | P11233 |
P63167 | DYL1_HUMAN | Protein inhibitor of neuronal nitric oxide synthase | Homo | <M><C><D><R><K><A><V><I><K><N><A><D><M><S><E><E><M><Q><Q><D><S><V><E><C><A><T><Q><A><L><E><K><Y><N><I><E><K><D><I><A><A><H><I><K><K><E><F><D><K><K><Y><N><P><T><W><H><C><I><V><G><R><N><F><G><S><Y><V><T><H><E><T><K><H><F><I><Y><F><Y><L><G><Q><V><A><I><L><L><F><K><S><G> | Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.<BOP> | P63167 |
P49788 | TIG1_HUMAN | Tazarotene-induced gene 1 protein | Homo | <M><Q><P><R><R><Q><R><L><P><A><P><W><S><G><P><R><G><P><R><P><T><A><P><L><L><A><L><L><L><L><L><A><P><V><A><A><P><A><G><S><G><D><P><D><D><P><G><Q><P><Q><D><A><G><V><P><R><R><L><L><Q><Q><A><A><R><A><A><L><H><F><F><N><F><R><S><G><S><P><S><A><L><R><V><L><A><E><V><Q><E><G><R><A><W><I><N><P><K><E><G><C><K><V><H><V><V><F><S><T... | Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle.<BOP> | P49788 |
O96024 | B3GT4_HUMAN | UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase | Homo | <M><Q><L><R><L><F><R><R><L><L><L><A><A><L><L><L><V><I><V><W><T><L><F><G><P><S><G><L><G><E><E><L><L><S><L><S><L><A><S><L><L><P><A><P><A><S><P><G><P><P><L><A><L><P><R><L><L><I><P><N><Q><E><A><C><S><G><P><G><A><P><P><F><L><L><I><L><V><C><T><A><P><E><N><L><N><Q><R><N><A><I><R><A><S><W><G><G><L><R><E><A><R><G><L><R><V><Q><T... | Involved in GM1/GD1B/GA1 ganglioside biosynthesis.<BOP> | O96024 |
Q14CZ8 | HECAM_HUMAN | Hepatocyte cell adhesion molecule | Homo | <M><K><R><E><R><G><A><L><S><R><A><S><R><A><L><R><L><A><P><F><V><Y><L><L><L><I><Q><T><D><P><L><E><G><V><N><I><T><S><P><V><R><L><I><H><G><T><V><G><K><S><A><L><L><S><V><Q><Y><S><S><T><S><S><D><R><P><V><V><K><W><Q><L><K><R><D><K><P><V><T><V><V><Q><S><I><G><T><E><V><I><G><T><L><R><P><D><Y><R><D><R><I><R><L><F><E><N><G><S><L... | Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.<BOP> | Q14CZ8 |
Q99500 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor Edg-3 | Homo | <M><A><T><A><L><P><P><R><L><Q><P><V><R><G><N><E><T><L><R><E><H><Y><Q><Y><V><G><K><L><A><G><R><L><K><E><A><S><E><G><S><T><L><T><T><V><L><F><L><V><I><C><S><F><I><V><L><E><N><L><M><V><L><I><A><I><W><K><N><N><K><F><H><N><R><M><Y><F><F><I><G><N><L><A><L><C><D><L><L><A><G><I><A><Y><K><V><N><I><L><M><S><G><K><K><T><F><S><L><S... | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.<BOP> | Q99500 |
Q06141 | REG3A_HUMAN | Regenerating islet-derived protein 3-alpha 15 kDa form | Homo | <M><L><P><P><M><A><L><P><S><V><S><W><M><L><L><S><C><L><M><L><L><S><Q><V><Q><G><E><E><P><Q><R><E><L><P><S><A><R><I><R><C><P><K><G><S><K><A><Y><G><S><H><C><Y><A><L><F><L><S><P><K><S><W><T><D><A><D><L><A><C><Q><K><R><P><S><G><N><L><V><S><V><L><S><G><A><E><G><S><F><V><S><S><L><V><K><S><I><G><N><S><Y><S><Y><V><W><I><G><L><H... | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.<BOP> | Q06141 |
Q9NPB1 | NT5M_HUMAN | Deoxy-5'-nucleotidase 2 | Homo | <M><I><R><L><G><G><W><C><A><R><R><L><C><S><A><A><V><P><A><G><R><R><G><A><A><G><G><L><G><L><A><G><G><R><A><L><R><V><L><V><D><M><D><G><V><L><A><D><F><E><G><G><F><L><R><K><F><R><A><R><F><P><D><Q><P><F><I><A><L><E><D><R><R><G><F><W><V><S><E><Q><Y><G><R><L><R><P><G><L><S><E><K><A><I><S><I><W><E><S><K><N><F><F><F><E><L><E><P... | Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.<BOP> | Q9NPB1 |
Q562R1 | ACTBL_HUMAN | Kappa-actin | Homo | <M><T><D><N><E><L><S><A><L><V><V><D><N><G><S><G><M><C><K><A><G><F><G><G><D><D><A><P><R><A><V><F><P><S><M><I><G><R><P><R><H><Q><G><V><M><V><G><M><G><Q><K><D><C><Y><V><G><D><E><A><Q><S><K><R><G><V><L><T><L><K><Y><P><I><E><H><G><V><V><T><N><W><D><D><M><E><K><I><W><Y><H><T><F><Y><N><E><L><R><V><A><P><D><E><H><P><I><L><L><T... | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.<BOP> | Q562R1 |
P25024 | CXCR1_HUMAN | IL-8 receptor type 1 | Homo | <M><S><N><I><T><D><P><Q><M><W><D><F><D><D><L><N><F><T><G><M><P><P><A><D><E><D><Y><S><P><C><M><L><E><T><E><T><L><N><K><Y><V><V><I><I><A><Y><A><L><V><F><L><L><S><L><L><G><N><S><L><V><M><L><V><I><L><Y><S><R><V><G><R><S><V><T><D><V><Y><L><L><N><L><A><L><A><D><L><L><F><A><L><T><L><P><I><W><A><A><S><K><V><N><G><W><I><F><G><T... | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor . Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system .<BOP> | P25024 |
Q9P1P5 | TAAR2_HUMAN | G-protein coupled receptor 58 | Homo | <M><A><V><S><S><E><Q><H><E><L><S><H><F><K><R><T><Q><T><K><K><E><K><F><N><C><S><E><Y><G><N><R><S><C><P><E><N><E><R><S><L><G><V><R><V><A><M><Y><S><F><M><A><G><S><I><F><I><T><I><F><G><N><L><A><M><I><I><S><I><S><Y><F><K><Q><L><H><T><P><T><N><F><L><I><L><S><M><A><I><T><D><F><L><L><G><F><T><I><M><P><Y><S><M><I><R><S><V><E><N... | Orphan receptor.<BOP> | Q9P1P5 |
P49640 | EVX1_HUMAN | EVX-1 | Homo | <M><E><S><R><K><D><M><V><V><F><L><D><G><G><Q><L><G><T><L><V><G><K><R><V><S><N><L><S><E><A><V><G><S><P><L><P><E><P><P><E><K><M><V><P><R><G><C><L><S><P><R><A><V><P><P><A><T><R><E><R><G><G><G><G><P><E><E><E><P><V><D><G><L><A><G><S><A><A><G><P><G><A><E><P><Q><V><A><G><A><A><M><L><G><P><G><P><P><A><P><S><V><D><S><L><S><G><Q... | May play a role in the specification of neuronal cell types.<BOP> | P49640 |
P48065 | S6A12_HUMAN | Solute carrier family 6 member 12 | Homo | <M><D><G><K><V><A><V><Q><E><C><G><P><P><A><V><S><W><V><P><E><E><G><E><K><L><D><Q><E><D><E><D><Q><V><K><D><R><G><Q><W><T><N><K><M><E><F><V><L><S><V><A><G><E><I><I><G><L><G><N><V><W><R><F><P><Y><L><C><Y><K><N><G><G><G><A><F><F><I><P><Y><F><I><F><F><F><V><C><G><I><P><V><F><F><L><E><V><A><L><G><Q><Y><T><S><Q><G><S><V><T><A... | Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.<BOP> | P48065 |
Q01860 | PO5F1_HUMAN | Octamer-binding transcription factor 3 | Homo | <M><A><G><H><L><A><S><D><F><A><F><S><P><P><P><G><G><G><G><D><G><P><G><G><P><E><P><G><W><V><D><P><R><T><W><L><S><F><Q><G><P><P><G><G><P><G><I><G><P><G><V><G><P><G><S><E><V><W><G><I><P><P><C><P><P><P><Y><E><F><C><G><G><M><A><Y><C><G><P><Q><V><G><V><G><L><V><P><Q><G><G><L><E><T><S><Q><P><E><G><E><A><G><V><G><V><E><S><N><S... | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<BOP... | Q01860 |
Q9H720 | PG2IP_HUMAN | Cell wall biogenesis protein 43 C-terminal homolog | Homo | <M><P><S><L><W><R><E><I><L><L><E><S><L><L><G><C><V><S><W><S><L><Y><H><D><L><G><P><M><I><Y><Y><F><P><L><Q><T><L><E><L><T><G><L><E><G><F><S><I><A><F><L><S><P><I><F><L><T><I><T><P><F><W><K><L><V><N><K><K><W><M><L><T><L><L><R><I><I><T><I><G><S><I><A><S><F><Q><A><P><N><A><K><L><R><L><M><V><L><A><L><G><V><S><S><S><L><I><V><Q... | Involved in lipid remodeling during GPI-anchor maturation.<BOP> | Q9H720 |
Q9H6B9 | EPHX3_HUMAN | Abhydrolase domain-containing protein 9 | Homo | <M><P><E><L><V><V><T><A><L><L><A><P><S><R><L><S><L><K><L><L><R><A><F><M><W><S><L><V><F><S><V><A><L><V><A><A><A><V><Y><G><C><I><A><L><T><H><V><L><C><R><P><R><R><G><C><C><G><R><R><R><S><A><S><P><A><C><L><S><D><P><S><L><G><E><H><G><F><L><N><L><K><S><S><G><L><R><L><H><Y><V><S><A><G><R><G><N><G><P><L><M><L><F><L><H><G><F><P... | Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin.<BOP> | Q9H6B9 |
Q9NS82 | AAA1_HUMAN | Solute carrier family 7 member 10 | Homo | <M><A><G><H><T><Q><Q><P><S><G><R><G><N><P><R><P><A><P><S><P><S><P><V><P><G><T><V><P><G><A><S><E><R><V><A><L><K><K><E><I><G><L><L><S><A><C><T><I><I><I><G><N><I><I><G><S><G><I><F><I><S><P><K><G><V><L><E><H><S><G><S><V><G><L><A><L><F><V><W><V><L><G><G><G><V><T><A><L><G><S><L><C><Y><A><E><L><G><V><A><I><P><K><S><G><G><D><Y... | Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse.<BOP> | Q9NS82 |
O95391 | SLU7_HUMAN | Pre-mRNA-splicing factor SLU7 | Homo | <M><S><A><T><V><V><D><A><V><N><A><A><P><L><S><G><S><K><E><M><S><L><E><E><P><K><K><M><T><R><E><D><W><R><K><K><K><E><L><E><E><Q><R><K><L><G><N><A><P><A><E><V><D><E><E><G><K><D><I><N><P><H><I><P><Q><Y><I><S><S><V><P><W><Y><I><D><P><S><K><R><P><T><L><K><H><Q><R><P><Q><P><E><K><Q><K><Q><F><S><S><S><G><E><W><Y><K><R><G><V><K... | Required for pre-mRNA splicing as component of the spliceosome . Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for corre... | O95391 |
Q969J2 | ZKSC4_HUMAN | Zinc finger protein 427 | Homo | <M><A><R><E><P><R><K><N><A><A><L><D><A><Q><S><A><E><D><Q><T><G><L><L><T><V><K><V><E><K><E><E><A><S><A><L><T><A><E><V><R><A><P><C><S><P><A><R><G><P><E><R><S><R><Q><R><F><R><G><F><R><Y><P><E><A><A><G><P><R><E><A><L><S><R><L><R><E><L><C><G><Q><W><L><Q><P><E><M><H><S><K><E><Q><I><L><E><L><L><V><L><E><Q><F><L><T><I><L><P><G... | May be involved in the transcriptional activation of MDM2 and EP300 genes.<BOP> | Q969J2 |
Q15544 | TAF11_HUMAN | Transcription initiation factor TFIID 28 kDa subunit | Homo | <M><D><D><A><H><E><S><P><S><D><K><G><G><E><T><G><E><S><D><E><T><A><A><V><P><G><D><P><G><A><T><D><T><D><G><I><P><E><E><T><D><G><D><A><D><V><D><L><K><E><A><A><A><E><E><G><E><L><E><S><Q><D><V><S><D><L><T><T><V><E><R><E><D><S><S><L><L><N><P><A><A><K><K><L><K><I><D><T><K><E><K><K><E><K><K><Q><K><V><D><E><D><E><I><Q><K><M><Q... | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription . TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) . The TFIID... | Q15544 |
Q70EK9 | UBP51_HUMAN | Ubiquitin-specific-processing protease 51 | Homo | <M><A><Q><V><R><E><T><S><L><P><S><G><S><G><V><R><W><I><S><G><G><G><G><G><A><S><P><E><E><A><V><E><K><A><G><K><M><E><E><A><A><A><G><A><T><K><A><S><S><R><R><E><A><E><E><M><K><L><E><P><L><Q><E><R><E><P><A><P><E><E><N><L><T><W><S><S><S><G><G><D><E><K><V><L><P><S><I><P><L><R><C><H><S><S><S><S><P><V><C><P><R><R><K><P><R><P><R... | Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) . USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'... | Q70EK9 |
Q08117 | TLE5_HUMAN | TLE family member 5, transcriptional modulator | Homo | <M><M><F><P><Q><S><R><H><S><G><S><S><H><L><P><Q><Q><L><K><F><T><T><S><D><S><C><D><R><I><K><D><E><F><Q><L><L><Q><A><Q><Y><H><S><L><K><L><E><C><D><K><L><A><S><E><K><S><E><M><Q><R><H><Y><V><M><Y><Y><E><M><S><Y><G><L><N><I><E><M><H><K><Q><A><E><I><V><K><R><L><N><G><I><C><A><Q><V><L><P><Y><L><S><Q><E><H><Q><Q><Q><V><L><G><A... | Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.<BOP> | Q08117 |
Q5XKP0 | MIC13_HUMAN | Protein P117 | Homo | <M><V><A><R><V><W><S><L><M><R><F><L><I><K><G><S><V><A><G><G><A><V><Y><L><V><Y><D><Q><E><L><L><G><P><S><D><K><S><Q><A><A><L><Q><K><A><G><E><V><V><P><P><A><M><Y><Q><F><S><Q><Y><V><C><Q><Q><T><G><L><Q><I><P><Q><L><P><A><P><P><K><I><Y><F><P><I><R><D><S><W><N><A><G><I><M><T><V><M><S><A><L><S><V><A><P><S><K><A><R><E><Y><S><K... | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae... | Q5XKP0 |
Q9BTD8 | RBM42_HUMAN | RNA-binding motif protein 42 | Homo | <M><A><G><A><G><P><A><P><G><L><P><G><A><G><G><P><V><V><P><G><P><G><A><G><I><P><G><K><S><G><E><E><R><L><K><E><M><E><A><E><M><A><L><F><E><Q><E><V><L><G><A><P><V><P><G><I><P><T><A><V><P><A><V><P><T><V><P><T><V><P><T><V><E><A><M><Q><V><P><A><A><P><V><I><R><P><I><I><A><T><N><T><Y><Q><Q><V><Q><Q><T><L><E><A><R><A><A><A><A><A... | Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.<BOP> | Q9BTD8 |
Q04743 | EMX2_HUMAN | Empty spiracles-like protein 2 | Homo | <M><F><Q><P><A><P><K><R><C><F><T><I><E><S><L><V><A><K><D><S><P><L><P><A><S><R><S><E><D><P><I><R><P><A><A><L><S><Y><A><N><S><S><P><I><N><P><F><L><N><G><F><H><S><A><A><A><A><A><A><G><R><G><V><Y><S><N><P><D><L><V><F><A><E><A><V><S><H><P><P><N><P><A><V><P><V><H><P><V><P><P><P><H><A><L><A><A><H><P><L><P><S><S><H><S><P><H><P... | Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.<BOP> | Q04743 |
Q11203 | SIAT6_HUMAN | Sialyltransferase 6 | Homo | <M><G><L><L><V><F><V><R><N><L><L><L><A><L><C><L><F><L><V><L><G><F><L><Y><Y><S><A><W><K><L><H><L><L><Q><W><E><E><D><S><N><S><V><V><L><S><F><D><S><A><G><Q><T><L><G><S><E><Y><D><R><L><G><F><L><L><N><L><D><S><K><L><P><A><E><L><A><T><K><Y><A><N><F><S><E><G><A><C><K><P><G><Y><A><S><A><L><M><T><A><I><F><P><R><F><S><K><P><A><P... | Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNA... | Q11203 |
P12318 | FCG2A_HUMAN | Fc-gamma RII-a | Homo | <M><T><M><E><T><Q><M><S><Q><N><V><C><P><R><N><L><W><L><L><Q><P><L><T><V><L><L><L><L><A><S><A><D><S><Q><A><A><A><P><P><K><A><V><L><K><L><E><P><P><W><I><N><V><L><Q><E><D><S><V><T><L><T><C><Q><G><A><R><S><P><E><S><D><S><I><Q><W><F><H><N><G><N><L><I><P><T><H><T><Q><P><S><Y><R><F><K><A><N><N><N><D><S><G><E><Y><T><C><Q><T><G... | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.<BOP> | P12318 |
O95972 | BMP15_HUMAN | Growth/differentiation factor 9B | Homo | <M><V><L><L><S><I><L><R><I><L><F><L><C><E><L><V><L><F><M><E><H><R><A><Q><M><A><E><G><G><Q><S><S><I><A><L><L><A><E><A><P><T><L><P><L><I><E><E><L><L><E><E><S><P><G><E><Q><P><R><K><P><R><L><L><G><H><S><L><R><Y><M><L><E><L><Y><R><R><S><A><D><S><H><G><H><P><R><E><N><R><T><I><G><A><T><M><V><R><L><V><K><P><L><T><N><V><A><R><P... | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.<BOP> | O95972 |
Q9BSG0 | PADC1_HUMAN | Protease-associated domain-containing protein of 21 kDa | Homo | <M><V><P><G><A><A><G><W><C><C><L><V><L><W><L><P><A><C><V><A><A><H><G><F><R><I><H><D><Y><L><Y><F><Q><V><L><S><P><G><D><I><R><Y><I><F><T><A><T><P><A><K><D><F><G><G><I><F><H><T><R><Y><E><Q><I><H><L><V><P><A><E><P><P><E><A><C><G><E><L><S><N><G><F><F><I><Q><D><Q><I><A><L><V><E><R><G><G><C><S><F><L><S><K><T><R><V><V><Q><E><H... | Plays a role in the modulation of physical activity and adiposity.<BOP> | Q9BSG0 |
P33261 | CP2CJ_HUMAN | Mephenytoin 4-hydroxylase | Homo | <M><D><P><F><V><V><L><V><L><C><L><S><C><L><L><L><L><S><I><W><R><Q><S><S><G><R><G><K><L><P><P><G><P><T><P><L><P><V><I><G><N><I><L><Q><I><D><I><K><D><V><S><K><S><L><T><N><L><S><K><I><Y><G><P><V><F><T><L><Y><F><G><L><E><R><M><V><V><L><H><G><Y><E><V><V><K><E><A><L><I><D><L><G><E><E><F><S><G><R><G><H><F><P><L><A><E><R><A><N... | A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein redu... | P33261 |
Q8N6M8 | IQCF1_HUMAN | IQ domain-containing protein F1 | Homo | <M><E><E><K><Q><P><Q><K><T><K><E><P><S><K><E><D><E><P><Q><Q><K><E><M><P><T><H><L><S><L><G><A><E><S><K><A><E><A><K><T><P><V><L><V><E><T><Q><T><V><D><N><A><N><E><K><S><E><K><P><P><E><N><Q><K><K><L><S><D><K><D><T><V><A><T><K><I><Q><A><W><W><R><G><T><L><V><R><R><A><L><L><H><A><A><L><S><A><C><I><I><Q><C><W><W><R><L><I><L><S... | Involved in sperm capacitation and acrosome reaction.<BOP> | Q8N6M8 |
Q14457 | BECN1_HUMAN | Beclin-1-C 37 kDa | Homo | <M><E><G><S><K><T><S><N><N><S><T><M><Q><V><S><F><V><C><Q><R><C><S><Q><P><L><K><L><D><T><S><F><K><I><L><D><R><V><T><I><Q><E><L><T><A><P><L><L><T><T><A><Q><A><K><P><G><E><T><Q><E><E><E><T><N><S><G><E><E><P><F><I><E><T><P><R><Q><D><G><V><S><R><R><F><I><P><P><A><R><M><M><S><T><E><S><A><N><S><F><T><L><I><G><E><A><S><D><G><G... | Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.<BOP> | Q14457 |
P17568 | NDUB7_HUMAN | NADH-ubiquinone oxidoreductase B18 subunit | Homo | <M><G><A><H><L><V><R><R><Y><L><G><D><A><S><V><E><P><D><P><L><Q><M><P><T><F><P><P><D><Y><G><F><P><E><R><K><E><R><E><M><V><A><T><Q><Q><E><M><M><D><A><Q><L><R><L><Q><L><R><D><Y><C><A><H><H><L><I><R><L><L><K><C><K><R><D><S><F><P><N><F><L><A><C><K><Q><E><R><H><D><W><D><Y><C><E><H><R><D><Y><V><M><R><M><K><E><F><E><R><E><R><R... | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP> | P17568 |
Q7Z429 | LFG1_HUMAN | Transmembrane BAX inhibitor motif-containing protein 3 | Homo | <M><S><H><E><K><S><F><L><V><S><G><D><N><Y><P><P><P><N><P><G><Y><P><G><G><P><Q><P><P><M><P><P><Y><A><Q><P><P><Y><P><G><A><P><Y><P><Q><P><P><F><Q><P><S><P><Y><G><Q><P><G><Y><P><H><G><P><S><P><Y><P><Q><G><G><Y><P><Q><G><P><Y><P><Q><G><G><Y><P><Q><G><P><Y><P><Q><E><G><Y><P><Q><G><P><Y><P><Q><G><G><Y><P><Q><G><P><Y><P><Q><S... | Potential apoptotic regulator.<BOP> | Q7Z429 |
P59922 | OR2B8_HUMAN | Hs6M1-29P | Homo | <M><D><Q><K><N><G><S><S><F><T><G><F><I><L><L><G><F><S><D><R><P><Q><L><E><L><V><L><F><V><V><L><L><I><F><Y><I><F><T><L><L><G><N><K><T><I><I><V><L><S><H><L><D><P><H><L><H><T><P><M><Y><F><F><F><S><N><L><S><F><L><D><L><C><Y><T><T><G><I><V><P><Q><L><L><V><N><L><R><G><A><D><K><S><I><S><Y><G><G><C><V><V><Q><L><Y><I><S><L><G><L... | Odorant receptor.<BOP> | P59922 |
P41238 | ABEC1_HUMAN | mRNA(cytosine(6666)) deaminase 1 | Homo | <M><T><S><E><K><G><P><S><T><G><D><P><T><L><R><R><R><I><E><P><W><E><F><D><V><F><Y><D><P><R><E><L><R><K><E><A><C><L><L><Y><E><I><K><W><G><M><S><R><K><I><W><R><S><S><G><K><N><T><T><N><H><V><E><V><N><F><I><K><K><F><T><S><E><R><D><F><H><P><S><M><S><C><S><I><T><W><F><L><S><W><S><P><C><W><E><C><S><Q><A><I><R><E><F><L><S><R><H... | Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene exp... | P41238 |
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