accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q9Y255 | PRLD1_HUMAN | Px19-like protein | Homo | <M><V><K><Y><F><L><G><Q><S><V><L><R><S><S><W><D><Q><V><F><A><A><F><W><Q><R><Y><P><N><P><Y><S><K><H><V><L><T><E><D><I><V><H><R><E><V><T><P><D><Q><K><L><L><S><R><R><L><L><T><K><T><N><R><M><P><R><W><A><E><R><L><F><P><A><N><V><A><H><S><V><Y><V><L><E><D><S><I><V><D><P><Q><N><Q><T><M><T><T><F><T><W><N><I><N><H><A><R><L><M><V... | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion interm... | Q9Y255 |
Q9P0W2 | HM20B_HUMAN | Structural DNA-binding protein BRAF35 | Homo | <M><S><H><G><P><K><Q><P><G><A><A><A><A><P><A><G><G><K><A><P><G><Q><H><G><G><F><V><V><T><V><K><Q><E><R><G><E><G><P><R><A><G><E><K><G><S><H><E><E><E><P><V><K><K><R><G><W><P><K><G><K><K><R><K><K><I><L><P><N><G><P><K><A><P><V><T><G><Y><V><R><F><L><N><E><R><R><E><Q><I><R><T><R><H><P><D><L><P><F><P><E><I><T><K><M><L><G><A><E... | Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.<BOP> | Q9P0W2 |
Q9H1Z9 | TSN10_HUMAN | Oculospanin | Homo | <M><E><E><G><E><R><S><P><L><L><S><Q><E><T><A><G><Q><K><P><L><S><V><H><R><P><P><T><S><G><C><L><G><P><V><P><R><E><D><Q><A><E><A><W><G><C><S><C><C><P><P><E><T><K><H><Q><A><L><S><G><T><P><K><K><G><P><A><P><S><L><S><P><G><S><S><C><V><K><Y><L><I><F><L><S><N><F><P><F><S><L><L><G><L><L><A><L><A><I><G><L><W><G><L><A><V><K><G><S... | Regulates maturation of the transmembrane metalloprotease ADAM10.<BOP> | Q9H1Z9 |
Q6UWW8 | EST3_HUMAN | Liver carboxylesterase 31 homolog | Homo | <M><E><R><A><V><R><V><E><S><G><V><L><V><G><V><V><C><L><L><L><A><C><P><A><T><A><T><G><P><E><V><A><Q><P><E><V><D><T><T><L><G><R><V><R><G><R><Q><V><G><V><K><G><T><D><R><L><V><N><V><F><L><G><I><P><F><A><Q><P><P><L><G><P><D><R><F><S><A><P><H><P><A><Q><P><W><E><G><V><R><D><A><S><T><A><P><P><M><C><L><Q><D><V><E><S><M><N><S><S... | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.<BOP> | Q6UWW8 |
P49821 | NDUV1_HUMAN | NADH-ubiquinone oxidoreductase 51 kDa subunit | Homo | <M><L><A><T><R><R><L><L><G><W><S><L><P><A><R><V><S><V><R><F><S><G><D><T><T><A><P><K><K><T><S><F><G><S><L><K><D><E><D><R><I><F><T><N><L><Y><G><R><H><D><W><R><L><K><G><S><L><S><R><G><D><W><Y><K><T><K><E><I><L><L><K><G><P><D><W><I><L><G><E><I><K><T><S><G><L><R><G><R><G><G><A><G><F><P><T><G><L><K><W><S><F><M><N><K><P><S><D... | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.<BOP> | P49821 |
Q96EY7 | PTCD3_HUMAN | Transformation-related gene 15 protein | Homo | <M><A><V><V><S><A><V><R><W><L><G><L><R><S><R><L><G><Q><P><L><T><G><R><R><A><G><L><C><E><Q><A><R><S><C><R><F><Y><S><G><S><A><T><L><S><K><V><E><G><T><D><V><T><G><I><E><E><V><V><I><P><K><K><K><T><W><D><K><V><A><V><L><Q><A><L><A><S><T><V><N><R><D><T><T><A><V><P><Y><V><F><Q><D><D><P><Y><L><M><P><A><S><S><L><E><S><R><S><F><L... | Mitochondrial RNA-binding protein that has a role in mitochondrial translation.<BOP> | Q96EY7 |
Q8TBZ5 | ZN502_HUMAN | Zinc finger protein 502 | Homo | <M><L><N><M><Q><G><A><E><E><R><D><I><R><R><E><T><C><P><G><W><V><N><K><N><K><P><A><L><E><Q><D><V><C><K><I><D><S><S><G><I><V><V><K><R><F><Q><E><D><E><Y><Q><D><S><T><F><E><E><K><Y><A><C><E><G><M><K><E><N><S><P><R><E><I><A><E><S><C><L><F><Q><E><G><G><F><G><R><I><T><F><I><H><K><E><A><P><P><E><I><I><S><Q><G><Y><N><F><E><K><S... | May be involved in transcriptional regulation.<BOP> | Q8TBZ5 |
Q9Y2X8 | UB2D4_HUMAN | Ubiquitin-protein ligase D4 | Homo | <M><A><L><K><R><I><Q><K><E><L><T><D><L><Q><R><D><P><P><A><Q><C><S><A><G><P><V><G><D><D><L><F><H><W><Q><A><T><I><M><G><P><N><D><S><P><Y><Q><G><G><V><F><F><L><T><I><H><F><P><T><D><Y><P><F><K><P><P><K><V><A><F><T><T><K><I><Y><H><P><N><I><N><S><N><G><S><I><C><L><D><I><L><R><S><Q><W><S><P><A><L><T><V><S><K><V><L><L><S><I><C... | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination.<BOP> | Q9Y2X8 |
Q8IXL7 | MSRB3_HUMAN | Methionine-R-sulfoxide reductase B3 | Homo | <M><S><P><R><R><T><L><P><R><P><L><S><L><C><L><S><L><C><L><C><L><C><L><A><A><A><L><G><S><A><Q><S><G><S><C><R><D><K><K><N><C><K><V><V><F><S><Q><Q><E><L><R><K><R><L><T><P><L><Q><Y><H><V><T><Q><E><K><G><T><E><S><A><F><E><G><E><Y><T><H><H><K><D><P><G><I><Y><K><C><V><V><C><G><T><P><L><F><K><S><E><T><K><F><D><S><G><S><G><W><P... | Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.<BOP> | Q8IXL7 |
Q06609 | RAD51_HUMAN | RAD51 homolog A | Homo | <M><A><M><Q><M><Q><L><E><A><N><A><D><T><S><V><E><E><E><S><F><G><P><Q><P><I><S><R><L><E><Q><C><G><I><N><A><N><D><V><K><K><L><E><E><A><G><F><H><T><V><E><A><V><A><Y><A><P><K><K><E><L><I><N><I><K><G><I><S><E><A><K><A><D><K><I><L><A><E><A><A><K><L><V><P><M><G><F><T><T><A><T><E><F><H><Q><R><R><S><E><I><I><Q><I><T><T><G><S><K... | Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) . Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange . Catalyzes the recognition of homology and stra... | Q06609 |
Q8N7C0 | LRC52_HUMAN | BK channel auxiliary gamma subunit LRRC52 | Homo | <M><S><L><A><S><G><P><G><P><G><W><L><L><F><S><F><G><M><G><L><V><S><G><S><K><C><P><N><N><C><L><C><Q><A><Q><E><V><I><C><T><G><K><Q><L><T><E><Y><P><L><D><I><P><L><N><T><R><R><L><F><L><N><E><N><R><I><T><S><L><P><A><M><H><L><G><L><L><S><D><L><V><Y><L><D><C><Q><N><N><R><I><R><E><V><M><D><Y><T><F><I><G><V><F><K><L><I><Y><L><D... | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modul... | Q8N7C0 |
Q9H4L4 | SENP3_HUMAN | Sentrin/SUMO-specific protease SENP3 | Homo | <M><K><E><T><I><Q><G><T><G><S><W><G><P><E><P><P><G><P><G><I><P><P><A><Y><S><S><P><R><R><E><R><L><R><W><P><P><P><P><K><P><R><L><K><S><G><G><G><F><G><P><D><P><G><S><G><T><T><V><P><A><R><R><L><P><V><P><R><P><S><F><D><A><S><A><S><E><E><E><E><E><E><E><E><E><E><D><E><D><E><E><E><E><V><A><A><W><R><L><P><P><R><W><S><Q><L><G><T... | Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates . Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability . Deconjugates SUMO2 and SUMO3 from CDCA8 . Redox sensor that, when redistributed into nucleoplasm, c... | Q9H4L4 |
Q6Y288 | B3GLT_HUMAN | Beta-3-glycosyltransferase-like | Homo | <M><R><P><P><A><C><W><W><L><L><A><P><P><A><L><L><A><L><L><T><C><S><L><A><F><G><L><A><S><E><D><T><K><K><E><V><K><Q><S><Q><D><L><E><K><S><G><I><S><R><K><N><D><I><D><L><K><G><I><V><F><V><I><Q><S><Q><S><N><S><F><H><A><K><R><A><E><Q><L><K><K><S><I><L><K><Q><A><A><D><L><T><Q><E><L><P><S><V><L><L><L><H><Q><L><A><K><Q><E><G><A... | O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.<BOP> | Q6Y288 |
P58215 | LOXL3_HUMAN | Lysyl oxidase-like protein 3 | Homo | <M><R><P><V><S><V><W><Q><W><S><P><W><G><L><L><L><C><L><L><C><S><S><C><L><G><S><P><S><P><S><T><G><P><E><K><K><A><G><S><Q><G><L><R><F><R><L><A><G><F><P><R><K><P><Y><E><G><R><V><E><I><Q><R><A><G><E><W><G><T><I><C><D><D><D><F><T><L><Q><A><A><H><I><L><C><R><E><L><G><F><T><E><A><T><G><W><T><H><S><A><K><Y><G><P><G><T><G><R><I... | Shows protein-lysine 6-oxidase activity toward elastin and different types of collagens, with the highest activity toward collagen type IV .<BOP> | P58215 |
P52306 | GDS1_HUMAN | SMG P21 stimulatory GDP/GTP exchange protein | Homo | <M><D><N><L><S><D><T><L><K><K><L><K><I><T><A><V><D><K><T><E><D><S><L><E><G><C><L><D><C><L><L><Q><A><L><A><Q><N><N><T><E><T><S><E><K><I><Q><A><S><G><I><L><Q><L><F><A><S><L><L><T><P><Q><S><S><C><K><A><K><V><A><N><I><I><A><E><V><A><K><N><E><F><M><R><I><P><C><V><D><A><G><L><I><S><P><L><V><Q><L><L><N><S><K><D><Q><E><V><L><L... | Acts as a GEF (guanine nucleotide exchange factor) for prenylated RHOA . Acts as a GEF for RHOC . Chaperones the downstream trafficking and/or processing of small newly prenylated GTPases . Escorts RAC1 to the nucleus .<BOP> | P52306 |
P18124 | RL7_HUMAN | Large ribosomal subunit protein uL30 | Homo | <M><E><G><V><E><E><K><K><K><E><V><P><A><V><P><E><T><L><K><K><K><R><R><N><F><A><E><L><K><I><K><R><L><R><K><K><F><A><Q><K><M><L><R><K><A><R><R><K><L><I><Y><E><K><A><K><H><Y><H><K><E><Y><R><Q><M><Y><R><T><E><I><R><M><A><R><M><A><R><K><A><G><N><F><Y><V><P><A><E><P><K><L><A><F><V><I><R><I><R><G><I><N><G><V><S><P><K><V><R><K... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell . Binds to G-rich structures in 28S rRNA and in mRNAs . Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs .<BOP> | P18124 |
Q6UXB2 | CXL17_HUMAN | 4-Cys CXCL17 | Homo | <M><K><V><L><I><S><S><L><L><L><L><L><P><L><M><L><M><S><M><V><S><S><S><L><N><P><G><V><A><R><G><H><R><D><R><G><Q><A><S><R><R><W><L><Q><E><G><G><Q><E><C><E><C><K><D><W><F><L><R><A><P><R><R><K><F><M><T><V><S><G><L><P><K><K><Q><C><P><C><D><H><F><K><G><N><V><K><K><T><R><H><Q><R><H><H><R><K><P><N><K><H><S><R><A><C><Q><Q><F><L... | Seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.<BOP> | Q6UXB2 |
A6NNS2 | DRS7C_HUMAN | Short-chain dehydrogenase/reductase family 32C member 2 | Homo | <M><G><V><M><A><M><L><M><L><P><L><L><L><L><G><I><S><G><L><L><F><I><Y><Q><E><V><S><R><L><W><S><K><S><A><V><Q><N><K><V><V><V><I><T><D><A><I><S><G><L><G><K><E><C><A><R><V><F><H><T><G><G><A><R><L><V><L><C><G><K><N><W><E><R><L><E><N><L><Y><D><A><L><I><S><V><A><D><P><S><K><Q><T><F><T><P><K><L><V><L><L><D><L><S><D><I><S><C><V... | NADH-dependent oxidoreductase which catalyzes the oxidation of all-trans-retinol to all-trans-retinal. Plays a role in the regulation of cardiac and skeletal muscle metabolic functions. Maintains Ca(2+) intracellular homeostasis by repressing Ca(2+) release from the sarcoplasmic reticulum (SR) in myotubes, possibly thr... | A6NNS2 |
Q5T0L3 | SPT46_HUMAN | Spermatogenesis-associated protein 46 | Homo | <M><E><N><F><S><L><L><S><I><S><G><P><P><I><S><S><S><A><L><S><A><F><P><D><I><M><F><S><R><A><T><S><L><P><D><I><A><K><T><A><V><P><T><E><A><S><S><P><A><Q><A><L><P><P><Q><Y><Q><S><I><I><V><R><Q><G><I><Q><N><T><A><L><S><P><D><C><S><L><G><D><T><Q><H><G><E><K><L><R><R><N><C><T><I><Y><R><P><W><F><S><P><Y><S><Y><F><V><C><A><D><K... | Plays a role in spermiogenesis and fertilization.<BOP> | Q5T0L3 |
Q13585 | MTR1L_HUMAN | H9 | Homo | <M><G><P><T><L><A><V><P><T><P><Y><G><C><I><G><C><K><L><P><Q><P><E><Y><P><P><A><L><I><I><F><M><F><C><A><M><V><I><T><I><V><V><D><L><I><G><N><S><M><V><I><L><A><V><T><K><N><K><K><L><R><N><S><G><N><I><F><V><V><S><L><S><V><A><D><M><L><V><A><I><Y><P><Y><P><L><M><L><H><A><M><S><I><G><G><W><D><L><S><Q><L><Q><C><Q><M><V><G><F><I... | Does not bind melatonin.<BOP> | Q13585 |
A8MWX3 | WASH4_HUMAN | Protein FAM39CP | Homo | <M><S><G><V><M><C><L><K><A><S><D><T><W><A><S><G><I><R><S><Q><P><Q><G><C><L><G><K><W><R><S><M><R><C><K><H><T><R><M><H><L><A><H><L><G><N><S><R><Q><L><I><S><L><G><P><P><R><T><R><E><D><G><S><R><I><S><Q><Q><V><E><Q><S><R><S><Q><V><Q><A><I><G><E><K><V><S><L><A><Q><A><K><I><E><K><I><K><G><S><K><K><A><I><K><V><F><S><S><A><K><Y... | May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.<BOP> | A8MWX3 |
Q9BY43 | CHM4A_HUMAN | Vacuolar protein sorting-associated protein 32-1 | Homo | <M><S><G><L><G><R><L><F><G><K><G><K><K><E><K><G><P><T><P><E><E><A><I><Q><K><L><K><E><T><E><K><I><L><I><K><K><Q><E><F><L><E><Q><K><I><Q><Q><E><L><Q><T><A><K><K><Y><G><T><K><N><K><R><A><A><L><Q><A><L><R><R><K><K><R><F><E><Q><Q><L><A><Q><T><D><G><T><L><S><T><L><E><F><Q><R><E><A><I><E><N><A><T><T><N><A><E><V><L><R><T><M><E... | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membr... | Q9BY43 |
P20933 | ASPG_HUMAN | Glycosylasparaginase beta chain | Homo | <M><A><R><K><S><N><L><P><V><L><L><V><P><F><L><L><C><Q><A><L><V><R><C><S><S><P><L><P><L><V><V><N><T><W><P><F><K><N><A><T><E><A><A><W><R><A><L><A><S><G><G><S><A><L><D><A><V><E><S><G><C><A><M><C><E><R><E><Q><C><D><G><S><V><G><F><G><G><S><P><D><E><L><G><E><T><T><L><D><A><M><I><M><D><G><T><T><M><D><V><G><A><V><G><D><L><R><R... | Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.<BOP> | P20933 |
Q8NGI3 | O56B1_HUMAN | Olfactory receptor OR11-65 | Homo | <M><N><H><M><S><A><S><L><K><I><S><N><S><S><K><F><Q><V><S><E><F><I><L><L><G><F><P><G><I><H><S><W><Q><H><W><L><S><L><P><L><A><L><L><Y><L><S><A><L><A><A><N><T><L><I><L><I><I><I><W><Q><N><P><S><L><Q><Q><P><M><Y><I><F><L><G><I><L><C><M><V><D><M><G><L><A><T><T><I><I><P><K><I><L><A><I><F><W><F><D><A><K><V><I><S><L><P><E><C><F... | Odorant receptor.<BOP> | Q8NGI3 |
Q8WV83 | S35F5_HUMAN | Hepatitis C virus NS5A-transactivated protein 3 | Homo | <M><V><P><P><R><R><H><R><G><A><G><R><P><G><V><L><S><S><S><P><P><F><R><L><R><S><A><K><F><S><G><I><A><L><E><D><L><R><R><A><L><K><T><R><L><Q><M><V><C><V><F><V><M><N><R><M><N><S><Q><N><S><G><F><T><Q><R><R><R><M><A><L><G><I><V><I><L><L><L><V><D><V><I><W><V><A><S><S><E><L><T><S><Y><V><F><T><Q><Y><N><K><P><F><F><S><T><F><A><K... | Putative solute transporter.<BOP> | Q8WV83 |
Q9Y5Y2 | NUBP2_HUMAN | Nucleotide-binding protein 2 | Homo | <M><E><A><A><A><E><P><G><N><L><A><G><V><R><H><I><I><L><V><L><S><G><K><G><G><V><G><K><S><T><I><S><T><E><L><A><L><A><L><R><H><A><G><K><K><V><G><I><L><D><V><D><L><C><G><P><S><I><P><R><M><L><G><A><Q><G><R><A><V><H><Q><C><D><R><G><W><A><P><V><F><L><D><R><E><Q><S><I><S><L><M><S><V><G><F><L><L><E><K><P><D><E><A><V><V><W><R><G... | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium... | Q9Y5Y2 |
A0A0B4J1V0 | HV315_HUMAN | Immunoglobulin heavy variable 3-15 | Homo | <M><E><F><G><L><S><W><I><F><L><A><A><I><L><K><G><V><Q><C><E><V><Q><L><V><E><S><G><G><G><L><V><K><P><G><G><S><L><R><L><S><C><A><A><S><G><F><T><F><S><N><A><W><M><S><W><V><R><Q><A><P><G><K><G><L><E><W><V><G><R><I><K><S><K><T><D><G><G><T><T><D><Y><A><A><P><V><K><G><R><F><T><I><S><R><D><D><S><K><N><T><L><Y><L><Q><M><N><S><L... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0B4J1V0 |
Q9H967 | WDR76_HUMAN | WD repeat-containing protein 76 | Homo | <M><S><R><S><G><A><A><A><E><K><A><D><S><R><Q><R><P><Q><M><K><V><N><E><Y><K><E><N><Q><N><I><A><Y><V><S><L><R><P><A><Q><T><T><V><L><I><K><T><A><K><V><Y><L><A><P><F><S><L><S><N><Y><Q><L><D><Q><L><M><C><P><K><S><L><S><E><K><N><S><N><N><E><V><A><C><K><K><T><K><I><K><K><T><C><R><R><I><I><P><P><K><M><K><N><T><S><S><K><A><E><S... | Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.<BOP> | Q9H967 |
P00966 | ASSY_HUMAN | Citrulline--aspartate ligase | Homo | <M><S><S><K><G><S><V><V><L><A><Y><S><G><G><L><D><T><S><C><I><L><V><W><L><K><E><Q><G><Y><D><V><I><A><Y><L><A><N><I><G><Q><K><E><D><F><E><E><A><R><K><K><A><L><K><L><G><A><K><K><V><F><I><E><D><V><S><R><E><F><V><E><E><F><I><W><P><A><I><Q><S><S><A><L><Y><E><D><R><Y><L><L><G><T><S><L><A><R><P><C><I><A><R><K><Q><V><E><I><A><Q... | One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of ar... | P00966 |
Q07955 | SRSF1_HUMAN | pre-mRNA-splicing factor SF2, P33 subunit | Homo | <M><S><G><G><G><V><I><R><G><P><A><G><N><N><D><C><R><I><Y><V><G><N><L><P><P><D><I><R><T><K><D><I><E><D><V><F><Y><K><Y><G><A><I><R><D><I><D><L><K><N><R><R><G><G><P><P><F><A><F><V><E><F><E><D><P><R><D><A><E><D><A><V><Y><G><R><D><G><Y><D><Y><D><G><Y><R><L><R><V><E><F><P><R><S><G><R><G><T><G><R><G><G><G><G><G><G><G><G><G><A... | Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice s... | Q07955 |
Q4G0S4 | C27C1_HUMAN | All-trans retinol 3,4-desaturase | Homo | <M><Q><T><S><A><M><A><L><L><A><R><I><L><R><A><G><L><R><P><A><P><E><R><G><G><L><L><G><G><G><A><P><R><R><P><Q><P><A><G><A><R><L><P><A><G><A><R><A><E><D><K><G><A><G><R><P><G><S><P><P><G><G><G><R><A><E><G><P><R><S><L><A><A><M><P><G><P><R><T><L><A><N><L><A><E><F><F><C><R><D><G><F><S><R><I><H><E><I><Q><Q><K><H><T><R><E><Y><G... | A cytochrome P450 monooxygenase that catalyzes the 3,4 desaturation of all-trans-retinol (also called vitamin A1) to all-trans-3,4-didehydroretinol (also called vitamin A2) in the skin. Desaturates with lower efficiency all-trans retinal and all-trans retinoic acid. Forms minor amounts of 3-hydroxy and 4-hydroxy all-tr... | Q4G0S4 |
Q9H3Y8 | PPDPF_HUMAN | Exocrine differentiation and proliferation factor | Homo | <M><A><A><I><P><S><S><G><S><L><V><A><T><H><D><Y><Y><R><R><R><L><G><S><T><S><S><N><S><S><C><S><S><T><E><C><P><G><E><A><I><P><H><P><P><G><L><P><K><A><D><P><G><H><W><W><A><S><F><F><F><G><K><S><T><L><P><F><M><A><T><V><L><E><S><A><E><H><S><E><P><P><Q><A><S><S><S><M><T><A><C><G><L><A><R><D><A><P><R><K><Q><P><G><G><Q><S><S><T... | Probable regulator of exocrine pancreas development.<BOP> | Q9H3Y8 |
Q8IVB4 | SL9A9_HUMAN | Solute carrier family 9 member 9 | Homo | <M><E><R><Q><S><R><V><M><S><E><K><D><E><Y><Q><F><Q><H><Q><G><A><V><E><L><L><V><F><N><F><L><L><I><L><T><I><L><T><I><W><L><F><K><N><H><R><F><R><F><L><H><E><T><G><G><A><M><V><Y><G><L><I><M><G><L><I><L><R><Y><A><T><A><P><T><D><I><E><S><G><T><V><Y><D><C><V><K><L><T><F><S><P><S><T><L><L><V><N><I><T><D><Q><V><Y><E><Y><K><Y><K... | May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell.<BOP> | Q8IVB4 |
P13995 | MTDC_HUMAN | Methenyltetrahydrofolate cyclohydrolase | Homo | <M><A><A><T><S><L><M><S><A><L><A><A><R><L><L><Q><P><A><H><S><C><S><L><R><L><R><P><F><H><L><A><A><V><R><N><E><A><V><V><I><S><G><R><K><L><A><Q><Q><I><K><Q><E><V><R><Q><E><V><E><E><W><V><A><S><G><N><K><R><P><H><L><S><V><I><L><V><G><E><N><P><A><S><H><S><Y><V><L><N><K><T><R><A><A><A><V><V><G><I><N><S><E><T><I><M><K><P><A><S... | Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.<BOP> | P13995 |
P31947 | 1433S_HUMAN | Stratifin | Homo | <M><E><R><A><S><L><I><Q><K><A><K><L><A><E><Q><A><E><R><Y><E><D><M><A><A><F><M><K><G><A><V><E><K><G><E><E><L><S><C><E><E><R><N><L><L><S><V><A><Y><K><N><V><V><G><G><Q><R><A><A><W><R><V><L><S><S><I><E><Q><K><S><N><E><E><G><S><E><E><K><G><P><E><V><R><E><Y><R><E><K><V><E><T><E><L><Q><G><V><C><D><T><V><L><G><L><L><D><S><H><L... | p53-regulated inhibitor of G2/M progression.<BOP> | P31947 |
Q8NBB4 | ZSCA1_HUMAN | Zinc finger and SCAN domain-containing protein 1 | Homo | <M><L><P><R><P><K><A><P><A><S><P><R><R><P><Q><T><P><T><P><S><E><Q><D><A><D><P><G><P><A><S><P><R><D><T><E><A><Q><R><L><R><F><R><Q><F><Q><Y><H><V><A><S><G><P><H><L><A><L><G><Q><L><W><T><L><C><R><Q><W><L><R><P><E><A><R><S><K><E><Q><M><L><E><L><L><V><L><E><Q><F><L><G><A><L><P><S><K><M><R><T><W><V><Q><S><Q><G><P><R><S><C><R... | May be involved in transcriptional regulation.<BOP> | Q8NBB4 |
P36021 | MOT8_HUMAN | X-linked PEST-containing transporter | Homo | <M><A><L><Q><S><Q><A><S><E><E><A><K><G><P><W><Q><E><A><D><Q><E><Q><Q><E><P><V><G><S><P><E><P><E><S><E><P><E><P><E><P><E><P><E><P><V><P><V><P><P><P><E><P><Q><P><E><P><Q><P><L><P><D><P><A><P><L><P><E><L><E><F><E><S><E><R><V><H><E><P><E><P><T><P><T><V><E><T><R><G><T><A><R><G><F><Q><P><P><E><G><G><F><G><W><V><V><V><F><A><A... | Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient. Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2) . Acts as an important mediator of... | P36021 |
Q9H596 | DUS21_HUMAN | Low molecular weight dual specificity phosphatase 21 | Homo | <M><T><A><S><A><S><S><F><S><S><S><Q><G><V><Q><Q><P><S><I><Y><S><F><S><Q><I><T><R><S><L><F><L><S><N><G><V><A><A><N><D><K><L><L><L><S><S><N><R><I><T><A><I><V><N><A><S><V><E><V><V><N><V><F><F><E><G><I><Q><Y><I><K><V><P><V><T><D><A><R><D><S><R><L><Y><D><F><F><D><P><I><A><D><L><I><H><T><I><D><M><R><Q><G><R><T><L><L><H><C><M... | Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.<BOP> | Q9H596 |
Q7Z5H5 | VN1R4_HUMAN | V1r-like receptor 4 | Homo | <M><A><S><R><Y><V><A><V><G><M><I><L><S><Q><T><V><V><G><V><L><G><S><F><S><V><L><L><H><Y><L><S><F><Y><C><T><G><C><R><L><R><S><T><D><L><I><V><K><H><L><I><V><A><N><F><L><A><L><R><C><K><G><V><P><Q><T><M><A><A><F><G><V><R><Y><F><L><N><A><L><G><C><K><L><V><F><Y><L><H><R><V><G><R><G><V><S><I><G><T><T><C><L><L><S><V><F><Q><V><I... | Putative pheromone receptor.<BOP> | Q7Z5H5 |
Q5VXT5 | SYPL2_HUMAN | Synaptophysin-like protein 2 | Homo | <M><S><S><T><E><S><A><G><R><T><A><D><K><S><P><R><Q><Q><V><D><R><L><L><V><G><L><R><W><R><R><L><E><E><P><L><G><F><I><K><V><L><Q><W><L><F><A><I><F><A><F><G><S><C><G><S><Y><S><G><E><T><G><A><M><V><R><C><N><N><E><A><K><D><V><S><S><I><I><V><A><F><G><Y><P><F><R><L><H><R><I><Q><Y><E><M><P><L><C><D><E><E><S><S><S><K><T><M><H><L... | Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes.<BOP> | Q5VXT5 |
Q8N6L0 | KASH5_HUMAN | KASH domain-containing protein 5 | Homo | <M><D><L><P><E><G><P><V><G><G><P><T><A><E><M><Y><L><R><E><R><P><E><E><A><R><L><G><M><P><V><S><L><E><E><Q><I><L><N><S><T><F><E><A><C><D><P><Q><R><T><G><T><V><A><V><A><Q><V><L><A><Y><L><E><A><V><T><G><Q><G><P><Q><D><A><R><L><Q><T><L><A><N><S><L><D><P><N><G><E><G><P><K><A><T><V><D><L><D><T><F><L><V><V><M><R><D><W><I><A><A... | As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and i... | Q8N6L0 |
Q6XE38 | SG1D4_HUMAN | IFN-gamma-inducible secretoglobin | Homo | <M><R><L><S><V><C><L><L><M><V><S><L><A><L><C><C><Y><Q><A><H><A><L><V><C><P><A><V><A><S><E><I><T><V><F><L><F><L><S><D><A><A><V><N><L><Q><V><A><K><L><N><P><P><P><E><A><L><A><A><K><L><E><V><K><H><C><T><D><Q><I><S><F><K><K><R><L><S><L><K><K><S><W><W><K> | Seems to be involved in the regulation of chemotactic cell migration and invasion.<BOP> | Q6XE38 |
P18621 | RL17_HUMAN | PD-1 | Homo | <M><V><R><Y><S><L><D><P><E><N><P><T><K><S><C><K><S><R><G><S><N><L><R><V><H><F><K><N><T><R><E><T><A><Q><A><I><K><G><M><H><I><R><K><A><T><K><Y><L><K><D><V><T><L><Q><K><Q><C><V><P><F><R><R><Y><N><G><G><V><G><R><C><A><Q><A><K><Q><W><G><W><T><Q><G><R><W><P><K><K><S><A><E><F><L><L><H><M><L><K><N><A><E><S><N><A><E><L><K><G><L... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP> | P18621 |
P00568 | KAD1_HUMAN | Myokinase | Homo | <M><E><E><K><L><K><K><T><K><I><I><F><V><V><G><G><P><G><S><G><K><G><T><Q><C><E><K><I><V><Q><K><Y><G><Y><T><H><L><S><T><G><D><L><L><R><S><E><V><S><S><G><S><A><R><G><K><K><L><S><E><I><M><E><K><G><Q><L><V><P><L><E><T><V><L><D><M><L><R><D><A><M><V><A><K><V><N><T><S><K><G><F><L><I><D><G><Y><P><R><E><V><Q><Q><G><E><E><F><E><R... | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP> | P00568 |
Q9ULV8 | CBLC_HUMAN | Signal transduction protein CBL-C | Homo | <M><A><L><A><V><A><P><W><G><R><Q><W><E><E><A><R><A><L><G><R><A><V><R><M><L><Q><R><L><E><E><Q><C><V><D><P><R><L><S><V><S><P><P><S><L><R><D><L><L><P><R><T><A><Q><L><L><R><E><V><A><H><S><R><R><A><A><G><G><G><G><P><G><G><P><G><G><S><G><D><F><L><L><I><Y><L><A><N><L><E><A><K><S><R><Q><V><A><A><L><L><P><P><R><G><R><R><S><A><N... | Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Functionally coupled with the E2 ubiquitin-protein ligases UB2D1, UB2D2 and UB2D3. Regulator of EGFR mediated signal transduc... | Q9ULV8 |
Q6IMI6 | ST1C3_HUMAN | Sulfotransferase 1C3 | Homo | <M><A><K><I><E><K><N><A><P><T><M><E><K><K><P><E><L><F><N><I><M><E><V><D><G><V><P><T><L><I><L><S><K><E><W><W><E><K><V><C><N><F><Q><A><K><P><D><D><L><I><L><A><T><Y><P><K><S><G><T><T><W><M><H><E><I><L><D><M><I><L><N><D><G><D><V><E><K><C><K><R><A><Q><T><L><D><R><H><A><F><L><E><L><K><F><P><H><K><E><K><P><D><L><E><F><V><L><E... | Exhibits weak sulphating activity and only toward chloro phenols (pentachlorophenol and 3,3',5,5'-tetrachloro-4,4'-biphenyldiol).<BOP> | Q6IMI6 |
Q8WVI7 | PPR1C_HUMAN | Inhibitor-5 of protein phosphatase 1 | Homo | <M><E><P><N><S><P><K><K><I><Q><F><A><V><P><V><F><Q><S><Q><I><A><P><E><A><A><E><Q><I><R><K><R><R><P><T><P><A><S><L><V><I><L><N><E><H><N><P><P><E><I><D><D><K><R><G><P><N><T><Q><G><E><L><Q><N><A><S><P><K><Q><R><K><Q><S><V><Y><T><P><P><T><I><K><G><V><K><H><L><K><G><Q><N><E><S><A><F><P><E><E><E><E><G><T><N><E><R><E><E><Q><R... | May increase cell susceptibility to TNF-induced apoptosis.<BOP> | Q8WVI7 |
Q96A47 | ISL2_HUMAN | Insulin gene enhancer protein ISL-2 | Homo | <M><V><D><I><I><F><H><Y><P><F><L><G><A><M><G><D><H><S><K><K><K><P><G><T><A><M><C><V><G><C><G><S><Q><I><H><D><Q><F><I><L><R><V><S><P><D><L><E><W><H><A><A><C><L><K><C><A><E><C><S><Q><Y><L><D><E><T><C><T><C><F><V><R><D><G><K><T><Y><C><K><R><D><Y><V><R><L><F><G><I><K><C><A><K><C><Q><V><G><F><S><S><S><D><L><V><M><R><A><R><D... | Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.<BOP> | Q96A47 |
O60481 | ZIC3_HUMAN | Zinc finger protein of the cerebellum 3 | Homo | <M><T><M><L><L><D><G><G><P><Q><F><P><G><L><G><V><G><S><F><G><A><P><R><H><H><E><M><P><N><R><E><P><A><G><M><G><L><N><P><F><G><D><S><T><H><A><A><A><A><A><A><A><A><A><A><F><K><L><S><P><A><A><A><H><D><L><S><S><G><Q><S><S><A><F><T><P><Q><G><S><G><Y><A><N><A><L><G><H><H><H><H><H><H><H><H><H><H><H><T><S><Q><V><P><S><Y><G><G><A... | Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.<BOP> | O60481 |
O00425 | IF2B3_HUMAN | VICKZ family member 3 | Homo | <M><N><K><L><Y><I><G><N><L><S><E><N><A><A><P><S><D><L><E><S><I><F><K><D><A><K><I><P><V><S><G><P><F><L><V><K><T><G><Y><A><F><V><D><C><P><D><E><S><W><A><L><K><A><I><E><A><L><S><G><K><I><E><L><H><G><K><P><I><E><V><E><H><S><V><P><K><R><Q><R><I><R><K><L><Q><I><R><N><I><P><P><H><L><Q><W><E><V><L><D><S><L><L><V><Q><Y><G><V><V... | RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclea... | O00425 |
Q9BYV6 | TRI55_HUMAN | RING finger protein 29 | Homo | <M><S><A><S><L><N><Y><K><S><F><S><K><E><Q><Q><T><M><D><N><L><E><K><Q><L><I><C><P><I><C><L><E><M><F><T><K><P><V><V><I><L><P><C><Q><H><N><L><C><R><K><C><A><S><D><I><F><Q><A><S><N><P><Y><L><P><T><R><G><G><T><T><M><A><S><G><G><R><F><R><C><P><S><C><R><H><E><V><V><L><D><R><H><G><V><Y><G><L><Q><R><N><L><L><V><E><N><I><I><D><I... | May regulate gene expression and protein turnover in muscle cells.<BOP> | Q9BYV6 |
P17516 | AK1C4_HUMAN | HAKRA | Homo | <M><D><P><K><Y><Q><R><V><E><L><N><D><G><H><F><M><P><V><L><G><F><G><T><Y><A><P><P><E><V><P><R><N><R><A><V><E><V><T><K><L><A><I><E><A><G><F><R><H><I><D><S><A><Y><L><Y><N><N><E><E><Q><V><G><L><A><I><R><S><K><I><A><D><G><S><V><K><R><E><D><I><F><Y><T><S><K><L><W><C><T><F><F><Q><P><Q><M><V><Q><P><A><L><E><S><S><L><K><K><L><Q... | Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Liver specific enzyme that acts as NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid nucleus and side chain . Displays the ability to catalyze both oxidation and reduction in vit... | P17516 |
Q15027 | ACAP1_HUMAN | Centaurin-beta-1 | Homo | <M><T><V><K><L><D><F><E><E><C><L><K><D><S><P><R><F><R><A><S><I><E><L><V><E><A><E><V><S><E><L><E><T><R><L><E><K><L><L><K><L><G><T><G><L><L><E><S><G><R><H><Y><L><A><A><S><R><A><F><V><V><G><I><C><D><L><A><R><L><G><P><P><E><P><M><M><A><E><C><L><E><K><F><T><V><S><L><N><H><K><L><D><S><H><A><E><L><L><D><A><T><Q><H><T><L><Q><Q... | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<BOP> | Q15027 |
Q9UHX1 | PUF60_HUMAN | Siah-binding protein 1 | Homo | <M><A><T><A><T><I><A><L><Q><V><N><G><Q><Q><G><G><G><S><E><P><A><A><A><A><A><V><V><A><A><G><D><K><W><K><P><P><Q><G><T><D><S><I><K><M><E><N><G><Q><S><T><A><A><K><L><G><L><P><P><L><T><P><E><Q><Q><E><A><L><Q><K><A><K><K><Y><A><M><E><Q><S><I><K><S><V><L><V><K><Q><T><I><A><H><Q><Q><Q><Q><L><T><N><L><Q><M><A><A><V><T><M><G><F... | DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH ba... | Q9UHX1 |
P28070 | PSB4_HUMAN | Proteasome chain 3 | Homo | <M><E><A><F><L><G><S><R><S><G><L><W><A><G><G><P><A><P><G><Q><F><Y><R><I><P><S><T><P><D><S><F><M><D><P><A><S><A><L><Y><R><G><P><I><T><R><T><Q><N><P><M><V><T><G><T><S><V><L><G><V><K><F><E><G><G><V><V><I><A><A><D><M><L><G><S><Y><G><S><L><A><R><F><R><N><I><S><R><I><M><R><V><N><N><S><T><M><L><G><A><S><G><D><Y><A><D><F><Q><Y... | Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and th... | P28070 |
P33241 | LSP1_HUMAN | Lymphocyte-specific antigen WP34 | Homo | <M><A><E><A><S><S><D><P><G><A><E><E><R><E><E><L><L><G><P><T><A><Q><W><S><V><E><D><E><E><E><A><V><H><E><Q><C><Q><H><E><R><D><R><Q><L><Q><A><Q><D><E><E><G><G><G><H><V><P><E><R><P><K><Q><E><M><L><L><S><L><K><P><S><E><A><P><E><L><D><E><D><E><G><F><G><D><W><S><Q><R><P><E><Q><R><Q><Q><H><E><G><A><Q><G><A><L><D><S><G><E><P><P... | May play a role in mediating neutrophil activation and chemotaxis.<BOP> | P33241 |
Q96BP3 | PPWD1_HUMAN | Spliceosome-associated cyclophilin | Homo | <M><A><A><E><S><G><S><D><F><Q><Q><R><R><R><R><R><R><D><P><E><E><P><E><K><T><E><L><S><E><R><E><L><A><V><A><V><A><V><S><Q><E><N><D><E><E><N><E><E><R><W><V><G><P><L><P><V><E><A><T><L><A><K><K><R><K><V><L><E><F><E><R><V><Y><L><D><N><L><P><S><A><S><M><Y><E><R><S><Y><M><H><R><D><V><I><T><H><V><V><C><T><K><T><D><F><I><I><T><A... | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding . May be involved in pre-mRNA splicing .<BOP> | Q96BP3 |
Q96FV3 | TSN17_HUMAN | Transmembrane 4 superfamily member 17 | Homo | <M><P><G><K><H><Q><H><F><Q><E><P><E><V><G><C><C><G><K><Y><F><L><F><G><F><N><I><V><F><W><V><L><G><A><L><F><L><A><I><G><L><W><A><W><G><E><K><G><V><L><S><N><I><S><A><L><T><D><L><G><G><L><D><P><V><W><L><F><V><V><V><G><G><V><M><S><V><L><G><F><A><G><C><I><G><A><L><R><E><N><T><F><L><L><K><F><F><S><V><F><L><G><L><I><F><F><L><E... | Regulates ADAM10 maturation.<BOP> | Q96FV3 |
Q7Z3I7 | ZN572_HUMAN | Zinc finger protein 572 | Homo | <M><E><Q><E><K><K><L><L><V><S><D><S><N><S><F><M><E><R><E><S><L><K><S><P><F><T><G><D><T><S><M><N><N><L><E><T><V><H><H><N><N><S><K><A><D><K><L><K><E><K><P><S><E><W><S><K><R><H><R><P><Q><H><Y><K><H><E><D><A><K><E><M><P><L><T><W><V><Q><D><E><I><W><C><H><D><S><Y><E><S><D><G><K><S><E><N><W><G><N><F><I><A><K><E><E><E><K><P><N... | May be involved in transcriptional regulation.<BOP> | Q7Z3I7 |
Q9BW60 | ELOV1_HUMAN | Very long chain 3-oxoacyl-CoA synthase 1 | Homo | <M><E><A><V><V><N><L><Y><Q><E><V><M><K><H><A><D><P><R><I><Q><G><Y><P><L><M><G><S><P><L><L><M><T><S><I><L><L><T><Y><V><Y><F><V><L><S><L><G><P><R><I><M><A><N><R><K><P><F><Q><L><R><G><F><M><I><V><Y><N><F><S><L><V><A><L><S><L><Y><I><V><Y><E><F><L><M><S><G><W><L><S><T><Y><T><W><R><C><D><P><V><D><Y><S><N><S><P><E><A><L><R><M... | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle . This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits... | Q9BW60 |
Q8N8A6 | DDX51_HUMAN | DEAD box protein 51 | Homo | <M><A><L><F><Y><V><A><R><Y><P><G><P><D><A><A><A><A><A><G><P><E><G><A><E><A><G><A><H><G><R><A><R><A><L><L><E><R><L><Q><S><R><A><R><E><R><Q><Q><Q><R><E><P><A><Q><T><E><A><A><A><S><T><E><P><A><T><R><R><R><R><R><P><R><R><R><R><R><V><N><D><A><E><P><G><S><P><E><A><P><Q><G><K><R><R><K><A><D><G><E><D><A><G><A><E><S><N><E><E><A... | ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.<BOP> | Q8N8A6 |
P42685 | FRK_HUMAN | Protein-tyrosine kinase 5 | Homo | <M><S><N><I><C><Q><R><L><W><E><Y><L><E><P><Y><L><P><C><L><S><T><E><A><D><K><S><T><V><I><E><N><P><G><A><L><C><S><P><Q><S><Q><R><H><G><H><Y><F><V><A><L><F><D><Y><Q><A><R><T><A><E><D><L><S><F><R><A><G><D><K><L><Q><V><L><D><T><L><H><E><G><W><W><F><A><R><H><L><E><K><R><R><D><G><S><S><Q><Q><L><Q><G><Y><I><P><S><N><Y><V><A><E... | Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.<BOP> | P42685 |
O95484 | CLD9_HUMAN | Claudin-9 | Homo | <M><A><S><T><G><L><E><L><L><G><M><T><L><A><V><L><G><W><L><G><T><L><V><S><C><A><L><P><L><W><K><V><T><A><F><I><G><N><S><I><V><V><A><Q><V><V><W><E><G><L><W><M><S><C><V><V><Q><S><T><G><Q><M><Q><C><K><V><Y><D><S><L><L><A><L><P><Q><D><L><Q><A><A><R><A><L><C><V><I><A><L><L><L><A><L><L><G><L><L><V><A><I><T><G><A><Q><C><T><T><C... | (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.<BOP> | O95484 |
Q567V2 | M17L2_HUMAN | Mpv17-like protein 2 | Homo | <M><A><R><G><G><W><R><R><L><R><R><L><L><S><A><G><Q><L><L><F><Q><G><R><A><L><L><V><T><N><T><L><G><C><G><A><L><M><A><A><G><D><G><V><R><Q><S><W><E><I><R><A><R><P><G><Q><V><F><D><P><R><R><S><A><S><M><F><A><V><G><C><S><M><G><P><F><L><H><Y><W><Y><L><S><L><D><R><L><F><P><A><S><G><L><R><G><F><P><N><V><L><K><K><V><L><V><D><Q><L... | Required for the assembly and stability of the mitochondrial ribosome . Is a positive regulator of mitochondrial protein synthesis .<BOP> | Q567V2 |
Q6ZUX7 | LHPL2_HUMAN | Lipoma HMGIC fusion partner-like 2 protein | Homo | <M><C><H><V><I><V><T><C><R><S><M><L><W><T><L><L><S><I><V><V><A><F><A><E><L><I><A><F><M><S><A><D><W><L><I><G><K><A><R><S><R><G><G><V><E><P><A><G><P><G><G><G><S><P><E><P><Y><H><P><T><L><G><I><Y><A><R><C><I><R><N><P><G><V><Q><H><F><Q><R><D><T><L><C><G><P><Y><A><E><S><F><G><E><I><A><S><G><F><W><Q><A><T><A><I><F><L><A><V><G... | Plays a role in female and male fertility. Involved in distal reproductive tract development.<BOP> | Q6ZUX7 |
P08567 | PLEK_HUMAN | Platelet 47 kDa protein | Homo | <M><E><P><K><R><I><R><E><G><Y><L><V><K><K><G><S><V><F><N><T><W><K><P><M><W><V><V><L><L><E><D><G><I><E><F><Y><K><K><K><S><D><N><S><P><K><G><M><I><P><L><K><G><S><T><L><T><S><P><C><Q><D><F><G><K><R><M><F><V><F><K><I><T><T><T><K><Q><Q><D><H><F><F><Q><A><A><F><L><E><E><R><D><A><W><V><R><D><I><K><K><A><I><K><C><I><E><G><G><Q... | Major protein kinase C substrate of platelets.<BOP> | P08567 |
P27701 | CD82_HUMAN | Tetraspanin-27 | Homo | <M><G><S><A><C><I><K><V><T><K><Y><F><L><F><L><F><N><L><I><F><F><I><L><G><A><V><I><L><G><F><G><V><W><I><L><A><D><K><S><S><F><I><S><V><L><Q><T><S><S><S><S><L><R><M><G><A><Y><V><F><I><G><V><G><A><V><T><M><L><M><G><F><L><G><C><I><G><A><V><N><E><V><R><C><L><L><G><L><Y><F><A><F><L><L><L><I><L><I><A><Q><V><T><A><G><A><L><F><Y... | Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.<BOP> | P27701 |
Q9ULZ0 | T53G3_HUMAN | TP53-inducible gene 3 protein | Homo | <M><R><A><S><P><C><I><S><Q><P><A><A><S><W><H><P><R><P><S><A><L><R><P><T><A><G><S><G><P><D><T><R><T><P><G><T><V><E><D><G><S><A><P><C><P><A><F><R><S><P><A><V><S><P><C><G><E><E><P><C><C><F><Q><I><S><P><A><E><E><T><L><E><L><G><R><L><V><S><P><G><N><C><D><T><L><S><P><R><A><A><G><F><Y><A><C><H><V><R><S><L><I><P><C><R><S><T><K... | May play a significant role in p53/TP53-mediating signaling pathway.<BOP> | Q9ULZ0 |
P32970 | CD70_HUMAN | Tumor necrosis factor ligand superfamily member 7 | Homo | <M><P><E><E><G><S><G><C><S><V><R><R><R><P><Y><G><C><V><L><R><A><A><L><V><P><L><V><A><G><L><V><I><C><L><V><V><C><I><Q><R><F><A><Q><A><Q><Q><Q><L><P><L><E><S><L><G><W><D><V><A><E><L><Q><L><N><H><T><G><P><Q><Q><D><P><R><L><Y><W><Q><G><G><P><A><L><G><R><S><F><L><H><G><P><E><L><D><K><G><Q><L><R><I><H><R><D><G><I><Y><M><V><H... | Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.<BOP> | P32970 |
Q8WXI9 | P66B_HUMAN | p66/p68 | Homo | <M><D><R><M><T><E><D><A><L><R><L><N><L><L><K><R><S><L><D><P><A><D><E><R><D><D><V><L><A><K><R><L><K><M><E><G><H><E><A><M><E><R><L><K><M><L><A><L><L><K><R><K><D><L><A><N><L><E><V><P><H><E><L><P><T><K><Q><D><G><S><G><V><K><G><Y><E><E><K><L><N><G><N><L><R><P><H><G><D><N><R><T><A><G><R><P><G><K><E><N><I><N><D><E><P><V><D><M... | Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.<BOP> | Q8WXI9 |
P13489 | RINI_HUMAN | Ribonuclease/angiogenin inhibitor 1 | Homo | <M><S><L><D><I><Q><S><L><D><I><Q><C><E><E><L><S><D><A><R><W><A><E><L><L><P><L><L><Q><Q><C><Q><V><V><R><L><D><D><C><G><L><T><E><A><R><C><K><D><I><S><S><A><L><R><V><N><P><A><L><A><E><L><N><L><R><S><N><E><L><G><D><V><G><V><H><C><V><L><Q><G><L><Q><T><P><S><C><K><I><Q><K><L><S><L><Q><N><C><C><L><T><G><A><G><C><G><V><L><S><S... | Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.<BOP> | P13489 |
Q9H0A6 | RNF32_HUMAN | RING finger protein 32 | Homo | <M><L><K><N><K><G><H><S><S><K><K><D><N><L><A><V><N><A><V><A><L><Q><D><H><I><L><H><D><L><Q><L><R><N><L><S><V><A><D><H><S><K><T><Q><V><Q><K><K><E><N><K><S><L><K><R><D><T><K><A><I><I><D><T><G><L><K><K><T><T><Q><C><P><K><L><E><D><S><E><K><E><Y><V><L><D><P><K><P><P><P><L><T><L><A><Q><K><L><G><L><I><G><P><P><P><P><P><L><S><S... | May play a role in sperm formation.<BOP> | Q9H0A6 |
Q969H6 | POP5_HUMAN | Ribonuclease P/MRP protein subunit POP5 | Homo | <M><V><R><F><K><H><R><Y><L><L><C><E><L><V><S><D><D><P><R><C><R><L><S><L><D><D><R><V><L><S><S><L><V><R><D><T><I><A><R><V><H><G><T><F><G><A><A><A><C><S><I><G><F><A><V><R><Y><L><N><A><Y><T><G><I><V><L><L><R><C><R><K><E><F><Y><Q><L><V><W><S><A><L><P><F><I><T><Y><L><E><N><K><G><H><R><Y><P><C><F><F><N><T><L><H><V><G><G><T><I... | Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends . Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences .<BOP> | Q969H6 |
P78417 | GSTO1_HUMAN | S-(Phenacyl)glutathione reductase | Homo | <M><S><G><E><S><A><R><S><L><G><K><G><S><A><P><P><G><P><V><P><E><G><S><I><R><I><Y><S><M><R><F><C><P><F><A><E><R><T><R><L><V><L><K><A><K><G><I><R><H><E><V><I><N><I><N><L><K><N><K><P><E><W><F><F><K><K><N><P><F><G><L><V><P><V><L><E><N><S><Q><G><Q><L><I><Y><E><S><A><I><T><C><E><Y><L><D><E><A><Y><P><G><K><K><L><L><P><D><D><P... | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.<BOP> | P78417 |
Q96MD2 | KICS2_HUMAN | KICSTOR complex protein C12orf66 | Homo | <M><G><E><S><I><P><L><A><A><P><V><P><V><E><Q><A><V><L><E><T><F><F><S><H><L><G><I><F><S><Y><D><K><A><K><D><N><V><E><K><E><R><E><A><N><K><S><A><G><G><S><W><L><S><L><L><A><A><L><A><H><L><A><A><A><E><K><V><Y><H><S><L><T><Y><L><G><Q><K><L><G><G><Q><S><F><F><S><R><K><D><S><I><R><T><I><Y><T><S><L><H><N><E><L><K><K><V><V><T><G... | As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to nega... | Q96MD2 |
Q9H4X1 | RGCC_HUMAN | Response gene to complement 32 protein | Homo | <M><K><P><P><A><A><Q><G><S><P><A><A><A><A><A><A><A><P><A><L><D><S><A><A><A><E><D><L><S><D><A><L><C><E><F><D><A><V><L><A><D><F><A><S><P><F><H><E><R><H><F><H><Y><E><E><H><L><E><R><M><K><R><R><S><S><A><S><V><S><D><S><S><G><F><S><D><S><E><S><A><D><S><L><Y><R><N><S><F><S><F><S><D><E><K><L><N><S><P><T><D><S><T><P><A><L><L><S... | Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast... | Q9H4X1 |
Q7Z3D6 | GLUCM_HUMAN | D-glutamate cyclase, mitochondrial | Homo | <M><P><F><T><L><H><L><R><S><R><L><P><S><A><I><R><S><L><I><L><Q><K><K><P><N><I><R><N><T><S><S><M><A><G><E><L><R><P><A><S><L><V><V><L><P><R><S><L><A><P><A><F><E><R><F><C><Q><V><N><T><G><P><L><P><L><L><G><Q><S><E><P><E><K><W><M><L><P><P><Q><G><A><I><S><E><T><R><M><G><H><P><Q><F><W><K><Y><E><F><G><A><C><T><G><S><L><A><S><L... | D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline.<BOP> | Q7Z3D6 |
Q14376 | GALE_HUMAN | UDP-galactose 4-epimerase | Homo | <M><A><E><K><V><L><V><T><G><G><A><G><Y><I><G><S><H><T><V><L><E><L><L><E><A><G><Y><L><P><V><V><I><D><N><F><H><N><A><F><R><G><G><G><S><L><P><E><S><L><R><R><V><Q><E><L><T><G><R><S><V><E><F><E><E><M><D><I><L><D><Q><G><A><L><Q><R><L><F><K><K><Y><S><F><M><A><V><I><H><F><A><G><L><K><A><V><G><E><S><V><Q><K><P><L><D><Y><Y><R><V... | Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is conve... | Q14376 |
Q8NGQ3 | OR1S2_HUMAN | Olfactory receptor OR11-231 | Homo | <M><K><T><L><C><S><F><L><Q><I><S><R><N><M><H><Q><E><N><Q><T><T><I><T><E><F><I><L><L><G><L><S><N><Q><A><E><H><Q><N><L><L><F><V><L><F><L><S><M><Y><V><V><T><V><V><G><N><G><L><I><I><V><A><I><S><L><D><I><Y><L><H><T><P><M><Y><L><F><L><A><Y><L><S><F><A><D><I><S><S><I><S><N><S><V><P><K><M><L><V><N><I><Q><T><N><S><Q><S><I><S><Y... | Odorant receptor.<BOP> | Q8NGQ3 |
O95379 | TFIP8_HUMAN | TNF-induced protein GG2-1 | Homo | <M><H><S><E><A><E><E><S><K><E><V><A><T><D><V><F><N><S><K><N><L><A><V><Q><A><Q><K><K><I><L><G><K><M><V><S><K><S><I><A><T><T><L><I><D><D><T><S><S><E><V><L><D><E><L><Y><R><V><T><R><E><Y><T><Q><N><K><K><E><A><E><K><I><I><K><N><L><I><K><T><V><I><K><L><A><I><L><Y><R><N><N><Q><F><N><Q><D><E><L><A><L><M><E><K><F><K><K><K><V><H... | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.<BOP> | O95379 |
P46094 | XCR1_HUMAN | XC chemokine receptor 1 | Homo | <M><E><S><S><G><N><P><E><S><T><T><F><F><Y><Y><D><L><Q><S><Q><P><C><E><N><Q><A><W><V><F><A><T><L><A><T><T><V><L><Y><C><L><V><F><L><L><S><L><V><G><N><S><L><V><L><W><V><L><V><K><Y><E><S><L><E><S><L><T><N><I><F><I><L><N><L><C><L><S><D><L><V><F><A><C><L><L><P><V><W><I><S><P><Y><H><W><G><W><V><L><G><D><F><L><C><K><L><L><N><M... | Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin.<BOP> | P46094 |
Q8NBS9 | TXND5_HUMAN | Thioredoxin-like protein p46 | Homo | <M><P><A><R><P><G><R><L><L><P><L><L><A><R><P><A><A><L><T><A><L><L><L><L><L><L><G><H><G><G><G><G><R><W><G><A><R><A><Q><E><A><A><A><A><A><A><D><G><P><P><A><A><D><G><E><D><G><Q><D><P><H><S><K><H><L><Y><T><A><D><M><F><T><H><G><I><Q><S><A><A><H><F><V><M><F><F><A><P><W><C><G><H><C><Q><R><L><Q><P><T><W><N><D><L><G><D><K><Y><N... | Protein disulfide isomerase of the endoplasmic reticulum lumen involved in the formation of disulfide bonds in proteins. Can reduce insulin disulfide bonds.<BOP> | Q8NBS9 |
Q5TBB1 | RNH2B_HUMAN | Ribonuclease HI subunit B | Homo | <M><A><A><G><V><D><C><G><D><G><V><G><A><R><Q><H><V><F><L><V><S><E><Y><L><K><D><A><S><K><K><M><K><N><G><L><M><F><V><K><L><V><N><P><C><S><G><E><G><A><I><Y><L><F><N><M><C><L><Q><Q><L><F><E><V><K><V><F><K><E><K><H><H><S><W><F><I><N><Q><S><V><Q><S><G><G><L><L><H><F><A><T><P><V><D><P><L><F><L><L><L><H><Y><L><I><K><A><D><K><E... | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.<BOP> | Q5TBB1 |
Q8WWY7 | WFD12_HUMAN | Whey acidic protein 2 | Homo | <M><G><S><S><S><F><L><V><L><M><V><S><L><V><L><V><T><L><V><A><V><E><G><V><K><E><G><I><E><K><A><G><V><C><P><A><D><N><V><R><C><F><K><S><D><P><P><Q><C><H><T><D><Q><D><C><L><G><E><R><K><C><C><Y><L><H><C><G><F><K><C><V><I><P><V><K><E><L><E><E><G><G><N><K><D><E><D><V><S><R><P><Y><P><E><P><G><W><E><A><K><C><P><G><S><S><S><T><R... | Antibacterial protein. Putative acid-stable proteinase inhibitor.<BOP> | Q8WWY7 |
Q8IWE2 | NXP20_HUMAN | Protein FAM114A1 | Homo | <M><S><D><D><A><G><D><T><L><A><T><G><D><K><A><E><V><T><E><M><P><N><S><D><S><L><P><E><D><A><E><V><H><C><D><S><A><A><V><S><H><E><P><T><P><A><D><P><R><G><E><G><H><E><N><A><A><V><Q><G><A><G><A><A><A><I><G><P><P><V><Q><P><Q><D><A><N><A><L><E><P><P><L><N><G><D><V><T><E><D><T><L><A><E><C><I><D><S><V><S><L><E><A><E><P><R><S><E... | May play a role in neuronal cell development.<BOP> | Q8IWE2 |
Q6ICG8 | WBP2L_HUMAN | WW domain-binding protein 2-like | Homo | <M><A><V><N><Q><S><H><T><E><N><R><R><G><A><L><I><P><N><G><E><S><L><L><K><R><S><P><N><V><E><L><S><F><P><Q><R><S><E><G><S><N><V><F><S><G><R><K><T><G><T><L><F><L><T><S><Y><R><V><I><F><I><T><S><C><S><I><S><D><P><M><L><S><F><M><M><P><F><D><L><M><T><N><L><T><V><E><Q><P><V><F><A><A><N><F><I><K><G><T><I><Q><A><A><P><Y><G><G><W... | May play a role in meiotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.<BOP> | Q6ICG8 |
Q9BXD5 | NPL_HUMAN | Sialic acid lyase | Homo | <M><A><F><P><K><K><K><L><Q><G><L><V><A><A><T><I><T><P><M><T><E><N><G><E><I><N><F><S><V><I><G><Q><Y><V><D><Y><L><V><K><E><Q><G><V><K><N><I><F><V><N><G><T><T><G><E><G><L><S><L><S><V><S><E><R><R><Q><V><A><E><E><W><V><T><K><G><K><D><K><L><D><Q><V><I><I><H><V><G><A><L><S><L><K><E><S><Q><E><L><A><Q><H><A><A><E><I><G><A><D><G... | Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate . It prevents sialic acids from being recycled and returning to the cell surface . Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway . Although human is not able t... | Q9BXD5 |
P53004 | BIEA_HUMAN | Biliverdin-IX alpha-reductase | Homo | <M><N><A><E><P><E><R><K><F><G><V><V><V><V><G><V><G><R><A><G><S><V><R><M><R><D><L><R><N><P><H><P><S><S><A><F><L><N><L><I><G><F><V><S><R><R><E><L><G><S><I><D><G><V><Q><Q><I><S><L><E><D><A><L><S><S><Q><E><V><E><V><A><Y><I><C><S><E><S><S><S><H><E><D><Y><I><R><Q><F><L><N><A><G><K><H><V><L><V><E><Y><P><M><T><L><S><L><A><A><A... | Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor . Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7) . NADPH, however, is the p... | P53004 |
Q9NP56 | PDE7B_HUMAN | cAMP-specific 3',5'-cyclic phosphodiesterase 7B | Homo | <M><S><C><L><M><V><E><R><C><G><E><I><L><F><E><N><P><D><Q><N><A><K><C><V><C><M><L><G><D><I><R><L><R><G><Q><T><G><V><R><A><E><R><R><G><S><Y><P><F><I><D><F><R><L><L><N><S><T><T><Y><S><G><E><I><G><T><K><K><K><V><K><R><L><L><S><F><Q><R><Y><F><H><A><S><R><L><L><R><G><I><I><P><Q><A><P><L><H><L><L><D><E><D><Y><L><G><Q><A><R><H... | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes . May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain .<BOP> | Q9NP56 |
Q86Y27 | BAGE5_HUMAN | Cancer/testis antigen 2.5 | Homo | <M><A><A><G><A><V><F><L><A><L><S><A><Q><L><L><Q><A><R><L><M><K><E><E><S><P><V><V><S><W><R><L><E><P><E><D><G><T><A><L><C><F><I><F> | Unknown. Candidate gene encoding tumor antigens.<BOP> | Q86Y27 |
Q14140 | SRTD2_HUMAN | Transcriptional regulator interacting with the PHD-bromodomain 2 | Homo | <M><L><G><K><G><G><K><R><K><F><D><E><H><E><D><G><L><E><G><K><I><V><S><P><C><D><G><P><S><K><V><S><Y><T><L><Q><R><Q><T><I><F><N><I><S><L><M><K><L><Y><N><H><R><P><L><T><E><P><S><L><Q><K><T><V><L><I><N><N><M><L><R><R><I><Q><E><E><L><K><Q><E><G><S><L><R><P><M><F><T><P><S><S><Q><P><T><T><E><P><S><D><S><Y><R><E><A><P><P><A><F... | Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Mod... | Q14140 |
Q5JPH6 | SYEM_HUMAN | Glutamyl-tRNA synthetase | Homo | <M><A><A><L><L><R><R><L><L><Q><R><E><R><P><S><A><A><S><G><R><P><V><G><R><R><E><A><N><L><G><T><D><A><G><V><A><V><R><V><R><F><A><P><S><P><T><G><F><L><H><L><G><G><L><R><T><A><L><Y><N><Y><I><F><A><K><K><Y><Q><G><S><F><I><L><R><L><E><D><T><D><Q><T><R><V><V><P><G><A><A><E><N><I><E><D><M><L><E><W><A><G><I><P><P><D><E><S><P><R... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | Q5JPH6 |
Q0VGL1 | LTOR4_HUMAN | Ragulator complex protein LAMTOR4, N-terminally processed | Homo | <M><T><S><A><L><T><Q><G><L><E><R><I><P><D><Q><L><G><Y><L><V><L><S><E><G><A><V><L><A><S><S><G><D><L><E><N><D><E><Q><A><A><S><A><I><S><E><L><V><S><T><A><C><G><F><R><L><H><R><G><M><N><V><P><F><K><R><L><S><V><V><F><G><E><H><T><L><L><V><T><V><S><G><Q><R><V><F><V><V><K><R><Q><N><R><G><R><E><P><I><D><V> | As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nuc... | Q0VGL1 |
Q9BTV6 | DPH7_HUMAN | WD repeat-containing protein 85 | Homo | <M><M><G><C><F><A><L><Q><T><V><D><T><E><L><T><A><D><S><V><E><W><C><P><L><Q><G><C><R><H><L><L><A><C><G><T><Y><Q><L><R><R><P><E><D><R><P><A><G><P><Q><N><K><G><G><M><E><V><K><E><P><Q><V><R><L><G><R><L><F><L><Y><S><F><N><D><N><N><S><I><H><P><L><V><E><V><Q><R><K><D><T><S><A><I><L><D><M><K><W><C><H><I><P><V><A><G><H><A><L><L... | Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).<BOP> | Q9BTV6 |
Q5JTY5 | ZNG1C_HUMAN | Cobalamin synthase W domain-containing protein 3 | Homo | <M><L><P><A><V><G><S><V><D><E><E><E><D><P><A><E><E><D><C><P><E><L><V><P><I><E><T><T><Q><S><E><E><E><E><K><S><G><L><G><A><K><I><P><V><T><I><I><T><G><Y><L><G><A><G><K><T><T><L><L><N><Y><I><L><T><E><Q><H><S><K><R><V><A><V><I><L><N><E><S><G><E><G><S><A><L><E><K><S><L><A><V><S><Q><G><G><E><L><Y><E><E><W><L><E><L><R><N><G><C... | Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-term... | Q5JTY5 |
P18089 | ADA2B_HUMAN | Alpha-2B adrenoreceptor | Homo | <M><D><H><Q><D><P><Y><S><V><Q><A><T><A><A><I><A><A><A><I><T><F><L><I><L><F><T><I><F><G><N><A><L><V><I><L><A><V><L><T><S><R><S><L><R><A><P><Q><N><L><F><L><V><S><L><A><A><A><D><I><L><V><A><T><L><I><I><P><F><S><L><A><N><E><L><L><G><Y><W><Y><F><R><R><T><W><C><E><V><Y><L><A><L><D><V><L><F><C><T><S><S><I><V><H><L><C><A><I><S... | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octo... | P18089 |
Q8N695 | SC5A8_HUMAN | Solute carrier family 5 member 8 | Homo | <M><D><T><P><R><G><I><G><T><F><V><V><W><D><Y><V><V><F><A><G><M><L><V><I><S><A><A><I><G><I><Y><Y><A><F><A><G><G><G><Q><Q><T><S><K><D><F><L><M><G><G><R><R><M><T><A><V><P><V><A><L><S><L><T><A><S><F><M><S><A><V><T><V><L><G><T><P><S><E><V><Y><R><F><G><A><I><F><S><I><F><A><F><T><Y><F><F><V><V><V><I><S><A><E><V><F><L><P><V><F... | Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate an... | Q8N695 |
O43508 | TNF12_HUMAN | Tumor necrosis factor ligand superfamily member 12, secreted form | Homo | <M><A><A><R><R><S><Q><R><R><R><G><R><R><G><E><P><G><T><A><L><L><V><P><L><A><L><G><L><G><L><A><L><A><C><L><G><L><L><L><A><V><V><S><L><G><S><R><A><S><L><S><A><Q><E><P><A><Q><E><E><L><V><A><E><E><D><Q><D><P><S><E><L><N><P><Q><T><E><E><S><Q><D><P><A><P><F><L><N><R><L><V><R><P><R><R><S><A><P><K><G><R><K><T><R><A><R><R><A><I... | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.<BOP> | O43508 |
D6RCP7 | U17LJ_HUMAN | Ubiquitin carboxyl-terminal hydrolase 17-like protein 19 | Homo | <M><E><E><D><S><L><Y><L><G><G><E><W><Q><F><N><H><F><S><K><L><T><S><S><R><P><D><A><A><F><A><E><I><Q><R><T><S><L><P><E><K><S><P><L><S><C><E><T><R><V><D><L><C><D><D><L><A><P><V><A><R><Q><L><A><P><R><E><K><L><P><L><S><S><R><R><P><A><A><V><G><A><G><L><Q><N><M><G><N><T><C><Y><V><N><A><S><L><Q><C><L><T><Y><T><P><P><L><A><N><Y... | Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.<BOP> | D6RCP7 |
Q96D46 | NMD3_HUMAN | 60S ribosomal export protein NMD3 | Homo | <M><E><Y><M><A><E><S><T><D><R><S><P><G><H><I><L><C><C><E><C><G><V><P><I><S><P><N><P><A><N><I><C><V><A><C><L><R><S><K><V><D><I><S><Q><G><I><P><K><Q><V><S><I><S><F><C><K><Q><C><Q><R><Y><F><Q><P><P><G><T><W><I><Q><C><A><L><E><S><R><E><L><L><A><L><C><L><K><K><I><K><A><P><L><S><K><V><R><L><V><D><A><G><F><V><W><T><E><P><H><S... | Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.<BOP> | Q96D46 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.