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Liver Cell Biology Research Group(LIVR)
Brussels Health Campus • Vrije Universiteit Brussel • Brussels • Belgium
Mission
Advance understanding of liver cell diversity, regeneration and fibrosis to drive novel biomarkers, in vitro disease models and therapeutic strategies for chronic liver disorders.
Research Objectives
- Cellular Characterization
Profile healthy vs. diseased liver cell types at single‑cell resolution. - Fibrosis Mechanisms
Dissect pathways of hepatic stellate cell activation, fibrogenesis and resolution. - Biomarker Discovery
Identify stellate‑cell‑specific markers for non‑invasive fibrosis staging. - Disease Modeling
Build iPSC‑derived liver cell co‑cultures and organoids to recreate MASLD and other chronic conditions. - Regeneration & Progenitors
Elucidate the role of liver progenitor cells in tissue repair.
Key Collaborations & Networks
- ImAgE‑D (Marie Skłodowska‑Curie ITN, Oct 2023 – Sep 2027)
High‑speed, super‑resolution imaging of endothelial and liver cells. - DeLIVERy (EIC Pathfinder, May 2022 – Apr 2026)
Personalized polypharmacy testing on patient‑derived mini‑livers.
Publications & Resources
- Latest Publications
- JHEP Reports: “HSC single‑cell atlas reveals activation across etiologies”
- Biofabrication: “iPSC‑derived liver spheroids to model fibrosis”
- Science: “Hippo signaling instructs ectopic organ growth”
- Full Publication List:
Browse all publications (2010–present) Research Portal Click here.
Team & Training
- Current Members | Former Members
Explore profiles and roles on our Team page. - Doctoral & Post‑doc Training
Interactive workshops, imaging courses, and 3R‑principle seminars for early‑career researchers.
News & Events
- Belgian Stem Cell Meeting – Nov 28 2025 @ ULB Erasme Campus
- Upcoming Seminars & “Film Nights” showcasing 3R approaches and mini‑liver therapies
- Follow live updates in News & Events.
Contact
Laarbeeklaan 103, Building D – Room D022
1090 Brussels, Belgium
jmlazou@vub.be | +32 2 477 4409
“By unlocking liver cell biology, we pave the way for precision therapies in chronic liver disease.”