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Breast cancer is the most commonly diagnosed cancer among women and has the second highest mortality rate after lung cancer. "Since the establishment of a breast cancer screening program in Canada beginning with British Columbia in 1988 and followed by the other Canadian provinces over the following ten years, breast c... | New Brunswick (NB) Canada uses its breast cancer screening service program to assess the extent to which eligible NB women are complying with mammography guidelines.While many studies have investigated factors associated with participation in periodic breast cancer screening in Canada and elsewhere, most work has relie... |
those recently arrived women who did participate, they were also more likely to continue to comply with the guidelines after joining the program.One apparently anomalous result is urban/rural status.Women living in medium cities or rural areas were less likely to have participated in screening upon turning 50 than wome... | Using a longitudinal administrative dataset for NB over the period 1996–2011 of 255,789 eligible women aged 45–69, this study examined demographic, socioeconomic and geographic factors associated with initial participation in regular screening at age 50 and ongoing retention in the program.Logistic regression was used ... |
Understanding family firms is an important area of investigation in management research and economics .The German economy is a suitable setting to analyze such businesses, given that it is largely shaped by small and medium sized enterprises, which are quite often family owned.Equally, many larger corporations headquar... | It includes data on five dimensions of entrepreneurial orientation (innovativeness, proactiveness, risk taking, autonomy, competitive aggressiveness), three dimensions of long-term orientation (futurity, perseverance, continuity), six dimensions of stewardship climate (organizational identification, collectivist orient... |
and a link to a web-based survey were sent by email to the owners and/or CEOs of the firms identified.To mitigate ethical concerns in survey research, we aimed at protecting research participants by providing full transparency on the purpose and motivation of the research and ensuring the anonymity of research particip... | This data article describes a dataset of 208 cases representing assessments of entrepreneurial orientation and organizational culture variables obtained from a web-based survey addressing owners and/or CEOs of German family firms.Additionally, firm-level attributes (e.g., industry, age, size) and top management-level c... |
presence of LSOPC, the inhibition ratios were 69.58 ± 5.60%, 18.80 ± 2.88% and 96.18 ± 1.50%.Fig. 7 shows the influences of metal ions on the formation of AGEs with and without LSOPC when heated at 80°C for 2 h under pH 6.5.The inhibition effects of most metal ions did not change compared to that heated at pH 5.0.Howev... | Therefore, it is of interest to monitor AGEs in food processing.The present study was carried out to investigate the influence of lotus seedpod oligomeric procyanidin (LSOPC) concentrations, solution pH value and metal ions on AGE formation by heat treatment of lactose-lysine model solutions.Nε-(carboxymethyl) lysine (... |
Originally proposed by Deoni et al., “multicomponent driven equilibrium steady-state observation of T1 and T2” is the multi-component adaptation of the established driven-equilibrium single-pulse observation of T1, also called the Variable Flip Angle method, and T2 techniques that enable accurate and precise determinat... | Multicomponent driven equilibrium steady-state observation of T 1 and T 2 (mcDESPOT) aims to quantify the Myelin Water Fraction (MWF) using a two-pool microstructural model.The MWF has been used to track neurodevelopment and neurodegeneration and has been histologically correlated to myelin content.mcDESPOT has a clini... |
the PAR1-activating peptide.Furthermore, this response was prevented by inhibiting TGF-β signaling using SB431542.Since PAR1 knockdown or deletion activated TGF-β signaling and thereby reduced the generation of ECs, we next addressed the effects of PAR1 activation.Here, surprisingly, we observed that PAR1 activation al... | We observed that either deletion or activation of PAR1 suppressed mouse embryonic stem cell (mESC) differentiation to ECs and neovascularization in mice.This was mediated by induction of TGFβRII/TGFβRI interaction, forming an active complex, which in turn induced SMAD2 phosphorylation.Thus, PAR1 in its inactive unligat... |
To flexibly and efficiently reason about temporal sequences, abstract representations that compactly represent the important information in the sequence are needed.One way of constructing such representations is by focusing on the important events in a sequence.In this paper, we propose a model that learns both to disc... | We propose a model that learns to discover informative frames in a future video sequence and represent the video via its keyframes. |
Microcystis is a genus of freshwater cyanobacteria that is frequently found in meso- to eutrophic waters.Their phylum originated some 3 billion years ago , and their photosynthetic activity prompted the oxidation of the Earth’s atmosphere .Throughout time they have successfully adapted to extreme environments through p... | Through batch culture studies, we yielded microcystins at concentrations that are environmentally relevant to freshwaters around the world (1–300 μg L−1), maintained these concentrations without resupplying fresh medium (further reducing costs), and utilized rate equations to model the relationship between the environm... |
and -microcystin-LR were present in samples, the ratio of microcystin-LR would be greater because atmospheric carbon exchange was abundant.Results confirmed the presence of both microcystin congeners across the samples received, and found the concentration of microcystin-LR was higher than -microcystin-LR after quantif... | Microcystis aeruginosa is a cosmopolitan cyanobacteria that continues to jeopardize freshwater ecosystem services by releasing the hepatotoxin microcystin, which can, in some cases, cause death to aquatic fauna and even humans.Currently, our abilities to understand the mechanisms of microcystin toxicology are limited b... |
The sea cucumber I. badionotus, is a resource of great economic importance for the south-east region of the Gulf of Mexico and Central American and Caribbean countries.The demand in the international market, mainly from the Asian countries, has increased, with prices per kg of the dry salty product ranging from USD 203... | Isostichopus badionotus is a sea cucumber species of great ecological and economic relevance for Mexico and Central American and Caribbean countries; however, the protocols for the extraction of the nucleic acids have not yet been published.In this study, we describe the first protocols to obtain DNA and RNA from diffe... |
Reagent was added to the sample and vigorously vortexed until it was completely homogenized.The samples were then incubated over night at 4 °C.Subsequently, they were centrifuged at 13,000 rpm for 10 min at 4 °C.The samples, in which separation of phases was not observed, were centrifuged for an additional 10 min.The s... | The methodologies used in this study allowed us to obtain DNA and RNA of high quality and integrity in the different tissues of I. badionotus, which will be the basis for future genomic and transcriptomic studies.The successful extraction of DNA and RNA was achieved in the different tissues of I. badionotus.The concent... |
conduct.This leads to the question whether the others might be in need of similar arrangements, of the same ambition advocated for quantitative research by.Scholars trained in the use of numbers have the mental habit of questioning their solidity.The same concept is not absent from popular culture.When Homer Simpson sa... | Something can be gained by looking at common ethical features of different instances of quantification.While ethics of algorithms is perceived at present as an urgent issue, similar concerns can easily be associated to the use of metrics, of statistical inference, and of mathematical modelling.By reviewing these common... |
Scholars have found school canteens to be a relevant source of food waste, which is a growing ethical, environmental and economic problem ."Collecting and analysing data on school sustainability initiatives in general - and food waste management in particular - are interesting tasks to define, measure and rank the scho... | This paper presents data from a survey administered to 548 public and private school headteachers in Catalonia (Spain) in 2018 on sustainability practices and food waste management.Raw data were collected through a standardised and structured questionnaire (For more information refer to Building and managing sustainabl... |
20 was used to blank the spectrophotometer.The ferric reducing power assay outlined by Lim et al. was used to determine the ability of crude plant extracts to reduce the Fe3 +/ferricyanide complex to the ferrous form.Using a 96 well microtitre plate, 30 μl of methanolic plant extract, ascorbic acid or BHT was serially ... | Out of a total of 53 evaluated extracts, significant anti-inflammatory activity was observed in nearly 40% of extracts in the COX-1 assay and 25% of extracts in the COX-2 assay.Overall, the DCM root extract of Ansellia africana was the most potent, the DCM tuber extract of Eulophia hereroensis was the only extract to s... |
medicinal plant sources in Indian traditional medicine.Simmler et al. evaluated the skin photoprotective effect of Vanda coerulea stilbenoids based on the widespread use of orchid extracts in the cosmetic industry.Ultraviolet-induced damage often results in oxidative stress and associated inflammatory processes.Ultravi... | Bulbophyllum scaberulum DCM root extract was also the most effective anti-cholinesterase extract, performing better than galanthamine.In the single electron transfer (SET) (2,2'-diphenylpicrylhydrazyl (DPPH) free radical scavenging assay and ferric reducing antioxidant power (FRAP) reaction based assays, E. petersii ps... |
the substance.Elgorashi et al. reported on the possible mutagenic effects of 51 South African medicinal plant species.Reid et al. evaluated 42 other South African species.There has been extensive research into the mutagenic and anti-mutagenic potential of medicinal plants used in the South African traditional medical s... | While the role of various processes in inflammatory-related degenerative disorders is still being researched, many avenues of research have concentrated on the treatment and/or prevention of these disorders.Organic leaf and root extracts of C. arcuata produced no genotoxic effects in comparison to the other tested spec... |
According to the Union of Concerned Scientist, at the end of January 2015, there were 192 Earth observation satellites in orbit measuring different Earth parameters and generating, together with a myriad of other sensors and monitoring systems, huge volumes of geospatial data.The large and diverse Earth science data, o... | Provenance, a metadata component referring to the origin and the processes undertaken to obtain a specific geographic digital feature or product, is crucial to evaluate the quality of spatial information and help in reproducing and replicating geospatial processes.In particular, W3C PROV is applied to feature models, w... |
feature.If the target feature does not exist in the source dataset, a new empty feature is created according to the schema of the source dataset.Attributes of new features subject to a conflation rule are accordingly mapped against an attribute of the original feature or set to a fixed value.All other attribute values ... | However, the heterogeneity and complexity of the geospatial processes, which can potentially modify part or the complete content of datasets, make evident the necessity for describing geospatial provenance at dataset, feature and attribute levels.attributes.Next, an approach for applying the generic W3C PROV provenance... |
For obtaining mechanical properties of thermoplastic composites fabricated using recycled wind turbine blade materials, flexural tests were performed based on ASTM D790-17.We determined the influence of refined particle size, resin content and coupling agents and methacryloxypropyltriethoxysilane) on the mechanical pro... | The wind turbine blades (WTB) that face end-of-life was first mechanically milled and classified through a range of varying screen sizes.We then blended this with high density polyethylene (HDPE) thermoplastic resin and extruded it to a profiled composite.We determined the influence of refined particle size, resin cont... |
Protein expression levels of Drosophila melanogaster embryos were monitored by SWATH-MS after heat-shock treatments.Proteins were extracted from embryos using a total lysis with a buffer containing 4% SDS.Samples were prepared using a GeLCMS preparation method and proteins were digested with trypsin.HRM peptides were s... | Data independent acquisition (DIA) has emerged as a promising mass spectrometry based approach, combining the advantages of shotgun and targeted proteomics.Here we applied a DIA approach (termed SWATH) to monitor the dynamics of the Drosophila melanogaster embryonic proteome upon heat-shock treatment.Embryos were incub... |
signal from other clusters within a 2-dimensional histogram in a multiplex assay.The insufficient separation of clusters leads to lower sensitivity due to false positives.In fact, the fluorescence cluster associated with the assays for L858R has a limited space between the cluster associated with the assays for an exon... | Epidermal growth factor receptor (EGFR) mutations have been used as the strongest predictor of effectiveness of treatment with EGFR tyrosine kinase inhibitors (TKIs).Three most common EGFR mutations (L858R, exon 19 deletion, and T790M) are known to be major selection markers for EGFR-TKIs therapy.Here, we developed a m... |
the interstitial clusters will migrate one-dimensionally along 〈1 1 0〉 directions; however, they were found to change orientation leading to 3-D migration along several 〈1 1 0〉 type directions.The authors reported that in a 20 ns simulation the average distance travelled along a 〈1 1 0〉 direction was 1 nm before rotati... | Here we study He ion irradiation of pure Ni and two equiatomic concentrated solid-solution alloys (CSAs) of FeNi and FeCrNiCo.It is expected from the significantly reduced diffusion of SIAs in CSAs, including high entropy alloys (HEAs), that long range anisotropic SIA migration cannot be active.The ion dose and flux re... |
in monogamous taxa or in nonfertilising sperm.Combinations of these experimental and comparative approaches could be used and will be revealing because predictions for the possibilities outlined are reasonably distinct and readily testable.Sperm are loaded with RNAs.To date, functionality has been ascribed to a few of ... | Classically, sperm were seen as transcriptionally inactive vehicles for delivering the paternal haplotype to an egg.Yet, it has become apparent that sperm also carry thousands of different RNAs, and the functions of most of these are unknown.Here, we make four novel suggestions for sperm RNA function.First, they could ... |
from more disparity."Kanchanaburi's Demographic Surveillance System presents a unique opportunity to study the prospective relationship of wealth inequality and health outcomes.Kanchanaburi is a large province in western Thailand and the only one in the country which has a DSS, comprising a longitudinal census for moni... | A population-based cohort study with a one-year follow-up was nested in a Demographic Surveillance System (DSS) of 100 villages in western Thailand.Data were drawn from a random sample of 1104 older residents, aged 60 or over (one per household) drawn from all 100 villages, of whom 982 (89%) provided problem drinking d... |
study lay in the utilization of the fact that high wealth inequality and the continuing rise in wealth inequality were particularly prominent in many developing nations.Another advantage was that the older populations in the present study were largely local and rarely migrated, as opposed to younger adults, hence loss ... | Evidence on the link between income inequality and alcohol-related problems is scarce, inconclusive and dominated by studies from the developed world.The use of income as a proxy measure for wealth is also questionable, particularly in developing countries.The goal of the present study is to explore the contextual infl... |
is largely due to farmers having already harvested before the team reached a village, or the crop not yet having ripened at the time the team reached a village.Active participation in the project appears unrelated to observable farmer, household, or farm characteristics, and also differences between farmers with and wi... | A pilot implementation in the rice-wheat belt of India speaks to PBI being a feasible and valuable innovation to reduce downside basis risk in index insurance: nearly two-thirds of trained farmers took at least four pictures (roughly one per growth stage), which was considered sufficient for loss assessment; severe dam... |
HA-coated surface showed evidence of hemidesmosomal adherence, indicative for the presence of basal keratinocytes.Collagen IV was present around cells on the surface of the HA-coating, which indicates the formation of a basement membrane.In one of the cases a high degree of tissue organization was achieved, with vascul... | Upon integration, the host's ability to cover the abutment surface (“race for the surface”), and thus control and prevent competitive bacteria from colonizing it, is improved.However, the attachment mechanisms behind it are not clear.Evidence of skin integration was found, including the presence of hemidesmosomes, a ba... |
heterogeneous populations over time.Similar loss in DSC signal or ΔH’ of unfolding has been reported for recombinant botulinum neurotoxin adsorbed to AH after storage at 30°C for 9 weeks.50,Furthermore, protein structural changes on the surface of aluminum could lead to stronger adsorption over time, which in fact was ... | A nonreplicating rotavirus vaccine (NRRV) containing 3 recombinant fusion proteins adsorbed to aluminum adjuvant (Alhydrogel [AH]) is currently in clinical trials.The compatibility and stability of monovalent NRRV antigen with key components of a multidose vaccine formulation were examined using physicochemical and imm... |
and assessor blinding is not specified."Van Gent, Vida, & Zwart's N = 34 study compares group psychoeducation to a WL control condition, method of allocation not specified.Anxiety symptoms were unchanged, and psychoeducation did not reduce anxiety compared to WL control condition.Data from the treatment described in th... | Comorbid anxiety is common in bipolar spectrum disorders [BPSD], and is associated with poor outcomes.This article reviews evidence for the effectiveness of psychological therapy for anxiety in adults with BPSD (bipolar I, II, not otherwise specified, cyclothymia, and rapid cycling disorders).A systematic search yielde... |
of injured pedestrians turned out to have a great influence, whereas variations in the speed had a medium impact, and variations in the percentage of pedestrians sharing a social identity had a relatively small impact.Since the latter parameter is very hard to measure, this is encouraging news for the safety scientist ... | Social scientists have criticised computer models of pedestrian streams for their treatment of psychological crowds as mere aggregations of individuals.Indeed most models for evacuation dynamics use analogies from physics where pedestrians are considered as particles.Although this ensures that the results of the simula... |
for all samples doped.At the 3% Sr-doping, the blue emission disappeared completely and the red emission was at the lower intensity).The intensity of PL signal enhanced again for 4% and 5% Sr doping concentrations.This is in full agreement with the results observed from the XRD, AFM and uv–vis measurements.The Sr dopin... | Pristine and strontium doped ZnO nanometric films were successfully synthesized on heated glass substrates by the ultrasonic spray pyrolysis technique.The samples were characterized by means of X-ray diffraction (XRD), Atomic Force Microscope (AFM), UV–visible spectroscopy and photoluminescence (PL).X-ray diffraction p... |
type shown in Fig. 19a, was presented in the TEM image in Fig. 17, which shows fragments of aluminium oxide dispersed along a AA1050 roll bonded weld line.In this work a new model of bonding strength is presented which, building on the well-known work by Bay, takes account of all the relevant deformation parameters in ... | Solid bonding of aluminium is an important joining technology with applications in fabrication, forming and new low-carbon recycling routes.The influence of deformation conditions on the strength of the resulting weld has yet to be fully assessed, preventing optimization of current processes and development of new ones... |
same results as those from conventional numerical simulator.In addition, as mentioned in Section 2.5, Morven has the ability to simulate models described by any general DAEs, which have to be converted to ODEs in order for conventional numerical simulators to use them.Results obtained from the semi-quantitative simulat... | In this paper we demonstrate how Morven, a computational framework which can perform qualitative, semi-quantitative, and quantitative simulation of dynamical systems using the same model formalism, is applied to study the osmotic stress response pathway in yeast.We then built a qualitative model for the biophysical pro... |
differed between GAC and sand packed columns.In GAC columns, removal started high at 40%, due to DOC adsorption, but dropped after 19 days stabilising at an average of 15%.The stable DOC removal from day 25 onwards is most likely due to biological activity compared to the chemical/physical adsorption that occurred in t... | Little is known about the forces that determine the assembly of diverse bacterial communities inhabiting drinking water treatment filters and how this affects drinking water quality.This study investigates the development of the microbial community on two common contrasting filter materials (quartz sand and granular ac... |
The abnormal toxicity test, also referred to as General Safety Test or test for innocuity, is carried out in mice and guinea pigs, and is supposed to detect non-specific contaminants and toxins that may be present in the final product.The laboratory animal batch safety test is comparable to ATT, and required for veteri... | This one-day symposium organized by Humane Society International (HSI) brought together 18 international experts from Argentina, Brazil, China, Europe, India, Russia, South Africa and the United States to discuss the elimination of the abnormal toxicity test (ATT) from the testing requirements for human vaccines as wel... |
and effective products for prevention and care with very limited financial and technical resources at their disposal.It was noted that the initial cost of establishing, validating and implementing a new in vitro method to replace an in vivo test will be more than offset in the long run by savings in cost associated wit... | Participants reported on country-specific regulatory requirements and, where present, the perspectives on waiver and elimination of those tests.In addition, the attendees, with HSI in the role of facilitator, moved to define the barriers to the complete elimination or waiving of these tests.This report expounds the out... |
past, researchers monitored wildlife using cameras from which they would manually extract the data.This is a time-consuming and labor-intensive approach.Prior research has utilized location and other contact details to be collected by using motes embedded in collars of animals.VECTORS can help simplify this labor-inten... | Crowd-sourced video distribution is frequently of interest in the local vicinity.In this paper, we present a software platform called VECTORS to transfer videos over opportunistic networks with adaptive quality encoding to achieve reasonable delay bounds.The video segments are transmitted between source and destination... |
plant density might be one reason for high nematode incidences.The number of other crops intercropped was high, we found mixtures of taro, sweetpotato, cassava, eggplant, pumpkin, coconut, and orange cardamom and weed control was poor.Weeds such as Bermuda grass, nut grass and black nightshade are also host to differen... | Pratylenchus coffeae is among the plant parasitic nematodes contributing to yield losses of banana.To determine the status of P. coffeae, a survey was conducted in banana-growing regions of Tanzania and samples collected.The results indicated that in 2015 there was an increase in total counts of P. coffeae extracted fr... |
portion was not significantly different from zero and so was fixed as such.Also, there was no effect of storage on any of the other parameters in the model with separately estimated values for each of them being non-significant.There was, however, an effect of site for both a and b parameters, but crucially not for the... | Acrylamide is produced from free asparagine and reducing sugars during high-temperature cooking and food processing, and potato products are major contributors to dietary acrylamide intake.The present study analysed twenty varieties of potatoes grown at two sites (Doncaster and Woburn) in the United Kingdom to assess t... |
were taken using ten spindles in total from three embryos.A χ2 analysis was undertaken to assess correlations in the distribution of the comet directions.Spindle length comparisons between cycling control, d-tpx2/mei-381, and marsp embryos were undertaken by manually drawing a line from the center of each pair of centr... | Although different cells have been shown to use different molecular pathways to generate the microtubules required for spindle formation, how these pathways are coordinated within a single cell is poorly understood.We have tested the limits within which the Drosophila embryonic spindle forms, disrupting the inherent te... |
to depth or width requirements or acceptable designs limited by construction materials availability.The introduction and implementation of various constitutive models for three emerging construction materials namely: UHPC, HSS, and large prestressing strands is provided in this paper.The validity of the proposed materi... | MC-BAM is a software for moment–curvature section analysis of beams.It is developed to facilitate the analysis and structural design of beams and girders with advanced construction materials like ultra-high performance concrete (UHPC), high strength steel rebars and/or large prestressing strands.MC-BAM supports several... |
science to its values without apparent regard for those of medicine, have begun to make regulatory changes to enable greater responsiveness to health consumer need and so draw their citizens back within the hegemonic boundaries.In many ways, the biomedical innovation hegemony is static, embedded in the fortress of prof... | The global political economy of stem cell therapies is characterised by an established biomedical hegemony of expertise, governance and values in collision with an increasingly informed health consumer demand able to define and pursue its own interest.How does the hegemony then deal with the challenge from the consumer... |
ROI mapping, as this was performed using the simplifying assumption that the CMOS centre is a reliable indicator of head orientation.Having to follow a clearly defined procedure through the necessity to complete the incident log ensured that despite heterogeneous sampling approaches, subgoal completion remained structu... | Road traffic control rooms rely on human operators to monitor and interact with information presented on multiple displays.Past studies have found inconsistent use of available visual information sources in such settings across different domains.In this study, we aimed to broaden the understanding of observer behaviour... |
The consumptions of edible mushrooms as a component of healthy human diet are increasing worldwide.Edible mushrooms contain basic nutrients, high proteins, vitamins as well as minerals required for human growth and development.Edible mushrooms have also been reported to have medicinal properties.Agaricus blazei Murill,... | Spawns of mushroom Agaricus bisporus (white button and crimini varieties) mixed with chicken composted manures sponsored by a certified supplier in Pretoria were spread on polluted soil and allowed to grow to maturity under a controlled environment for mushrooms before harvesting.Harvested mushrooms were separated into... |
microwave digestion system.The resulting solution was then made up to volume by adding deionized water to the digested sample and analysed for trace metal content using inductively coupled plasma mass spectrometry to determine the concentrations of individual trace metals.Each determination was done in triplicate.Data ... | The concentrations of trace metals in the mushrooms were in the ranges of 0.63 ± 0.07 μg/g–370.4 ± 4.71 μg/g Cr, 6.84 ± 0.32 μg/g–492 ± 1.79 μg/g Mn, 0.08 ± 0.03 μg/g–16.37 ± 6.43 μg/g Co, 1.19 ± 0.17 μg/g–54.12 ± 2.70 μg/g Ni, 16.75 ± 0.34 μg/g–51.30 ± 2.91 μg/g Cu, 39.71 ± 0.41 μg/g–257.95 ± 2.38 μg/g Zn and 0.24 ± 0... |
0.03 μg/g–16.37 ± 6.43 μg/g, and the highest concentration was recorded in the stalks of crimini mushrooms from soils collected from site D.Cobalt values in the literature have been reported in the ranges of 0.28–1.32 μg/g by Tuzen, 0.12–0.62 μg/g by Sesli and Tuzen and 0.15–6.03 μg/g by Isiloglu et al., respectively.T... | Consumption of mushrooms is believed to assist in supplying basic nutrients that are required for human growth and well-being maintenance.It has been noted that vegetables and other agricultural crops may uptake trace metals from polluted soils.The present study investigated the pattern and concentrations of trace meta... |
Many machine learning algorithms represent input data with vector embeddings or discrete codes.When inputs exhibit compositional structure, it is natural to ask whether this compositional structure is reflected in the the inputs’ learned representations.While the assessment of compositionality in languages has received... | This paper proposes a simple procedure for evaluating compositional structure in learned representations, and uses the procedure to explore the role of compositionality in four learning problems. |
Forest and woodland resources play a key role in rural livelihoods in developing countries.Over 2.7 billion people worldwide are estimated to depend on woodfuel for their primary energy needs, and woodfuel is just one component of an often under-recognised ‘hidden harvest’ of environmental resources also comprising agr... | Forest and woodland resources can play a key role in rural livelihoods in the Global South, making it critical to understand what forest change could mean for rural wellbeing.Calculating environmental income has become a popular method of highlighting the importance of environmental resources in livelihoods, but few st... |
will motivate further research.The first limitation is the single-year time frame used in this study.The high environmental dependence observed in this study may be partially attributable to the fact that research was carried out in a drought year, also explaining why field crop income accounts for on average only 3.1%... | The objective of this study was therefore to explore links between woodland cover, provisioning ecosystem service availability and household environmental income by applying a novel interdisciplinary approach in six villages on a gradient of woodland resource availability in Zimbabwe.We firstly use techniques from quan... |
as target organisms.An ideal natural product antifouling compound will act different ways on the target organisms.Generally, the compound should prevent the formation of biofilms, which is considered as a cue for the further settlement of invertebrate larvae in the marine environment.The extracts or compounds from the ... | In the marine environment, all hard surfaces including marine macroorganims are colonized by microorganisms mainly from the surrounding environment.The microorganisms associated with marine macroorganisms offer tremendous potential for exploitation of bioactive metabolites.Biofouling is a continuous problem in marine s... |
to develop any special business models for emerging markets.Rather, they should integrate local situation-specific knowledge to existing structures over time to maintain a “dynamic” balance."In this regard, AVM's higher-frequency strategic planning process implemented in China offers a typical example of how a dynamic ... | Dynamic capabilities are arguably of more value in the internationalization process, particularly of multinational companies (MNCs) that operate in highly dynamic international markets.Yet there is a scarcity of research on the nature of dynamic capabilities in such highly relevant contexts.This exploratory study prese... |
create potent and selective antagonists of C5a1 led to only partial agonists.This may be due to the fact that most potent peptides had a mutation of Gly to Pro at position 73, disrupting the turn conformation of the C-terminus.Researchers at Merck were some of the first to succeed in creating a small peptide inhibitor ... | The complement cascade is a highly sophisticated network of proteins that are well regulated and directed in response to invading pathogens or tissue injury.Complement C3a and C5a are key mediators produced by this cascade, and their dysregulation has been linked to a plethora of inflammatory and autoimmune diseases.Co... |
While the participants worked with mathematics tasks described in section 2, eye-fixations and dwell time were recorded.Mean values of these variables as presented in the supplementary Excel file."Participant scores on Raven's Advanced Progressive Matrices and Operation Span are also included, as well as mathematical p... | This data article contains eye-tracking data (i.e., dwell time and fixations), Z-transformed cognitive data (i.e., Raven's Advanced Progressive Matrices and Operation span), and practice and test scores from a study in mathematics education.This data is provided in a supplementary file.The method section describes the ... |
operational flexibility with lower investments.However, despite the co-firing industry being a front-runner of torrefaction research, there is little available data about current use of torrefied pellets in industrial applications, and limited knowledge of its implementation in industries such as the chemical and petro... | Wood pellet imports are expected to increase in the European Union and Southeast Asia by 2030, considering pellets are the main feedstock used for co-firing in power plants throughout these regions.Due to the material's physical and biological properties, the equipment at an import terminal need to be different than wh... |
Prediction of ash deposition formation is of great importance in the efficient utilisation of various solid fuels and the development of combustion technologies .Predicting the particle sticking efficiency is a critical step in modelling the ash deposition formation, which is dictated by the ash chemistry, particle pro... | The tendency of ash particles to stick under high temperatures is dictated by the ash chemistry, particle physical properties, deposit surface properties and furnace operation conditions.The model incorporates the particle properties relevant to the ash chemistry, particle kinetic energy and furnace operation condition... |
al. , and other properties are estimated based on the ash composition, as shown in Table 2 .Since there is no experimental data on the contact angle, a value of 135° is used in the current study, which produces a good correlation with the measurements of the deposition rate.An uncertainty study of the contact angle ran... | A model has been developed in order to predict the particle sticking efficiency for fly ash deposition at high temperatures.The furnace velocity condition has been identified as being able to influence the selective deposition behaviour, where the maximum deposition efficiency moves to smaller particles when increasing... |
with increasing the gas velocity.Figure 8 shows the deposition efficiency as a function of particle size under different gas velocity conditions.The maximum deposition efficiency gradually changes from the coarse particle size region in the low gas velocity condition to the medium/small particle size region in the high... | Compared with the measurements, the proposed model presents reasonable prediction performance on the particle sticking behaviour and the ash deposition formation.Through a sensitivity analysis, furnace operation conditions (velocity and temperature), contact angle and particle size have been found to be the significant... |
The biggest improvement in timekeeper accuracy was due to the introduction of the oscillator as a time base, first the pendulum by Christiaan Huygens in 1656 , then the balance wheel-spiral spring by Huygens and Hooke in about 1675, and the tuning fork by N. Niaudet and L.C. Breguet in 1866 .Since that time, these have... | In previous work, we showed that two degree of freedom oscillators can be advantageously applied to horological time bases since they can be used to eliminate the escapement mechanism.We subsequently examined planar two degree of freedom oscillators based on parallel flexure stages.We noted that these oscillators are s... |
oscillator respect Listing's law, which is well-known to apply to human eye movement. "We analyze the kinematics and dynamics of spherical rotation under Listing's law.We will show that the dynamics are essentially that of a point mass, i.e., condition 5 above.We then examine potentials corresponding to central restori... | In order to restrict spherical rotation to two degrees of freedom, we restrict the kinematics to obey Listing's law, a well-known constraint occurring in human eye movement.We show that a particular central restoring force we call the scissors law is best suited for chronometric performance and propose a number of theo... |
acid across the cell membrane, which acidifies the cytoplasm and reduces the proton motive force .The threshold concentration of formate above which growth is inhibited seems to be, at least to some extent, affected by the activity of formate dehydrogenase.Microorganisms that endogenously have only weak formate dehydro... | Methanol and formate are attractive microbial feedstocks as they can be sustainably produced from CO2 and renewable energy, are completely miscible, and are easy to store and transport.Here, we provide a biochemical perspective on microbial growth and bioproduction using these compounds.We show that anaerobic growth of... |
at 60–64 years.We used a composite score to describe the number of adverse hormone concentrations—similar composite scores have been shown to be more strongly related to frailty risk than single hormone measures, but they are clearly simplifications of a dynamic, interactive endocrine system, and their construction is ... | Background: Little is known about how socioeconomic position (SEP) across life impacts on different axes of the endocrine system which are thought to underlie the ageing process and its adverse consequences.We examined how indicators of SEP across life related to multiple markers of the endocrine system in late midlife... |
on tissue-specific mQTLs is still sparse.One strategy to maximise the interpretability of EWAS projects is to examine DNAm as a biomarker for mental health problems that have mechanistic underpinning in tissues other than the brain, such as blood.A wide-range of psychiatric disorders have been associated with immune fu... | The recent interest in epigenetics within mental health research, from a developmental perspective, stems from the potential of DNA methylation to index both exposure to adversity and vulnerability for mental health problems.Genome-wide technology has facilitated epigenome-wide association studies (EWAS), permitting ‘h... |
adducts.However, we found no significant differences in BP-DNA adduct levels between BP treated samples and samples that were additionally treated with IL-8.We examined whether this could be explained by the induction of DNA repair that counterbalances the increased formation of DNA adducts.Indeed, we observed a 3-fold... | It has been well established that inflammation and concurrent mutagenic exposures drive the carcinogenic process in a synergistic way.To elucidate the role of the inflammatory cytokine IL-8 in this process, we studied its effect on the activation and deactivation of the chemical mutagen benzo[a]pyrene B[a]P in the immo... |
Increasing model size when pretraining natural language representations often results in improved performance on downstream tasks.However, at some point further model increases become harder due to GPU/TPU memory limitations, longer training times, and unexpected model degradation.To address these problems, we present ... | A new pretraining method that establishes new state-of-the-art results on the GLUE, RACE, and SQuAD benchmarks while having fewer parameters compared to BERT-large. |
Neointimal hyperplasia limits the long-term durability of vascular interventions such as balloon angioplasty, stenting, endarterectomy, and bypass grafting.Current FDA approved drug eluting stents, designed to prevent the development of neointimal hyperplasia, deliver derivatives of two different classes of drugs, both... | Background: Nitric oxide (.NO) is more effective at inhibiting neointimal hyperplasia following arterial injury in male versus female rodents, though the etiology is unclear.Given that superoxide (O2.-) regulates cellular proliferation, and .NO regulates superoxide dismutase-1 (SOD-1) in the vasculature, we hypothesize... |
no significant increase in expression in females occurred with DETA/NO over 12 h.These data suggest sod-1 gene expression in VSMC depend on sex and that •NO has differential effects on regulating sod-1 gene expression in male versus female VSMC.Given the differential effect on sod-1 transcription between the sexes at b... | SOD-1, SOD-2, and catalase protein levels were detected by Western blot.Results: In vitro, male VSMC have higher O2.- levels and lower SOD-1 activity at baseline compared to female VSMC (P<0.05).NO decreased O2.- levels and increased SOD-1 activity in male (P<0.05) but not female VSMC.NO also increased sod-1 gene expre... |
increasing the availability of tetrahydrobiopterin, preventing eNOS uncoupling and ROS generation .Stirone et al. showed that estrogen can increase eNOS gene expression while McNeill et al. demonstrated increased eNOS protein levels in endothelial cells and VSMC with 17β estradiol treatment .Arias-Loza et al. demonstra... | These data suggest that sex-based differential redox regulation may be one mechanism by which .NO is more effective at inhibiting neointimal hyperplasia in male versus female rodents. |
The folding structure of the DNA molecule combined with helper molecules, also referred to as the chromatin, is highly relevant for the functional properties of DNA.The chromatin structure is largely determined by the underlying primary DNA sequence, though the interaction is not yet fully understood.In this paper we d... | A method to transform DNA sequences into 2D images using space-filling Hilbert Curves to enhance the strengths of CNNs |
for both the volume of and white matter hyperintensity presence within frontal and basal ganglia regions to influence gait velocity, although many brain regions have been related to gait velocity in some capacity.Beyond this our conclusions are more limited, largely due to the small range of discrete gait characteristi... | Gait is complex, described by diverse characteristics underpinned by widespread central nervous system networks including motor and cognitive functions.Despite this, neural substrates of discrete gait characteristics are poorly understood, limiting understanding of gait impairment in ageing and disease.This structured ... |
TEER results and increased concentrations of pro-inflammatory cytokines.Interestingly, neither of these points can explain the TEER reduction reported by Kanzato et al.Compared to this work, Kanzato and colleagues used a lower macrophage density and refrained from differentiating the THP-1 cells."In combination with th... | Inflammatory conditions can significantly change the normal functioning of the intestine.In vitro models that adequately reproduce both healthy and inflamed intestinal tissue could provide a useful tool for studying the mechanisms of intestinal inflammation and investigating new therapeutic drugs.In these conditions a ... |
others in vitro.The control exerted by the Caco-2 cells could be bypassed by pre-exposing THP-1 cells to LPS in advance of the co-culture and integrating IFN-γ in the system through Caco-2 barrier-priming with IFN-γ and IFN-γ-stimulation of THP-1 cells.Wang et al. showed that ‘priming’ of Caco-2 cells with IFN-γ induce... | We established a co-culture of Caco-2 and PMA-differentiated THP-1 cells that mimics the intestine in healthy and controlled inflamed states.To simulate the inflamed intestine, the Caco-2 barrier was primed with IFN-γ and THP-1 cells were pre-stimulated with LPS and IFN-γ.With its ability to feature numerous hallmarks ... |
reported sensory symptoms.However, in the same study intensity discrimination ability seemed to show the opposite relationship: with lower levels of sensory symptoms seen in those who were able to better discriminate between different auditory intensities.While it is clear that further research is warranted, our findin... | Individuals show enhanced pitch discrimination, yet often find seemingly innocuous sounds distressing.This study used two behavioural experiments to examine whether an increased capacity for processing sounds in ASD could underlie both the difficulties and enhanced abilities found in the auditory domain.Autistic and no... |
CW.Averaged across crop rotations, STN at 5–10 cm was greater with the improved than the traditional cultural practice in NT and greater in NT than CT with the improved practice.Averaged across tillage, STN at 60–90 cm was greater with W-P and W-B-C-P than CW and W-B-P in the improved practice and greater in the tradit... | The STN at 20–40 cm was greater with W-P than CW and W-B-P in CT. With NT and the improved cultural practice, STN at 0–5, 5–10, 20–40, and 60–90 cm was greater with W-P and W-B-C-P than other crop rotations.The STN at 0–10 cm correlated with annualized crop residue and grain yield (r = 0.94–0.97, P ≤ 0.05). |
by their omission.Though this dataset is the largest of its kind that can be used to estimate the effects of marketing tools on condom sales, it is relatively small compared to many other analyses of advertising and price elasticities of demand.The social marketing data may contain measurement error and inconsistencies... | Social marketing organisations apply private sector marketing approaches to sell public health products.This paper investigates the impact of marketing tools, including promotion and pricing, on demand for male and female condoms in 52 countries between 1997 and 2009.Products are not equally affected: female condoms ar... |
to prostanoids .COX-2 is expressed at the site of inflammation or induced by cytokines, growth factors, and hormones .Homeostatic functions and the pathological roles played by COX-2 have been well established .Like other early-response gene products, it is one of the widest biomarkers used to evaluate the mechanism of... | Recent adverse herb reactions have stimulated interest documenting the safety profile of medicinal agents.Thus, subacute and subchronic oral toxicity of the hydroethanolic extract of Acridocarpus smeathmannii root (HEASR) in Wistar rats was investigated.In the 28 and 90-day subacute and subchronic toxicity tests, sixty... |
after CFC.The analysis of T286-autophosphorylation is consistent with our finding that structural LTP does not underlie contextual fear memory formation in aged mice.Work with T286-autophosphorylation-deficient mutant mice has suggested that generation of MISs can enable contextual fear memory formation when LTP is blo... | Although aging is associated with impaired memory formation, it is not known whether the synaptic underpinnings of memory storage differ with age.Using a training schedule that results in the same behavioral memory formation in young and aged mice, we examined synapse ultrastructure and molecular signaling in the hippo... |
detected an LTP-like strengthening of synapses after CFC in young mice, this was not observed in aged mice.Therefore, we conclude that aged mice do not use NMDA receptor-dependent LTP, or any other type of LTP, to store contextual fear memory.It is conceivable that in old age the increased threshold for LTP induction m... | Long-lasting changes at synapses enable memory storage in the brain.Instead, old-age memory was correlated with generation of multi-innervated dendritic spines (MISs), which are predominantly two-input synapses formed by the attraction of an additional excitatory, presynaptic terminal onto an existing synapse.According... |
and then 25 μM menadione was added to generate oxidative damage within the cells and incubated for a further 1 h. Cells were washed and DNA was isolated using the DNeasy Blood and Tissue kit from Qiagen, quantitated using the Picogreen Assay, and then the extent of oxidative damage was assessed by a quantitative PCR as... | A series of mitochondria-targeted antioxidants comprising a lipophilic triphenylphosphonium cation attached to the antioxidant chroman moiety of vitamin E by an alkyl linker have been prepared.The synthesis of a series of mitochondria-targeted vitamin E derivatives with a range of alkyl linkers gave compounds of differ... |
Using antibodies against AngII receptors we have detected their distribution in human adipose tissue .Specifically, we demonstrated that AT1 and AT2 receptors are co-localized with stromal cells expressing PDGF receptor beta.Furthermore, AT1 expressing cells were found in the close proximity to CD31-positive endothelia... | This article contains results of analyses of angiotensin II receptors expression in human adipose tissue and stem/stromal cells isolated from adipose tissue.We also provide here data regarding the effect of angiotensin II on intracellular calcium mobilization in adipose tissue derived stem/stromal cells (ADSCs).Discuss... |
compound in the soil.This study therefore showed that emissions of different gases are not influenced by the same factors in the same way.The amount of NO emissions depend on the area/soil volume that received KNO3 and C fertiliser, while the scale of N2O and N2 emissions depends on the amount of the applied KNO3 and a... | Agricultural soils are a major source of nitric- (NO) and nitrous oxide (N2O), which are produced and consumed by biotic and abiotic soil processes.The dominant sources of NO and N2O are microbial nitrification and denitrification, and emissions of NO and N2O generally increase after fertiliser application.The present ... |
Millions of patients worldwide suffer from serious diseases such as bradycardia, fibrillation or diabetes, and consequently require active medical implants.Size, weight, and reliability are fundamental characteristics of these devices, and are typically determined by the power source utilised.Active medical implants ar... | They represent an attractive alternative to lithium batteries to power implantable devices, as they work at body temperature, are light and easy-to-miniaturise.To be implantable in blood vessels, EBFCs should not only be made of non-toxic and biocompatible compounds but should also be able to operate in continuous flow... |
exhibit in fact a rapid decay in performance, with most lasting only a few hours.In order to determine the long-term stability of the CFEBFC it was decided to record the power output during continuous operation for one month.To the best of our knowledge, this is the first study performed over such a period of time with... | Enzymatic biofuel cells (EBFCs) can generate energy from metabolites present in physiological fluids.With this study, we demonstrate for the first time continuous power generation by flow through miniature enzymatic biofuel cells fed with an aerated solution of glucose and no redox mediators.Non-toxic highly porous gol... |
these reductions might not look dramatic in absolute terms, but it is an important fraction of water supplies for several irrigation areas as observed in Fig. 6).In the absence of an effective harmonization between water and agricultural policies in the EU, the tension between environmental policy objectives and market... | While a large number of descriptive studies have delineated the interlinkages between water, food and energy resources in the last decade, there is still need for systematic conceptualization of resource nexus interconnections.This paper proposes a theory of relational analysis of the nexus based on the analytical conc... |
We tackle unsupervised domain adaptation by accounting for the fact that different domains may need to be processed differently to arrive to a common feature representation effective for recognition.To this end, we introduce a deep learning framework where each domain undergoes a different sequence of operations, allow... | A Multiflow Network is a dynamic architecture for domain adaptation that learns potentially different computational graphs per domain, so as to map them to a common representation where inference can be performed in a domain-agnostic fashion. |
piezoelectric response.This result suggests that the field dependencies of the underlying mechanism that give rise to the linear dependence in the dielectric and piezoelectric responses with field amplitude are either the same or correlated.Change in the extent of domain reversal and contribution of domain reversal to ... | The contribution of 180° domain wall motion to polarization and dielectric properties of ferroelectric materials has yet to be determined experimentally.In this paper, an approach for estimating the extent of (180°) domain reversal during application of electric fields is presented.We demonstrate this method by determi... |
The robustness of neural networks to adversarial examples has received great attention due to security implications.Despite various attack approaches to crafting visually imperceptible adversarial examples, little has been developed towards a comprehensive measure of robustness.In this paper, we provide theoretical jus... | We propose the first attack-independent robustness metric, a.k.a CLEVER, that can be applied to any neural network classifier. |
farmers do not gain appreciably from planting CBSD-free cuttings of this variety, since infected plants are tolerant to CBSD and rarely express symptoms in the tuberous roots.As we have shown through this study, there is therefore little difference in the yield of CBSD-free versus CBSD-infected plants.By contrast, the ... | Cassava viruses are the major biotic constraint to cassava production in Africa.Community-wide action to manage them has not been attempted since a successful cassava mosaic disease control programme in the 1930s/40 s in Uganda.A pilot initiative to investigate the effectiveness of community phytosanitation for managin... |
great potential savings in terms of public expenditure on improving mental well-being.Further research on the mechanisms in which these effects take place is also warranted.The epidemiological literature points to a number of potential mechanisms supportive of a positive relationship between fruit and vegetable consump... | Rationale: While the role of diet in influencing physical health is now well-established, some recent research suggests that increased consumption of fruits and vegetables could play a role in enhancing mental well-being.A limitation with much of this existing research is its reliance on cross-sectional correlations, c... |
were 1.6 and 1.3, respectively.There was no significant linear relationship between the spectral slopes of c and cp and TSM or Chl a concentrations.Although the power law did not describe particle scattering spectra for the whole dataset, there was relatively strong linear relationship between Chl a concentration and t... | The spectral variations in the attenuation and scattering coefficients measured with a hyperspectral ac-spectra (Wetlabs) instrument were analyzed from a dataset collected in the vicinity of commercial harbors on the Estonian coast of the Gulf of Finland, Baltic Sea.In total, the measured TSM concentration varied from ... |
structure are tetravalent, thus incorporation of non-tetravalent cations will require charge-balancing cation-exchange reactions.The most abundant non-tetravalent cations are ΣREE and P, which show a strong positive correlation.However, in nearly all zircons, P2O5 contents are too low to completely charge-balance triva... | They contain up to 1212ppmw H2O, 1.9wt.% Y2O3 and 0.6wt.% P2O5 and are generally strongly zoned.This interpretation is consistent with FTIR data of the Vema zircons, which shows a strongly polarised main absorption band at ca.3100cm-1, similar to experimentally grown Lu-doped hydrous zircon.The size of this 3100cm-1 ba... |
or intrinsic crystal growth processes related to varying diffusivities of major and trace elements in the boundary layer surrounding the growing crystal.As diffusivities of most elements in zircon are low, oscillatory zoning will be preserved during continued crystal growth.Sector zoning has been related to different c... | The water and trace element contents of natural igneous zircons were determined to constrain the mechanism of hydrogen incorporation.On an atomic basis, this excess is closely approximated by the amount of H present in the zircons.We therefore conclude that H is incorporated by a charge-balance mechanism (H++REE3+=Zr4+... |
Raw data associated with this article are publicly available and can be found on the Open Science Framework at https://osf.io/xy5g6/,The study data was carried out in accordance with the code of ethics of the world medical association for experiments involving humans.Data collection was performed through Amazon Mechani... | The data presented in this article are related to the research article entitled “Does Pokémon Go lead to a more physically active life style?” (Gabbiadini et al., in press) [1].In the study, 981 individuals completed a web survey, in which frequency of Pokémon Go usage, overall physically active behavior, and amount of... |
varying amounts of electroactive material with a mixture of iron sulphide and PTFE.The chemicals and materials used to develop our electrode formulations were of the following specifications.Iron powder from Alfa Aesar,Iron sulphide from Sigma Aldrich,PTFE from Alfa Aesar,Nickel foam from Sigma Aldrich,Essentially, str... | Aiming to develop a cost effective means to store large amounts of electric energy, NiFe batteries were produced and tested under galvanostatic conditions at room temperature.Multiple regression analysis was conducted to develop predictive equations that establish a link between hydrogen evolution and electrode manufac... |
Raw data were generated in three separate waves by MTurk and Qualtrics."These data were downloaded and processed using Stata to create the final dataset used by O'Grady, Vandegrift, Burr and Wolek .This section briefly describes the raw data files, the Stata processing script, and final dataset."Data collection from Am... | We present novel data linking other-regarding behavior outside of a laboratory with a participant's moral foundations, demographics, and opinions/awareness of social problems.These data were originally collected for Study 2 of O'Grady et al.(2019).Mturk workers located in the United States and meeting MTurk's “Masters ... |
relevant to your thinking?,We eliminated participants that responded somewhat relevant, very relevant, and extremely relevant to this question.The second MFQ question asks respondents to indicate their level of agreement or disagreement with the statement “It is better to do good than to do bad.,We eliminated participa... | Anonymous, paid participants were recruited through the online labor market Amazon Mechanical Turk (MTurk).(2009) to classify participants based on their moral intuitions.After participants completed the MFQ and six diversion questions about their opinions and awareness of current social problems, we measured other-reg... |
mice.However, we previously found that Ndrg2+/+ and Ndrg2+/- mice are comparable with regard to general behaviors such as locomotor activity.Therefore, we speculate that although the protein levels of NDRG2 may be different between Ndrg2+/+APP/PS1 or Ndrg2+/-APP/PS1 mice, Ndrg2+/-APP/PS1 mice still have the ability to ... | Alzheimer's disease (AD) is a chronic degenerative disease of the central nervous system and the most common dementia type in elderly people.N-myc downstream-regulated gene 2 (NDRG2), a cell stress response gene, is primarily expressed in astrocytes in mammalian brains.The hippocampal protein levels of NDRG2 in AD pati... |
Cancer development is driven by the acquisition of somatic genetic variation that includes point mutations, copy-number variations, and large chromosome rearrangements or duplications.These events can result in a fitness advantage and cancer progression, but they are most often detrimental to cellular fitness.While som... | Here, we analyze recently published genomics, transcriptomics, and proteomics datasets made available by CPTAC and TCGA consortia on 282 breast, ovarian, and colorectal tumor samples to investigate the impact of CNVs in the proteomes of these cells.This study highlights the importance of post-transcriptional mechanisms... |
the variability measured due to post-transcriptional and post-translational regulation."Then a second linear model is performed to calculate the association between Py’ and the CNV of Px,:Py' = β.Px +ψ,Statistical significance is estimated by calculating an F statistic over an F-distribution, p-values are then adjusted... | Copy-number variations (CNVs) are ubiquitous in cancer and often act as driver events, but the effects of CNVs on the proteome of tumors are poorly understood.We found that CNVs are buffered by post-transcriptional regulation in 23%–33% of proteins that are significantly enriched in protein complex members.We identifie... |
in multi-atlas segmentation methods.In our work, K was predefined globally, which means that the same number of atlases are selected at each location in the target image.However, it is observed that K required for the highest segmentation accuracy varies for different structures.This could also be the case for differen... | An automated segmentation method is presented for multi-organ segmentation in abdominal CT images.Dictionary learning and sparse coding techniques are used in the proposed method to generate target specific priors for segmentation.Based on the learnt dictionaries and classifiers, probabilistic atlases are then generate... |
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